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Conserved domains on  [gi|269849733|sp|Q8N7U7|]
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RecName: Full=Tetra-peptide repeat homeobox protein 1

Protein Classification

homeobox domain-containing protein( domain architecture ID 21)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

CATH:  1.10.10.60
Gene Ontology:  GO:0003677
PubMed:  26464018|1357790
SCOP:  4000291

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Homeodomain super family cl47488
Homeodomain;
1-25 3.04e-04

Homeodomain;


The actual alignment was detected with superfamily member pfam00046:

Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 38.64  E-value: 3.04e-04
                          10        20
                  ....*....|....*....|....*
gi 269849733    1 MLSLREQQLQVWFKNRRAKlarERR 25
Cdd:pfam00046  36 QLGLTERQVKVWFQNRRAK---WKR 57
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
1-25 3.04e-04

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 38.64  E-value: 3.04e-04
                          10        20
                  ....*....|....*....|....*
gi 269849733    1 MLSLREQQLQVWFKNRRAKlarERR 25
Cdd:pfam00046  36 QLGLTERQVKVWFQNRRAK---WKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 2-19 8.01e-04

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 37.23  E-value: 8.01e-04
                           10
                   ....*....|....*...
gi 269849733     2 LSLREQQLQVWFKNRRAK 19
Cdd:smart00389  38 LGLSERQVKVWFQNRRAK 55
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 2-24 2.05e-03

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 36.07  E-value: 2.05e-03
                         10        20
                 ....*....|....*....|...
gi 269849733   2 LSLREQQLQVWFKNRRAKLARER 24
Cdd:cd00086   37 LGLTERQVKIWFQNRRAKLKRSE 59
 
Name Accession Description Interval E-value
Homeodomain pfam00046
Homeodomain;
1-25 3.04e-04

Homeodomain;


Pssm-ID: 459649 [Multi-domain]  Cd Length: 57  Bit Score: 38.64  E-value: 3.04e-04
                          10        20
                  ....*....|....*....|....*
gi 269849733    1 MLSLREQQLQVWFKNRRAKlarERR 25
Cdd:pfam00046  36 QLGLTERQVKVWFQNRRAK---WKR 57
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 2-19 8.01e-04

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 37.23  E-value: 8.01e-04
                           10
                   ....*....|....*...
gi 269849733     2 LSLREQQLQVWFKNRRAK 19
Cdd:smart00389  38 LGLSERQVKVWFQNRRAK 55
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 2-24 2.05e-03

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 36.07  E-value: 2.05e-03
                         10        20
                 ....*....|....*....|...
gi 269849733   2 LSLREQQLQVWFKNRRAKLARER 24
Cdd:cd00086   37 LGLTERQVKIWFQNRRAKLKRSE 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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