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Conserved domains on  [gi|294474363|gb|ADE83752|]
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lipid A biosynthesis acyltransferase [Prevotella ruminicola 23]

Protein Classification

lysophospholipid acyltransferase family protein( domain architecture ID 10787785)

lysophospholipid acyltransferase (LPLAT) family protein may act as an acyltransferase of a de novo or remodeling pathway of glycerophospholipid biosynthesis, catalyzing the incorporation of an acyl group from either acyl-CoAs or acyl-acyl carrier proteins (acyl-ACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 11-286 1.00e-83

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


:

Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 253.96  E-value: 1.00e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  11 VWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYRIERGFYHFFCDYIVESVKLMTMTPENL 90
Cdd:COG1560    1 LLRLLRLLPLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  91 KRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEWitsLPLWMKS-DAQLGQIYHPIENKDFDRLFLRSRQRMGAVCIPMQ 169
Cdd:COG1560   81 RKRVEVEGLEHLEAALAEGRGVILLTPHFGNWEL---AGAALALrGYPVTAVYRPLKNPLLDRLIRRGRERFGGELIPRK 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 170 DTLRRMVeyRRAKQPIVIGFISDQKPHWVNiHHWIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRRVKRGY-YEAEVIPM 248
Cdd:COG1560  158 DGVRALL--RALRKGGIVGLLPDQDPGRKS-GVFVPFFGVPAATPTGPARLARRTGAPVVPVFARRLPDGRgYRLEIEPP 234

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 294474363 249 TREPQQlKDYELTDMYFDLLEKSIKRAPEFWLWSHDRW 286
Cdd:COG1560  235 LEDFSE-DVEADTQRLNRALEAWIREHPEQWLWLHRRW 271
 
Name Accession Description Interval E-value
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 11-286 1.00e-83

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 253.96  E-value: 1.00e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  11 VWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYRIERGFYHFFCDYIVESVKLMTMTPENL 90
Cdd:COG1560    1 LLRLLRLLPLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  91 KRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEWitsLPLWMKS-DAQLGQIYHPIENKDFDRLFLRSRQRMGAVCIPMQ 169
Cdd:COG1560   81 RKRVEVEGLEHLEAALAEGRGVILLTPHFGNWEL---AGAALALrGYPVTAVYRPLKNPLLDRLIRRGRERFGGELIPRK 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 170 DTLRRMVeyRRAKQPIVIGFISDQKPHWVNiHHWIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRRVKRGY-YEAEVIPM 248
Cdd:COG1560  158 DGVRALL--RALRKGGIVGLLPDQDPGRKS-GVFVPFFGVPAATPTGPARLARRTGAPVVPVFARRLPDGRgYRLEIEPP 234

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 294474363 249 TREPQQlKDYELTDMYFDLLEKSIKRAPEFWLWSHDRW 286
Cdd:COG1560  235 LEDFSE-DVEADTQRLNRALEAWIREHPEQWLWLHRRW 271
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 91-287 3.16e-47

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 157.76  E-value: 3.16e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  91 KRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEWitsLPLWM-KSDAQLGQIYHPIENKDFDRLFLRSRQRMGAVCIPMQ 169
Cdd:cd07984    1 LKRVEREGLEHLEAALAKGKGVILLTAHFGNWEL---AGLALaLLGYPVTVVYRPLKNPLLDRLITRGRERFGARLIPRG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 170 DTLRRMVEYRRAKQpiVIGFISDQKPHWvNIHHWIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRRVKRGYYEAEVIPMT 249
Cdd:cd07984   78 GGLRELIRALKKGE--IVGILPDQDPGR-KGGVFVPFFGRPAATPTGPARLALKTGAPVVPAFAYRLPGGGYRIEFEPPL 154

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 294474363 250 REPQQLKDYELTDMYFDLLEKSIKRAPEFWLWSHDRWK 287
Cdd:cd07984  155 ENPPSEDVEEDTQRLNDALEAAIREHPEQWLWFHRRWK 192
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
4-288 2.66e-36

