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Conserved domains on  [gi|295432407|gb|ADG11579|]
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TonB-dependent receptor [Caulobacter segnis ATCC 21756]

Protein Classification

TonB-dependent receptor( domain architecture ID 1003665)

TonB-dependent receptor may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0015891

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TonB-Xanth-Caul super family cl36973
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 45-892 0e+00

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


The actual alignment was detected with superfamily member TIGR01782:

Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 589.69  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407   45 VDEVIVTAFRKSLATALEVKRKDVRVSDGISSEDIGKFPSENIAEAIQRIPGVQISNINGRGSTISIRGLGPQYALTTVN 124
Cdd:TIGR01782   1 LDAVQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  125 GQAFKSSNF-TDGFRYDVIQTELASGIQVYKSPTAEMDAGGLAGTVNIDTVHPFDVKGRQIILAGKLQKQDLVGGD-PTG 202
Cdd:TIGR01782  81 GRTIASTDSgGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGGYNDLAGKDkPGP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  203 KYGLTYVDHFLDGKLGVFLGGGYQELKDRGDYLWMDRWT-------VSNNVYTPARLRYRRIDRETKRSMLNGALQFKPT 275
Cdd:TIGR01782 161 RGAASYSWTFGDGQFGVLLSASYQKRDFAEDNVETENWGtytsadgGAQGLYFPRGVRYRSYRNDRERKGVNGSLQWRPS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  276 SDLQIDLIGTYAEDKTTQH-IHQQVFLFTTPSASNVVPVTVTNGTATKVQVNNFRLENNHQYENRPQSTGALTANVHYTG 354
Cdd:TIGR01782 241 DALELYLDTLYSKYDDDETrQQIEFRTLNGGSTVITSNQTATSGALVQGTVANLQILVEARYNEEKETTTSLTLGGEWTG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  355 iENWDFKATGHYSRGSAKHNEEAAILGVNiPSATVDI--SNPKNIVFTTSTALTDTAQYNPSSLIRNTYPNGAFRTIDSY 432
Cdd:TIGR01782 321 -DRWTLDGDLGYSKATRDRPDRVTRFFTA-PTPGYDFdyRGGPTLTLGTPADGDDASNYTNPANGELRRTQISYQKAEDS 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  433 EDAAQFDAKRFldwGVLESVQAGAK-IRHEVLKRYVIRRDGQNTIPASYSPTMASSGLSITNFMDGEATLPAAWVSPNLD 511
Cdd:TIGR01782 399 EDAAQLDATFD---GPFTSLKFGVRyRRRDKTNRGSRYRRSIIGATGASGLAGVPSDLAGAGLDGGLGGPLTGWDPADLD 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  512 AYREALKAQ----GVTVYEAFDPaGSYRVERDLTSFYAMANLKGEVlskTFRGNVGVRSESTDQTIDGYiggAANPLNTE 587
Cdd:TIGR01782 476 AFLNAARGDaaggGTYTYASTAP-NTYTVTEDTTAAYAMANFDTGL---RLRGNVGVRYERTDQTSDGW---QSQPAANG 548

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  588 VKLVAGTYTAKKSYDNILPSANFSLDLTDNLLLRVAAAKVLVRPIIDssnQLARTMTSTTDTSGvKVFTISTGQGNLDPM 667
Cdd:TIGR01782 549 TGSVLVPVSADRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFG---DLAANTSLSDDGTG-GTVTVSGGNPDLKPY 624

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  668 TANQLDLTLEWYYGQGNGLSAGYFSKKVKNGVYSQLSCPTAyegvslskntsGVCVAGNGDNYMITESLNDSKVVDIHGY 747
Cdd:TIGR01782 625 ESDNLDLSLEWYFGPGGLLSAAVFYKDIKNFIVTTTSTETN-----------DGGGGLVVAGVLVSRPVNGGKAGKIRGV 693

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  748 EVNWQQSLDAWL-PINGFGLIANYTHVNP--AQSTTG-----FRLANLSEHTANGTLYWENQTFSARLSANYRSAYDQTs 819
Cdd:TIGR01782 694 ELGYQQTFDFLPgPLSGFGVQANYTYVDSeaDPSVDGvqrrkLPLPGLSKNTANATLYYEKGGFSARLSYNYRSDYLLD- 772

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 295432407  820 VESFFAGPLGHTVKSRTQLDLNLGYNFNEHLSFAFAAMNINNAQEEAYLGNSSRWQETSVTGPSYYLSFQYKM 892
Cdd:TIGR01782 773 VGGSNINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYKF 845
 
Name Accession Description Interval E-value
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 45-892 0e+00

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 589.69  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407   45 VDEVIVTAFRKSLATALEVKRKDVRVSDGISSEDIGKFPSENIAEAIQRIPGVQISNINGRGSTISIRGLGPQYALTTVN 124
Cdd:TIGR01782   1 LDAVQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  125 GQAFKSSNF-TDGFRYDVIQTELASGIQVYKSPTAEMDAGGLAGTVNIDTVHPFDVKGRQIILAGKLQKQDLVGGD-PTG 202
Cdd:TIGR01782  81 GRTIASTDSgGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGGYNDLAGKDkPGP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  203 KYGLTYVDHFLDGKLGVFLGGGYQELKDRGDYLWMDRWT-------VSNNVYTPARLRYRRIDRETKRSMLNGALQFKPT 275
Cdd:TIGR01782 161 RGAASYSWTFGDGQFGVLLSASYQKRDFAEDNVETENWGtytsadgGAQGLYFPRGVRYRSYRNDRERKGVNGSLQWRPS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  276 SDLQIDLIGTYAEDKTTQH-IHQQVFLFTTPSASNVVPVTVTNGTATKVQVNNFRLENNHQYENRPQSTGALTANVHYTG 354
Cdd:TIGR01782 241 DALELYLDTLYSKYDDDETrQQIEFRTLNGGSTVITSNQTATSGALVQGTVANLQILVEARYNEEKETTTSLTLGGEWTG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  355 iENWDFKATGHYSRGSAKHNEEAAILGVNiPSATVDI--SNPKNIVFTTSTALTDTAQYNPSSLIRNTYPNGAFRTIDSY 432
Cdd:TIGR01782 321 -DRWTLDGDLGYSKATRDRPDRVTRFFTA-PTPGYDFdyRGGPTLTLGTPADGDDASNYTNPANGELRRTQISYQKAEDS 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  433 EDAAQFDAKRFldwGVLESVQAGAK-IRHEVLKRYVIRRDGQNTIPASYSPTMASSGLSITNFMDGEATLPAAWVSPNLD 511
Cdd:TIGR01782 399 EDAAQLDATFD---GPFTSLKFGVRyRRRDKTNRGSRYRRSIIGATGASGLAGVPSDLAGAGLDGGLGGPLTGWDPADLD 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  512 AYREALKAQ----GVTVYEAFDPaGSYRVERDLTSFYAMANLKGEVlskTFRGNVGVRSESTDQTIDGYiggAANPLNTE 587
Cdd:TIGR01782 476 AFLNAARGDaaggGTYTYASTAP-NTYTVTEDTTAAYAMANFDTGL---RLRGNVGVRYERTDQTSDGW---QSQPAANG 548

