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Concise Results
Standard Results
Full Results
beta-lactamase class C, partial [Klebsiella pneumoniae]
Protein Classification
beta-lactamase ( domain architecture ID 10013775 )
beta-lactamase, belonging to the class C family, catalyzes the hydrolysis of beta-lactams such as cephalosporins
List of domain hits
Name
Accession
Description
Interval
E-value
ampC
PRK11289 beta-lactamase/D-alanine carboxypeptidase; Provisional
1-381
0e+00
beta-lactamase/D-alanine carboxypeptidase; Provisional
Pssm-ID: 236894
Cd Length: 384
Bit Score: 631.16
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 1 MM KKS L CC ALLLTAS F S T FAAA K T E QQ IA DIV N RTITPLM Q EQ A IPGMAVAVIY Q GKPYYF TW G K AD I A NNH PVTQ Q TLF 80
Cdd:PRK11289 4 MM LLL L LA ALLLTAS A S A FAAA A T P QQ LK DIV D RTITPLM E EQ D IPGMAVAVIY N GKPYYF NY G V AD K A TGQ PVTQ D TLF 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 81 ELGSVSKTF NGV L G G D A I ARGE IK LSDP VT KY W PEL T G KQWQ GI R LLHLATYTAGGLPLQ I PD D V R D K A A LL HFY Q N WQP 160
Cdd:PRK11289 84 ELGSVSKTF TAT L A G Y A Q ARGE LS LSDP AS KY L PEL K G SPFD GI T LLHLATYTAGGLPLQ V PD E V K D D A Q LL RYF Q A WQP 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 161 QWT PG AK RLY A N S SIGLFG A LA V K PS G MSY E EA M TR R VLQ PL K L A HT W I T VP QN E QK DYA R GY - R EGKPV H V S PG Q LDAE 239
Cdd:PRK11289 164 AYA PG TQ RLY S N P SIGLFG Y LA A K AM G QPF E QL M EQ R LFP PL G L T HT Y I N VP EA E MA DYA Q GY n K EGKPV R V N PG V LDAE 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 240 AYGVKS SVI DM A R W VQAN MDASHV q EK TLQQ G I A L A Q SR Y W R I GDM Y QGLGWEM LNW P LKA D SIIN G SDS K V AL AAL P AV 319
Cdd:PRK11289 244 AYGVKS TAA DM L R F VQAN LGPQDL - DP TLQQ A I Q L T Q TG Y F R V GDM T QGLGWEM YPY P VSL D TLLA G NSN K M AL EPQ P VT 322
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2959382 320 EVN PP A P A V K A S W VH KTGST G GFG S YVAFVP E K N LGIVMLANK S YPNP V RV E AA WR IL EK L Q 381
Cdd:PRK11289 323 AIT PP Q P P V R A V W IN KTGST N GFG A YVAFVP A K R LGIVMLANK N YPNP A RV K AA YQ IL NA L A 384
Name
Accession
Description
Interval
E-value
ampC
PRK11289 beta-lactamase/D-alanine carboxypeptidase; Provisional
1-381
0e+00
beta-lactamase/D-alanine carboxypeptidase; Provisional
Pssm-ID: 236894
Cd Length: 384
Bit Score: 631.16
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 1 MM KKS L CC ALLLTAS F S T FAAA K T E QQ IA DIV N RTITPLM Q EQ A IPGMAVAVIY Q GKPYYF TW G K AD I A NNH PVTQ Q TLF 80
Cdd:PRK11289 4 MM LLL L LA ALLLTAS A S A FAAA A T P QQ LK DIV D RTITPLM E EQ D IPGMAVAVIY N GKPYYF NY G V AD K A TGQ PVTQ D TLF 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 81 ELGSVSKTF NGV L G G D A I ARGE IK LSDP VT KY W PEL T G KQWQ GI R LLHLATYTAGGLPLQ I PD D V R D K A A LL HFY Q N WQP 160
Cdd:PRK11289 84 ELGSVSKTF TAT L A G Y A Q ARGE LS LSDP AS KY L PEL K G SPFD GI T LLHLATYTAGGLPLQ V PD E V K D D A Q LL RYF Q A WQP 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 161 QWT PG AK RLY A N S SIGLFG A LA V K PS G MSY E EA M TR R VLQ PL K L A HT W I T VP QN E QK DYA R GY - R EGKPV H V S PG Q LDAE 239
Cdd:PRK11289 164 AYA PG TQ RLY S N P SIGLFG Y LA A K AM G QPF E QL M EQ R LFP PL G L T HT Y I N VP EA E MA DYA Q GY n K EGKPV R V N PG V LDAE 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 240 AYGVKS SVI DM A R W VQAN MDASHV q EK TLQQ G I A L A Q SR Y W R I GDM Y QGLGWEM LNW P LKA D SIIN G SDS K V AL AAL P AV 319
Cdd:PRK11289 244 AYGVKS TAA DM L R F VQAN LGPQDL - DP TLQQ A I Q L T Q TG Y F R V GDM T QGLGWEM YPY P VSL D TLLA G NSN K M AL EPQ P VT 322
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2959382 320 EVN PP A P A V K A S W VH KTGST G GFG S YVAFVP E K N LGIVMLANK S YPNP V RV E AA WR IL EK L Q 381
Cdd:PRK11289 323 AIT PP Q P P V R A V W IN KTGST N GFG A YVAFVP A K R LGIVMLANK N YPNP A RV K AA YQ IL NA L A 384
ampC_Kaer
NF041662 CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This narrowly defined ...
