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Conserved domains on  [gi|27657705|gb|AAO18189|]
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prothymosin alpha protein [Homo sapiens]

Protein Classification

prothymosin alpha( domain architecture ID 10505379)

prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Prothymosin pfam03247
Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small ...
 2-109 5.37e-10

Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small acidic nuclear proteins that are thought to be involved in cell cycle progression, proliferation, and cell differentiation.


:

Pssm-ID: 460859 [Multi-domain]  Cd Length: 109  Bit Score: 52.22  E-value: 5.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27657705     2 SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNA-NEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEVDGDEDE 80
Cdd:pfam03247   1 SDTAVDTASELSTKDLKEKKEVVEEAEKGKDAPANGNAeNEENGAQEAEEEVEFEEEEDEEEEEEEEEEGEEEDGEEEEE 80

                          90       100
                  ....*....|....*....|....*....
gi 27657705    81 EAESATGKRAAEDDEDDDVDTKKQKTDED 109
Cdd:pfam03247  81 EAEGAAVKRAAEDEEDDDVETKKQKTEEG 109
 
Name Accession Description Interval E-value
Prothymosin pfam03247
Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small ...
 2-109 5.37e-10

Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small acidic nuclear proteins that are thought to be involved in cell cycle progression, proliferation, and cell differentiation.


Pssm-ID: 460859 [Multi-domain]  Cd Length: 109  Bit Score: 52.22  E-value: 5.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27657705     2 SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNA-NEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEVDGDEDE 80
Cdd:pfam03247   1 SDTAVDTASELSTKDLKEKKEVVEEAEKGKDAPANGNAeNEENGAQEAEEEVEFEEEEDEEEEEEEEEEGEEEDGEEEEE 80

                          90       100
                  ....*....|....*....|....*....
gi 27657705    81 EAESATGKRAAEDDEDDDVDTKKQKTDED 109
Cdd:pfam03247  81 EAEGAAVKRAAEDEEDDDVETKKQKTEEG 109
 
Name Accession Description Interval E-value
Prothymosin pfam03247
Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small ...
 2-109 5.37e-10

Prothymosin/parathymosin family; Prothymosin alpha and parathymosin are two ubiquitous small acidic nuclear proteins that are thought to be involved in cell cycle progression, proliferation, and cell differentiation.


Pssm-ID: 460859 [Multi-domain]  Cd Length: 109  Bit Score: 52.22  E-value: 5.37e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27657705     2 SDAAVDTSSEITTKDLKEKKEVVEEAENGRDAPANGNA-NEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEVDGDEDE 80
Cdd:pfam03247   1 SDTAVDTASELSTKDLKEKKEVVEEAEKGKDAPANGNAeNEENGAQEAEEEVEFEEEEDEEEEEEEEEEGEEEDGEEEEE 80

                          90       100
                  ....*....|....*....|....*....
gi 27657705    81 EAESATGKRAAEDDEDDDVDTKKQKTDED 109
Cdd:pfam03247  81 EAEGAAVKRAAEDEEDDDVETKKQKTEEG 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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