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  588 VKLVAGTYTAKKSYDNILPSANFSLDLTDNLLLRVAAAKVLVRPIIDssnQLARTMTSTTDTSGvKVFTISTGQGNLDPM 667
Cdd:TIGR01782 549 TGSVLVPVSADRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFG---DLAANTSLSDDGTG-GTVTVSGGNPDLKPY 624

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  668 TANQLDLTLEWYYGQGNGLSAGYFSKKVKNGVYSQLSCPTAyegvslskntsGVCVAGNGDNYMITESLNDSKVVDIHGY 747
Cdd:TIGR01782 625 ESDNLDLSLEWYFGPGGLLSAAVFYKDIKNFIVTTTSTETN-----------DGGGGLVVAGVLVSRPVNGGKAGKIRGV 693

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  748 EVNWQQSLDAWL-PINGFGLIANYTHVNP--AQSTTG-----FRLANLSEHTANGTLYWENQTFSARLSANYRSAYDQTs 819
Cdd:TIGR01782 694 ELGYQQTFDFLPgPLSGFGVQANYTYVDSeaDPSVDGvqrrkLPLPGLSKNTANATLYYEKGGFSARLSYNYRSDYLLD- 772

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 295432407  820 VESFFAGPLGHTVKSRTQLDLNLGYNFNEHLSFAFAAMNINNAQEEAYLGNSSRWQETSVTGPSYYLSFQYKM 892
Cdd:TIGR01782 773 VGGSNINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYKF 845
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 70-891 3.59e-76

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 261.23  E-value: 3.59e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  70 VSDGISSEDIGKFPSENIAEAIQRIPGVQISNIN-GRGSTISIRGLGPQYALTTVNGQAFKSSNFTDGFRYDVIQTELAS 148
Cdd:cd01347    1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGgGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNTIPPELIE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 149 GIQVYKSPTAEM-DAGGLAGTVNIDTVHPFDVKGRQIilagklqkqdlvggdpTGKYGLTYVDHFLDGKLGVFLGGGYQE 227
Cdd:cd01347   81 RVEVLKGPSSALyGSGAIGGVVNIITKRPTDEFGGSV----------------TAGYGSDNSGSSGGGGFDVSGALADDG 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 228 lkdrgdylWMDRWTVSNNVYTPARLRY--RRIDRETKRSMLNGALQFKPTSDLQIDLIGTYAEDKTTQHIHQQVFLFTTP 305
Cdd:cd01347  145 --------AFGARLYGAYRDGDGTIDGdgQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGS 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 306 SAsnvvpvtvtNGTATKVQVNNFRLENNHQYENRPQSTGALTANvhytgIENWDFKATGHYSRgsAKHNEEAAILGVNIP 385
Cdd:cd01347  217 SL---------GGGPSSNTNGDRDWDYRDRYRKRASLGLEHDLN-----DTGWTLRANLSYSY--TDNDGDPLILNGGNN 280

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 386 SATVDISNPKNIVFTTSTALTDTAQYNpsslirntypngafrtidsyedaaqfdaKRFLDWGVLESVQAGakirhevlkr 465
Cdd:cd01347  281 AAGGDLGRSGYSSERDTTQLGFDAGLN----------------------------APFGTGPVAHTLTLG---------- 322

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 466 yvirrdgqntipasysptmassglsitnfmdgeatlpaawvspnLDAYREalkaqgvtvyeafdpagsyRVERDLTSFYA 545
Cdd:cd01347  323 --------------------------------------------VEYRRE-------------------ELDEKQTALYA 339

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 546 MANLKgevLSKTFRGNVGVRSESTDQTIDGYIggaanplntevklvAGTYTAKKSYDNILPSANFSLDLTDNLLLRVAAA 625
Cdd:cd01347  340 QDTIE---LTDDLTLTLGLRYDHYDQDSKDTI--------------AGGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYS 402

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 626 KVLVRPIIDSSNQlartmtsttdtSGVKVFTISTGQGNLDPMTANQLDLTLEWYYGQGNGLSAGYFSKKVKNGVYSQlsc 705
Cdd:cd01347  403 QGFRAPSLGELYG-----------GGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVST--- 468

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 706 ptayegvslskntsgvcvAGNGDNYMITESLNDSKVVdIHGYEVNWQQSLDAwlpinGFGLIANYTHVN-----PAQSTT 780
Cdd:cd01347  469 ------------------PTNTGLGLVTVYVNGGKAR-IRGVELEASYDLTD-----GLGLTGSYTYTDtevkrTDGATT 524

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 781 GFRLANLSEHTANGTLYWE--NQTFSARLSANYRSAYDQTSVesffAGPLGHTVKSRTQLDLNLGYNFNEHLSFAFAAMN 858
Cdd:cd01347  525 GNRLPGIPKHTANLGLDYElpDEGLTAGGGVRYRGKQYADTA----NGNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNN 600

                        810       820       830
                 ....*....|....*....|....*....|....
gi 295432407 859 INNAQEEAYLGN-SSRWQETSVTGPSYYLSFQYK 891
Cdd:cd01347  601 LFDKDYYTSLSVrGSGLYGYYGPGRTYYLSVSYK 634
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
45-861 4.27e-29

