|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
1-319 |
0e+00 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 598.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 1 MKRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEE 80
Cdd:PRK03202 1 MKRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFPEFKDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 81 GQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSH 160
Cdd:PRK03202 81 GRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTASSH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 161 ERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGVGSGVDFGRQIQEATGF 240
Cdd:PRK03202 161 ERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKGRERGKKHAIIVVAEGVMPAEELAKEIEERTGL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 241 ETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIAEALAN-KHTIDQRMYALSKELSI 319
Cdd:PRK03202 241 ETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGIQNNKIVHVPIEEAVENmKHPFDKDLYELAKKLSI 320
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-318 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 568.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 2 KRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEG 81
Cdd:cd00763 1 KRIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARFPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 82 QKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHE 161
Cdd:cd00763 81 QAKAIEQLKKHGIDALVVIGGDGSYMGAMRLTEHGFPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSSHQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 162 RTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGVGSGVDFGRQIQEATGFE 241
Cdd:cd00763 161 RISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAGIERGKKHAIVVVAEGVYDVDELAKEIEEATGFE 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 27573984 242 TRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIAEALANKHTIDQRMYALSKELS 318
Cdd:cd00763 241 TRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGGLAVGIQNEQLVHHDIIDAIENMKPFKKDWLALAKKLS 317
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
1-319 |
0e+00 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 503.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 1 MKRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEE 80
Cdd:COG0205 1 MKRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPFKTEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 81 GQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTE-HGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATS 159
Cdd:COG0205 81 GREKALENLKKLGIDALVVIGGDGSLDGAAKLAEeYGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRDTAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 160 HERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGV--------------- 224
Cdd:COG0205 161 HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRGKGYSIIVVAEGAgdedgeavleadtda 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 225 -------GSGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIA 297
Cdd:COG0205 241 fghvrlgGIGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRGEIVLVPLE 320
|
330 340
....*....|....*....|....
gi 27573984 298 EALANKHTID--QRMYALSKELSI 319
Cdd:COG0205 321 EVANKEKPVDpdSPLIQLARELGI 344
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
3-300 |
3.90e-178 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 494.17 E-value: 3.90e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 3 RIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEGQ 82
Cdd:TIGR02482 1 KIGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRRGYKGLINGKIEPLESKNVSGIIHRGGTILGTARCPEFKTEEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 83 KKGIEQLKKHGIEGLVVIGGDGSYQGAKKLT-EHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHE 161
Cdd:TIGR02482 81 EKAVENLKKLGIEGLVVIGGDGSYTGAQKLYeEGGIPVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAVDKIRDTATSHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 162 RTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEG--VGSGVDFGRQIQEATG 239
Cdd:TIGR02482 161 RAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFDYDIDELIQRLKEQHEAGKKHSIIIVAEGniVGSAKEVAKKIEEKTG 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 27573984 240 FETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIAEAL 300
Cdd:TIGR02482 241 IETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLEGKGGVMIGIQNNKIVTHPIEEAL 301
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
3-273 |
2.50e-170 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 473.36 E-value: 2.50e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 3 RIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEGQ 82
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 83 KKGIEQLKKHGIEGLVVIGGDGSYQGAKKLT-EHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHE 161
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSeERGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSHN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 162 RTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHeRGKKHSIIIVAEGVGSGVDFGRQIQEATGFE 241
Cdd:pfam00365 161 RVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELR-KGKRFSIIVVAEGASDGEFLAKLIEEGTGIE 239
|
250 260 270
....*....|....*....|....*....|..
