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Conserved domains on  [gi|29566077|ref|NP_817647|]
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DNA primase [Mycobacterium phage Bxz2]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-CHC2 super family cl21601
CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.
 33-83 1.07e-15

CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.


The actual alignment was detected with superfamily member smart00400:

Pssm-ID: 451328 [Multi-domain]  Cd Length: 55  Bit Score: 66.16  E-value: 1.07e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 29566077     33 CPFHGDETPSASISFKHNAFRCFACPVKGSAVAIIKEQEEVSYAEAKRIAE 83
Cdd:smart00400   5 CPFHGEKTPSFSVSPDKQFFHCFGCGAGGNVISFLMKYDKLSFVEAVKKLA 55
 
Name Accession Description Interval E-value
ZnF_CHCC smart00400
zinc finger;
33-83 1.07e-15

zinc finger;


Pssm-ID: 128681 [Multi-domain]  Cd Length: 55  Bit Score: 66.16  E-value: 1.07e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 29566077     33 CPFHGDETPSASISFKHNAFRCFACPVKGSAVAIIKEQEEVSYAEAKRIAE 83
Cdd:smart00400   5 CPFHGEKTPSFSVSPDKQFFHCFGCGAGGNVISFLMKYDKLSFVEAVKKLA 55
zf-CHC2 pfam01807
CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.
 22-85 1.88e-13

CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.


Pssm-ID: 426447 [Multi-domain]  Cd Length: 95  Bit Score: 61.50  E-value: 1.88e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 29566077    22 RQGRNdwMKTRCPFHGDETPSASISFKHNAFRCFACPVKGSAVAIIKEQEEVSYAEAkriAEEL 85
Cdd:pfam01807  26 KRGKD--YVGLCPFHHEKTPSFTVSPDKQFYHCFGCGAGGDVIKFLMKIEKLSFVEA---VEKL 84
dnaG TIGR01391
DNA primase, catalytic core; Members of this family are DNA primase, a ubiquitous bacteria ...
 22-85 7.08e-13

DNA primase, catalytic core; Members of this family are DNA primase, a ubiquitous bacteria protein. Most members of this family contain nearly two hundred additional residues C-terminal to the region represented here, but conservation between species is poor and the C-terminal region was not included in the seed alignment. This protein contains a CHC2 zinc finger (pfam01807) and a Toprim domain (pfam01751). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273595 [Multi-domain]  Cd Length: 415  Bit Score: 63.78  E-value: 7.08e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 29566077    22 RQGRNDWmkTRCPFHGDETPSASISFKHNAFRCFACPVKGSAVAIIKEQEEVSYAEA-KRIAEEL 85
Cdd:TIGR01391  28 KKGRNYV--GLCPFHHEKTPSFSVSPEKQFYHCFGCGAGGDAIKFLMEIEGISFVEAvEELAKRA 90
DnaG COG0358
DNA primase (bacterial type) [Replication, recombination and repair];
7-106 4.30e-12

DNA primase (bacterial type) [Replication, recombination and repair];


Pssm-ID: 440127 [Multi-domain]  Cd Length: 465  Bit Score: 61.69  E-value: 4.30e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29566077   7 IVKVIHRYHPeWEppRQGRNdwMKTRCPFHGDETPSASISFKHNAFRCFACPVKGSAVAIIKEQEEVSYAEA-KRIAEEL 85
Cdd:COG0358  16 IVDVIGEYVK-LK--KAGRN--YKGLCPFHDEKTPSFTVSPEKQFYHCFGCGAGGDVISFLMEYEGLSFPEAvEELAERA 90

                        90       100
                ....*....|....*....|....
gi 29566077  86 S---PGGDGTIPAQPSRQSRRRVF 106
Cdd:COG0358  91 GielPEEEGSPEEREEASERERLY 114
 
Name Accession Description Interval E-value
ZnF_CHCC smart00400
zinc finger;
33-83 1.07e-15

zinc finger;


Pssm-ID: 128681 [Multi-domain]  Cd Length: 55  Bit Score: 66.16  E-value: 1.07e-15
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|.
gi 29566077     33 CPFHGDETPSASISFKHNAFRCFACPVKGSAVAIIKEQEEVSYAEAKRIAE 83
Cdd:smart00400   5 CPFHGEKTPSFSVSPDKQFFHCFGCGAGGNVISFLMKYDKLSFVEAVKKLA 55
zf-CHC2 pfam01807
CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.
 22-85 1.88e-13

CHC2 zinc finger; This domain is principally involved in DNA binding in DNA primases.


Pssm-ID: 426447 [Multi-domain]  Cd Length: 95  Bit Score: 61.50  E-value: 1.88e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 29566077    22 RQGRNdwMKTRCPFHGDETPSASISFKHNAFRCFACPVKGSAVAIIKEQEEVSYAEAkriAEEL 85
Cdd:pfam01807  26 KRGKD--YVGLCPFHHEKTPSFTVSPDKQFYHCFGCGAGGDVIKFLMKIEKLSFVEA---VEKL 84
dnaG TIGR01391
DNA primase, catalytic core; Members of this family are DNA primase, a ubiquitous bacteria ...
 22-85 7.08e-13

DNA primase, catalytic core; Members of this family are DNA primase, a ubiquitous bacteria protein. Most members of this family contain nearly two hundred additional residues C-terminal to the region represented here, but conservation between species is poor and the C-terminal region was not included in the seed alignment. This protein contains a CHC2 zinc finger (pfam01807) and a Toprim domain (pfam01751). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273595 [Multi-domain]  Cd Length: 415  Bit Score: 63.78  E-value: 7.08e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 29566077    22 RQGRNDWmkTRCPFHGDETPSASISFKHNAFRCFACPVKGSAVAIIKEQEEVSYAEA-KRIAEEL 85
Cdd:TIGR01391  28 KKGRNYV--GLCPFHHEKTPSFSVSPEKQFYHCFGCGAGGDAIKFLMEIEGISFVEAvEELAKRA 90
DnaG COG0358
DNA primase (bacterial type) [Replication, recombination and repair];
7-106 4.30e-12

DNA primase (bacterial type) [Replication, recombination and repair];


Pssm-ID: 440127 [Multi-domain]  Cd Length: 465  Bit Score: 61.69  E-value: 4.30e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 29566077   7 IVKVIHRYHPeWEppRQGRNdwMKTRCPFHGDETPSASISFKHNAFRCFACPVKGSAVAIIKEQEEVSYAEA-KRIAEEL 85
Cdd:COG0358  16 IVDVIGEYVK-LK--KAGRN--YKGLCPFHDEKTPSFTVSPEKQFYHCFGCGAGGDVISFLMEYEGLSFPEAvEELAERA 90

                        90       100
                ....*....|....*....|....
gi 29566077  86 S---PGGDGTIPAQPSRQSRRRVF 106
Cdd:COG0358  91 GielPEEEGSPEEREEASERERLY 114
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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