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 123.78  E-value: 4.27e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  45 VDEVIVTAfrkslaTALEVKRKDVRVSDG-ISSEDIGKFPSENIAEAIQRIPGVQISNINGRGSTISIRGLG--PQYALT 121
Cdd:COG1629    1 LEEVVVTA------TRTDESLQDVPGSVSvISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGggGNRVLV 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 122 TVNGQAFkSSNFTDGFRYDVIQTELASGIQVYKSPTAEM-DAGGLAGTVNIDTVHPFDVKGRQIilagKLQkqdlVGGDP 200
Cdd:COG1629   75 LVDGVPL-NDPSGGDGGLSYIDPEDIERVEVLRGPSSALyGSGALGGVINIVTKKPKDGKGGEV----SAS----YGSYG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 201 TGKYGLTYVDHflDGKLGVFLGGGYQelkDRGDYlwmdrwtvsnnvytparlryrRIDRETKRSMLNGALQFKPTSDLQI 280
Cdd:COG1629  146 TYRASLSLSGG--NGKLAYRLSASYR---DSDGY---------------------RDNSDSDRYNLRAKLGYQLGDDTRL 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 281 DLIGTYAEDKTTQHihqqvflfTTPSASNVVPVTVTNGTATKVQVNNFRLENNHqyenrpqstgaLTANVHYTGI-ENWD 359
Cdd:COG1629  200 TLSASYSDSDQDSP--------GYLTLAALRPRGAMDDGTNPYSNDTDDNTRDR-----------YSLSLEYEHLgDGLK 260

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 360 FKATGHYSRgsakhneeaailgvnipsatvdisnpknivFTTSTALTDTAQYNPSSLIRNTYPNGAFRTIDsyedaAQFD 439
Cdd:COG1629  261 LSASAYYRY------------------------------DDTDLDSDFTPTPADGGTLEQTDFDNRTYGLE-----LRLT 305

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 440 AKRFLDWGVleSVQAGAKIRHEVLKRYVIRRDGQNTIPASYSPTmassglsitnfmdgeatlpaawvspnldayrealka 519
Cdd:COG1629  306 YDLGFGGKH--TLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSG------------------------------------ 347

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 520 qgvtvyeafdpaGSYRVERDLTSFYAMANLKgevLSKTFRGNVGVRSESTDQTIDGYIGGAANplntevklvagtYTAKK 599
Cdd:COG1629  348 ------------ADDDGTTTSLALYAQDTYK---LTDKLTLTAGLRYDYVSYDVDDTVTGTDS------------ASGSR 400

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 600 SYDNILPSANFSLDLTDNLLLRVAAAKVLVRPiidssnqlartmtSTTDTSGVKVFTISTGQGNLDPMTANQLDLTLEWY 679
Cdd:COG1629  401 SYSAFSPSLGLTYQLSPNLSLYASYSRGFRAP-------------TFGELYANGTDPYSVGNPDLKPETSTNYELGLRYR 467

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 680 YGQGN-GLSAGYFSKKVKNGVYSQlscptayegvslskntsgvcvAGNGDNYMITESLNDSKvVDIHGYEVNWqqsldAW 758
Cdd:COG1629  468 LLDGRlSLSLALFYSDVDNEILSV---------------------PLPNDSGFSTYYTNAGK-ARSYGVELEL-----SY 520

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 759 LPINGFGLIANYTHV--------NPAQSTTGFRLANLSEHTANGTLYWE-NQTFSARLSANYRSAYDQTSVESFFAGPlg 829
Cdd:COG1629  521 QLTPGLSLNASYSYTdakfdddtDGSADLDGNRLPGVPPLTANLGLTYEfPGGWSLGLGVRYVGDRYLDDANTQGAPG-- 598

                        810       820       830
                 ....*....|....*....|....*....|..
gi 295432407 830 htvkSRTQLDLNLGYNFNEHLSFAFAAMNINN 861
Cdd:COG1629  599 ----GYTLVDLGAGYRFGDNLTLSLGVDNLFD 626
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 399-891 5.95e-23

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 103.31  E-value: 5.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  399 FTTSTALTDTAQYNPSSLIRNTYPNGAFRTIDSYEDAAQFDAKRFLDWGVLESVQAGA---KIRHEVLKRYVIRRDGQNT 475
Cdd:pfam00593  28 LDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLrysSLDGDYTSNSSGLSGAGDY 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  476 IPASYSPTMASSGLSITNFMDGEATLPAAWVSPNLDAYREALKAQGVTVYEAFDPAGSY--RVERDLTSFYAMANLKgev 553
Cdd:pfam00593 108 LSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSysDTTTDSYGLYLQDNIK--- 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  554 LSKTFRGNVGVRSESTDQTIDGYIGGAANplntevklvagtytAKKSYDNILPSANFSLDLTDNLLLRVAAAKVLVRPii 633
Cdd:pfam00593 185 LTDRLTLTLGLRYDHYSTDGDDGNGGGDN--------------FSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAP-- 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  634 dSSNQLartmtsTTDTSGVKVFTISTGQGNLDPMTANQLDLTLEWYYGQGNgLSAGYFSKKVKNGVYSQLSCPTAYEGVS 713
Cdd:pfam00593 249 -SLGEL------YGSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLS-LSLALFYIDIKNLITSDPDGPGLGGTVY 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  714 LSKNTSGVcvagngdnymiteslndskvvDIHGYEVNWqqSLDAWLPINGFGLIANY-THVNPAQSTTGFRLANLSEHTA 792
Cdd:pfam00593 321 TYTNVGKA---------------------RIRGVELEL--SGRLWGLGLSGGGYTYTdADDDADADDTGNPLPNVPRHTA 377

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  793 NGTLYWENQT--FSARLSANYRSAYDQTSVESffagPLGHTVKSRTQLDLNLGYNFNEHLSFAFAAMNINNAQEEAYLGN 870
Cdd:pfam00593 378 NLGLTYDFPLggWGARLGARYVGSGERRYGDA----ANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSS 453

                         490       500
                  ....*....|....*....|..
gi 295432407  871 SSRWQETSVTGP-SYYLSFQYK 891
Cdd:pfam00593 454 GGGNLGGYPGPGrTFYLGLSYK 475
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 46-173 2.10e-08

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 57.97  E-value: 2.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  46 DEVIVTAfrkslaTALEVKRKDVRVS-DGISSEDIGKFPSENIAEAIQRIPGVQISNINGRGSTISIRGLGPQYALTTVN 124
Cdd:PRK10064  31 ETMVVTA------SAVEQNLKDAPASiSVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLILID 104

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 295432407 125 GQAFKSSNFT---DGFRYDVIQTELASGIQVYKSPTAEM---DAggLAGTVNIDT 173
Cdd:PRK10064 105 GKRVNSRNAVfrhNDFDLNWIPVDAIERIEVVRGPMSSLygsDA--LGGVVNIIT 157
 