1-381
0e+00
CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This narrowly defined subfamily of AmpC class C beta-lactamases covers chromosomal ly encoded proteins apparently restricted to and universal in Klebsiella (previously Enterobacter) aerogenes. Strains encoding this enzyme tend to be resistant to penicillins and first and second generation cephalosporins.
Pssm-ID: 469544
Cd Length: 381
Bit Score: 622.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 1 MMKKSL CCA LLL T ASFSTFAA AK T EQ Q IADI VN R TITPLM Q EQAIPGMAVAVIY Q GKPYYFTWG K AD I A NNH PVT Q QTLF 80
Cdd:NF041662 1 MMKKSL TGV LLL G ASFSTFAA PQ T AE Q LREL VN Q TITPLM K EQAIPGMAVAVIY H GKPYYFTWG Q AD V A GQR PVT R QTLF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 81 ELGSVSKTF N GVLGGDA I ARGEIKLSDP VT KYWP E LTG K QWQGI R LLHLATYTAGGLPLQ I PD D V R D K AALL HF YQNWQP 160
Cdd:NF041662 81 ELGSVSKTF T GVLGGDA V ARGEIKLSDP AQ KYWP Q LTG Q QWQGI S LLHLATYTAGGLPLQ V PD E V T D E AALL RY YQNWQP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 161 QW T PG A KRLYAN S SIGLFGALAVKPSGMS Y E E AM TR RVLQPLKL A HTWI T VP QNEQ KDYA R GYR E GK P VHVSPGQLDAEA 240
Cdd:NF041662 161 QW A PG S KRLYAN A SIGLFGALAVKPSGMS F E Q AM SQ RVLQPLKL S HTWI N VP PAQS KDYA W GYR D GK A VHVSPGQLDAEA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 241 YGVKSS VI DMA R WV Q ANM DASH VQ E K T L Q QGI A LAQSRYWR I G D MYQGLGWEMLNWP LK A DSI INGSD S KVALAA L P AVE 320
Cdd:NF041662 241 YGVKSS IE DMA H WV L ANM NREA VQ D K N L R QGI Q LAQSRYWR A G E MYQGLGWEMLNWP VS A EVL INGSD N KVALAA T P VTA 320
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2959382 321 VNPPAP A VKASWVHKTGSTGGFGSYVAF V P EKN LGIVMLANKSYPNP V RV E AA WR ILE K LQ 381
Cdd:NF041662 321 VNPPAP P VKASWVHKTGSTGGFGSYVAF I P QQD LGIVMLANKSYPNP E RV K AA YH ILE A LQ 381
ampC_Ecan
NF041666 CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This HMM identifies a ...
1-381
0e+00
CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This HMM identifies a small subset of chromosomal class C beta-lactamases (AmpC) typical of Enterobacter cancerogenus.