gi 27573984 242 TRVTVLGHVQRGGSPTAFDRVLASRLGARAVE 273
Cdd:pfam00365 240 TRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
1-319 |
0e+00 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 598.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 1 MKRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEE 80
Cdd:PRK03202 1 MKRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFPEFKDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 81 GQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSH 160
Cdd:PRK03202 81 GRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTASSH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 161 ERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGVGSGVDFGRQIQEATGF 240
Cdd:PRK03202 161 ERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKGRERGKKHAIIVVAEGVMPAEELAKEIEERTGL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 241 ETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIAEALAN-KHTIDQRMYALSKELSI 319
Cdd:PRK03202 241 ETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGIQNNKIVHVPIEEAVENmKHPFDKDLYELAKKLSI 320
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-318 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 568.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 2 KRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEG 81
Cdd:cd00763 1 KRIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARFPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 82 QKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHE 161
Cdd:cd00763 81 QAKAIEQLKKHGIDALVVIGGDGSYMGAMRLTEHGFPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSSHQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 162 RTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGVGSGVDFGRQIQEATGFE 241
Cdd:cd00763 161 RISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAGIERGKKHAIVVVAEGVYDVDELAKEIEEATGFE 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 27573984 242 TRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIAEALANKHTIDQRMYALSKELS 318
Cdd:cd00763 241 TRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGGLAVGIQNEQLVHHDIIDAIENMKPFKKDWLALAKKLS 317
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
1-319 |
0e+00 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 503.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 1 MKRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEE 80
Cdd:COG0205 1 MKRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPFKTEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 81 GQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTE-HGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATS 159
Cdd:COG0205 81 GREKALENLKKLGIDALVVIGGDGSLDGAAKLAEeYGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRDTAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 160 HERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGV--------------- 224
Cdd:COG0205 161 HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRGKGYSIIVVAEGAgdedgeavleadtda 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 225 -------GSGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIA 297
Cdd:COG0205 241 fghvrlgGIGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRGEIVLVPLE 320
|
330 340
....*....|....*....|....
gi 27573984 298 EALANKHTID--QRMYALSKELSI 319
Cdd:COG0205 321 EVANKEKPVDpdSPLIQLARELGI 344
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
3-300 |
3.90e-178 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 494.17 E-value: 3.90e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 3 RIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEGQ 82
Cdd:TIGR02482 1 KIGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRRGYKGLINGKIEPLESKNVSGIIHRGGTILGTARCPEFKTEEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 83 KKGIEQLKKHGIEGLVVIGGDGSYQGAKKLT-EHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHE 161
Cdd:TIGR02482 81 EKAVENLKKLGIEGLVVIGGDGSYTGAQKLYeEGGIPVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAVDKIRDTATSHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 162 RTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEG--VGSGVDFGRQIQEATG 239
Cdd:TIGR02482 161 RAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFDYDIDELIQRLKEQHEAGKKHSIIIVAEGniVGSAKEVAKKIEEKTG 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 27573984 240 FETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDIAEAL 300
Cdd:TIGR02482 241 IETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLEGKGGVMIGIQNNKIVTHPIEEAL 301
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-316 |
2.83e-171 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 478.33 E-value: 2.83e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 2 KRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEG 81
Cdd:cd00363 1 KKIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCKEFRTEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 82 QKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEH------GFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRD 155
Cdd:cd00363 81 RAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEwpskyqGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 156 TATSHERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADY---DMNDVIARLKRGHERGKKHSIIIVAEGV-------G 225
Cdd:cd00363 161 TASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAadeWEEEMVDVIKKRRERGKRHGIVIVAEGAidfipkpI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 226 SGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQN---NQLVDHDIAEALAN 302
Cdd:cd00363 241 TEKLLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGTPVGIQNlneNQVVRHPLTEAVNM 320
|
330
....*....|....*...
gi 27573984 303 KHT----IDQRMYALSKE 316
Cdd:cd00363 321 TKRvgvdLEGRPFKKFAK 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
3-273 |
2.50e-170 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 473.36 E-value: 2.50e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 3 RIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEEGQ 82
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 83 KKGIEQLKKHGIEGLVVIGGDGSYQGAKKLT-EHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHE 161
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSeERGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSHN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 162 RTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHeRGKKHSIIIVAEGVGSGVDFGRQIQEATGFE 241
Cdd:pfam00365 161 RVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELR-KGKRFSIIVVAEGASDGEFLAKLIEEGTGIE 239
|
250 260 270
....*....|....*....|....*....|..
