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Conserved domains on  [gi|268325348|emb|CBH38936|]
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hypothetical protein, flavin containing amine oxidoreductase family [uncultured archaeon]

Protein Classification

phytoene desaturase family protein( domain architecture ID 11440907)

phytoene desaturase family protein is an NAD(P)/FAD-dependent oxidoreductase that catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; similar to phytoene desaturase, which converts phytoene into 3,4-didehydrolycopene via several intermediates by introducing up to five double bonds into phytoene

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
21-468 5.46e-34

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 133.44  E-value: 5.46e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  21 LTTGALLTRQGYNVEIFEKEPIVGGRAlslngnaltfetynnvlSQFHMNipfsepnmetifdkkmlaGYTLDLGFHTIG 100
Cdd:COG1233   16 LAAAALLARAGYRVTVLEKNDTPGGRA-----------------RTFERP------------------GFRFDVGPSVLT 60
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 101 ggVGSNLERVLSEFGepvemLESKVGLIKNSDFDFPFLSTGDKIKI---LPRILQLL--FSGEST---------MRKLDD 166
Cdd:COG1233   61 --MPGVLERLFRELG-----LEDYLELVPLDPAYRVPFPDGRALDLprdLERTAAELerLFPGDAeayrrflaeLRRLYD 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 167 IPMTETINKYGKS-----KMKLILEIFSRAITTVNN-LDRISTGDAFRA----QkNLLNGSKP----------------- 219
Cdd:COG1233  134 ALLEDLLYRPLLSlrdllRPLALARLLRLLLRSLRDlLRRYFKDPRLRAllagQ-ALYLGLSPdrtpalyaliayleyag 212
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 220 -VGYPRHGLQRVSQTLAHIVKRYGGEIHLNHPVDKIIIDNNKIVGVVVGD-EEHFFKTVITNIPVQNLFF-IADEKHFPT 296
Cdd:COG1233  213 gVWYPKGGMGALADALARLAEELGGEIRTGAEVERILVEGGRATGVRLADgEEIRADAVVSNADPAHTYLrLLGEEALPA 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 297 EYVRTLKTLT-GTGSLCAYYSLNKIDPQLLGKSFLFIERNAGLAGNDAVGMID----FMAALP---ESGLAPTSHQLVQA 368
Cdd:COG1233  293 RYRRRLERFRySPSAFKLYLGLDGPLPGLAHHTIHLSEDYEAAFDDIFRGRLPedpsLYVSIPsltDPSLAPEGKHTLWV 372
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 369 YIICSPD--EAQSGKKLDELKNMLDTnLENLMPAFRSHLQWS-IYPAVWHLD----------GVAKTIDNK---KPEIQ- 431
Cdd:COG1233  373 LVPVPYGleDAWDELKEEYAERILAR-LERYAPGLRDRIVAReVLTPLDFERylnlvggaiyGGAHTLDQSaffRPSNYr 451
                        490       500       510
                 ....*....|....*....|....*....|....*...
gi 268325348 432 TPIDNLYLVGDCVkSPDIGINCAINSAKTL-QAILARE 468
Cdd:COG1233  452 TPIPGLYLVGAST-HPGGGVPGVLISGRLAaRRILKDL 488
 
Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
21-468 5.46e-34

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 133.44  E-value: 5.46e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  21 LTTGALLTRQGYNVEIFEKEPIVGGRAlslngnaltfetynnvlSQFHMNipfsepnmetifdkkmlaGYTLDLGFHTIG 100
Cdd:COG1233   16 LAAAALLARAGYRVTVLEKNDTPGGRA-----------------RTFERP------------------GFRFDVGPSVLT 60
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 101 ggVGSNLERVLSEFGepvemLESKVGLIKNSDFDFPFLSTGDKIKI---LPRILQLL--FSGEST---------MRKLDD 166
Cdd:COG1233   61 --MPGVLERLFRELG-----LEDYLELVPLDPAYRVPFPDGRALDLprdLERTAAELerLFPGDAeayrrflaeLRRLYD 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 167 IPMTETINKYGKS-----KMKLILEIFSRAITTVNN-LDRISTGDAFRA----QkNLLNGSKP----------------- 219
Cdd:COG1233  134 ALLEDLLYRPLLSlrdllRPLALARLLRLLLRSLRDlLRRYFKDPRLRAllagQ-ALYLGLSPdrtpalyaliayleyag 212
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 220 -VGYPRHGLQRVSQTLAHIVKRYGGEIHLNHPVDKIIIDNNKIVGVVVGD-EEHFFKTVITNIPVQNLFF-IADEKHFPT 296
Cdd:COG1233  213 gVWYPKGGMGALADALARLAEELGGEIRTGAEVERILVEGGRATGVRLADgEEIRADAVVSNADPAHTYLrLLGEEALPA 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 297 EYVRTLKTLT-GTGSLCAYYSLNKIDPQLLGKSFLFIERNAGLAGNDAVGMID----FMAALP---ESGLAPTSHQLVQA 368
Cdd:COG1233  293 RYRRRLERFRySPSAFKLYLGLDGPLPGLAHHTIHLSEDYEAAFDDIFRGRLPedpsLYVSIPsltDPSLAPEGKHTLWV 372
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 369 YIICSPD--EAQSGKKLDELKNMLDTnLENLMPAFRSHLQWS-IYPAVWHLD----------GVAKTIDNK---KPEIQ- 431
Cdd:COG1233  373 LVPVPYGleDAWDELKEEYAERILAR-LERYAPGLRDRIVAReVLTPLDFERylnlvggaiyGGAHTLDQSaffRPSNYr 451
                        490       500       510
                 ....*....|....*....|....*....|....*...
gi 268325348 432 TPIDNLYLVGDCVkSPDIGINCAINSAKTL-QAILARE 468
Cdd:COG1233  452 TPIPGLYLVGAST-HPGGGVPGVLISGRLAaRRILKDL 488
PRK07233 PRK07233
hypothetical protein; Provisional
21-468 2.65e-15

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 77.62  E-value: 2.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  21 LTTGALLTRQGYNVEIFEKEPIVGGRALSLNGNALTFETYnnvlsqFHmnipFSEPNMETIFDkkMLAgytlDLGF-HTI 99
Cdd:PRK07233  12 LAAAYRLAKRGHEVTVFEADDQLGGLAASFEFGGLPIERF------YH----HIFKSDEALLE--LLD----ELGLeDKL 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 100 GGGVGSN---LERVLSEFGEPVEMLEskvgliknsdfdFPFLSTGDKIkilpRILQLLFSGESTM--RKLDDIPMTETIN 174
Cdd:PRK07233  76 RWRETKTgyyVDGKLYPLGTPLELLR------------FPHLSLIDKF----RLGLLTLLARRIKdwRALDKVPAEEWLR 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 175 K-YGKSK-----MKLILEIFSRAITTVNN---LDRIstgdAFRAQKNLLNGSKPVGYPRHGLQRVSQTLAHIVKRYGGEI 245
Cdd:PRK07233 140 RwSGEGVyevfwEPLLESKFGDYADDVSAawlWSRI----KRRGNRRYSLFGEKLGYLEGGFATLIDALAEAIEARGGEI 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 246 HLNHPVDKIIIDNNKIVGVVVGDEEHFFKTVITNIPVQnlfFIAD-EKHFPTEYVRTLKTLTGTGSLCA----------Y 314
Cdd:PRK07233 216 RLGTPVTSVVIDGGGVTGVEVDGEEEDFDAVISTAPPP---ILARlVPDLPADVLARLRRIDYQGVVCMvlklrrpltdY 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 315 YSLNKIDPQllgksflfiernaglagndavgmIDFMAALPESGLAPTSHQL------VQAYIicsPDEaqsgkklDELKN 388
Cdd:PRK07233 293 YWLNINDPG-----------------------APFGGVIEHTNLVPPERYGgehlvyLPKYL---PGD-------HPLWQ 339
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 389 MLDTNLENLmpaFRSHLQwSIYPAV---WHLD---------------GVAKTIdnkkPEIQTPIDNLYLVGDC-VKSPDI 449
Cdd:PRK07233 340 MSDEELLDR---FLSYLR-KMFPDFdrdDVRAvrisrapyaqpiyepGYLDKI----PPYDTPIEGLYLAGMSqIYPEDR 411
                        490
                 ....*....|....*....
gi 268325348 450 GINCAINSAKTLQAILARE 468
Cdd:PRK07233 412 SINGSVRAGRRVAREILED 430
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
21-442 2.30e-14