Pssm-ID: 469548
Cd Length: 381
Bit Score: 598.30
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 1 M M KK SLC CALLL TA S F S TF A AAKT E QQI A DI V N RT I TPLM QE Q A IPGMAVAVIYQG K P Y YFT W GKAD I A N N H PVT Q QTLF 80
Cdd:NF041666 1 M K KK LVF CALLL GV S C S AL A SSLS E KEL A KV V K RT V TPLM KA Q S IPGMAVAVIYQG Q P H YFT F GKAD V A A N I PVT P QTLF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 81 ELGSVSKTF N GVLGGDAIARGEI K L S DPVT K YWPELTGKQWQGIRLL H LATYTAGGLPLQ I PD D V R D K AALL H FYQ N WQP 160
Cdd:NF041666 81 ELGSVSKTF T GVLGGDAIARGEI S L N DPVT R YWPELTGKQWQGIRLL D LATYTAGGLPLQ V PD N V T D P AALL N FYQ T WQP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 161 QW T PG AK RLYANSSIGLFGALAVKPSGM SY E E AMT R RVL Q PLKL A HTWI TV P QN E QKD YA R GYR E GK P VHVSPG Q LD A EA 240
Cdd:NF041666 161 QW K PG TT RLYANSSIGLFGALAVKPSGM GF E Q AMT T RVL K PLKL D HTWI QI P KS E EQH YA W GYR D GK A VHVSPG M LD G EA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 241 YGVKS SVI DMA R WV QA NM DASH VQ EKT L Q QGIALAQSRYWR I G D MYQGLGWEMLNWP LKADS II N GSD S K V ALAALPA V E 320
Cdd:NF041666 241 YGVKS NAE DMA S WV MV NM ALER VQ ATS L K QGIALAQSRYWR V G S MYQGLGWEMLNWP VDGKT II D GSD N K I ALAALPA R E 320
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2959382 321 VNPPAP A VKASWVHKTGSTGGFGSYVAF V PEK N LGIVMLANKSYPNP V RVEAA WR IL EK LQ 381
Cdd:NF041666 321 VNPPAP P VKASWVHKTGSTGGFGSYVAF I PEK Q LGIVMLANKSYPNP A RVEAA YQ IL NA LQ 381
Beta-lactamase
pfam00144 Beta-lactamase; This family appears to be distantly related to pfam00905 and PF00768 ...
32-381
1.91e-98
Beta-lactamase; This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.
Pssm-ID: 395092 [Multi-domain]
Cd Length: 327
Bit Score: 295.57
E-value: 1.91e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 32 VN R T I TP LM QEQA IPG M AVAV IYQ GK PYYFTW - G K AD IANNH PVT QQ TLF ELG SV S KTF NGVLGGDAIA RG EIK L S DPV T 110
Cdd:pfam00144 1 LD R L I RE LM AQGG IPG V AVAV TRD GK VVVDRG g G V AD LEGGR PVT AD TLF RIA SV T KTF TAAAVLQLVE RG KLD L D DPV S 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 111 KY W PE LT G KQWQ GI R L LH L A T Y T A G GL PL QI PDD V ---- R D K A A L LHFYQNWQ P Q W T PG AKRL Y A N SSI GL F G A L AVKPS 186
Cdd:pfam00144 81 KY L PE FA G PGKG GI T L RD L L T H T S G LP PL FA PDD L eeaa A D A A E L VRALAALP P V W P PG TRWG Y S N TAY GL L G E L LERVT 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 187 G M SYEE AMTR R V L Q PL KLAH T WIT VP QNEQKDY A R GY - R EG K PV H V S PG Q L D A E AY - G V KS SVI D M AR WVQ A NMDASHVQ 264
Cdd:pfam00144 161 G Q SYEE LLGD R I L R PL GMTD T ELG VP EPGDPRD A A GY t G EG P PV R V P PG P L P A G AY g G L KS TAR D L AR FLL A LLGGLLLS 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 265 EKT L Q Q GIALAQSRYWRI G DMYQ GLG wem L N W P L K adsiingsdskvalaalpavevnp PAPAVKASWVHK tgs TGG F G S 344
Cdd:pfam00144 241 AAA L A Q LTDWLRGGTTGV G GIRA GLG --- L G W V L A ------------------------ DKTGAGPGLFGH --- TGG Y G T 290
330 340 350
....*....|....*....|....*....|....*..
