3-octaprenyl-4-hydroxybenzoate carboxy-lyase; This family has been characterized as ...
6-436
0e+00
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; This family has been characterized as 3-octaprenyl-4- hydroxybenzoate carboxy-lyase enzymes. This enzyme catalyzes the third reaction in ubiquinone biosynthesis. For optimal activity the carboxy-lase was shown to require Mn2+.
The actual alignment was detected with superfamily member TIGR03701:
Pssm-ID: 444825 Cd Length: 433 Bit Score: 616.60 E-value: 0e+00
menaquinone biosynthesis decarboxylase, SCO4490 family; Members of this protein family are ...
6-436
0e+00
menaquinone biosynthesis decarboxylase, SCO4490 family; Members of this protein family are putative decarboxylases involved in a late stage of the alternative pathway for menaquinone, via futalosine, as in Streptomyces coelicolor and Helicobacter pylori. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 163413 Cd Length: 433 Bit Score: 616.60 E-value: 0e+00
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; This family has been characterized as ...
8-419
2.63e-147
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; This family has been characterized as 3-octaprenyl-4- hydroxybenzoate carboxy-lyase enzymes. This enzyme catalyzes the third reaction in ubiquinone biosynthesis. For optimal activity the carboxy-lase was shown to require Mn2+.
Pssm-ID: 426542 [Multi-domain] Cd Length: 401 Bit Score: 430.38 E-value: 2.63e-147
3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme transport and metabolism]; ...
3-438
5.61e-126
3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme transport and metabolism]; 3-polyprenyl-4-hydroxybenzoate decarboxylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 439813 Cd Length: 459 Bit Score: 377.93 E-value: 5.61e-126
menaquinone biosynthesis decarboxylase, SCO4490 family; Members of this protein family are ...
6-436
0e+00
menaquinone biosynthesis decarboxylase, SCO4490 family; Members of this protein family are putative decarboxylases involved in a late stage of the alternative pathway for menaquinone, via futalosine, as in Streptomyces coelicolor and Helicobacter pylori. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]
Pssm-ID: 163413 Cd Length: 433 Bit Score: 616.60 E-value: 0e+00
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; This family has been characterized as ...
8-419
2.63e-147
3-octaprenyl-4-hydroxybenzoate carboxy-lyase; This family has been characterized as 3-octaprenyl-4- hydroxybenzoate carboxy-lyase enzymes. This enzyme catalyzes the third reaction in ubiquinone biosynthesis. For optimal activity the carboxy-lase was shown to require Mn2+.
Pssm-ID: 426542 [Multi-domain] Cd Length: 401 Bit Score: 430.38 E-value: 2.63e-147
3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme transport and metabolism]; ...
3-438
5.61e-126
3-polyprenyl-4-hydroxybenzoate decarboxylase [Coenzyme transport and metabolism]; 3-polyprenyl-4-hydroxybenzoate decarboxylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 439813 Cd Length: 459 Bit Score: 377.93 E-value: 5.61e-126
UbiD family decarboxylase; The member of this family in E. coli is UbiD, ...
4-444
2.31e-103
UbiD family decarboxylase; The member of this family in E. coli is UbiD, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase. The family described by this model, however, is broad enough that it is likely to contain several different decarboxylases. Found in bacteria, archaea, and yeast, with two members in A. fulgidus. No homologs were detected besides those classified as orthologs. The member from H. pylori has a C-terminal extension of just over 100 residues that is shared in part by the Aquifex aeolicus homolog. [Unknown function, General]
Pssm-ID: 129252 Cd Length: 438 Bit Score: 318.94 E-value: 2.31e-103
phenylphosphate carboxylase, beta subunit; Members of this protein family are the beta subunit ...
4-361
1.51e-27
phenylphosphate carboxylase, beta subunit; Members of this protein family are the beta subunit of phenylphosphate carboxylase. Phenol (methyl-benzene) is converted to phenylphosphate, then para-carboxylated by this four-subunit enzyme, with the release of phosphate, to 4-hydroxybenzoate. The enzyme contains neither biotin nor thiamin pyrophosphate. This beta subunit is homologous to the alpha subunit and, more broadly, to UbiD family decarboxylases.
Pssm-ID: 131771 [Multi-domain] Cd Length: 472 Bit Score: 115.96 E-value: 1.51e-27
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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This image shows a graphical summary of conserved domains identified on the query sequence.
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if a domain or superfamily has been annotated with functional sites (conserved features),
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The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
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(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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