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Conserved domains on  [gi|283133749|dbj|BAI64514|]
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DNA segregation ATPase FtsK/SpoIIIE [Rothia mucilaginosa DY-18]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
T7SS_EccC_a super family cl37347
type VII secretion protein EccCa; This model represents the N-terminal domain or EccCa subunit ...
 601-913 1.29e-46

type VII secretion protein EccCa; This model represents the N-terminal domain or EccCa subunit of the type VII secretion protein EccC as found in the Actinobacteria. Type VII secretion is defined more broadly as including secretion systems for ESAT-6-like proteins in the Firmicutes as well as in the Actinobacteria, but this family does not show close homologs in the Firmicutes. [Protein fate, Protein and peptide secretion and trafficking]


The actual alignment was detected with superfamily member TIGR03924:

Pssm-ID: 274858 [Multi-domain]  Cd Length: 658  Bit Score: 179.40  E-value: 1.29e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   601 LCQHADGLSL---EAFCAALENlYRAGCEQEQGALSEGQvhqsahlfSSLQQQNRADDMAVESVLQRWSAQRYASDIRCY 677
Cdd:TIGR03924  342 FGVAPDQLSIaeaEALARRLAR-WRAATAGTVDAPLTGA--------RDLLELLGIGDPATLDVDRLWRPRPGRDRLRVP 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   678 LGVSSGGS---LNIGLSEH---GPHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFKGSAGLGPLAQLPHALS 751
Cdd:TIGR03924  413 IGVGDDGEpveLDLKESAEggmGPHGLCIGATGSGKSELLRTLVLGLAATHSPEQLNLVLVDFKGGATFLGLEGLPHVSA 492

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   752 VLSNF--DVSAVERALEFLRADIHRREVDLQALG-VNSYRDYLASCQAAGTTPRYPELLIVVDEFRMLIDSMPDaMAELM 828
Cdd:TIGR03924  493 VITNLadEAPLVDRMQDALAGEMNRRQELLRAAGnFANVAEYEKARAAGADLPPLPALFVVVDEFSELLSQHPD-FADLF 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   829 -RIATIGRSLGLHLVLATQRPQGAISQDIRANIATSICLRVASAQDSYNLLEHESAAYISaAHPGAGYVRLPDGRSLPFR 907
Cdd:TIGR03924  572 vAIGRLGRSLGVHLLLASQRLDEGRLRGLESHLSYRIGLKTFSASESRAVLGVPDAYHLP-STPGAGYLKVDTAEPVRFR 650


                   ....*.
gi 283133749   908 APLVDA 913
Cdd:TIGR03924  651 AAYVSG 656
Yop-YscD_cpl super family cl48305
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain ...
 124-199 3.80e-03

Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain of Yop proteins like YscD from Proteobacteria. YscD forms part of the inner membrane component of the bacterial type III secretion injectosome apparatus.


The actual alignment was detected with superfamily member pfam16697:

Pssm-ID: 465238 [Multi-domain]  Cd Length: 94  Bit Score: 38.01  E-value: 3.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   124 ILRGPEAGATFPISRGRTSLGRAALparggeqpHHIHLQDPFLKPVHGSFYADSSGIR----------WIEKRPAASEGS 193
Cdd:pfam16697    2 VLSGPHAGAEFPLEGGRYRIGSDPD--------CDIVLSDKEVSRVHLKLEVDDEGWRlddlgsgngtLVNGQRVTELGI 73