gi 2959382 345 Y V A FV P EKN L GI V M L A N KSY PNP VRV E A A WR I LEKLQ 381
Cdd:pfam00144 291 Y L A VD P DIG L VV V V L S N RLG PNP DAA E D A RL I ALAAA 327
AmpC
COG1680 CubicO group peptidase, beta-lactamase class C family [Defense mechanisms];
16-377
2.74e-73
CubicO group peptidase, beta-lactamase class C family [Defense mechanisms];
Pssm-ID: 441286 [Multi-domain]
Cd Length: 355
Bit Score: 231.88
E-value: 2.74e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 16 F STF A A A KTEQQIADIVNRTITPLMQ E QA IPG M AVAV IYQ GK PY Y F - TW G K AD IANNH PVT QQ TLF ELG SV S K T F NGVLG 94
Cdd:COG1680 3 F AAA A P A AGLSADLAALDAALDAALA E GG IPG A AVAV VRD GK VV Y E k AY G V AD LETGR PVT PD TLF RIA SV T K S F TATAV 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 95 GDAIAR G EIK L S DPV T KY W PE LTGK -- QWQG I RLL HL A T Y T A G g LP LQI PD DVRD -------- KAA LL HFYQNWQPQWT P 164
Cdd:COG1680 83 LQLVEE G KLD L D DPV S KY L PE FKLP dd AKRD I TVR HL L T H T S G - LP DYE PD PYDA advarpyt PDD LL ARLAALPLLFE P 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 165 G AKRL Y A N SSIG L F G ALAVKPS G MSY E EAMTR R VLQ PL KLAH T WITV P QN E QKDY A R GY REGKP VH VS P GQ L D A E -- A Y G 242
Cdd:COG1680 162 G TRFS Y S N LGYD L L G EIIERVT G QPL E DYLRE R IFE PL GMTD T GFGL P DA E AARL A P GY EADGE VH DA P AW L G A V ag A G G 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 243 VK S SVI D M AR WV QA NMDASHVQE K T L -- QQGI A LAQSRYWRI GD -- MYQ GLGW EMLNW plkadsii N GS D skvalaalpa 318
Cdd:COG1680 242 LF S TAR D L AR FG QA LLNGGEWDG K R L ls PETL A EMTTPQVPS GD ag GGY GLGW WLNDD -------- G GS G ---------- 303
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2959382 319 vevnppapavkas WVHKT G S T G GF GSYVAFV PE KN LG I V M L A N KSY P NPVRVE A AWRI L 377
Cdd:COG1680 304 ------------- SFGHG G A T P GF STFLWVD PE RG LG V V V L T N RDD P GAGDRA A LLEA L 349
Name
Accession
Description
Interval
E-value
ampC
PRK11289 beta-lactamase/D-alanine carboxypeptidase; Provisional
1-381
0e+00
beta-lactamase/D-alanine carboxypeptidase; Provisional
Pssm-ID: 236894
Cd Length: 384
Bit Score: 631.16
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 1 MM KKS L CC ALLLTAS F S T FAAA K T E QQ IA DIV N RTITPLM Q EQ A IPGMAVAVIY Q GKPYYF TW G K AD I A NNH PVTQ Q TLF 80
Cdd:PRK11289 4 MM LLL L LA ALLLTAS A S A FAAA A T P QQ LK DIV D RTITPLM E EQ D IPGMAVAVIY N GKPYYF NY G V AD K A TGQ PVTQ D TLF 83
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 81 ELGSVSKTF NGV L G G D A I ARGE IK LSDP VT KY W PEL T G KQWQ GI R LLHLATYTAGGLPLQ I PD D V R D K A A LL HFY Q N WQP 160
Cdd:PRK11289 84 ELGSVSKTF TAT L A G Y A Q ARGE LS LSDP AS KY L PEL K G SPFD GI T LLHLATYTAGGLPLQ V PD E V K D D A Q LL RYF Q A WQP 163
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 161 QWT PG AK RLY A N S SIGLFG A LA V K PS G MSY E EA M TR R VLQ PL K L A HT W I T VP QN E QK DYA R GY - R EGKPV H V S PG Q LDAE 239
Cdd:PRK11289 164 AYA PG TQ RLY S N P SIGLFG Y LA A K AM G QPF E QL M EQ R LFP PL G L T HT Y I N VP EA E MA DYA Q GY n K EGKPV R V N PG V LDAE 243
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 240 AYGVKS SVI DM A R W VQAN MDASHV q EK TLQQ G I A L A Q SR Y W R I GDM Y QGLGWEM LNW P LKA D SIIN G SDS K V AL AAL P AV 319
Cdd:PRK11289 244 AYGVKS TAA DM L R F VQAN LGPQDL - DP TLQQ A I Q L T Q TG Y F R V GDM T QGLGWEM YPY P VSL D TLLA G NSN K M AL EPQ P VT 322
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2959382 320 EVN PP A P A V K A S W VH KTGST G GFG S YVAFVP E K N LGIVMLANK S YPNP V RV E AA WR IL EK L Q 381
Cdd:PRK11289 323 AIT PP Q P P V R A V W IN KTGST N GFG A YVAFVP A K R LGIVMLANK N YPNP A RV K AA YQ IL NA L A 384
ampC_Kaer
NF041662 CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This narrowly defined ...
