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Conserved domains on  [gi|289517861|gb|ADD00718|]
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ataxin 3 variant ref [Homo sapiens]

Protein Classification

Josephin domain-containing protein( domain architecture ID 10489273)

Josephin domain-containing protein similar to human Josephin-1 that may act as a deubiquitinating enzyme

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Josephin pfam02099
Josephin;
9-151 8.57e-79

Josephin;


:

Pssm-ID: 460444  Cd Length: 154  Bit Score: 230.19  E-value: 8.57e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289517861    9 QEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERMRMAEGGvtSEDYRTFLQQ-PSGNMDDSGFFSIQVISNALKVW 87
Cdd:pfam02099   1 QELQLCAQHALNNLLQGPYFTAVDLADIARQLDEEERSLMAEGP--SADYWTFLSFgSSHNVDDSGNFSIQVLEKALEVW 78
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 289517861   88 GLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALF 151
Cdd:pfam02099  79 GLELVPWRSPEMQDAKDDPETEVGFICNLSQHWFTIRKFGGQWYNLNSLLKAPELISDTYLSAF 142
 
Name Accession Description Interval E-value
Josephin pfam02099
Josephin;
9-151 8.57e-79

Josephin;


Pssm-ID: 460444  Cd Length: 154  Bit Score: 230.19  E-value: 8.57e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289517861    9 QEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERMRMAEGGvtSEDYRTFLQQ-PSGNMDDSGFFSIQVISNALKVW 87
Cdd:pfam02099   1 QELQLCAQHALNNLLQGPYFTAVDLADIARQLDEEERSLMAEGP--SADYWTFLSFgSSHNVDDSGNFSIQVLEKALEVW 78
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 289517861   88 GLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALF 151
Cdd:pfam02099  79 GLELVPWRSPEMQDAKDDPETEVGFICNLSQHWFTIRKFGGQWYNLNSLLKAPELISDTYLSAF 142
 
Name Accession Description Interval E-value
Josephin pfam02099
Josephin;
9-151 8.57e-79

Josephin;


Pssm-ID: 460444  Cd Length: 154  Bit Score: 230.19  E-value: 8.57e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 289517861    9 QEGSLCAQHCLNNLLQGEYFSPVELSSIAHQLDEEERMRMAEGGvtSEDYRTFLQQ-PSGNMDDSGFFSIQVISNALKVW 87
Cdd:pfam02099   1 QELQLCAQHALNNLLQGPYFTAVDLADIARQLDEEERSLMAEGP--SADYWTFLSFgSSHNVDDSGNFSIQVLEKALEVW 78
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 289517861   88 GLELILFNSPEYQRLRIDPINERSFICNYKEHWFTVRKLGKQWFNLNSLLTGPELISDTYLALF 151
Cdd:pfam02099  79 GLELVPWRSPEMQDAKDDPETEVGFICNLSQHWFTIRKFGGQWYNLNSLLKAPELISDTYLSAF 142
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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