gi 27573984 242 TRVTVLGHVQRGGSPTAFDRVLASRLGARAVE 273
Cdd:pfam00365 240 TRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
3-299 |
6.04e-120 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 347.75 E-value: 6.04e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 3 RIGVLTSGGDSPGMNAAIRSVVRKAIY-HGVEVYGVYHGYAGLIAGNI-KKLEVGDVGDIIHRGGTILYTARCPEFKTEE 80
Cdd:TIGR02483 1 RIGVLTGGGDCPGLNAVIRGVVRRAIAeYGWEVIGIRDGWRGLLEGDTvPLLDLEDVRGILPRGGTILGSSRTNPFKYEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 81 -GQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATS 159
Cdd:TIGR02483 81 dGDDKIVANLKELGLDALIAIGGDGTLGIARRLADKGLPVVGVPKTIDNDLEATDYTFGFDTAVEIATEALDRLHTTAES 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 160 HERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGV--------------- 224
Cdd:TIGR02483 161 HHRVMVVEVMGRHAGWIALHSGIAGGADVILIPEIPFDIDSVCEKVRERFARGKRFAIVVVAEGAkpkggemvvqegvkd 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 225 --------GSGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNNQLVDHDI 296
Cdd:TIGR02483 241 afghvrlgGIGNWLAEEIERRTGIETRATVLGHLQRGGSPSAFDRVLATRFGVAAVDLVHEGQFGHMVALRGTDIVYVPI 320
|
...
gi 27573984 297 AEA 299
Cdd:TIGR02483 321 AEA 323
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
2-317 |
3.31e-106 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 326.22 E-value: 3.31e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 2 KRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAG--NIKKLEVGDVGDIIHRGGTILYTARCPEFKTE 79
Cdd:TIGR02478 1 KRIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIREGYQGLVDGgdNIEEAQWEDVRGILSLGGTIIGTARCKEFRER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 80 EGQKKGIEQLKKHGIEGLVVIGGDGSYQGA-----------------KKLTE------HGFPCVGVPGTIDNDIPGTDFT 136
Cdd:TIGR02478 81 PGRLKAARNLVSNGIDALVVIGGDGSLTGAdlfreewpslleelvdtGKITAeqaeehRHLTIVGLVGSIDNDMCGTDMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 137 IGFDTALNTVIDAIDKIRDTATSHERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMN---DVIARLKRGHERGK 213
Cdd:TIGR02478 161 IGADSALHRICEAIDAISSTAQSHQRAFVVEVMGRHCGYLALMAAIATGADYVFIPERPPEEGwedQLCHKLKRNRKAGK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 214 KHSIIIVAEGVG-------SGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKG---GRC 283
Cdd:TIGR02478 241 RKTIVIVAEGAIdrdlnpiTSEDVKDVLVERLGLDTRITVLGHVQRGGAPSAFDRILATRQGVEAVLAVLESTPetpSPV 320
|
330 340 350
....*....|....*....|....*....|....*...
gi 27573984 284 VGIQNNQLVDHDIAEALANKHT----IDQRMYALSKEL 317
Cdd:TIGR02478 321 ISLRGNKIVRKPLVEAVAQTKTvakaIEEKDFDEAMRL 358
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
2-307 |
2.74e-93 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 281.19 E-value: 2.74e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 2 KRIGVLTSGGDSPGMNAAIRSVVRKAIYH-GVEVYGVYHGYAGLIAG--NIKKLEVGDVGDIIHRGGTILYTARCPE--- 75
Cdd:PRK14071 5 KRIGILTSGGDCAGLNAVIRAVVHRARGTyGWEVIGIRDATQGLMARppQYIELDLDQVDDLLRMGGTILGTTNKGDpfa 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 76 FKTEEGQKKG-----IEQLKKHGIEGLVVIGGDGSYQGAKKLTEHG-FPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDA 149
Cdd:PRK14071 85 FPMPDGSLRDrsqeiIDGYHSLGLDALIGIGGDGSLAILRRLAQQGgINLVGIPKTIDNDVGATEVSIGFDTAVNIATEA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 150 IDKIRDTATSHERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIARLKRGHERGKKHSIIIVAEGV----- 224
Cdd:PRK14071 165 LDRLHFTAASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTLENVCKKIRERQEEGKNFCLVVVSEAVrteeg 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 225 ---------------GSGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVGIQNN 289
Cdd:PRK14071 245 eqvtktqalgedrygGIGQYLAEQIAERTGAETRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQGKFDRMVAWQNR 324
|
330
....*....|....*...