                   ....*.
gi 283133749   194 EKAHGS 199
Cdd:pfam16697   74 ALRPGD 79
 
Name Accession Description Interval E-value
T7SS_EccC_a TIGR03924
type VII secretion protein EccCa; This model represents the N-terminal domain or EccCa subunit ...
 601-913 1.29e-46

type VII secretion protein EccCa; This model represents the N-terminal domain or EccCa subunit of the type VII secretion protein EccC as found in the Actinobacteria. Type VII secretion is defined more broadly as including secretion systems for ESAT-6-like proteins in the Firmicutes as well as in the Actinobacteria, but this family does not show close homologs in the Firmicutes. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274858 [Multi-domain]  Cd Length: 658  Bit Score: 179.40  E-value: 1.29e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   601 LCQHADGLSL---EAFCAALENlYRAGCEQEQGALSEGQvhqsahlfSSLQQQNRADDMAVESVLQRWSAQRYASDIRCY 677
Cdd:TIGR03924  342 FGVAPDQLSIaeaEALARRLAR-WRAATAGTVDAPLTGA--------RDLLELLGIGDPATLDVDRLWRPRPGRDRLRVP 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   678 LGVSSGGS---LNIGLSEH---GPHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFKGSAGLGPLAQLPHALS 751
Cdd:TIGR03924  413 IGVGDDGEpveLDLKESAEggmGPHGLCIGATGSGKSELLRTLVLGLAATHSPEQLNLVLVDFKGGATFLGLEGLPHVSA 492

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   752 VLSNF--DVSAVERALEFLRADIHRREVDLQALG-VNSYRDYLASCQAAGTTPRYPELLIVVDEFRMLIDSMPDaMAELM 828
Cdd:TIGR03924  493 VITNLadEAPLVDRMQDALAGEMNRRQELLRAAGnFANVAEYEKARAAGADLPPLPALFVVVDEFSELLSQHPD-FADLF 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   829 -RIATIGRSLGLHLVLATQRPQGAISQDIRANIATSICLRVASAQDSYNLLEHESAAYISaAHPGAGYVRLPDGRSLPFR 907
Cdd:TIGR03924  572 vAIGRLGRSLGVHLLLASQRLDEGRLRGLESHLSYRIGLKTFSASESRAVLGVPDAYHLP-STPGAGYLKVDTAEPVRFR 650


                   ....*.
gi 283133749   908 APLVDA 913
Cdd:TIGR03924  651 AAYVSG 656
FtsK_SpoIIIE pfam01580
FtsK/SpoIIIE family; FtsK has extensive sequence similarity to wide variety of proteins from ...
 690-849 3.69e-22

FtsK/SpoIIIE family; FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids, termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif. It is found in the FtsK cell division protein from E. coli and the stage III sporulation protein E SpoIIIE, which has roles in regulation of prespore specific gene expression in B. subtilis. A mutation in FtsK causes a temperature sensitive block in cell division and it is involved in peptidoglycan synthesis or modification. The SpoIIIE protein is implicated in intercellular chromosomal DNA transfer.


Pssm-ID: 279863 [Multi-domain]  Cd Length: 219  Bit Score: 96.68  E-value: 3.69e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   690 LSEHGPHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFKGSAgLGPLAQLPHALSVLSNFDVSAVERALEFLR 769
Cdd:pfam01580   34 LKKMPVHLLIAGATGSGKSVALNTLILSLAYMHTPEEVQLYCIDPKMGE-LSAYEDIPHLLSVPVATDPKRALRALEWLV 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   770 ADIHRREVDLQALGVNSYRDY----------------------LASCQAAGTTPRYPELLIVVDEFrmlIDSMPDAMAE- 826
Cdd:pfam01580  113 DEMERRYALFRALGVRSIAGYngeiaedpldgfgdvflviygvHVMCTAGRWLEILPYLVVIVDER---AELRLAAPKDs 189

                          170       180       190
                   ....*....|....*....|....*....|
gi 283133749   827 -------LMRIATIGRSLGLHLVLATQRPQ 849
Cdd:pfam01580  190 emrvedaIVRLAQKGRAAGIHLLLATQRPS 219
FtsK COG1674
DNA segregation ATPase FtsK/SpoIIIE or related protein [Cell cycle control, cell division, ...
 695-874 4.48e-20

