|
Name |
Accession |
Description |
Interval |
E-value |
| MAGE |
pfam01454 |
MAGE homology domain; The MAGE (melanoma antigen-encoding gene) family are expressed in a wide ... |
1027-1195 |
1.22e-26 |
|
MAGE homology domain; The MAGE (melanoma antigen-encoding gene) family are expressed in a wide variety of tumours but not in normal cells, with the exception of the male germ cells, placenta, and, possibly, cells of the developing embryo. The cellular function of this family is unknown. This family also contains the yeast protein, Nse3. The Nse3 protein is part of the Smc5-6 complex. Nse3 has been demonstrated to be important for meiosis.
Pssm-ID: 426270 Cd Length: 205 Bit Score: 108.90 E-value: 1.22e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 1027 LVQFLLVKDQAKVPVQRSEMVKVILREY-KDECLDIINRANNKLECAFGYQLKEIDTKNHA------------------- 1086
Cdd:pfam01454 1 LVRYALACEYQRTPIRREDISKKVLGENrKRLFKKVFEEAQKILRDVFGMELVELPAKEEKkttvtsqqrraaakssrsk 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 1087 -YIIINKL--GYHT---------GNLVASYLDRPKFGLLMVVLSLIFMKGNCVREDLIFNFLFKLGLD---VRETNGLFG 1151
Cdd:pfam01454 81 sYILVSTLppEYRVpaiiwpskaPSFVLDQDEATYTGILTVILSLILLSGGSISEQELLRYLRRLGIDtdgTKEIPPLNG 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 257900508 1152 NTKKLITEvFVRQKYLEYRRIPYTEPAE--YEFLWGPRAFLETSKM 1195
Cdd:pfam01454 161 NTDDLLKR-LVKQGYLVRTKEGASDDGEeiIEYRVGPRAKVEFGPE 205
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
9-576 |
1.51e-21 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 102.32 E-value: 1.51e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 9 GDSSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPpalgGP 88
Cdd:PHA03247 2500 GGGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRMLTWIRGLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRP----AP 2575
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 89 IVPAPPLGGPMGKPPTPGVlMVHPPPPGAPMAQPPTPGvlmvhPSAPGAPMAHPPPPgtpmshPPPPGTPMAHPPPPGTP 168
Cdd:PHA03247 2576 RPSEPAVTSRARRPDAPPQ-SARPRAPVDDRGDPRGPA-----PPSPLPPDTHAPDP------PPPSPSPAANEPDPHPP 2643
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 169 MAHPPP------PGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPmaHPPPPGTPMAHPPPPGTPMAQPPAPGVlMAQP 242
Cdd:PHA03247 2644 PTVPPPerprddPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAAR--PTVGSLTSLADPPPPPPTPEPAPHALV-SATP 2720
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 243 LTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSG-APMAKPPGPGVlmihPPGARAPmtQPPASGAPMAQPAAPPAQPMAP 321
Cdd:PHA03247 2721 LPPGPAAARQASPALPAAPAPPAVPAGPATPGGpARPARPPTTAG----PPAPAPP--AAPAAGPPRRLTRPAVASLSES 2794
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 322 PAQPMASWAPQAQPLilqiqsqVIRAPPQVPQGPQAPPAQLATPPGWQATSPgwqATQQGWQATPLTWQTtqvtWQAPAV 401
Cdd:PHA03247 2795 RESLPSPWDPADPPA-------AVLAPAAALPPAASPAGPLPPPTSAQPTAP---PPPPGPPPPSLPLGG----SVAPGG 2860
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 402 TWQvpppmrqgpppirpgpppirpgpppvRQAPPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQ 481
Cdd:PHA03247 2861 DVR--------------------------RRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAP 2914
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 482 APPVIRQAPPLIRQAPPPIRPAPqvlatQPPLWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPqV 561
Cdd:PHA03247 2915 PPPQPQPQPPPPPQPQPPPPPPP-----RPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSRE-A 2988
|
570
....*....|....*
gi 257900508 562 PQPVLPAPLSAPLSA 576
Cdd:PHA03247 2989 PASSTPPLTGHSLSR 3003
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
108-748 |
3.12e-20 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 98.09 E-value: 3.12e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 108 LMVHPPPPGAPMAQPPTpgvlmvHPSAPGAPMAHPPPPGTPMSHPPPPGTPmAHPPPPGTPMAhppPPGTPmVHP----- 182
Cdd:PHA03247 2468 LLLGELFPGAPVYRRPA------EARFPFAAGAAPDPGGGGPPDPDAPPAP-SRLAPAILPDE---PVGEP-VHPrmltw 2536
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 183 -----PPPGTPMAHPPPPGTPMahPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGvLMAQPLTPGVLMVQPAAPGA 257
Cdd:PHA03247 2537 irgleELASDDAGDPPPPLPPA--APPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPP-QSARPRAPVDDRGDPRGPAP 2613
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 258 PMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARApmTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLI 337
Cdd:PHA03247 2614 PSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERP--RDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPT 2691
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 338 LQIQSQVIRAPPQVPQGPQAPPAQLATPPgwqaTSPGWQATQQGWQATPLTwqttqvtwqapavtwqvpppmrqgpppir 417
Cdd:PHA03247 2692 VGSLTSLADPPPPPPTPEPAPHALVSATP----LPPGPAAARQASPALPAA----------------------------- 2738
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 418 pgpppirpgpppvrQAPPLIRQAPPVirQAPPVIRQAPPVIRQAPAvirQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAP 497
Cdd:PHA03247 2739 --------------PAPPAVPAGPAT--PGGPARPARPPTTAGPPA---PAPPAAPAAGPPRRLTRPAVASLSESRESLP 2799
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 498 PPIRPAPQVLATqpplwqalppppplrqapQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAP 577
Cdd:PHA03247 2800 SPWDPADPPAAV------------------LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGD 2861
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 578 QAVHCPSiiwQAPKGQPPVPHEIPTS-MEFQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQ 656
Cdd:PHA03247 2862 VRRRPPS---RSPAAKPAAPARPPVRrLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR 2938
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 657 KAVQIQLPPQQAQASGPQAEVPTL---PLQPSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRASSIDRRGSSK 733
Cdd:PHA03247 2939 PQPPLAPTTDPAGAGEPSGAVPQPwlgALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSLALHEETD 3018
|
650
....*....|....*
gi 257900508 734 ERRTSSKERRAPSKD 748
Cdd:PHA03247 3019 PPPVSLKQTLWPPDD 3033
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
7-330 |
6.45e-17 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 87.30 E-value: 6.45e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 7 NLGDSSPPAEAPKPPvySRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALG 86
Cdd:PHA03247 2697 SLADPPPPPPTPEPA--PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAA 2774
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 87 GPIVPAPPLGGPMGKP-------------PTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPgtpmshpp 153
Cdd:PHA03247 2775 PAAGPPRRLTRPAVASlsesreslpspwdPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPP-------- 2846
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 154 PPGTPMAHPPPPGTPMAHPPPPGTPmvhPPPPGTPmAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPP 233
Cdd:PHA03247 2847 PPSLPLGGSVAPGGDVRRRPPSRSP---AAKPAAP-ARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQ 2922
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 234 APGVLMAQPltpgvlmvQPAAPGAPmvqPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAA 313
Cdd:PHA03247 2923 PPPPPQPQP--------PPPPPPRP---QPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPAS 2991
|
330
....*....|....*..