gi 27573984 290 QLVDHDIAEALANKHTID 307
Cdd:PRK14071 325 QVVSVPIAEAIATYRAVD 342
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-278 |
3.06e-92 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 290.19 E-value: 3.06e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 2 KRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAG--NIKKLEVGDVGDIIHRGGTILYTARCPEFKTE 79
Cdd:cd00764 4 KAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKGgdYIKQAEWESVSNWLQEGGTIIGSARCKEFRER 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 80 EGQKKGIEQLKKHGIEGLVVIGGDGSYQGAK-----------------KLTEHGFP------CVGVPGTIDNDIPGTDFT 136
Cdd:cd00764 84 EGRLQAAYNLIQRGITNLCVIGGDGSLTGADlfrsewpslleelvkdgKITEEEVAkyqhlnIVGMVGSIDNDFCGTDMT 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 137 IGFDTALNTVIDAIDKIRDTATSHERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYD---MNDVIARLKRGHERGK 213
Cdd:cd00764 164 IGTDSALHRICEVVDAITTTAQSHQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERPPEdgwEDQMCRRLSEHRSRGK 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 27573984 214 KHSIIIVAEGVG-------SGVDFGRQIQEATGFETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEG 278
Cdd:cd00764 244 RLNIIIVAEGAIddqlkpiTSEDVKDLVVERLGLDTRVTTLGHVQRGGTPSAFDRILASLMGVEAVMALLEA 315
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
2-297 |
9.31e-69 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 227.61 E-value: 9.31e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 2 KRIGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTAR-CPefktEE 80
Cdd:TIGR02478 390 LRIAIIHVGAPAGGMNAATRSAVRYALARGHTVIAIHNGFSGLARHDVRELTWSDVEGWVGEGGSELGTNRsLP----GD 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 81 GQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTE--HGFPC-----VGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKI 153
Cdd:TIGR02478 466 DLGTIAYYFQQHKIDGLIIIGGFEAFEALYQLDAarEKYPAfripmVVIPATISNNVPGTEYSLGSDTALNEITEYCDNI 545
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 154 RDTAT-SHERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDV---IARLKRGHERGKKHSIIIVAEGVGSGV- 228
Cdd:TIGR02478 546 KQSASaSKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLqedIEHLKETFAEGRAGKLILRNEKASKVYt 625
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 27573984 229 -DFGRQI--QEATG-FETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELLLEGKGGrcVGIQNNQLVDHDIA 297
Cdd:TIGR02478 626 tDFIARIisEEGKGrFDARTAVLGHMQQGGSPSPFDRVRATRLAIRAVDFIEEKIKA--NKHADKLSADDTSA 696
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-275 |
1.23e-55 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 192.73 E-value: 1.23e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 4 IGVLTSGGDSPGMNAAIRSVVRKAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARcpefKTEEGQK 83
Cdd:cd00764 392 IAIVNVGAPAAGMNAAVRSAVRYGLAHGHRPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGGSELGTKR----TLPKKDL 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 84 KGI-EQLKKHGIEGLVVIGGDGSYQGAKKL-------TEHGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRD 155
Cdd:cd00764 468 ETIaYNFQKYGIDGLIIVGGFEAYKGLLQLreareqyEEFCIPMVLIPATVSNNVPGTDFSLGSDTALNALMKYCDRIKQ 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 156 TATS-HERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMNDVIA-------RLKRGHERGKKHSIIIVAEGVGSG 227
Cdd:cd00764 548 SASGtKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEEPFNIRDLQEnvehlteKMKTTIGRGLVLRNEKCNENYTTV 627