DNA segregation ATPase FtsK/SpoIIIE or related protein [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441280 [Multi-domain]  Cd Length: 611  Bit Score: 96.53  E-value: 4.48e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  695 PHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFKgsagLGPLAQLPHALS-VLSnfDVSAVERALEFLRADIH 773
Cdd:COG1674   282 PHLLIAGATGSGKSVCINAMILSLLYKATPDEVRLILIDPKmv-eLSVYNGIPHLLTpVVT--DPKKAANALKWAVREME 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  774 RREVDLQALGV---NSYRDYLASCQAAGTTPRYPE----LLIVVDEFrmlidsmpdamAELM------------RIATIG 834
Cdd:COG1674   359 RRYKLFAKAGVrniAGYNEKVREAKAKGEEEEGLEplpyIVVIIDEL-----------ADLMmvagkeveeaiaRLAQKA 427

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 283133749  835 RSLGLHLVLATQRPqgaiSQD-----IRANIATSICLRVASAQDS 874
Cdd:COG1674   428 RAAGIHLILATQRP----SVDvitglIKANIPSRIAFAVSSKIDS 468
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 695-883 8.06e-17

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 87.06  E-value: 8.06e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  695 PHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFKgSAGLGPLAQLPHALSVLSNfDVSAVERALEFLRADIHR 774
Cdd:PRK10263 1011 PHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPK-MLELSVYEGIPHLLTEVVT-DMKDAANALRWCVNEMER 1088

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  775 REVDLQALGVNS---YRDYLASCQAAG-------------------TTPRYPELLIVVDEFRMLIDSMPDAMAELM-RIA 831
Cdd:PRK10263 1089 RYKLMSALGVRNlagYNEKIAEADRMMrpipdpywkpgdsmdaqhpVLKKEPYIVVLVDEFADLMMTVGKKVEELIaRLA 1168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 283133749  832 TIGRSLGLHLVLATQRPQ-GAISQDIRANIATSICLRVASAQDSYNLLEHESA 883
Cdd:PRK10263 1169 QKARAAGIHLVLATQRPSvDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGA 1221
Yop-YscD_cpl pfam16697
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain ...
 124-199 3.80e-03

Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain of Yop proteins like YscD from Proteobacteria. YscD forms part of the inner membrane component of the bacterial type III secretion injectosome apparatus.


Pssm-ID: 465238 [Multi-domain]  Cd Length: 94  Bit Score: 38.01  E-value: 3.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   124 ILRGPEAGATFPISRGRTSLGRAALparggeqpHHIHLQDPFLKPVHGSFYADSSGIR----------WIEKRPAASEGS 193
Cdd:pfam16697    2 VLSGPHAGAEFPLEGGRYRIGSDPD--------CDIVLSDKEVSRVHLKLEVDDEGWRlddlgsgngtLVNGQRVTELGI 73


                   ....*.
gi 283133749   194 EKAHGS 199
Cdd:pfam16697   74 ALRPGD 79
 
Name Accession Description Interval E-value
T7SS_EccC_a TIGR03924
type VII secretion protein EccCa; This model represents the N-terminal domain or EccCa subunit ...
 601-913 1.29e-46

type VII secretion protein EccCa; This model represents the N-terminal domain or EccCa subunit of the type VII secretion protein EccC as found in the Actinobacteria. Type VII secretion is defined more broadly as including secretion systems for ESAT-6-like proteins in the Firmicutes as well as in the Actinobacteria, but this family does not show close homologs in the Firmicutes. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274858 [Multi-domain]  Cd Length: 658  Bit Score: 179.40  E-value: 1.29e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   601 LCQHADGLSL---EAFCAALENlYRAGCEQEQGALSEGQvhqsahlfSSLQQQNRADDMAVESVLQRWSAQRYASDIRCY 677
Cdd:TIGR03924  342 FGVAPDQLSIaeaEALARRLAR-WRAATAGTVDAPLTGA--------RDLLELLGIGDPATLDVDRLWRPRPGRDRLRVP 412

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   678 LGVSSGGS---LNIGLSEH---GPHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFKGSAGLGPLAQLPHALS 751
Cdd:TIGR03924  413 IGVGDDGEpveLDLKESAEggmGPHGLCIGATGSGKSELLRTLVLGLAATHSPEQLNLVLVDFKGGATFLGLEGLPHVSA 492