gi 257900508 314 PPAQPMAPPAQPMASWA 330
Cdd:PHA03247 2992 STPPLTGHSLSRVSSWA 3008
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
59-287 |
1.98e-15 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 81.65 E-value: 1.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 59 QAPQPAWEAPQgQLPAPVVPMTQPPALGGPIVPAPPLGgpmgkpPTPgvlmvHPPPPGAPMAQPPT---PGVLMVHPSaP 135
Cdd:PHA03378 612 QSHIPETSAPR-QWPMPLRPIPMRPLRMQPITFNVLVF------PTP-----HQPPQVEITPYKPTwtqIGHIPYQPS-P 678
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 136 GAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPP 215
Cdd:PHA03378 679 TGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPA 758
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 216 GTPMAHPPPPGTPMAQPPAPgvlmaQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVL 287
Cdd:PHA03378 759 AAPGRARPPAAAPGAPTPQP-----PPQAPPAPQQRPRGAPTPQPPPQAGPTSMQLMPRAAPGQQGPTKQIL 825
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
53-267 |
6.71e-13 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 73.48 E-value: 6.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 53 ASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVlmvHPPPPGAPMAQPPTPGVLMVHP 132
Cdd:PRK07764 595 AGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAA---PEHHPKHVAVPDASDGGDGWPA 671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 133 SAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAhpPPPGTPMAHPPPPGTPMAHP 212
Cdd:PRK07764 672 KAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGAS--APSPAADDPVPLPPEPDDPP 749
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 257900508 213 PPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAM 267
Cdd:PRK07764 750 DPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEV 804
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
113-303 |
1.30e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 69.24 E-value: 1.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 113 PPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHP 192
Cdd:PRK07764 596 GGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 193 PPPGTPMAHPPPPGTPMAHPPPPGTPmAHPPPPGTPMAQPPAPGVLMAQPLTPGVlmvqPAAPGAPMVQPPPAAMMTQPQ 272
Cdd:PRK07764 676 AAPAAPPPAPAPAAPAAPAGAAPAQP-APAPAATPPAGQADDPAAQPPQAAQGAS----APSPAADDPVPLPPEPDDPPD 750
|
170 180 190
....*....|....*....|....*....|.
gi 257900508 273 PSGAPMAKPPGPGVLMIHPPGARAPMTQPPA 303
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE 781
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
81-305 |
2.17e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 68.36 E-value: 2.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 81 QPPALGGPIVPAPPLGGPMGKPPTPGVlmvhPPPPGAPmaqPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMA 160
Cdd:PRK12323 364 RPGQSGGGAGPATAAAAPVAQPAPAAA----APAAAAP---APAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAA 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 161 HPPPPGTPMAHPPPPGTPMVHP-PPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPmahPPPPGTPMAQPPAPGVLM 239
Cdd:PRK12323 437 RQASARGPGGAPAPAPAPAAAPaAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDD---PPPWEELPPEFASPAPAQ 513
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 257900508 240 AQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASG 305
Cdd:PRK12323 514 PDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDG 579
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
115-572 |
1.29e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 65.78 E-value: 1.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 115 PGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPmAHPPPPGTPMVHPPPPGTPMAHPPP 194
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAP-APPSPAGNAPAGGAPSPPPAAAPSA 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 195 PGTPMAHPPPPGTPMAHPPPP--GTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMvqpppAAMMTQPQ 272
Cdd:PRK07764 465 QPAPAPAAAPEPTAAPAPAPPaaPAPAAAPAAPAAPAAPAGADDAATLRERWPEILAAVPKRSRKTW-----AILLPEAT 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 273 PSGapmakPPGPGVLMIHP-PGARAPMTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQV 351
Cdd:PRK07764 540 VLG-----VRGDTLVLGFStGGLARRFASPGNAEVLVTALAEELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAAR 614
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 352 PQGPQAPPAQLATPPGWQATSPGWQATQQGWQATPltwqttqvtwqapavtwqvpppmrqgpPPIRPGPPPIRPGPPPVR 431
Cdd:PRK07764 615 PAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAA---------------------------PEHHPKHVAVPDASDGGD 667
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 432 QAPPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPvirQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQP 511
Cdd:PRK07764 668 GWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPA---ATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPE 744
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 257900508 512 PLWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSA 572
Cdd:PRK07764 745 PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEEVA 805
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
57-266 |
1.32e-10 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 65.67 E-value: 1.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 57 AWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPG 136
Cdd:PRK12323 362 AFRPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASA 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 137 APMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAhPPPPG 216
Cdd:PRK12323 442 RGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPD-AAPAG 520
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 257900508 217 TPMAHPPPPGTPMAQPPAPGvlmAQPLTPGVLMVQPAAPGAPMVQPPPAA 266
Cdd:PRK12323 521 WVAESIPDPATADPDDAFET---LAPAPAAAPAPRAAAATEPVVAPRPPR 567
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
34-235 |
2.07e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 65.39 E-value: 2.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 34 PASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVP---MTQPPALGGPIVPAPPLGGPMGKPPTPGVLMV 110
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAapaEASAAPAPGVAAPEHHPKHVAVPDASDGGDGW 669
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 111 HPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVhpPPPGTPMA 190
Cdd:PRK07764 670 PAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPV--PLPPEPDD 747
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 257900508 191 HPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAP 235
Cdd:PRK07764 748 PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPS 792
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
112-477 |
2.74e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 65.01 E-value: 2.74e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 112 PPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPmAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAH 191
Cdd:PRK07764 393 APAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAP-APPSPAGNAPAGGAPSPPPAAAPSAQPAPAPA 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 192 PPPPGTpmahPPPPGTPMAHPPPPGTPmAHPPPPGTPMAQPPAPGVLMAQP----------LTPGVLMVQPAAPGAP--- 258
Cdd:PRK07764 472 AAPEPT----AAPAPAPPAAPAPAAAP-AAPAAPAAPAGADDAATLRERWPeilaavpkrsRKTWAILLPEATVLGVrgd 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 259 -----MVQPPPAAMMTQPQ--------------------------PSGAPMAKPPGPGVLMIHPPGARAPMTQPPASGAP 307
Cdd:PRK07764 547 tlvlgFSTGGLARRFASPGnaevlvtalaeelggdwqveavvgpaPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAA 626
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 308 MAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPGWQAtSPGWQATQQGWQATPL 387
Cdd:PRK07764 627 PAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAA-PAAPAGAAPAQPAPAP 705
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 388 TWQTTQVTWQAPAVTWQVPPPMRQGPPPIRPGPPPIRPGPPpvrqAPPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQ 467
Cdd:PRK07764 706 AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPD----DPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSE 781
|
410
....*....|
gi 257900508 468 APPVIRQAPP 477
Cdd:PRK07764 782 EEEMAEDDAP 791
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
9-224 |
4.94e-10 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 63.74 E-value: 4.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 9 GDSSPPAEAPKPPVYSRPTVlmRAPPASSRAPPVPWDPPPidLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGP 88
Cdd:PRK12323 370 GGAGPATAAAAPVAQPAPAA--AAPAAAAPAPAAPPAAPA--AAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPG 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 89 IVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGvlmvHPSAPGAPMAHPPPPGTPMshPPPPGTPMAHPPPPGTP 168
Cdd:PRK12323 446 GAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARA----APAAAPAPADDDPPPWEEL--PPEFASPAPAQPDAAPA 519
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 257900508 169 MAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPP 224
Cdd:PRK12323 520 GWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
76-279 |
5.22e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 63.85 E-value: 5.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 76 VVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPP 155
Cdd:PRK07764 586 AVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDG 665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 156 GTPMAHPPPPGTPMAhPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHP--------PPPGT 227
Cdd:PRK07764 666 GDGWPAKAGGAAPAA-PPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPspaaddpvPLPPE 744
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 257900508 228 PMAQP-PAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMA 279
Cdd:PRK07764 745 PDDPPdPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDED 797
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
9-361 |
5.94e-10 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 63.92 E-value: 5.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 9 GDSSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAawQAPQPAWEAPQGQLPaPVVPMTQPPAL--- 85
Cdd:PHA03379 414 GTPRPPVEKPRPEVPQSLETATSHGSAQVPEPPPVHDLEPGPLHDQHS--MAPCPVAQLPPGPLQ-DLEPGDQLPGVvqd 490
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 86 -GGPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQP------PTPGVLMVHPSAPGAPMAHPPPPGTP-------MSH 151
Cdd:PHA03379 491 gRPACAPVPAPAGPIVRPWEASLSQVPGVAFAPVMPQPmpvepvPVPTVALERPVCPAPPLIAMQGPGETsgivrvrERW 570
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 152 PPPPGTPMAHPPPPGTPMAHPPPPGTPMVHP-------PPPGTPMAhppPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPP 224
Cdd:PHA03379 571 RPAPWTPNPPRSPSQMSVRDRLARLRAEAQPyqasvevQPPQLTQV---SPQQPMEYPLEPEQQMFPGSPFSQVADVMRA 647
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 225 PGTPMAQPPAPGVLMAQPLTPGVlmvqPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPgARAPMTQPPAS 304
Cdd:PHA03379 648 GGVPAMQPQYFDLPLQQPISQGA----PLAPLRASMGPVPPVPATQPQYFDIPLTEPINQGASAAHFL-PQQPMEGPLVP 722
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 257900508 305 GAPMAQPAAPPAQPMAPPAQPMASWAPQAQPliLQIQSQVIRAPPQVPQGPQAPPAQ 361
Cdd:PHA03379 723 ERWMFQGATLSQSVRPGVAQSQYFDLPLTQP--INHGAPAAHFLHQPPMEGPWVPEQ 777
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
112-273 |
1.04e-09 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 63.13 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 112 PPPPGAPMAQPPTPGVLMVHPSAPGAPM-------------AHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTP 178
Cdd:pfam09770 166 APKKAAAPAPAPQPAAQPASLPAPSRKMmsleeveaamraqAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 179 ---MVHPPPPGTPMAHPPPPGT-PMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAA 254
Cdd:pfam09770 246 pqqQPQQPQQHPGQGHPVTILQrPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQ 325
|
170 180
....*....|....*....|....*.