Name Accession Description Interval E-value
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 45-892 0e+00

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 589.69  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407   45 VDEVIVTAFRKSLATALEVKRKDVRVSDGISSEDIGKFPSENIAEAIQRIPGVQISNINGRGSTISIRGLGPQYALTTVN 124
Cdd:TIGR01782   1 LDAVQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  125 GQAFKSSNF-TDGFRYDVIQTELASGIQVYKSPTAEMDAGGLAGTVNIDTVHPFDVKGRQIILAGKLQKQDLVGGD-PTG 202
Cdd:TIGR01782  81 GRTIASTDSgGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGGYNDLAGKDkPGP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  203 KYGLTYVDHFLDGKLGVFLGGGYQELKDRGDYLWMDRWT-------VSNNVYTPARLRYRRIDRETKRSMLNGALQFKPT 275
Cdd:TIGR01782 161 RGAASYSWTFGDGQFGVLLSASYQKRDFAEDNVETENWGtytsadgGAQGLYFPRGVRYRSYRNDRERKGVNGSLQWRPS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  276 SDLQIDLIGTYAEDKTTQH-IHQQVFLFTTPSASNVVPVTVTNGTATKVQVNNFRLENNHQYENRPQSTGALTANVHYTG 354
Cdd:TIGR01782 241 DALELYLDTLYSKYDDDETrQQIEFRTLNGGSTVITSNQTATSGALVQGTVANLQILVEARYNEEKETTTSLTLGGEWTG 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  355 iENWDFKATGHYSRGSAKHNEEAAILGVNiPSATVDI--SNPKNIVFTTSTALTDTAQYNPSSLIRNTYPNGAFRTIDSY 432
Cdd:TIGR01782 321 -DRWTLDGDLGYSKATRDRPDRVTRFFTA-PTPGYDFdyRGGPTLTLGTPADGDDASNYTNPANGELRRTQISYQKAEDS 398

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  433 EDAAQFDAKRFldwGVLESVQAGAK-IRHEVLKRYVIRRDGQNTIPASYSPTMASSGLSITNFMDGEATLPAAWVSPNLD 511
Cdd:TIGR01782 399 EDAAQLDATFD---GPFTSLKFGVRyRRRDKTNRGSRYRRSIIGATGASGLAGVPSDLAGAGLDGGLGGPLTGWDPADLD 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  512 AYREALKAQ----GVTVYEAFDPaGSYRVERDLTSFYAMANLKGEVlskTFRGNVGVRSESTDQTIDGYiggAANPLNTE 587
Cdd:TIGR01782 476 AFLNAARGDaaggGTYTYASTAP-NTYTVTEDTTAAYAMANFDTGL---RLRGNVGVRYERTDQTSDGW---QSQPAANG 548

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  588 VKLVAGTYTAKKSYDNILPSANFSLDLTDNLLLRVAAAKVLVRPIIDssnQLARTMTSTTDTSGvKVFTISTGQGNLDPM 667
Cdd:TIGR01782 549 TGSVLVPVSADRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFG---DLAANTSLSDDGTG-GTVTVSGGNPDLKPY 624

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  668 TANQLDLTLEWYYGQGNGLSAGYFSKKVKNGVYSQLSCPTAyegvslskntsGVCVAGNGDNYMITESLNDSKVVDIHGY 747
Cdd:TIGR01782 625 ESDNLDLSLEWYFGPGGLLSAAVFYKDIKNFIVTTTSTETN-----------DGGGGLVVAGVLVSRPVNGGKAGKIRGV 693

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  748 EVNWQQSLDAWL-PINGFGLIANYTHVNP--AQSTTG-----FRLANLSEHTANGTLYWENQTFSARLSANYRSAYDQTs 819
Cdd:TIGR01782 694 ELGYQQTFDFLPgPLSGFGVQANYTYVDSeaDPSVDGvqrrkLPLPGLSKNTANATLYYEKGGFSARLSYNYRSDYLLD- 772

                         810       820       830       840       850       860       870
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 295432407  820 VESFFAGPLGHTVKSRTQLDLNLGYNFNEHLSFAFAAMNINNAQEEAYLGNSSRWQETSVTGPSYYLSFQYKM 892
Cdd:TIGR01782 773 VGGSNINRLDRYVDPRGQLDLSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYKF 845
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 70-891 3.59e-76

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 261.23  E-value: 3.59e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  70 VSDGISSEDIGKFPSENIAEAIQRIPGVQISNIN-GRGSTISIRGLGPQYALTTVNGQAFKSSNFTDGFRYDVIQTELAS 148
Cdd:cd01347    1 SVSVITAEDIEKQPATSLADLLRRIPGVSVTRGGgGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNTIPPELIE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 149 GIQVYKSPTAEM-DAGGLAGTVNIDTVHPFDVKGRQIilagklqkqdlvggdpTGKYGLTYVDHFLDGKLGVFLGGGYQE 227
Cdd:cd01347   81 RVEVLKGPSSALyGSGAIGGVVNIITKRPTDEFGGSV----------------TAGYGSDNSGSSGGGGFDVSGALADDG 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 228 lkdrgdylWMDRWTVSNNVYTPARLRY--RRIDRETKRSMLNGALQFKPTSDLQIDLIGTYAEDKTTQHIHQQVFLFTTP 305
Cdd:cd01347  145 --------AFGARLYGAYRDGDGTIDGdgQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGS 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 306 SAsnvvpvtvtNGTATKVQVNNFRLENNHQYENRPQSTGALTANvhytgIENWDFKATGHYSRgsAKHNEEAAILGVNIP 385
Cdd:cd01347  217 SL---------GGGPSSNTNGDRDWDYRDRYRKRASLGLEHDLN-----DTGWTLRANLSYSY--TDNDGDPLILNGGNN 280

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 386 SATVDISNPKNIVFTTSTALTDTAQYNpsslirntypngafrtidsyedaaqfdaKRFLDWGVLESVQAGakirhevlkr 465
Cdd:cd01347  281 AAGGDLGRSGYSSERDTTQLGFDAGLN----------------------------APFGTGPVAHTLTLG---------- 322

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 466 yvirrdgqntipasysptmassglsitnfmdgeatlpaawvspnLDAYREalkaqgvtvyeafdpagsyRVERDLTSFYA 545
Cdd:cd01347  323 --------------------------------------------VEYRRE-------------------ELDEKQTALYA 339

