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Conserved domains on  [gi|2801411|gb|AAC39948|]
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sarcosine oxidase [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 8-388 0e+00

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


:

Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 714.68  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411      8 WDAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPHSRGSSHGQSRIIRKAYPEDFYTMMMKECYQTWAQLEREAGTQLH 87
Cdd:TIGR01377   1 FDVIVVGAGIMGCFAAYHLAKHGKKTLLLEQFDLPHSRGSSHGQSRIIRKAYPEDFYTPMMLECYQLWAQLEKEAGTKLH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411     88 RQTELLLLGTKENPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGEVGLLDKTGGVLYADKALRALQHIICHLGG 167
Cdd:TIGR01377  81 RQTGLLLLGPKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRALQELAEAHGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    168 TVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRLLHPLGIELPLQTLRINVCYWREKVPGSYGVSQAFPCI 246
Cdd:TIGR01377 161 TVRDGTKVVEIEPtELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPLRINVCYWREKEPGSYGVSQAFPCF 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    247 LGLDLAPhHIYGLPASEYPGLMKICYHHGDNVDPEERDCPKTfSDIQDVQILCHFVRDHLPGLRAEPDIMERCMYTNTPD 326
Cdd:TIGR01377 241 LVLGLNP-HIYGLPSFEYPGLMKVYYHHGQQIDPDERDCPFG-ADIEDVQILRKFVRDHLPGLNGEPKKGEVCMYTNTPD 318

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2801411    327 EHFILDWHPKYDNIVIGAGFSGHGFTLAPVVGKILYELSMKLPPSYDLAPFRMSRFSTLSKA 388
Cdd:TIGR01377 319 EHFVIDLHPKYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRFALKKKA 380
 
Name Accession Description Interval E-value
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 8-388 0e+00

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 714.68  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411      8 WDAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPHSRGSSHGQSRIIRKAYPEDFYTMMMKECYQTWAQLEREAGTQLH 87
Cdd:TIGR01377   1 FDVIVVGAGIMGCFAAYHLAKHGKKTLLLEQFDLPHSRGSSHGQSRIIRKAYPEDFYTPMMLECYQLWAQLEKEAGTKLH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411     88 RQTELLLLGTKENPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGEVGLLDKTGGVLYADKALRALQHIICHLGG 167
Cdd:TIGR01377  81 RQTGLLLLGPKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRALQELAEAHGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    168 TVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRLLHPLGIELPLQTLRINVCYWREKVPGSYGVSQAFPCI 246
Cdd:TIGR01377 161 TVRDGTKVVEIEPtELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPLRINVCYWREKEPGSYGVSQAFPCF 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    247 LGLDLAPhHIYGLPASEYPGLMKICYHHGDNVDPEERDCPKTfSDIQDVQILCHFVRDHLPGLRAEPDIMERCMYTNTPD 326
Cdd:TIGR01377 241 LVLGLNP-HIYGLPSFEYPGLMKVYYHHGQQIDPDERDCPFG-ADIEDVQILRKFVRDHLPGLNGEPKKGEVCMYTNTPD 318

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2801411    327 EHFILDWHPKYDNIVIGAGFSGHGFTLAPVVGKILYELSMKLPPSYDLAPFRMSRFSTLSKA 388
Cdd:TIGR01377 319 EHFVIDLHPKYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRFALKKKA 380
solA PRK11259
N-methyl-L-tryptophan oxidase;
9-383 3.74e-96

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 291.74  E-value: 3.74e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411     9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPHSRGSSHGQSRIIRKAYPED-FYTMMMKECYQTWAQLEREAGTQLH 87
Cdd:PRK11259   5 DVIVIGLGSMGSAAGYYLARRGLRVLGLDRFMPPHQQGSSHGDTRIIRHAYGEGpAYVPLVLRAQELWRELERESGEPLF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    88 RQTELLLLGTKENPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGEVGLLDKTGGVLYADKALRALQHIICHLGG 167
Cdd:PRK11259  85 VRTGVLNLGPADSDFLANSIRSARQHGLPHEVLDAAEIRRRFPQFRLPDGYIALFEPDGGFLRPELAIKAHLRLAREAGA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411   168 TVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRLLHPLGieLPLQTLRiNVCYWREKVPGsYGVSQAFPCI 246
Cdd:PRK11259 165 ELLFNEPVTAIEAdGDGVTVTTADGTYEAKKLVVSAGAWVKDLLPPLE--LPLTPVR-QVLAWFQADGR-YSEPNRFPAF 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411   247 LGLDLAPHHIYGLPASEYPGLmKICYHHG--DNVDPEERDcpKTFSDIQDVQILCHFVRDHLPG----LRAEPdimerCM 320
Cdd:PRK11259 241 IWEVPDGDQYYGFPAENGPGL-KIGKHNGgqEITSPDERD--RFVTVAEDGAELRPFLRNYLPGvgpcLRGAA-----CT 312