1-381
0e+00
CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This narrowly defined subfamily of AmpC class C beta-lactamases covers chromosomal ly encoded proteins apparently restricted to and universal in Klebsiella (previously Enterobacter) aerogenes. Strains encoding this enzyme tend to be resistant to penicillins and first and second generation cephalosporins.
Pssm-ID: 469544
Cd Length: 381
Bit Score: 622.97
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 1 MMKKSL CCA LLL T ASFSTFAA AK T EQ Q IADI VN R TITPLM Q EQAIPGMAVAVIY Q GKPYYFTWG K AD I A NNH PVT Q QTLF 80
Cdd:NF041662 1 MMKKSL TGV LLL G ASFSTFAA PQ T AE Q LREL VN Q TITPLM K EQAIPGMAVAVIY H GKPYYFTWG Q AD V A GQR PVT R QTLF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 81 ELGSVSKTF N GVLGGDA I ARGEIKLSDP VT KYWP E LTG K QWQGI R LLHLATYTAGGLPLQ I PD D V R D K AALL HF YQNWQP 160
Cdd:NF041662 81 ELGSVSKTF T GVLGGDA V ARGEIKLSDP AQ KYWP Q LTG Q QWQGI S LLHLATYTAGGLPLQ V PD E V T D E AALL RY YQNWQP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 161 QW T PG A KRLYAN S SIGLFGALAVKPSGMS Y E E AM TR RVLQPLKL A HTWI T VP QNEQ KDYA R GYR E GK P VHVSPGQLDAEA 240
Cdd:NF041662 161 QW A PG S KRLYAN A SIGLFGALAVKPSGMS F E Q AM SQ RVLQPLKL S HTWI N VP PAQS KDYA W GYR D GK A VHVSPGQLDAEA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 241 YGVKSS VI DMA R WV Q ANM DASH VQ E K T L Q QGI A LAQSRYWR I G D MYQGLGWEMLNWP LK A DSI INGSD S KVALAA L P AVE 320
Cdd:NF041662 241 YGVKSS IE DMA H WV L ANM NREA VQ D K N L R QGI Q LAQSRYWR A G E MYQGLGWEMLNWP VS A EVL INGSD N KVALAA T P VTA 320
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2959382 321 VNPPAP A VKASWVHKTGSTGGFGSYVAF V P EKN LGIVMLANKSYPNP V RV E AA WR ILE K LQ 381
Cdd:NF041662 321 VNPPAP P VKASWVHKTGSTGGFGSYVAF I P QQD LGIVMLANKSYPNP E RV K AA YH ILE A LQ 381
ampC_Ecan
NF041666 CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This HMM identifies a ...
1-381
0e+00
CMY2-MIR-ACT-EC family cephalosporin-hydrolyzing class C beta-lactamase; This HMM identifies a small subset of chromosomal class C beta-lactamases (AmpC) typical of Enterobacter cancerogenus.
