NCBI Conserved Domain Search

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

7-527

2.35e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 80.75 E-value: 2.35e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   7 QRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQK 86
Cdd:COG1196  235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  87 LAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKE 166
Cdd:COG1196  315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 167 TVQSKDFKLEV--------DKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESR 238
Cdd:COG1196  395 AAELAAQLEELeeaeeallERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 239 LEKTEITLKDDLTKLKTLTVMLVDERKTMSE--------KLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSK 310
Cdd:COG1196  475 LEAALAELLEELAEAAARLLLLLEAEADYEGflegvkaaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE 554

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 311 TDAEEKMY-SVTKERDDLR------NKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENN 383
Cdd:COG1196  555 DDEVAAAAiEYLKAAKAGRatflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 384 KIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFR 463
Cdd:COG1196  635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 295424124 464 RLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSLLQK-KLNQQENRNRDLGREIENL 527
Cdd:COG1196  715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpDLEELERELERLEREIEAL 779

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

92-436

2.97e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 80.50 E-value: 2.97e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    92 RQIDELEETNRSLRKAEEELQDIKDKINKgeygnsgIMDEVDELRKRVLDMEGKDEELIKMEEQcrdLNKRLEKETVQSK 171
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRR-------IENRLDELSQELSDASRKIGEIEKEIEQ---LEQEEEKLKERLE 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   172 DFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKE--KMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDD 249
Cdd:TIGR02169  741 ELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAlnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQK 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   250 LTKLKTLTVMLVDERKTMSEKLKQTEDKLQSttsqLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRN 329
Cdd:TIGR02169  821 LNRLTLEKEYLEKEIQELQEQRIDLKEQIKS----IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   330 KLKAEEEKGHDLLSKVTILKNRLQSLEAieKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDL 409
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKA--KLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVN 974

                          330       340
                   ....*....|....*....|....*..
gi 295424124   410 MKTEDEYETLERRYANERDKAQFLSQE 436
Cdd:TIGR02169  975 MLAIQEYEEVLKRLDELKEKRAKLEEE 1001

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

4-531

1.66e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 71.69 E-value: 1.66e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     4 DEQQRLTAQLALQRQKIQALTTsakETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQL 83
Cdd:pfam15921  253 ESQNKIELLLQQHQDRIEQLIS---EHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQL 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    84 RQKLAALSRQI-DELEETNRSLRKAEEELQDIKDKINKGEYgNSGIMDevDELRKRVLDMEGKDEELIKMEEQCRDLNKR 162
Cdd:pfam15921  330 RSELREAKRMYeDKIEELEKQLVLANSELTEARTERDQFSQ-ESGNLD--DQLQKLLADLHKREKELSLEKEQNKRLWDR 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   163 LEKETVQSKDFKLEVDKLSVRITALEKLEDALdksKQECYSL-----------KCNLEKEKMTTKQLSEELESLNARIKE 231
Cdd:pfam15921  407 DTGNSITIDHLRRELDDRNMEVQRLEALLKAM---KSECQGQmerqmaaiqgkNESLEKVSSLTAQLESTKEMLRKVVEE 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   232 LEAIESRLEKTEITLKD-----------------DLTKLKTltvmLVDERKTMSEKLKQTEDKLQSTTSQLQA------E 288
Cdd:pfam15921  484 LTAKKMTLESSERTVSDltaslqekeraieatnaEITKLRS----RVDLKLQELQHLKNEGDHLRNVQTECEAlklqmaE 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   289 QNKVTTVTEKLIEETKRALKSKTDAEEKMY----SVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEaiekdFVK 364
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQvekaQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE-----LEK 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   365 NKLNQDSSKSTAAlhqennkIKELSQEVENLklkLKDMKAIEDDLMKTEDEYETLERRYANErdkaqflSQELEhakMEL 444
Cdd:pfam15921  635 VKLVNAGSERLRA-------VKDIKQERDQL---LNEVKTSRNELNSLSEDYEVLKRNFRNK-------SEEME---TTT 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   445 AKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEKIheyMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREI 524
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQI---TAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEK 771


                   ....*..
gi 295424124   525 ENLTKEL 531
Cdd:pfam15921  772 NKLSQEL 778

PspC_subgroup_1

NF033838

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...

40-459

1.97e-04

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.

Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 45.00 E-value: 1.97e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  40 RAQEEEQK-ATRLEKELQTQTTEFHQNQDKimakltNEDSQNRQLRQKLAALSRQIdeLEETNRSLRKAEEEL-QDIKDK 117
Cdd:NF033838  51 SGNESQKEhAKEVESHLEKILSEIQKSLDK------RKHTQNVALNKKLSDIKTEY--LYELNVLKEKSEAELtSKTKKE 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 118 INKGeygNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRlEKETVQSKDFKLEVDKLSVRITalekledaldKS 197
Cdd:NF033838 123 LDAA---FEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQKEEDRR-NYPTNTYKTLELEIAESDVEVK----------KA 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 198 KQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDL-TKLKTLTVMLVD--ERKTMSEKLKQ- 273
Cdd:NF033838 189 ELELVKEEAKEPRDEEKIKQAKAKVESKKAEATRLEKIKTDREKAEEEAKRRAdAKLKEAVEKNVAtsEQDKPKRRAKRg 268

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 274 ------TEDKlqsttSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKerddlrnklKAEEEKGHDLLSKVTI 347
Cdd:NF033838 269 vlgepaTPDK-----KENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKK---------KAKDQKEEDRRNYPTN 334

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 348 LKNRLQsLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEyetlERRYANER 427
Cdd:NF033838 335 TYKTLE-LEIAESDVKVKEAELELVKEEAKEPRNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEEE----AKRKAAEE 409

                        410       420       430
                 ....*....|....*....|....*....|..
gi 295424124 428 DKAQFLSQELEHAKMELAKYKLAEKTESSHEQ 459
Cdd:NF033838 410 DKVKEKPAEQPQPAPAPQPEKPAPKPEKPAEQ 441

Name

Accession

Description

Interval

E-value

PRK03918

DNA double-strand break repair ATPase Rad50;

12-488

9.98e-18

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 88.58 E-value: 9.98e-18

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  12 QLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLE--KELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAA 89
Cdd:PRK03918 246 ELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEING 325

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  90 LSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNS------GIMDEVDELRKRVldmegKDEELIKMEEQCRDLNKRL 163
Cdd:PRK03918 326 IEERIKELEEKEERLEELKKKLKELEKRLEELEERHElyeeakAKKEELERLKKRL-----TGLTPEKLEKELEELEKAK 400

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 164 EKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNL--EKEKMTTKQLSEELESLNARIKELEAIESRLEK 241
Cdd:PRK03918 401 EEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELteEHRKELLEEYTAELKRIEKELKEIEEKERKLRK 480

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 242 TEITLKDDLTKLKTLTVMlvderKTMSEKLKQTEDKLQS-TTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMySV 320
Cdd:PRK03918 481 ELRELEKVLKKESELIKL-----KELAEQLKELEEKLKKyNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLE-EL 554

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 321 TKERDDLRNKLKAEEEKGHDLLSK--------VTILKNRLQSLEAIEKDFVKNKlnqdsskstAALHQENNKIKELSQEV 392
Cdd:PRK03918 555 KKKLAELEKKLDELEEELAELLKEleelgfesVEELEERLKELEPFYNEYLELK---------DAEKELEREEKELKKLE 625

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 393 ENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAqfLSQELEHAKMELAKyKLAEKTEssheqwLFRRLQEEEAKS 472
Cdd:PRK03918 626 EELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEE--LREEYLELSRELAG-LRAELEE------LEKRREEIKKTL 696

                        490
                 ....*....|....*.
gi 295424124 473 GHLSREVDALKEKIHE 488
Cdd:PRK03918 697 EKLKEELEEREKAKKE 712

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

7-527

2.35e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 80.75 E-value: 2.35e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   7 QRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQK 86
Cdd:COG1196  235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  87 LAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKE 166
Cdd:COG1196  315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 167 TVQSKDFKLEV--------DKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESR 238
Cdd:COG1196  395 AAELAAQLEELeeaeeallERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 239 LEKTEITLKDDLTKLKTLTVMLVDERKTMSE--------KLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSK 310
Cdd:COG1196  475 LEAALAELLEELAEAAARLLLLLEAEADYEGflegvkaaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVE 554

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 311 TDAEEKMY-SVTKERDDLR------NKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENN 383
Cdd:COG1196  555 DDEVAAAAiEYLKAAKAGRatflplDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA 634

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 384 KIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFR 463
Cdd:COG1196  635 ALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE 714

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 295424124 464 RLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSLLQK-KLNQQENRNRDLGREIENL 527
Cdd:COG1196  715 ERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpDLEELERELERLEREIEAL 779

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

92-436

2.97e-15

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 80.50 E-value: 2.97e-15

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    92 RQIDELEETNRSLRKAEEELQDIKDKINKgeygnsgIMDEVDELRKRVLDMEGKDEELIKMEEQcrdLNKRLEKETVQSK 171
Cdd:TIGR02169  671 SEPAELQRLRERLEGLKRELSSLQSELRR-------IENRLDELSQELSDASRKIGEIEKEIEQ---LEQEEEKLKERLE 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   172 DFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKE--KMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDD 249
Cdd:TIGR02169  741 ELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAlnDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQK 820

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   250 LTKLKTLTVMLVDERKTMSEKLKQTEDKLQSttsqLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRN 329
Cdd:TIGR02169  821 LNRLTLEKEYLEKEIQELQEQRIDLKEQIKS----IEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   330 KLKAEEEKGHDLLSKVTILKNRLQSLEAieKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDL 409
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKA--KLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVN 974

                          330       340
                   ....*....|....*....|....*..
gi 295424124   410 MKTEDEYETLERRYANERDKAQFLSQE 436
Cdd:TIGR02169  975 MLAIQEYEEVLKRLDELKEKRAKLEEE 1001

PRK03918

DNA double-strand break repair ATPase Rad50;

18-532

4.79e-15

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 79.72 E-value: 4.79e-15

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  18 QKIQALTTSAKETQGKLALAEARAQEEEQKATRLEkELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALS---RQI 94
Cdd:PRK03918 207 REINEISSELPELREELEKLEKEVKELEELKEEIE-ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEekvKEL 285

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  95 DELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELikmeeqcRDLNKR---LEKETVQSK 171
Cdd:PRK03918 286 KELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERL-------EELKKKlkeLEKRLEELE 358

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 172 DFKLEVDKLSVRITALEKLEDAL-DKSKQECYSLKCNLEKEKmttKQLSEELESLNARIKELEAIESRLEKTEITLKDDL 250
Cdd:PRK03918 359 ERHELYEEAKAKKEELERLKKRLtGLTPEKLEKELEELEKAK---EEIEEEISKITARIGELKKEIKELKKAIEELKKAK 435

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 251 TKLKTLTVMLVDERK-----TMSEKLKQTEDKLQSTTSQLQAEQNKVTTVtEKLIEETKRALKSKT------DAEEKMYS 319
Cdd:PRK03918 436 GKCPVCGRELTEEHRkelleEYTAELKRIEKELKEIEEKERKLRKELREL-EKVLKKESELIKLKElaeqlkELEEKLKK 514

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 320 VTKErddlrnKLKAEEEKGHDLLSKVTILKNRLQSLeaiEKDFvkNKLNQDSSKSTAAlhqeNNKIKELSQEVENLKLKL 399
Cdd:PRK03918 515 YNLE------ELEKKAEEYEKLKEKLIKLKGEIKSL---KKEL--EKLEELKKKLAEL----EKKLDELEEELAELLKEL 579

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 400 KDMK-AIEDDLMKTEDEYETLERRYANERDKAQFLSQELEhaKMELAKYKLAEKtessheqwlFRRLQEEEAKSGHLSRE 478
Cdd:PRK03918 580 EELGfESVEELEERLKELEPFYNEYLELKDAEKELEREEK--ELKKLEEELDKA---------FEELAETEKRLEELRKE 648

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 295424124 479 VDALKEKI--HEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELE 532
Cdd:PRK03918 649 LEELEKKYseEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

5-535

2.78e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 77.40 E-value: 2.78e-14

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     5 EQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEK---ELQTQTTEFHQNQDKIMAKLTNEDSQNR 81
Cdd:TIGR02168  296 EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEkleELKEELESLEAELEELEAELEELESRLE 375

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    82 QLRQKLAALSRQIDELEETNRSLRK----AEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDM--EGKDEELIKMEEQ 155
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNeierLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAelEELEEELEELQEE 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   156 CRDLNKRLEKETVQSK-------DFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEEL------ 222
Cdd:TIGR02168  456 LERLEEALEELREELEeaeqaldAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIsvdegy 535

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   223 -----------------ESLNARIKELEA---------------------IESRLEKTEITLKDDLTKLKTLTVMLVDER 264
Cdd:TIGR02168  536 eaaieaalggrlqavvvENLNAAKKAIAFlkqnelgrvtflpldsikgteIQGNDREILKNIEGFLGVAKDLVKFDPKLR 615

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   265 KTMSEKLKQTE--DKLQSTTSQLQAEQNKVTTVTE--KLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHD 340
Cdd:TIGR02168  616 KALSYLLGGVLvvDDLDNALELAKKLRPGYRIVTLdgDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE 695

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   341 LLSKVTILKNRLQSLEAIEKDfvknkLNQDSSKSTAALHQENNKIKELSQEVENLklkLKDMKAIEDDLMKTEDEYETLE 420
Cdd:TIGR02168  696 LEKALAELRKELEELEEELEQ-----LRKELEELSRQISALRKDLARLEAEVEQL---EERIAQLSKELTELEAEIEELE 767

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   421 RRYANERDKAQFLSQELEHAKMELAKYKlaektessheqwlfRRLQEEEAKSGHLSREVDALKEKIHEYMATEDlicHLQ 500
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLK--------------EELKALREALDELRAELTLLNEEAANLRERLE---SLE 830

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 295424124   501 GDHSLLQKKLNQQENRNRDLGREIENLTKELERYR 535
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELE 865

PRK03918

DNA double-strand break repair ATPase Rad50;

66-532

6.44e-14

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 76.26 E-value: 6.44e-14

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  66 QDKIMAKLTNEDSQNRQLRQKLaalsrQIDELEetnrslrKAEEELQDIKDKINKgeygnsgimdEVDELRKRVLDMEGK 145
Cdd:PRK03918 134 QGEIDAILESDESREKVVRQIL-----GLDDYE-------NAYKNLGEVIKEIKR----------RIERLEKFIKRTENI 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 146 DEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESL 225
Cdd:PRK03918 192 EELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEEL 271

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 226 NARIKELEAIESRLEKTEitlkddltklktltvMLVDERKTMSEKLKQTEDKLQsttsqlqaEQNKVTTVTEKLIEETKR 305
Cdd:PRK03918 272 KKEIEELEEKVKELKELK---------------EKAEEYIKLSEFYEEYLDELR--------EIEKRLSRLEEEINGIEE 328

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 306 ALKSKTDAEEKMYSVTKERDDLRNKLkAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKI 385
Cdd:PRK03918 329 RIKELEEKEERLEELKKKLKELEKRL-EELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEI 407

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 386 KELSQEVENLKLKLKDMKAIEDDLMK------------TEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKT 453
Cdd:PRK03918 408 SKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEK 487

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 454 ESSHEQWLFRRL----QEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSLLQ---KKLNQQENRNRDLGREIEN 526
Cdd:PRK03918 488 VLKKESELIKLKelaeQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKkelEKLEELKKKLAELEKKLDE 567


                 ....*.
gi 295424124 527 LTKELE 532
Cdd:PRK03918 568 LEEELA 573

PRK03918

DNA double-strand break repair ATPase Rad50;

64-547

1.08e-13

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 75.49 E-value: 1.08e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  64 QNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKgeygnsgIMDEVDELRKRVLDME 143
Cdd:PRK03918 179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEE-------LKEEIEELEKELESLE 251

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 144 GKDEELikmEEQCRDLNKRLEKETVQSKDFK---LEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKekmttkqLSE 220
Cdd:PRK03918 252 GSKRKL---EEKIRELEERIEELKKEIEELEekvKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSR-------LEE 321

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 221 ELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLtvmlvDERKTMSEKLKQTEDKLQSTTSQLQAEQnkvttvTEKLI 300
Cdd:PRK03918 322 EINGIEERIKELEEKEERLEELKKKLKELEKRLEEL-----EERHELYEEAKAKKEELERLKKRLTGLT------PEKLE 390

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 301 EETKRALKSKTDAEEKMYSVTKERDDLRNKLKA----------------------EEEKGHDLLSKVTI----LKNRLQS 354
Cdd:PRK03918 391 KELEELEKAKEEIEEEISKITARIGELKKEIKElkkaieelkkakgkcpvcgrelTEEHRKELLEEYTAelkrIEKELKE 470

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 355 LEAIEKDFVKNKLNQDsskSTAALHQENNKIKELSQEVENLKLKLKDMKAieDDLMKTEDEYETLERRYANERDKAQFLS 434
Cdd:PRK03918 471 IEEKERKLRKELRELE---KVLKKESELIKLKELAEQLKELEEKLKKYNL--EELEKKAEEYEKLKEKLIKLKGEIKSLK 545

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 435 QELEHA-----KMELAKYKLAEKTESSHEqwLFRRLQEEEAKS-GHLSREVDALKEKIHEYMATEDlichlqgdhslLQK 508
Cdd:PRK03918 546 KELEKLeelkkKLAELEKKLDELEEELAE--LLKELEELGFESvEELEERLKELEPFYNEYLELKD-----------AEK 612

                        490       500       510
                 ....*....|....*....|....*....|....*....
gi 295424124 509 KLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNE 547
Cdd:PRK03918 613 ELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

4-340

1.59e-13

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 75.10 E-value: 1.59e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     4 DEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKltnedsqnrql 83
Cdd:TIGR02169  688 RELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV----------- 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    84 RQKLAALSRQIDELEETnrsLRKAEEELQDIKDKINKGEYGNsgIMDEVDELRKRVLDMEGKDEElIKMEEQCRDLNKRL 163
Cdd:TIGR02169  757 KSELKELEARIEELEED---LHKLEEALNDLEARLSHSRIPE--IQAELSKLEEEVSRIEARLRE-IEQKLNRLTLEKEY 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   164 EKETVQSKdfKLEVDKLSVRITALEKLEDALDKSKQEcysLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTE 243
Cdd:TIGR02169  831 LEKEIQEL--QEQRIDLKEQIKSIEKEIENLNGKKEE---LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   244 ITLKDDLTKLKTLTVMLVDERKTMSEKLKQTED----------------KLQSTTSQLQAEQNKVTTVTEKLIEETKRAL 307
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDpkgedeeipeeelsleDVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          330       340       350
                   ....*....|....*....|....*....|...
gi 295424124   308 KSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHD 340
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

3-566

3.04e-13

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.94 E-value: 3.04e-13

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     3 VDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQ-NQDKIMAKltnedSQNR 81
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRlEQQKQILR-----ERLA 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    82 QLRQKLAALSRQIDELEetnRSLRKAEEELQDIKDKINkgeygnsGIMDEVDELRKRVLDMEGKDEElikMEEQCRDLNK 161
Cdd:TIGR02168  313 NLERQLEELEAQLEELE---SKLDELAEELAELEEKLE-------ELKEELESLEAELEELEAELEE---LESRLEELEE 379

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   162 RLEKETVQSKDFKLEVDKLSVRITALEK----LEDALDKSKQECYSLKCNLEKEKMttKQLSEELESLNARIKELEAIES 237
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEArlerLEDRRERLQQEIEELLKKLEEAEL--KELQAELEELEEELEELQEELE 457

