NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|28603830|ref|NP_776155|]
View 

FUN14 domain-containing protein 1 [Homo sapiens]

Protein Classification

FUN14 domain-containing protein( domain architecture ID 10522754)

FUN14 domain-containing protein similar to Homo sapiens FUN14 domain-containing protein 1 that acts as an activator of hypoxia-induced mitophagy, an important mechanism for mitochondrial quality control

Gene Ontology:  GO:0005741

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FUN14 pfam04930
FUN14 family; This family of short proteins are found in eukaryotes and some archaea. Although ...
 54-153 1.93e-36

FUN14 family; This family of short proteins are found in eukaryotes and some archaea. Although the function of these proteins is not known they may contain transmembrane helices.


:

Pssm-ID: 461487  Cd Length: 95  Bit Score: 120.79  E-value: 1.93e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603830    54 IVMGGVTGWCAGFLFQKVGKLAATAVGGGFLLLQIASHSGYVQIDWKRVEKDVNKAKRQIKKRANKAAPEInnlieEATE 133
Cdd:pfam04930   1 LGFGGVLGLCAGYALKKVGKLAAVAVGGGFLLLQYLAYQGYITVNWDKVEKDVESALDRNGDGKIDTKDAK-----VLLD 75

                          90       100
                  ....*....|....*....|
gi 28603830   134 FIKQNIVISSGFVGGFLLGL 153
Cdd:pfam04930  76 FLTANLPFSAGFLAGFLLGL 95
 
Name Accession Description Interval E-value
FUN14 pfam04930
FUN14 family; This family of short proteins are found in eukaryotes and some archaea. Although ...
 54-153 1.93e-36

FUN14 family; This family of short proteins are found in eukaryotes and some archaea. Although the function of these proteins is not known they may contain transmembrane helices.


Pssm-ID: 461487  Cd Length: 95  Bit Score: 120.79  E-value: 1.93e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603830    54 IVMGGVTGWCAGFLFQKVGKLAATAVGGGFLLLQIASHSGYVQIDWKRVEKDVNKAKRQIKKRANKAAPEInnlieEATE 133
Cdd:pfam04930   1 LGFGGVLGLCAGYALKKVGKLAAVAVGGGFLLLQYLAYQGYITVNWDKVEKDVESALDRNGDGKIDTKDAK-----VLLD 75

                          90       100
                  ....*....|....*....|
gi 28603830   134 FIKQNIVISSGFVGGFLLGL 153
Cdd:pfam04930  76 FLTANLPFSAGFLAGFLLGL 95
 
Name Accession Description Interval E-value
FUN14 pfam04930
FUN14 family; This family of short proteins are found in eukaryotes and some archaea. Although ...
 54-153 1.93e-36

FUN14 family; This family of short proteins are found in eukaryotes and some archaea. Although the function of these proteins is not known they may contain transmembrane helices.


Pssm-ID: 461487  Cd Length: 95  Bit Score: 120.79  E-value: 1.93e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603830    54 IVMGGVTGWCAGFLFQKVGKLAATAVGGGFLLLQIASHSGYVQIDWKRVEKDVNKAKRQIKKRANKAAPEInnlieEATE 133
Cdd:pfam04930   1 LGFGGVLGLCAGYALKKVGKLAAVAVGGGFLLLQYLAYQGYITVNWDKVEKDVESALDRNGDGKIDTKDAK-----VLLD 75

                          90       100
                  ....*....|....*....|
gi 28603830   134 FIKQNIVISSGFVGGFLLGL 153
Cdd:pfam04930  76 FLTANLPFSAGFLAGFLLGL 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH