|
Name |
Accession |
Description |
Interval |
E-value |
| fabF |
TIGR03150 |
beta-ketoacyl-acyl-carrier-protein synthase II; 3-oxoacyl-[acyl-carrier-protein] synthase 2 ... |
4-409 |
0e+00 |
|
beta-ketoacyl-acyl-carrier-protein synthase II; 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis]
Pssm-ID: 274452 [Multi-domain] Cd Length: 407 Bit Score: 762.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 4 RRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVRDFDPALVLDLKSIRKTDVFVQFAMESAR 83
Cdd:TIGR03150 1 RRVVVTGLGAVTPLGNGVEEFWENLLAGKSGIGPITRFDASDLPVKIAGEVKDFDPEDYIDKKEARRMDRFIQYALAAAK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 84 QAWEDSGLEINETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKGPNISIVTA 163
Cdd:TIGR03150 81 EAVEDSGLDIEEEDAERVGVIIGSGIGGLETIEEQHIVLLEKGPRRVSPFFIPMSIINMAAGQISIRYGAKGPNHAVVTA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 164 CTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTRNDEPEKASRPWDKGRDGFVLGEGAACVVVEE 243
Cdd:TIGR03150 161 CATGTHAIGDAFRLIQRGDADVMIAGGAEAAITPLGIAGFAAMKALSTRNDDPEKASRPFDKDRDGFVMGEGAGVLVLEE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 244 LEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEARAIKKTF 323
Cdd:TIGR03150 241 LEHAKARGAKIYAEIVGYGMSGDAYHITAPAPEGEGAARAMRAALKDAGINPEDVDYINAHGTSTPLGDKAETKAIKKVF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 324 GDHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAREMKIDTVMSNSFGFGGT 403
Cdd:TIGR03150 321 GDHAYKLAVSSTKSMTGHLLGAAGAIEAIFTVLAIRDGIVPPTINLDNPDPECDLDYVPNEAREAKIDYALSNSFGFGGT 400
|
....*.
gi 29653839 404 NGTLVL 409
Cdd:TIGR03150 401 NASLVF 406
|
|
| PRK07314 |
PRK07314 |
beta-ketoacyl-ACP synthase II; |
3-412 |
0e+00 |
|
beta-ketoacyl-ACP synthase II;
Pssm-ID: 235987 [Multi-domain] Cd Length: 411 Bit Score: 739.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 3 KRRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVRDFDPALVLDLKSIRKTDVFVQFAMESA 82
Cdd:PRK07314 1 KRRVVVTGLGAVSPLGNDVESTWKNLLAGKSGIGPITHFDTSDLAVKIAGEVKDFNPDDYMSRKEARRMDRFIQYGIAAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 83 RQAWEDSGLEINETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKGPNISIVT 162
Cdd:PRK07314 81 KQAVEDAGLEITEENADRIGVIIGSGIGGLETIEEQHITLLEKGPRRVSPFFVPMAIINMAAGHVSIRYGAKGPNHSIVT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 163 ACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTRNDEPEKASRPWDKGRDGFVLGEGAACVVVE 242
Cdd:PRK07314 161 ACATGAHAIGDAARLIAYGDADVMVAGGAEAAITPLGIAGFAAARALSTRNDDPERASRPFDKDRDGFVMGEGAGILVLE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 243 ELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEARAIKKT 322
Cdd:PRK07314 241 ELEHAKARGAKIYAEVVGYGMTGDAYHMTAPAPDGEGAARAMKLALKDAGINPEDIDYINAHGTSTPAGDKAETQAIKRV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 323 FGDHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAREMKIDTVMSNSFGFGG 402
Cdd:PRK07314 321 FGEHAYKVAVSSTKSMTGHLLGAAGAVEAIFSVLAIRDQVIPPTINLDNPDEECDLDYVPNEARERKIDYALSNSFGFGG 400
|
410
....*....|
gi 29653839 403 TNGTLVLSRV 412
Cdd:PRK07314 401 TNASLVFKRY 410
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
4-412 |
0e+00 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 713.79 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 4 RRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVRDFDPALVLDLKSIRKTDVFVQFAMESAR 83
Cdd:COG0304 1 RRVVITGLGAVSPLGNGVEEFWEALLAGRSGIRPITRFDASGLPVRIAGEVKDFDPEEYLDRKELRRMDRFTQYALAAAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 84 QAWEDSGLEINETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKGPNISIVTA 163
Cdd:COG0304 81 EALADAGLDLDEVDPDRTGVIIGSGIGGLDTLEEAYRALLEKGPRRVSPFFVPMMMPNMAAGHVSIRFGLKGPNYTVSTA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 164 CTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTRNDEPEKASRPWDKGRDGFVLGEGAACVVVEE 243
Cdd:COG0304 161 CASGAHAIGEAYRLIRRGRADVMIAGGAEAAITPLGLAGFDALGALSTRNDDPEKASRPFDKDRDGFVLGEGAGVLVLEE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 244 LEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEARAIKKTF 323
Cdd:COG0304 241 LEHAKARGAKIYAEVVGYGASSDAYHITAPAPDGEGAARAMRAALKDAGLSPEDIDYINAHGTSTPLGDAAETKAIKRVF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 324 GDHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAREMKIDTVMSNSFGFGGT 403
Cdd:COG0304 321 GDHAYKVPVSSTKSMTGHLLGAAGAIEAIASVLALRDGVIPPTINLENPDPECDLDYVPNEAREAKIDYALSNSFGFGGH 400
|
....*....
gi 29653839 404 NGTLVLSRV 412
Cdd:COG0304 401 NASLVFKRY 409
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
4-409 |
0e+00 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 659.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 4 RRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVRDFDPALVLDLKSIRKTDVFVQFAMESAR 83
Cdd:cd00834 1 RRVVITGLGAVTPLGNGVEEFWEALLAGRSGIRPITRFDASGFPSRIAGEVPDFDPEDYLDRKELRRMDRFAQFALAAAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 84 QAWEDSGLEINETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKGPNISIVTA 163
Cdd:cd00834 81 EALADAGLDPEELDPERIGVVIGSGIGGLATIEEAYRALLEKGPRRVSPFFVPMALPNMAAGQVAIRLGLRGPNYTVSTA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 164 CTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTRNDEPEKASRPWDKGRDGFVLGEGAACVVVEE 243
Cdd:cd00834 161 CASGAHAIGDAARLIRLGRADVVIAGGAEALITPLTLAGFAALRALSTRNDDPEKASRPFDKDRDGFVLGEGAGVLVLES 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 244 LEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEARAIKKTF 323
Cdd:cd00834 241 LEHAKARGAKIYAEILGYGASSDAYHITAPDPDGEGAARAMRAALADAGLSPEDIDYINAHGTSTPLNDAAESKAIKRVF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 324 GDHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAREMKIDTVMSNSFGFGGT 403
Cdd:cd00834 321 GEHAKKVPVSSTKSMTGHLLGAAGAVEAIATLLALRDGVLPPTINLEEPDPECDLDYVPNEAREAPIRYALSNSFGFGGH 400
|
....*.