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 132.08  E-value: 2.66e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363    4 LYYIVLAVWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYRIERGFYHFFCDYIVESVKLM 83
Cdd:pfam03279  14 LDWLGIAVLRLLALLPYSALRRIGKGLGRLAGRFLKRRRKIARRNLALCFPEMSEAEREQIIDKSFASVGRAIVETGRVW 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   84 TMTPENLKRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEwitsLP-LWMKSDAQ-LGQIYHPIENKDFDRLFLRSRQRM 161
Cdd:pfam03279  94 FWPDSRIAKRFEVIGLEHIKEALAQGRGAILVGPHFGNWD----LGgRVLGQQYPgMAVYRPNLKNPLLDWLQTSGRERF 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  162 GAVCIPMQDTLRRMVeyRRAKQPIVIGFISDQKpHWVNIHHWIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRRVKRG-Y 240
Cdd:pfam03279 170 GGRMLPRQNGIKGLI--KALRKGEVVWYLPDQD-LGRKDSVFVPFFGVPAATTTGPAKLALKTKAAVIPVFPIRNGDGsG 246

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 294474363  241 YEAEVIPMTREPQQLKDYELTDMYFDLLEKSIKRAPEFWLWSHDRWKR 288
Cdd:pfam03279 247 YTVIVHPALDLTITDDVEQIAQAMNQIVEKFIMPAPEQYFWLHRRWKT 294
PRK08419 PRK08419
lipid A biosynthesis lauroyl acyltransferase; Reviewed
 6-292 2.79e-19

lipid A biosynthesis lauroyl acyltransferase; Reviewed


Pssm-ID: 181420 [Multi-domain]  Cd Length: 298  Bit Score: 86.23  E-value: 2.79e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   6 YIVLAVWYVFS----LLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPE-KTDDERYRIERGFYHFFCDYIVESV 80
Cdd:PRK08419   4 RIYLSLFYILKfflaKMPHCIFLRLAKALAFIMRYLDKKRRKIAKANLDFCFGEsKSQEEKKRIIKKCYENFAFFGLDFI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  81 KLMTMTPENLKRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEWI-TSLPLWMKSDAQLGQIyhpIENKDFDRLFLRSRQ 159
Cdd:PRK08419  84 RNQNTTKEEILNKVTFINEENLLDALKKKRPIIVTTAHYGYWELFsLALAAYYGAVSIVGRL---LKSAPINEMISKRRE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 160 RMGAVCIPMQDTLRRMVEYRRAKQPIviGFISDQkphwvNIHH----WIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRR 235
Cdd:PRK08419 161 QFGIELIDKKGAMKELLKALKQGRAL--GILVDQ-----NVVPkegvEVKFFNKRVTHTTIASILARRYNALIIPVFIFN 233

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 294474363 236 VKRGYYEAEVIPMTR----EPQQLKDYELTDMYFDLLEKSIKRAPEFWLWSHDRWKRTRAE 292
Cdd:PRK08419 234 DDYSHFTITFFPPIRskitDDAEADILEATQAQASACEEMIRKKPDEYFWFHRRFKSFYPE 294
 
Name Accession Description Interval E-value
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 11-286 1.00e-83

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 253.96  E-value: 1.00e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  11 VWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYRIERGFYHFFCDYIVESVKLMTMTPENL 90
Cdd:COG1560    1 LLRLLRLLPLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  91 KRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEWitsLPLWMKS-DAQLGQIYHPIENKDFDRLFLRSRQRMGAVCIPMQ 169
Cdd:COG1560   81 RKRVEVEGLEHLEAALAEGRGVILLTPHFGNWEL---AGAALALrGYPVTAVYRPLKNPLLDRLIRRGRERFGGELIPRK 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 170 DTLRRMVeyRRAKQPIVIGFISDQKPHWVNiHHWIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRRVKRGY-YEAEVIPM 248
Cdd:COG1560  158 DGVRALL--RALRKGGIVGLLPDQDPGRKS-GVFVPFFGVPAATPTGPARLARRTGAPVVPVFARRLPDGRgYRLEIEPP 234

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 294474363 249 TREPQQlKDYELTDMYFDLLEKSIKRAPEFWLWSHDRW 286
Cdd:COG1560  235 LEDFSE-DVEADTQRLNRALEAWIREHPEQWLWLHRRW 271
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 91-287 3.16e-47