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2801411   321 YTNTPDEHFILDWHPKYDNIVIGAGFSGHGFTLAPVVGKILYELSMKLPPSYDLAPFRMSRFS 383
Cdd:PRK11259 313 YTNTPDEHFIIDTLPGHPNVLVASGCSGHGFKFASVLGEILADLAQDGTSDFDLSPFSLSRFA 375
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
9-381 1.80e-65

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 212.46  E-value: 1.80e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPhsRGSSHGQSRIIRKAYPED---FYTMMMKECYQTWAQLEREAGTQ 85
Cdd:COG0665   4 DVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPG--SGASGRNAGQLRPGLAALadrALVRLAREALDLWRELAAELGID 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411   86 L-HRQTELLLLGTKENP--GLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGEVGLLDKTGGVLYADKALRALQHII 162
Cdd:COG0665  82 CdFRRTGVLYLARTEAElaALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALARAA 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411  163 CHLGGTVCDGEKVVEIRP--GLPVTVKTTLKSYQANSLVITAGPWTNRLLHPLGIELPLQTLRinvcywrekvpgsyGVS 240
Cdd:COG0665 162 RAAGVRIREGTPVTGLERegGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVR--------------GYV 227

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411  241 QAFPCILGLDLAP----HHIYGLPASEypGLMKI-CYHHGDNVDPEERDcpktfsdiQDVQILCHFVRDHLPGLRAEPDI 315
Cdd:COG0665 228 LVTEPLPDLPLRPvlddTGVYLRPTAD--GRLLVgGTAEPAGFDRAPTP--------ERLEALLRRLRRLFPALADAEIV 297

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2801411  316 MER-CMYTNTPDEHFILDWHPKYDNIVIGAGFSGHGFTLAPVVGKILYELSMKLPPSYDLAPFRMSR 381
Cdd:COG0665 298 RAWaGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 9-364 1.29e-47

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 165.26  E-value: 1.29e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411      9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPhSRGSSHGQSRIIR---KAYPEDFYTMMMKECYQTWAQLEREAGTQ 85
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDP-GSGASGRNAGLIHpglRYLEPSELARLALEALDLWEELEEELGID 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411     86 L-HRQTELLLLGTKE-NPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGevGLLDKTGGVLYADKALRALQHIIC 163
Cdd:pfam01266  80 CgFRRCGVLVLARDEeEEALEKLLAALRRLGVPAELLDAEELRELEPLLPGLRG--GLFYPDGGHVDPARLLRALARAAE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    164 HLGGTVCDGEKVVEIRPGLPVTVKTTLKSYQAnsLVITAGPWTnRLLHPLGIELPLQTLR---INVCYWREKVPGSYgvs 240
Cdd:pfam01266 158 ALGVRIIEGTEVTGIEEEGGVWGVVTTGEADA--VVNAAGAWA-DLLALPGLRLPVRPVRgqvLVLEPLPEALLILP--- 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    241 qafpcILGLDLAPHHIYGLPASEypGLMKICYHHgDNVDPEERDcpktfSDIQDVQILCHFVRDHLPGLRaepDIMER-- 318
Cdd:pfam01266 232 -----VPITVDPGRGVYLRPRAD--GRLLLGGTD-EEDGFDDPT-----PDPEEIEELLEAARRLFPALA---DIERAwa 295

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 2801411    319 CMYTnTPDEHFILDwHPKYDNIVIGAGFSGHGFTLAPVVGKILYEL 364
Cdd:pfam01266 296 GLRP-LPDGLPIIG-RPGSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
 