gi 29653839 404 NGTLVL 409
Cdd:cd00834 401 NASLVF 406
|
|
| PRK08722 |
PRK08722 |
beta-ketoacyl-ACP synthase II; |
1-412 |
0e+00 |
|
beta-ketoacyl-ACP synthase II;
Pssm-ID: 181539 [Multi-domain] Cd Length: 414 Bit Score: 548.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 1 MEKRRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVRDFDPALVLDLKSIRKTDVFVQFAME 80
Cdd:PRK08722 1 MSKRRVVVTGMGMLSPVGNTVESSWKALLAGQSGIVNIEHFDTTNFSTRFAGLVKDFNCEEYMSKKDARKMDLFIQYGIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 81 SARQAWEDSGLEINETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKGPNISI 160
Cdd:PRK08722 81 AGIQALDDSGLEVTEENAHRIGVAIGSGIGGLGLIEAGHQALVEKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 161 VTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTRNDEPEKASRPWDKGRDGFVLGEGAACVV 240
Cdd:PRK08722 161 STACTTGLHNIGHAARMIAYGDADAMVAGGAEKASTPLGMAGFGAAKALSTRNDEPQKASRPWDKDRDGFVLGDGAGMMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 241 VEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEARAIK 320
Cdd:PRK08722 241 LEEYEHAKARGAKIYAELVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDAGVTGEQIGYVNAHGTSTPAGDVAEIKGIK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 321 KTFGDH-AYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAREMK-IDTVMSNSF 398
Cdd:PRK08722 321 RALGEAgSKQVLVSSTKSMTGHLLGAAGSVEAIITVMSLVDQIVPPTINLDDPEEGLDIDLVPHTARKVEsMEYAICNSF 400
|
410
....*....|....
gi 29653839 399 GFGGTNGTLVLSRV 412
Cdd:PRK08722 401 GFGGTNGSLIFKKM 414
|
|
| PRK06333 |
PRK06333 |
beta-ketoacyl-ACP synthase; |
1-411 |
0e+00 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235781 [Multi-domain] Cd Length: 424 Bit Score: 542.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 1 MEKRRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVRD--------FDPALVLDLKSIRKTD 72
Cdd:PRK06333 1 MNKKRIVVTGMGAVSPLGCGVETFWQRLLAGQSGIRTLTDFPVGDLATKIGGQVPDlaedaeagFDPDRYLDPKDQRKMD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 73 VFVQFAMESARQAWEDSGLEINETNAP-RVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKY 151
Cdd:PRK06333 81 RFILFAMAAAKEALAQAGWDPDTLEDReRTATIIGSGVGGFPAIAEAVRTLDSRGPRRLSPFTIPSFLTNMAAGHVSIRY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 152 DLKGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTR-NDEPEKASRPWDKGRDGF 230
Cdd:PRK06333 161 GFKGPLGAPVTACAAGVQAIGDAARLIRSGEADVAVCGGTEAAIDRVSLAGFAAARALSTRfNDAPEQASRPFDRDRDGF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 231 VLGEGAACVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPA 310
Cdd:PRK06333 241 VMGEGAGILVIETLEHALARGAPPLAELVGYGTSADAYHMTAGPEDGEGARRAMLIALRQAGIPPEEVQHLNAHATSTPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 311 ADPLEARAIKKTFGdHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCD-LDFVPNEAREMK 389
Cdd:PRK06333 321 GDLGEVAAIKKVFG-HVSGLAVSSTKSATGHLLGAAGGVEAIFTILALRDQIAPPTLNLENPDPAAEgLDVVANKARPMD 399
|
410 420
....*....|....*....|..
gi 29653839 390 IDTVMSNSFGFGGTNGTLVLSR 411
Cdd:PRK06333 400 MDYALSNGFGFGGVNASILFRR 421
|
|
| PRK08439 |
PRK08439 |
3-oxoacyl-(acyl carrier protein) synthase II; Reviewed |
4-412 |
0e+00 |
|
3-oxoacyl-(acyl carrier protein) synthase II; Reviewed
Pssm-ID: 236265 [Multi-domain] Cd Length: 406 Bit Score: 542.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 4 RRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVRDFDPALVLDLKSIRKTDVFVQFAMESAR 83
Cdd:PRK08439 2 KRVVVTGIGMINSLGLNKESSFKAICNGECGIKKITLFDASDFPVQIAGEITDFDPTEVMDPKEVKKADRFIQLGLKAAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 84 QAWEDSGLEINETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKGPNISIVTA 163
Cdd:PRK08439 82 EAMKDAGFLPEELDAERFGVSSASGIGGLPNIEKNSIICFEKGPRKISPFFIPSALVNMLGGFISIEHGLKGPNLSSVTA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 164 CTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTRNDEPEKASRPWDKGRDGFVLGEGAACVVVEE 243
Cdd:PRK08439 162 CAAGTHAIIEAVKTIMLGGADKMLVVGAESAICPVGIGGFAAMKALSTRNDDPKKASRPFDKDRDGFVMGEGAGALVLEE 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 244 LEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPeaEGFTTCMKNSLRDAGiaPERVDYINAHGTSTPAADPLEARAIKKTF 323
Cdd:PRK08439 242 YESAKKRGAKIYAEIIGFGESGDANHITSPAP--EGPLRAMKAALEMAG--NPKIDYINAHGTSTPYNDKNETAALKELF 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 324 GDHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAREMKIDTVMSNSFGFGGT 403
Cdd:PRK08439 318 GSKEKVPPVSSTKGQIGHCLGAAGAIEAVISIMAMRDGILPPTINQETPDPECDLDYIPNVARKAELNVVMSNSFGFGGT 397
|
....*....
gi 29653839 404 NGTLVLSRV 412
Cdd:PRK08439 398 NGVVIFKKV 406
|
|
| PTZ00050 |
PTZ00050 |
3-oxoacyl-acyl carrier protein synthase; Provisional |
13-412 |
1.54e-169 |
|
3-oxoacyl-acyl carrier protein synthase; Provisional
Pssm-ID: 240245 [Multi-domain] Cd Length: 421 Bit Score: 481.11 E-value: 1.54e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 13 VVSPLGNKVSDMWQALLAGKSGVKPITRFDA----------------SSFPTQIAAEVR--DFDPalvLDLKSIRKTDVF 74
Cdd:PTZ00050 1 VVTPLGVGAESTWEALIAGKSGIRKLTEFPKflpdcipeqkalenlvAAMPCQIAAEVDqsEFDP---SDFAPTKRESRA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 75 VQFAMESARQAWEDSGLEI-NETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDL 153
Cdd:PTZ00050 78 THFAMAAAREALADAKLDIlSEKDQERIGVNIGSGIGSLADLTDEMKTLYEKGHSRVSPYFIPKILGNMAAGLVAIKHKL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 154 KGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTR-NDEPEKASRPWDKGRDGFVL 232
Cdd:PTZ00050 158 KGPSGSAVTACATGAHCIGEAFRWIKYGEADIMICGGTEASITPVSFAGFSRMRALCTKyNDDPQRASRPFDKDRAGFVM 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 233 GEGAACVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPER-VDYINAHGTSTPAA 311
Cdd:PTZ00050 238 GEGAGILVLEELEHALRRGAKIYAEIRGYGSSSDAHHITAPHPDGRGARRCMENALKDGANININdVDYVNAHATSTPIG 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 312 DPLEARAIKKTFGDH-AYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAR--EM 388
Cdd:PTZ00050 318 DKIELKAIKKVFGDSgAPKLYVSSTKGGLGHLLGAAGAVESIVTILSLYEQIIPPTINLENPDAECDLNLVQGKTAhpLQ 397
|
410 420
....*....|....*....|....
gi 29653839 389 KIDTVMSNSFGFGGTNGTLVLSRV 412
Cdd:PTZ00050 398 SIDAVLSTSFGFGGVNTALLFTKY 421
|
|
| PLN02836 |
PLN02836 |
3-oxoacyl-[acyl-carrier-protein] synthase |
4-412 |
3.18e-153 |
|
3-oxoacyl-[acyl-carrier-protein] synthase
Pssm-ID: 215449 [Multi-domain] Cd Length: 437 Bit Score: 440.38 E-value: 3.18e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 4 RRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDA--------------SSFPTQIAAEV------RDFDPALVL 63
Cdd:PLN02836 6 RRVVVTGLGLVTPLGCGVETTWRRLIAGECGVRALTQDDLkmksedeetqlytlDQLPSRVAALVprgtgpGDFDEELWL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 64 DLKSIRKtdvFVQFAMESARQAWEDSG-LEINETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINM 142
Cdd:PLN02836 86 NSRSSSR---FIGYALCAADEALSDARwLPSEDEAKERTGVSIGGGIGSITDILEAAQLICEKRLRRLSPFFVPRILINM 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 143 ASGMVSIKYDLKGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTR-NDEPEKASR 221
Cdd:PLN02836 163 AAGHVSIRYGFQGPNHAAVTACATGAHSIGDAFRMIQFGDADVMVAGGTESSIDALSIAGFSRSRALSTKfNSCPTEASR 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 222 PWDKGRDGFVLGEGAACVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYI 301
Cdd:PLN02836 243 PFDCDRDGFVIGEGAGVLVLEELEHAKRRGAKIYAEVRGYGMSGDAHHITQPHEDGRGAVLAMTRALQQSGLHPNQVDYV 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 302 NAHGTSTPAADPLEARAIKKTFGDHAY--KLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLD 379
Cdd:PLN02836 323 NAHATSTPLGDAVEARAIKTVFSEHATsgGLAFSSTKGATGHLLGAAGAVEAIFSVLAIHHGIAPPTLNLERPDPIFDDG 402
|
410 420 430
....*....|....*....|....*....|....
gi 29653839 380 FVP-NEAREMKIDTVMSNSFGFGGTNGTLVLSRV 412
Cdd:PLN02836 403 FVPlTASKAMLIRAALSNSFGFGGTNASLLFTSP 436
|
|
| PLN02787 |
PLN02787 |
3-oxoacyl-[acyl-carrier-protein] synthase II |
1-410 |
6.70e-137 |
|
3-oxoacyl-[acyl-carrier-protein] synthase II
Pssm-ID: 215421 [Multi-domain] Cd Length: 540 Bit Score: 402.43 E-value: 6.70e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 1 MEKRRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVRDFDPALVLDLKSIRKTDVFVQFAME 80
Cdd:PLN02787 126 TKQRRVVVTGMGVVSPLGHDPDVFYNNLLEGVSGISEIERFDCSQFPTRIAGEIKSFSTDGWVAPKLSKRMDKFMLYLLT 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 81 SARQAWEDSGLE---INETNAPRVGVAIGSGIGGMPWIEKNYDALLTSgPRKISPFFIPGAIINMASGMVSIKYDLKGPN 157
Cdd:PLN02787 206 AGKKALADGGITedvMKELDKTKCGVLIGSAMGGMKVFNDAIEALRIS-YRKMNPFCVPFATTNMGSAMLAMDLGWMGPN 284
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 158 ISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTRNDEPEKASRPWDKGRDGFVLGEGAA 237
Cdd:PLN02787 285 YSISTACATSNFCILNAANHIIRGEADVMLCGGSDAAIIPIGLGGFVACRALSQRNDDPTKASRPWDMNRDGFVMGEGAG 364
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 238 CVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEAR 317
Cdd:PLN02787 365 VLLLEELEHAKKRGANIYAEFLGGSFTCDAYHMTEPHPEGAGVILCIEKALAQSGVSKEDVNYINAHATSTKAGDLKEYQ 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 318 AIKKTFGDHAyKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLD-FVPNEAREMKIDTVMSN 396
Cdd:PLN02787 445 ALMRCFGQNP-ELRVNSTKSMIGHLLGAAGAVEAIATVQAIRTGWVHPNINLENPESGVDTKvLVGPKKERLDIKVALSN 523
|
410
....*....|....
gi 29653839 397 SFGFGGTNGTLVLS 410
Cdd:PLN02787 524 SFGFGGHNSSILFA 537
|
|
| PRK07967 |
PRK07967 |
beta-ketoacyl-ACP synthase I; |
4-412 |
5.45e-114 |
|
beta-ketoacyl-ACP synthase I;
Pssm-ID: 181184 [Multi-domain] Cd Length: 406 Bit Score: 339.34 E-value: 5.45e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 4 RRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVrDFDPALVLDLKSIR---KTDVFVQFAME 80
Cdd:PRK07967 2 RRVVITGLGIVSSIGNNQQEVLASLREGRSGITFSPEFAEMGMRSQVWGNV-KLDPTGLIDRKVMRfmgDASAYAYLAME 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 81 sarQAWEDSGLEINETNAPRVGVAIGSGIGGMPWIEKNYDALLTS-GPRKISPFFIPGAIINMASGMVSIKYDLKGPNIS 159
Cdd:PRK07967 81 ---QAIADAGLSEEQVSNPRTGLIAGSGGGSTRNQVEAADAMRGPrGPKRVGPYAVTKAMASTVSACLATPFKIKGVNYS 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 160 IVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGgFAAVRALSTR-NDEPEKASRPWDKGRDGFVLGEGAAC 238
Cdd:PRK07967 158 ISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELDWEMSCL-FDAMGALSTKyNDTPEKASRAYDANRDGFVIAGGGGV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 239 VVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRpdPEAEGFTTCMKNSLRDAGiapERVDYINAHGTSTPAADPLEARA 318
Cdd:PRK07967 237 VVVEELEHALARGAKIYAEIVGYGATSDGYDMVA--PSGEGAVRCMQMALATVD---TPIDYINTHGTSTPVGDVKELGA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 319 IKKTFGDHAykLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEG-CDLDFVPNEAREMKIDTVMSNS 397
Cdd:PRK07967 312 IREVFGDKS--PAISATKSLTGHSLGAAGVQEAIYSLLMMEHGFIAPSANIEELDPQaAGMPIVTETTDNAELTTVMSNS 389
|
410
....*....|....*
gi 29653839 398 FGFGGTNGTLVLSRV 412
Cdd:PRK07967 390 FGFGGTNATLVFRRY 404
|
|
| PRK06501 |
PRK06501 |
beta-ketoacyl-ACP synthase; |
6-411 |
7.40e-113 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235817 [Multi-domain] Cd Length: 425 Bit Score: 336.99 E-value: 7.40e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 6 VVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVrDFdpalvLDLKSIRKTDVFVQFAMESARQA 85
Cdd:PRK06501 13 VAVTGMGVVTSLGQGKADNWAALTAGESGIHTITRFPTEGLRTRIAGTV-DF-----LPESPFGASALSEALARLAAEEA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 86 WEDSGLEINETNAP--------------RVGVAIGSGIGGMPwiekNYDALLT-SGPRKISPF---FIPGAIinmaSGMV 147
Cdd:PRK06501 87 LAQAGIGKGDFPGPlflaappvelewpaRFALAAAVGDNDAP----SYDRLLRaARGGRFDALherFQFGSI----ADRL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 148 SIKYDLKGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTRNDEPEKASRPWDKGR 227
Cdd:PRK06501 159 ADRFGTRGLPISLSTACASGATAIQLGVEAIRRGETDRALCIATDGSVSAEALIRFSLLSALSTQNDPPEKASKPFSKDR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 228 DGFVLGEGAACVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTS 307
Cdd:PRK06501 239 DGFVMAEGAGALVLESLESAVARGAKILGIVAGCGEKADSFHRTRSSPDGSPAIGAIRAALADAGLTPEQIDYINAHGTS 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 308 TPAADPLEARAIKKTFGDHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEARE 387
Cdd:PRK06501 319 TPENDKMEYLGLSAVFGERLASIPVSSNKSMIGHTLTAAGAVEAVFSLLTIQTGRLPPTINYDNPDPAIPLDVVPNVARD 398
|
410 420
....*....|....*....|....