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 27573984 228 VDFGRQIQEATG-FETRVTVLGHVQRGGSPTAFDRVLASRLGARAVELL 275
Cdd:cd00764 628 FTYELYSEEGKGvFDCRTNVLGHVQQGGAPSPFDRNFGTKFAVKAMKWI 676
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
4-226 |
1.71e-44 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 157.51 E-value: 1.71e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 4 IGVLTSGGDSPGMNAAIRSVVRKAIY-HGVE-VYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKteeg 81
Cdd:PTZ00286 90 AGIVTCGGLCPGLNVVIRELVMNLINnYGVKtIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTILGSSRGGFDP---- 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 82 qKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEH----GFPC--VGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRD 155
Cdd:PTZ00286 166 -KVMVDTLIRHGINILFTLGGDGTHRGALAIYKElrrrKLNIsvVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAYV 244
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 27573984 156 TATSHER-TWVIEVMGRHAGDIALYSGLAGG-AETILIPEADYDMNDVIARLKRGHERgKKHSIIIVAEGVGS 226
Cdd:PTZ00286 245 EAKSAKNgVGIVKLMGRDSGFIALHASVASAdVNVCLIPEFDIPLEGVLEYIEQRLQK-KGHCVIVVAEGAGQ 316
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
3-292 |
1.74e-33 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 127.68 E-value: 1.74e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 3 RIGVLTSGGDSPGMNAAIRSVVRKAIYH-GV-EVYGVYHGYAGLIAG---NIKKLEVGDVGDIIHRGGTILYTARCPefk 77
Cdd:PRK06830 82 KAAIVTCGGLCPGLNDVIRAIVLELHHHyGVrRILGIRYGYQGLIPRyghDPVELTPEVVADIHEFGGTILGSSRGP--- 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 78 teegQKKG--IEQLKKHGIEGLVVIGGDGSYQGAKKLTE----HGFP--CVGVPGTIDNDIPGTDFTIGFDTALNTVIDA 149
Cdd:PRK06830 159 ----QDPEeiVDTLERMNINILFVIGGDGTLRGASAIAEeierRGLKisVIGIPKTIDNDINFIQKSFGFETAVEKATEA 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 150 IDKIRDTATSHER-TWVIEVMGRHAGDIALYSGLAGG-AETILIPEADYDM---NDVIARLKRGHERgKKHSIIIVAEGV 224
Cdd:PRK06830 235 IRCAHVEANGAPNgIGLVKLMGRHSGFIAAYAALASKdVNFVLIPEVPFDLegpNGLLAALEKRLAE-RGHAVIVVAEGA 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 225 G------------SG----VDFG----RQIQE---ATGFETRVTVL--GHVQRGGSPTAFDRVLASRLGARAVELLLEGK 279
Cdd:PRK06830 314 GqelfddtgetdaSGnpklGDIGlflkDRIKEyfkARGIPINLKYIdpSYIIRSVPANANDSVYCGFLGQNAVHAAMAGK 393
|
330
....*....|...
gi 27573984 280 GGRCVGIQNNQLV 292
Cdd:PRK06830 394 TGMVVGRWNNRFV 406
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
9-287 |
1.08e-30 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 119.58 E-value: 1.08e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 9 SGGDSPGMNAAIRSVVRKAIYHGV--EVYGVYHGYAGLIAGNI---KKLEVGDVGDIIHRGGTILYTARCPEFKTEEGQ- 82
Cdd:PRK14072 11 SGGPTAVINASAAGVIEEARKHKKigKVYGARNGIIGILDEDLidlSKESDEALAALAHTPSGALGSCRYKLKSLEEDRa 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 83 --KKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTE----HGFP--CVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKI- 153
Cdd:PRK14072 91 eyERLLEVFKAHDIGYFFYNGGNDSMDTALKVSQlakkMGYPirCIGIPKTIDNDLPGTDHCPGFGSAAKYIATSVLEAa 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 154 RDTA--TSHERTWVIEVMGRHAGDIALYSGLA-----GGAETILIPEADYDMNDVIARLKRGHERgKKHSIIIVAEGV-- 224
Cdd:PRK14072 171 LDVAamANTSKVFILEVMGRHAGWLAAAAALAkqnpdDAPHLIYLPERPFDEEKFLADVRAIVKR-YGYCVVVVSEGIrd 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 225 ---------GSGVD-FG------------RQIQEATGFETRVTVLGHVQRGG----SPTafDRVLASRLGARAVELLLEG 278
Cdd:PRK14072 250 adgkfiaeaGLAEDaFGhaqlggvapvlaNLIKEKLGKKVHWAVLDYLQRAArhiaSKT--DVEEAYAVGKAAVEYALAG 327
|
....*....