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   238 RLEKTEITLKDDLTKLKTLTVMLVDE------RKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIE------ETKR 305
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERElaqlqaRLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSElisvdeGYEA 537

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   306 AL-------------KSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVK-------- 364
Cdd:TIGR02168  538 AIeaalggrlqavvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKfdpklrka 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   365 ---------------------NKLNQDSSKSTAALH-------------QENNKIKELSQEVENLKLKLKDMKAIEDDLM 410
Cdd:TIGR02168  618 lsyllggvlvvddldnalelaKKLRPGYRIVTLDGDlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   411 KTEDEYETLERRYANERDKAQFLSQELEHAKMELakYKLAEKTESSHEQWLfRRLQEEEAKSGHLSREVDALKEKIHEym 490
Cdd:TIGR02168  698 KALAELRKELEELEEELEQLRKELEELSRQISAL--RKDLARLEAEVEQLE-ERIAQLSKELTELEAEIEELEERLEE-- 772

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 295424124   491 aTEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKEL--ERYRHFSKSLRPSLNERRISDPQVFSKEVQTEAAD 566
Cdd:TIGR02168  773 -AEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELtlLNEEAANLRERLESLERRIAATERRLEDLEEQIEE 849

PRK02224

DNA double-strand break repair Rad50 ATPase;

16-358

7.35e-13

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 72.77 E-value: 7.35e-13

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  16 QRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMA-----------------KLTNEDS 78
Cdd:PRK02224 333 CRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEEleeeieelrerfgdapvDLGNAED 412

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  79 QNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYG----NSGIMDEVDELRKRVLDMEgkdEELIKMEE 154
Cdd:PRK02224 413 FLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGqpveGSPHVETIEEDRERVEELE---AELEDLEE 489

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 155 QCRDLNKRLE--KETVQSKDfklEVDKLSVRITALEKL----EDALDKSKQECYSLK---------------------CN 207
Cdd:PRK02224 490 EVEEVEERLEraEDLVEAED---RIERLEERREDLEELiaerRETIEEKRERAEELReraaeleaeaeekreaaaeaeEE 566

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 208 LEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEiTLKDDLTKLKtltvmlvDERKTMSEKLKQTEDKLQST---TSQ 284
Cdd:PRK02224 567 AEEAREEVAELNSKLAELKERIESLERIRTLLAAIA-DAEDEIERLR-------EKREALAELNDERRERLAEKrerKRE 638

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424124 285 LQAEQNKvtTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNK---LKAEEEKGHDLLSKVTILKNRLQSLEAI 358
Cdd:PRK02224 639 LEAEFDE--ARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELEELRERREALENRVEALEAL 713

PTZ00121

MAEBL; Provisional

14-488

9.99e-13

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 72.48 E-value: 9.99e-13

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   14 ALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMA--KLTNEDSQNRQLRQKLAALS 91
Cdd:PTZ00121 1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAaeKKKEEAKKKADAAKKKAEEK 1390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   92 RQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMD--EVDELRKRVLDMEGKDEELIKMEEqcrdlnKRLEKETVQ 169
Cdd:PTZ00121 1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkkKADEAKKKAEEAKKADEAKKKAEE------AKKAEEAKK 1464

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  170 SKDFKLEVDKLSVRITALEKLEDAldKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDD 249
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEA--KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKA 1542

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  250 LTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTtvteKLIEETKRALKSKTDAEEKMYSVTKERDDLRN 329
Cdd:PTZ00121 1543 EEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA----KKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  330 KLKAEEekghdlLSKVTILKNRLQSLEAIEKDFVKN--KLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIED 407
Cdd:PTZ00121 1619 KIKAEE------LKKAEEEKKKVEQLKKKEAEEKKKaeELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAE 1692

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  408 DLMKTEDE---YETLERRYANERDKAQFLSQELE--HAKMELAKYKLAEKTESSHEqwlFRRLQEEEAKSGHLSREVDAL 482
Cdd:PTZ00121 1693 ALKKEAEEakkAEELKKKEAEEKKKAEELKKAEEenKIKAEEAKKEAEEDKKKAEE---AKKDEEEKKKIAHLKKEEEKK 1769


                  ....*.
gi 295424124  483 KEKIHE 488
Cdd:PTZ00121 1770 AEEIRK 1775

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

4-531

1.66e-12

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 71.69 E-value: 1.66e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     4 DEQQRLTAQLALQRQKIQALTTsakETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQL 83
Cdd:pfam15921  253 ESQNKIELLLQQHQDRIEQLIS---EHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQL 329

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    84 RQKLAALSRQI-DELEETNRSLRKAEEELQDIKDKINKGEYgNSGIMDevDELRKRVLDMEGKDEELIKMEEQCRDLNKR 162
Cdd:pfam15921  330 RSELREAKRMYeDKIEELEKQLVLANSELTEARTERDQFSQ-ESGNLD--DQLQKLLADLHKREKELSLEKEQNKRLWDR 406

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   163 LEKETVQSKDFKLEVDKLSVRITALEKLEDALdksKQECYSL-----------KCNLEKEKMTTKQLSEELESLNARIKE 231
Cdd:pfam15921  407 DTGNSITIDHLRRELDDRNMEVQRLEALLKAM---KSECQGQmerqmaaiqgkNESLEKVSSLTAQLESTKEMLRKVVEE 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   232 LEAIESRLEKTEITLKD-----------------DLTKLKTltvmLVDERKTMSEKLKQTEDKLQSTTSQLQA------E 288
Cdd:pfam15921  484 LTAKKMTLESSERTVSDltaslqekeraieatnaEITKLRS----RVDLKLQELQHLKNEGDHLRNVQTECEAlklqmaE 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   289 QNKVTTVTEKLIEETKRALKSKTDAEEKMY----SVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEaiekdFVK 364
Cdd:pfam15921  560 KDKVIEILRQQIENMTQLVGQHGRTAGAMQvekaQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLE-----LEK 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   365 NKLNQDSSKSTAAlhqennkIKELSQEVENLklkLKDMKAIEDDLMKTEDEYETLERRYANErdkaqflSQELEhakMEL 444
Cdd:pfam15921  635 VKLVNAGSERLRA-------VKDIKQERDQL---LNEVKTSRNELNSLSEDYEVLKRNFRNK-------SEEME---TTT 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   445 AKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEKIheyMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREI 524
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQI---TAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEK 771


                   ....*..
gi 295424124   525 ENLTKEL 531
Cdd:pfam15921  772 NKLSQEL 778

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

81-448

2.10e-12

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 71.24 E-value: 2.10e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    81 RQLRQKLAALSRQIDELEETNRSLRKAE------EELQDIKDKINKGEYGNSGimDEVDELRKRvldMEGKDEELIKMEE 154
Cdd:TIGR02168  179 RKLERTRENLDRLEDILNELERQLKSLErqaekaERYKELKAELRELELALLV--LRLEELREE---LEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   155 QCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALdkskqecYSLKCNLEKEKMttkQLSEELESLNARIKELEA 234
Cdd:TIGR02168  254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL-------ANEISRLEQQKQ---ILRERLANLERQLEELEA 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   235 IESRLEKTEITLKDDLTKLktltvmlvderktmseklkqtEDKLQSTTSQLQAEQNKVTTVTEKLIEetkralksktdAE 314
Cdd:TIGR02168  324 QLEELESKLDELAEELAEL---------------------EEKLEELKEELESLEAELEELEAELEE-----------LE 371

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   315 EKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEaiekdfvKNKLNQDSSKSTAALHQENNKIKELSQEVEN 394
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE-------DRRERLQQEIEELLKKLEEAELKELQAELEE 444

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 295424124   395 LKLKLKDmkaieddlmkTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYK 448
Cdd:TIGR02168  445 LEEELEE----------LQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

94-468

2.29e-12

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 71.25 E-value: 2.29e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    94 IDEL---EETNRSLRKAEEELQDIKDKINKGEygnsgIMdeVDELRKRVLDMEGKDEELIKMEEQcrdlnkRLEKETVQS 170
Cdd:TIGR02169  159 IDEIagvAEFDRKKEKALEELEEVEENIERLD-----LI--IDEKRQQLERLRREREKAERYQAL------LKEKREYEG 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   171 KDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEkmtTKQLSEELESLNARIKELEAIESRLEKTEI-TLKDD 249
Cdd:TIGR02169  226 YELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKR---LEEIEQLLEELNKKIKDLGEEEQLRVKEKIgELEAE 302

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   250 LTKLKTLTVMLVDERKTMSEKLKQTE---DKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDD 326
Cdd:TIGR02169  303 IASLERSIAEKERELEDAEERLAKLEaeiDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   327 LRNKLKAEEEKGHDLLSKVTILKNRLQSLEAiekdfVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLkdmKAIE 406
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQE-----ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEI---KKQE 454

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 295424124   407 DDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKyKLAEKTESSHEQWLFRRLQEE 468
Cdd:TIGR02169  455 WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE-AEAQARASEERVRGGRAVEEV 515

PTZ00121

MAEBL; Provisional

38-559

2.41e-12

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 71.33 E-value: 2.41e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   38 EARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKlaalsRQIDELEETnRSLRKAEEELQDIKDK 117
Cdd:PTZ00121 1241 EAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEK-----KKADEAKKA-EEKKKADEAKKKAEEA 1314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  118 INKGEygnsgIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDfKLEVDKLsvRITALEKLEDALDKS 197
Cdd:PTZ00121 1315 KKADE-----AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE-KAEAAEK--KKEEAKKKADAAKKK 1386

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  198 KQECYSLKcNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEitlKDDLTKLKTltvmlvDERKTMSEKLKQTEDK 277
Cdd:PTZ00121 1387 AEEKKKAD-EAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKK---KADEAKKKA------EEAKKADEAKKKAEEA 1456

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  278 LQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEA 357
Cdd:PTZ00121 1457 KKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKA 1536

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  358 IEKDFVKNKLNQDSSKSTAALH--QENNKIKELSQEVENLKLKLK---DMKAIE----DDLMKTEDEYETLE----RRYA 424
Cdd:PTZ00121 1537 DEAKKAEEKKKADELKKAEELKkaEEKKKAEEAKKAEEDKNMALRkaeEAKKAEeariEEVMKLYEEEKKMKaeeaKKAE 1616

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  425 NERDKAQFLSQElEHAKMELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEKIHEYMATEDlichlqgdhs 504
Cdd:PTZ00121 1617 EAKIKAEELKKA-EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE---------- 1685

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 295424124  505 lLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNERRISDPQVFSKE 559
Cdd:PTZ00121 1686 -DEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA 1739

PTZ00121

MAEBL; Provisional

17-563

3.94e-12

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 70.56 E-value: 3.94e-12

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   17 RQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEfhqnqdkIMAKLTNEDSQNRQLRQKLAALSRQIDE 96
Cdd:PTZ00121 1261 RMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKAD-------EAKKKAEEAKKADEAKKKAEEAKKKADA 1333

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   97 LEETNRSLRKAEE----ELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEqcrdLNKRLEKEtvqskd 172
Cdd:PTZ00121 1334 AKKKAEEAKKAAEaakaEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADE----AKKKAEED------ 1403

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  173 fKLEVDKLSVRITALEKLEDALDKSKQEcysLKCNLEKEKMTTKQLSEELESlnaRIKELEAIESRLEKTEITLKDDLTK 252
Cdd:PTZ00121 1404 -KKKADELKKAAAAKKKADEAKKKAEEK---KKADEAKKKAEEAKKADEAKK---KAEEAKKAEEAKKKAEEAKKADEAK 1476

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  253 LKTLTVMLVDERKTMSEKLKQTEDKLQsttsqlQAEQNKVTTVTEKLIEETKRALKSKTdAEEKmysvtKERDDLRnklK 332
Cdd:PTZ00121 1477 KKAEEAKKADEAKKKAEEAKKKADEAK------KAAEAKKKADEAKKAEEAKKADEAKK-AEEA-----KKADEAK---K 1541

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  333 AEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEV-ENLKLKLKDMKAIEDDLMK 411
Cdd:PTZ00121 1542 AEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYeEEKKMKAEEAKKAEEAKIK 1621

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  412 TED---------EYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSRE---- 478
Cdd:PTZ00121 1622 AEElkkaeeekkKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEaeea 1701

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  479 --VDALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNERRISDPQVF 556
Cdd:PTZ00121 1702 kkAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI 1781


                  ....*..
gi 295424124  557 SKEVQTE 563
Cdd:PTZ00121 1782 EEELDEE 1788

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

14-337

5.77e-12

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 70.09 E-value: 5.77e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    14 ALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTnedsQNRQLRQKLAALSRQ 93
Cdd:TIGR02168  666 AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSR----QISALRKDLARLEAE 741

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    94 IDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVldmegkDEELIKMEEQCRDLNKRLEKETVQSKDF 173
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL------EAQIEQLKEELKALREALDELRAELTLL 815

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   174 KLEVDKLSVRITALEKLEDALDKSKQEcyslkcnLEKEKmttKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKL 253
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATERRLED-------LEEQI---EELSEDIESLAAEIEELEELIEELESELEALLNERASL 885

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   254 KTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKL------IEETKRALKSK-----TDAEEKMYSVTK 322
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLeglevrIDNLQERLSEEysltlEEAEALENKIED 965

                          330
                   ....*....|....*
gi 295424124   323 ERDDLRNKLKAEEEK 337
Cdd:TIGR02168  966 DEEEARRRLKRLENK 980

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

9-547

6.88e-12

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 69.71 E-value: 6.88e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     9 LTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQ-------TTEFHQNQDKIM---AKLTNEDS 78
Cdd:TIGR02169  299 LEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEErkrrdklTEEYAELKEELEdlrAELEEVDK 378

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    79 QNRQLRQKLAALSRQID----ELEETNRS-------LRKAEEELQDIKDKInkgeygnSGIMDEVDELRKRVLDmegKDE 147
Cdd:TIGR02169  379 EFAETRDELKDYREKLEklkrEINELKREldrlqeeLQRLSEELADLNAAI-------AGIEAKINELEEEKED---KAL 448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   148 ELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQecySLKCNLEKEKMTTKQLSEELESLNA 227
Cdd:TIGR02169  449 EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQAR---ASEERVRGGRAVEEVLKASIQGVHG 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   228 RIKEL--------EAIES----RLEKteITLKDDLT-----------KLKTLTVMLVDERKTMSEKLK------------ 272
Cdd:TIGR02169  526 TVAQLgsvgeryaTAIEVaagnRLNN--VVVEDDAVakeaiellkrrKAGRATFLPLNKMRDERRDLSilsedgvigfav 603

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   273 ---QTEDKLQS----------------TTSQLQAEQNKVT---------------TVTEKLIEETKRALKSKT-DAEEKM 317
Cdd:TIGR02169  604 dlvEFDPKYEPafkyvfgdtlvvedieAARRLMGKYRMVTlegelfeksgamtggSRAPRGGILFSRSEPAELqRLRERL 683

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   318 YSVTKERDDLRNKLKAEEEKGHDLLSKVTILKnrlQSLEAIEKDfvKNKLNQDSSKSTAALHQENNKIKELSQEVENLKL 397
Cdd:TIGR02169  684 EGLKRELSSLQSELRRIENRLDELSQELSDAS---RKIGEIEKE--IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   398 KLKDMKA----IEDDLMKTEDEYETLERRYANERDK---AQFLSQELEHAKMELAKYKLAEKTESSHEqwlfrRLQEEEA 470
Cdd:TIGR02169  759 ELKELEArieeLEEDLHKLEEALNDLEARLSHSRIPeiqAELSKLEEEVSRIEARLREIEQKLNRLTL-----EKEYLEK 833

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424124   471 KSGHLSREVDALKEKIHEYMATEDLichLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNE 547
Cdd:TIGR02169  834 EIQELQEQRIDLKEQIKSIEKEIEN---LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE 907

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

2-535

7.14e-12

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 69.70 E-value: 7.14e-12

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     2 VVDEQQRLTAQLALQRQKIQALTTSAKETqgKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNR 81
Cdd:TIGR02168  380 QLETLRSKVAQLELQIASLNNEIERLEAR--LERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELE 457

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    82 QLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDE---ELIKMEEQCR- 157
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGvlsELISVDEGYEa 537

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   158 ----DLNKRLEKETVQSKD-FKLEVDKL--------------SVRITALEKLEDALDKSKQECYSLKCNLEKekmTTKQL 218
Cdd:TIGR02168  538 aieaALGGRLQAVVVENLNaAKKAIAFLkqnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVK---FDPKL 614

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   219 SEELESLNARIKELEAIESRLEK--------TEITLKDDL-------TKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTS 283
Cdd:TIGR02168  615 RKALSYLLGGVLVVDDLDNALELakklrpgyRIVTLDGDLvrpggviTGGSAKTNSSILERRREIEELEEKIEELEEKIA 694

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   284 QLQAEQNKVTTVTEKLIEETKRALKSKTDAEekmysvtKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEkdfv 363
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELS-------RQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEI---- 763

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   364 kNKLNQDSSKSTAALHQENNKIKELSQEVENLKlklKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKME 443
Cdd:TIGR02168  764 -EELEERLEEAEEELAEAEAEIEELEAQIEQLK---EELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERR 839

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   444 LAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEkihEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGRE 523
Cdd:TIGR02168  840 LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLN---ERASLEEALALLRSELEELSEELRELESKRSELRRE 916

                          570
                   ....*....|..
gi 295424124   524 IENLTKELERYR 535
Cdd:TIGR02168  917 LEELREKLAQLE 928

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

5-448

1.21e-11

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 68.51 E-value: 1.21e-11

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    5 EQQRLTAQLALQRQKIQALTTSAKETQGKLalaearaQEEEQKATRLEKELQTQTTEFHQNQDKImaklTNEDSQNRQLR 84
Cdd:TIGR04523 226 QNNQLKDNIEKKQQEINEKTTEISNTQTQL-------NQLKDEQNKIKKQLSEKQKELEQNNKKI----KELEKQLNQLK 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   85 QKLAALSRQIDE--LEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEG----KDEELIKMEEQCRD 158
Cdd:TIGR04523 295 SEISDLNNQKEQdwNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESenseKQRELEEKQNEIEK 374

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  159 LNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEkmtTKQLSEELESLNARIKELEAIESR 238
Cdd:TIGR04523 375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE---IERLKETIIKNNSEIKDLTNQDSV 451

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  239 LEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLqaeqNKVTTVTEKLIEETKRALKSKTDAEEKMY 318
Cdd:TIGR04523 452 KELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKEL----KKLNEEKKELEEKVKDLTKKISSLKEKIE 527

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  319 SVTKERDDLRNKLKAEEEKghdLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENL--K 396
Cdd:TIGR04523 528 KLESEKKEKESKISDLEDE---LNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLikE 604

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....
gi 295424124  397 LKLKDMKA--IEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYK 448
Cdd:TIGR04523 605 IEEKEKKIssLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIR 658

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

19-324

1.48e-11

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 68.56 E-value: 1.48e-11

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    19 KIQALTTSAKETQGKLALAEARAQEEEQKAtrLEKELQTQTTEFHQNQDKImakltnedsqnRQLRQKLAALSRQIDELE 98
Cdd:TIGR02169  212 RYQALLKEKREYEGYELLKEKEALERQKEA--IERQLASLEEELEKLTEEI-----------SELEKRLEEIEQLLEELN 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    99 EtnRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGK----DEELIKMEEQCRDLNKRLEKEtvqskdfK 174
Cdd:TIGR02169  279 K--KIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERlaklEAEIDKLLAEIEELEREIEEE-------R 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   175 LEVDKLsvrITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRL--EKTEIT-----LK 247
Cdd:TIGR02169  350 KRRDKL---TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLqeELQRLSeeladLN 426

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295424124   248 DDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKL--IEETKRALKSKTDAEEKMYSVTKER 324
Cdd:TIGR02169  427 AAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYdrVEKELSKLQRELAEAEAQARASEER 505

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

3-461

7.44e-11

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 65.94 E-value: 7.44e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   3 VDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQttEFHQNQDKIMAKLTNEDSQNRQ 82
Cdd:COG4717   73 LKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL--PLYQELEALEAELAELPERLEE 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  83 LRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGN-SGIMDEVDELRKRVLDMEgkdEELIKMEEQCRDLNK 161
Cdd:COG4717  151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELE---EELEEAQEELEELEE 227

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 162 RLEKETVQSKDFKLE--VDKLSV------RITALEKLEDALDKSKQEC-----------YSLKCNLEKEKMTTKQLSEEL 222
Cdd:COG4717  228 ELEQLENELEAAALEerLKEARLllliaaALLALLGLGGSLLSLILTIagvlflvlgllALLFLLLAREKASLGKEAEEL 307

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 223 ESLNARikeleaieSRLEKTEIT-LKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQnkvttvteklIE 301
Cdd:COG4717  308 QALPAL--------EELEEEELEeLLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEE----------LE 369

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 302 ETKRALKSKTDAEekmysvtkERDDLRNKLKAEEEKgHDLLSKVTILKNRLQSL----EAIEKDFVKNKLNQDSSKSTAA 377
Cdd:COG4717  370 QEIAALLAEAGVE--------DEEELRAALEQAEEY-QELKEELEELEEQLEELlgelEELLEALDEEELEEELEELEEE 440

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 378 LHQENNKIKELSQEVENLKLKLKDMKAiEDDLMKTEDEYETLerryanerdKAQFLSQELEHAKMELAKYKLAEKTESSH 457
Cdd:COG4717  441 LEELEEELEELREELAELEAELEQLEE-DGELAELLQELEEL---------KAELRELAEEWAALKLALELLEEAREEYR 510


                 ....
gi 295424124 458 EQWL 461
Cdd:COG4717  511 EERL 514

PRK02224

DNA double-strand break repair Rad50 ATPase;

35-535

9.54e-11

DNA double-strand break repair Rad50 ATPase;

Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 65.83 E-value: 9.54e-11

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  35 ALAEARAQEEEQKatrlEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDI 114
Cdd:PRK02224 188 SLDQLKAQIEEKE----EKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDL 263

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 115 KDKINKGEYGNSGIMDEVDELRKRVLDMEGKD---------------------EELIKMEEQCRDlnkRLEKETVQSKDF 173
Cdd:PRK02224 264 RETIAETEREREELAEEVRDLRERLEELEEERddllaeaglddadaeavearrEELEDRDEELRD---RLEECRVAAQAH 340

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 174 KLEVDKLSVRITALE----KLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIK----ELEAIESRLEKTEIT 245
Cdd:PRK02224 341 NEEAESLREDADDLEeraeELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGdapvDLGNAEDFLEELREE 420

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 246 LKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKL------------IEETKRALKSKTDA 313
Cdd:PRK02224 421 RDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRerveeleaeledLEEEVEEVEERLER 500

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 314 EEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSL---------EAIEKDFVKNKLNQDSSKSTAALHQENNK 384
Cdd:PRK02224 501 AEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELreraaeleaEAEEKREAAAEAEEEAEEAREEVAELNSK 580

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 385 IKELSQEVENLklklkdmKAIEDDLMKTEDEYETLERRyaNERDKAQflsQELEHAKMElakyKLAEKTEssheqwlfRR 464
Cdd:PRK02224 581 LAELKERIESL-------ERIRTLLAAIADAEDEIERL--REKREAL---AELNDERRE----RLAEKRE--------RK 636

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295424124 465 LQEEEAKSGHLSREVDALKEKIHEYMATEDlichlqgdhsllqKKLNQQENRNRDLGREI---ENLTKELERYR 535
Cdd:PRK02224 637 RELEAEFDEARIEEAREDKERAEEYLEQVE-------------EKLDELREERDDLQAEIgavENELEELEELR 697

DUF3584

pfam12128

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...

36-537

1.26e-10

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.

Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 65.63 E-value: 1.26e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    36 LAEARAQEEEQKAT-RLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAE-EELQD 113
Cdd:pfam12128  272 TLIASRQEERQETSaELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADqEQLPS 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   114 IKDKINKGEygnsgimDEVDELRKRVLDMEGKDEELI-KMEEQCRDLNKRLEKETVQSKDFKleVDKLSVRITALEKLED 192
Cdd:pfam12128  352 WQSELENLE-------ERLKALTGKHQDVTAKYNRRRsKIKEQNNRDIAGIKDKLAKIREAR--DRQLAVAEDDLQALES 422

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   193 ALDKS--------KQECYSLKCNLEKEKMTTKQL---SEELESLNARIKELEAIESRLE---KTEITLKDDLTKLKTLtv 258
Cdd:pfam12128  423 ELREQleagklefNEEEYRLKSRLGELKLRLNQAtatPELLLQLENFDERIERAREEQEaanAEVERLQSELRQARKR-- 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   259 mlvdeRKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTK-ERDDLRNKLKAEEEK 337
Cdd:pfam12128  501 -----RDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELlHRTDLDPEVWDGSVG 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   338 GHDLLSKVTIlknRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQ-------EVENLKLKLKDMKAI----E 406
Cdd:pfam12128  576 GELNLYGVKL---DLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEqlvqangELEKASREETFARTAlknaR 652

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   407 DDLMKTEDEYETLERR----YANERDKAQFLSQELEHAKMELA---KYKLAEKTESSHE---QWLFRRLQEEEAKSGHLS 476
Cdd:pfam12128  653 LDLRRLFDEKQSEKDKknkaLAERKDSANERLNSLEAQLKQLDkkhQAWLEEQKEQKREartEKQAYWQVVEGALDAQLA 732

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 295424124   477 ReVDALKEKIHEYMATEDLICHLQGDHSLlqKKLNQQENRNRDLGREIENLTKELERYRHF 537
Cdd:pfam12128  733 L-LKAAIAARRSGAKAELKALETWYKRDL--ASLGVDPDVIAKLKREIRTLERKIERIAVR 790

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

19-545

1.36e-10

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 65.47 E-value: 1.36e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    19 KIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEdsqNRQLRQKLAALSRQI---- 94
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEE---QLRVKEKIGELEAEIasle 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    95 DELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEgkdEELIKMEEQCRDLNKRLEKEtvqSKDFK 174
Cdd:TIGR02169  308 RSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLT---EEYAELKEELEDLRAELEEV---DKEFA 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   175 LEVDKLSVRITALEKLedaldksKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEA----IESRLEKTEITLKDDL 250
Cdd:TIGR02169  382 ETRDELKDYREKLEKL-------KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkineLEEEKEDKALEIKKQE 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   251 TKLKTLTVMLVDERKTMsEKLKQTEDKLQSTTSQLQAEQNKVTTvTEKLIEETKRALKSKTD------------------ 312
Cdd:TIGR02169  455 WKLEQLAADLSKYEQEL-YDLKEEYDRVEKELSKLQRELAEAEA-QARASEERVRGGRAVEEvlkasiqgvhgtvaqlgs 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   313 ------------AEEKMYSVTKERDDLR--------------------NKLKAEE------------------------- 335
Cdd:TIGR02169  533 vgeryataievaAGNRLNNVVVEDDAVAkeaiellkrrkagratflplNKMRDERrdlsilsedgvigfavdlvefdpky 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   336 -----------------EKGHDLLSK---VTILKNRLQSLEAIEKDFVKNKLNQDSSKS-TAALHQENNKIKELSQEVEN 394
Cdd:TIGR02169  613 epafkyvfgdtlvvediEAARRLMGKyrmVTLEGELFEKSGAMTGGSRAPRGGILFSRSePAELQRLRERLEGLKRELSS 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   395 LKLKLKDMK------------------AIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKY--KLAEKTE 454
Cdd:TIGR02169  693 LQSELRRIEnrldelsqelsdasrkigEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELeaRIEELEE 772

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   455 SSHEqwlfrrLQEEEAK-----SGHLSREVDALKEKIHEYMA--------TEDLICHLQGDHSLLQKKLNQQENRNRDL- 520
Cdd:TIGR02169  773 DLHK------LEEALNDlearlSHSRIPEIQAELSKLEEEVSriearlreIEQKLNRLTLEKEYLEKEIQELQEQRIDLk 846

                          650       660       670
                   ....*....|....*....|....*....|....*...
gi 295424124   521 ------GREIENLTK-------ELERYRHFSKSLRPSL 545
Cdd:TIGR02169  847 eqiksiEKEIENLNGkkeeleeELEELEAALRDLESRL 884

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

98-445

2.27e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.57 E-value: 2.27e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  98 EETNRSLRKAEEELQDIKDkinkgeygnsgIMDEV----DELRK--------RVLDMEgkdEELIKMEEQCRDLNKRLEK 165
Cdd:COG1196  175 EEAERKLEATEENLERLED-----------ILGELerqlEPLERqaekaeryRELKEE---LKELEAELLLLKLRELEAE 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 166 ETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQEcyslkcnLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEIT 245
Cdd:COG1196  241 LEELEAELEELEAELEELEAELAELEAELEELRLE-------LEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 246 LKDDLTKLKtltvmlvDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERD 325
Cdd:COG1196  314 LEERLEELE-------EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 326 DLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDfvKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAI 405
Cdd:COG1196  387 ELLEALRAAAELAAQLEELEEAEEALLERLERLEEE--LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLEL 464

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 295424124 406 EDDLMKTEDEYETL--ERRYANERDKAQFLSQELEHAKMELA 445
Cdd:COG1196  465 LAELLEEAALLEAAlaELLEELAEAAARLLLLLEAEADYEGF 506

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

5-328

2.37e-10

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 64.69 E-value: 2.37e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     5 EQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEfhqnQDKIMAKLTNEDSQNRQLR 84
Cdd:TIGR02168  685 KIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAE----VEQLEERIAQLSKELTELE 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    85 QKLAALSRQIDELEETnrsLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEG----KDEELIKMEEQCRDLN 160
Cdd:TIGR02168  761 AEIEELEERLEEAEEE---LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanLRERLESLERRIAATE 837

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   161 KRLEKETVQSKDFKLEVDKLSVRI----TALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELE--- 233
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIeeleELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRrel 917

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   234 --------AIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKR 305
Cdd:TIGR02168  918 eelreklaQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEE 997

                          330       340
                   ....*....|....*....|...
gi 295424124   306 ALKSKTDAEEKMYSVTKERDDLR 328
Cdd:TIGR02168  998 LKERYDFLTAQKEDLTEAKETLE 1020

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

9-362

2.81e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.19 E-value: 2.81e-10

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   9 LTAQLA-LQRQKIQALTtsaketqgklaLAEARAQEEEQKATRLEKELqtqttefhqnqDKIMAKLTNEDSQNRQLRQKL 87
Cdd:COG1196  198 LERQLEpLERQAEKAER-----------YRELKEELKELEAELLLLKL-----------RELEAELEELEAELEELEAEL 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  88 AALSRQIDELEETNRSLRKAEEELQdikdkinkgeygnsgimDEVDELRKRVLDMEgkdEELIKMEEQCRDLNKRLEKET 167
Cdd:COG1196  256 EELEAELAELEAELEELRLELEELE-----------------LELEEAQAEEYELL---AELARLEQDIARLEERRRELE 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 168 VQSKDFKLEVDKLSVRITALEKLEDALDKSKQEcysLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLK 247
Cdd:COG1196  316 ERLEELEEELAELEEELEELEEELEELEEELEE---AEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 248 DDLTKLKTltvmLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDL 327
Cdd:COG1196  393 RAAAELAA----QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 295424124 328 RNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDF 362
Cdd:COG1196  469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

37-396

5.13e-10

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 63.55 E-value: 5.13e-10

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    37 AEARAQEEEQKATRLEKELQtqttEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDEL----EETNRSLRKAEEELQ 112
Cdd:TIGR02169  665 GILFSRSEPAELQRLRERLE----GLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIekeiEQLEQEEEKLKERLE 740

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   113 DIKDKINKGEYGNSGIMDEVDELRKRVLDMEgkdEELIKMEEQCRDLNKRLEKETVQSKDFKL-----EVDKLSVRITAL 187
Cdd:TIGR02169  741 ELEEDLSSLEQEIENVKSELKELEARIEELE---EDLHKLEEALNDLEARLSHSRIPEIQAELskleeEVSRIEARLREI 817

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   188 EKLEDALDKSKQECYSLKCNLE--------KEKMTTKQLSE---ELESLNARIKELEAIESRLEKTEITLKddltklktl 256
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEKEIQELQeqridlkeQIKSIEKEIENlngKKEELEEELEELEAALRDLESRLGDLK--------- 888

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   257 tvmlvDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLiEETKRALKSKTDAEEKMYSVTKERDDLRnKLKAEEE 336
Cdd:TIGR02169  889 -----KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKL-EALEEELSEIEDPKGEDEEIPEEELSLE-DVQAELQ 961

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 295424124   337 KghdllskvtiLKNRLQSLEAI------EKDFVKNKLNQDSSKStAALHQENNKIKELSQEVENLK 396
Cdd:TIGR02169  962 R----------VEEEIRALEPVnmlaiqEYEEVLKRLDELKEKR-AKLEEERKAILERIEEYEKKK 1016

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

46-412

7.49e-10

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 62.73 E-value: 7.49e-10

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   46 QKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRkaeEELQDIKDKINKGEYGN 125
Cdd:TIGR04523 303 QKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQ---RELEEKQNEIEKLKKEN 379

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  126 SGIMDEVDELRKRVLDMEGK-----------DEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDAL 194
Cdd:TIGR04523 380 QSYKQEIKNLESQINDLESKiqnqeklnqqkDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNL 459

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  195 DKS----KQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEK 270
Cdd:TIGR04523 460 DNTreslETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESK 539

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  271 LKQTEDKLQS-----TTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKV 345
Cdd:TIGR04523 540 ISDLEDELNKddfelKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKEL 619

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295424124  346 TILKNRLQSLEAIEK--DFVKNKLNQDsskstaaLHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKT 412
Cdd:TIGR04523 620 EKAKKENEKLSSIIKniKSKKNKLKQE-------VKQIKETIKEIRNKWPEIIKKIKESKTKIDDIIEL 681

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

29-369

1.82e-09

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 61.61 E-value: 1.82e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    29 ETQGKLA--LAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRK 106
Cdd:TIGR02168  206 ERQAEKAerYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   107 AEEELQDIKDKINKGeygnsgimdevdELRKRVLdmegkDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITA 186
Cdd:TIGR02168  286 LQKELYALANEISRL------------EQQKQIL-----RERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   187 LEKLEDALDKSKQECYSLKCNLEKEKmttKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTklktltvMLVDERKT 266
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEELESRL---EELEEQLETLRSKVAQLELQIASLNNEIERLEARLE-------RLEDRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   267 MSEKLKQTEDKLQSttsqlqAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVT 346
Cdd:TIGR02168  419 LQQEIEELLKKLEE------AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492

                          330       340
                   ....*....|....*....|...
gi 295424124   347 ILKNRLQSLEAIEKDFVKNKLNQ 369
Cdd:TIGR02168  493 SLERLQENLEGFSEGVKALLKNQ 515

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

4-279

6.53e-09

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 60.07 E-value: 6.53e-09

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     4 DEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQL 83
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    84 RQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELikmEEQCRDLNKRL 163
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSEL---RRELEELREKL 924

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   164 EKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMttKQLSEELESLN----ARIKELEAIESRL 239
Cdd:TIGR02168  925 AQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRL--KRLENKIKELGpvnlAAIEEYEELKERY 1002

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 295424124   240 EKTEiTLKDDLTK-LKTLTVMLVDERKTMSEKLKQTEDKLQ 279
Cdd:TIGR02168 1003 DFLT-AQKEDLTEaKETLEEAIEEIDREARERFKDTFDQVN 1042

PRK05771

V-type ATP synthase subunit I; Validated

125-438

1.13e-08

V-type ATP synthase subunit I; Validated

Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 58.79 E-value: 1.13e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 125 NSGIMdEVDELRKrvldmEGKDEELIKMEEQCRDLNKRLEK-ETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQEcys 203
Cdd:PRK05771  27 ELGVV-HIEDLKE-----ELSNERLRKLRSLLTKLSEALDKlRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEK--- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 204 lkcnLEKEkmtTKQLSEELESLNARIKELEAIESRLEKteitlkddltkLKTLTVMLVDERKtmseklkqtedklqstts 283
Cdd:PRK05771  98 ----IEKE---IKELEEEISELENEIKELEQEIERLEP-----------WGNFDLDLSLLLG------------------ 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 284 qlqaeqNKVTTVTEKLIEETKralksktdaeekmYSVTKERDDLRNKLKAEEEKGHDLLSkVTILKNRLQSLEAI--EKD 361
Cdd:PRK05771 142 ------FKYVSVFVGTVPEDK-------------LEELKLESDVENVEYISTDKGYVYVV-VVVLKELSDEVEEElkKLG 201

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424124 362 FVKNKLNqDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYetlerrYANERDKAQFLSQELE 438
Cdd:PRK05771 202 FERLELE-EEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEY------LEIELERAEALSKFLK 271

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

1-454

1.18e-08

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 59.03 E-value: 1.18e-08

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     1 MVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTtEFHQNQDKIMAKLTNEDSQn 80
Cdd:pfam01576  142 LLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEE-KGRQELEKAKRKLEGESTD- 219

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    81 rqLRQKLAALSRQIDELEEtnrSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVL----DMEGKDEELIKMEEQC 156
Cdd:pfam01576  220 --LQEQIAELQAQIAELRA---QLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISelqeDLESERAARNKAEKQR 294

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   157 RDLNKRLEketvqskdfklevdklsvritALE-KLEDALD----------KSKQECYSLKCNLEKE-KMTTKQLSE---- 220
Cdd:pfam01576  295 RDLGEELE---------------------ALKtELEDTLDttaaqqelrsKREQEVTELKKALEEEtRSHEAQLQEmrqk 353

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   221 ---ELESLNARIKELEAIESRLEKTEITLKDDLTKLKTltvmlvdERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTtvte 297
Cdd:pfam01576  354 htqALEELTEQLEQAKRNKANLEKAKQALESENAELQA-------ELRTLQQAKQDSEHKRKKLEGQLQELQARLS---- 422

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   298 klieETKRAlksKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLN--------- 368
Cdd:pfam01576  423 ----ESERQ---RAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNlstrlrqle 495

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   369 QDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKA--QFLSQELEHAKMELAK 446
Cdd:pfam01576  496 DERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALtqQLEEKAAAYDKLEKTK 575


                   ....*...
gi 295424124   447 YKLAEKTE 454
Cdd:pfam01576  576 NRLQQELD 583

SCP-1

pfam05483

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...

6-531

3.44e-08

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.

Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 57.42 E-value: 3.44e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    6 QQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKiMAKLTNEDSQNRQLRQ 85
Cdd:pfam05483 228 EEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEK-KDHLTKELEDIKMSLQ 306

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   86 KLAALSRQIDE-LEETNRSLRKAEEELQDIKDKINKGEYGNSGImdeVDELRKRVLDMEgkdeELIKMEEQcrdlnkRLE 164
Cdd:pfam05483 307 RSMSTQKALEEdLQIATKTICQLTEEKEAQMEELNKAKAAHSFV---VTEFEATTCSLE----ELLRTEQQ------RLE 373

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  165 KETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEI 244
Cdd:pfam05483 374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIH 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  245 TLKDDLTKLKTLT---VMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETK--------------RAL 307
Cdd:pfam05483 454 DLEIQLTAIKTSEehyLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKkhqediinckkqeeRML 533

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  308 KSKTDAEEK-------MYSVTKE----RDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQdsSKSTA 376
Cdd:pfam05483 534 KQIENLEEKemnlrdeLESVREEfiqkGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENK--NKNIE 611

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  377 ALHQENNKIKELSQeVENLKLKLKDMKA--IEDDLMKTEDEYETLERRYANERDKAQfLSQELEHAKMELAKYKLAEKTe 454
Cdd:pfam05483 612 ELHQENKALKKKGS-AENKQLNAYEIKVnkLELELASAKQKFEEIIDNYQKEIEDKK-ISEEKLLEEVEKAKAIADEAV- 688

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295424124  455 ssheqwlfrRLQEE-EAKSGHLSREVDALKEK-IHEYmatEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKEL 531
Cdd:pfam05483 689 ---------KLQKEiDKRCQHKIAEMVALMEKhKHQY---DKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAEL 755

Mplasa_alph_rch

TIGR04523

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...

45-452

4.06e-08

Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 56.95 E-value: 4.06e-08

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   45 EQKATRLEKELQTQTTEFHQNQDKI----------MAKLTNEDSQNRQLRQKLAALSRQI----DELEETNRSLRKAEEE 110
Cdd:TIGR04523  32 DTEEKQLEKKLKTIKNELKNKEKELknldknlnkdEEKINNSNNKIKILEQQIKDLNDKLkknkDKINKLNSDLSKINSE 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  111 LQDIKDKINKGEygnsgimDEVDELRKrvldmegkdeELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKL 190
Cdd:TIGR04523 112 IKNDKEQKNKLE-------VELNKLEK----------QKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENE 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  191 EDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEK 270
Cdd:TIGR04523 175 LNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ 254

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  271 LKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAE---------------EKMYSVTKERDDLRNKLKAEE 335
Cdd:TIGR04523 255 LNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnqkeqdwnkelkSELKNQEKKLEEIQNQISQNN 334

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  336 EKGHDLLSKVTILKNRLQSLEAiekdfVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDM-----------KA 404
Cdd:TIGR04523 335 KIISQLNEQISQLKKELTNSES-----ENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLeskiqnqeklnQQ 409

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*...
gi 295424124  405 IEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEK 452
Cdd:TIGR04523 410 KDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIK 457

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

85-548

6.05e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 56.31 E-value: 6.05e-08

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  85 QKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEygnsgimDEVDELRKRVLDMEgKDEELIKMEEQCRDLNKRLE 164
Cdd:COG4717   71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELE-------AELEELREELEKLE-KLLQLLPLYQELEALEAELA 142

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 165 KETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNL-EKEKMTTKQLSEELESLNARIKELEAIESRLEKTE 243
Cdd:COG4717  143 ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQRLAELEEELEEAQEEL 222

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 244 ITLKDDLTKLKTLTvmlvdERKTMSEKLKQTEDKLQSTTSQL------QAEQNKVTTVTEKLIEETKRALKSKTDAEEKM 317
Cdd:COG4717  223 EELEEELEQLENEL-----EAAALEERLKEARLLLLIAAALLallglgGSLLSLILTIAGVLFLVLGLLALLFLLLAREK 297

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 318 YSVTKERDDLRNKLKAEEEKGHDLLSkvtiLKNRLQSLEAIEKDFVKNKLNQdssksTAALHQENNKIKELSQEVENLKL 397
Cdd:COG4717  298 ASLGKEAEELQALPALEELEEEELEE----LLAALGLPPDLSPEELLELLDR-----IEELQELLREAEELEEELQLEEL 368

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 398 KLKDMKAIEDDLMKTEDEYE---TLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQW--LFRRLQEEEAKS 472
Cdd:COG4717  369 EQEIAALLAEAGVEDEEELRaalEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELeeLEEELEELEEEL 448

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 295424124 473 GHLSREVDALKEKIHEyMATEDLICHLQGDHSLLQKKLNQQENRNR--DLGREIenLTKELERYRhfsKSLRPSLNER 548
Cdd:COG4717  449 EELREELAELEAELEQ-LEEDGELAELLQELEELKAELRELAEEWAalKLALEL--LEEAREEYR---EERLPPVLER 520

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

34-306

1.03e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.16 E-value: 1.03e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  34 LALAEARAQEEEQKAtrLEKELQtqttEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEetnRSLRKAEEELQD 113
Cdd:COG4942   10 LLALAAAAQADAAAE--AEAELE----QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALA---RRIRALEQELAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 114 IKDKINKGEygnsgimDEVDELRKRvldmegkdeelikMEEQCRDLNKRLEKETVQSKDFKLEVdklsvritaLEKLEDA 193
Cdd:COG4942   81 LEAELAELE-------KEIAELRAE-------------LEAQKEELAELLRALYRLGRQPPLAL---------LLSPEDF 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 194 LDKSKqecyslkcNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVML---VDERKTMSEK 270
Cdd:COG4942  132 LDAVR--------RLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALealKAERQKLLAR 203

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 295424124 271 LKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRA 306
Cdd:COG4942  204 LEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

207-445

1.54e-07

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 55.41 E-value: 1.54e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 207 NLEKEKMTTKQLSEELEslnariKELEAIESRLEKTEITLKDdlTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQ 286
Cdd:COG3206  165 NLELRREEARKALEFLE------EQLPELRKELEEAEAALEE--FRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELA 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 287 AEQNKVTTVTEKLieETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAiekdfvknK 366
Cdd:COG3206  237 EAEARLAALRAQL--GSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRA--------Q 306

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295424124 367 LNQDSSKSTAALHQEnnkIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELA 445
Cdd:COG3206  307 LQQEAQRILASLEAE---LEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEA 382

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

209-549

1.65e-07

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.45 E-value: 1.65e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   209 EKEKMTTKQL---SEELESLNARIKELEA----IESRLEKTE--ITLKDDLTKL-KTLTVMLVDERKtmsEKLKQTEDKL 278
Cdd:TIGR02168  172 ERRKETERKLertRENLDRLEDILNELERqlksLERQAEKAEryKELKAELRELeLALLVLRLEELR---EELEELQEEL 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   279 QSTTSQLQAEQNKVTTVTEKLieETKRALKSKtdAEEKMYSVTKERDDLRNKLkaeeekgHDLLSKVTILKNRLQSLEai 358
Cdd:TIGR02168  249 KEAEEELEELTAELQELEEKL--EELRLEVSE--LEEEIEELQKELYALANEI-------SRLEQQKQILRERLANLE-- 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   359 ekdfvknklnQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLmktEDEYETLERRYANERDKAQFLSQELE 438
Cdd:TIGR02168  316 ----------RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESL---EAELEELEAELEELESRLEELEEQLE 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   439 HAKMELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEKIHEYMATEdlichLQGDHSLLQKKLNQQENRNR 518
Cdd:TIGR02168  383 TLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE-----LQAELEELEEELEELQEELE 457

                          330       340       350
                   ....*....|....*....|....*....|.
gi 295424124   519 DLGREIENLTKELERYRHFSKSLRPSLNERR 549
Cdd:TIGR02168  458 RLEEALEELREELEEAEQALDAAERELAQLQ 488

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

108-533

2.04e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.77 E-value: 2.04e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 108 EEELQDIKDKINKGEYGNSGI-MDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEketvqskDFKLEVDKLSVRITA 186
Cdd:COG4717   48 LERLEKEADELFKPQGRKPELnLKELKELEEELKEAEEKEEEYAELQEELEELEEELE-------ELEAELEELREELEK 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 187 LEKLEDALDKSKQecyslkcnLEKEKMTTKQLSEELESLNARIKELEAIESRLEKteitLKDDLTKLKTltvmlvDERKT 266
Cdd:COG4717  121 LEKLLQLLPLYQE--------LEALEAELAELPERLEELEERLEELRELEEELEE----LEAELAELQE------ELEEL 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 267 MSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLieETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEE---------- 336
Cdd:COG4717  183 LEQLSLATEEELQDLAEELEELQQRLAELEEEL--EEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaalla 260

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 337 ---KGHDLLSKVTILKNRLQSLEAI------EKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIED 407
Cdd:COG4717  261 llgLGGSLLSLILTIAGVLFLVLGLlallflLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELL 340

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 408 DLMKTEDEYETLERRYANERDKAQFlsQELEHAKMELAKYKLAEkTESSHEQWL--FRRLQEEEAKSGHLSREVDALKEK 485
Cdd:COG4717  341 ELLDRIEELQELLREAEELEEELQL--EELEQEIAALLAEAGVE-DEEELRAALeqAEEYQELKEELEELEEQLEELLGE 417

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*...
gi 295424124 486 IHEYMATEDLichlqgdhSLLQKKLNQQENRNRDLGREIENLTKELER 533
Cdd:COG4717  418 LEELLEALDE--------EELEEELEELEEELEELEEELEELREELAE 457

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

4-243

2.29e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.00 E-value: 2.29e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   4 DEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQL 83
Cdd:COG4942   20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  84 RQKLAALSRQIDELEETNRS-----LRKAEEELQDIKDKINKGEYgnsgimdeVDELRKRVLDMEGKDEELikmeeqcRD 158
Cdd:COG4942  100 EAQKEELAELLRALYRLGRQpplalLLSPEDFLDAVRRLQYLKYL--------APARREQAEELRADLAEL-------AA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 159 LNKRLEKETvqskdfklevDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKmttKQLSEELESLNARIKELEAIESR 238
Cdd:COG4942  165 LRAELEAER----------AELEALLAELEEERAALEALKAERQKLLARLEKEL---AELAAELAELQQEAEELEALIAR 231


                 ....*
gi 295424124 239 LEKTE 243
Cdd:COG4942  232 LEAEA 236

SMC_prok_B

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...

176-488

2.60e-07

Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 54.68 E-value: 2.60e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   176 EVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEkmtTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKT 255
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEE---LEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   256 LTVMLVDERKTMSEKLKQTEDKLQsttsQLQAEQNKVTTVTEKLIEETKrALKSKTDAEEKMYSVTKER-DDLRNKLKAE 334
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELA----EAEAEIEELEAQIEQLKEELK-ALREALDELRAELTLLNEEaANLRERLESL 829

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   335 EEKGHDllsKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQEnnKIKELSQEVENLKLKLKDMKAIEDDLMKTED 414
Cdd:TIGR02168  830 ERRIAA---TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELES--ELEALLNERASLEEALALLRSELEELSEELR 904

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   415 EYET----LERRYANERDKAQFLSQELEHAKMELA--KYKLAEKTESSHEQwLFRRLQEEEAKSGHLSREVDALKEKIHE 488
Cdd:TIGR02168  905 ELESkrseLRRELEELREKLAQLELRLEGLEVRIDnlQERLSEEYSLTLEE-AEALENKIEDDEEEARRRLKRLENKIKE 983

SMC_N

pfam02463

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

4-327

2.72e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 54.59 E-value: 2.72e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     4 DEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQL 83
Cdd:pfam02463  680 ELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKK 759

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    84 RQKLA----ALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDL 159
Cdd:pfam02463  760 EEKEEekseLSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELA 839

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   160 NKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRL 239
Cdd:pfam02463  840 LELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEI 919

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   240 EKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYS 319
Cdd:pfam02463  920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKER 999


                   ....*...
gi 295424124   320 VTKERDDL 327
Cdd:pfam02463 1000 LEEEKKKL 1007

PRK01156

chromosome segregation protein; Provisional

175-575

2.73e-07

chromosome segregation protein; Provisional

Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 54.52 E-value: 2.73e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 175 LEVDKLSvriTALEKLEDALDKSKQECYSLkcNLEKEKMTTKQLseELESLNARIKELEAIESRLEKTEITLKDDLTKLK 254
Cdd:PRK01156 159 LEINSLE---RNYDKLKDVIDMLRAEISNI--DYLEEKLKSSNL--ELENIKKQIADDEKSHSITLKEIERLSIEYNNAM 231

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 255 TLTVMLVDERKTMS---EKLKQTEDKLQSTTSQLQAEQNKVTTVTEkLIEETKRALKSKtdaeekmysVTKERDDLRNKL 331
Cdd:PRK01156 232 DDYNNLKSALNELSsleDMKNRYESEIKTAESDLSMELEKNNYYKE-LEERHMKIINDP---------VYKNRNYINDYF 301

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 332 KAEEekghDLLSKVTILKNRLQSLEAIEkdfvknklnqDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMK 411
Cdd:PRK01156 302 KYKN----DIENKKQILSNIDAEINKYH----------AIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNS 367

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 412 TEDEYETLERRYANERDKAQFLSQELEHAkmeLAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEK---IHE 488
Cdd:PRK01156 368 YLKSIESLKKKIEEYSKNIERMSAFISEI---LKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENldeLSR 444

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 489 YMA-------------------TEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELER-----------YRHFS 538
Cdd:PRK01156 445 NMEmlngqsvcpvcgttlgeekSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYleseeinksinEYNKI 524

                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 295424124 539 KSLRPSLNERRISDPQVFSKEVQTEAADSEppdYKSL 575
Cdd:PRK01156 525 ESARADLEDIKIKINELKDKHDKYEEIKNR---YKSL 558

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

2-469

3.03e-07

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 54.67 E-value: 3.03e-07

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     2 VVDEQQRLTAQLALQRQKIQALTTSAKEtqgkLALAEARAQEEEQKATrlEKELQTQTTEFhqnqdkimakltneDSQNR 81
Cdd:TIGR00606  459 VIKELQQLEGSSDRILELDQELRKAERE----LSKAEKNSLTETLKKE--VKSLQNEKADL--------------DRKLR 518

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    82 QLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNK 161
Cdd:TIGR00606  519 KLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNK 598

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   162 RLEKETVQSKDFKLEVDKLSVRITALE-KLEDALDKSKQECY--SLKCNLEKEKMTTKQLSEELESLNARIKELEAIES- 237
Cdd:TIGR00606  599 ELASLEQNKNHINNELESKEEQLSSYEdKLFDVCGSQDEESDleRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQs 678

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   238 ------RLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVtEKLIEETKRALKSKT 311
Cdd:TIGR00606  679 ccpvcqRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLK-EKEIPELRNKLQKVN 757

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   312 DAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKE---- 387
Cdd:TIGR00606  758 RDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEkqhe 837

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   388 ---LSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAK----YKLAEKTESSHEQW 460
Cdd:TIGR00606  838 ldtVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSlireIKDAKEQDSPLETF 917


                   ....*....
gi 295424124   461 LFRRLQEEE 469
Cdd:TIGR00606  918 LEKDQQEKE 926

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

33-242

5.61e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 53.77 E-value: 5.61e-07

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   33 KLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMA-----KLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKA 107
Cdd:COG4913   611 KLAALEAELAELEEELAEAEERLEALEAELDALQERREAlqrlaEYSWDEIDVASAEREIAELEAELERLDASSDDLAAL 690

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  108 EEELQDIKDKINKGEygnsgimDEVDELRKRvldMEGKDEELIKMEEQCRDLNKRLEKETvqskdfklEVDKLSVRITAL 187
Cdd:COG4913   691 EEQLEELEAELEELE-------EELDELKGE---IGRLEKELEQAEEELDELQDRLEAAE--------DLARLELRALLE 752

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 295424124  188 EKLEDALDKskqecyslkcnlEKEKMTTKQLSEELESLNARIKELeaiESRLEKT 242
Cdd:COG4913   753 ERFAAALGD------------AVERELRENLEERIDALRARLNRA---EEELERA 792

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

216-432

6.16e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.46 E-value: 6.16e-07

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 216 KQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTV 295
Cdd:COG4942   23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 296 TEKLIEETKRALK--------------SKTDAEEKMY---SVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAi 358
Cdd:COG4942  103 KEELAELLRALYRlgrqpplalllspeDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAELEAERAELEALLA- 181

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295424124 359 EKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQF 432
Cdd:COG4942  182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALKGKL 255

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

16-331

1.66e-06

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 52.10 E-value: 1.66e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    16 QRQKIQALTtSAKETQGKLALAEAR---AQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSR 92
Cdd:pfam01576  762 RKQRAQAVA-AKKKLELDLKELEAQidaANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEA 840

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    93 QIDELEE----TNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEgkdEELIKMEEQCRDLNKRLEKETV 168
Cdd:pfam01576  841 ELLQLQEdlaaSERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLE---EELEEEQSNTELLNDRLRKSTL 917

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   169 QSKDFKLEvdkLSVRITALEKLEDALDKSKQECYSLKCNLE--------KEKMTTKQLSEEL----ESLNARIKELEAIE 236
Cdd:pfam01576  918 QVEQLTTE---LAAERSTSQKSESARQQLERQNKELKAKLQemegtvksKFKSSIAALEAKIaqleEQLEQESRERQAAN 994

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   237 SRLEKTEITLKDdltklktlTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEK 316
Cdd:pfam01576  995 KLVRRTEKKLKE--------VLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATES 1066

                          330
                   ....*....|....*
gi 295424124   317 MYSVTKERDDLRNKL 331
Cdd:pfam01576 1067 NESMNREVSTLKSKL 1081

MAD

pfam05557

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...

39-545

2.48e-06

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.

Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 51.28 E-value: 2.48e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   39 ARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKI 118
Cdd:pfam05557  48 DRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELEL 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  119 NKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKR---LEKETVQSKDFKLEVDKLSVRITALEKLEDALD 195
Cdd:pfam05557 128 QSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAEAEQRikeLEFEIQSQEQDSEIVKNSKSELARIPELEKELE 207

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  196 KSKQECYSLKCNLEKEKMttkqLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMseklkQTE 275
Cdd:pfam05557 208 RLREHNKHLNENIENKLL----LKEEVEDLKRKLEREEKYREEAATLELEKEKLEQELQSWVKLAQDTGLNL-----RSP 278

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  276 DKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSL 355
Cdd:pfam05557 279 EDLSRRIEQLQQREIVLKEENSSLTSSARQLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGY 358

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  356 EAIEKDFVKNKLNQDSSKstaalhQENNKIKELSQEVENLKLKLKDMKAieddlmktedEYETLERRYANERDKAQFLSQ 435
Cdd:pfam05557 359 RAILESYDKELTMSNYSP------QLLERIEEAEDMTQKMQAHNEEMEA----------QLSVAEEELGGYKQQAQTLER 422

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  436 ELEhakmelakyklaektessheqwlFRRLQEEEAKSGHLSREVDALKEKIHEYMAT-----------EDLICH--LQGD 502
Cdd:pfam05557 423 ELQ-----------------------ALRQQESLADPSYSKEEVDSLRRKLETLELErqrlreqknelEMELERrcLQGD 479

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 295424124  503 HSL-----LQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSL 545
Cdd:pfam05557 480 YDPkktkvLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDL 527

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

231-527

4.32e-06

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 50.84 E-value: 4.32e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   231 ELEAIESRLEKTEITLKDDLTKLKTLTvmlvDERKTmSEKLKQTEDKLQSTTSQLQAEQnkvttvTEKLIEETKRALKSK 310
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLR----REREK-AERYQALLKEKREYEGYELLKE------KEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   311 TDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVtilkNRLQSLEAIEkdfVKNKLnqdsSKSTAALHQENNKIKELSQ 390
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKI----KDLGEEEQLR---VKEKI----GELEAEIASLERSIAEKER 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   391 EVENLKLKLKDmkaIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKyklaektessheqwLFRRLQEEEA 470
Cdd:TIGR02169  316 ELEDAEERLAK---LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELED--------------LRAELEEVDK 378

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 295424124   471 KSGHLSREVDALKEKIHEYmatEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENL 527
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKL---KREINELKRELDRLQEELQRLSEELADLNAAIAGI 432

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

12-483

5.11e-06

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 50.43 E-value: 5.11e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    12 QLALQRQKIQALTTSA--KETQGKLALAEARAQEEEQKATRLEKELQTQTTefhqnqdkimaKLTNEDSQNRQLRQKLAA 89
Cdd:TIGR00606  397 TLVIERQEDEAKTAAQlcADLQSKERLKQEQADEIRDEKKGLGRTIELKKE-----------ILEKKQEELKFVIKELQQ 465

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    90 LSRQIDELEETNRSLRKAEEEL------QDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEE---LIKME------- 153
Cdd:TIGR00606  466 LEGSSDRILELDQELRKAERELskaeknSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtttRTQMEmltkdkm 545

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   154 ---EQCRDLNKRLEKE-TVQSKDF---KLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLN 226
Cdd:TIGR00606  546 dkdEQIRKIKSRHSDElTSLLGYFpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYE 625

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   227 ARIKEL---EAIESRLEKteitLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNkvttvTEKLIEET 303
Cdd:TIGR00606  626 DKLFDVcgsQDEESDLER----LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQ-----TEAELQEF 696

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   304 KRALKSKTdaeekmYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVK--NKLNQDSSKSTAALHQE 381
Cdd:TIGR00606  697 ISDLQSKL------RLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNklQKVNRDIQRLKNDIEEQ 770

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   382 NNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDeyetLERRYANERDKAQFLSQELEHAKMELAKYKLAEK--TESSHEQ 459
Cdd:TIGR00606  771 ETLLGTIMPEEESAKVCLTDVTIMERFQMELKD----VERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHEldTVVSKIE 846

                          490       500
                   ....*....|....*....|....
gi 295424124   460 WLFRRLQEEEAKSGHLSREVDALK 483
Cdd:TIGR00606  847 LNRKLIQDQQEQIQHLKSKTNELK 870

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

4-527

6.16e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 50.35 E-value: 6.16e-06

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     4 DEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKaTRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQL 83
Cdd:TIGR00618  362 EVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDIL-QREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYA 440

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    84 RQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELikmEEQCRDLNKRL 163
Cdd:TIGR00618  441 ELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPL---CGSCIHPNPAR 517

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   164 eketVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTE 243
Cdd:TIGR00618  518 ----QDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNIT 593

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   244 ITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQN---KVTTVTEKLI-----EETKRALKSKTDAEE 315
Cdd:TIGR00618  594 VRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQElalKLTALHALQLtltqeRVREHALSIRVLPKE 673

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   316 KMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFvkNKLNQDSSKSTAALHQENNKIKELSQEVENL 395
Cdd:TIGR00618  674 LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREF--NEIENASSSLGSDLAAREDALNQSLKELMHQ 751

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   396 K------LKLKDMKAIEDDLM--KTEDEYETLERRYANERDKAQFLSQELehakmelakyklaEKTESSHEQWLFRRLQE 467
Cdd:TIGR00618  752 ArtvlkaRTEAHFNNNEEVTAalQTGAELSHLAAEIQFFNRLREEDTHLL-------------KTLEAEIGQEIPSDEDI 818

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   468 EEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENL 527
Cdd:TIGR00618  819 LNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKL 878

EzrA

pfam06160

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ...

42-547

7.17e-06

Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.

Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 49.47 E-value: 7.17e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   42 QEEEQKATRLEKELQTQTT--EFHQNQDKIMAKltnedsqnrqlrqKLAALSRQIDELEETNRSLR--KAEEELQDIKDK 117
Cdd:pfam06160  28 QEELSKVKKLNLTGETQEKfeEWRKKWDDIVTK-------------SLPDIEELLFEAEELNDKYRfkKAKKALDEIEEL 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  118 INKGEygnsgimDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLeKETVQSKDFKLEvdklsvriTALEKLEDALDK- 196
Cdd:pfam06160  95 LDDIE-------EDIKQILEELDELLESEEKNREEVEELKDKYREL-RKTLLANRFSYG--------PAIDELEKQLAEi 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  197 ----SKQECYSLKCNLEKEKMTTKQLSEELESLNARIkelEAIESRLEKTEITLKDDLTKLK-TLTVMLVD----ERKTM 267
Cdd:pfam06160 159 eeefSQFEELTESGDYLEAREVLEKLEEETDALEELM---EDIPPLYEELKTELPDQLEELKeGYREMEEEgyalEHLNV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  268 SEKLKQTEDKLQSTTSQLqaEQNKVTTVtEKLIEETKRALKSKTDAEEKMY----SVTKERDDLRNKLKAEEEKGHDLLS 343
Cdd:pfam06160 236 DKEIQQLEEQLEENLALL--ENLELDEA-EEALEEIEERIDQLYDLLEKEVdakkYVEKNLPEIEDYLEHAEEQNKELKE 312

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  344 KVTILK-------NRLQSLEAIEKDFvkNKLNQDSSKSTAALHqenNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEY 416
Cdd:pfam06160 313 ELERVQqsytlneNELERVRGLEKQL--EELEKRYDEIVERLE---EKEVAYSELQEELEEILEQLEEIEEEQEEFKESL 387

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  417 ETLERRYANERDKAQFLSQELEHAKMELAKYKL--------AEKTESSHE-QWLFRRLQEEEAKSGHLSREVDALKEKIH 487
Cdd:pfam06160 388 QSLRKDELEAREKLDEFKLELREIKRLVEKSNLpglpesylDYFFDVSDEiEDLADELNEVPLNMDEVNRLLDEAQDDVD 467

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 295424124  488 E-YMATEDLIchlqgDHSLLQKKLNQQENRnrdlgreienltkelerYRHFSKSLRPSLNE 547
Cdd:pfam06160 468 TlYEKTEELI-----DNATLAEQLIQYANR-----------------YRSSNPEVAEALTE 506

PTZ00121

MAEBL; Provisional

5-413

9.22e-06

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 9.22e-06

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    5 EQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEK-------ELQTQTTEFHQNQDKIMAKLTNED 77
Cdd:PTZ00121 1493 EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKaeekkkaDELKKAEELKKAEEKKKAEEAKKA 1572

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   78 SQNRQLRQKLAALSRQIDElEETNRSLRKAEEELQDIKDKINKGEYGNSGI--MDEVDELRKRVLDMEGKDEELIKMEEQ 155
Cdd:PTZ00121 1573 EEDKNMALRKAEEAKKAEE-ARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAeeLKKAEEEKKKVEQLKKKEAEEKKKAEE 1651

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  156 CR-----------DLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQecysLKCNLEKEKMTTKQLSEELES 224
Cdd:PTZ00121 1652 LKkaeeenkikaaEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEE----LKKKEAEEKKKAEELKKAEEE 1727

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  225 LNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQsttSQLQAEQNKVTTVTEKLIEETK 304
Cdd:PTZ00121 1728 NKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE---EELDEEDEKRRMEVDKKIKDIF 1804

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  305 ralksktDAEEKMYSVTKERDDLRNKLKAEEEKGhdlLSKVTILKN--RLQSLEAIEKDFVKNKLNQDSSKSTAALHQEN 382
Cdd:PTZ00121 1805 -------DNFANIIEGGKEGNLVINDSKEMEDSA---IKEVADSKNmqLEEADAFEKHKFNKNNENGEDGNKEADFNKEK 1874

                         410       420       430
                  ....*....|....*....|....*....|.
gi 295424124  383 NKIKELSQEVEnlklKLKDMKAIEDDLMKTE 413
Cdd:PTZ00121 1875 DLKEDDEEEIE----EADEIEKIDKDDIERE 1901

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

84-337

1.04e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 1.04e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   84 RQKLAALSRQIDELEETnrsLRKAEEELQDIKDkinkgeygnsgIMDEVDELRKRVLDMEGKDEELIKMEEQCRdlnkrl 163
Cdd:COG4913   609 RAKLAALEAELAELEEE---LAEAEERLEALEA-----------ELDALQERREALQRLAEYSWDEIDVASAER------ 668

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  164 eketvqskdfklevdklsvRITALEKLEDALDKSkqecyslkcnlekekmttkqlSEELESLNARIKELEAIESRLEKTE 243
Cdd:COG4913   669 -------------------EIAELEAELERLDAS---------------------SDDLAALEEQLEELEAELEELEEEL 708

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  244 ITLKDDLTKLKtltvmlvderktmsEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKE 323
Cdd:COG4913   709 DELKGEIGRLE--------------KELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEER 774

                         250
                  ....*....|....
gi 295424124  324 RDDLRNKLKAEEEK 337
Cdd:COG4913   775 IDALRARLNRAEEE 788

SMC_N

pfam02463

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

186-542

1.18e-05

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 49.20 E-value: 1.18e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   186 ALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKEleaiesRLEKTEITLKDDLTKLKtltvmlvDERK 265
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKL------ELEEEYLLYLDYLKLNE-------ERID 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   266 TMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETkralKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKV 345
Cdd:pfam02463  241 LLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEE----KEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   346 TILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKE---------LSQEVENLKLKLKDMKAIEDDLMKTEDEY 416
Cdd:pfam02463  317 KESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEeeleklqekLEQLEEELLAKKKLESERLSSAAKLKEEE 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   417 ETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRR--------LQEEEAKSGHLSREVDALKEKIHE 488
Cdd:pfam02463  397 LELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGklteekeeLEKQELKLLKDELELKKSEDLLKE 476

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....
gi 295424124   489 YMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLR 542
Cdd:pfam02463  477 TQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGR 530

PHA02562

endonuclease subunit; Provisional

51-272

1.31e-05

endonuclease subunit; Provisional

Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 48.86 E-value: 1.31e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  51 LEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQD-IKDKINKGEYGNSGIM 129
Cdd:PHA02562 179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDeLLNLVMDIEDPSAALN 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 130 DEVDELRKRVLDMEGKDEElIKMEE----------QCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQ 199
Cdd:PHA02562 259 KLNTAAAKIKSKIEQFQKV-IKMYEkggvcptctqQISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQSK 337

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424124 200 ECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAiESRLEKTEI-TLKDDLTKL---KTLTVMLVDERKTMSEKLK 272
Cdd:PHA02562 338 KLLELKNKISTNKQSLITLVDKAKKVKAAIEELQA-EFVDNAEELaKLQDELDKIvktKSELVKEKYHRGIVTDLLK 413

DUF4407

pfam14362

Domain of unknown function (DUF4407); This family of proteins is found in bacteria. Proteins ...

52-193

2.10e-05

Domain of unknown function (DUF4407); This family of proteins is found in bacteria. Proteins in this family are typically between 366 and 597 amino acids in length. There is a single completely conserved residue R that may be functionally important.

Pssm-ID: 464151 [Multi-domain] Cd Length: 295 Bit Score: 47.25 E-value: 2.10e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   52 EKELQTQTTEFHQN-QDKIMAKLTNE-DSQNRQLRQKLAALSRQIDELE-ETNRSLRKAEEEL-QDIKDKINKGEYGNSG 127
Cdd:pfam14362 105 EKEIDRELLEIQQEeADAAKAQLAAAyRARLAELEAQIAALDAEIDAAEaRLDALQAEARCELdGTPGTGTGVPGDGPVA 184

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 295424124  128 --IMDEVDELRKRVLDMEGK-DEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDA 193
Cdd:pfam14362 185 ktKQAQLDAAQAELAALQAQnDARLAALRAELARLTAERAAARARSQAAIDGDDGLLARLEALNRLTTE 253

PRK11281

mechanosensitive channel MscK;

192-527

2.43e-05

mechanosensitive channel MscK;

Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 48.37 E-value: 2.43e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  192 DALDKSKQecyslkcNLEKEKMTTKQLSEELESLNAR---IKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMS 268
Cdd:PRK11281   46 DALNKQKL-------LEAEDKLVQQDLEQTLALLDKIdrqKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETL 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  269 EK--LKQTEDKLQSTTSQLQAEQNKVTTVTEKLIeetkrALKSKTD-AEEKMYSVTKERDDLRNKLKAEEEKGHDLL-SK 344
Cdd:PRK11281  119 STlsLRQLESRLAQTLDQLQNAQNDLAEYNSQLV-----SLQTQPErAQAALYANSQRLQQIRNLLKGGKVGGKALRpSQ 193

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  345 VTILKNRLQSLEAiekdfvKNKLNQDSSKSTAALhQE---------NNKIKELSQEVENLKLKLKDMKAIEDDlmKTEDE 415
Cdd:PRK11281  194 RVLLQAEQALLNA------QNDLQRKSLEGNTQL-QDllqkqrdylTARIQRLEHQLQLLQEAINSKRLTLSE--KTVQE 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  416 YETLERryANERDKAQFLSQELEHAKmELAKYkLAEKTESSHE---------QWLFRRLQEEEaksghlsrevdALKEKI 486
Cdd:PRK11281  265 AQSQDE--AARIQANPLVAQELEINL-QLSQR-LLKATEKLNTltqqnlrvkNWLDRLTQSER-----------NIKEQI 329

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 295424124  487 HEymatedlichLQGdhSL-LQKKLNQQENR------NRDLGREIENL 527
Cdd:PRK11281  330 SV----------LKG--SLlLSRILYQQQQAlpsadlIEGLADRIADL 365

PHA02562

endonuclease subunit; Provisional

159-411

2.91e-05

endonuclease subunit; Provisional

Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 47.70 E-value: 2.91e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 159 LNKRLEKE-TVQSKDFKLEVDKLSVRITALEKLEDALDK-SKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEaie 236
Cdd:PHA02562 171 LNKDKIRElNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKkNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLV--- 247

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 237 srleKTEITLKDDLTKLKTLTVMLVDERKTMS--EKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRaLKSKTDAE 314
Cdd:PHA02562 248 ----MDIEDPSAALNKLNTAAAKIKSKIEQFQkvIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHS-LEKLDTAI 322

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 315 EKMYSVTKERDDLRNKLkaeeekgHDLLSKVTILKNRLQSLEAIEKDFVK--NKLNQDSSKSTAALHQENNKIKELSQEV 392
Cdd:PHA02562 323 DELEEIMDEFNEQSKKL-------LELKNKISTNKQSLITLVDKAKKVKAaiEELQAEFVDNAEELAKLQDELDKIVKTK 395

                        250
                 ....*....|....*....
gi 295424124 393 ENLKLKlKDMKAIEDDLMK 411
Cdd:PHA02562 396 SELVKE-KYHRGIVTDLLK 413

YhaN

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

352-556

3.08e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];

Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.84 E-value: 3.08e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 352 LQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQ 431
Cdd:COG4717   40 LAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 432 FLSQELEHAKMELAKYKLAEKTESSHEQWlfRRLQEEEAKSGHLSREVDALKEKIHEY------------MATEDLICHL 499
Cdd:COG4717  120 KLEKLLQLLPLYQELEALEAELAELPERL--EELEERLEELRELEEELEELEAELAELqeeleelleqlsLATEEELQDL 197

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 295424124 500 QGDHSLLQKKLNQQENRNRDLGREIENLTKELERYrhfSKSLRPSLNERRISDPQVF 556
Cdd:COG4717  198 AEELEELQQRLAELEEELEEAQEELEELEEELEQL---ENELEAAALEERLKEARLL 251

SMC_N

pfam02463

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...

10-608

3.71e-05

Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 47.66 E-value: 3.71e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    10 TAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQnqdKIMAKLTNEDSQNRQLRQKLAA 89
Cdd:pfam02463  178 LIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYL---KLNEERIDLLQELLRDEQEEIE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    90 LSRQIDELEET--NRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQcrdlNKRLEKET 167
Cdd:pfam02463  255 SSKQEIEKEEEklAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKE----KKKAEKEL 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   168 VQSKDFKLEvdklsvritaLEKLEDALDKSKQECYSLKCNLEKEKmttkqlseelesLNARIKELEAIESRLEKTEITLK 247
Cdd:pfam02463  331 KKEKEEIEE----------LEKELKELEIKREAEEEEEEELEKLQ------------EKLEQLEEELLAKKKLESERLSS 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   248 DDLTKLKTLTVMLVDERKtmSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAE--------EKMYS 319
Cdd:pfam02463  389 AAKLKEEELELKSEEEKE--AQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELekqelkllKDELE 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   320 VTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKelsQEVENLKLKL 399
Cdd:pfam02463  467 LKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGD---LGVAVENYKV 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   400 KDMKAIEDDLMKTEDEYETLERRYANERDKAQF---LSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQE--EEAKSGH 474
Cdd:pfam02463  544 AISTAVIVEVSATADEVEERQKLVRALTELPLGarkLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEadEDDKRAK 623

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   475 LSREVDALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNERRISDPQ 554
Cdd:pfam02463  624 VVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKK 703

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 295424124   555 VFSKEVQTEAADSEPPDYKSLIPLERAVINGQFYEENEDQDDDPNEEESVLSFR 608
Cdd:pfam02463  704 KEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRL 757

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

291-533

3.96e-05

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 47.76 E-value: 3.96e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   291 KVTTVTEKLIEETKRALKSKTDAEEkmysvtkeRDDLRNKLkaEEEKGHDLLSKVTILknrLQSLEAIEKDFvkNKLNQD 370
Cdd:TIGR02169  188 RLDLIIDEKRQQLERLRREREKAER--------YQALLKEK--REYEGYELLKEKEAL---ERQKEAIERQL--ASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   371 SSKSTAALHQENNKIKELSQEVENLKLKLKDMKaiEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLA 450
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLG--EEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAE 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   451 -EKTESSHEQwLFRRLQEEEAKSGHLSREVDALKEkihEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTK 529
Cdd:TIGR02169  331 iDKLLAEIEE-LEREIEEERKRRDKLTEEYAELKE---ELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKR 406


                   ....
gi 295424124   530 ELER 533
Cdd:TIGR02169  407 ELDR 410

PRK01156

chromosome segregation protein; Provisional

90-547

4.18e-05

chromosome segregation protein; Provisional

Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 47.59 E-value: 4.18e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  90 LSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETVQ 169
Cdd:PRK01156 192 LKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEK 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 170 SKDFKlEVDKLSVRITaleklEDALDKSKQEC---YSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITL 246
Cdd:PRK01156 272 NNYYK-ELEERHMKII-----NDPVYKNRNYIndyFKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKK 345

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 247 KDdltklktltvmlVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDD 326
Cdd:PRK01156 346 SR------------YDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNE 413

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 327 LRNKLKAEEEKGHDLLSKVTILKNRLQSLE-------------AIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVE 393
Cdd:PRK01156 414 INVKLQDISSKVSSLNQRIRALRENLDELSrnmemlngqsvcpVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVK 493

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 394 NLKLKLKDMKAIEDDLMKTEdeyetlERRYANERDKAQFLSQELEHAKMELAKYKLAEktessheqwlfrrLQEEEAKSG 473
Cdd:PRK01156 494 DIDEKIVDLKKRKEYLESEE------INKSINEYNKIESARADLEDIKIKINELKDKH-------------DKYEEIKNR 554

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 474 HLSREVDALKEKIHEY---MATEDLIC--HLQGDHSLLQKKLNQQENRNRDLGREIENLT----KELERYRHFSKSLRPS 544
Cdd:PRK01156 555 YKSLKLEDLDSKRTSWlnaLAVISLIDieTNRSRSNEIKKQLNDLESRLQEIEIGFPDDKsyidKSIREIENEANNLNNK 634


                 ...
gi 295424124 545 LNE 547
Cdd:PRK01156 635 YNE 637

PRK01156

chromosome segregation protein; Provisional

2-552

6.23e-05

chromosome segregation protein; Provisional

Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 46.82 E-value: 6.23e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   2 VVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFhQNQDKIMAKLTNEDSQNR 81
Cdd:PRK01156 174 VIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDY-NNLKSALNELSSLEDMKN 252

