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Conserved domains on  [gi|28603666|ref|NP_789759|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Excalfactoria chinensis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 7.68e-48

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 152.98  E-value: 7.68e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666    1 MTYFVIFLGVCFMLGTLAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666   81 AWGSWRVVVYGLG-FVLVVCVGVVLGGFVDFWKVGVVTVDSGGVSFVRFDFSGVAVFYSCGVGLFLVAGWGLLLVLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 28603666  160 ELVRGLSRGAIRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 7.68e-48

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 152.98  E-value: 7.68e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666    1 MTYFVIFLGVCFMLGTLAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666   81 AWGSWRVVVYGLG-FVLVVCVGVVLGGFVDFWKVGVVTVDSGGVSFVRFDFSGVAVFYSCGVGLFLVAGWGLLLVLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 28603666  160 ELVRGLSRGAIRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-92 4.80e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 49.42  E-value: 4.80e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28603666    17 LAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSL-AADPYPEAWGSWRVVVYGL 92
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALL 77
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 7.68e-48

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 152.98  E-value: 7.68e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666    1 MTYFVIFLGVCFMLGTLAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666   81 AWGSWRVVVYGLG-FVLVVCVGVVLGGFVDFWKVGVVTVDSGGVSFVRFDFSGVAVFYSCGVGLFLVAGWGLLLVLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 28603666  160 ELVRGLSRGAIRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.01e-44

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 145.28  E-value: 1.01e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666    1 MTYFVIFLGVCFMLGTLAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666   81 AWGSWRVVVYGLGFVLVVCVGVVLGGFVDFWKVGVVTVDSGGVSFVRFDFSGVAVFYSCGVGLFLVAGWGLLLVLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 28603666  161 LVRGLSRGAIRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 1.22e-42

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 139.98  E-value: 1.22e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666    1 MTYFVIFLGVCFMLGTLAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666   81 AWGSWRVVVYGLGFVLVVCVGVVLGGFVDFwKVGVVTVDSGGVSFVRFDFSGVAVFYSCGVGLFLVAGWGLLLVLFVVLE 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFS-LEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                        170
                 ....*....|...
gi 28603666  161 LVRGLSRGAIRAV 173
Cdd:MTH00065 160 VTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-149 1.60e-27

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 101.42  E-value: 1.60e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666    1 MTYFVIFLGVCFMLGTLAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 28603666   81 AWGSwRVVVYGLGFVLVVCVGVVLGGFVDFWKVGVVTV----------DSGGVSFVRFDFSGVAVFYSCGVGLFLVAGW 149
Cdd:MTH00109  82 TWVS-NKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNfnglgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGW 159
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 4.42e-20

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 81.96  E-value: 4.42e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666    1 MTYFVIFLGVCFMLGTLAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666   81 AWGSWRVVVYGLGFVLVVCVGVVLGGFVDFWKVGVvtvdsGGVSFVRFDFSGVAVFYSCGVGLFLVAGWGLLLVLFVVLE 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWM-----GVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 28603666  161 LVRGLSRGAIRAV 173
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 5-79 3.60e-12

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 61.07  E-value: 3.60e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 28603666    5 VIFLGVCFML-GTLAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSLAADPYP 79
Cdd:MTH00045   2 VFYLFLILMLfGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP 77
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-92 4.80e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 49.42  E-value: 4.80e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28603666    17 LAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSL-AADPYPEAWGSWRVVVYGL 92
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALL 77
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 49-74 5.16e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 38.63  E-value: 5.16e-04
                         10        20
                 ....*....|....*....|....*.
gi 28603666   49 SFISLVLFMIYLGGMLVVFVYSVSLA 74
Cdd:MTH00166  46 FWFSYILFLIFLGGMLVLFIYITSLA 71
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-73 4.13e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 36.24  E-value: 4.13e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 28603666    7 FLGVCFMLGTLAVASNPSPYYGVVGLVLASVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSL 73
Cdd:MTH00021   1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 5-74 7.50e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 35.25  E-value: 7.50e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 28603666    5 VIFLGVCFMLGTLAVASNPSPYYGVVGLVLaSVVGCGWLVNLGVSFISLVLFMIYLGGMLVVFVYSVSLA 74
Cdd:MTH00152   4 MILLSVCFSLFLLLPLSKQPLSLGLVLLLL-SLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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