gi 27573984 279 KGGRCVGIQ 287
Cdd:PRK14072 328 KNGVMPAIR 336
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
6-225 |
1.09e-30 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 120.62 E-value: 1.09e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 6 VLTSGGDSPGMNAAIRSVVRKAIY-HGV-EVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARcpefkteEGQ- 82
Cdd:PLN02564 92 IVTCGGLCPGLNTVIREIVCGLSYmYGVtRILGIDGGYRGFYSRNTIPLTPKVVNDIHKRGGTILGTSR-------GGHd 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 83 -KKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEH----GFPC--VGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRD 155
Cdd:PLN02564 165 tSKIVDSIQDRGINQVYIIGGDGTQKGASVIYEEirrrGLKVavAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHV 244
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 27573984 156 TATSHER-TWVIEVMGRHAGDIALYSGLAG-GAETILIPEADYDMND-------VIARLKrghERGkkHSIIIVAEGVG 225
Cdd:PLN02564 245 EAESVENgIGLVKLMGRYSGFIAMYATLASrDVDCCLIPESPFYLEGkgglfefIEKRLK---ENG--HMVIVVAEGAG 318
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
5-311 |
2.35e-27 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 110.29 E-value: 2.35e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 5 GVLTSGGDSPGMNAAIRSVVRKAIYHGVE-VYGVYHGYAGLIAGNIKKLEVGD--VGDIIHRGGTILYTARCPEfKTEEG 81
Cdd:PLN02884 57 AIVTCGGLCPGLNDVIRQIVFTLEIYGVKnIVGIPFGYRGFFEKGLSEMPLSRkvVQNIHLSGGSLLGVSRGGA-KTSDI 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 82 qkkgIEQLKKHGIEGLVVIGGDGSYQGAKKLTEH------GFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRD 155
Cdd:PLN02884 136 ----VDSIEARGINMLFVLGGNGTHAGANAIHNEcrkrkmKVSVVGVPKTIDNDILLMDKTFGFDTAVEEAQRAINSAYI 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 156 TATS-HERTWVIEVMGRHAGDIALYSGLAGGAETI-LIPEADYDM---NDVIARLKRGHERgKKHSIIIVAEGVG----- 225
Cdd:PLN02884 212 EAHSaYHGIGLVKLMGRSSGFIAMHASLASGQVDIcLIPEVPFTLdgpNGVLRHLEHLIET-KGSAVVCVAEGAGqdllq 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 226 -------SG----VDFGRQIQE-------ATGFETRVTVLG--HVQRGGSPTAFDRVLASRLGARAVELLLEGKGGRCVG 285
Cdd:PLN02884 291 ktnatdaSGnpvlGDIGVHLQQeikkhfkDIGVPADVKYIDptYMIRACRANASDAILCTVLGQNAVHGAFAGFSGITVG 370
|
330 340
....*....|....*....|....*...
gi 27573984 286 IQNNQLVDHDIAEALANKHTID--QRMY 311
Cdd:PLN02884 371 ICNTHYVYLPIPEVIAYPRRVDpnSRMW 398
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
2-224 |
5.59e-21 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 93.06 E-value: 5.59e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 2 KRIGVLTSGGDSPGMNAAIRSVVR--KAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGG-TILYTARcPEFKT 78
Cdd:PRK07085 71 LKVGVILSGGQAPGGHNVIAGLFDglKKLNPDSKLFGFIGGPLGLLNGKYIEITEEVIDEYRNTGGfDMIGSGR-TKIET 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 79 EEGQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTE------HGFPCVGVPGTIDNDIPGT--DFTIGFDTALNTVIDAI 150
Cdd:PRK07085 150 EEQKEACLETVKKLKLDGLVIIGGDDSNTNAAILAEyfakhgCKTQVIGVPKTIDGDLKNEfiETSFGFDTATKTYSEMI 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 151 DKI-RDTATSHERTWVIEVMGRHAGDIALYSGLAGGAETILIPE--ADYDM--NDVIARLKRG----HERGKKHSIIIVA 221
Cdd:PRK07085 230 GNIsRDALSAKKYWHFIKLMGRSASHIALECALQTHPNICLISEevAEKKMslQDIVHYIASViadrAAKGKNYGVILIP 309
|
...