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  82 QLRQKLAALSRQIDELEETNRSLRKAEEELQDIkdkINKGEYGNSGIMDEVDELRKRVLD----MEGKDEELIKMEEQCR 157
Cdd:PRK01156 253 RYESEIKTAESDLSMELEKNNYYKELEERHMKI---INDPVYKNRNYINDYFKYKNDIENkkqiLSNIDAEINKYHAIIK 329

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 158 DLNKrLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEEL-ESLNARIKELEAIE 236
Cdd:PRK01156 330 KLSV-LQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFIsEILKIQEIDPDAIK 408

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 237 SRLEKTEITLKDDLTKLKTLTVMLvderktmsEKLKQTEDKLQSTTSQLQAeQNKVTTVTEKLIEETKRALKSktDAEEK 316
Cdd:PRK01156 409 KELNEINVKLQDISSKVSSLNQRI--------RALRENLDELSRNMEMLNG-QSVCPVCGTTLGEEKSNHIIN--HYNEK 477

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 317 MYSVTKERDDLRNKLKAEEEKGHDLLSkvtiLKNRLQSlEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLK 396
Cdd:PRK01156 478 KSRLEEKIREIEIEVKDIDEKIVDLKK----RKEYLES-EEINKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIK 552

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 397 LKLKDMKaIEDDLMKTEDEYETLERRYA----NERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEE---- 468
Cdd:PRK01156 553 NRYKSLK-LEDLDSKRTSWLNALAVISLidieTNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEannl 631

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 469 ---EAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYRHFSKSLRPSL 545
Cdd:PRK01156 632 nnkYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRI 711


                 ....*....
gi 295424124 546 NE--RRISD 552
Cdd:PRK01156 712 NElsDRIND 720

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

330-535

6.51e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.85 E-value: 6.51e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 330 KLKAEEEKgHDLLSKVTILKNRLQSLEAIEKDfvKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAiedDL 409
Cdd:COG1196  217 ELKEELKE-LEAELLLLKLRELEAELEELEAE--LEELEAELEELEAELAELEAELEELRLELEELELELEEAQA---EE 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 410 MKTEDEYETLERRYANERDKAQFLSQELEHAKMELA----KYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREVDALKEK 485
Cdd:COG1196  291 YELLAELARLEQDIARLEERRRELEERLEELEEELAeleeELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 295424124 486 IHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYR 535
Cdd:COG1196  371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE 420

COG5283

Phage-related tail protein [Mobilome: prophages, transposons];

7-163

7.07e-05

Phage-related tail protein [Mobilome: prophages, transposons];

Pssm-ID: 444094 [Multi-domain] Cd Length: 747 Bit Score: 46.77 E-value: 7.07e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   7 QRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMA---KLTNEDSQNRQL 83
Cdd:COG5283   10 KPFKSALESAKQRVAALAQALKALEAPTRALARALERAKQAAARLQTKYNKLRQSLQRLRQALDQagiDTRQLSAAQRRL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  84 RQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINK-GEYGNSGI-------------MDEVDELR--KRVLDMEGKDE 147
Cdd:COG5283   90 RSSLEQTNRQLERQQQRLARLGARQDRLKAARARLQRlAGAGAAAAaigaalaasvkpaIDFEDAMAdvAATVDLDKSSE 169

                        170
                 ....*....|....*.
gi 295424124 148 ELIKMEEQCRDLNKRL 163
Cdd:COG5283  170 QFKALGKQARELSAQT 185

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

77-291

7.43e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.98 E-value: 7.43e-05

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  77 DSQNRQLRQKLAALSRQIDELEETnrsLRKAEEELQDIKDKINKGEygnsgimDEVDELRKRvldMEGKDEELIKMEEQC 156
Cdd:COG3883   15 DPQIQAKQKELSELQAELEAAQAE---LDALQAELEELNEEYNELQ-------AELEALQAE---IDKLQAEIAEAEAEI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 157 RDLNKRLEKETVQSKDFKLEVDKLSV------------RITALEKLEDALDKSKQECYSLKCNLEKEKmttKQLSEELES 224
Cdd:COG3883   82 EERREELGERARALYRSGGSVSYLDVllgsesfsdfldRLSALSKIADADADLLEELKADKAELEAKK---AELEAKLAE 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424124 225 LNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNK 291
Cdd:COG3883  159 LEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225

CCDC158

pfam15921

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...

1-464

7.57e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.

Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 46.65 E-value: 7.57e-05

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     1 MVVDEQQRLTAQLALQRQKIQALTTSAK-ETQGKLALAEARAQ---EEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNE 76
Cdd:pfam15921  412 ITIDHLRRELDDRNMEVQRLEALLKAMKsECQGQMERQMAAIQgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTL 491

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    77 DSQNRQLRQKLAALSRQIDELEETNRSLRK----AEEELQDIKDKINKGEYGNSgIMDEVDELRkrvLDMEGKDEELIKM 152
Cdd:pfam15921  492 ESSERTVSDLTASLQEKERAIEATNAEITKlrsrVDLKLQELQHLKNEGDHLRN-VQTECEALK---LQMAEKDKVIEIL 567

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   153 EEQCRDLNK-----------------RLEKET----VQSKDFKLEVDKLSVRITALE----------------------- 188
Cdd:pfam15921  568 RQQIENMTQlvgqhgrtagamqvekaQLEKEIndrrLELQEFKILKDKKDAKIRELEarvsdlelekvklvnagserlra 647

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   189 ---------KLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIK-ELEAIESRLEKTEITLKD---------- 248
Cdd:pfam15921  648 vkdikqerdQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmQLKSAQSELEQTRNTLKSmegsdghamk 727

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   249 -DLTKLKTLT------------VMLVDERKTMSEK----LKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKT 311
Cdd:pfam15921  728 vAMGMQKQITakrgqidalqskIQFLEEAMTNANKekhfLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVA 807

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   312 DAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKL-----------NQDSSKSTAA-LH 379
Cdd:pfam15921  808 NMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQGPGYTSNSSMKPRLlqpasftrthsNVPSSQSTASfLS 887

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   380 QENNKIKELSQE-VENLKLKLKDMKAI-----EDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLaeKT 453
Cdd:pfam15921  888 HHSRKTNALKEDpTRDLKQLLQELRSVineepTVQLSKAEDKGRAPSLGALDDRVRDCIIESSLRSDICHSSSNSL--QT 965

                          570
                   ....*....|.
gi 295424124   454 ESSHEQWLFRR 464
Cdd:pfam15921  966 EGSKSSETCSR 976

MukB

COG3096

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...

4-309

9.79e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.48 E-value: 9.79e-05

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    4 DEQQRLTAQ--LALQ-RQKIQALttsaKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKimakLTNEDSQN 80
Cdd:COG3096   400 DYQQALDVQqtRAIQyQQAVQAL----EKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQK----LSVADAAR 471

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   81 RQLRQKLAALSRQIDELEeTNRSLRKAEEELQDIKDKINkgeygnsgIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLN 160
Cdd:COG3096   472 RQFEKAYELVCKIAGEVE-RSQAWQTARELLRRYRSQQA--------LAQRLQQLRAQLAELEQRLRQQQNAERLLEEFC 542

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  161 KRLEKEtVQSKDfklevdklsvritALEKLEDALDKSKQECYSLKCNLEKEKMTTKQlseELESLNARIKELEAIESRLe 240
Cdd:COG3096   543 QRIGQQ-LDAAE-------------ELEELLAELEAQLEELEEQAAEAVEQRSELRQ---QLEQLRARIKELAARAPAW- 604

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 295424124  241 kteITLKDDLTKLktltvmlvderktmSEKLKQTEDKLQSTTSQLQ--AEQNKVTTVTEKLIEETKRALKS 309
Cdd:COG3096   605 ---LAAQDALERL--------------REQSGEALADSQEVTAAMQqlLEREREATVERDELAARKQALES 658

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

4-189

1.03e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.06 E-value: 1.03e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    4 DEQQRLTAQLALQRQKIQALTTSAKETqgKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKImakltneDSQNRQL 83
Cdd:COG4913   262 ERYAAARERLAELEYLRAALRLWFAQR--RLELLEAELEELRAELARLEAELERLEARLDALREEL-------DELEAQI 332

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   84 RQ----KLAALSRQIDELEETnrsLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVldmegkDEELIKMEEQCRDL 159
Cdd:COG4913   333 RGnggdRLEQLEREIERLERE---LEERERRRARLEALLAALGLPLPASAEEFAALRAEA------AALLEALEEELEAL 403

                         170       180       190
                  ....*....|....*....|....*....|
gi 295424124  160 NKRLEKETVQSKDFKLEVDKLSVRITALEK 189
Cdd:COG4913   404 EEALAEAEAALRDLRRELRELEAEIASLER 433

SMC_prok_A

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...

3-233

1.04e-04

Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 46.21 E-value: 1.04e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124     3 VDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQD-------KIMAKLTN 75
Cdd:TIGR02169  793 IPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEnlngkkeELEEELEE 872

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    76 EDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQdikdkinkgeygnsgimDEVDELRKRVLDMEGKDEELIKMEEQ 155
Cdd:TIGR02169  873 LEAALRDLESRLGDLKKERDELEAQLRELERKIEELE-----------------AQIEKKRKRLSELKAKLEALEEELSE 935

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   156 CRDLNKRLE---KETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTtkqLSEELESLNARIKEL 232
Cdd:TIGR02169  936 IEDPKGEDEeipEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAK---LEEERKAILERIEEY 1012


                   .
gi 295424124   233 E 233
Cdd:TIGR02169 1013 E 1013

PRK01156

chromosome segregation protein; Provisional

54-406

1.26e-04

chromosome segregation protein; Provisional

Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 46.05 E-value: 1.26e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  54 ELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNR----SLRKAEEELQDIKDkinkgEYGN--SG 127
Cdd:PRK01156 406 AIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVcpvcGTTLGEEKSNHIIN-----HYNEkkSR 480

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 128 IMDEVDELRKRVLDMEGKDEELIKMEEQCRDLN-KRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKC 206
Cdd:PRK01156 481 LEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEiNKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKL 560

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 207 NLEKEKMTtkqlseELESLNARIK--ELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQ 284
Cdd:PRK01156 561 EDLDSKRT------SWLNALAVISliDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNK 634

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 285 LqaeqnkvttvteKLIEETKRA---LKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVtilknrlqsleaiEKD 361
Cdd:PRK01156 635 Y------------NEIQENKILiekLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKS-------------RKA 689

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 295424124 362 FVKNKLNQDSSKSTAALHQENNKikELSQEVENLKLKLKDMKAIE 406
Cdd:PRK01156 690 LDDAKANRARLESTIEILRTRIN--ELSDRINDINETLESMKKIK 732

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

21-471

1.48e-04

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 45.81 E-value: 1.48e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    21 QALTTSAKETQGKLALAEaRAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKL----AALSRQIDE 96
Cdd:TIGR00606  667 QFITQLTDENQSCCPVCQ-RVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLApgrqSIIDLKEKE 745

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    97 LEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEvDELRKRVLDMEGKDEELikmEEQCRDLNKRLEKETVQSKDFKLE 176
Cdd:TIGR00606  746 IPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPE-EESAKVCLTDVTIMERF---QMELKDVERKIAQQAAKLQGSDLD 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   177 VDKLSVRITALEKLEDaLDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTL 256
Cdd:TIGR00606  822 RTVQQVNQEKQEKQHE-LDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSL 900

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   257 TVMLVDERKTMSeKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKlkaeeE 336
Cdd:TIGR00606  901 IREIKDAKEQDS-PLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLK-----Q 974

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   337 KGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQEN-------NKIKELSQEVENLKLKLKDMKAIE--D 407
Cdd:TIGR00606  975 KETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNltlrkreNELKEVEEELKQHLKEMGQMQVLQmkQ 1054

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 295424124   408 DLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEEAK 471
Cdd:TIGR00606 1055 EHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKYREMMIVMRTTELVNK 1118

DR0291

COG1579

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

77-242

1.53e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.15 E-value: 1.53e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  77 DSQNRQLRQKLAALSRQIDELEET----NRSLRKAEEELQDIKDKINKGEygnsgimDEVDELRKRVLDMEGKDEELIKM 152
Cdd:COG1579   16 DSELDRLEHRLKELPAELAELEDElaalEARLEAAKTELEDLEKEIKRLE-------LEIEEVEARIKKYEEQLGNVRNN 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 153 EEQcRDLNKRLEKEtvqskdfKLEVDKLSVRI----TALEKLEDALDKSKQECYSLKCNLEKEKmttKQLSEELESLNAR 228
Cdd:COG1579   89 KEY-EALQKEIESL-------KRRISDLEDEIlelmERIEELEEELAELEAELAELEAELEEKK---AELDEELAELEAE 157

                        170
                 ....*....|....
gi 295424124 229 IKELEAIESRLEKT 242
Cdd:COG1579  158 LEELEAEREELAAK 171

235kDa-fam

TIGR01612

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...

68-460

1.55e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.

Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 45.81 E-value: 1.55e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    68 KIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEE-LQDIKDKINKGEY-----GNSGIMDEVDELRKRVLD 141
Cdd:TIGR01612  483 KDIDENSKQDNTVKLILMRMKDFKDIIDFMELYKPDEVPSKNIiGFDIDQNIKAKLYkeieaGLKESYELAKNWKKLIHE 562

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   142 ----MEGKDEELIKMEEQCRDL-NKRLE--KETVQSKDFKLEVDklsvritalEKLEDALDKSK--QECYSLKCNLEKE- 211
Cdd:TIGR01612  563 ikkeLEEENEDSIHLEKEIKDLfDKYLEidDEIIYINKLKLELK---------EKIKNISDKNEyiKKAIDLKKIIENNn 633

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   212 -------KMTTKQLSEELESLNariKELEAIESRLEKTeitLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQ 284
Cdd:TIGR01612  634 ayidelaKISPYQVPEHLKNKD---KIYSTIKSELSKI---YEDDIDALYNELSSIVKENAIDNTEDKAKLDDLKSKIDK 707

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   285 LQAEQNKVTTVTEKL----IEETKRALkSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNrlqslEAIEK 360
Cdd:TIGR01612  708 EYDKIQNMETATVELhlsnIENKKNEL-LDIIVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAK-----EKDEL 781

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   361 DFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKaqFLSQELEHa 440
Cdd:TIGR01612  782 NKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDK--FINFENNC- 858

                          410       420
                   ....*....|....*....|
gi 295424124   441 kmelakyklAEKTESSHEQW 460
Cdd:TIGR01612  859 ---------KEKIDSEHEQF 869

PspC_subgroup_1

NF033838

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...

40-459

1.97e-04

Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 45.00 E-value: 1.97e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  40 RAQEEEQK-ATRLEKELQTQTTEFHQNQDKimakltNEDSQNRQLRQKLAALSRQIdeLEETNRSLRKAEEEL-QDIKDK 117
Cdd:NF033838  51 SGNESQKEhAKEVESHLEKILSEIQKSLDK------RKHTQNVALNKKLSDIKTEY--LYELNVLKEKSEAELtSKTKKE 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 118 INKGeygNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRlEKETVQSKDFKLEVDKLSVRITalekledaldKS 197
Cdd:NF033838 123 LDAA---FEQFKKDTLEPGKKVAEATKKVEEAEKKAKDQKEEDRR-NYPTNTYKTLELEIAESDVEVK----------KA 188

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 198 KQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDL-TKLKTLTVMLVD--ERKTMSEKLKQ- 273
Cdd:NF033838 189 ELELVKEEAKEPRDEEKIKQAKAKVESKKAEATRLEKIKTDREKAEEEAKRRAdAKLKEAVEKNVAtsEQDKPKRRAKRg 268

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 274 ------TEDKlqsttSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKerddlrnklKAEEEKGHDLLSKVTI 347
Cdd:NF033838 269 vlgepaTPDK-----KENDAKSSDSSVGEETLPSPSLKPEKKVAEAEKKVEEAKK---------KAKDQKEEDRRNYPTN 334

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 348 LKNRLQsLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEyetlERRYANER 427
Cdd:NF033838 335 TYKTLE-LEIAESDVKVKEAELELVKEEAKEPRNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEEE----AKRKAAEE 409

                        410       420       430
                 ....*....|....*....|....*....|..
gi 295424124 428 DKAQFLSQELEHAKMELAKYKLAEKTESSHEQ 459
Cdd:NF033838 410 DKVKEKPAEQPQPAPAPQPEKPAPKPEKPAEQ 441

CCCAP

pfam15964

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in ...

4-299

2.05e-04

Centrosomal colon cancer autoantigen protein family; CCCAP is a family of proteins found in eukaryotes. CCCAP is also known as SDCCAG8, serologically defined colon cancer antigen 8. It is associated with the centrosome.

Pssm-ID: 435040 [Multi-domain] Cd Length: 703 Bit Score: 45.28 E-value: 2.05e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    4 DEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQ- 82
Cdd:pfam15964 325 EAQQRESSAYEQVKQAVQMTEEANFEKTKALIQCEQLKSELERQKERLEKELASQQEKRAQEKEALRKEMKKEREELGAt 404

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   83 ---LRQKLAALSRQIDELEETNRSLRKAEEELQ---------------DIKDKINKGEYGNSGIMDEVDELRKRVL-DME 143
Cdd:pfam15964 405 mlaLSQNVAQLEAQVEKVTREKNSLVSQLEEAQkqlasqemdvtkvcgEMRYQLNQTKMKKDEAEKEHREYRTKTGrQLE 484

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  144 GKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSvriTALEKLEDALDKSKQECYSLKCNLEKE-KMTTKQLSEEL 222
Cdd:pfam15964 485 IKDQEIEKLGLELSESKQRLEQAQQDAARAREECLKLT---ELLGESEHQLHLTRLEKESIQQSFSNEaKAQALQAQQRE 561

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424124  223 ESLNARIKELEAiesRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKL 299
Cdd:pfam15964 562 QELTQKMQQMEA---QHDKTVNEQYSLLTSQNTFIAKLKEECCTLAKKLEEITQKSRSEVEQLSQEKEYLQDRLEKL 635

PRK12704

phosphodiesterase; Provisional

29-187

2.14e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.77 E-value: 2.14e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  29 ETQGKLALAEARaQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAE 108
Cdd:PRK12704  52 EAIKKEALLEAK-EEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKE 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 109 EELQDIKDKINKGEYGNSGImdEVDELRKRVLDmegkdeeliKMEEQCRD----LNKRLEKETvqskdfKLEVDKLSVRI 184
Cdd:PRK12704 131 EELEELIEEQLQELERISGL--TAEEAKEILLE---------KVEEEARHeaavLIKEIEEEA------KEEADKKAKEI 193


                 ...
gi 295424124 185 TAL 187
Cdd:PRK12704 194 LAQ 196

CwlO1

COG3883

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...

35-254

2.99e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];

Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 44.05 E-value: 2.99e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  35 ALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKltneDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDI 114
Cdd:COG3883   12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEEL----NEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREE 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 115 KDKINKGEYGNSGIMDEVDELrkrvldMEGKDEElikmeeqcrDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDAL 194
Cdd:COG3883   88 LGERARALYRSGGSVSYLDVL------LGSESFS---------DFLDRLSALSKIADADADLLEELKADKAELEAKKAEL 152

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 195 DKSKQECYSLKcnlekekmttKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLK 254
Cdd:COG3883  153 EAKLAELEALK----------AELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELE 202

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

5-115

3.14e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 44.62 E-value: 3.14e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   5 EQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLtneDSQNRQLR 84
Cdd:COG3206  250 GSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASL---EAELEALQ 326

                         90       100       110
                 ....*....|....*....|....*....|.
gi 295424124  85 QKLAALSRQIDELEETNRSLRKAEEELQDIK 115
Cdd:COG3206  327 AREASLQAQLAQLEARLAELPELEAELRRLE 357

EnvC

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...