gi 29653839 388 MKIDTVMSNSFGFGGTNGTLVLSR 411
Cdd:PRK06501 399 ARVTAVLSNSFGFGGQNASLVLTA 422
|
|
| PRK09116 |
PRK09116 |
beta-ketoacyl-ACP synthase; |
4-409 |
2.47e-106 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 181657 [Multi-domain] Cd Length: 405 Bit Score: 319.63 E-value: 2.47e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 4 RRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFD-ASSFPTQIAAEVRDFDPALVLDLKSIRKTDVFVQFAMESA 82
Cdd:PRK09116 2 RRVVVTGMGGVTALGEDWQTIAARLKAGRNAVRRMPEWDrYDGLNTRLAAPIDDFELPAHYTRKKIRSMGRVSLMATRAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 83 RQAWEDSGLEINE--TNApRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPffipGAIINM----ASGMVSIKYDLKGP 156
Cdd:PRK09116 82 ELALEDAGLLGDPilTDG-RMGIAYGSSTGSTDPIGAFGTMLLEGSMSGITA----TTYVRMmphtTAVNVGLFFGLKGR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 157 NISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMAStPLGIGGFAAVRALSTRNDEPEKASRPWDKGRDGFVLGEGA 236
Cdd:PRK09116 157 VIPTSSACTSGSQGIGYAYEAIKYGYQTVMLAGGAEELC-PTEAAVFDTLFATSTRNDAPELTPRPFDANRDGLVIGEGA 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 237 ACVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGftTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEA 316
Cdd:PRK09116 236 GTLVLEELEHAKARGATIYAEIVGFGTNSDGAHVTQPQAETMQ--IAMELALKDAGLAPEDIGYVNAHGTATDRGDIAES 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 317 RAIKKTFGDhayKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGC-DLDFVPNEAREMKIDTVMS 395
Cdd:PRK09116 314 QATAAVFGA---RMPISSLKSYFGHTLGACGALEAWMSIEMMNEGWFAPTLNLTQVDPACgALDYIMGEAREIDTEYVMS 390
|
410
....*....|....
gi 29653839 396 NSFGFGGTNGTLVL 409
Cdd:PRK09116 391 NNFAFGGINTSLIF 404
|
|
| PRK07910 |
PRK07910 |
beta-ketoacyl-ACP synthase; |
6-411 |
4.20e-105 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 236129 [Multi-domain] Cd Length: 418 Bit Score: 317.06 E-value: 4.20e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 6 VVITGLGVVSPLGNKVSDMWQALLAGKSGVKP-----ITRFDassFPTQIAAE-VRDFDPALVLdlKSIRKTDVFVQFAM 79
Cdd:PRK07910 14 VVVTGIAMTTALATDAETTWKLLLDGQSGIRTlddpfVEEFD---LPVRIGGHlLEEFDHQLTR--VELRRMSYLQRMST 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 80 ESARQAWEDSGLEinETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKGPNIS 159
Cdd:PRK07910 89 VLGRRVWENAGSP--EVDTNRLMVSIGTGLGSAEELVFAYDDMRARGLRAVSPLAVQMYMPNGPAAAVGLERHAKAGVIT 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 160 IVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRA-LSTRNDEPEKASRPWDKGRDGFVLGEGAAC 238
Cdd:PRK07910 167 PVSACASGSEAIAQAWRQIVLGEADIAICGGVETRIEAVPIAGFAQMRIvMSTNNDDPAGACRPFDKDRDGFVFGEGGAL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 239 VVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEARA 318
Cdd:PRK07910 247 MVIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAMTRAIELAGLTPGDIDHVNAHATGTSVGDVAEGKA 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 319 IKKTFGDHayKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAREMKIDTVMSNSF 398
Cdd:PRK07910 327 INNALGGH--RPAVYAPKSALGHSVGAVGAVESILTVLALRDGVIPPTLNLENLDPEIDLDVVAGEPRPGNYRYAINNSF 404
|
410
....*....|...
gi 29653839 399 GFGGTNGTLVLSR 411
Cdd:PRK07910 405 GFGGHNVALAFGR 417
|
|
| PRK14691 |
PRK14691 |
3-oxoacyl-(acyl carrier protein) synthase II; Provisional |
94-414 |
7.53e-105 |
|
3-oxoacyl-(acyl carrier protein) synthase II; Provisional
Pssm-ID: 173154 [Multi-domain] Cd Length: 342 Bit Score: 313.97 E-value: 7.53e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 94 NETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKGPNISIVTACTTGLHNIGH 173
Cdd:PRK14691 21 NTEKQERTATIIGAGIGGFPAIAHAVRTSDSRGPKRLSPFTVPSFLVNLAAGHVSIKHHFKGPIGAPVTACAAGVQAIGD 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 174 AARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTR-NDEPEKASRPWDKGRDGFVLGEGAACVVVEELEHAKKRNA 252
Cdd:PRK14691 101 AVRMIRNNEADVALCGGAEAVIDTVSLAGFAAARALSTHfNSTPEKASRPFDTARDGFVMGEGAGLLIIEELEHALARGA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 253 TIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEARAIKKTFGDhAYKLAV 332
Cdd:PRK14691 181 KPLAEIVGYGTSADAYHMTSGAEDGDGAYRAMKIALRQAGITPEQVQHLNAHATSTPVGDLGEINAIKHLFGE-SNALAI 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 333 SSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCD-LDFVPNEAREMKIDTVMSNSFGFGGTNGTLVLSR 411
Cdd:PRK14691 260 TSTKSATGHLLGAAGGLETIFTVLALRDQIVPATLNLENPDPAAKgLNIIAGNAQPHDMTYALSNGFGFAGVNASILLKR 339
|
...
gi 29653839 412 VFD 414
Cdd:PRK14691 340 WVD 342
|
|
| elong_cond_enzymes |
cd00828 |
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
4-409 |
3.45e-94 |
|
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP) thioesters as primer substrates, as well as the nature of their active site residues.
Pssm-ID: 238424 [Multi-domain] Cd Length: 407 Bit Score: 288.57 E-value: 3.45e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 4 RRVVITGLGVVSPLGNK---VSDMWQALLAGKSGVKPITRFDaSSFPTQIAAEVRDFDPAlVLDLKSIRKTDVFVQFAME 80
Cdd:cd00828 1 SRVVITGIGVVSPHGEGcdeVEEFWEALREGRSGIAPVARLK-SRFDRGVAGQIPTGDIP-GWDAKRTGIVDRTTLLALV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 81 SARQAWEDSGLEINETNAP-RVGVAIGSGIGGMPWIEKNYDALLtsgpRKISPFFIPGAI--INMASGMVSIKYDLK-GP 156
Cdd:cd00828 79 ATEEALADAGITDPYEVHPsEVGVVVGSGMGGLRFLRRGGKLDA----RAVNPYVSPKWMlsPNTVAGWVNILLLSShGP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 157 NISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEmASTPLGIGGFAAVRALSTRNDEPEKASRPWDKGRDGFVLGEGA 236
Cdd:cd00828 155 IKTPVGACATALEALDLAVEAIRSGKADIVVVGGVE-DPLEEGLSGFANMGALSTAEEEPEEMSRPFDETRDGFVEAEGA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 237 ACVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPeAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEA 316
Cdd:cd00828 234 GVLVLERAELALARGAPIYGRVAGTASTTDGAGRSVPAG-GKGIARAIRTALAKAGLSLDDLDVISAHGTSTPANDVAES 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 317 RAIKKTFGDHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAR--EMKIDTVM 394
Cdd:cd00828 313 RAIAEVAGALGAPLPVTAQKALFGHSKGAAGALQLIGALQSLEHGLIPPTANLDDVDPDVEHLSVVGLSRdlNLKVRAAL 392
|
410
....*....|....*
gi 29653839 395 SNSFGFGGTNGTLVL 409
Cdd:cd00828 393 VNAFGFGGSNAALVL 407
|
|
| PRK05952 |
PRK05952 |
beta-ketoacyl-ACP synthase; |
5-411 |
7.72e-88 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235653 [Multi-domain] Cd Length: 381 Bit Score: 271.54 E-value: 7.72e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 5 RVVITGLGVVSPLGNkVSDMWQALLAGKSGVKPITRFdassfptqiaAEVRDFDPALV----LDLKSIRKTDVfvqfame 80
Cdd:PRK05952 3 KVVVTGIGLVSALGD-LEQSWQRLLQGKSGIKLHQPF----------PELPPLPLGLIgnqpSSLEDLTKTVV------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 81 saRQAWEDSGLEINETNAprvGVAIGS--GIGGM--PWIEKNYDALLTSGPRKISPFFI---PgaiiNMASGMVSIKYDL 153
Cdd:PRK05952 65 --TAALKDAGLTPPLTDC---GVVIGSsrGCQGQweKLARQMYQGDDSPDEELDLENWLdtlP----HQAAIAAARQIGT 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 154 KGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTrndepeKASRPWDKGRDGFVLG 233
Cdd:PRK05952 136 QGPVLAPMAACATGLWAIAQGVELIQTGQCQRVIAGAVEAPITPLTLAGFQQMGALAK------TGAYPFDRQREGLVLG 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 234 EGAACVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADP 313
Cdd:PRK05952 210 EGGAILVLESAELAQKRGAKIYGQILGFGLTCDAYHMSAPEPDGKSAIAAIQQCLARSGLTPEDIDYIHAHGTATRLNDQ 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 314 LEARAIKKTFGdhaYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDegCDLDFVpNEAREMKIDTV 393
Cdd:PRK05952 290 REANLIQALFP---HRVAVSSTKGATGHTLGASGALGVAFSLLALRHQQLPPCVGLQEPE--FDLNFV-RQAQQSPLQNV 363
|
410
....*....|....*...