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 74.83  E-value: 2.30e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348   21 LTTGALLTRQGYNVEIFEKEPIVGGRALSlngnaltfetynnvlsqfhmnipfsepnmetifdkKMLAGYTLDLGFHTIG 100
Cdd:pfam01593   4 LAAARELLRAGHDVTVLEARDRVGGRIRT-----------------------------------VRDDGFLIELGAMWFH 48
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  101 GG----------VGSNLERVLSEFGEPVEMLeSKVGLIKNSDFDF------PFLSTGDKIKI---LPRILQLLFSGESTM 161
Cdd:pfam01593  49 GAqppllallkeLGLEDRLVLPDPAPFYTVL-FAGGRRYPGDFRRvpagweGLLEFGRLLSIpekLRLGLAALASDALDE 127
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  162 RKLDDIPMTETINKYGK--------------SKMKLILEIFSRAITTvnNLDRISTGDAFRAQKNLLNGSKPVGYPRHGL 227
Cdd:pfam01593 128 FDLDDFSLAESLLFLGRrgpgdvevwdrlidPELFAALPFASGAFAG--DPSELSAGLALPLLWALLGEGGSLLLPRGGL 205
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  228 QRVSQTLAhiVKRYGGEIHLNHPVDKIIIDNNKiVGVVVGDEEHF-FKTVITNIPVQNLFFIADEKHFPTEYVRTLKTLT 306
Cdd:pfam01593 206 GALPDALA--AQLLGGDVRLNTRVRSIDREGDG-VTVTLTDGEVIeADAVIVTVPLGVLKRILFTPPLPPEKARAIRNLG 282
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  307 GTGSLCAYYSLnkiDPQLLGKSFLFIERNAGLagNDAVGMIDFMAAlpeSGLAPTSHQLV-QAYIICSPDEAQSGKKLD- 384
Cdd:pfam01593 283 YGPVNKVHLEF---DRKFWPDLGLLGLLSELL--TGLGTAFSWLTF---PNRAPPGKGLLlLVYVGPGDRARELEGLSDe 354
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 268325348  385 ELKNMLDTNLENLMPAFRSHLQWSIYPaVWHLDGVAKTI----------DNKKPEIQTPIDNLYLVGD 442
Cdd:pfam01593 355 ELLQAVLRDLRKLFGEEAPEPLRVLVS-DWHTDPWPRGSyslpqygpghDDYRPLARTPDPGLFFAGE 421
 
Name Accession Description Interval E-value
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
21-468 5.46e-34

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 133.44  E-value: 5.46e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  21 LTTGALLTRQGYNVEIFEKEPIVGGRAlslngnaltfetynnvlSQFHMNipfsepnmetifdkkmlaGYTLDLGFHTIG 100
Cdd:COG1233   16 LAAAALLARAGYRVTVLEKNDTPGGRA-----------------RTFERP------------------GFRFDVGPSVLT 60
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 101 ggVGSNLERVLSEFGepvemLESKVGLIKNSDFDFPFLSTGDKIKI---LPRILQLL--FSGEST---------MRKLDD 166
Cdd:COG1233   61 --MPGVLERLFRELG-----LEDYLELVPLDPAYRVPFPDGRALDLprdLERTAAELerLFPGDAeayrrflaeLRRLYD 133
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 167 IPMTETINKYGKS-----KMKLILEIFSRAITTVNN-LDRISTGDAFRA----QkNLLNGSKP----------------- 219
Cdd:COG1233  134 ALLEDLLYRPLLSlrdllRPLALARLLRLLLRSLRDlLRRYFKDPRLRAllagQ-ALYLGLSPdrtpalyaliayleyag 212
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 220 -VGYPRHGLQRVSQTLAHIVKRYGGEIHLNHPVDKIIIDNNKIVGVVVGD-EEHFFKTVITNIPVQNLFF-IADEKHFPT 296
Cdd:COG1233  213 gVWYPKGGMGALADALARLAEELGGEIRTGAEVERILVEGGRATGVRLADgEEIRADAVVSNADPAHTYLrLLGEEALPA 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 297 EYVRTLKTLT-GTGSLCAYYSLNKIDPQLLGKSFLFIERNAGLAGNDAVGMID----FMAALP---ESGLAPTSHQLVQA 368
Cdd:COG1233  293 RYRRRLERFRySPSAFKLYLGLDGPLPGLAHHTIHLSEDYEAAFDDIFRGRLPedpsLYVSIPsltDPSLAPEGKHTLWV 372
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 369 YIICSPD--EAQSGKKLDELKNMLDTnLENLMPAFRSHLQWS-IYPAVWHLD----------GVAKTIDNK---KPEIQ- 431
Cdd:COG1233  373 LVPVPYGleDAWDELKEEYAERILAR-LERYAPGLRDRIVAReVLTPLDFERylnlvggaiyGGAHTLDQSaffRPSNYr 451
                        490       500       510
                 ....*....|....*....|....*....|....*...
gi 268325348 432 TPIDNLYLVGDCVkSPDIGINCAINSAKTL-QAILARE 468
Cdd:COG1233  452 TPIPGLYLVGAST-HPGGGVPGVLISGRLAaRRILKDL 488
PRK07233 PRK07233
hypothetical protein; Provisional
21-468 2.65e-15