Name Accession Description Interval E-value
soxA_mon TIGR01377
sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of ...
 8-388 0e+00

sarcosine oxidase, monomeric form; Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms [Energy metabolism, Amino acids and amines]


Pssm-ID: 130444 [Multi-domain]  Cd Length: 380  Bit Score: 714.68  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411      8 WDAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPHSRGSSHGQSRIIRKAYPEDFYTMMMKECYQTWAQLEREAGTQLH 87
Cdd:TIGR01377   1 FDVIVVGAGIMGCFAAYHLAKHGKKTLLLEQFDLPHSRGSSHGQSRIIRKAYPEDFYTPMMLECYQLWAQLEKEAGTKLH 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411     88 RQTELLLLGTKENPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGEVGLLDKTGGVLYADKALRALQHIICHLGG 167
Cdd:TIGR01377  81 RQTGLLLLGPKENQFLKTIQATLSRHGLEHELLSSKQLKQRFPNIRVPRNEVGLLDPNGGVLYAEKALRALQELAEAHGA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    168 TVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRLLHPLGIELPLQTLRINVCYWREKVPGSYGVSQAFPCI 246
Cdd:TIGR01377 161 TVRDGTKVVEIEPtELLVTVKTTKGSYQANKLVVTAGAWTSKLLSPLGIEIPLQPLRINVCYWREKEPGSYGVSQAFPCF 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    247 LGLDLAPhHIYGLPASEYPGLMKICYHHGDNVDPEERDCPKTfSDIQDVQILCHFVRDHLPGLRAEPDIMERCMYTNTPD 326
Cdd:TIGR01377 241 LVLGLNP-HIYGLPSFEYPGLMKVYYHHGQQIDPDERDCPFG-ADIEDVQILRKFVRDHLPGLNGEPKKGEVCMYTNTPD 318

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2801411    327 EHFILDWHPKYDNIVIGAGFSGHGFTLAPVVGKILYELSMKLPPSYDLAPFRMSRFSTLSKA 388
Cdd:TIGR01377 319 EHFVIDLHPKYDNVVIGAGFSGHGFKLAPVVGKILAELAMKLKPSYDLAIFSLNRFALKKKA 380
solA PRK11259
N-methyl-L-tryptophan oxidase;
9-383 3.74e-96

N-methyl-L-tryptophan oxidase;


Pssm-ID: 236887 [Multi-domain]  Cd Length: 376  Bit Score: 291.74  E-value: 3.74e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411     9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPHSRGSSHGQSRIIRKAYPED-FYTMMMKECYQTWAQLEREAGTQLH 87
Cdd:PRK11259   5 DVIVIGLGSMGSAAGYYLARRGLRVLGLDRFMPPHQQGSSHGDTRIIRHAYGEGpAYVPLVLRAQELWRELERESGEPLF 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    88 RQTELLLLGTKENPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGEVGLLDKTGGVLYADKALRALQHIICHLGG 167
Cdd:PRK11259  85 VRTGVLNLGPADSDFLANSIRSARQHGLPHEVLDAAEIRRRFPQFRLPDGYIALFEPDGGFLRPELAIKAHLRLAREAGA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411   168 TVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRLLHPLGieLPLQTLRiNVCYWREKVPGsYGVSQAFPCI 246
Cdd:PRK11259 165 ELLFNEPVTAIEAdGDGVTVTTADGTYEAKKLVVSAGAWVKDLLPPLE--LPLTPVR-QVLAWFQADGR-YSEPNRFPAF 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411   247 LGLDLAPHHIYGLPASEYPGLmKICYHHG--DNVDPEERDcpKTFSDIQDVQILCHFVRDHLPG----LRAEPdimerCM 320
Cdd:PRK11259 241 IWEVPDGDQYYGFPAENGPGL-KIGKHNGgqEITSPDERD--RFVTVAEDGAELRPFLRNYLPGvgpcLRGAA-----CT 312