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 546 MANLKgevLSKTFRGNVGVRSESTDQTIDGYIggaanplntevklvAGTYTAKKSYDNILPSANFSLDLTDNLLLRVAAA 625
Cdd:cd01347  340 QDTIE---LTDDLTLTLGLRYDHYDQDSKDTI--------------AGGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYS 402

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 626 KVLVRPIIDSSNQlartmtsttdtSGVKVFTISTGQGNLDPMTANQLDLTLEWYYGQGNGLSAGYFSKKVKNGVYSQlsc 705
Cdd:cd01347  403 QGFRAPSLGELYG-----------GGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGDGLTLSAALFRIDIKNEIVST--- 468

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 706 ptayegvslskntsgvcvAGNGDNYMITESLNDSKVVdIHGYEVNWQQSLDAwlpinGFGLIANYTHVN-----PAQSTT 780
Cdd:cd01347  469 ------------------PTNTGLGLVTVYVNGGKAR-IRGVELEASYDLTD-----GLGLTGSYTYTDtevkrTDGATT 524

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 781 GFRLANLSEHTANGTLYWE--NQTFSARLSANYRSAYDQTSVesffAGPLGHTVKSRTQLDLNLGYNFNEHLSFAFAAMN 858
Cdd:cd01347  525 GNRLPGIPKHTANLGLDYElpDEGLTAGGGVRYRGKQYADTA----NGNNTVKVPGYTLVDLSASYQFTKNLTLRLGVNN 600

                        810       820       830
                 ....*....|....*....|....*....|....
gi 295432407 859 INNAQEEAYLGN-SSRWQETSVTGPSYYLSFQYK 891
Cdd:cd01347  601 LFDKDYYTSLSVrGSGLYGYYGPGRTYYLSVSYK 634
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
45-861 4.27e-29

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 123.78  E-value: 4.27e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  45 VDEVIVTAfrkslaTALEVKRKDVRVSDG-ISSEDIGKFPSENIAEAIQRIPGVQISNINGRGSTISIRGLG--PQYALT 121
Cdd:COG1629    1 LEEVVVTA------TRTDESLQDVPGSVSvISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGggGNRVLV 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 122 TVNGQAFkSSNFTDGFRYDVIQTELASGIQVYKSPTAEM-DAGGLAGTVNIDTVHPFDVKGRQIilagKLQkqdlVGGDP 200
Cdd:COG1629   75 LVDGVPL-NDPSGGDGGLSYIDPEDIERVEVLRGPSSALyGSGALGGVINIVTKKPKDGKGGEV----SAS----YGSYG 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 201 TGKYGLTYVDHflDGKLGVFLGGGYQelkDRGDYlwmdrwtvsnnvytparlryrRIDRETKRSMLNGALQFKPTSDLQI 280
Cdd:COG1629  146 TYRASLSLSGG--NGKLAYRLSASYR---DSDGY---------------------RDNSDSDRYNLRAKLGYQLGDDTRL 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 281 DLIGTYAEDKTTQHihqqvflfTTPSASNVVPVTVTNGTATKVQVNNFRLENNHqyenrpqstgaLTANVHYTGI-ENWD 359
Cdd:COG1629  200 TLSASYSDSDQDSP--------GYLTLAALRPRGAMDDGTNPYSNDTDDNTRDR-----------YSLSLEYEHLgDGLK 260

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 360 FKATGHYSRgsakhneeaailgvnipsatvdisnpknivFTTSTALTDTAQYNPSSLIRNTYPNGAFRTIDsyedaAQFD 439
Cdd:COG1629  261 LSASAYYRY------------------------------DDTDLDSDFTPTPADGGTLEQTDFDNRTYGLE-----LRLT 305

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 440 AKRFLDWGVleSVQAGAKIRHEVLKRYVIRRDGQNTIPASYSPTmassglsitnfmdgeatlpaawvspnldayrealka 519
Cdd:COG1629  306 YDLGFGGKH--TLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSG------------------------------------ 347

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 520 qgvtvyeafdpaGSYRVERDLTSFYAMANLKgevLSKTFRGNVGVRSESTDQTIDGYIGGAANplntevklvagtYTAKK 599
Cdd:COG1629  348 ------------ADDDGTTTSLALYAQDTYK---LTDKLTLTAGLRYDYVSYDVDDTVTGTDS------------ASGSR 400

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 600 SYDNILPSANFSLDLTDNLLLRVAAAKVLVRPiidssnqlartmtSTTDTSGVKVFTISTGQGNLDPMTANQLDLTLEWY 679
Cdd:COG1629  401 SYSAFSPSLGLTYQLSPNLSLYASYSRGFRAP-------------TFGELYANGTDPYSVGNPDLKPETSTNYELGLRYR 467

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 680 YGQGN-GLSAGYFSKKVKNGVYSQlscptayegvslskntsgvcvAGNGDNYMITESLNDSKvVDIHGYEVNWqqsldAW 758
Cdd:COG1629  468 LLDGRlSLSLALFYSDVDNEILSV---------------------PLPNDSGFSTYYTNAGK-ARSYGVELEL-----SY 520

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 759 LPINGFGLIANYTHV--------NPAQSTTGFRLANLSEHTANGTLYWE-NQTFSARLSANYRSAYDQTSVESFFAGPlg 829
Cdd:COG1629  521 QLTPGLSLNASYSYTdakfdddtDGSADLDGNRLPGVPPLTANLGLTYEfPGGWSLGLGVRYVGDRYLDDANTQGAPG-- 598

                        810       820       830
                 ....*....|....*....|....*....|..
gi 295432407 830 htvkSRTQLDLNLGYNFNEHLSFAFAAMNINN 861
Cdd:COG1629  599 ----GYTLVDLGAGYRFGDNLTLSLGVDNLFD 626
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 46-853 3.92e-27

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 117.65  E-value: 3.92e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  46 DEVIVTAfrkslaTALEVKRKDVRVS-DGISSEDIGKFPSENIAEAIQRIPGVQISNINGRG--STISIRGLGPQYALTT 122
Cdd:COG4771   28 EEVVVTA------TRTEQSLSDAPASvSVITAEEIEKLGATDLADALRLLPGVSVTRSGGRGgsSGISIRGLGGDRVLVL 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 123 VNGQAFKSSNFTDGFRYDVIQTELASGIQVYKSP-TAEMDAGGLAGTVNIDTVHPFDVKGRQIILagklqkqdLVGGDPT 201
Cdd:COG4771  102 IDGVPVNNPALGGGGDLSYIPPDDIERIEVIRGPaSALYGSDAIGGVINIITKKPTDELEGSVSL--------GYGSNGN 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 202 GKYGLTYVDHFLDGKLGVFLGGGYQELKDRGDYlwmdrwtvsNNVYTPARLRYRRIDretkrsmLNGALQFKPTSDLQID 281
Cdd:COG4771  174 GTYSGSLSLGGPGDKLSFLLSGSYRDRDGYLDY---------RNGGFVGNSGYERYN-------LNAKLGYRLSDNHRLS 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 282 LIGTYAEDKTTqhihqqvflfttpsasnvvpvTVTNGTATKVQVNNFRLENNHQYENRpqstgalTANVHYTGIENWDFK 361
Cdd:COG4771  238 LSGGYSRQDRD---------------------GGPPTLGDTEISSDNAGDRDTTTDRG-------NYSLRYNGDLGDNLD 289

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 362 ATGHYSRgsakhneeaailgvnipsatvdisnpknivfttstalTDTAQYNPSSlirnTYPNGAFRTIDSYEDAAQFDAK 441
Cdd:COG4771  290 LSLYYSR-------------------------------------TDRDSTNGSL----GGSTGSFSDSDDTTYGLELDLT 328

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 442 RFLDWGVleSVQAGAKIRHEVLKRYVIRrdgqntipasysptmassglsitnfmdgeatlpaawvspnldayrealkaqg 521
Cdd:COG4771  329 YPLGGNH--TLTLGAEYRYDDLDSSSFL---------------------------------------------------- 354

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 522 vtvyeafdpaGSYRVERDLTSFYAMANLKgevLSKTFRGNVGVRSESTDqtidgyiggaanplntevklvagtYTAKKSY 601
Cdd:COG4771  355 ----------GGADASRDTYGLFAQDEWK---LTDKLTLTAGLRYDYYS------------------------TFGASNY 397

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 602 DNILPSANFSLDLTDNLLLRVAAAKVLVRPIIdssNQLARTMTSTTDtsgvkvfTISTGQGNLDPMTANQLDLTLEWYYG 681
Cdd:COG4771  398 TAFSPRLGLRYDLSDNLTLRASYGRGFRAPSL---AELYGSGTGTPG-------RYVLGNPDLKPETSDNYELGLEYRLG 467

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 682 QGNG-LSAGYFSKKVKNGVYSQLSCPtayegvslskntsgvcvaGNGDNYMITeslNDSKvVDIHGYEVNWQQSLDAWLp 760
Cdd:COG4771  468 NGGLsLSLTGFYTDIKDLIVLVPVGP------------------GPGDVLQYE---NVGK-ARTYGLELELKYRLGKGL- 524

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 761 inGFGLIANYTHVNPAQSTTGFRLANLSEHTANGTLYWenqTFSARLSANYRSAYDQTSVESFFAGPLGHTVKSRTQLDL 840
Cdd:COG4771  525 --TLTASYTYLDSKIDDGDTGEPLPNVPPHKANLGLDY---RLPKWWLLLLLTRYYGGRYVTPPSGRLEGYTPGYTLLDL 599

                        810
                 ....*....|...
gi 295432407 841 NLGYNFNEHLSFA 853
Cdd:COG4771  600 RASYKLTKNLTLS 612
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 399-891 5.95e-23

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 103.31  E-value: 5.95e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  399 FTTSTALTDTAQYNPSSLIRNTYPNGAFRTIDSYEDAAQFDAKRFLDWGVLESVQAGA---KIRHEVLKRYVIRRDGQNT 475
Cdd:pfam00593  28 LDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLrysSLDGDYTSNSSGLSGAGDY 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  476 IPASYSPTMASSGLSITNFMDGEATLPAAWVSPNLDAYREALKAQGVTVYEAFDPAGSY--RVERDLTSFYAMANLKgev 553
Cdd:pfam00593 108 LSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSSSysDTTTDSYGLYLQDNIK--- 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  554 LSKTFRGNVGVRSESTDQTIDGYIGGAANplntevklvagtytAKKSYDNILPSANFSLDLTDNLLLRVAAAKVLVRPii 633
Cdd:pfam00593 185 LTDRLTLTLGLRYDHYSTDGDDGNGGGDN--------------FSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAP-- 248

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  634 dSSNQLartmtsTTDTSGVKVFTISTGQGNLDPMTANQLDLTLEWYYGQGNgLSAGYFSKKVKNGVYSQLSCPTAYEGVS 713
Cdd:pfam00593 249 -SLGEL------YGSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLS-LSLALFYIDIKNLITSDPDGPGLGGTVY 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  714 LSKNTSGVcvagngdnymiteslndskvvDIHGYEVNWqqSLDAWLPINGFGLIANY-THVNPAQSTTGFRLANLSEHTA 792
Cdd:pfam00593 321 TYTNVGKA---------------------RIRGVELEL--SGRLWGLGLSGGGYTYTdADDDADADDTGNPLPNVPRHTA 377

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  793 NGTLYWENQT--FSARLSANYRSAYDQTSVESffagPLGHTVKSRTQLDLNLGYNFNEHLSFAFAAMNINNAQEEAYLGN 870
Cdd:pfam00593 378 NLGLTYDFPLggWGARLGARYVGSGERRYGDA----ANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSS 453

                         490       500
                  ....*....|....*....|..
gi 295432407  871 SSRWQETSVTGP-SYYLSFQYK 891
Cdd:pfam00593 454 GGGNLGGYPGPGrTFYLGLSYK 475
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 74-168 5.01e-16

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 74.61  E-value: 5.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407   74 ISSEDIGKFPSENIAEAIQRIPGVQISN-INGRGSTISIRGLGPQYALTTVNGQAFKSSNFTDGFRYDvIQTELASGIQV 152
Cdd:pfam07715  12 VTAEDIEDQGATNLADALRGVPGVSVSSgGGGGGSSISIRGFGSNRVLVLVDGVPLNSGGGGSVDLNS-IDPEDIERVEV 90

                          90
                  ....*....|....*..
gi 295432407  153 YKSP-TAEMDAGGLAGT 168
Cdd:pfam07715  91 LKGPaSALYGSGAIGGV 107
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
48-292 1.50e-14