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 77.62  E-value: 2.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  21 LTTGALLTRQGYNVEIFEKEPIVGGRALSLNGNALTFETYnnvlsqFHmnipFSEPNMETIFDkkMLAgytlDLGF-HTI 99
Cdd:PRK07233  12 LAAAYRLAKRGHEVTVFEADDQLGGLAASFEFGGLPIERF------YH----HIFKSDEALLE--LLD----ELGLeDKL 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 100 GGGVGSN---LERVLSEFGEPVEMLEskvgliknsdfdFPFLSTGDKIkilpRILQLLFSGESTM--RKLDDIPMTETIN 174
Cdd:PRK07233  76 RWRETKTgyyVDGKLYPLGTPLELLR------------FPHLSLIDKF----RLGLLTLLARRIKdwRALDKVPAEEWLR 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 175 K-YGKSK-----MKLILEIFSRAITTVNN---LDRIstgdAFRAQKNLLNGSKPVGYPRHGLQRVSQTLAHIVKRYGGEI 245
Cdd:PRK07233 140 RwSGEGVyevfwEPLLESKFGDYADDVSAawlWSRI----KRRGNRRYSLFGEKLGYLEGGFATLIDALAEAIEARGGEI 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 246 HLNHPVDKIIIDNNKIVGVVVGDEEHFFKTVITNIPVQnlfFIAD-EKHFPTEYVRTLKTLTGTGSLCA----------Y 314
Cdd:PRK07233 216 RLGTPVTSVVIDGGGVTGVEVDGEEEDFDAVISTAPPP---ILARlVPDLPADVLARLRRIDYQGVVCMvlklrrpltdY 292
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 315 YSLNKIDPQllgksflfiernaglagndavgmIDFMAALPESGLAPTSHQL------VQAYIicsPDEaqsgkklDELKN 388
Cdd:PRK07233 293 YWLNINDPG-----------------------APFGGVIEHTNLVPPERYGgehlvyLPKYL---PGD-------HPLWQ 339
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 389 MLDTNLENLmpaFRSHLQwSIYPAV---WHLD---------------GVAKTIdnkkPEIQTPIDNLYLVGDC-VKSPDI 449
Cdd:PRK07233 340 MSDEELLDR---FLSYLR-KMFPDFdrdDVRAvrisrapyaqpiyepGYLDKI----PPYDTPIEGLYLAGMSqIYPEDR 411
                        490
                 ....*....|....*....
gi 268325348 450 GINCAINSAKTLQAILARE 468
Cdd:PRK07233 412 SINGSVRAGRRVAREILED 430
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
21-442 2.30e-14

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 74.83  E-value: 2.30e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348   21 LTTGALLTRQGYNVEIFEKEPIVGGRALSlngnaltfetynnvlsqfhmnipfsepnmetifdkKMLAGYTLDLGFHTIG 100
Cdd:pfam01593   4 LAAARELLRAGHDVTVLEARDRVGGRIRT-----------------------------------VRDDGFLIELGAMWFH 48
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  101 GG----------VGSNLERVLSEFGEPVEMLeSKVGLIKNSDFDF------PFLSTGDKIKI---LPRILQLLFSGESTM 161
Cdd:pfam01593  49 GAqppllallkeLGLEDRLVLPDPAPFYTVL-FAGGRRYPGDFRRvpagweGLLEFGRLLSIpekLRLGLAALASDALDE 127
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  162 RKLDDIPMTETINKYGK--------------SKMKLILEIFSRAITTvnNLDRISTGDAFRAQKNLLNGSKPVGYPRHGL 227
Cdd:pfam01593 128 FDLDDFSLAESLLFLGRrgpgdvevwdrlidPELFAALPFASGAFAG--DPSELSAGLALPLLWALLGEGGSLLLPRGGL 205
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  228 QRVSQTLAhiVKRYGGEIHLNHPVDKIIIDNNKiVGVVVGDEEHF-FKTVITNIPVQNLFFIADEKHFPTEYVRTLKTLT 306
Cdd:pfam01593 206 GALPDALA--AQLLGGDVRLNTRVRSIDREGDG-VTVTLTDGEVIeADAVIVTVPLGVLKRILFTPPLPPEKARAIRNLG 282
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  307 GTGSLCAYYSLnkiDPQLLGKSFLFIERNAGLagNDAVGMIDFMAAlpeSGLAPTSHQLV-QAYIICSPDEAQSGKKLD- 384
Cdd:pfam01593 283 YGPVNKVHLEF---DRKFWPDLGLLGLLSELL--TGLGTAFSWLTF---PNRAPPGKGLLlLVYVGPGDRARELEGLSDe 354
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 268325348  385 ELKNMLDTNLENLMPAFRSHLQWSIYPaVWHLDGVAKTI----------DNKKPEIQTPIDNLYLVGD 442
Cdd:pfam01593 355 ELLQAVLRDLRKLFGEEAPEPLRVLVS-DWHTDPWPRGSyslpqygpghDDYRPLARTPDPGLFFAGE 421
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
19-442 1.12e-09