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 157.76  E-value: 3.16e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  91 KRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEWitsLPLWM-KSDAQLGQIYHPIENKDFDRLFLRSRQRMGAVCIPMQ 169
Cdd:cd07984    1 LKRVEREGLEHLEAALAKGKGVILLTAHFGNWEL---AGLALaLLGYPVTVVYRPLKNPLLDRLITRGRERFGARLIPRG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 170 DTLRRMVEYRRAKQpiVIGFISDQKPHWvNIHHWIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRRVKRGYYEAEVIPMT 249
Cdd:cd07984   78 GGLRELIRALKKGE--IVGILPDQDPGR-KGGVFVPFFGRPAATPTGPARLALKTGAPVVPAFAYRLPGGGYRIEFEPPL 154

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 294474363 250 REPQQLKDYELTDMYFDLLEKSIKRAPEFWLWSHDRWK 287
Cdd:cd07984  155 ENPPSEDVEEDTQRLNDALEAAIREHPEQWLWFHRRWK 192
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
4-288 2.66e-36

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 132.08  E-value: 2.66e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363    4 LYYIVLAVWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYRIERGFYHFFCDYIVESVKLM 83
Cdd:pfam03279  14 LDWLGIAVLRLLALLPYSALRRIGKGLGRLAGRFLKRRRKIARRNLALCFPEMSEAEREQIIDKSFASVGRAIVETGRVW 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   84 TMTPENLKRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEwitsLP-LWMKSDAQ-LGQIYHPIENKDFDRLFLRSRQRM 161
Cdd:pfam03279  94 FWPDSRIAKRFEVIGLEHIKEALAQGRGAILVGPHFGNWD----LGgRVLGQQYPgMAVYRPNLKNPLLDWLQTSGRERF 169

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  162 GAVCIPMQDTLRRMVeyRRAKQPIVIGFISDQKpHWVNIHHWIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRRVKRG-Y 240
Cdd:pfam03279 170 GGRMLPRQNGIKGLI--KALRKGEVVWYLPDQD-LGRKDSVFVPFFGVPAATTTGPAKLALKTKAAVIPVFPIRNGDGsG 246

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 294474363  241 YEAEVIPMTREPQQLKDYELTDMYFDLLEKSIKRAPEFWLWSHDRWKR 288
Cdd:pfam03279 247 YTVIVHPALDLTITDDVEQIAQAMNQIVEKFIMPAPEQYFWLHRRWKT 294
PRK08419 PRK08419
lipid A biosynthesis lauroyl acyltransferase; Reviewed
 6-292 2.79e-19

lipid A biosynthesis lauroyl acyltransferase; Reviewed


Pssm-ID: 181420 [Multi-domain]  Cd Length: 298  Bit Score: 86.23  E-value: 2.79e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   6 YIVLAVWYVFS----LLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPE-KTDDERYRIERGFYHFFCDYIVESV 80
Cdd:PRK08419   4 RIYLSLFYILKfflaKMPHCIFLRLAKALAFIMRYLDKKRRKIAKANLDFCFGEsKSQEEKKRIIKKCYENFAFFGLDFI 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  81 KLMTMTPENLKRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEWI-TSLPLWMKSDAQLGQIyhpIENKDFDRLFLRSRQ 159
Cdd:PRK08419  84 RNQNTTKEEILNKVTFINEENLLDALKKKRPIIVTTAHYGYWELFsLALAAYYGAVSIVGRL---LKSAPINEMISKRRE 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 160 RMGAVCIPMQDTLRRMVEYRRAKQPIviGFISDQkphwvNIHH----WIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRR 235
Cdd:PRK08419 161 QFGIELIDKKGAMKELLKALKQGRAL--GILVDQ-----NVVPkegvEVKFFNKRVTHTTIASILARRYNALIIPVFIFN 233

