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Conserved domains on  [gi|266334|sp|Q01042|]
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RecName: Full=Transcriptional regulator ICP22 homolog; AltName: Full=Immediate-early protein

Protein Classification

ICP22 family protein( domain architecture ID 708738)

ICP22 family protein similar to Herpesvirus saimiri transcriptional regulator ICP22 homolog (also known as immediate-early protein) that regulates the transcription of alphaherpesviruses and their host genes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03169 super family cl27451
hypothetical protein; Provisional
 1-407 4.80e-107

hypothetical protein; Provisional


The actual alignment was detected with superfamily member PHA03169:

Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 321.53  E-value: 4.80e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334      1 MAPRRRKAKRRRHTLRSECKDKCKCHVQCYVSPRKR----RRKLKPQGDDDINTTHQQQAALTEEQRREEVEEEGEERER 76
Cdd:PHA03169   1 MSRQRRKAKRSRHTLRSSCRGHCKRHGGTREQAGRRrgtaARAAKPAPPAPTTSGPQVRAVAEQGHRQTESDTETAEESR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334     77 RGEEEREGEGGEEGEGREEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEE 156
Cdd:PHA03169  81 HGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334    157 EAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEEAEEEAEEAEE 236
Cdd:PHA03169 161 QQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334    237 EEEEAGPSTPRLPHYKVVGQKPSTQPGGVPKLCLKM--QPQHRSRLPKGKQSHDKVPKKYQARNKFFSQAAPSVLDLSPK 314
Cdd:PHA03169 241 EREGPPFPGHRSHSYTVVGWKPSTRPGGVPKLCLRCtsHPSHRSRLPEGQQSEDKVPRKYQARRRFFRQVLPSILPPRPG 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334    315 SWCWVVDFWGPTDALYRLSRSLSFPGAVSSGIQTFPKGPHATGPWVYFITVYCRTFQTAKEVIKAQKKYEKKYPRSAKLK 394
Cdd:PHA03169 321 PWCWVVFCWGDPYSLYRLSRCLQFPGAVSSGVQTFPDAPGSPVIWAYCITVFCQSRGTAKAVIKAQKKYEKKYPRSAHLK 400

                        410
                 ....*....|...
gi 266334    395 ASLGKFSKSLPIE 407
Cdd:PHA03169 401 ASLVRMSRGLPIQ 413
 
Name Accession Description Interval E-value
PHA03169 PHA03169
hypothetical protein; Provisional
 1-407 4.80e-107

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 321.53  E-value: 4.80e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334      1 MAPRRRKAKRRRHTLRSECKDKCKCHVQCYVSPRKR----RRKLKPQGDDDINTTHQQQAALTEEQRREEVEEEGEERER 76
Cdd:PHA03169   1 MSRQRRKAKRSRHTLRSSCRGHCKRHGGTREQAGRRrgtaARAAKPAPPAPTTSGPQVRAVAEQGHRQTESDTETAEESR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334     77 RGEEEREGEGGEEGEGREEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEE 156
Cdd:PHA03169  81 HGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334    157 EAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEEAEEEAEEAEE 236
Cdd:PHA03169 161 QQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334    237 EEEEAGPSTPRLPHYKVVGQKPSTQPGGVPKLCLKM--QPQHRSRLPKGKQSHDKVPKKYQARNKFFSQAAPSVLDLSPK 314
Cdd:PHA03169 241 EREGPPFPGHRSHSYTVVGWKPSTRPGGVPKLCLRCtsHPSHRSRLPEGQQSEDKVPRKYQARRRFFRQVLPSILPPRPG 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334    315 SWCWVVDFWGPTDALYRLSRSLSFPGAVSSGIQTFPKGPHATGPWVYFITVYCRTFQTAKEVIKAQKKYEKKYPRSAKLK 394
Cdd:PHA03169 321 PWCWVVFCWGDPYSLYRLSRCLQFPGAVSSGVQTFPDAPGSPVIWAYCITVFCQSRGTAKAVIKAQKKYEKKYPRSAHLK 400

                        410
                 ....*....|...
gi 266334    395 ASLGKFSKSLPIE 407
Cdd:PHA03169 401 ASLVRMSRGLPIQ 413
 
Name Accession Description Interval E-value
PHA03169 PHA03169
hypothetical protein; Provisional
 1-407 4.80e-107

hypothetical protein; Provisional


Pssm-ID: 223003 [Multi-domain]  Cd Length: 413  Bit Score: 321.53  E-value: 4.80e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334      1 MAPRRRKAKRRRHTLRSECKDKCKCHVQCYVSPRKR----RRKLKPQGDDDINTTHQQQAALTEEQRREEVEEEGEERER 76
Cdd:PHA03169   1 MSRQRRKAKRSRHTLRSSCRGHCKRHGGTREQAGRRrgtaARAAKPAPPAPTTSGPQVRAVAEQGHRQTESDTETAEESR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334     77 RGEEEREGEGGEEGEGREEAEEEEAEEKEAEEEEAEEAEEEAEEEEAEEAEAEEEEAEEEEAEEEEAEEAEEEEAEEAEE 156
Cdd:PHA03169  81 HGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPASHSPPPSPPSHPGPHEPAPPESHNPSPN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334    157 EAEEEEAEEEAEEEAEEAEEAEEEAEEEAEEAEEAEEAEEAEEEAEEAEEEAEEAEEEAEEAEEAEEAEEAEEEAEEAEE 236
Cdd:PHA03169 161 QQPSSFLQPSHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTEP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334    237 EEEEAGPSTPRLPHYKVVGQKPSTQPGGVPKLCLKM--QPQHRSRLPKGKQSHDKVPKKYQARNKFFSQAAPSVLDLSPK 314
Cdd:PHA03169 241 EREGPPFPGHRSHSYTVVGWKPSTRPGGVPKLCLRCtsHPSHRSRLPEGQQSEDKVPRKYQARRRFFRQVLPSILPPRPG 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 266334    315 SWCWVVDFWGPTDALYRLSRSLSFPGAVSSGIQTFPKGPHATGPWVYFITVYCRTFQTAKEVIKAQKKYEKKYPRSAKLK 394
Cdd:PHA03169 321 PWCWVVFCWGDPYSLYRLSRCLQFPGAVSSGVQTFPDAPGSPVIWAYCITVFCQSRGTAKAVIKAQKKYEKKYPRSAHLK 400

                        410
                 ....*....|...
gi 266334    395 ASLGKFSKSLPIE 407
Cdd:PHA03169 401 ASLVRMSRGLPIQ 413
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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