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2801411   321 YTNTPDEHFILDWHPKYDNIVIGAGFSGHGFTLAPVVGKILYELSMKLPPSYDLAPFRMSRFS 383
Cdd:PRK11259 313 YTNTPDEHFIIDTLPGHPNVLVASGCSGHGFKFASVLGEILADLAQDGTSDFDLSPFSLSRFA 375
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
9-381 1.80e-65

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 212.46  E-value: 1.80e-65
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPhsRGSSHGQSRIIRKAYPED---FYTMMMKECYQTWAQLEREAGTQ 85
Cdd:COG0665   4 DVVVIGGGIAGLSTAYHLARRGLDVTVLERGRPG--SGASGRNAGQLRPGLAALadrALVRLAREALDLWRELAAELGID 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411   86 L-HRQTELLLLGTKENP--GLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGEVGLLDKTGGVLYADKALRALQHII 162
Cdd:COG0665  82 CdFRRTGVLYLARTEAElaALRAEAEALRALGLPVELLDAAELREREPGLGSPDYAGGLYDPDDGHVDPAKLVRALARAA 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411  163 CHLGGTVCDGEKVVEIRP--GLPVTVKTTLKSYQANSLVITAGPWTNRLLHPLGIELPLQTLRinvcywrekvpgsyGVS 240
Cdd:COG0665 162 RAAGVRIREGTPVTGLERegGRVTGVRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVR--------------GYV 227

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411  241 QAFPCILGLDLAP----HHIYGLPASEypGLMKI-CYHHGDNVDPEERDcpktfsdiQDVQILCHFVRDHLPGLRAEPDI 315
Cdd:COG0665 228 LVTEPLPDLPLRPvlddTGVYLRPTAD--GRLLVgGTAEPAGFDRAPTP--------ERLEALLRRLRRLFPALADAEIV 297

                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2801411  316 MER-CMYTNTPDEHFILDWHPKYDNIVIGAGFSGHGFTLAPVVGKILYELSMKLPPSYDLAPFRMSR 381
Cdd:COG0665 298 RAWaGLRPMTPDGLPIIGRLPGAPGLYVATGHGGHGVTLAPAAGRLLADLILGGEPPLDLAPFSPDR 364
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 9-364 1.29e-47

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 165.26  E-value: 1.29e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411      9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPhSRGSSHGQSRIIR---KAYPEDFYTMMMKECYQTWAQLEREAGTQ 85
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDP-GSGASGRNAGLIHpglRYLEPSELARLALEALDLWEELEEELGID 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411     86 L-HRQTELLLLGTKE-NPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGevGLLDKTGGVLYADKALRALQHIIC 163
Cdd:pfam01266  80 CgFRRCGVLVLARDEeEEALEKLLAALRRLGVPAELLDAEELRELEPLLPGLRG--GLFYPDGGHVDPARLLRALARAAE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    164 HLGGTVCDGEKVVEIRPGLPVTVKTTLKSYQAnsLVITAGPWTnRLLHPLGIELPLQTLR---INVCYWREKVPGSYgvs 240
Cdd:pfam01266 158 ALGVRIIEGTEVTGIEEEGGVWGVVTTGEADA--VVNAAGAWA-DLLALPGLRLPVRPVRgqvLVLEPLPEALLILP--- 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    241 qafpcILGLDLAPHHIYGLPASEypGLMKICYHHgDNVDPEERDcpktfSDIQDVQILCHFVRDHLPGLRaepDIMER-- 318
Cdd:pfam01266 232 -----VPITVDPGRGVYLRPRAD--GRLLLGGTD-EEDGFDDPT-----PDPEEIEELLEAARRLFPALA---DIERAwa 295

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 2801411    319 CMYTnTPDEHFILDwHPKYDNIVIGAGFSGHGFTLAPVVGKILYEL 364
Cdd:pfam01266 296 GLRP-LPDGLPIIG-RPGSPGLYLATGHGGHGLTLAPGIGKLLAEL 339
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
9-267 1.15e-15

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 77.88  E-value: 1.15e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    9 DAIVIGAGIQGCFTAYHLAK-HSKSVLLLEQffLPH-SRGSSHGQSRIIRKAYPEDFYTMMMKEC---YQTWAQLEREAG 83
Cdd:COG0579   6 DVVIIGAGIVGLALARELSRyEDLKVLVLEK--EDDvAQESSGNNSGVIHAGLYYTPGSLKARLCvegNELFYELCRELG 83