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 294474363 236 VKRGYYEAEVIPMTR----EPQQLKDYELTDMYFDLLEKSIKRAPEFWLWSHDRWKRTRAE 292
Cdd:PRK08419 234 DDYSHFTITFFPPIRskitDDAEADILEATQAQASACEEMIRKKPDEYFWFHRRFKSFYPE 294
PRK08706 PRK08706
lipid A biosynthesis lauroyl acyltransferase; Provisional
 7-297 4.30e-16

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 169557 [Multi-domain]  Cd Length: 289  Bit Score: 77.21  E-value: 4.30e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   7 IVLAVWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYRIERGFYHFFCDYIVESVKLMTMT 86
Cdd:PRK08706   3 FIFFVLYVLQFLPFALLHKLADLTGLLAYLLVKPRRRIGEINLAKCFPEWDEEKRKTVLKQHFKHMAKLMLEYGLYWYAP 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  87 PENLKRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEWITslpLWMKSDAQLGQIYHPIENKDFDRLFLRSRQRMG-AVC 165
Cdd:PRK08706  83 AGRLKSLVRYRNKHYLDDALAAGEKVIILYPHFTAFEMAV---YALNQDVPLISMYSHQKNKILDEQILKGRNRYHnVFL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 166 IPMQDTLRRMVE-YRRAKQPIVigFISDQKpHWVNIHHWIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRRVKRGYYEAE 244
Cdd:PRK08706 160 IGRTEGLRALVKqFRKSSAPFL--YLPDQD-FGRNDSVFVDFFGIQTATITGLSRIAALANAKVIPAIPVREADNTVTLH 236

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 294474363 245 VIPmtrepqQLKDYELTDMYFD------LLEKSIKRAPEFWLWSHDRWKrTRAEFNERF 297
Cdd:PRK08706 237 FYP------AWDSFPSEDAQADaqrmnrFIEERVREHPEQYFWLHKRFK-TRPEGSPDF 288
PRK06946 PRK06946
lipid A biosynthesis lauroyl acyltransferase; Provisional
 6-287 5.86e-14

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 180770 [Multi-domain]  Cd Length: 293  Bit Score: 70.87  E-value: 5.86e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   6 YIVLAVWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYRIERG-FYHFFCDYIVESVKlMT 84
Cdd:PRK06946   7 ALAIGLLKLLAFLPYGLTARFGDGLGWLLYRIPSRRRRIVHTNLKLCFPDWSDARREELARRhFRHVIRSYVERSVQ-WF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  85 MTPENLKRrmvfkgVEQIDEAIN----SGQScAVYLG-HLCNWEwITSLPLWMKSDAQLGQIYHPIENKDFDRLFLRSRQ 159
Cdd:PRK06946  86 GSEKKLEK------LVQVDSAIDltdpDGPP-TIFLGlHFVGIE-AGSIWLNYSLRRRVGSLYTPMSNPLLDAIAKAARG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 160 RMGAVCIPMQDTLRRMVEYRRAKQPIVIGFISDqkpHWVNIHHWIDFLHHDTPVLTGTERIAKKMNYAV--FFMDVRRVK 237
Cdd:PRK06946 158 RFGAEMVSRADSARQVLRWLRDGKPVMLGADMD---FGLRDSTFVPFFGVPACTLTAVSRLARTGGAQVvpFITEVLPDY 234

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 294474363 238 RGyYEAEVIPmtrepqQLKDYELTDMYFD------LLEKSIKRAPEFWLWSHDRWK 287
Cdd:PRK06946 235 KG-YRLRVFK------PWENYPTGDDDLDarrmnaFLEEQIRLMPEQYYWVHKRFK 283
PRK06628 PRK06628
lipid A biosynthesis lauroyl acyltransferase; Provisional
 36-288 6.56e-12