gi 27573984 222 EGV 224
Cdd:PRK07085 310 EGL 312
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
2-224 |
3.57e-19 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 88.49 E-value: 3.57e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 2 KRIGVLTSGGDSPGMNAAIRSVVR--KAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGG-TILYTARcPEFKT 78
Cdd:PTZ00468 103 RRIGVVLSGGQASGGHNVIAGLMSyiKLCNQSSQLFGFLGGPEGVYSERYRELTEDDINGILNQGGfNIICSGR-HKIET 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 79 EEGQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEH------GFPCVGVPGTIDNDIPG--TDFTIGFDTALNTVIDAI 150
Cdd:PTZ00468 182 EEQMRASLEICEKLKLHGLVVIGGDDSNTNAAVLAEYfkrnssSTVVVGCPKTIDGDLKNevIETSFGYDTAVKTYSEQI 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 151 DKIRDT-ATSHERTWVIEVMGRHAGDIALYSGLAGGAETILIPEADYDMN--------DVIARLKRGHERGKKHSIIIVA 221
Cdd:PTZ00468 262 GSIMDAiKTEGYGYYFVRLMGRSASHITLECGLQTRANMILIGEEIKEENrslmsivdEIVEMILKRDSLGKKHGIVLLP 341
|
...
gi 27573984 222 EGV 224
Cdd:PTZ00468 342 EGL 344
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-236 |
3.86e-17 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 81.84 E-value: 3.86e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 3 RIGVLTSGGDSPGMNAAIRSVVR--KAIYHGVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEE 80
Cdd:cd00765 74 KIGIVLSGGQAPGGHNVISGLFDylKERAKGSTLYGFKGGPAGILKCDYIELNAEYIQPYRNTGGFDMICSGRTKIETED 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 81 GQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEH------GFPCVGVPGTIDNDIPGTDFTI--GFDTALNTVIDAIDK 152
Cdd:cd00765 154 QFKQAEETAKKLDLDALVVIGGDDSNTNAALLAENfrskglKTRVIGVPKTIDGDLKNKEIETsfGFDTATKIYSELIGN 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 153 IRDTATSHERTW-VIEVMGRHAGDIALYSGLAGGAETILIPE------------ADYdMNDVIArlKRGhERGKKHSIII 219
Cdd:cd00765 234 VMRDARSTGKYWhFVKLMGRSASHIALECALKTHPNICIISEevsaqkqtlkniTDY-MVDVIC--KRA-ELGYNFGVVL 309
|
250
....*....|....*..
gi 27573984 220 VAEGVgsgVDFGRQIQE 236
Cdd:cd00765 310 VPEGL---IEFIPEVKE 323
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
3-224 |
3.28e-15 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 76.62 E-value: 3.28e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 3 RIGVLTSGGDSPGMNAAIRSVVRKAIYHG--VEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGG-TILYTARcpefkte 79
Cdd:PTZ00287 179 KIGIILSGGPAPGGHNVISGIYDYAKRYNeqSQVIGFLGGIDGLYSKNYVTITDSLMNRFRNLGGfNMLWSGR------- 251
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 80 eGQKKGIEQL-------KKHGIEGLVVIGGDGSYQGAKKLTEH------GFPCVGVPGTIDNDIP--GTDFTIGFDTALN 144
Cdd:PTZ00287 252 -GKVRNKDDLiaienivAKLKLNGLVIIGGDGSNSNAALISEYfaerqiPISIIGIPKTIDGDLKseAIEISFGFDTATK 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 145 TVIDAIDKI-RDTATSHERTWVIEVMGRHAGDIALYSGLAGGAETILIPEA----DYDMNDVIAR-----LKRgHERGKK 214
Cdd:PTZ00287 331 TYSEVIGNLcTDVKTGHNVYHVVRVMGRSASHVVLECALQTRPNIVLIGEEvekeNLSLKDIVSNivntiLKR-RSLNKN 409
|
250
....*....|
gi 27573984 215 HSIIIVAEGV 224
Cdd:PTZ00287 410 YGVILIPEGL 419
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
1-251 |