gi 29653839 394 MSNSFGFGGTNGTLVLSR 411
Cdd:PRK05952 364 LCLSFGFGGQNAAIALGK 381
|
|
| CLF |
cd00832 |
Chain-length factor (CLF) is a factor required for polyketide chain initiation of aromatic ... |
4-409 |
2.56e-86 |
|
Chain-length factor (CLF) is a factor required for polyketide chain initiation of aromatic antibiotic-producing polyketide synthases (PKSs) of filamentous bacteria. CLFs have been shown to have decarboxylase activity towards malonyl-acyl carrier protein (ACP). CLFs are similar to other elongation ketosynthase domains, but their active site cysteine is replaced by a conserved glutamine.
Pssm-ID: 238428 [Multi-domain] Cd Length: 399 Bit Score: 268.07 E-value: 2.56e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 4 RRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQIAAEVRDFDPALVLDLKSIRKTDVFVQFAMESAR 83
Cdd:cd00832 1 RRAVVTGIGVVAPNGLGVEEYWKAVLDGRSGLGPITRFDPSGYPARLAGEVPDFDAAEHLPGRLLPQTDRMTRLALAAAD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 84 QAWEDSGLEINETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKGPNISIVTA 163
Cdd:cd00832 81 WALADAGVDPAALPPYDMGVVTASAAGGFEFGQRELQKLWSKGPRHVSAYQSFAWFYAVNTGQISIRHGMRGPSGVVVAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 164 CTTGLHNIGHAARMIAhNDADAMIAGGTEMASTPLGIGGFAAVRALSTrNDEPEKASRPWDKGRDGFVLGEGAACVVVEE 243
Cdd:cd00832 161 QAGGLDALAQARRLVR-RGTPLVVSGGVDSALCPWGWVAQLSSGRLST-SDDPARAYLPFDAAAAGYVPGEGGAILVLED 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 244 LEHAKKRNATIYAEIIGFGMSGDAyhmtRPDP-EAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEARAIKKT 322
Cdd:cd00832 239 AAAARERGARVYGEIAGYAATFDP----PPGSgRPPGLARAIRLALADAGLTPEDVDVVFADAAGVPELDRAEAAALAAV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 323 FGDHAykLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAREMKIDTVMSNSFGFGG 402
Cdd:cd00832 315 FGPRG--VPVTAPKTMTGRLYAGGAPLDVATALLALRDGVIPPTVNVTDVPPAYGLDLVTGRPRPAALRTALVLARGRGG 392
|
....*..
gi 29653839 403 TNGTLVL 409
Cdd:cd00832 393 FNSALVV 399
|
|
| PRK07103 |
PRK07103 |
polyketide beta-ketoacyl:acyl carrier protein synthase; Validated |
5-411 |
8.33e-83 |
|
polyketide beta-ketoacyl:acyl carrier protein synthase; Validated
Pssm-ID: 180839 [Multi-domain] Cd Length: 410 Bit Score: 259.58 E-value: 8.33e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 5 RVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPITRFDASSFPTQ--------IAAEVRDFDPALVLDLKSIRKTDVFVQ 76
Cdd:PRK07103 3 EVVVTGVGVVSAIGQGRPSFAAALLAGRHAFGVMRRPGRQVPDDAgaglasafIGAELDSLALPERLDAKLLRRASLSAQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 77 FAMESARQAWEDSGLEinETNAPRVGVAIGSGIggmpwIEKNYDALL----TSGPRKISPFFIPGAIINMASGMVSIKYD 152
Cdd:PRK07103 83 AALAAAREAWRDAALG--PVDPDRIGLVVGGSN-----LQQREQALVhetyRDRPAFLRPSYGLSFMDTDLVGLCSEQFG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 153 LKGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTRN--DEPEKASRPWDKGRDGF 230
Cdd:PRK07103 156 IRGEGFTVGGASASGQLAVIQAARLVQSGSVDACIAVGALMDLSYWECQALRSLGAMGSDRfaDEPEAACRPFDQDRDGF 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 231 VLGEGAACVVVEELEHAKKRNATIYAEIIGFGMSGDAyhmTR-PDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTP 309
Cdd:PRK07103 236 IYGEACGAVVLESAESARRRGARPYAKLLGWSMRLDA---NRgPDPSLEGEMRVIRAALRRAGLGPEDIDYVNPHGTGSP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 310 AADPLEARAIKKTFGDHAYklaVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENP-DEGCdlDFVPNEAREM 388
Cdd:PRK07103 313 LGDETELAALFASGLAHAW---INATKSLTGHGLSAAGIVELIATLLQMRAGFLHPSRNLDEPiDERF--RWVGSTAESA 387
|
410 420
....*....|....*....|...
gi 29653839 389 KIDTVMSNSFGFGGTNGTLVLSR 411
Cdd:PRK07103 388 RIRYALSLSFGFGGINTALVLER 410
|
|
| PKS |
cd00833 |
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different ... |
5-409 |
1.14e-73 |
|
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.