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 102471  Cd Length: 290  Bit Score: 64.95  E-value: 6.56e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  36 GVLGYRKKVIRRNIKESFPEKTDDERyrIERGFYHFFCDYIVESVKLMTMTPENLKRRMVFKGVEQIDEAinSGQSCAVY 115
Cdd:PRK06628  44 GILFAVNKIARRNIKAVFGDMCDVEK--IIDQTWDNFGRFIGEFTYVNKMDEAELERRIEIIGIENIKKL--EGQPFLLF 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 116 LGHLCNWEwiTSLPLWMKSDAQLGQIYHPIENKDFDRLFLRSRQRMGAVCIPMQDTLRRMVeYRRAKQPIVIGFISDQKp 195
Cdd:PRK06628 120 SGHFANWD--ISLKILHKFYPKVAVIYRKANNPYVNKLVNESRAGDKLRLIPKGPEGSRAL-VRAIKESESIVMLVDQK- 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 196 hwVNIHHWIDFLHHDTPVLTGTERIAKKMNYAVFFMDVRRVKRGYYEAEVIPMTREPQ----QLKDYELTDMYFDLLEKS 271
Cdd:PRK06628 196 --MNDGIEVPFLGHPAMTASAIAKIALQYKYPIIPCQIIRTKGSYFKVIVHPQLKFEQtgdnKADCYNIMLNINQMLGEW 273

                        250
                 ....*....|....*..
gi 294474363 272 IKRAPEFWLWSHDRWKR 288
Cdd:PRK06628 274 VKQNPAQWFWFHNRWKK 290
PRK05646 PRK05646
lipid A biosynthesis lauroyl acyltransferase; Provisional
 6-296 1.15e-10

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235543 [Multi-domain]  Cd Length: 310  Bit Score: 61.37  E-value: 1.15e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   6 YIVLAVWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYRIERGfyHFFCDYIveSVKLMTM 85
Cdd:PRK05646  19 WLGLGLLWLVVQLPYRVLLWLGRALGALMYRLAGSRRRIAARNLELCFPEKSAAERERLLKE--NFASTGI--AFFEMAM 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  86 T----PENLKRRMVFKGVEQIDEAINSGQSCAVYLGHLcnwewiTSLPLwmkSDAQLGQ------IYHPIENKDFDRLFL 155
Cdd:PRK05646  95 SwwwpKARLARLAHIEGLEHLQQAQQEGQGVILMALHF------TTLEI---GAALLGQqhtidgMYREHKNPVFDFIQR 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 156 RSRQR--MGAVCIPMQDtLRRMVEYRRAKQpiVIGFISDQKpHWVNIHHWIDFLHHDTPVLTGTERIAKKMNYAVF-FMD 232
Cdd:PRK05646 166 RGRERhnLDSTAIERED-VRGMLKLLRAGR--AIWYAPDQD-YGAKQSIFVPLFGIPAATVTATTKFARLGRARVIpFTQ 241

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 233 VRRVKRGYYEAEVIPmtrepqQLKDYELTDMYFDLL------EKSIKRAPEFWLWSHDRWKrTRAEFNER 296
Cdd:PRK05646 242 KRLADGSGYRLVIHP------PLEDFPGESEEADCLrinqwvERVVRECPEQYLWAHRRFK-SRPEGEPK 304
PRK05906 PRK05906
lipid A biosynthesis lauroyl acyltransferase; Provisional
 4-288 9.34e-10

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 168292 [Multi-domain]  Cd Length: 454  Bit Score: 59.41  E-value: 9.34e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   4 LYYIVLAVWYVFSLLPLR-VHYFISDLLFWLLYGVLGYRKKVIRrNIKESFPEKTDDERYRIERgfyHFFCDYIVESVKL 82
Cdd:PRK05906  17 VYYLGLGVITILRLLPRSsLRLFGKGLGTLLFYFISDYRKTALT-NLALAFPEKSFAERYQIAR---QSVQHVIITFLEL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  83 MTM------------------TPENLKRRMVF--KGVEQIDEAINSGQSCAVYLGHLCNWEwitsLP-LWMKSDAQLGQI 141
Cdd:PRK05906  93 LAVeklaghideliaiatsedAPEGFFPEEVSsqQELEHTFSRLDEQEGAILFCGHQANWE----LPfLYITKRYPGLAF 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 142 YHPIENKDFDRLFLRSRQRMGAVCIPMQDTLRRMVeyRRAKQPIVIGFISDQKphWVNIHHWIDFLHHDTPVLTGTERIA 221
Cdd:PRK05906 169 AKPIKNRRLNKKIFSLRESFKGKIVPPKNGINQAL--RALHQGEVVGIVGDQA--LLSSSYSYPLFGSQAFTTTSPALLA 244