2-103

3.30e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.98 E-value: 3.30e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   2 VVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNR 81
Cdd:COG4942  144 LAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223

                         90       100
                 ....*....|....*....|..
gi 295424124  82 QLRQKLAALSRQIDELEETNRS 103
Cdd:COG4942  224 ELEALIARLEAEAAAAAERTPA 245

mukB

PRK04863

chromosome partition protein MukB;

4-250

3.42e-04

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 44.56 E-value: 3.42e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    4 DEQQRLTAQ--LALQ-RQKIQALTtSAKETQGKLAL---------AEARAQEEEQKATRLEKELQTQTTEFHQNQ----- 66
Cdd:PRK04863  401 DYQQALDVQqtRAIQyQQAVQALE-RAKQLCGLPDLtadnaedwlEEFQAKEQEATEELLSLEQKLSVAQAAHSQfeqay 479

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   67 ---DKIMAKLTNEDSQN------------RQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNsgimDE 131
Cdd:PRK04863  480 qlvRKIAGEVSRSEAWDvarellrrlreqRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDE----DE 555

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  132 VDELRkrvldmEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRIT-------ALEKLED---ALDKSKQEC 201
Cdd:PRK04863  556 LEQLQ------EELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPawlaaqdALARLREqsgEEFEDSQDV 629

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 295424124  202 YSLKCN-LEKEKMTTK---QLSEELESLNARIKELEAIESRLEKTEITLKDDL 250
Cdd:PRK04863  630 TEYMQQlLERERELTVerdELAARKQALDEEIERLSQPGGSEDPRLNALAERF 682

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

4-535

3.63e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 3.63e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    4 DEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEE--------EQKATRLEKELQTQTTEFHQNQDKI-MAKLT 74
Cdd:COG4913   295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNggdrleqlEREIERLERELEERERRRARLEALLaALGLP 374

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   75 NEDS------QNRQLRQKLAALSRQIDELE----ETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEG 144
Cdd:COG4913   375 LPASaeefaaLRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALG 454

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  145 KDE-------ELIKMEEQCRDLNKRLEK--------------------ETVQSKDFKLEVDKLSVRITALEKLEDALDKS 197
Cdd:COG4913   455 LDEaelpfvgELIEVRPEEERWRGAIERvlggfaltllvppehyaaalRWVNRLHLRGRLVYERVRTGLPDPERPRLDPD 534

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  198 kqecyslkcnlekekmttkQLSEELEslnarIKELEA---IESRLEKTeitlkddltklktLTVMLVDErktmSEKLKQT 274
Cdd:COG4913   535 -------------------SLAGKLD-----FKPHPFrawLEAELGRR-------------FDYVCVDS----PEELRRH 573

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  275 EdklQSTTSQLQAEQNKvtTVTEKlieETKRALKSK----TDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKN 350
Cdd:COG4913   574 P---RAITRAGQVKGNG--TRHEK---DDRRRIRSRyvlgFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQE 645

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  351 RLQSLEAIEKDfvknklnQDSSKSTAALHQEnnkIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKA 430
Cdd:COG4913   646 RREALQRLAEY-------SWDEIDVASAERE---IAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEI 715

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  431 QFLSQELEHAKMELAKYK-LAEKTESSHEQWLFRRLQE----------EEAKSGHLSREVDALKEKIHEymATEDLIchl 499
Cdd:COG4913   716 GRLEKELEQAEEELDELQdRLEAAEDLARLELRALLEErfaaalgdavERELRENLEERIDALRARLNR--AEEELE--- 790

                         570       580       590
                  ....*....|....*....|....*....|....*.
gi 295424124  500 qgdhSLLQKKLNQQENRNRDLGREIENLTKELERYR 535
Cdd:COG4913   791 ----RAMRAFNREWPAETADLDADLESLPEYLALLD 822

PRK05771

V-type ATP synthase subunit I; Validated

76-312

3.76e-04

V-type ATP synthase subunit I; Validated

Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 44.15 E-value: 3.76e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  76 EDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKinKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQ 155
Cdd:PRK05771  41 SNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVSVK--SLEELIKDVEEELEKIEKEIKELEEEISELENEIKE 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 156 CRDLNKRLEKetvqSKDFKLEVDKL-----------SVRITALEKLEDALDKSKQECYS--------------------- 203
Cdd:PRK05771 119 LEQEIERLEP----WGNFDLDLSLLlgfkyvsvfvgTVPEDKLEELKLESDVENVEYIStdkgyvyvvvvvlkelsdeve 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 204 ---LKCNLEKEKM-TTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVD---ERKTMSEKLKQTEd 276
Cdd:PRK05771 195 eelKKLGFERLELeEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEielERAEALSKFLKTD- 273

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 295424124 277 klqsTTSQLQAeqnkvtTVTEKLIEETKRALKSKTD 312
Cdd:PRK05771 274 ----KTFAIEG------WVPEDRVKKLKELIDKATG 299

PRK12704

phosphodiesterase; Provisional

104-253

3.85e-04

phosphodiesterase; Provisional

Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 44.00 E-value: 3.85e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 104 LRKAEEELQDIKDKINKgeygnsgimdEVDELRKRVLdMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVR 183
Cdd:PRK12704  33 IKEAEEEAKRILEEAKK----------EAEAIKKEAL-LEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRK 101

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 295424124 184 ITALEKLEDALDKSKQECYSLKCNLEK-----EKMTTKQLsEELESLNARIKElEAIESRLEKTEITLKDDLTKL 253
Cdd:PRK12704 102 LELLEKREEELEKKEKELEQKQQELEKkeeelEELIEEQL-QELERISGLTAE-EAKEILLEKVEEEARHEAAVL 174

Cast

pfam10174

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...

33-446

4.11e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.

Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 44.04 E-value: 4.11e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   33 KLALAEARAQEEEQKATRLEKELQTQTTEFHQNQdkimaKLTNEDSQNRQLRQKLAALSRQIDELEetnRSLRKAEEELQ 112
Cdd:pfam10174 186 RIAEAEMQLGHLEVLLDQKEKENIHLREELHRRN-----QLQPDPAKTKALQTVIEMKDTKISSLE---RNIRDLEDEVQ 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  113 DIKDKINKGEYGNSGIMDEVDELRKRVLDMEGK----DEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALE 188
Cdd:pfam10174 258 MLKTNGLLHTEDREEEIKQMEVYKSHSKFMKNKidqlKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  189 KLEDALdksKQECYSLKCNL-EKEKM---TTKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDER 264
Cdd:pfam10174 338 QRAAIL---QTEVDALRLRLeEKESFlnkKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKD 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  265 KTMSEkLKQTEDKLQSTTSQlqaEQNKVTTVTEKLIEETK--RALKSKTDAEEKMYsvTKERDDLRNKLKaeeekghDLL 342
Cdd:pfam10174 415 KQLAG-LKERVKSLQTDSSN---TDTALTTLEEALSEKERiiERLKEQREREDRER--LEELESLKKENK-------DLK 481

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  343 SKVTILKNRLQSLEAIEKDFVKNKLNQDSSKStaalhQENNKIKELSQEVENlklKLKDMKAIEDDLMKTEdEYETLERR 422
Cdd:pfam10174 482 EKVSALQPELTEKESSLIDLKEHASSLASSGL-----KKDSKLKSLEIAVEQ---KKEECSKLENQLKKAH-NAEEAVRT 552

                         410       420
                  ....*....|....*....|....
gi 295424124  423 YANERDKAQFLSQELEHAKMELAK 446
Cdd:pfam10174 553 NPEINDRIRLLEQEVARYKEESGK 576

Smc

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...

1-169

4.18e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];

Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.16 E-value: 4.18e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   1 MVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQtqtTEFHQNQDKIMAKLTNEDSQN 80
Cdd:COG1196  662 LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL---EEELEEEALEEQLEAEREELL 738

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  81 RQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLN 160
Cdd:COG1196  739 EELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPVNLLAIEEYEELEERYDFLSEQREDLEEARETLEEAI 818


                 ....*....
gi 295424124 161 KRLEKETVQ 169
Cdd:COG1196  819 EEIDRETRE 827

PRK03918

DNA double-strand break repair ATPase Rad50;

90-247

4.95e-04

DNA double-strand break repair ATPase Rad50;

Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.90 E-value: 4.95e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  90 LSRQIDELEETNR---SLRKAEEELQDIKDKINKGEygnsgimDEVDELRKRVLDMEGKDEELikmEEQCRDLNKRLEKE 166
Cdd:PRK03918 590 LEERLKELEPFYNeylELKDAEKELEREEKELKKLE-------EELDKAFEELAETEKRLEEL---RKELEELEKKYSEE 659

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 167 TVQSKDFKLEvdKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITL 246
Cdd:PRK03918 660 EYEELREEYL--ELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALL 737


                 .
gi 295424124 247 K 247
Cdd:PRK03918 738 K 738

DR0291

COG1579

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...

131-317

5.51e-04

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];

Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 42.60 E-value: 5.51e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 131 EVDELRKRVLDMEgkdEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKLSvriTALEKLEDALDKSKqecyslkcnlek 210
Cdd:COG1579   18 ELDRLEHRLKELP---AELAELEDELAALEARLEAAKTELEDLEKEIKRLE---LEIEEVEARIKKYE------------ 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 211 EKMTTKQLSEELESLNariKELEAIESRLEKTEITLKDdltklktltvmLVDERKTMSEKLKQTEDKLQSTTSQLQAEQN 290
Cdd:COG1579   80 EQLGNVRNNKEYEALQ---KEIESLKRRISDLEDEILE-----------LMERIEELEEELAELEAELAELEAELEEKKA 145

                        170       180
                 ....*....|....*....|....*..
gi 295424124 291 KVTTVTEKLIEETKRALKSKTDAEEKM 317
Cdd:COG1579  146 ELDEELAELEAELEELEAEREELAAKI 172

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

4-155

5.51e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 5.51e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   4 DEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLE-----KELQTQTTEFHQNQDKIMAKLTNEDS 78
Cdd:COG3206  212 EEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLqspviQQLRAQLAELEAELAELSARYTPNHP 291

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 295424124  79 QNRQLRQKLAALSRQIDelEETNRSLRKAEEELQDIKDKINKgeygnsgIMDEVDELRKRVLDMEGKDEELIKMEEQ 155
Cdd:COG3206  292 DVIALRAQIAALRAQLQ--QEAQRILASLEAELEALQAREAS-------LQAQLAQLEARLAELPELEAELRRLERE 359

PTZ00121

MAEBL; Provisional

55-564

5.81e-04

MAEBL; Provisional

Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 43.98 E-value: 5.81e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   55 LQTQTTEFHQNQD-KIMAKLTNEDSQNRQLRQklaalsRQIDELEETNRSLRKAEEELQDIKDKINKGEYGNsgimDEVD 133
Cdd:PTZ00121 1013 LTANTIDFNQNFNiEKIEELTEYGNNDDVLKE------KDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKD----FDFD 1082

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  134 ELRKRVLDmEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDklSVRITALEKLEDAldkskqecyslkcnlekekm 213
Cdd:PTZ00121 1083 AKEDNRAD-EATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAED--ARKAEEARKAEDA-------------------- 1139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  214 ttKQLSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKtmSEKLKQTEDKLQSTTSQLQAEQNKVT 293
Cdd:PTZ00121 1140 --RKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRK--AEELRKAEDARKAEAARKAEEERKAE 1215

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  294 TV----TEKLIEETKRALKSKTDAEEKMySVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIEKDFVKNKLNQ 369
Cdd:PTZ00121 1216 EArkaeDAKKAEAVKKAEEAKKDAEEAK-KAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADE 1294

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  370 ----------DSSKSTAalhQENNKIKELSQEVENLKLKLKDMK------AIEDDLMKTEDEYETLERRYANERDKAQFL 433
Cdd:PTZ00121 1295 akkaeekkkaDEAKKKA---EEAKKADEAKKKAEEAKKKADAAKkkaeeaKKAAEAAKAEAEAAADEAEAAEEKAEAAEK 1371

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  434 SQELEHAKMELAKYKLAEKT---ESSHEQWLFRRLQEEEAKSGHLSREVDALKEKIHEYMATEDLichlqgDHSLLQKKL 510
Cdd:PTZ00121 1372 KKEEAKKKADAAKKKAEEKKkadEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEA------KKKAEEAKK 1445

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....
gi 295424124  511 NQQENRNRDLGREIENLTKELERYRHFSKSLRPSLNERRISDPQVFSKEVQTEA 564
Cdd:PTZ00121 1446 ADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKA 1499

PspA

COG1842

Phage shock protein A [Transcription, Signal transduction mechanisms];

5-165

6.31e-04

Phage shock protein A [Transcription, Signal transduction mechanisms];

Pssm-ID: 441447 [Multi-domain] Cd Length: 217 Bit Score: 42.12 E-value: 6.31e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   5 EQQRLTAQLALQRQKIQALTTSAKE--TQGKLALAEArAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLtnedsqnRQ 82
Cdd:COG1842   52 NQKRLERQLEELEAEAEKWEEKARLalEKGREDLARE-ALERKAELEAQAEALEAQLAQLEEQVEKLKEAL-------RQ 123

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  83 LRQKLAALSRQIDELeetnrslrKAEEELQDIKDKINK--GEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQcRDLN 160
Cdd:COG1842  124 LESKLEELKAKKDTL--------KARAKAAKAQEKVNEalSGIDSDDATSALERMEEKIEEMEARAEAAAELAAG-DSLD 194


                 ....*
gi 295424124 161 KRLEK 165
Cdd:COG1842  195 DELAE 199

CagA_N

pfam18971

CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial ...

6-292

7.13e-04

CagA protein; The Helicobacter pylori type IV secretion effector CagA is a major bacterial virulence determinant and critical for gastric carcinogenesis. X-ray crystallographic analysis of the N-terminal CagA fragment (residues 1-876) revealed that the region has a structure comprised of three discrete domains. Domain I constitutes a mobile CagA N terminus, while Domain II tethers CagA to the plasma membrane by interacting with membrane phosphatidylserine. Domain III interacts intramolecularly with the intrinsically disordered C-terminal region, and this interaction potentiates the pathogenic scaffold/hub function of CagA.

Pssm-ID: 408741 [Multi-domain] Cd Length: 876 Bit Score: 43.61 E-value: 7.13e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    6 QQRLTAQ-LALQRQK--IQALTTSAKETQGKL-----ALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNED 77
Cdd:pfam18971 562 ENKLTAKgLSLQEANklIKDFLSSNKELAGKAlnfnkAVAEAKSTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKS 641

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   78 SQNRQLRQKLAALSrQIDEL-----EETNR---------SLRKAEEELQDIKDKINKGEYGNSGIMDEVDelrkrvldmE 143
Cdd:pfam18971 642 GNKNKMEAKAQANS-QKDEIfalinKEANRdaraiaytqNLKGIKRELSDKLEKISKDLKDFSKSFDEFK---------N 711

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  144 GKDEELIKMEEQCRDLNKRLeKETVQSKDFKLEVDKLSvriTALEKLEDALDKSKQECYSLKCNLE---KEKMTTKQLSE 220
Cdd:pfam18971 712 GKNKDFSKAEETLKALKGSV-KDLGINPEWISKVENLN---AALNEFKNGKNKDFSKVTQAKSDLEnsvKDVIINQKVTD 787

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 295424124  221 ELESLNARIKELEAIE--SRLEKTeitlkddLTKLKTLTvmlvdeRKTMSEKLKQTEDKLQSTTSQL-QAEQNKV 292
Cdd:pfam18971 788 KVDNLNQAVSVAKAMGdfSRVEQV-------LADLKNFS------KEQLAQQAQKNEDFNTGKNSELyQSVKNSV 849

PRK04778

septation ring formation regulator EzrA; Provisional

81-422

7.25e-04

septation ring formation regulator EzrA; Provisional

Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 43.29 E-value: 7.25e-04

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  81 RQLRQKLAALSRQIDELEETNRSLRkaeEELQDIK--DKINKGEYGnsGIMDEVDELRKRVLD--------MEGKDEELI 150
Cdd:PRK04778 101 RKAKHEINEIESLLDLIEEDIEQIL---EELQELLesEEKNREEVE--QLKDLYRELRKSLLAnrfsfgpaLDELEKQLE 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 151 KMEEQ---------------CRDLNKRLEKETVQSKDFKLEVDKLSVRITA-----LEKLEDALDKSKQECYSLK-CNLE 209
Cdd:PRK04778 176 NLEEEfsqfveltesgdyveAREILDQLEEELAALEQIMEEIPELLKELQTelpdqLQELKAGYRELVEEGYHLDhLDIE 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 210 KEkmtTKQLSEELESLNARIKELE---------AIESRL-----------------EKTEITLKDDLTKLKTLTVMLVDE 263
Cdd:PRK04778 256 KE---IQDLKEQIDENLALLEELDldeaeekneEIQERIdqlydilerevkarkyvEKNSDTLPDFLEHAKEQNKELKEE 332

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 264 RKTMSEKLKQTEDKLQsTTSQLQAEQNKVTTVTEKLIEEtkralkskTDAEEKMYSVTKER-DDLRNKLKAEEEKGHDll 342
Cdd:PRK04778 333 IDRVKQSYTLNESELE-SVRQLEKQLESLEKQYDEITER--------IAEQEIAYSELQEElEEILKQLEEIEKEQEK-- 401

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 343 skvtiLKNRLQSLEAIEKDfVKNKLNQ-DSSKSTAALHQEN------------------NKIKELSQEVENLKLklkDMK 403
Cdd:PRK04778 402 -----LSEMLQGLRKDELE-AREKLERyRNKLHEIKRYLEKsnlpglpedylemffevsDEIEALAEELEEKPI---NME 472

                        410
                 ....*....|....*....
gi 295424124 404 AIEDDLMKTEDEYETLERR 422
Cdd:PRK04778 473 AVNRLLEEATEDVETLEEE 491

sbcc

TIGR00618

exonuclease SbcC; All proteins in this family for which functions are known are part of an ...

28-579

8.20e-04

Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.42 E-value: 8.20e-04

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    28 KETQGKLALAEARAQEEEQkatrLEKELQTQTTEFHQNQDKIMAKLTNEdsqNRQLRQKLAALSRQIDELEETNRSLRKA 107
Cdd:TIGR00618  190 KSLHGKAELLTLRSQLLTL----CTPCMPDTYHERKQVLEKELKHLREA---LQQTQQSHAYLTQKREAQEEQLKKQQLL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   108 EEELQDIKDKINkgEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRL-EKETVQSKDFKLEVDKLSVRiTA 186
Cdd:TIGR00618  263 KQLRARIEELRA--QEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELqSKMRSRAKLLMKRAAHVKQQ-SS 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   187 LEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELEsLNARIKELEAIESRLEKTEITLKDDLTKLKTLtVMLVDERKT 266
Cdd:TIGR00618  340 IEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHT-LTQHIHTLQQQKTTLTQKLQSLCKELDILQRE-QATIDTRTS 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   267 MSEKLKQtedKLQSTTSQLQAEQnKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERD----DLRNKLKAEEEKGhdll 342
Cdd:TIGR00618  418 AFRDLQG---QLAHAKKQQELQQ-RYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREqqlqTKEQIHLQETRKK---- 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   343 skvTILKNRLQSLEAIEKDFvknklnqdsSKSTAALHQEnnkikelSQEVENLKLKLKDMKAIEDDLMKTEDEYETLERR 422
Cdd:TIGR00618  490 ---AVVLARLLELQEEPCPL---------CGSCIHPNPA-------RQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQ 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   423 YANERDKAQFLSQELEHAKMELAkyKLAEKTESSHE-------------QWLFRRLQEEEAKSGHLSREVDALKEKIHEY 489
Cdd:TIGR00618  551 LTSERKQRASLKEQMQEIQQSFS--ILTQCDNRSKEdipnlqnitvrlqDLTEKLSEAEDMLACEQHALLRKLQPEQDLQ 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   490 mateDLICHLQGDHSLLQKKLNQqenrnrdLGREIENLTKELERYRHF-SKSLRPSLNERRISDPQVFSKEVQTEAADSE 568
Cdd:TIGR00618  629 ----DVRLHLQQCSQELALKLTA-------LHALQLTLTQERVREHALsIRVLPKELLASRQLALQKMQSEKEQLTYWKE 697

                          570
                   ....*....|.
gi 295424124   569 PPDYKSLIPLE 579
Cdd:TIGR00618  698 MLAQCQTLLRE 708

HOOK

pfam05622

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ...