Pssm-ID: 238429 [Multi-domain] Cd Length: 421 Bit Score: 236.30 E-value: 1.14e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 5 RVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPIT--RFDASSFPTQIAA-------------EVRDFDP---------A 60
Cdd:cd00833 2 PIAIVGMACRFPGAADPDEFWENLLEGRDAISEIPedRWDADGYYPDPGKpgktytrrggfldDVDAFDAaffgispreA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 61 LVLDLksirktdvfvQF--AMESARQAWEDSGLEINETNAPRVGVAIGSGIGgmpwiekNYDALLTSGPRKISPFFIPGA 138
Cdd:cd00833 82 EAMDP----------QQrlLLEVAWEALEDAGYSPESLAGSRTGVFVGASSS-------DYLELLARDPDEIDAYAATGT 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 139 IINMASGMVSIKYDLKGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALStrndePEK 218
Cdd:cd00833 145 SRAFLANRISYFFDLRGPSLTVDTACSSSLVALHLACQSLRSGECDLALVGGVNLILSPDMFVGFSKAGMLS-----PDG 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 219 ASRPWDKGRDGFVLGEGAACVVVEELEHAKKRNATIYAEIIGFGMSGDAY--HMTRPDPEAegFTTCMKNSLRDAGIAPE 296
Cdd:cd00833 220 RCRPFDADADGYVRGEGVGVVVLKRLSDALRDGDRIYAVIRGSAVNQDGRtkGITAPSGEA--QAALIRRAYARAGVDPS 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 297 RVDYINAHGTSTPAADPLEARAIKKTFG---DHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPD 373
Cdd:cd00833 298 DIDYVEAHGTGTPLGDPIEVEALAKVFGgsrSADQPLLIGSVKSNIGHLEAAAGLAGLIKVVLALEHGVIPPNLHFETPN 377
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 29653839 374 EGCDLD----FVPNEAREMKIDTVMS----NSFGFGGTNGTLVL 409
Cdd:cd00833 378 PKIDFEesplRVPTEARPWPAPAGPRragvSSFGFGGTNAHVIL 421
|
|
| PRK09185 |
PRK09185 |
beta-ketoacyl-ACP synthase; |
6-411 |
1.99e-73 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 236398 [Multi-domain] Cd Length: 392 Bit Score: 234.74 E-value: 1.99e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 6 VVITGLGVVSPLGNKVSDMWQALLAGK-SGVKPITRFDASSfPTQIAAEVRDFDPALVLDLKSIR-KTDVFVQFAMESAR 83
Cdd:PRK09185 4 VYISAFGATSALGRGLDAILAALRAGRaSGMRPCDFWLVDL-PTWVGEVVGVELPALPAALAAFDcRNNRLALLALQQIE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 84 QAWEDSgleINETNAPRVGVAIG---SGIGGMpwiEKNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKGPNISI 160
Cdd:PRK09185 83 PAVEAA---IARYGADRIGVVLGtstSGILEG---ELAYRRRDPAHGALPADYHYAQQELGSLADFLRAYLGLSGPAYTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 161 VTACTTGLHNIGHAARMIAHNDADAMIAGGTE-MASTPLGigGFAAVRALSTRndepekASRPWDKGRDGFVLGEGAACV 239
Cdd:PRK09185 157 STACSSSAKVFASARRLLEAGLCDAAIVGGVDsLCRLTLN--GFNSLESLSPQ------PCRPFSANRDGINIGEAAAFF 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 240 VVEelehakkRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEARAI 319
Cdd:PRK09185 229 LLE-------REDDAAVALLGVGESSDAHHMSAPHPEGLGAILAMQQALADAGLAPADIGYINLHGTATPLNDAMESRAV 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 320 KKTFGDHaykLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEGCDLDFVPNEAREMKIDTVMSNSFG 399
Cdd:PRK09185 302 AAVFGDG---VPCSSTKGLTGHTLGAAGAVEAAICWLALRHGLPPHGWNTGQPDPALPPLYLVENAQALAIRYVLSNSFA 378
|
410
....*....|..
gi 29653839 400 FGGTNGTLVLSR 411
Cdd:PRK09185 379 FGGNNCSLIFGR 390
|
|
| ketoacyl-synt |
pfam00109 |
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
4-247 |
1.20e-68 |
|
Beta-ketoacyl synthase, N-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains. The N-terminal domain contains most of the structures involved in dimer formation and also the active site cysteine.
Pssm-ID: 425468 [Multi-domain] Cd Length: 251 Bit Score: 217.50 E-value: 1.20e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 4 RRVVITGLGVVSPLGNKVSDMWQALLAGKSGVKPI--TRFDASSF---PTQIAAEVR----------DFDPALV-LDLKS 67
Cdd:pfam00109 1 EPVAIVGMGCRFPGGNDPEEFWENLLEGRDGISEIpaDRWDPDKLydpPSRIAGKIYtkwgglddifDFDPLFFgISPRE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 68 IRKTDVFVQFAMESARQAWEDSGLEINETNAPRVGVAIGSGIGGmpwiEKNYDAL-LTSGPRKISPFFIpGAIINMASGM 146
Cdd:pfam00109 81 AERMDPQQRLLLEAAWEALEDAGITPDSLDGSRTGVFIGSGIGD----YAALLLLdEDGGPRRGSPFAV-GTMPSVIAGR 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 147 VSIKYDLKGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTrnDEPEKASRPWDkg 226
Cdd:pfam00109 156 ISYFLGLRGPSVTVDTACSSSLVAIHAAVQSIRSGEADVALAGGVNLLLTPLGFAGFSAAGMLSP--DGPCKAFDPFA-- 231
|
250 260
....*....|....*....|.
gi 29653839 227 rDGFVLGEGAACVVVEELEHA 247
Cdd:pfam00109 232 -DGFVRGEGVGAVVLKRLSDA 251
|
|
| decarbox_cond_enzymes |
cd00825 |
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new ... |
73-409 |
2.50e-68 |
|
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new carbon-carbon bond by a decarboxylating Claisen-like condensation reaction. Members are involved in the synthesis of fatty acids and polyketides, a diverse group of natural products. Both pathways are an iterative series of additions of small carbon units, usually acetate, to a nascent acyl group. There are 2 classes of decarboxylating condensing enzymes, which can be distinguished by sequence similarity, type of active site residues and type of primer units (acetyl CoA or acyl carrier protein (ACP) linked units).
Pssm-ID: 238421 [Multi-domain] Cd Length: 332 Bit Score: 219.81 E-value: 2.50e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 73 VFVQFAMESARQAWEDSGLEINETNAPRVGVAIGSGIGGMPWIEKNYDALLTSGPRKISPFFIPGAiinmaSGMVSIKYD 152
Cdd:cd00825 10 YVSILGFEAAERAIADAGLSREYQKNPIVGVVVGTGGGSPRFQVFGADAMRAVGPYVVTKAMFPGA-----SGQIATPLG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 153 LKGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPlgiggFAAVRALSTRNDEPEKASRPWDKGRDGFVL 232
Cdd:cd00825 85 IHGPAYDVSAACAGSLHALSLAADAVQNGKQDIVLAGGSEELAAP-----MDCEFDAMGALSTPEKASRTFDAAADGFVF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 233 GEGAACVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAAD 312
Cdd:cd00825 160 GDGAGALVVEELEHALARGAHIYAEIVGTAATIDGAGMGAFAPSAEGLARAAKEALAVAGLTVWDIDYLVAHGTGTPIGD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 313 PLEARAIKKTFGDHayKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENPDEgcDLDFVPNEAREMKIDT 392
Cdd:cd00825 240 VKELKLLRSEFGDK--SPAVSATKAMTGNLSSAAVVLAVDEAVLMLEHGFIPPSIHIEELDE--AGLNIVTETTPRELRT 315
|
330
....*....|....*..