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 60.25  E-value: 1.12e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  19 GGLTTGALLTRQGYNVEIFEKEPIVGGRALSL----------NGNALTFETYNNVLSQfhmnipfsepnMETIFDKKMLA 88
Cdd:COG3349   14 AGLAAAVELAEAGFRVTLLEARPRLGGRARSFpdpdtglpidNGQHVLLGCYRNTLDL-----------LRRIGAADNLV 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  89 GyTLDLGFHTIGGGVGSnLERvlSEFGEPVEMLeskVGLiknsdFDFPFLSTGDKIkilpRILQLLFSG-ESTMRKLDDI 167
Cdd:COG3349   83 G-PEPLQFPLPGGRRWT-LRA--PRLPAPLHLL---RAL-----LRAPGLSLADRL----ALLRLLTACrERRWRELDDI 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 168 PMTETINKYGKSKM--KLILEIFSRAitTVN-NLDRISTGdAFRA--QKNLLNGSKP--VGYPRHGLQR--VSQTLAHIV 238
Cdd:COG3349  147 SVADWLRRHGQSPRliRRLWEPLLLA--ALNtPPEQASAR-LALTvlRETLLAGPAAsdLLVPRGPLSElfVDPALAYLE 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 239 KRyGGEIHLNHPVDKIIIDNNKIVGVVVGDEEHF-FKTVITNIPVQNLffiadekhfpteyVRTLKTLTgtgslcAYYSL 317
Cdd:COG3349  224 AR-GGEVRLGTRVRALEFDGGRVTGLVLADGETVpADAVVLAVPPEVA-------------ARLLPELA------RLPEL 283
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 318 NKIDPqlLGKS-----FLFIERNAGLAGNDAVGMI--------DFMAALPESGlaptshQLVQAYIicSPDEAQSGKKLD 384
Cdd:COG3349  284 GLLAP--LEYSpivnvHLWLDRPVTLGPPPFAGLVgstsqwvfDRGAGDGGQG------GVLSVVI--SAADRLLDLSRE 353
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 268325348 385 ELKNMLDTNLENLMPAFRSHlqwsiyPAVWHldgvaKTIDNKK-------------PEIQTPIDNLYLVGD 442
Cdd:COG3349  354 ELAAEVWAELAALLPAAREA------LPVWS-----RVVREKRatfaatpgsdrlrPGARTPIPNLFLAGD 413
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
21-319 1.39e-09

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 59.85  E-value: 1.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  21 LTTGALLTRQGYNVEIFEKEPIVGGRALSLNGNALTFETYnnvlsqfhmnipfsePNmeTIFDKKmlaGYTLDLgFHTIG 100
Cdd:COG1232   14 LTAAYRLAKAGHEVTVLEASDRVGGLIRTVEVDGFRIDRG---------------PH--SFLTRD---PEVLEL-LRELG 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 101 ggVGSNLE-------RVLSEfGEPVEMLESKVGLIKnsdfdFPFLSTGDKIkilpRILQLLFSGesTMRKLDDIPMTE-T 172
Cdd:COG1232   73 --LGDELVwpntrksYIYYG-GKLHPLPQGPLALLR-----SPLLSLAGKL----RALLELLAP--RRPPGEDESLAEfV 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 173 INKYGKskmklilEIFSRAITTVN------NLDRIST--------------GDAFRAQKNLLNGSKP---VGYPRHGLQR 229
Cdd:COG1232  139 RRRFGR-------EVYERLVEPLLegvyagDPDELSAdwafprlkrlelehGSLIKGALALRKGAKAgevFGYLRGGLGT 211
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 230 VSQTLAHIVKRygGEIHLNHPVDKIIIDNNKiVGVVVGD-EEHFFKTVITNIPVQ---NLFfiadeKHFPTEYVRTLKTL 305
Cdd:COG1232  212 LVEALAEALEA--GEIRLGTRVTAIEREGGG-WRVTTSDgETIEADAVVSATPAPalaRLL-----APLPPEVAAALAGI 283
                        330
                 ....*....|....
gi 268325348 306 TGTGSLCAYYSLNK 319
Cdd:COG1232  284 PYASVAVVALGFDR 297
GDI pfam00996
GDP dissociation inhibitor;
216-277 1.28e-05