Pssm-ID: 469548
Cd Length: 381
Bit Score: 598.30
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 1 M M KK SLC CALLL TA S F S TF A AAKT E QQI A DI V N RT I TPLM QE Q A IPGMAVAVIYQG K P Y YFT W GKAD I A N N H PVT Q QTLF 80
Cdd:NF041666 1 M K KK LVF CALLL GV S C S AL A SSLS E KEL A KV V K RT V TPLM KA Q S IPGMAVAVIYQG Q P H YFT F GKAD V A A N I PVT P QTLF 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 81 ELGSVSKTF N GVLGGDAIARGEI K L S DPVT K YWPELTGKQWQGIRLL H LATYTAGGLPLQ I PD D V R D K AALL H FYQ N WQP 160
Cdd:NF041666 81 ELGSVSKTF T GVLGGDAIARGEI S L N DPVT R YWPELTGKQWQGIRLL D LATYTAGGLPLQ V PD N V T D P AALL N FYQ T WQP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 161 QW T PG AK RLYANSSIGLFGALAVKPSGM SY E E AMT R RVL Q PLKL A HTWI TV P QN E QKD YA R GYR E GK P VHVSPG Q LD A EA 240
Cdd:NF041666 161 QW K PG TT RLYANSSIGLFGALAVKPSGM GF E Q AMT T RVL K PLKL D HTWI QI P KS E EQH YA W GYR D GK A VHVSPG M LD G EA 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 241 YGVKS SVI DMA R WV QA NM DASH VQ EKT L Q QGIALAQSRYWR I G D MYQGLGWEMLNWP LKADS II N GSD S K V ALAALPA V E 320
Cdd:NF041666 241 YGVKS NAE DMA S WV MV NM ALER VQ ATS L K QGIALAQSRYWR V G S MYQGLGWEMLNWP VDGKT II D GSD N K I ALAALPA R E 320
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2959382 321 VNPPAP A VKASWVHKTGSTGGFGSYVAF V PEK N LGIVMLANKSYPNP V RVEAA WR IL EK LQ 381
Cdd:NF041666 321 VNPPAP P VKASWVHKTGSTGGFGSYVAF I PEK Q LGIVMLANKSYPNP A RVEAA YQ IL NA LQ 381
Beta-lactamase
pfam00144 Beta-lactamase; This family appears to be distantly related to pfam00905 and PF00768 ...
32-381
1.91e-98
Beta-lactamase; This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.
Pssm-ID: 395092 [Multi-domain]
Cd Length: 327
Bit Score: 295.57
E-value: 1.91e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 32 VN R T I TP LM QEQA IPG M AVAV IYQ GK PYYFTW - G K AD IANNH PVT QQ TLF ELG SV S KTF NGVLGGDAIA RG EIK L S DPV T 110
Cdd:pfam00144 1 LD R L I RE LM AQGG IPG V AVAV TRD GK VVVDRG g G V AD LEGGR PVT AD TLF RIA SV T KTF TAAAVLQLVE RG KLD L D DPV S 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 111 KY W PE LT G KQWQ GI R L LH L A T Y T A G GL PL QI PDD V ---- R D K A A L LHFYQNWQ P Q W T PG AKRL Y A N SSI GL F G A L AVKPS 186
Cdd:pfam00144 81 KY L PE FA G PGKG GI T L RD L L T H T S G LP PL FA PDD L eeaa A D A A E L VRALAALP P V W P PG TRWG Y S N TAY GL L G E L LERVT 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 187 G M SYEE AMTR R V L Q PL KLAH T WIT VP QNEQKDY A R GY - R EG K PV H V S PG Q L D A E AY - G V KS SVI D M AR WVQ A NMDASHVQ 264
Cdd:pfam00144 161 G Q SYEE LLGD R I L R PL GMTD T ELG VP EPGDPRD A A GY t G EG P PV R V P PG P L P A G AY g G L KS TAR D L AR FLL A LLGGLLLS 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 265 EKT L Q Q GIALAQSRYWRI G DMYQ GLG wem L N W P L K adsiingsdskvalaalpavevnp PAPAVKASWVHK tgs TGG F G S 344
Cdd:pfam00144 241 AAA L A Q LTDWLRGGTTGV G GIRA GLG --- L G W V L A ------------------------ DKTGAGPGLFGH --- TGG Y G T 290
330 340 350
....*....|....*....|....*....|....*..