gi 29653839 393 VMSNSFGFGGTNGTLVL 409
Cdd:cd00825 316 ALLNGFGLGGTNATLVL 332
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
23-409 |
5.15e-57 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 202.41 E-value: 5.15e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 23 DMWQALLAGKSGVKPIT--RFDASSF--PTQIAA------------EVRDFDP---------ALVLDlksirktdvfVQ- 76
Cdd:COG3321 23 EFWRNLRAGRDAITEVPadRWDADAYydPDPDAPgktyvrwggfldDVDEFDAlffgispreAEAMD----------PQq 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 77 -FAMESARQAWEDSGLEINETNAPRVGVAIGSGIGgmpwiekNYDALLTSGPRKISPFFIPGAIINMASGMVSIKYDLKG 155
Cdd:COG3321 93 rLLLEVAWEALEDAGYDPESLAGSRTGVFVGASSN-------DYALLLLADPEAIDAYALTGNAKSVLAGRISYKLDLRG 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 156 PNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALStrndePEKASRPWDKGRDGFVLGEG 235
Cdd:COG3321 166 PSVTVDTACSSSLVAVHLACQSLRSGECDLALAGGVNLMLTPESFILFSKGGMLS-----PDGRCRAFDADADGYVRGEG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 236 AACVVVEELEHAKKRNATIYAEIIGFGMS--GDAYHMTRPDPEAEgfTTCMKNSLRDAGIAPERVDYINAHGTSTPAADP 313
Cdd:COG3321 241 VGVVVLKRLSDALRDGDRIYAVIRGSAVNqdGRSNGLTAPNGPAQ--AAVIRRALADAGVDPATVDYVEAHGTGTPLGDP 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 314 LEARAIKKTFGDHAYK---LAVSSTKSMTGHMLGAAGALeTVI-SVLAIRDNTAPPTINLENPDEGCDLD----FVPNEA 385
Cdd:COG3321 319 IEAAALTAAFGQGRPAdqpCAIGSVKSNIGHLEAAAGVA-GLIkAVLALRHGVLPPTLHFETPNPHIDFEnspfYVNTEL 397
|
410 420 430
....*....|....*....|....*....|
gi 29653839 386 REMKIDT------VmsNSFGFGGTNGTLVL 409
Cdd:COG3321 398 RPWPAGGgprragV--SSFGFGGTNAHVVL 425
|
|
| Ketoacyl-synt_C |
pfam02801 |
Beta-ketoacyl synthase, C-terminal domain; The structure of beta-ketoacyl synthase is similar ... |
255-370 |
2.97e-47 |
|
Beta-ketoacyl synthase, C-terminal domain; The structure of beta-ketoacyl synthase is similar to that of the thiolase family (pfam00108) and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains.
Pssm-ID: 426989 Cd Length: 118 Bit Score: 157.73 E-value: 2.97e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 255 YAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEARAIKKTFGDHAYK--LAV 332
Cdd:pfam02801 1 YAVIKGSAVNHDGRHNGLTAPNGEGQARAIRRALADAGVDPEDVDYVEAHGTGTPLGDPIEAEALKRVFGSGARKqpLAI 80
|
90 100 110
....*....|....*....|....*....|....*...
gi 29653839 333 SSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLE 370
Cdd:pfam02801 81 GSVKSNIGHLEGAAGAAGLIKVVLALRHGVIPPTLNLE 118
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
77-409 |
4.31e-36 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 132.95 E-value: 4.31e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 77 FAMESARQAWEDSGLEinetNAPRVGVAIGSGIGGmpwieknyDALLTSGPRKISPFFIPGaiinmasgmvsikydlkGP 156
Cdd:cd00327 10 LGFEAAEQAIADAGLS----KGPIVGVIVGTTGGS--------GEFSGAAGQLAYHLGISG-----------------GP 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 157 NISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMastplgiggfaavralstrndepekasrpwdkgrdgFVLGEGA 236
Cdd:cd00327 61 AYSVNQACATGLTALALAVQQVQNGKADIVLAGGSEE------------------------------------FVFGDGA 104
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 237 ACVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMtRPDPEAEGFTTCMKNSLRDAGIAPERVDYINAHGTSTPAADPLEA 316
Cdd:cd00327 105 AAAVVESEEHALRRGAHPQAEIVSTAATFDGASM-VPAVSGEGLARAARKALEGAGLTPSDIDYVEAHGTGTPIGDAVEL 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 317 RAIKKTFGDHAykLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTinlenPDEGcdldfvpnearemkiDTVMSN 396
Cdd:cd00327 184 ALGLDPDGVRS--PAVSATLIMTGHPLGAAGLAILDELLLMLEHEFIPPT-----PREP---------------RTVLLL 241
|
330
....*....|...
gi 29653839 397 SFGFGGTNGTLVL 409
Cdd:cd00327 242 GFGLGGTNAAVVL 254
|
|
| omega_3_PfaA |
TIGR02813 |
polyketide-type polyunsaturated fatty acid synthase PfaA; Members of the seed for this ... |
136-409 |
2.26e-34 |
|
polyketide-type polyunsaturated fatty acid synthase PfaA; Members of the seed for this alignment are involved in omega-3 polyunsaturated fatty acid biosynthesis, such as the protein PfaA from the eicosapentaenoic acid biosynthesis operon in Photobacterium profundum strain SS9. PfaA is encoded together with PfaB, PfaC, and PfaD, and the functions of the individual polypeptides have not yet been described. More distant homologs of PfaA, also included with the reach of this model, appear to be involved in polyketide-like biosynthetic mechanisms of polyunsaturated fatty acid biosynthesis, an alternative to the more familiar iterated mechanism of chain extension and desaturation, and in most cases are encoded near genes for homologs of PfaB, PfaC, and/or PfaD.
Pssm-ID: 274311 [Multi-domain] Cd Length: 2582 Bit Score: 135.90 E-value: 2.26e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 136 PGAIINMASGMVSIKYDLKGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALSTRNDe 215
Cdd:TIGR02813 178 PGSLGNVISGRIANRFDLGGMNCVVDAACAGSLAAIRMALSELLEGRSEMMITGGVCTDNSPFMYMSFSKTPAFTTNED- 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 216 pekaSRPWDKGRDGFVLGEGAACVVVEELEHAKKRNATIYAEIIGFGMSGDAYHMTRPDPEAEGFTTCMKNSLRDAGIAP 295
Cdd:TIGR02813 257 ----IQPFDIDSKGMMIGEGIGMMALKRLEDAERDGDRIYAVIKGVGASSDGKFKSIYAPRPEGQAKALKRAYDDAGFAP 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 296 ERVDYINAHGTSTPAADPLEARAIKKTFG---DHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIRDNTAPPTINLENP 372
Cdd:TIGR02813 333 HTCGLIEAHGTGTAAGDVAEFGGLVSVFSqdnDQKQHIALGSVKSQIGHTKSTAGTAGMIKAVLALHHKVLPPTINVDQP 412
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 29653839 373 DEGCDLDFVP----NEARE--MKIDTVMS----NSFGFGGTNGTLVL 409
Cdd:TIGR02813 413 NPKLDIENSPfylnTETRPwmQREDGTPRragiSSFGFGGTNFHMVL 459
|
|
| PKS_KS |
smart00825 |
Beta-ketoacyl synthase; The structure of beta-ketoacyl synthase is similar to that of the ... |
6-409 |
2.13e-23 |
|
Beta-ketoacyl synthase; The structure of beta-ketoacyl synthase is similar to that of the thiolase family and also chalcone synthase. The active site of beta-ketoacyl synthase is located between the N and C-terminal domains.