GDP dissociation inhibitor;


Pssm-ID: 395792  Cd Length: 436  Bit Score: 47.42  E-value: 1.28e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 268325348  216 GSKPVGYPRHGLQRVSQTLAHIVKRYGGEIHLNHPVDKIII-DNNKIVGVVVGDEEHFFKTVI 277
Cdd:pfam00996 219 GKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPVDEVVYdEDGKVVGVKSGGEVAKCKQVI 281
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
232-277 4.63e-05

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 45.59  E-value: 4.63e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 268325348 232 QTLAHIVKRYGGEIHLNHPVDKIIIDNNKIVGVVV---GDEEHFF--KTVI 277
Cdd:COG1053  138 ATLYQAALRLGVEIFTETEVLDLIVDDGRVVGVVArdrTGEIVRIraKAVV 188
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
19-114 4.26e-04

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 38.67  E-value: 4.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348   19 GGLTTGALLTRQGYNVEIFEKEPIVGGRALSLNgnaltfetynnvlsqfhmnipfsepnmetifdkkmLAGYTLDLGFHT 98
Cdd:pfam13450   7 AGLVAAALLAKRGFRVLVLEKRDRLGGNAYSYR-----------------------------------VPGYVFDYGAHI 51
                          90
                  ....*....|....*.
gi 268325348   99 IGGGVGSNLERVLSEF 114
Cdd:pfam13450  52 FHGSDEPNVRDLLDEL 67
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
19-281 5.08e-03

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 39.13  E-value: 5.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  19 GGLTTGALLTRQGYNVEIFEKEPIVGGRALSlngnaltfetynnvlsqfhmnipfsepnmetifDKKMLAGYTLDLGFHT 98
Cdd:COG1231   18 AGLAAARELRKAGLDVTVLEARDRVGGRVWT---------------------------------LRFGDDGLYAELGAMR 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348  99 IGGGvGSNLERVLSEFGEPVEMLESKVG---------LIKNSDFDFPFLSTGDKI-KILPRILQLLFSGESTMRKLDDIP 168
Cdd:COG1231   65 IPPS-HTNLLALARELGLPLEPFPNENGnallylggkRVRAGEIAADLRGVAELLaKLLRALAAALDPWAHPAAELDRES 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 268325348 169 MTETINKYGKSK-MKLILEIFSRAITTVnNLDRISTGDAFRAQKNLLNGSK---PVGyprhGLQRVSQTLAhivKRYGGE 244
Cdd:COG1231  144 LAEWLRRNGASPsARRLLGLLGAGEYGA-DPDELSLLDLLRYAASAGGGAQqfrIVG----GMDQLPRALA---AELGDR 215
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 268325348 245 IHLNHPVDKIIIDNNkivGVVV---GDEEHFFKTVITNIP 281
Cdd:COG1231  216 IRLGAPVTRIRQDGD---GVTVttdDGGTVRADAVIVTVP 252
PTZ00363 PTZ00363
rab-GDP dissociation inhibitor; Provisional
216-277 7.85e-03

rab-GDP dissociation inhibitor; Provisional


Pssm-ID: 185577  Cd Length: 443  Bit Score: 38.43  E-value: 7.85e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 268325348 216 GSKPVGYPRHGLQRVSQTLAHIVKRYGGEIHLNHPVDKIIIDNN-KIVGVV-VGDEEHFFKTVI 277
Cdd:PTZ00363 220 GKSPFIYPLYGLGGLPQAFSRLCAIYGGTYMLNTPVDEVVFDENgKVCGVKsEGGEVAKCKLVI 283
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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