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411   84 TQlHRQTELLLLGTKEN--PGLKTIQATLSRQGIDH-EYLSSVDLKQRFPNIRfTRGEVGLLDKTGGVLYADKALRALQH 160
Cdd:COG0579  84 IP-FKRCGKLVVATGEEevAFLEKLYERGKANGVPGlEILDREELRELEPLLS-DEGVAALYSPSTGIVDPGALTRALAE 161

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411  161 IICHLGGTVCDGEKVVEIRP---GlpVTVKTTLKSYQANSLVITAGPWTNRLLHPLGIELPLQTlrinvcywrekVP--G 235
Cdd:COG0579 162 NAEANGVELLLNTEVTGIERegdG--WEVTTNGGTIRARFVINAAGLYADRLAQMAGIGKDFGI-----------FPvkG 228

                       250       260       270
                ....*....|....*....|....*....|....
gi 2801411  236 SYgvsqafpCIL--GLDLAPHHIYGLPASEYPGL 267
Cdd:COG0579 229 EY-------LVLdkPAELVNAKVYPVPDPGAPFL 255
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 8-38 3.03e-06

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 48.47  E-value: 3.03e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2801411      8 WDAIVIGAGIQGCFTAYHLAKHSKSVLLLEQ 38
Cdd:TIGR02032   1 YDVVVVGAGPAGASAAYRLADKGLRVLLLEK 31
HpnW_proposed TIGR03364
FAD dependent oxidoreductase TIGR03364; This clade of FAD dependent oxidoreductases (members ...
 9-134 1.96e-05

FAD dependent oxidoreductase TIGR03364; This clade of FAD dependent oxidoreductases (members of the pfam01266 family) is syntenically associated with a family of proposed phosphonatase-like enzymes (TIGR03351) and is also found (less frequently) in association with phosphonate transporter components. A likely role for this enzyme involves the oxidative deamination of an aminophosphonate differring slightly from 2-aminoethylphosphonate, possibly 1-hydroxy-2-aminoethylphosphonate (see the comments for TIGR03351). Many members of the larger FAD dependent oxidoreductase family act as amino acid oxidative deaminases.


Pssm-ID: 132407 [Multi-domain]  Cd Length: 365  Bit Score: 46.14  E-value: 1.96e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411      9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQffLPHSRGSS---HGQSRIIRKAyPEDFYTMMMkECYQTWAQLEREAGTQ 85
Cdd:TIGR03364   2 DLIIVGAGILGLAHAYAAARRGLSVTVIER--SSRAQGASvrnFGQVWPTGQA-PGPAWDRAR-RSREIWLELAAKAGIW 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2801411     86 LhRQTELLLLGTKEnPGLKTIQ---ATLSRQGIDHEYLSSVDLKQRFPNIRF 134
Cdd:TIGR03364  78 V-RENGSLHLARTE-EELAVLEefaATREPAEYRVELLTPAEVAAKFPALRL 127
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 9-152 3.26e-05

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 45.99  E-value: 3.26e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411     9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPHSRGSSHGQ--------------SRIIRKAYpedFYTMmmkecyQT 74
Cdd:PRK01747 262 DAAIIGGGIAGAALALALARRGWQVTLYEADEAPAQGASGNRQgalypllskddnalSRFFRAAF---LFAR------RF 332

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2801411    75 WAQLEREAGTQLHRQTELLLLGtkENPGLKTIQATLSRQGIDHEYLSSVDLKQrfpnirfTRGEVGLLDKTGGVLYAD 152
Cdd:PRK01747 333 YDALPAAGVAFDHDWCGVLQLA--WDEKSAEKIAKMLALGLPAELARALDAEE-------AEELAGLPVPCGGIFYPQ 401
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
9-220 6.33e-05

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 44.81  E-value: 6.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411     9 DAIVIGAGIQGCFTAYHLAK--HSKSVLLLEqfflphsrgsshgqsriirkaypedfytmmmKE----CYQTW------- 75
Cdd:PRK11728   4 DFVIIGGGIVGLSTAMQLQEryPGARIAVLE-------------------------------KEsgpaRHQTGhnsgvih 52