gi 257900508 255 PGAPM-------VQPPPAAMMTQPQP 273
Cdd:pfam09770 326 PAPAHqahrqqgSFGRQAPIITHPQQ 351
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
11-201 |
1.92e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 62.31 E-value: 1.92e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 11 SSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPIV 90
Cdd:PRK07764 606 SGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAP 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 91 PAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHP--PPPGTPMSHPPPPGTPMAHPPPPGTP 168
Cdd:PRK07764 686 APAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDpvPLPPEPDDPPDPAGAPAQPPPPPAPA 765
|
170 180 190
....*....|....*....|....*....|...
gi 257900508 169 MAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAH 201
Cdd:PRK07764 766 PAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDR 798
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
9-221 |
4.53e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 60.77 E-value: 4.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 9 GDSSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPpiDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGP 88
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAP--AGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDG 668
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 89 IVPAPPLGGPMGKPPTPGVlMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMShpPPPGTPMAHPPPPGTP 168
Cdd:PRK07764 669 WPAKAGGAAPAAPPPAPAP-AAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGAS--APSPAADDPVPLPPEP 745
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 257900508 169 MAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAH 221
Cdd:PRK07764 746 DDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDR 798
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
50-300 |
8.16e-09 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 60.17 E-value: 8.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 50 DLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPI-VPAPPLGGPMGKPPTPgvlmvHPPPPGAPMAQPPTPGVL 128
Cdd:pfam03154 159 DSSAQQQILQTQPPVLQAQSGAASPPSPPPPGTTQAATAGpTPSAPSVPPQGSPATS-----QPPNQTQSTAAPHTLIQQ 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 129 MVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPP----PGTPMAHPPPPGTPmvHPPPPGTPMAHPPPPGTPMAHPPP 204
Cdd:pfam03154 234 TPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPslhgQMPPMPHSLQTGPS--HMQHPVPPQPFPLTPQSSQSQVPP 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 205 PGTPMAHPPPPGTPMAHPPPPGTPMAQPPapgvlMAQPLTPGVLMV-----QPAAPGAPMVQPPP---AAMMTQPQPSGA 276
Cdd:pfam03154 312 GPSPAAPGQSQQRIHTPPSQSQLQSQQPP-----REQPLPPAPLSMphikpPPTTPIPQLPNPQShkhPPHLSGPSPFQM 386
|
250 260 270
....*....|....*....|....*....|
gi 257900508 277 PMAKPPGPGVLMI------HPPGARAPMTQ 300
Cdd:pfam03154 387 NSNLPPPPALKPLsslsthHPPSAHPPPLQ 416
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
56-366 |
1.04e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 59.61 E-value: 1.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 56 AAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAP 135
Cdd:PRK07764 403 AAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAP 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 136 GAPMAHPPP--PGTPMSHPPPPGTP------------------------------------------MAHPPPP------ 165
Cdd:PRK07764 483 APPAAPAPAaaPAAPAAPAAPAGADdaatlrerwpeilaavpkrsrktwaillpeatvlgvrgdtlvLGFSTGGlarrfa 562
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 166 --------------------------GTPMAHPPPPGTPMVHPPPPGTPMAHP---PPPGTPMAHPPPPGTPMAHPPPPG 216
Cdd:PRK07764 563 spgnaevlvtalaeelggdwqveavvGPAPGAAGGEGPPAPASSGPPEEAARPaapAAPAAPAAPAPAGAAAAPAEASAA 642
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 217 TPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARA 296
Cdd:PRK07764 643 PAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPP 722
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 297 PMTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPP 366
Cdd:PRK07764 723 QAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPS 792
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
135-271 |
1.05e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 59.34 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 135 PGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGtpmahPPPPGTPMAHPPP 214
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVA-----APAAAAPAAAPAA 440
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 257900508 215 PGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPgvlmvQPAAPGAPMVQPPPAAMMTQP 271
Cdd:PRK14951 441 APAAVALAPAPPAQAAPETVAIPVRVAPEPA-----VASAAPAPAAAPAAARLTPTE 492
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
50-243 |
1.12e-08 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 59.66 E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 50 DLQASLAAWQAPqpawEAPQGQLPAPVVPMTQPPALGGPI--------VPAPPLGGPMGKPPTPGVLMVHPP-PPGAPMA 120
Cdd:pfam09770 155 DLQVDASLWGVA----PKKAAAPAPAPQPAAQPASLPAPSrkmmsleeVEAAMRAQAKKPAQQPAPAPAQPPaAPPAQQA 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 121 QPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGT-PMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPM---AHPPPPG 196
Cdd:pfam09770 231 QQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQrPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTqilQNPNRLS 310
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 257900508 197 TPMAHPPPPGTPMAHPPPPgtpmaHPPPPGTPMAQPPAPGVLMAQPL 243
Cdd:pfam09770 311 AARVGYPQNPQPGVQPAPA-----HQAHRQQGSFGRQAPIITHPQQL 352
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
439-701 |
1.16e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 59.50 E-value: 1.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 439 QAPPVIRQAPPVIRQAPPVIRQAPAVIRQA-PPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPPLWQAL 517
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAaPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAP 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 518 PPPPPLRQAPQARLPAPQVQAAPQVPTAPPATQVPAAPPA-GPQVPQPVLPAPLSAPLSAPQAVHCPSIIWQAPKGQPPV 596
Cdd:PRK12323 451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPApADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPA 530
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 597 PHEIPTSMEFQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAP------PSQKAVQIQLPPQQAQA 670
Cdd:PRK12323 531 TADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAARlpvrglAQQLARQSELAGVEGDT 610
|
250 260 270
....*....|....*....|....*....|.
gi 257900508 671 SGPQAEVPTLPLQPSWQAPPAVLQAQPGPPV 701
Cdd:PRK12323 611 VRLRVPVPALAEAEVVERLQAALTEHFGQPV 641
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
110-226 |
1.23e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 59.34 E-value: 1.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 110 VHPPPPGAPMAQPPTPgvlmvhPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPM 189
Cdd:PRK14951 381 PARPEAAAPAAAPVAQ------AAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQ 454
|
90 100 110
....*....|....*....|....*....|....*..