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 74.91  E-value: 1.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  48 VIVTAFRkslataLEVKRKDVRVS-DGISSEDIGKFPSENIAEAIQRIPGVQISNINGRG--STISIRGLGPQYALTTVN 124
Cdd:COG4206    1 VVVTATR------LEQSKSDLTGSvTVIDAEELERSGATSLADALRRVPGVQVSSSGGPGsaASISIRGLGSNQTLVLID 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 125 GQAFkSSNFTDGFRYDVIQTELASGIQVYKSPTAEM-DAGGLAGTVNIDTVHPFDVKGRQIILAgklqkqdlVGGDPTGK 203
Cdd:COG4206   75 GVPL-NDPSLGGVDLSLIPPDDIERIEVLKGAASALyGSDAIGGVINITTKKGKKGFKGSVSAS--------YGSFGTRR 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 204 YGLTYvdHFLDGKLGVFLGGGYQelkDRGDYLWMDRWTVSNNVYtparlryrridretKRSMLNGALQFKPTSDLQIDLI 283
Cdd:COG4206  146 LSASL--SGGAGKFSYSLSASYR---RSDGYRYNDPDLRNNDGY--------------ENTSLNARLGYKLGDNGSLSLS 206


                 ....*....
gi 295432407 284 GTYAEDKTT 292
Cdd:COG4206  207 GGYSDSERG 215
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
45-872 4.78e-10

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 63.41  E-value: 4.78e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  45 VDEVIVTAFRKSLATALEVKRKDVRVSDgissEDIGKFPSENIAEAIQRIPGVQISNINGRG--STISIRGLGPQYA--- 119
Cdd:COG4772   23 LETVVVTGSRAAEARLKDVPGSVSVVDR----EELENQAATSLREVLRRVPGVNVQEEDGFGlrPNIGIRGLGPRRSrgi 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 120 LTTVNGQAFKSSNFTDGFRYDVIQTELASGIQVYKSPTAeMDAGGLA--GTVNIDTvhpfdvkgRQIILAGKLQKQDLVG 197
Cdd:COG4772   99 TLLEDGIPIAPAPYGDPAAYYFPDLERMERIEVLRGAAA-LRYGPQTvgGAINFVT--------RTIPTAFGGELRVTGG 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 198 GDPTGKYGLTYVDHFldGKLGVFLGGGYQelkdRGDYlWMDrwtvsnnvytparlryrriDRETKRSMLNGALQFKPTSD 277
Cdd:COG4772  170 SFGYRRTHASVGGTV--GNFGYLVEYSRK----RGDG-FRD-------------------NSGFDINDFNAKLGYRLSDR 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 278 LQIDLIGTYAEDKttqhihqqvflfttpsaSNvvpvtvTNGTATKVQVNNfrlennhqyeNRPQSTGALtanvhytgien 357
Cdd:COG4772  224 QELTLKFQYYDED-----------------AN------TPGGLTDAQFDA----------DPRQSYRPA----------- 259

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 358 wDFKATGHYsRGSAKHneeaailgvnipsatvdisnpkNIVFTTSTALTDTAQYNPSSliRNTYPNGAFRTIDSYEDAAQ 437
Cdd:COG4772  260 -DQFDTRRT-QLSLRY----------------------EHQLSDNTTLTTTAYYNDFS--RNWYIRQNTADPNTPGLGLR 313

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 438 FDAKRFLDWGvlesVQAGAKIRHEVLKRyvirrdgQNTIPASYsptmassglsitnfmdgeatlpaawvspnlDAYREAL 517
Cdd:COG4772  314 GNPRGYRSYG----IEPRLTHRFELGGV-------PHTLEVGL------------------------------RYHREEE 352

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 518 KA-QGVTVYE-AFDPAGSYRVERDLT---SFYAMANLKgevLSKTFRGNVGVRSESTDQTIDGYIGGAANplntevklva 592
Cdd:COG4772  353 DRkQYVNTYGqGRSGAGLRRDRRFSAdalAAYAQNRFE---LTGRLTLTPGLRYEHIRRDRTDRYSTRTG---------- 419

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 593 GTYTAKKSYDNILPSANFSLDLTDNLLLRVAAakvlvrpiidssnqlARTMTSTTDTSgvkVFTISTGQGNLDPMTANQL 672
Cdd:COG4772  420 GDDSGSNSYSEFLPGLGLLYQLTDNLQLYANV---------------SRGFEPPTFGD---LAYGNGGNPDLKPEKSWNY 481

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 673 DLTLEWYYGQGNGLSAGYFSKKVKNgvysQLscptayegVSLSKNTSGVCVAGNGDNymiteslndskvVDIHGYEVNWQ 752
Cdd:COG4772  482 ELGTRGRIGNGLSAEVALFYIDYDN----EL--------GSCSAAGGDRSTFTNAGE------------TRHQGLELALD 537

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 753 QSLDAWlPINGFGLIANYTHVN------PAQSTTGFRLANLSEHTANGTLYWENQTFSARLSANYRSAYdQTSVESFFAG 826
Cdd:COG4772  538 YDLLKG-GGLGLPLFAAYTYTDaeftsdFGPVFAGNRLPYVPRHQLTAGLGYEHGGWTANLNGRYVSEQ-FTDAANTVAD 615

                        810       820       830       840
                 ....*....|....*....|....*....|....*....|....*.
gi 295432407 827 PLGHTVKSRTQLDLNLGYNFNEHLSFAFaamNINNAQEEAYLGNSS 872
Cdd:COG4772  616 GSFGKIPSYTVLDLSASYDFGKNLSLFA---GVNNLFDKRYIASRA 658
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 46-173 2.10e-08

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 57.97  E-value: 2.10e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  46 DEVIVTAfrkslaTALEVKRKDVRVS-DGISSEDIGKFPSENIAEAIQRIPGVQISNINGRGSTISIRGLGPQYALTTVN 124
Cdd:PRK10064  31 ETMVVTA------SAVEQNLKDAPASiSVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLILID 104

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 295432407 125 GQAFKSSNFT---DGFRYDVIQTELASGIQVYKSPTAEM---DAggLAGTVNIDT 173
Cdd:PRK10064 105 GKRVNSRNAVfrhNDFDLNWIPVDAIERIEVVRGPMSSLygsDA--LGGVVNIIT 157
PRK13513 PRK13513
ligand-gated channel protein;
660-851 8.06e-08

