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Conserved domains on  [gi|270047742]
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Chain A, CcdB

Protein Classification

CcdB family protein( domain architecture ID 10486789)

CcdB family protein similar to Escherichia coli type II toxin-antitoxin (TA) system toxin CcdB, the toxic component of a TA system that functions in plasmid maintenance; it is responsible for the post-segregational killing (PSK) of plasmid-free cells and its toxicity is inhibited by labile antitoxin CcdA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CcdB pfam01845
CcdB protein;
3-103 1.89e-46

CcdB protein;


:

Pssm-ID: 426470  Cd Length: 99  Bit Score: 144.22  E-value: 1.89e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270047742    3 QFTLYKNKDKSsAKTYPYFVDVQSDLLDNLNTRLVIPLTPIELLDKKaPSHLCPTIHIDEGDFIMLTQQMTSVPVKILSE 82
Cdd:pfam01845   1 QFDVYRNPGAS-AKLYPYLLDVQSDLLDDLNTRVVIPLLPLSAFPKP-PRRLNPVFEVEGESYVLMTPEMASVPARLLGK 78

                          90       100
                  ....*....|....*....|.
gi 270047742   83 PVNELSTFRNEIIAAIDFLIT 103
Cdd:pfam01845  79 PVASLSEHRDEIIAALDFLFT 99
 
Name Accession Description Interval E-value
CcdB pfam01845
CcdB protein;
3-103 1.89e-46

CcdB protein;


Pssm-ID: 426470  Cd Length: 99  Bit Score: 144.22  E-value: 1.89e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270047742    3 QFTLYKNKDKSsAKTYPYFVDVQSDLLDNLNTRLVIPLTPIELLDKKaPSHLCPTIHIDEGDFIMLTQQMTSVPVKILSE 82
Cdd:pfam01845   1 QFDVYRNPGAS-AKLYPYLLDVQSDLLDDLNTRVVIPLLPLSAFPKP-PRRLNPVFEVEGESYVLMTPEMASVPARLLGK 78

                          90       100
                  ....*....|....*....|.
gi 270047742   83 PVNELSTFRNEIIAAIDFLIT 103
Cdd:pfam01845  79 PVASLSEHRDEIIAALDFLFT 99
PRK13708 PRK13708
type II toxin-antitoxin system toxin CcdB;
3-105 8.88e-23

type II toxin-antitoxin system toxin CcdB;


Pssm-ID: 184264  Cd Length: 101  Bit Score: 84.51  E-value: 8.88e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270047742   3 QFTLYKNKDKSSaktYPYFVDVQSDLLDNLNTRLVIPLTPIELLDKKAPSHLCPTIHIDEGDFIMLTQQMTSVPVKILSE 82
Cdd:PRK13708   2 QFKVYTYKRESR---YRLFVDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESYRLMTTDMASVPVSVIGE 78

                         90       100
                 ....*....|....*....|...
gi 270047742  83 PVNELSTFRNEIIAAIDFLITGI 105
Cdd:PRK13708  79 EVADLSHRENDIKNAINLMFWGI 101
 
Name Accession Description Interval E-value
CcdB pfam01845
CcdB protein;
3-103 1.89e-46

CcdB protein;


Pssm-ID: 426470  Cd Length: 99  Bit Score: 144.22  E-value: 1.89e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270047742    3 QFTLYKNKDKSsAKTYPYFVDVQSDLLDNLNTRLVIPLTPIELLDKKaPSHLCPTIHIDEGDFIMLTQQMTSVPVKILSE 82
Cdd:pfam01845   1 QFDVYRNPGAS-AKLYPYLLDVQSDLLDDLNTRVVIPLLPLSAFPKP-PRRLNPVFEVEGESYVLMTPEMASVPARLLGK 78

                          90       100
                  ....*....|....*....|.
gi 270047742   83 PVNELSTFRNEIIAAIDFLIT 103
Cdd:pfam01845  79 PVASLSEHRDEIIAALDFLFT 99
PRK13708 PRK13708
type II toxin-antitoxin system toxin CcdB;
3-105 8.88e-23

type II toxin-antitoxin system toxin CcdB;


Pssm-ID: 184264  Cd Length: 101  Bit Score: 84.51  E-value: 8.88e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 270047742   3 QFTLYKNKDKSSaktYPYFVDVQSDLLDNLNTRLVIPLTPIELLDKKAPSHLCPTIHIDEGDFIMLTQQMTSVPVKILSE 82
Cdd:PRK13708   2 QFKVYTYKRESR---YRLFVDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESYRLMTTDMASVPVSVIGE 78

                         90       100
                 ....*....|....*....|...
gi 270047742  83 PVNELSTFRNEIIAAIDFLITGI 105
Cdd:PRK13708  79 EVADLSHRENDIKNAINLMFWGI 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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