gi 257900508 190 AHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPG 226
Cdd:PRK14951 455 AAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPT 491
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
13-335 |
1.31e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 59.23 E-value: 1.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 13 PPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPIVPA 92
Cdd:PRK07764 422 APAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPA 501
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 93 PPLGGP------------------------MGKPPTPGVLMVHP---------PPPGAPMAQPPTPGVLM---------- 129
Cdd:PRK07764 502 APAGADdaatlrerwpeilaavpkrsrktwAILLPEATVLGVRGdtlvlgfstGGLARRFASPGNAEVLVtalaeelggd 581
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 130 -----VHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPP-PPGTPMVHPPPPGTPMAHPPPPGTPMAHPP 203
Cdd:PRK07764 582 wqveaVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAgAAAAPAEASAAPAPGVAAPEHHPKHVAVPD 661
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 204 PPGTPMAHPPPPGTPM-AHPPPPGTPMAQPPAPGVLMAQPltpgvlmvQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPP 282
Cdd:PRK07764 662 ASDGGDGWPAKAGGAApAAPPPAPAPAAPAAPAGAAPAQP--------APAPAATPPAGQADDPAAQPPQAAQGASAPSP 733
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 257900508 283 GPGVLMIHPPGARApmtqPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQP 335
Cdd:PRK07764 734 AADDPVPLPPEPDD----PPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEE 782
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
89-390 |
1.76e-08 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 58.93 E-value: 1.76e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 89 IVPAPPLGgPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPP----PPGTPMSHPPPPGTPMAHPPP 164
Cdd:PHA03378 563 LLPAPGLG-PLQIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEPPTTQSHIPetsaPRQWPMPLRPIPMRPLRMQPI 641
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 165 PGTPMAHPPPPGTPMVHPPPPGTPMAHP------PPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPM-AQPPAPGV 237
Cdd:PHA03378 642 TFNVLVFPTPHQPPQVEITPYKPTWTQIghipyqPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGrAQRPAAAT 721
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 238 LMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVlmihpPGARAPMTQPPAsgapmaqpaappaq 317
Cdd:PHA03378 722 GRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAA-----PGAPTPQPPPQA-------------- 782
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 257900508 318 PMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPGWQATSPGWQATQQGWQATPLTWQ 390
Cdd:PHA03378 783 PPAPQQRPRGAPTPQPPPQAGPTSMQLMPRAAPGQQGPTKQILRQLLTGGVKRGRPSLKKPAALERQAAAGPT 855
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
137-232 |
1.83e-08 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 59.32 E-value: 1.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 137 APMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPP----PPGTPMAHPPPPGTPMAHp 212
Cdd:PTZ00395 412 AGYSNPGNSNPGYNNAPNSNTPYNNPPNSNTPYSNPPNSNPPYSNLPYSNTPYSNAPlsnaPPSSAKDHHSAYHAAYQH- 490
|
90 100
....*....|....*....|
gi 257900508 213 PPPGTPMAHPPPPGTPMAQP 232
Cdd:PTZ00395 491 RAANQPAANLPTANQPAANN 510
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
83-449 |
1.97e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 58.84 E-value: 1.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 83 PALGGPIVPAPPLGGPMGKPPTPGvlMVHPPPPGAPMAQPPTPGVLMVHPsAPGAPMAHPPPPGTPMSHPPPPGTPMAHP 162
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAA--PAPAAAAPAAAAAPAPAAAPQPAP-APAPAPAPPSPAGNAPAGGAPSPPPAAAP 462
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 163 PPPGTPMAHPPPPGTPMVHPPPPGTPmAHPPPPGTPMAHPPPPG-------------------------------TPMAH 211
Cdd:PRK07764 463 SAQPAPAPAAAPEPTAAPAPAPPAAP-APAAAPAAPAAPAAPAGaddaatlrerwpeilaavpkrsrktwaillpEATVL 541
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 212 PPPPGT-PMAHPPPP-GTPMAQPPAPGVLM--------------AQPLTPGVlMVQPAAPGAPmVQPPPAAMMTQPQPSG 275
Cdd:PRK07764 542 GVRGDTlVLGFSTGGlARRFASPGNAEVLVtalaeelggdwqveAVVGPAPG-AAGGEGPPAP-ASSGPPEEAARPAAPA 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 276 APMAKPPGPGvlmihPPGARAPMTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGP 355
Cdd:PRK07764 620 APAAPAAPAP-----AGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPA 694
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 356 QAPPAQLATPPGWQATSPGWQATQQGWQatpltwQTTQVTWQAPAVTWQVPPPMRQGPPPIRPGPPPIRPGPPPVRQAPP 435
Cdd:PRK07764 695 GAAPAQPAPAPAATPPAGQADDPAAQPP------QAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAA 768
|
410
....*....|....
gi 257900508 436 LIRQAPPVIRQAPP 449
Cdd:PRK07764 769 APAAAPPPSPPSEE 782
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
73-393 |
3.73e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 58.07 E-value: 3.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 73 PAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLmVHPSAPGAPMAHPPPPGTPMSHP 152
Cdd:PRK07764 390 GAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPA-GNAPAGGAPSPPPAAAPSAQPAP 468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 153 PPPGTPMAHPPPPGTPMAHPPPPGTPmvHPPPPGTPMAHPPPPGTP---------------------------------- 198
Cdd:PRK07764 469 APAAAPEPTAAPAPAPPAAPAPAAAP--AAPAAPAAPAGADDAATLrerwpeilaavpkrsrktwaillpeatvlgvrgd 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 199 ---MAHPPPP--------------------------------GTPMAHPPPPGTPMAHPPPPGTPMAQPPAPG--VLMAQ 241
Cdd:PRK07764 547 tlvLGFSTGGlarrfaspgnaevlvtalaeelggdwqveavvGPAPGAAGGEGPPAPASSGPPEEAARPAAPAapAAPAA 626
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 242 PLTPGvlmvQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAAPPAQPMAP 321
Cdd:PRK07764 627 PAPAG----AAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA 702
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 322 PAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPGWQATSPGWQATQQGWQATPLTWQTTQ 393
Cdd:PRK07764 703 PAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAP 774
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
532-683 |
5.86e-08 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 57.35 E-value: 5.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 532 PAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPSIIWQAPKGQPPVPHEIPTSMEFQEVQQ 611
Cdd:pfam09770 211 AQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTILQRPQSPQPDPAQPSIQPQAQQFHQ 290
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 612 TQAlawQAQKAPTHIWQplpaqEAQRQAPPLVQLEQPFQGAPPSQKAVQIQlppQQAQASGPQAEVPTLPLQ 683
Cdd:pfam09770 291 QPP---PVPVQPTQILQ-----NPNRLSAARVGYPQNPQPGVQPAPAHQAH---RQQGSFGRQAPIITHPQQ 351
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
114-246 |
6.08e-08 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 57.03 E-value: 6.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 114 PPGAPMAQPPTPGVLMVHPSAPgAPMAHPPPPGT--PMSHPPPPGtpmAHPPPPGTPMAHPPPPgtpmVHPPPPGTPMAH 191
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAA-APAAAPVAQAAaaPAPAAAPAA---AASAPAAPPAAAPPAP----VAAPAAAAPAAA 437
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 257900508 192 PPPPGTPmAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPG 246
Cdd:PRK14951 438 PAAAPAA-VALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPT 491
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
12-365 |
7.39e-08 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 57.08 E-value: 7.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 12 SPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAP----QPAWEAPQGQLPAPVVPMTQ------ 81
Cdd:pfam03154 178 SGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPhtliQQTPTLHPQRLPSPHPPLQPmtqppp 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 82 PPALGGPIVPAPPLGGPMgkPPTPGVLMVHPPPPGAPMAQPPTP-GVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMA 160
Cdd:pfam03154 258 PSQVSPQPLPQPSLHGQM--PPMPHSLQTGPSHMQHPVPPQPFPlTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQ 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 161 HPPPPGTPMAHPPPPGTPMVHPPPP------GTPMAH--------PPPPGTPMAHPPPPG-TPMAHPPPPGTPMAHPPpp 225
Cdd:pfam03154 336 SQQPPREQPLPPAPLSMPHIKPPPTtpipqlPNPQSHkhpphlsgPSPFQMNSNLPPPPAlKPLSSLSTHHPPSAHPP-- 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 226 gtPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASG 305
Cdd:pfam03154 414 --PLQLMPQSQQLPPPPAQPPVLTQSQSLPPPAASHPPTSGLHQVPSQSPFPQHPFVPGGPPPITPPSGPPTSTSSAMPG 491
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 306 APMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQiQSQVIRAPPQVPQGPQAPPAQLATP 365
Cdd:pfam03154 492 IQPPSSASVSSSGPVPAAVSCPLPPVQIKEEALD-EAEEPESPPPPPRSPSPEPTVVNTP 550
|
|
| BimA_second |
NF040983 |
trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia ... |
148-235 |
9.65e-08 |
|
trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia intracellular motility A), WP_004266405.1-like proteins in Burkholderia mallei or B. pseudomallei. The term BimA has also been used for WP_011205626.1-like homologs that have a very different N-terminal half.
