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Conserved domains on  [gi|2781213]
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Chain A, FIBRINOGEN

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Fib_alpha super family cl12358
Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation ...
 1-62 1.02e-18

Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma).


The actual alignment was detected with superfamily member pfam08702:

Pssm-ID: 462570  Cd Length: 143  Bit Score: 74.50  E-value: 1.02e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2781213      1 VSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALARE 62
Cdd:pfam08702  82 SSSMLEERIAYIKETVDTQESNIRVLQNILDSNRQKIQRLEQDIDQLERKCKEPCKDSVEIQ 143
 
Name Accession Description Interval E-value
Fib_alpha pfam08702
Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation ...
 1-62 1.02e-18

Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma).


Pssm-ID: 462570  Cd Length: 143  Bit Score: 74.50  E-value: 1.02e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2781213      1 VSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALARE 62
Cdd:pfam08702  82 SSSMLEERIAYIKETVDTQESNIRVLQNILDSNRQKIQRLEQDIDQLERKCKEPCKDSVEIQ 143
 
Name Accession Description Interval E-value
Fib_alpha pfam08702
Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation ...
 1-62 1.02e-18

Fibrinogen alpha/beta chain family; Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma).


Pssm-ID: 462570  Cd Length: 143  Bit Score: 74.50  E-value: 1.02e-18
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2781213      1 VSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALARE 62
Cdd:pfam08702  82 SSSMLEERIAYIKETVDTQESNIRVLQNILDSNRQKIQRLEQDIDQLERKCKEPCKDSVEIQ 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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