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 55.93  E-value: 8.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 660 GQGNLDPMTANQLDLTLEWYYGQGNGLSAGYFSKKVKNGVYSQLSCPTayegvslsKNTSGVCVAgNGDNY-MITESLND 738
Cdd:PRK13513 447 GNSDLKPEKSISQEIGILWDNQENLNASVTLFNTDFKDKITEVRNCDT--------TNTDGQCVF-NGINYdFISDRINV 517

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 739 SKVvDIHGYEV--NWQQSlDAWlpingfGLIANYTHVNPAQSTTGFR---LANLSEHTANGTLYWE-NQTFSARLSANYR 812
Cdd:PRK13513 518 DKA-NMRGVEAtfNWDIN-QAW------SLATNYTFTQSEQKSGAFAgqpLNQMPKHMANATLNWQtTEDFATWIRINYR 589

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 295432407 813 SaydQTSvESFFAGPLGHTVKSRTQLDLNLGYNFNEHLS 851
Cdd:PRK13513 590 G---KTS-EYLNRTSMGSGTPSYTFVDLGASYQLTKELR 624
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 57-179 5.46e-06

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 50.14  E-value: 5.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  57 LATALEVKRKDVRVSDgISSEDIGKFPSEN-IAEAIQRIPGVQI-----SNINGRGSTISIRGLGPQYALTTVNGQAFKS 130
Cdd:PRK13528  40 EATAEQELKQQPGVSI-ITAEDIKKRPPVNdLSDIIRKMPGVNLtgnsaSGTRGNNRQIDIRGMGPENTLILIDGVPVTS 118

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 295432407 131 SNftdGFRY------------DVIQTELASGIQVYKSP-TAEMDAGGLAGTVNIDTVHPFDV 179
Cdd:PRK13528 119 RN---SVRYswrgerdtrgdtNWVPPEMVERIEVIRGPaAARYGSGAAGGVVNIITKRPTND 177
OMP_b-brl_3 pfam14905
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ...
 534-892 6.94e-06

Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.


Pssm-ID: 434300 [Multi-domain]  Cd Length: 407  Bit Score: 49.58  E-value: 6.94e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  534 YRVERDLTSFYAMANLKGevlsKTFRGNVGVRSESTDQTIDgyiggaanplntevkLVAGTYTAKKSYDNILPSANFSLD 613
Cdd:pfam14905 108 FDYKENIYAAYASYSKKF----GKWSYQAGLRAEYTDIDGD---------------SVTTNETFKRNYFNLFPSASLSYK 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  614 LTDN--LLLRVAAAKVLVRPiidSSNQLARTMTSTTDTsgvkvfTISTGQGNLDPMTANQLDLTlewyYGQGNGLSAGYF 691
Cdd:pfam14905 169 LNDNnsLQLSLYYRRIINRP---SYWDLNPFRNYSDPY------NYSQGNPNLKPEYTNSFELG----YTYKWKLSLSLS 235

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  692 SKKVKNgvysqlscptayegvslskNTSGVCVAGNGDNYMITESLNDSKvVDIHGYEVNWQQSLDAWLPING-FGLIANY 770
Cdd:pfam14905 236 YRYTND-------------------VIQQTFITDDNDNVTYTTYENLGK-SNSYGLELSASFNPTKWWSLNGnLNGYYNK 295

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  771 THVNpaqsttgfrlANLSEHTANGTLYW-------ENQTFSARLSANYRSAYDQTSVEsffagplghtVKSRTQLDLNLG 843
Cdd:pfam14905 296 YKID----------GSLNSDFSNFGFNWnlnntftLPKGWSLQLNGNYRSPRVTGQGK----------IKPFYSLDLGLS 355

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 295432407  844 YNF-NEHLSFAFaamNINNaqeeayLGNSSRWQETSVTGPSYYLSFQYKM 892
Cdd:pfam14905 356 KSFlKKKLTLSL---NVND------IFNTRKFRSTTNYDNGFIQSYNNKW 396
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
74-224 8.97e-05

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 46.15  E-value: 8.97e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  74 ISSEDIGKFPSENIAEAIQRIPGVQIsNINGRGSTISIRGLGPQYALTTVNG--QAFKSS--NFTDGFRYDVI-QTELAS 148
Cdd:PRK13484  54 ITSEQLQKKPVSDLVDAVKDVEGISI-TGGNEKPDISIRGLSGDYTLILVDGrrQSGRESrpNGSGGFEAGFIpPVEAIE 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407 149 GIQVYKSPTAEM---DAGGlaGTVNIDTvHPFDVKGRQ--IILAGKLQKQDLVGGDPTGKYGLTyvDHFLDGKLGVFLGG 223
Cdd:PRK13484 133 RIEVIRGPMSSLygsDAIG--GVINIIT-KPVNNQTWDgvLGLGGIIQEHGKFGNSTTNDFYLS--GPLIKDKLGLQLYG 207


                 .
gi 295432407 224 G 224
Cdd:PRK13484 208 G 208
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
15-176 6.99e-04

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 43.48  E-value: 6.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  15 AFTLALLGGVCFADMALAQAAPAPAAEPEavDEVIVTAFRKSL-ATALEVkrkdvrvsdgISSEDIGKFPSEN-IAEAIQ 92
Cdd:PRK13524  10 LLVNLGIYGVAQAAEAEDAKTDDTPASHE--DTIVVTAAEQNLqAPGVST----------ITAEDIRKRPPANdVSEIIR 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295432407  93 RIPGVQI---SNINGRGST--ISIRGLGPQYALTTVNGQAFKSSNftdGFRY------------DVIQTELASGIQVYKS 155
Cdd:PRK13524  78 TMPGVNLtgnSTSGQRGNNrqIDIRGMGPENTLILIDGKPVSSRN---SVRYgwrgerdtrgdtNWVPPEMIERIEVLRG 154

                        170       180
                 ....*....|....*....|..
gi 295432407 156 PTAEMDAGGLA-GTVNIDTVHP 176
Cdd:PRK13524 155 PAAARYGNGAAgGVVNIITKKP 176
PRK13513 PRK13513
ligand-gated channel protein;
74-126 3.91e-03

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 40.91  E-value: 3.91e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 295432407  74 ISSEDIGKFPSENIAEAIQRIPGVQISNiNGRGSTISIRGLGPQYALTTVNGQ 126
Cdd:PRK13513  59 VTREQLENKAYRDVTDALKDVPGVVVTG-GGSTSDISIRGMAAKYTLILVDGK 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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