gi 2959382 345 Y V A FV P EKN L GI V M L A N KSY PNP VRV E A A WR I LEKLQ 381
Cdd:pfam00144 291 Y L A VD P DIG L VV V V L S N RLG PNP DAA E D A RL I ALAAA 327
AmpC
COG1680 CubicO group peptidase, beta-lactamase class C family [Defense mechanisms];
16-377
2.74e-73
CubicO group peptidase, beta-lactamase class C family [Defense mechanisms];
Pssm-ID: 441286 [Multi-domain]
Cd Length: 355
Bit Score: 231.88
E-value: 2.74e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 16 F STF A A A KTEQQIADIVNRTITPLMQ E QA IPG M AVAV IYQ GK PY Y F - TW G K AD IANNH PVT QQ TLF ELG SV S K T F NGVLG 94
Cdd:COG1680 3 F AAA A P A AGLSADLAALDAALDAALA E GG IPG A AVAV VRD GK VV Y E k AY G V AD LETGR PVT PD TLF RIA SV T K S F TATAV 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 95 GDAIAR G EIK L S DPV T KY W PE LTGK -- QWQG I RLL HL A T Y T A G g LP LQI PD DVRD -------- KAA LL HFYQNWQPQWT P 164
Cdd:COG1680 83 LQLVEE G KLD L D DPV S KY L PE FKLP dd AKRD I TVR HL L T H T S G - LP DYE PD PYDA advarpyt PDD LL ARLAALPLLFE P 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 165 G AKRL Y A N SSIG L F G ALAVKPS G MSY E EAMTR R VLQ PL KLAH T WITV P QN E QKDY A R GY REGKP VH VS P GQ L D A E -- A Y G 242
Cdd:COG1680 162 G TRFS Y S N LGYD L L G EIIERVT G QPL E DYLRE R IFE PL GMTD T GFGL P DA E AARL A P GY EADGE VH DA P AW L G A V ag A G G 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 243 VK S SVI D M AR WV QA NMDASHVQE K T L -- QQGI A LAQSRYWRI GD -- MYQ GLGW EMLNW plkadsii N GS D skvalaalpa 318
Cdd:COG1680 242 LF S TAR D L AR FG QA LLNGGEWDG K R L ls PETL A EMTTPQVPS GD ag GGY GLGW WLNDD -------- G GS G ---------- 303
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 2959382 319 vevnppapavkas WVHKT G S T G GF GSYVAFV PE KN LG I V M L A N KSY P NPVRVE A AWRI L 377
Cdd:COG1680 304 ------------- SFGHG G A T P GF STFLWVD PE RG LG V V V L T N RDD P GAGDRA A LLEA L 349
PRK10662
PRK10662 beta-lactam binding protein AmpH; Provisional
1-363
1.65e-31
beta-lactam binding protein AmpH; Provisional
Pssm-ID: 236732 [Multi-domain]
Cd Length: 378
Bit Score: 122.83
E-value: 1.65e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 1 M MKKS L CC A L L LT A SFSTFA AA KT --- EQQIA DIV N R TITPLMQEQAIP GMA VA VI YQGKPYYFTW G KADIA NN HPVTQQ 77
Cdd:PRK10662 1 M KRSL L FS A A L CA A ALTSAH AA QP aad PLLAS DIV D R YAEHIFYGSGAT GMA LV VI DGNQRVFRSY G ETRPG NN VRPQLD 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 78 T L FELG S VS K TFNGVLGGDAIAR G EI KL S DP VT KY W P --- ELTGKQW Q G I R LL H LAT Y T AG g LP LQI P -- DDV R DKAALL 152
Cdd:PRK10662 81 S L IRIA S IT K LMTSEVLVKLADD G TV KL T DP LS KY A P pga RVPTYNG Q P I T LL N LAT H T SA - LP REQ P gg AAH R PVFVWP 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 153 HFY Q N W Q ------ PQWT PG AKRL Y A N SSIG L FG - ALA v K PS G MS Y EEAMTRRVLQ PL KLAH T WI T v P QNE Q K dy AR --- G 222
Cdd:PRK10662 160 TRE Q R W K wlstak LKAA PG TQAA Y S N LAFD L LA d ALA - K AA G KP Y TQLLREKITR PL GMKD T TF T - P SPD Q C -- AR lmv G 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 223 YREGK P VHVSPG ql DAEAY GV K S SVI DM A RW V Q ANMD a S HVQEKTL Q qg IALA Q SRYWRIGDMYQGL G WEM lnw P L KAD S 302
Cdd:PRK10662 236 EKGAS P CNNTLA -- AIGSG GV Y S TPG DM M RW M Q QFLS - S DNYQRSQ Q -- ADRM Q TLIYQRAQLTSVI G MDV --- P G KAD A 307