Pssm-ID: 468913 [Multi-domain] Cd Length: 382 Bit Score: 55.68 E-value: 9.65e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 148 PMSHPPPPGTPMAHPPPPGTPMAHPPPPgtpmvhPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGT 227
Cdd:NF040983 86 PNKVPPPPPPPPPPPPPPPTPPPPPPPP------PPPPPPSPPPPPPPSPPPSPPPPTTTPPTRTTPSTTTPTPSMHPIQ 159
|
....*...
gi 257900508 228 PMAQPPAP 235
Cdd:NF040983 160 PTQLPSIP 167
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
68-206 |
1.30e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 55.88 E-value: 1.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 68 PQGQLPAPVVPMTQPPAlggPIVPAPPLGGPMGKPPTPGVlmVHPPPPGAPMAQPPTPgvlmvhPSAPGAPMAhPPPPGT 147
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPA---RPEAAAPAAAPVAQAAAAPA--PAAAPAAAASAPAAPP------AAAPPAPVA-APAAAA 433
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 257900508 148 PMSHPPPPGTPmAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPG 206
Cdd:PRK14951 434 PAAAPAAAPAA-VALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPT 491
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
434-913 |
1.35e-07 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 56.49 E-value: 1.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 434 PPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPPL 513
Cdd:PHA03247 2593 PQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGR 2672
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 514 WQALPPPPPLRQAPQARLPAPQVQAAPQvPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPsiiwqapkgq 593
Cdd:PHA03247 2673 AAQASSPPQRPRRRAARPTVGSLTSLAD-PPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAP---------- 2741
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 594 PPVPHEIPTSMEFQEVQQTQALAwqAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQLPPQQAQASGP 673
Cdd:PHA03247 2742 PAVPAGPATPGGPARPARPPTTA--GPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALP 2819
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 674 QAEVPTLPLQPswqaPPAVLQAQPGPPVAAANFPLGSAKSLmTPSGECRassidrrgsskerrtsskeRRAPSKDRMIFA 753
Cdd:PHA03247 2820 PAASPAGPLPP----PTSAQPTAPPPPPGPPPPSLPLGGSV-APGGDVR-------------------RRPPSRSPAAKP 2875
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 754 ATFCAPKAVSAARAHLPAAWKNLPATPETFAPsssvfPATSQFQPASLNAFKGPSAASETPKSLPYALQDPFACVEALPA 833
Cdd:PHA03247 2876 AAPARPPVRRLARPAVSRSTESFALPPDQPER-----PPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPA 2950
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 834 VPWVPQPNMNASKASQAVPTFLMATAAAPQATATTQEASKTSVEPPRRsgkatrkkkHLEAQEDSRGHTLAFHDWQGPRP 913
Cdd:PHA03247 2951 GAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTG---------HSLSRVSSWASSLALHEETDPPP 3021
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
123-215 |
2.92e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 54.82 E-value: 2.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 123 PTPGVLMVHPSAPGAPMAHPPPpgTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPmahPPPPGTPMAHP 202
Cdd:PRK14950 362 PVPAPQPAKPTAAAPSPVRPTP--APSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTP---ESAPKLTRAAI 436
|
90
....*....|...
gi 257900508 203 PPPGTPMAHPPPP 215
Cdd:PRK14950 437 PVDEKPKYTPPAP 449
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
132-241 |
4.22e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 54.43 E-value: 4.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 132 PSAPGAPMAHPPPPGTPMSHPP-PPGTPMAHPPPPGTPMAHPPPPgtPMVHPPPPGTPMAHPPPpgtpmahPPPPGTPMA 210
Cdd:PRK14950 365 APQPAKPTAAAPSPVRPTPAPStRPKAAAAANIPPKEPVRETATP--PPVPPRPVAPPVPHTPE-------SAPKLTRAA 435
|
90 100 110
....*....|....*....|....*....|.
gi 257900508 211 HPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQ 241
Cdd:PRK14950 436 IPVDEKPKYTPPAPPKEEEKALIADGDVLEQ 466
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
52-280 |
5.13e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 54.41 E-value: 5.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 52 QASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPiVPAPPLGGPMGKPPTPGvlmvHPPPPGAPMAQPPTPGVlmVH 131
Cdd:PHA03307 23 RPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGA-AACDRFEPPTGPPPGPG----TEAPANESRSTPTWSLS--TL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 132 PSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPgtpmahPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPmAH 211
Cdd:PHA03307 96 APASPAREGSPTPPGPSSPDPPPPTPPPASPPPS------PAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDA-AS 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 257900508 212 PPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLtpgvlmvqPAAPGAPMVQPPPAAMMTQPQPSGAPMAK 280
Cdd:PHA03307 169 SRQAALPLSSPEETARAPSSPPAEPPPSTPPA--------AASPRPPRRSSPISASASSPAPAPGRSAA 229
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
74-305 |
5.24e-07 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 54.32 E-value: 5.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 74 APVVPMTQ-PPALGGPIVPAPPLggpMGKPPTPGVLMVHPPPPGAPMAQPPTPGvlMVHPSAP-GAPMAHPPPPGTPMSH 151
Cdd:PRK10263 335 APVEPVTQtPPVASVDVPPAQPT---VAWQPVPGPQTGEPVIAPAPEGYPQQSQ--YAQPAVQyNEPLQQPVQPQQPYYA 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 152 PPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMaHPPPPGTPMAHPP--PPGTPMAHPPPPGTPMAHPPPPGTPM 229
Cdd:PRK10263 410 PAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAW-QAEEQQSTFAPQStyQTEQTYQQPAAQEPLYQQPQPVEQQP 488
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 257900508 230 AQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQ-PQPSGAPMAKPPG--PGVLMIHPPGARAPMTQPPASG 305
Cdd:PRK10263 489 VVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPiPEPVKEPEPIKSSlkAPSVAAVPPVEAAAAVSPLASG 567
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
129-237 |
5.62e-07 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 53.82 E-value: 5.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 129 MVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPgtPMAHPPPPGTPmvHPPPPGTPMAhpPPPGTPMAHPPPPGTP 208
Cdd:PRK06995 50 ALAPPAAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPW--LVEHAKRLTAQ--REQLVARAAA--PAAPEAQAPAAPAERA 123
|
90 100
....*....|....*....|....*....
gi 257900508 209 MAHPPPPGTPMAHPPPPGTPMAQPPAPGV 237
Cdd:PRK06995 124 AAENAARRLARAAAAAPRPRVPADAAAAV 152
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
108-205 |
8.09e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 53.27 E-value: 8.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 108 LMVHPPPPGAPMAQPPTPGvlmvhPSAPGAPMAHPPPPGTPMSHPP-PPGTPMAHPPPPGTPMAHPPPPGTPmvhPPPPG 186
Cdd:PRK14950 359 LLVPVPAPQPAKPTAAAPS-----PVRPTPAPSTRPKAAAAANIPPkEPVRETATPPPVPPRPVAPPVPHTP---ESAPK 430
|
90
....*....|....*....
gi 257900508 187 TPMAHPPPPGTPMAHPPPP 205
Cdd:PRK14950 431 LTRAAIPVDEKPKYTPPAP 449
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
532-683 |
1.03e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 53.18 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 532 PAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPSIIWQAPKGQPPVPHEIPTSMEFQEVQQ 611
Cdd:PRK14951 373 AAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPP 452
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 612 TQALAWQAQKAPTHiwQPLPAQEAQRQAPPLVQLEQPFQGAPPSQkaVQIQLPPQQAQASGPQAEVPTLPLQ 683
Cdd:PRK14951 453 AQAAPETVAIPVRV--APEPAVASAAPAPAAAPAAARLTPTEEGD--VWHATVQQLAAAEAITALARELALQ 520
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
67-185 |
1.07e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 52.89 E-value: 1.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 67 APQGQLP-------APVVPMTqPPALGGPIVPAPPlggpmGKPPTPGVLMvhPPPPGAPMAQPPTPgvlmvhpsaPGAPM 139
Cdd:PRK14950 344 TSYGQLPlelavieALLVPVP-APQPAKPTAAAPS-----PVRPTPAPST--RPKAAAAANIPPKE---------PVRET 406
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 257900508 140 AHPPPPGTPMSHPPPPGTPmahPPPPGTPMAHPPPPGTPMVHPPPP 185
Cdd:PRK14950 407 ATPPPVPPRPVAPPVPHTP---ESAPKLTRAAIPVDEKPKYTPPAP 449
|
|
| Drf_FH1 |
pfam06346 |
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs) ... |
91-236 |
1.20e-06 |
|
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues.