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   752 VLSNF--DVSAVERALEFLRADIHRREVDLQALG-VNSYRDYLASCQAAGTTPRYPELLIVVDEFRMLIDSMPDaMAELM 828
Cdd:TIGR03924  493 VITNLadEAPLVDRMQDALAGEMNRRQELLRAAGnFANVAEYEKARAAGADLPPLPALFVVVDEFSELLSQHPD-FADLF 571

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   829 -RIATIGRSLGLHLVLATQRPQGAISQDIRANIATSICLRVASAQDSYNLLEHESAAYISaAHPGAGYVRLPDGRSLPFR 907
Cdd:TIGR03924  572 vAIGRLGRSLGVHLLLASQRLDEGRLRGLESHLSYRIGLKTFSASESRAVLGVPDAYHLP-STPGAGYLKVDTAEPVRFR 650


                   ....*.
gi 283133749   908 APLVDA 913
Cdd:TIGR03924  651 AAYVSG 656
T7_EssCb_Firm TIGR03928
type VII secretion protein EssC, C-terminal domain; This model describes the C-terminal domain, ...
 661-896 2.65e-45

type VII secretion protein EssC, C-terminal domain; This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274860 [Multi-domain]  Cd Length: 1296  Bit Score: 179.80  E-value: 2.65e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   661 VLQRWSAQRYASDIRCYLGVSSGG---SLNIGLSEHGPHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFKGS 737
Cdd:TIGR03928  433 IQERWAKNETYKSLAVPIGLRGKDdivYLNLHEKAHGPHGLVAGTTGSGKSEILQTYILSLAVNFHPHEVAFLLIDYKGG 512

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   738 AGLGPLAQLPHALSVLSNFDVSAVERALEFLRADIHRREVDLQALGVNSYRDYLASCQAAGTTPRYPELLIVVDEFRMLI 817
Cdd:TIGR03928  513 GMANLFKNLPHLLGTITNLDGAQSMRALASIKAELKKRQRLFGENNVNHINQYQKLYKQGKAKEPMPHLFLISDEFAELK 592

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 283133749   818 DSMPDAMAELMRIATIGRSLGLHLVLATQRPQGAISQDIRANIATSICLRVASAQDSYNLLEHESAAYISAahPGAGYV 896
Cdd:TIGR03928  593 SEQPEFMKELVSTARIGRSLGVHLILATQKPSGVVDDQIWSNSRFKLALKVQDASDSNEILKTPDAAEITV--PGRAYL 669
T7SS_EccC_b TIGR03925
type VII secretion protein EccCb; This model represents the C-terminal domain or EccCb subunit ...
 686-925 2.87e-22

type VII secretion protein EccCb; This model represents the C-terminal domain or EccCb subunit of the type VII secretion protein EccC as found in the Actinobacteria. Type VII secretion is defined more broadly as including secretion systems for ESAT-6-like proteins in the Firmicutes as well as in the Actinobacteria, but this family does not show close homologs in the Firmicutes. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274859 [Multi-domain]  Cd Length: 566  Bit Score: 103.15  E-value: 2.87e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   686 LNIGLSEHGPHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFkGSAGLGPLAQLPHALSVLSNFDVSAVERAL 765
Cdd:TIGR03925   71 LVVDLSGAAGHVAIVGAPQSGKSTALRTLILALALTHTPEEVQFYCLDF-GGGGLASLADLPHVGGVAGRLDPERVRRTV 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   766 EFLRADIHRREVDLQALGVNSYRDYLAScQAAGTTPRYP--ELLIVVDEFRMLIDSMPDAMAELMRIATIGRSLGLHLVL 843
Cdd:TIGR03925  150 AEVEGLLRRRERLFRTHGIDSMAQYRAR-RAAGRLPEDPfgDVFLVIDGWGTLRQDFEDLEDKVTDLAARGLAYGVHVVL 228