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2959382 303 IIN G S dsk V AL A ALPAV evnppa P AV kasw VH KTG ST GGF GS Y V A FV P EK N L G IVMLANK S 363
Cdd:PRK10662 308 LGL G W --- V YM A PKDGR ------ P GI ---- IQ KTG GG GGF IT Y M A MI P QR N I G VFVVVTR S 355
PRK13128
PRK13128 D-aminopeptidase; Reviewed
46-277
3.05e-06
D-aminopeptidase; Reviewed
Pssm-ID: 171868 [Multi-domain]
Cd Length: 518
Bit Score: 49.08
E-value: 3.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 46 PG M AVAV IYQ G KPYY - FT WG K AD I A NNHPV T QQ T LFELG SVSK T F N - G VL g G D A I ARG E I k L SDPVTK Y WPELTGKQ --- 120
Cdd:PRK13128 23 PG G AVAV VKD G EVVL r HA WG F AD L A RRKAM T PE T RMPIC SVSK Q F T c A VL - L D C I GEP E M - L DAALAA Y LDQFEDPR pav 100
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 121 ------ WQ G I R LLHLA T YTA G GL P LQ I -- PD DVR --- DKAALL HF yqnwqpqw T PG AKRL Y A N SSIGLFGA L AVKPS G M S 189
Cdd:PRK13128 101 rdlcnn QS G L R DYWAL T VLC G AA P EG I fl PD QAQ nll RRLKTT HF -------- A PG THYS Y C N GNFRILAD L IEQHT G R S 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 190 YEEAMTR R VLQ P LKL a H T WITV P QNEQK D YAR GY r EG KP V H vsp G Q L D A EA ------- Y G VKS S VI DM AR W V Q A n M D ASH 262
Cdd:PRK13128 173 LADLLAE R IFA P AGM - K T AELI P DTALF D ECT GY - EG DT V R --- G F L P A IN rihwlgd A G ICA S LD DM IA W E Q F - I D RTR 246
250
....*....|....*
gi 2959382 263 VQ E KT L QQGIALA Q S 277
Cdd:PRK13128 247 DD E NG L YRRLSVP Q T 261
PRK03642
PRK03642 putative periplasmic esterase; Provisional
2-368
3.49e-05
putative periplasmic esterase; Provisional
Pssm-ID: 179620 [Multi-domain]
Cd Length: 432
Bit Score: 45.55
E-value: 3.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 2 MK KS L CCAL LL TA S F S TF AA ------- A KT E QQIADIVNRTITPLMQE Q A I ---- PG MAVAV I YQGKPY Y F - T WG K A --- 66
Cdd:PRK03642 1 MK RT L LYTS LL AF S C S AS AA kypvlte A SP E KAGFNSEKLNQMDRWIS Q Q I dagy PG VNLLI I KDNQIV Y R k A WG Y A kky 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 67 -- DIANN HPV -- T QQ T LFE L G S VS K TF -- N GV L G g DAIAR G EIKLS D PVT KY W P E -------- LT GK - QWQG I R LLH lat 131
Cdd:PRK03642 81 dg STLLA HPV ka T TN T MYD L A S NT K MY at N FA L Q - KLVSE G KLDVN D LIS KY I P G fkdspgdk IK GK n TLRI I D LLH --- 156
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 132 y TAG G L P -- L Q I P DDV ------- R DK AAL L HFYQNWQPQWT PG A K RL Y ANSSIG L F G ALAVKPS G MSYEEAMTRRVLQ PL 202
Cdd:PRK03642 157 - HSA G F P ad P Q Y P NKA vagalys Q DK STT L EMIKKTPLEYQ PG S K HI Y SDVDYM L L G FIVESIT G QPLDRYVEESIYR PL 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 203 K L A HT WITVP Q N -- EQKDY A RGYRE G KP ------------------ VH ----- V S P G QLDAE A y G VK S SVI DMA RWV Q AN 257
Cdd:PRK03642 236 G L T HT VFNPL Q K gf KPQQI A ATELN G NT rdgvihfpnirtntlwgq VH dekaf Y S M G GVSGH A - G LF S NTG DMA VLM Q VM 314
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2959382 258 MDASHVQEKT L QQGIALAQSRYWRIG D MYQ GLGW E mlnwplkadsi I NG SD S K valaalpavevn P P APAVK AS W v HKT G 337
Cdd:PRK03642 315 LNGGGYGNVQ L FDAETVKMFTTSSKE D ATF GLGW R ----------- V NG NA S M ------------ T P TFGTL AS P - QTY G 370
410 420 430
....*....|....*....|....*....|.
gi 2959382 338 S TG GF G SYVAFV P EKNLG IVML A NK SY p N PV 368
Cdd:PRK03642 371 H TG WT G TVTVID P VNHMA IVML S NK PH - S PV 400
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