Pssm-ID: 461881 [Multi-domain] Cd Length: 157 Bit Score: 49.48 E-value: 1.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 91 PAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPmahpPPPGTPMSHPPPP---GTPMAHPPP-PG 166
Cdd:pfam06346 2 PPPPLPGDSSTIPLPPGACIPTPPPLPGGGGPPPPPPLPGSAAIPPPP----PLPGGTSIPPPPPlpgAASIPPPPPlPG 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 167 TPMAHPPPPGTPMVHPPPPGTPMahPPPPGTPMAHPPPPGTPMAHPPP--PGTPMAHPPPPGTPMAQPPAPG 236
Cdd:pfam06346 78 STGIPPPPPLPGGAGIPPPPPPL--PGGAGVPPPPPPLPGGPGIPPPPpfPGGPGIPPPPPGMGMPPPPPFG 147
|
|
| Pro-rich |
pfam15240 |
Proline-rich protein; This family includes several eukaryotic proline-rich proteins. |
53-215 |
1.42e-06 |
|
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
Pssm-ID: 464580 [Multi-domain] Cd Length: 167 Bit Score: 49.65 E-value: 1.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 53 ASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMvHPPPPGAPMAQPPTPGvlMVHP 132
Cdd:pfam15240 9 ALLALSSAQSSSEDVSQEDSPSLISEEEGQSQQGGQGPQGPPPGGFPPQPPASDDPP-GPPPPGGPQQPPPQGG--KQKP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 133 SAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPmaHPPPPGTPMAHPPPPGTPMAHP 212
Cdd:pfam15240 86 QGPPPQGGPRPPPGKPQGPPPQGGNQQQGPPPPGKPQGPPPQGGGPPPQGGNQQGP--PPPPPGNPQGPPQRPPQPGNPQ 163
|
...
gi 257900508 213 PPP 215
Cdd:pfam15240 164 GPP 166
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
11-386 |
1.67e-06 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 52.76 E-value: 1.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 11 SSPPAEAPKPP-VYSRPTVLMRAPPASSRAPPVPWDPPPIDLQA------SLAAWQAPQPAwEAPQGQLPAPVV--PMTQ 81
Cdd:PHA03378 382 ASIPQTLPDPPtVYGRPKVFARKADLKSTKKCRAIVTDPSVIKAieeehrKKKAARTEQPR-ATPHSQAPTVVLhrPPTQ 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 82 -------PPALGGPIVPAPPLGGP------MGKPPTPGV----------------------LMVHPPPPGAPMAQPPTPG 126
Cdd:PHA03378 461 plegptgPLSVQAPLEPWQPLPHPqvtpviLHQPPAQGVqahgsmldllekddedmeqrvmATLLPPSPPQPRAGRRAPC 540
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 127 VLMVH---------PSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPP---- 193
Cdd:PHA03378 541 VYTEDldiesdepaSTEPVHDQLLPAPGLGPLQIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEPPTTQSHIPetsa 620
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 194 PPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQpltPGVLMVQPAAPGAPMVQPPPAAMMTQPQP 273
Cdd:PHA03378 621 PRQWPMPLRPIPMRPLRMQPITFNVLVFPTPHQPPQVEITPYKPTWTQ---IGHIPYQPSPTGANTMLPIQWAPGTMQPP 697
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 274 SGAP--MAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQV 351
Cdd:PHA03378 698 PRAPtpMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQ 777
|
410 420 430
....*....|....*....|....*....|....*
gi 257900508 352 PQgPQAPPAQLATPPGWQATSPGWQATQQGWQATP 386
Cdd:PHA03378 778 PP-PQAPPAPQQRPRGAPTPQPPPQAGPTSMQLMP 811
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
177-305 |
1.97e-06 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 52.38 E-value: 1.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 177 TPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPP---APgvlmaqpltPGVLMVQPA 253
Cdd:PTZ00395 412 AGYSNPGNSNPGYNNAPNSNTPYNNPPNSNTPYSNPPNSNPPYSNLPYSNTPYSNAPlsnAP---------PSSAKDHHS 482
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 257900508 254 APGAPM----VQPPPAAMMTQPQPSGAPMAKPPGPGVlmiHPPGARAPMTQPPASG 305
Cdd:PTZ00395 483 AYHAAYqhraANQPAANLPTANQPAANNFHGAAGNSV---GNPFASRPFGSAPYGG 535
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
9-264 |
1.97e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 52.16 E-value: 1.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 9 GDSSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPppidlqASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGP 88
Cdd:PRK07003 364 GGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTA------VTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATAD 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 89 IVPAPPLGGPMGKPPTPGVLMVhPPPPGAPMAQPPTPGVLMVHP--SAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPG 166
Cdd:PRK07003 438 RGDDAADGDAPVPAKANARASA-DSRCDERDAQPPADSGSASAPasDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAA 516
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 167 TPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHP-----------------PPPGTPMAHPPPPGTPMAHPPPPGTPM 229
Cdd:PRK07003 517 SREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAAldvlrnagmrvssdrgaRAAAAAKPAAAPAAAPKPAAPRVAVQV 596
|
250 260 270
....*....|....*....|....*....|....*
gi 257900508 230 AQPPAPGVLMAQPLTPGvlmvQPAAPGAPMVQPPP 264
Cdd:PRK07003 597 PTPRARAATGDAPPNGA----ARAEQAAESRGAPP 627
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
131-222 |
2.09e-06 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 52.38 E-value: 2.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 131 HPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPP----PPGTPMAHPPPPGTPMAHpPPPG 206
Cdd:PTZ00395 416 NPGNSNPGYNNAPNSNTPYNNPPNSNTPYSNPPNSNPPYSNLPYSNTPYSNAPlsnaPPSSAKDHHSAYHAAYQH-RAAN 494
|
90
....*....|....*.
gi 257900508 207 TPMAHPPPPGTPMAHP 222
Cdd:PTZ00395 495 QPAANLPTANQPAANN 510
|
|
| EntF2 |
COG3319 |
Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase ... |
126-690 |
2.13e-06 |
|
Thioesterase domain of type I polyketide synthase or non-ribosomal peptide synthetase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442548 [Multi-domain] Cd Length: 855 Bit Score: 52.40 E-value: 2.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 126 GVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPP 205
Cdd:COG3319 47 LVALAALALAALALAALLAVALLAAALALAALAALAALALALAAAAAALLLAALALLLALLAALALALLALLLAALLLAL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 206 GTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPG 285
Cdd:COG3319 127 AALAAAAAAAALAAAAAAAAALAAAAGLGGGGGGAGVLVLVLAALLALLLAALLALALALAALLLLALAAALALALLLLL 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 286 VLMIHPPGARAPMTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATP 365
Cdd:COG3319 207 ALLLLLLLLLALLLLLLLALLAAAALLALLLALLLLLLAALLLLLALALLLLLALLLLLGLLALLLALLLLLALLLLAAA 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 366 PGWQATSPGWQATQQGWQATPLTWQTTQVTWQAPAVTWQVPPPMRQGPPPIRPGPPPIRPGPPPVRQAPPLIRQAPPVIR 445
Cdd:COG3319 287 AALAAGGTATTAAVTTTAAAAAPGVAGALGPIGGGPGLLVLLVLLVLLLPLLLGVGGGGGGGGGGGGAGGLAGRGLRAAA 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 446 QAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPPLWQALPPPPPLRQ 525
Cdd:COG3319 367 ALRDPAGAGARGRLRRGGDRGRRLGGGLLLGLGRLRLQRLRRGLREELEEAEAALAEAAAVAAAVAAAAAAAAAAAALAA 446
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 526 APQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAvhcpsiiwQAPKGQPPVPHEIPTSME 605
Cdd:COG3319 447 AVVAAAALAAAALLLLLLLLLLPPPLPPALLLLLLLLLLLLLAALLLAAAAPAA--------AAAAAAAPAPAAALELAL 518
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 606 FQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQLPPQQAQASGPQAEVPTLPLQPS 685
Cdd:COG3319 519 ALLLLLLLGLGLVGDDDDFFGGGGGSLLALLLLLLLLALLLRLLLLLALLLAPTLAALAAALAAAAAAAALSPLVPLRAG 598
|
....*
gi 257900508 686 WQAPP 690
Cdd:COG3319 599 GSGPP 603
|
|
| Drf_FH1 |
pfam06346 |
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs) ... |
61-226 |
2.26e-06 |
|
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues.
Pssm-ID: 461881 [Multi-domain] Cd Length: 157 Bit Score: 48.71 E-value: 2.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 61 PQPAWEAPQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPgvlmvhpPPPGAPMAQPPtpgvlmvhPSAPGAPMA 140
Cdd:pfam06346 5 PLPGDSSTIPLPPGACIPTPPPLPGGGGPPPPPPLPGSAAIPPPP-------PLPGGTSIPPP--------PPLPGAASI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 141 HPPPPGTPMSHPPPPgtpmahPPPPGTPMAHPPPPGTP-MVHPPPPGTPMahPPPPGTPmAHPPPPGTPMAHPPPPGTPM 219
Cdd:pfam06346 70 PPPPPLPGSTGIPPP------PPLPGGAGIPPPPPPLPgGAGVPPPPPPL--PGGPGIP-PPPPFPGGPGIPPPPPGMGM 140
|
....*..
gi 257900508 220 AHPPPPG 226
Cdd:pfam06346 141 PPPPPFG 147
|
|
| SOBP |
pfam15279 |
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual ... |
92-292 |
2.52e-06 |
|
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual disability. It carries a zinc-finger of the zf-C2H2 type at the N-terminus, and a highly characteriztic C-terminal PhPhPhPhPhPh motif. The deduced 873-amino acid protein contains an N-terminal nuclear localization signal (NLS), followed by 2 FCS-type zinc finger motifs, a proline-rich region (PR1), a putative RNA-binding motif region, and a C-terminal NLS embedded in a second proline-rich motif. SOBP is expressed in various human tissues, including developing mouse brain at embryonic day 14. In postnatal and adult mouse brain SOBP is expressed in all neurons, with intense staining in the limbic system. Highest expression is in layer V cortical neurons, hippocampus, pyriform cortex, dorsomedial nucleus of thalamus, amygdala, and hypothalamus. Postnatal expression of SOBP in the limbic system corresponds to a time of active synaptogenesis. the family is also referred to as Jackson circler, JXC1. In seven affected siblings from a consanguineous Israeli Arab family with mental retardation, anterior maxillary protrusion, and strabismus mutations were found in this protein.
Pssm-ID: 464609 [Multi-domain] Cd Length: 325 Bit Score: 50.97 E-value: 2.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 92 APPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMshPPPPGTPMAHPPPPGTPMAH 171
Cdd:pfam15279 82 SASPASTRSESVSPGPSSSASPSSSPTSSNSSKPLISVASSSKLLAPKPHEPPSLPPP--PLPPKKGRRHRPGLHPPLGR 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 172 PP-PPGTPMVHPPPPGTPMAHPPPPGTP--MAH---PPPPGTPMAHPPPPGTPMAHPPPPGT-PMAQPPAPGVLMAQPLT 244
Cdd:pfam15279 160 PPgSPPMSMTPRGLLGKPQQHPPPSPLPafMEPssmPPPFLRPPPSIPQPNSPLSNPMLPGIgPPPKPPRNLGPPSNPMH 239
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 257900508 245 PGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPP 292
Cdd:pfam15279 240 RPPFSPHHPPPPPTPPGPPPGLPPPPPRGFTPPFGPPFPPVNMMPNPP 287
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
56-176 |
2.66e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 51.64 E-value: 2.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 56 AAWQAPQPAWEAPQGQLPAPVVPMTQPPAlggpivPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPgvlmvHPSAP 135
Cdd:PRK14951 386 AAAPAAAPVAQAAAAPAPAAAPAAAASAP------AAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAP-----APPAQ 454
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 257900508 136 GAPMAHPPPPGTPmshpPPPGTPMAHPPPPGTPMAHPPPPG 176
Cdd:PRK14951 455 AAPETVAIPVRVA----PEPAVASAAPAPAAAPAAARLTPT 491
|
|
| Pro-rich |
pfam15240 |
Proline-rich protein; This family includes several eukaryotic proline-rich proteins. |
112-245 |
2.69e-06 |
|
Proline-rich protein; This family includes several eukaryotic proline-rich proteins.
Pssm-ID: 464580 [Multi-domain] Cd Length: 167 Bit Score: 48.88 E-value: 2.69e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 112 PPPPGAPMAQPPTPGVLMVHPSAPGAPMAhPPPPGTPMSHPPPPGTPMAHPPPPgtPMAHPPPPGTPMVHPPPPGTPMAH 191
Cdd:pfam15240 38 QSQQGGQGPQGPPPGGFPPQPPASDDPPG-PPPPGGPQQPPPQGGKQKPQGPPP--QGGPRPPPGKPQGPPPQGGNQQQG 114
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 257900508 192 PPPPGTPMAHPPPPGTPmahPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTP 245
Cdd:pfam15240 115 PPPPGKPQGPPPQGGGP---PPQGGNQQGPPPPPPGNPQGPPQRPPQPGNPQGP 165
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
243-608 |
2.94e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 51.91 E-value: 2.94e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 243 LTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVlmihPPGARAPMTQPPASGAPMAQPAAPPAQPMAPP 322
Cdd:PRK07764 385 LGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAA----PQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAA 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 323 AQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPG----------W--------QATSPGWQATQQGWQA 384
Cdd:PRK07764 461 APSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGaddaatlrerWpeilaavpKRSRKTWAILLPEATV 540
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 385 TPLTWQTTQVTWQAPA-----------------------VTWQVPPPMRQGPPPIRPGPPPIRPGPPPVRQAPPLIRQAP 441
Cdd:PRK07764 541 LGVRGDTLVLGFSTGGlarrfaspgnaevlvtalaeelgGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAA 620
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 442 PVIRQAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPqvlATQPPLWQALPPPP 521
Cdd:PRK07764 621 PAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPP---APAPAAPAAPAGAA 697
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 522 PLRQAPQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPSIIWQAPKGQPPVPHEIP 601
Cdd:PRK07764 698 PAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPS 777
|
....*..
gi 257900508 602 TSMEFQE 608
Cdd:PRK07764 778 PPSEEEE 784
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
112-297 |
3.52e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 51.39 E-value: 3.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 112 PPPPGAPMAQP---PTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTP 188
Cdd:PRK07003 367 APGGGVPARVAgavPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGD 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 189 MAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAqppapgvlMAQPLTPGVLMVQPAAPGAPMVQPPPAAmm 268
Cdd:PRK07003 447 APVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDA--------AFEPAPRAAAPSAATPAAVPDARAPAAA-- 516
|
170 180
....*....|....*....|....*....
gi 257900508 269 tqPQPSGAPMAKPPGPGVLMIHPPGARAP 297
Cdd:PRK07003 517 --SREDAPAAAAPPAPEARPPTPAAAAPA 543
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
118-267 |
4.89e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 51.02 E-value: 4.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 118 PMAQPPTPGVLMV-------HPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTP-- 188
Cdd:PRK07994 340 PLAPDRRMGVEMTllrmlafHPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPEtt 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 189 --------------MAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAA 254
Cdd:PRK07994 420 sqllaarqqlqraqGATKAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKA 499
|
170
....*....|...
gi 257900508 255 PGAPMVQPPPAAM 267
Cdd:PRK07994 500 LKKALEHEKTPEL 512
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
78-367 |
5.51e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 50.94 E-value: 5.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 78 PMTQPPALGGPiVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGT 157
Cdd:PHA03307 20 FFPRPPATPGD-AADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 158 PMAHPPPPGTPMAHPPPPgtpmvhpPPPGTPMAHPPPPgTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGV 237
Cdd:PHA03307 99 SPAREGSPTPPGPSSPDP-------PPPTPPPASPPPS-PAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSR 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 238 LMAQPLTpgvlMVQPAAPGAPmvqPPPAAMMTQPQPSGAPmAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAAPPAQ 317
Cdd:PHA03307 171 QAALPLS----SPEETARAPS---SPPAEPPPSTPPAAAS-PRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSS 242
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 257900508 318 PMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPG 367
Cdd:PHA03307 243 ESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPR 292
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
144-234 |
5.89e-06 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 51.04 E-value: 5.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 144 PPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPmvhPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPP 223
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAP---APPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVE 114
|
90
....*....|.
gi 257900508 224 PPGTPMAQPPA 234
Cdd:PRK12270 115 DEVTPLRGAAA 125
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
133-305 |
6.88e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 50.62 E-value: 6.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 133 SAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGtpmahPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHP 212
Cdd:PRK07003 366 GAPGGGVPARVAGAVPAPGARAAAAVGASAVPAV-----TAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGD 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 213 PPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLM---- 288
Cdd:PRK07003 441 DAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAsred 520
|
170
....*....|....*...
gi 257900508 289 -IHPPGARAPMTQPPASG 305
Cdd:PRK07003 521 aPAAAAPPAPEARPPTPA 538
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
61-240 |
7.39e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 50.71 E-value: 7.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 61 PQPAWEAPQGQLPAPV-------VPMTQPPALGGPivPAPPLGGPMGKPPTPGVLMVHPP--------PPGAPMAQPPT- 124
Cdd:PHA03247 282 PEAAAPNGAAAPPDGVwgaalagAPLALPAPPDPP--PPAPAGDAEEEDDEDGAMEVVSPlprprqhyPLGFPKRRRPTw 359
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 125 -PGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPP 203
Cdd:PHA03247 360 tPPSSLEDLSAGRHHPKRASLPTRKRRSARHAATPFARGPGGDDQTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAE 439
|
170 180 190
....*....|....*....|....*....|....*..
gi 257900508 204 PPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMA 240
Cdd:PHA03247 440 PGSDDGPAPPPERQPPAPATEPAPDDPDDATRKALDA 476
|
|
| Drf_FH1 |
pfam06346 |
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs) ... |
122-273 |
7.93e-06 |
|
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues.