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 294474363 222 KKMNYAVFFMDVRRVKRGY--------YEAEVIPMTREPQQLKDyelTDMYFdlLEKSIKRAPEFWLWSHDRWKR 288
Cdd:PRK05906 245 YKTGKPVIAVAIYRKPNGYlvvpskkfYANKSLPIKESTEQLMD---RLMRF--LEKGIACKPEQWMWLHKRWKR 314
PRK08734 PRK08734
lauroyl acyltransferase;
26-195 3.92e-09

lauroyl acyltransferase;


Pssm-ID: 181543 [Multi-domain]  Cd Length: 305  Bit Score: 56.81  E-value: 3.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  26 ISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYRIERGFYHFFCDYIVESVKLMTMTP-ENLKRRMVFKGVEQIDE 104
Cdd:PRK08734  28 LADLLAWSWRKLNARESRVTRRNLELAYPELSPQQRAQLHAQILRSTARQALEVLRTWTHPPaENLARLRQRHGQELYDA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 105 AINSGQSCAVYLGHLCNWEWITSlplWMKSDAQLGQIYHPIENKDFDRLFLRSRQRMGAVCIPMQDTLRRMVeYRRAKQP 184
Cdd:PRK08734 108 ALASGRGVIVAAPHFGNWELLNQ---WLSERGPIAIVYRPPESEAVDGFLQLVRGGDNVRQVRAEGPAVRQL-FKVLKDG 183

                        170
                 ....*....|.
gi 294474363 185 IVIGFISDQKP 195
Cdd:PRK08734 184 GAVGILPDQQP 194
PRK06553 PRK06553
lipid A biosynthesis lauroyl acyltransferase; Provisional
 41-286 8.16e-08

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235827 [Multi-domain]  Cd Length: 308  Bit Score: 52.67  E-value: 8.16e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  41 RKKVIRRNIKESFPEKTDDERYRIERGFY----HFFCDYIVESvKLMTMTPENLKR-RMVFKGVEQIDEAINSGQSCAVY 115
Cdd:PRK06553  60 RHRVALDNLRAAFPEKSEAEIEAIALGMWdnlgRLGAEYAFLD-AIFDYDPEAPEPgRVEVRGIEIFERLRDDGKPALIF 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 116 LGHLCNWEWitsLPLWMKS-DAQLGQIYHPIENKDFDRLFLRSRQ-RMGAVcIPMQDT----LRRMVEyrRAKQpivIGF 189
Cdd:PRK06553 139 TAHLGNWEL---LAIAAAAfGLDVTVLFRPPNNPYAARKVLEARRtTMGGL-VPSGAGaafaLAGVLE--RGGH---VGM 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 190 ISDQkpHWVNiHHWIDFLHHDT---PVLTgteRIAKKMNYAVFFMDVRRVKRGYYEAEV---IPMTREPQQLKDYELT-D 262
Cdd:PRK06553 210 LVDQ--KFTR-GVEVTFFGRPVktnPLLA---KLARQYDCPVHGARCIRLPGGRFRLELterVELPRDADGQIDVQATmQ 283

                        250       260
                 ....*....|....*....|....
gi 294474363 263 MYFDLLEKSIKRAPEFWLWSHDRW 286
Cdd:PRK06553 284 ALTDVVEGWVREYPGQWLWLHRRW 307
PRK05645 PRK05645
lysophospholipid acyltransferase;
7-195 1.20e-05

lysophospholipid acyltransferase;


Pssm-ID: 135493 [Multi-domain]  Cd Length: 295  Bit Score: 46.05  E-value: 1.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   7 IVLAVWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYR--------IERGFYHFFCDYIVE 78
Cdd:PRK05645   8 LMVGALRLFALLPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSPAELEKlvgqslmdIGKTLTESACAWIWP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  79 SVKLMTMTPEnlkrrmvFKGVEQIDEAINSGQSCAVYLGHLCNWEwitSLPLWMKSDAQLGQIYHPIENKDFDRLFLRSR 158
Cdd:PRK05645  88 PQKSLELVRE-------VEGLEVLEQALASGKGVVGITSHLGNWE---VLNHFYCSQCKPIIFYRPPKLKAVDELLRKQR 157