1.09e-14 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 73.89 E-value: 1.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 1 MKRIGVLTSGGDSPGMNAAIRSVVRK--AIYHGVEVYGVYHGYAGLIAGNikKLEVGDV----GDIIHR-GGTILYTARC 73
Cdd:PRK06555 3 VKKVALLTAGGLAPCLSSAVGGLIERytEIAPEVEIIAYRSGYQGLLLGD--SIEITPAvranAGLLHRyGGSPIGNSRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 74 PEFKTEEGQKKGI------------EQLKKHGIEGLVVIGGDGSYQGA----KKLTEHGFP--CVGVPGTIDNDIPGTDF 135
Cdd:PRK06555 81 KLTNVADCVKRGLvkegenplkvaaERLAADGVDILHTIGGDDTNTTAadlaAYLAENGYDltVVGLPKTIDNDVVPIRQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 136 TIGFDTALNTVIDAIDKIRDTATSHERTWVI-EVMGRHAGDIALYS-----------------GLAGGAETI---LIPEA 194
Cdd:PRK06555 161 SLGAWTAAEQGARFFDNVINEHSANPRMLIIhEVMGRNCGWLTAATarayrewldrqeyvpgfGLSAERWDIhavYLPEM 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 27573984 195 DYDMNDVIARLKRGHERgKKHSIIIVAEgvGSGVDFGRQIQEATGFETRVTVLGHVQ 251
Cdd:PRK06555 241 AFDLEAEAERLKAVMDE-VGNVNIFLSE--GAGLDAIVAEMEAAGEEVKRDAFGHVK 294
|
|
| PLN02251 |
PLN02251 |
pyrophosphate-dependent phosphofructokinase |
3-236 |
7.58e-13 |
|
pyrophosphate-dependent phosphofructokinase
Pssm-ID: 215140 Cd Length: 568 Bit Score: 69.05 E-value: 7.58e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 3 RIGVLTSGGDSPGMNAAIRSVVRKAIYH--GVEVYGVYHGYAGLIAGNIKKLEVGDVGDIIHRGGTILYTARCPEFKTEE 80
Cdd:PLN02251 98 KIGVVLSGGQAPGGHNVISGIFDYLQEHakGSVLYGFKGGPAGIMKCKYVELTAEFIYPYRNQGGFDMICSGRDKIETPE 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 81 GQKKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEH------GFPCVGVPGTIDNDIPGTDFTI--GFDTALNTVIDAIDK 152
Cdd:PLN02251 178 QFKQAEETATKLDLDGLVVIGGDDSNTNACLLAEYfraknlKTRVIGCPKTIDGDLKSKEVPTsfGFDTACKIYSEMIGN 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 153 IRDTATSHERTW-VIEVMGRHAGDIALYSGLAGGAETILIPE------------ADYdMNDVIArlKRGhERGKKHSIII 219
Cdd:PLN02251 258 VMIDARSTGKYYhFVRLMGRAASHITLECALQTHPNITIIGEevaakkltlknvTDY-IVDVIC--KRA-ELGYNYGVIL 333
|
250
....*....|....*..
gi 27573984 220 VAEGVgsgVDFGRQIQE 236
Cdd:PLN02251 334 IPEGL---IDFIPEVQH 347
|
|
| PLN03028 |
PLN03028 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
3-224 |
5.92e-09 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 215543 Cd Length: 610 Bit Score: 57.09 E-value: 5.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 3 RIGVLTSGGDSPGMNAAIRSVVRKAIYHGVE--VYGVYHGYAGLIAGniKKLEVGDvgDII----HRGGTILYTARCPEF 76
Cdd:PLN03028 81 RVGVVFCGRQSPGGHNVIWGLHDALKAHNPNsvLLGFLGGTEGLFAQ--KTLEITD--DVLstykNQGGYDLLGRTKDQI 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 77 KTEE---GQKKGIEQLKkhgIEGLVVIGGDGSYQGAKKLTE----HGFP--CVGVPGTIDNDI--PGTDFTIGFDTALNT 145
Cdd:PLN03028 157 RTTEqvnAALAACEALK---LDGLVIIGGVTSNTDAAQLAEtfaeAKCKtkVVGVPVTLNGDLknQFVETNVGFDTICKV 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27573984 146 VIDAIDKIRDTATSHER-TWVIEVMGRHAGDIALYSGLAGGAETILIPE----ADYDMNDVIARL-----KRGhERGKKH 215
Cdd:PLN03028 234 NSQLISNVCTDALSAEKyYYFIRLMGRKASHVALECALQSHPNMVILGEevaaSKLTLFDITKQIcdavqARA-EQDKNH 312
|
....*....
gi 27573984 216 SIIIVAEGV 224
Cdd:PLN03028 313 GVILIPEGL 321
|
|
| |