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   844 ATQRPQGaISQDIRANIATSICLRVASAQDSynLLEHESAAYISAAHPGAGYVrlPDGRSLPFRAPLVDAVPSSSDARPV 923
Cdd:TIGR03925  229 TASRWSE-IRPALRDLIGTRIELRLGDPMDS--EIDRRAAARVPAGRPGRGLT--PDGLHMLIALPRLDGIASVDDLGTR 303


                   ..
gi 283133749   924 QV 925
Cdd:TIGR03925  304 GL 305
FtsK_SpoIIIE pfam01580
FtsK/SpoIIIE family; FtsK has extensive sequence similarity to wide variety of proteins from ...
 690-849 3.69e-22

FtsK/SpoIIIE family; FtsK has extensive sequence similarity to wide variety of proteins from prokaryotes and plasmids, termed the FtsK/SpoIIIE family. This domain contains a putative ATP binding P-loop motif. It is found in the FtsK cell division protein from E. coli and the stage III sporulation protein E SpoIIIE, which has roles in regulation of prespore specific gene expression in B. subtilis. A mutation in FtsK causes a temperature sensitive block in cell division and it is involved in peptidoglycan synthesis or modification. The SpoIIIE protein is implicated in intercellular chromosomal DNA transfer.


Pssm-ID: 279863 [Multi-domain]  Cd Length: 219  Bit Score: 96.68  E-value: 3.69e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   690 LSEHGPHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFKGSAgLGPLAQLPHALSVLSNFDVSAVERALEFLR 769
Cdd:pfam01580   34 LKKMPVHLLIAGATGSGKSVALNTLILSLAYMHTPEEVQLYCIDPKMGE-LSAYEDIPHLLSVPVATDPKRALRALEWLV 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   770 ADIHRREVDLQALGVNSYRDY----------------------LASCQAAGTTPRYPELLIVVDEFrmlIDSMPDAMAE- 826
Cdd:pfam01580  113 DEMERRYALFRALGVRSIAGYngeiaedpldgfgdvflviygvHVMCTAGRWLEILPYLVVIVDER---AELRLAAPKDs 189

                          170       180       190
                   ....*....|....*....|....*....|
gi 283133749   827 -------LMRIATIGRSLGLHLVLATQRPQ 849
Cdd:pfam01580  190 emrvedaIVRLAQKGRAAGIHLLLATQRPS 219
FtsK COG1674
DNA segregation ATPase FtsK/SpoIIIE or related protein [Cell cycle control, cell division, ...
 695-874 4.48e-20

DNA segregation ATPase FtsK/SpoIIIE or related protein [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441280 [Multi-domain]  Cd Length: 611  Bit Score: 96.53  E-value: 4.48e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  695 PHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFKgsagLGPLAQLPHALS-VLSnfDVSAVERALEFLRADIH 773
Cdd:COG1674   282 PHLLIAGATGSGKSVCINAMILSLLYKATPDEVRLILIDPKmv-eLSVYNGIPHLLTpVVT--DPKKAANALKWAVREME 358

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  774 RREVDLQALGV---NSYRDYLASCQAAGTTPRYPE----LLIVVDEFrmlidsmpdamAELM------------RIATIG 834
Cdd:COG1674   359 RRYKLFAKAGVrniAGYNEKVREAKAKGEEEEGLEplpyIVVIIDEL-----------ADLMmvagkeveeaiaRLAQKA 427

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 283133749  835 RSLGLHLVLATQRPqgaiSQD-----IRANIATSICLRVASAQDS 874
Cdd:COG1674   428 RAAGIHLILATQRP----SVDvitglIKANIPSRIAFAVSSKIDS 468
T7_EssCb_Firm TIGR03928
type VII secretion protein EssC, C-terminal domain; This model describes the C-terminal domain, ...
 686-878 6.80e-20

type VII secretion protein EssC, C-terminal domain; This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274860 [Multi-domain]  Cd Length: 1296  Bit Score: 96.98  E-value: 6.80e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   686 LNIGLSEHGpHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFkGSAGLGPLAQLPHALSVLSNFDVSAVERAL 765
Cdd:TIGR03928  803 LTLDLSKDG-HLAIFGSPGYGKSTFLQTLIMSLARQHSPEQLHFYLFDF-GTNGLLPLKKLPHVADYFTLDEEEKIEKLI 880