42-370

9.30e-04

HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.

Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 42.75 E-value: 9.30e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   42 QEEEQKATRLEKELQT---QTTEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEEL---QDIK 115
Cdd:pfam05622 172 EEELKKANALRGQLETykrQVQELHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERLIIERDTLRETNEELrcaQLQQ 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  116 DKINKGEYGNSGIMDEVDELRKRVLDMEGKdEELIKMEEQcrdlNKRL-EKETVQSKDfklevdklsvRITALEKLedal 194
Cdd:pfam05622 252 AELSQADALLSPSSDPGDNLAAEIMPAEIR-EKLIRLQHE----NKMLrLGQEGSYRE----------RLTELQQL---- 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  195 dkskqecyslkcnLEKEKMTTKQLSEELESLNARIKELEAiesRLEKTEITLKDDLTKLKTlTVMLVDERKTMSEKLKQT 274
Cdd:pfam05622 313 -------------LEDANRRKNELETQNRLANQRILELQQ---QVEELQKALQEQGSKAED-SSLLKQKLEEHLEKLHEA 375

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  275 EDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTD----AEE--KMY-----SVTKERDDLRNKLKAEEekghdlls 343
Cdd:pfam05622 376 QSELQKKKEQIEELEPKQDSNLAQKIDELQEALRKKDEdmkaMEEryKKYvekakSVIKTLDPKQNPASPPE-------- 447

                         330       340       350
                  ....*....|....*....|....*....|.
gi 295424124  344 kVTILKNRLQ----SLEAIEKDFVKNKLNQD 370
Cdd:pfam05622 448 -IQALKNQLLekdkKIEHLERDFEKSKLQRE 477

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

7-533

9.46e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.98 E-value: 9.46e-04

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    7 QRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQTTEFHQNQDKIMAKLTNEDSQNRQLRQK 86
Cdd:COG4913   341 EQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRE 420

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   87 LAALSRQIDELEETNRSLrkaEEELQDIKDKINKgeygNSGImDEVD-----ELrkrvLDMEGKDEE------------- 148
Cdd:COG4913   421 LRELEAEIASLERRKSNI---PARLLALRDALAE----ALGL-DEAElpfvgEL----IEVRPEEERwrgaiervlggfa 488

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  149 --LIKMEEQCRDLNKRLEketvqSKDFKLEVDKLSVRITALEKLEDALDKSkqecySLkcnleKEKMTTKQ--LSEELES 224
Cdd:COG4913   489 ltLLVPPEHYAAALRWVN-----RLHLRGRLVYERVRTGLPDPERPRLDPD-----SL-----AGKLDFKPhpFRAWLEA 553

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  225 LNARIKELEAIES----RLEKTEITL------------KDDLTKLKTLTVMLVDER---KTMSEKLKQTEDKLQSTTSQL 285
Cdd:COG4913   554 ELGRRFDYVCVDSpeelRRHPRAITRagqvkgngtrheKDDRRRIRSRYVLGFDNRaklAALEAELAELEEELAEAEERL 633

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  286 QAEQNKVTTVTEKLieETKRALKSKTDAEEKMYSVTKERDDLRNKLkAEEEKGHDLLSKvtiLKNRLQSLEAIEKDFVKn 365
Cdd:COG4913   634 EALEAELDALQERR--EALQRLAEYSWDEIDVASAEREIAELEAEL-ERLDASSDDLAA---LEEQLEELEAELEELEE- 706

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  366 klnqdsskstaALHQENNKIKELSQEVENLKLKLKDMKAIEDDL--MKTEDEYETLERRYAN------ERDKAQFLSQEL 437
Cdd:COG4913   707 -----------ELDELKGEIGRLEKELEQAEEELDELQDRLEAAedLARLELRALLEERFAAalgdavERELRENLEERI 775

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  438 EHAKMELAkyKLAEKTESSHEQwlFRRLQEEEAksGHLSREVDALKE--KIHEYMATEDLICHlqgdhsllQKKLNQQEN 515
Cdd:COG4913   776 DALRARLN--RAEEELERAMRA--FNREWPAET--ADLDADLESLPEylALLDRLEEDGLPEY--------EERFKELLN 841

                         570
                  ....*....|....*...
gi 295424124  516 RNrdLGREIENLTKELER 533
Cdd:COG4913   842 EN--SIEFVADLLSKLRR 857

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

16-541

1.04e-03

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 42.85 E-value: 1.04e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    16 QRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKE-------LQTQTTEFHQNQD-----------------KIMA 71
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEknalqeqLQAETELCAEAEEmrarlaarkqeleeilhELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    72 KLTNEDSQNRQL-------RQKLAALSRQIDELEETNRSLR----KAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVL 140
Cdd:pfam01576   83 RLEEEEERSQQLqnekkkmQQHIQDLEEQLDEEEAARQKLQlekvTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERIS 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   141 DME---GKDEELIKM--------EEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITAL-----------EKLEDALDKSK 198
Cdd:pfam01576  163 EFTsnlAEEEEKAKSlsklknkhEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLqeqiaelqaqiAELRAQLAKKE 242

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   199 QECYSLKCNLEKEKMTTKQLSEELESLNARIKELE-------AIESRLEKTEITLKDDLTKLKTLTVMLVD--------- 262
Cdd:pfam01576  243 EELQAALARLEEETAQKNNALKKIRELEAQISELQedleserAARNKAEKQRRDLGEELEALKTELEDTLDttaaqqelr 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   263 -ERKTMSEKLKQT-EDKLQSTTSQLQAEQNKVTTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHD 340
Cdd:pfam01576  323 sKREQEVTELKKAlEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQD 402

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   341 LLSKVTILKNRLQSLEA--IEKDFVKNKLNQDSSKS-------TAALHQENNKIKELSQEVENLKLKLKDMK-------- 403
Cdd:pfam01576  403 SEHKRKKLEGQLQELQArlSESERQRAELAEKLSKLqselesvSSLLNEAEGKNIKLSKDVSSLESQLQDTQellqeetr 482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   404 ---AIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLfrrlqeEEAKSgHLSREVD 480
Cdd:pfam01576  483 qklNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEAL------EEGKK-RLQRELE 555

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 295424124   481 ALKEKIHEYMATEDlichlqgdhsllqkKLNQQENRnrdLGREIENLTKELERYRHFSKSL 541
Cdd:pfam01576  556 ALTQQLEEKAAAYD--------------KLEKTKNR---LQQELDDLLVDLDHQRQLVSNL 599

CALCOCO1

pfam07888

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...

160-500

1.21e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.

Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.57 E-value: 1.21e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  160 NKRLEKETVQSKDFKLEVDKLSVRITA-LEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESL-------NARIKE 231
Cdd:pfam07888  54 NRQREKEKERYKRDREQWERQRRELESrVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALlaqraahEARIRE 133

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  232 LEAIESRLEKTEITLKDDLTKLKTLTVMLV-------DERKTMSEKLKQTEDKLQSTTSQLQ------AEQNKVTTVTEK 298
Cdd:pfam07888 134 LEEDIKTLTQRVLERETELERMKERAKKAGaqrkeeeAERKQLQAKLQQTEEELRSLSKEFQelrnslAQRDTQVLQLQD 213

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  299 LIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEkghdllsKVTILKNRLQSLEAIEkdfvknklnqdsSKSTAAL 378
Cdd:pfam07888 214 TITTLTQKLTTAHRKEAENEALLEELRSLQERLNASER-------KVEGLGEELSSMAAQR------------DRTQAEL 274

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  379 HQENNKIKELSQEVENLKLKLKDMKAieddlmKTEDEYETLERRYANERDKAQFLSQEL---------EHAKMELAKYKL 449
Cdd:pfam07888 275 HQARLQAAQLTLQLADASLALREGRA------RWAQERETLQQSAEADKDRIEKLSAELqrleerlqeERMEREKLEVEL 348

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|...
gi 295424124  450 AEKTESSHEQW--LFRRLQEEEAKSGHLSREVDALKEKIHEYMateDLICHLQ 500
Cdd:pfam07888 349 GREKDCNRVQLseSRRELQELKASLRVAQKEKEQLQAEKQELL---EYIRQLE 398

COG2433

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

44-180

1.22e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 42.54 E-value: 1.22e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  44 EEQKATRLEKELQTQTTEFHQNQdkimAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQdikdkinkgey 123
Cdd:COG2433  383 EELIEKELPEEEPEAEREKEHEE----RELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLE----------- 447

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 295424124 124 gnsgimDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDKL 180
Cdd:COG2433  448 ------RELSEARSEERREIRKDREISRLDREIERLERELEEERERIEELKRKLERL 498

Myosin_tail_1

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...

21-420

1.30e-03

Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 42.47 E-value: 1.30e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    21 QALTTSAKETQGKLALAEARAQEEEQKATRLEKELQtqttefhqnqdKIMAKLTNEDSQNRQLRQKLAALSrqiDELEET 100
Cdd:pfam01576  380 QALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQ-----------ELQARLSESERQRAELAEKLSKLQ---SELESV 445

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   101 NRSLRKAEEELQDIKDKINKGEYGNSGIMDEVDELRKRVLDMEGKdeeLIKMEEQCRDLNKRLEKETVQSKDFKLEVDKL 180
Cdd:pfam01576  446 SSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTR---LRQLEDERNSLQEQLEEEEEAKRNVERQLSTL 522

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   181 SVRITALEKledaldksKQECYSLkcNLEKEKMTTKQLSEELESLNARIKELEAIESRLEKTEITLKDDltkLKTLTVML 260
Cdd:pfam01576  523 QAQLSDMKK--------KLEEDAG--TLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQE---LDDLLVDL 589

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   261 VDERKTMSeklkqTEDKLQSTTSQLQAEQNkvtTVTEKLIEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEkghd 340
Cdd:pfam01576  590 DHQRQLVS-----NLEKKQKKFDQMLAEEK---AISARYAEERDRAEAEAREKETRALSLARALEEALEAKEELER---- 657

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   341 llskvtilKNRLQSLEAieKDFVKNKlnQDSSKStaaLHQENNKIKELSQEVENLKLKLKDMkaiEDDLMKTEDEYETLE 420
Cdd:pfam01576  658 --------TNKQLRAEM--EDLVSSK--DDVGKN---VHELERSKRALEQQVEEMKTQLEEL---EDELQATEDAKLRLE 719

FPP

pfam05911

Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ...

67-336

1.34e-03

Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.

Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 42.35 E-value: 1.34e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   67 DKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELqdikdkinkgeygnSGIMDEVDELRKRVLDMEGKD 146
Cdd:pfam05911 562 SKEALDDQDTSSDSSELSEVLQQFSATCNDVLSGKADLEDFVLEL--------------SHILDWISNHCFSLLDVSSME 627

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  147 EELIKMEeqCRDLNKRLEKETVQSKDFKLEVDKLS--VRITALEKLEDALDKSKQ-ECYSLKCNLEKEKMTTKQLSEELE 223
Cdd:pfam05911 628 DEIKKHD--CIDKVTLSENKVAQVDNGCSEIDNLSsdPEIPSDGPLVSGSNDLKTeENKRLKEEFEQLKSEKENLEVELA 705

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  224 SLNARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEET 303
Cdd:pfam05911 706 SCTENLESTKSQLQESEQLIAELRSELASLKESNSLAETQLKCMAESYEDLETRLTELEAELNELRQKFEALEVELEEEK 785

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 295424124  304 K---RALKSKTDAEEKMYSVTKER------DDLRNKLKAEEE 336
Cdd:pfam05911 786 NcheELEAKCLELQEQLERNEKKEssncdaDQEDKKLQQEKE 827

COG4913

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

81-330

1.87e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];

Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.21 E-value: 1.87e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   81 RQLRQKLAALSRQIDELEETNRSLRKAEEE---LQDIKDKINKGEyGNSGIMDEVDELRKRvLDMEGKDEELIKMEEQCR 157
Cdd:COG4913   221 PDTFEAADALVEHFDDLERAHEALEDAREQielLEPIRELAERYA-AARERLAELEYLRAA-LRLWFAQRRLELLEAELE 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  158 DLNKRLEKETVQSKDFKLEVDKLSVRitaLEKLEDALDKSKQEcyslkcNLEkekmttkQLSEELESLNARIKELEAIES 237
Cdd:COG4913   299 ELRAELARLEAELERLEARLDALREE---LDELEAQIRGNGGD------RLE-------QLEREIERLERELEERERRRA 362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  238 RLEKTeitlkddltkLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTtvteklieetkRALKSKTDAEEKM 317
Cdd:COG4913   363 RLEAL----------LAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALA-----------EAEAALRDLRREL 421

                         250
                  ....*....|...
gi 295424124  318 YSVTKERDDLRNK 330
Cdd:COG4913   422 RELEAEIASLERR 434

mukB

PRK04863

chromosome partition protein MukB;

4-369

1.89e-03

chromosome partition protein MukB;

Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.25 E-value: 1.89e-03

                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124    4 DEQQRLTAQLALQRQKIQALTTSAKETQGK-LALAEARAQEEEQKATRleKELQTQTTEfhqnqdkimakLTNEDSQNRQ 82
Cdd:PRK04863  796 EELAERYATLSFDVQKLQRLHQAFSRFIGShLAVAFEADPEAELRQLN--RRRVELERA-----------LADHESQEQQ 862

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   83 LRQKLAALSRQIDELEETNRSLRKAEEElqdikdkinkgeygnsGIMDEVDELRkrvldmegkdEELIKMEEQCRDLNK- 161
Cdd:PRK04863  863 QRSQLEQAKEGLSALNRLLPRLNLLADE----------------TLADRVEEIR----------EQLDEAEEAKRFVQQh 916

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  162 -----RLEKE--TVQSKDFKLEVDKLSVritalEKLEDALDKSKQECYSLKCNLEK---------EKMTTKQlSEELESL 225
Cdd:PRK04863  917 gnalaQLEPIvsVLQSDPEQFEQLKQDY-----QQAQQTQRDAKQQAFALTEVVQRrahfsyedaAEMLAKN-SDLNEKL 990

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  226 NARIKELEAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKLIEETKR 305
Cdd:PRK04863  991 RQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEERARARRDELHARLS 1070

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 295424124  306 ALKSKTDAEEKMYSVTK-ERDDLRNKLKAEEEKGHDLLSKVTILKNRLQS-LEAIEKDFVKNKLNQ 369
Cdd:PRK04863 1071 ANRSRRNQLEKQLTFCEaEMDNLTKKLRKLERDYHEMREQVVNAKAGWCAvLRLVKDNGVERRLHR 1136

GumC

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

75-297

1.98e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];

Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.93 E-value: 1.98e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  75 NEDSQNRQLRQKLAALSRQIDELEEtnrSLRKAEEELQDIKDK---INKGEYGNSgIMDEVDELRKRVLDMEgkdEELIK 151
Cdd:COG3206  165 NLELRREEARKALEFLEEQLPELRK---ELEEAEAALEEFRQKnglVDLSEEAKL-LLQQLSELESQLAEAR---AELAE 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 152 MEEQCRDLNKRLEKETVQSKDFK--LEVDKLSVRITALEKLEDALDKS-----------KQECYSLKCNLEKE-KMTTKQ 217
Cdd:COG3206  238 AEARLAALRAQLGSGPDALPELLqsPVIQQLRAQLAELEAELAELSARytpnhpdvialRAQIAALRAQLQQEaQRILAS 317

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 218 LSEELESLNARIKELEAIESRLEKTEITLKDDLTKLKTLTvmlvDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTE 297
Cdd:COG3206  318 LEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE----REVEVARELYESLLQRLEEARLAEALTVGNVRVIDP 393

COG2433

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

88-252

2.01e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];

Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.77 E-value: 2.01e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124  88 AALSRQI-----DELEETNRSLRKAEEELQDIKDKINKGEygnsgimDEVDELRKRVLDMEG----KDEELIKMEEQCRD 158
Cdd:COG2433  380 EALEELIekelpEEEPEAEREKEHEERELTEEEEEIRRLE-------EQVERLEAEVEELEAeleeKDERIERLERELSE 452

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124 159 LNKRLEKETVQSKdfklEVDKLSVRITALEKLedaldkskqecyslkcnLEKEKMTtkqlSEELESLNARIKELEAIESR 238
Cdd:COG2433  453 ARSEERREIRKDR----EISRLDREIERLERE-----------------LEEERER----IEELKRKLERLKELWKLEHS 507

                        170
                 ....*....|....
gi 295424124 239 LEKTEITLKDDLTK 252
Cdd:COG2433  508 GELVPVKVVEKFTK 521

PRK09039

peptidoglycan -binding protein;

7-137

2.18e-03

peptidoglycan -binding protein;

Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 41.10 E-value: 2.18e-03

                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   7 QRLTAQLALQRQKIQALTTSAKETQGKLALAEA--------------RAQEEEQKATRLEKELQTQTTEFHQNQDKImaK 72
Cdd:PRK09039  63 AELADLLSLERQGNQDLQDSVANLRASLSAAEAersrlqallaelagAGAAAEGRAGELAQELDSEKQVSARALAQV--E 140

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 295424124  73 LTNEdsQNRQLRQKLAALSRQIDELEETNRSlrkAEEELQDIkdkinkGEYGNSGIMDEVDELRK 137
Cdd:PRK09039 141 LLNQ--QIAALRRQLAALEAALDASEKRDRE---SQAKIADL------GRRLNVALAQRVQELNR 194

rad50

rad50; All proteins in this family for which functions are known are involvedin recombination, ...

153-545

2.19e-03

Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.96 E-value: 2.19e-03

                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   153 EEQCRDLNKRLEKETVQSKDFKLEVDKLSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEEleslnarikEL 232
Cdd:TIGR00606  233 LESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE---------QL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   233 EAIESRLEKTEITLKDDLTKLKTLTVMLVDERKTMSEKlkQTEDKLQSTTSQLQAEQNKVTTVTEKLiEETKRALKSKTD 312
Cdd:TIGR00606  304 NDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQE--KTELLVEQGRLQLQADRHQEHIRARDS-LIQSLATRLELD 380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   313 AEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVT---ILKNRLQSLEAIEKDFVKNKLNQDSSKSTAALHQENNKIKELS 389
Cdd:TIGR00606  381 GFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCadlQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVI 460

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   390 QEVENLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEE 469
Cdd:TIGR00606  461 KELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEML 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 295424124   470 AKS---------GHLSREVDALKEKIHEYMATEDLICHLQGdhslLQKKLNQQENRNRDLGREIENLTKELERYRHFSKS 540
Cdd:TIGR00606  541 TKDkmdkdeqirKIKSRHSDELTSLLGYFPNKKQLEDWLHS----KSKEINQTRDRLAKLNKELASLEQNKNHINNELES 616


                   ....*
gi 295424124   541 LRPSL 545
Cdd:TIGR00606  617 KEEQL 621

GumC