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411    76 -----------AQLEREAGTQL----------HRQTELLLLGT--KENPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNI 132
Cdd:PRK11728  53 agvyytpgslkARFCRRGNEATkafcdqhgipYEECGKLLVATseLELERMEALYERARANGIEVERLDAEELREREPNI 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2801411   133 rftRGEVGLL-DKTGGVLYADKAlRALQHIICHLGGTVCDGEKVVEIRP-GLPVTVKTTLKSYQANSLVITAGPWTNRLL 210
Cdd:PRK11728 133 ---RGLGAIFvPSTGIVDYRAVA-EAMAELIQARGGEIRLGAEVTALDEhANGVVVRTTQGEYEARTLINCAGLMSDRLA 208

                        250
                 ....*....|
gi 2801411   211 HPLGIELPLQ 220
Cdd:PRK11728 209 KMAGLEPDFR 218
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
12-38 8.80e-05

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 40.21  E-value: 8.80e-05
                          10        20
                  ....*....|....*....|....*..
gi 2801411     12 VIGAGIQGCFTAYHLAKHSKSVLLLEQ 38
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEK 27
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
9-38 5.79e-04

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 41.70  E-value: 5.79e-04
                        10        20        30
                ....*....|....*....|....*....|
gi 2801411    9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQ 38
Cdd:COG3573   7 DVIVVGAGLAGLVAAAELADAGRRVLLLDQ 36
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 9-38 1.75e-03

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 40.27  E-value: 1.75e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 2801411     9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQ 38
Cdd:PRK12834   6 DVIVVGAGLAGLVAAAELADAGKRVLLLDQ 35
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 8-38 2.05e-03

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 40.22  E-value: 2.05e-03
                        10        20        30
                ....*....|....*....|....*....|.
gi 2801411    8 WDAIVIGAGIQGCFTAYHLAKHSKSVLLLEQ 38
Cdd:COG1233   4 YDVVVIGAGIGGLAAAALLARAGYRVTVLEK 34
NadB COG0029
Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the ...
 9-36 2.06e-03

Aspartate oxidase [Coenzyme transport and metabolism]; Aspartate oxidase is part of the Pathway/BioSystem: NAD biosynthesis


Pssm-ID: 439800 [Multi-domain]  Cd Length: 521  Bit Score: 40.09  E-value: 2.06e-03
                        10        20
                ....*....|....*....|....*...
gi 2801411    9 DAIVIGAGIQGCFTAYHLAKHsKSVLLL 36
Cdd:COG0029   6 DVLVIGSGIAGLSAALKLAER-GRVTLL 32
PRK10015 PRK10015
oxidoreductase; Provisional
 6-50 4.05e-03

oxidoreductase; Provisional


Pssm-ID: 182194 [Multi-domain]  Cd Length: 429  Bit Score: 39.19  E-value: 4.05e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 2801411     6 DFWDAIVIGAGIQGCFTAYHLAKHSKSVLLLEqfflphsRGSSHG 50
Cdd:PRK10015   4 DKFDAIVVGAGVAGSVAALVMARAGLDVLVIE-------RGDSAG 41
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 8-38 4.98e-03

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 39.06  E-value: 4.98e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 2801411     8 WDAIVIGAGIQGCFTAYHLAKHSKSVLLLEQ 38
Cdd:PTZ00367  34 YDVIIVGGSIAGPVLAKALSKQGRKVLMLER 64
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 8-37 6.15e-03

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 38.66  E-value: 6.15e-03
                        10        20        30
                ....*....|....*....|....*....|.
gi 2801411    8 WDAIVIGAGIQGCFTAYHLAKH-SKSVLLLE 37
Cdd:COG2303   5 YDYVIVGAGSAGCVLANRLSEDaGLRVLLLE 35
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 9-38 6.19e-03

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 38.66  E-value: 6.19e-03
                        10        20        30
                ....*....|....*....|....*....|
gi 2801411    9 DAIVIGAGIQGCFTAYHLAKHSKSVLLLEQ 38
Cdd:COG1232   3 RVAVIGGGIAGLTAAYRLAKAGHEVTVLEA 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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