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   766 EFLRADIHRREVDLQALGVNSYRDYLascQAAGTTprYPELLIVVDEFRMLIDS--MPDAMAELMRIATIGRSLGLHLVL 843
Cdd:TIGR03928  881 RRIKKEIDRRKKLFSEYGVASISMYN---KASGEK--LPQIVIIIDNYDAVKEEpfYEDFEELLIQLAREGASLGIYLVM 955

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 283133749   844 ATQRpQGAISQDIRANIATSICLRVASAQDSYNLL 878
Cdd:TIGR03928  956 TAGR-QNAVRMPLMNNIKTKIALYLIDKSEYRSIV 989
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 695-883 8.06e-17

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 87.06  E-value: 8.06e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  695 PHWLLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDFKgSAGLGPLAQLPHALSVLSNfDVSAVERALEFLRADIHR 774
Cdd:PRK10263 1011 PHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPK-MLELSVYEGIPHLLTEVVT-DMKDAANALRWCVNEMER 1088

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  775 REVDLQALGVNS---YRDYLASCQAAG-------------------TTPRYPELLIVVDEFRMLIDSMPDAMAELM-RIA 831
Cdd:PRK10263 1089 RYKLMSALGVRNlagYNEKIAEADRMMrpipdpywkpgdsmdaqhpVLKKEPYIVVLVDEFADLMMTVGKKVEELIaRLA 1168

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 283133749  832 TIGRSLGLHLVLATQRPQ-GAISQDIRANIATSICLRVASAQDSYNLLEHESA 883
Cdd:PRK10263 1169 QKARAAGIHLVLATQRPSvDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGA 1221
HerA COG0433
Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase ...
 806-873 5.03e-10

Archaeal DNA helicase HerA or a related bacterial ATPase, contains HAS-barrel and ATPase domains [Replication, recombination and repair];


Pssm-ID: 440202 [Multi-domain]  Cd Length: 388  Bit Score: 63.47  E-value: 5.03e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 283133749  806 LLIVVDEFRMLIDSMPDAMAELM-RIATIGRSLGLHLVLATQRPqGAISQDIRANIATSICLRVASAQD 873
Cdd:COG0433   260 LVLVIDEAHLLAPAAPSALLEILeRIAREGRKFGVGLILATQRP-SDIDEDVLSQLGTQIILRLFNPRD 327
T7_EssCb_Firm TIGR03928
type VII secretion protein EssC, C-terminal domain; This model describes the C-terminal domain, ...
 682-896 7.91e-04

type VII secretion protein EssC, C-terminal domain; This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274860 [Multi-domain]  Cd Length: 1296  Bit Score: 44.21  E-value: 7.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   682 SGGSLNIGLSEH-----------GPHWLLGGTTGAGKSQLLRSLVLSAALRyppERLGLILVDFKGSaGLGPLAQLPHAL 750
Cdd:TIGR03928 1073 EEGSIPIGLDEEtvepvyidlteNPHLLIVGESDDGKTNVLKSLLKTLAKQ---EKEKIGLIDSIDR-GLLAYRDLKEVA 1148

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   751 SVLSNFDvsAVERALEFLRADIHRREVDLQALGVNSYrdylascqaagTTPRYPELLIVVDEF----RMLIDSMPDAMAE 826
Cdd:TIGR03928 1149 TYIEEKE--DLKEILAELKEEIELREAAYKEALQNET-----------GEPAFKPILLIIDDLedfiQRTDLEIQDILAL 1215

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 283133749   827 LMriaTIGRSLGLHLVLATQ-----RPQGAISQDIRaNIATSICLRVASAQDSYNLLEHESAAYISaahPGAGYV 896
Cdd:TIGR03928 1216 IM---KNGKKLGIHFIVAGThselsKSYDGVPKEIK-QLRTGILGMRKSDQSFFKLPFTRSEKELE---PGEGYF 1283
VirD4 COG3505
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ...
 804-889 1.14e-03

Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442728 [Multi-domain]  Cd Length: 402  Bit Score: 43.05  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  804 PELLIVVDEFRML--IDSMPDAMAElmriatiGRSLGLHLVLATQ-RPQG------AISQDIRANIATSICLRVAsaqds 874
Cdd:COG3505   247 RPVLLLLDEFANLgrLPSLETLLAT-------GRGYGIRLVLILQsLAQLeaiygeEGAETILGNCGTKIFLGVN----- 314

                          90
                  ....*....|....*
gi 283133749  875 ynllEHESAAYISAA 889
Cdd:COG3505   315 ----DPETAEYLSEL 325
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
 378-932 2.39e-03

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 42.55  E-value: 2.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  378 YLRGRNLPLGALEKQDAPHYLPLPTPVLGHylKLEEAHLRAYLVQLVAGYPGSVHVLLAEAHNSAQKRMNALLQTLAVVP 457
Cdd:COG3321   841 WVAGVPVDWSALYPGRGRRRVPLPTYPFQR--EDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAA 918

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  458 GVSVHCLPGTQQEKYLQALQSSLQSELSSSVPPLILMPQHASAVYAPLLTALTSGAIAEGSQSRALSSPREQKMNAPALC 537
Cdd:COG3321   919 LALAAAALAALLALVALAAAAAALLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAA 998

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  538 VLGSAEGDNSAHAPGALFGAAWVECASEGSHRQSIRYRAQGYAMPPVQPTEGVYQVHPLACEGLCQHADGLSLEAFCAAL 617
Cdd:COG3321   999 AAALALLAAAALLLAAAAAAAALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELA 1078

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  618 EnlyragcEQEQGALSEGQVHQSAHLFSSLQQQNRADDMAVESVLQRWSAQRYASDIRCYLGVSSGGSLNIGLSEHGPHW 697
Cdd:COG3321  1079 L-------AAAALALAAALAAAALALALAALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALA 1151

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  698 LLGGTTGAGKSQLLRSLVLSAALRYPPERLGLILVDfkGSAGLGPLAQLPHALSVLSNFDVSAVERALEFLRADIHRREV 777
Cdd:COG3321  1152 LAAAAAALAAALAAALLAAAALLLALALALAAALAA--ALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAA 1229

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749  778 DLQALGVNSYRDYLASCQAAGTTPRYPELLIVVDEFRMLIDSMPDAMAELMRIATIGRSLGLHLVLATQRPQGAISQDIR 857
Cdd:COG3321  1230 AAALALLALAAAAAAVAALAAAAAALLAALAALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAA 1309

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 283133749  858 ANIATSICLRVASAQDSYNLLEHESAAYISAAHPGAGYVRLPDGRSLPFRAPLVDAVPSSSDARPVQVLGLEEGG 932
Cdd:COG3321  1310 AAAAAAAAAAALAAALLAAALAALAAAVAAALALAAAAAAAAAAAAAAAAAAALAAAAGAAAAAAALALAALAAA 1384
Yop-YscD_cpl pfam16697
Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain ...
 124-199 3.80e-03

Inner membrane component of T3SS, cytoplasmic domain; Yop-YscD-cpl is the cytoplasmic domain of Yop proteins like YscD from Proteobacteria. YscD forms part of the inner membrane component of the bacterial type III secretion injectosome apparatus.


Pssm-ID: 465238 [Multi-domain]  Cd Length: 94  Bit Score: 38.01  E-value: 3.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 283133749   124 ILRGPEAGATFPISRGRTSLGRAALparggeqpHHIHLQDPFLKPVHGSFYADSSGIR----------WIEKRPAASEGS 193
Cdd:pfam16697    2 VLSGPHAGAEFPLEGGRYRIGSDPD--------CDIVLSDKEVSRVHLKLEVDDEGWRlddlgsgngtLVNGQRVTELGI 73


                   ....*.
gi 283133749   194 EKAHGS 199
Cdd:pfam16697   74 ALRPGD 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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