Pssm-ID: 214836 [Multi-domain] Cd Length: 298 Bit Score: 99.33 E-value: 2.13e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 6 VVITGLGVVSPLGNKVSDMWQALLAGKSGVKpitRFDASSFptQI-AAEVRDFDPALVLdlksirktdvfvqfAMESARQ 84
Cdd:smart00825 1 IAIVGMSCRFPGADDPEEFWDLLLAGLDDVD---LFDAAFF--GIsPREAEAMDPQQRL--------------LLEVAWE 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 85 AWEDSGLEINETNAPRVGVAIGSGIGGmpwieknydalltsgprkispffipgaiinmasgmvsikYdlkgpNISIVTAC 164
Cdd:smart00825 62 ALEDAGIDPESLRGSRTGVFVGVSSSD---------------------------------------Y-----SVTVDTAC 97
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 165 TTGLHNIGHAARMIAHNDADAMIAGGTEMASTPLGIGGFAAVRALStrndePEKASRPWDKGRDGFVLGEGAACVVVEEL 244
Cdd:smart00825 98 SSSLVALHLACQSLRSGECDMALAGGVNLILSPDTFVGLSRAGMLS-----PDGRCKTFDASADGYVRGEGVGVVVLKRL 172
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 245 EHAKKRNATIYAEIIGFGM--SGDAYHMTRPDPEAEgfttcmknslrdagiapervdyinahgtstpaadplearaikkt 322
Cdd:smart00825 173 SDALRDGDPILAVIRGSAVnqDGRSNGITAPSGPAQ-------------------------------------------- 208
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 323 fgdhaykLAVSSTKSMTGHMLGAAGaLETVI-SVLAIRDNTAPPTINLENPDEGCDLD----FVPNEAREMKIDT----V 393
Cdd:smart00825 209 -------LLIGSVKSNIGHLEAAAG-VAGLIkVVLALKHGVIPPTLHFETPNPHIDLEesplRVPTELTPWPPPGrprrA 280
|
410
....*....|....*.
gi 29653839 394 MSNSFGFGGTNGTLVL 409
Cdd:smart00825 281 GVSSFGFGGTNAHVIL 296
|
|
| PRK06519 |
PRK06519 |
beta-ketoacyl-ACP synthase; |
1-365 |
7.95e-10 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235819 [Multi-domain] Cd Length: 398 Bit Score: 60.35 E-value: 7.95e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 1 MEKRRVVITGLGVVSPLGNKVSDMWQALLAGKsgvkPITRFDASSF---PTQIAAEVrDFDpalvldlKSI-RKTDvfvQ 76
Cdd:PRK06519 3 MQPNDVVITGIGLVSSLGEGLDAHWNALSAGR----PQPNVDTETFapyPVHPLPEI-DWS-------QQIpKRGD---Q 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 77 FAMES--------ARQAWEDSGLEINE--TNAPRVGVAIGSGiggmpwiEKNY--DALLTSGPRKISPffiPGAIINMA- 143
Cdd:PRK06519 68 RQMETwqrlgtyaAGLALDDAGIKGNEelLSTMDMIVAAGGG-------ERDIavDTAILNEARKRND---RGVLLNERl 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 144 -------------SGMvsikydLKGpNISIVTACT-----------TGLHNIGHAARMIAHNDADAMIAGGTEMASTPLG 199
Cdd:PRK06519 138 mtelrptlflaqlSNL------LAG-NISIVHKVTgssrtfmgeesAGVSAIEIAFARIASGQSDHALVGGAYNAERPDM 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 200 IGGFAAVRALSTRNDEPEKASRPWDKGrdGFVLGEGAACVVVEELEHAKKRNATIYAEIigfgmSGDAYHMTRPDPEAeg 279
Cdd:PRK06519 211 LLLYELGGLLLKGGWAPVWSRGGEDGG--GFILGSGGAFLVLESREHAEARGARPYARI-----SGVESDRARRAPGD-- 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 280 FTTCMKNSLRDAGIAPERVDYInahgTSTPAADPLEARaiKKTFGDHAYKLAVSSTKSMTGHMLGAAGALETVISVLAIR 359
Cdd:PRK06519 282 LEASLERLLKPAGGLAAPTAVI----SGATGAHPATAE--EKAALEAALAGPVRGIGTLFGHTMEAQFPLGLALAALSVS 355
|
....*.
gi 29653839 360 DNTAPP 365
Cdd:PRK06519 356 KGALFP 361
|
|
| PRK06147 |
PRK06147 |
3-oxoacyl-(acyl carrier protein) synthase; Validated |
167-301 |
2.59e-06 |
|
3-oxoacyl-(acyl carrier protein) synthase; Validated
Pssm-ID: 235715 [Multi-domain] Cd Length: 348 Bit Score: 48.86 E-value: 2.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 167 GLHNIGHAARMIAHNDADAMIAGGTE-MASTPLGIGGFAAVRALSTRNDEpekasrpwdkgrdGFVLGEGAACVVVEELE 245
Cdd:PRK06147 136 GAVALAQARRLIAAGGCPRVLVAGVDsLLTGPTLAHYEARDRLLTSQNSN-------------GFIPGEAAAAVLLGRPA 202
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 29653839 246 HAKKRNATIYAeiIGFGMSGDAYHMTRPDP-EAEGFTTCMKNSLRDAGIAPERVDYI 301
Cdd:PRK06147 203 GGEAPGLPLLG--LGLGREPAPVGESEDLPlRGDGLTQAIRAALAEAGCGLEDMDYR 257
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
74-304 |
1.21e-03 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 40.71 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 74 FVQFAMESARQAWEDSGLEINETNAPRVGVAIGSGIGGMPwieknydalltsgprkispffipGAIINMASGMvsikydL 153
Cdd:cd00829 16 PLELAAEAARAALDDAGLEPADIDAVVVGNAAGGRFQSFP-----------------------GALIAEYLGL------L 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 154 KGPNISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEMAST--------------------PLGIGGFAAVRAL---- 209
Cdd:cd00829 67 GKPATRVEAAGASGSAAVRAAAAAIASGLADVVLVVGAEKMSDvptgdeaggrasdlewegpePPGGLTPPALYALaarr 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 210 ----------------------STRND----------EPEKASRP-WD--KGRDGFVLGEGAACVVVEELEHAKKRNATi 254
Cdd:cd00829 147 ymhrygttredlakvavknhrnAARNPyaqfrkpitvEDVLNSRMiADplRLLDCCPVSDGAAAVVLASEERARELTDR- 225
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 29653839 255 YAEIIGFGMSGDAYHMTRPDPEA--EGFTTCMKNSLRDAGIAPERVDYINAH 304
Cdd:cd00829 226 PVWILGVGAASDTPSLSERDDFLslDAARLAARRAYKMAGITPDDIDVAELY 277
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
163-236 |
1.82e-03 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 40.05 E-value: 1.82e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 29653839 163 ACTTGLHNIGHAARMIAHNDADAMIAGGTEMAST-PLGIGGFAAVRALSTRNDEPEKASRPWDKgRDGFVLGEGA 236
Cdd:COG0183 87 VCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRaPMLLPKARWGYRMNAKLVDPMINPGLTDP-YTGLSMGETA 160
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
232-360 |
3.30e-03 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 39.31 E-value: 3.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 232 LGEGAACVVVEELEHAKKRNATIYAEIIGFgmsGDAYHmtrpDPEAegFTT----CMKNSLRDAGIAPERVDY--INahg 305
Cdd:PLN02644 250 ISDGAAALVLVSGEKALELGLQVIAKIRGY---ADAAQ----APEL--FTTapalAIPKALKHAGLEASQVDYyeIN--- 317
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 29653839 306 tstpAADPLEARAIKKTFGDHAYKLAVSSTKSMTGHMLGAAGA--LETVISVLAIRD 360
Cdd:PLN02644 318 ----EAFSVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGAriLVTLLGVLRSKN 370
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
69-202 |
3.56e-03 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 39.44 E-value: 3.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 69 RKTDVFVQ-FAMESARQAWEDSGLEINETNAPRVGVAIGSGIGGMPwieknydalltsgprkispffipGAIINMASGMV 147
Cdd:PRK12578 15 RRDDVSVQeLAWESIKEALNDAGVSQTDIELVVVGSTAYRGIELYP-----------------------APIVAEYSGLT 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 29653839 148 SikydlKGPnISIVTACTTGLHNIGHAARMIAHNDADAMIAGGTEM-----ASTPLGIGG 202
Cdd:PRK12578 72 G-----KVP-LRVEAMCATGLAASLTAYTAVASGLVDMAIAVGVDKmtevdTSTSLAIGG 125
|
|
| |
