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Conserved domains on  [gi|28948963]
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Chain A, Nucleoplasmin-like protein

Protein Classification

nucleoplasmin-like domain-containing protein( domain architecture ID 10503565)

nucleoplasmin-like domain-containing protein similar to Homo sapiens nucleoplasmin-2 and nucleoplasmin-3

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Nucleoplasmin pfam03066
Nucleoplasmin/nucleophosmin domain; Nucleoplasmins are also known as chromatin decondensation ...
 6-105 4.10e-42

Nucleoplasmin/nucleophosmin domain; Nucleoplasmins are also known as chromatin decondensation proteins. They bind to core histones and transfer DNA to them in a reaction that requires ATP. This is thought to play a role in the assembly of regular nucleosomal arrays.


:

Pssm-ID: 460792  Cd Length: 102  Bit Score: 133.54  E-value: 4.10e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28948963     6 FYGVTLTAESDSVTWDVDEDYARGQKLVIKQILLGAEAKEnEFNVVEVNTP---KDSVQIPIAVLKAGETRAVNPDVEFY 82
Cdd:pfam03066   1 LWGCELKKEKKTVTFDVEEDEDCEHQLSLKTICLGAKAKD-ELNVVEVEAMnykKKPIKVPIASLKVSVLPMVSLDGLEP 79

                          90       100
                  ....*....|....*....|...
gi 28948963    83 ESKVTFKLIKGSGPVYIHGHNIK 105
Cdd:pfam03066  80 TPPVTFRLKSGSGPVHISGQHLV 102
 
Name Accession Description Interval E-value
Nucleoplasmin pfam03066
Nucleoplasmin/nucleophosmin domain; Nucleoplasmins are also known as chromatin decondensation ...
 6-105 4.10e-42

Nucleoplasmin/nucleophosmin domain; Nucleoplasmins are also known as chromatin decondensation proteins. They bind to core histones and transfer DNA to them in a reaction that requires ATP. This is thought to play a role in the assembly of regular nucleosomal arrays.


Pssm-ID: 460792  Cd Length: 102  Bit Score: 133.54  E-value: 4.10e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28948963     6 FYGVTLTAESDSVTWDVDEDYARGQKLVIKQILLGAEAKEnEFNVVEVNTP---KDSVQIPIAVLKAGETRAVNPDVEFY 82
Cdd:pfam03066   1 LWGCELKKEKKTVTFDVEEDEDCEHQLSLKTICLGAKAKD-ELNVVEVEAMnykKKPIKVPIASLKVSVLPMVSLDGLEP 79

                          90       100
                  ....*....|....*....|...
gi 28948963    83 ESKVTFKLIKGSGPVYIHGHNIK 105
Cdd:pfam03066  80 TPPVTFRLKSGSGPVHISGQHLV 102
 
Name Accession Description Interval E-value
Nucleoplasmin pfam03066
Nucleoplasmin/nucleophosmin domain; Nucleoplasmins are also known as chromatin decondensation ...
 6-105 4.10e-42

Nucleoplasmin/nucleophosmin domain; Nucleoplasmins are also known as chromatin decondensation proteins. They bind to core histones and transfer DNA to them in a reaction that requires ATP. This is thought to play a role in the assembly of regular nucleosomal arrays.


Pssm-ID: 460792  Cd Length: 102  Bit Score: 133.54  E-value: 4.10e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28948963     6 FYGVTLTAESDSVTWDVDEDYARGQKLVIKQILLGAEAKEnEFNVVEVNTP---KDSVQIPIAVLKAGETRAVNPDVEFY 82
Cdd:pfam03066   1 LWGCELKKEKKTVTFDVEEDEDCEHQLSLKTICLGAKAKD-ELNVVEVEAMnykKKPIKVPIASLKVSVLPMVSLDGLEP 79

                          90       100
                  ....*....|....*....|...
gi 28948963    83 ESKVTFKLIKGSGPVYIHGHNIK 105
Cdd:pfam03066  80 TPPVTFRLKSGSGPVHISGQHLV 102
NPL pfam17800
Nucleoplasmin-like domain;
6-104 6.08e-12

Nucleoplasmin-like domain;


Pssm-ID: 465511  Cd Length: 90  Bit Score: 56.46  E-value: 6.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28948963     6 FYGVTLTAeSDSVTWDVDEDyargqkLVIKQILLGAEAKENefNVVEVNTPKDSVQIPIAVLKAGETRAVNPDVEFYES- 84
Cdd:pfam17800   1 FWGLEVPP-GKPVTLEVPED------LHITNAALGPSAKPE--TVVKVKVDDEEEEFVLCTLTPGKVEQQPLDLVFSEGe 71

                          90       100
                  ....*....|....*....|
gi 28948963    85 KVTFKlIKGSGPVYIHGHNI 104
Cdd:pfam17800  72 EVTFS-VKGKNTVHLTGYYI 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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