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 294474363 159 QRMGAVCIPM--QDTLRRMVEYRRAKQpivIGFISDQKP 195
Cdd:PRK05645 158 VQLGNRVAPStkEGILSVIKEVRKGGQ---VGIPADPEP 193
PRK06860 PRK06860
lipid A biosynthesis lauroyl acyltransferase; Provisional
 9-292 1.78e-05

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235880 [Multi-domain]  Cd Length: 309  Bit Score: 45.67  E-value: 1.78e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   9 LAVWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYR-------------IERGFYHFFCDY 75
Cdd:PRK06860  25 IGLLWLIVLLPYPVLYKLGRGLGKLALRFMKRRAKIARRNLELCFPEMSEQEREAivvknfesvgmalIETGMAWFWPDW 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  76 IVesvklmtmtpenlKRRMVFKGVEQIDEAINSGQSCAVYLGHLCNWEwitslpLWMKSDAQLGQ---IYHPIENKDFDR 152
Cdd:PRK06860 105 RI-------------KRWTEVEGLEHIREVQAQGRGVLLVGVHFLTLE------LGARIFGMHNPgigVYRPNDNPLYDW 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363 153 LFLRSRQRMGAVCIPMQDtLRRMVeyRRAKQPIVIGFISD-----QKPHWVNIhhwidFLHHDTPVLTGTERIAKKMNYA 227
Cdd:PRK06860 166 LQTWGRLRSNKSMLDRKD-LKGMI--KALKKGERIWYAPDhdygpRSSVFVPF-----FAVEQAATTTGTWMLARMSKAA 237

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 294474363 228 VF-FMDVRRVKRGYYEAEVIPMTREPqQLKDYELTDMYFD-LLEKSIKRAPEFWLWSHDRWKrTRAE 292
Cdd:PRK06860 238 VIpFVPRRKPDGKGYELIILPPEDSP-PLDDAEATAAWMNkVVEKCILMAPEQYMWLHRRFK-TRPE 302
PRK08943 PRK08943
lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated
 14-163 1.31e-04

lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated


Pssm-ID: 236355  Cd Length: 314  Bit Score: 42.93  E-value: 1.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363  14 VFSLLPLRVHYFISDLLFWLlygVLGYRKKVIRR---NIKESFPEKTDDERYRIERGFYHFFCDYIVESVKLMTMTPENL 90
Cdd:PRK08943  35 GLALMPPRLRDPLAAKLGRL---VGKLAKKARRRariNLSLCFPEKSEAEREAIIDEMFATAPQAMLMMAELALRSPKHL 111

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 294474363  91 KRRMVFKGVEQIDEAINSGQSCAVYLGHLcnweWITSLP-LWMKSDAQ-LGQIYHPIENKDFDRLFLRSRQRMGA 163
Cdd:PRK08943 112 QRRVEWHGLEILEEARANGENVIFLVPHG----WAIDIPaMLLASQGQpMAAMFHNQRNPLFDWLWNRVRRRFGG 182
PRK07920 PRK07920
lipid A biosynthesis lauroyl acyltransferase; Provisional
 9-123 6.35e-03

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 236131 [Multi-domain]  Cd Length: 298  Bit Score: 37.60  E-value: 6.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 294474363   9 LAVWYVFSLLPLRVHYFISDLLFWLLYGVLGYRKKVIRRNIKESFPEKTDDERYRIERGFYHFFCDYIVESVKLMTMTPE 88
Cdd:PRK07920   5 AAGWRLVRALPEPVARRLFDAGADVAWRRRGGGVRQLRRNLARVVPDAPAAVLDALVRAAMRSYARYWREAFRLPSMSRE 84

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 294474363  89 NLKRRM--VFKGVEQIDEAINSGQSCAVYLGHLCNWE 123
Cdd:PRK07920  85 RLAARVrvSIEGLEHLDAALAAGRGVVLALPHSGNWD 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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