Pssm-ID: 461881 [Multi-domain] Cd Length: 157 Bit Score: 47.17 E-value: 7.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 122 PPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGtpmahPPPPGTPMVHPPPPGTPMAH-PPPPGTPMA 200
Cdd:pfam06346 4 PPLPGDSSTIPLPPGACIPTPPPLPGGGGPPPPPPLPGSAAIPPP-----PPLPGGTSIPPPPPLPGAASiPPPPPLPGS 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 257900508 201 HPPPPGTPMahPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPgvlmvQPAAPGAPMVQPPPAAMMTQPQP 273
Cdd:pfam06346 79 TGIPPPPPL--PGGAGIPPPPPPLPGGAGVPPPPPPLPGGPGIPP-----PPPFPGGPGIPPPPPGMGMPPPP 144
|
|
| BimA_second |
NF040983 |
trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia ... |
112-212 |
1.02e-05 |
|
trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia intracellular motility A), WP_004266405.1-like proteins in Burkholderia mallei or B. pseudomallei. The term BimA has also been used for WP_011205626.1-like homologs that have a very different N-terminal half.
Pssm-ID: 468913 [Multi-domain] Cd Length: 382 Bit Score: 49.52 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 112 PPPPGAPMAQPPTPgvlmvhpsapgapmahPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPmah 191
Cdd:NF040983 90 PPPPPPPPPPPPPP----------------PTPPPPPPPPPPPPPPSPPPPPPPSPPPSPPPPTTTPPTRTTPSTTT--- 150
|
90 100
....*....|....*....|.
gi 257900508 192 PPPPGTPMAHPPPPGTPMAHP 212
Cdd:NF040983 151 PTPSMHPIQPTQLPSIPNATP 171
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
110-272 |
1.05e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 49.86 E-value: 1.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 110 VHPPPPGAPMAQPPTPgvlmVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPM 189
Cdd:PRK07994 369 EVPPQSAAPAASAQAT----AAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSEPA 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 190 AHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPgaPMVQPPPAAMMT 269
Cdd:PRK07994 445 AASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTP--ELAAKLAAEAIE 522
|
...
gi 257900508 270 QPQ 272
Cdd:PRK07994 523 RDP 525
|
|
| SOBP |
pfam15279 |
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual ... |
59-264 |
1.18e-05 |
|
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual disability. It carries a zinc-finger of the zf-C2H2 type at the N-terminus, and a highly characteriztic C-terminal PhPhPhPhPhPh motif. The deduced 873-amino acid protein contains an N-terminal nuclear localization signal (NLS), followed by 2 FCS-type zinc finger motifs, a proline-rich region (PR1), a putative RNA-binding motif region, and a C-terminal NLS embedded in a second proline-rich motif. SOBP is expressed in various human tissues, including developing mouse brain at embryonic day 14. In postnatal and adult mouse brain SOBP is expressed in all neurons, with intense staining in the limbic system. Highest expression is in layer V cortical neurons, hippocampus, pyriform cortex, dorsomedial nucleus of thalamus, amygdala, and hypothalamus. Postnatal expression of SOBP in the limbic system corresponds to a time of active synaptogenesis. the family is also referred to as Jackson circler, JXC1. In seven affected siblings from a consanguineous Israeli Arab family with mental retardation, anterior maxillary protrusion, and strabismus mutations were found in this protein.
Pssm-ID: 464609 [Multi-domain] Cd Length: 325 Bit Score: 49.04 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 59 QAPQPAWEAPQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGvlmvHPPPPGAPMAQPPTpgvLMVHPSAPGAP 138
Cdd:pfam15279 105 SSPTSSNSSKPLISVASSSKLLAPKPHEPPSLPPPPLPPKKGRRHRPG----LHPPLGRPPGSPPM---SMTPRGLLGKP 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 139 MAHPPPPGTPM-----SHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPP-----PGTPMAHPP-----PPGTPMAHPP 203
Cdd:pfam15279 178 QQHPPPSPLPAfmepsSMPPPFLRPPPSIPQPNSPLSNPMLPGIGPPPKPPrnlgpPSNPMHRPPfsphhPPPPPTPPGP 257
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 257900508 204 PPGtPMAHPPPPGTPMAHPPPpgtpmaqPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPP 264
Cdd:pfam15279 258 PPG-LPPPPPRGFTPPFGPPF-------PPVNMMPNPPEMNFGLPSLAPLVPPVTVLVPYP 310
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
117-212 |
1.43e-05 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 49.69 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 117 APMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPP----PPGTPMVHPPPPGTPMAHp 192
Cdd:PTZ00395 412 AGYSNPGNSNPGYNNAPNSNTPYNNPPNSNTPYSNPPNSNPPYSNLPYSNTPYSNAPlsnaPPSSAKDHHSAYHAAYQH- 490
|
90 100
....*....|....*....|
gi 257900508 193 PPPGTPMAHPPPPGTPMAHP 212
Cdd:PTZ00395 491 RAANQPAANLPTANQPAANN 510
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
67-302 |
1.87e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 49.08 E-value: 1.87e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 67 APQGQLPAPV---VPMTQPPALGGPIVPAPPLGGPMGKPPT-----PGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAP 138
Cdd:PRK07003 367 APGGGVPARVagaVPAPGARAAAAVGASAVPAVTAVTGAAGaalapKAAAAAAATRAEAPPAAPAPPATADRGDDAADGD 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 139 MAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPP--PGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPG 216
Cdd:PRK07003 447 APVPAKANARASADSRCDERDAQPPADSGSASAPASdaPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAA 526
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 217 TPMAHPPPPGTPMAQPPAPGVLMAQPL----------------TPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAK 280
Cdd:PRK07003 527 PPAPEARPPTPAAAAPAARAGGAAAALdvlrnagmrvssdrgaRAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATG 606
|
250 260
....*....|....*....|..
gi 257900508 281 PPGPGVLMIHPPGARAPMTQPP 302
Cdd:PRK07003 607 DAPPNGAARAEQAAESRGAPPP 628
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
117-256 |
1.88e-05 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 49.03 E-value: 1.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 117 APMAQPPTPgvlMVHPSAPGAPMAHPPPPGTPMSHPP---PPGTPMahpPPPGTPMAHPPPPGtpmvhpPPPGTPMAHPP 193
Cdd:TIGR01628 380 PRMRQLPMG---SPMGGAMGQPPYYGQGPQQQFNGQPlgwPRMSMM---PTPMGPGGPLRPNG------LAPMNAVRAPS 447
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 257900508 194 PPGTPMAHPPPpgtPMAHPPPPGTpMAHPPPPGTPmAQPPAPGVLMAQPLTPGVLmvQPAAPG 256
Cdd:TIGR01628 448 RNAQNAAQKPP---MQPVMYPPNY-QSLPLSQDLP-QPQSTASQGGQNKKLAQVL--ASATPQ 503
|
|
| KLF1_2_4_N-like |
cd22056 |
N-terminal domain of Kruppel-like factors with similarity to the N-terminal domains of ... |
87-248 |
1.94e-05 |
|
N-terminal domain of Kruppel-like factors with similarity to the N-terminal domains of Kruppel-like factor (KLF)1, KLF2, and KLF4; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specifity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domains of an unknown subfamily of KLFs, predominantly found in fish, related to the N-terminal domains of KLF1, KLF2, and KLF4.
Pssm-ID: 409231 [Multi-domain] Cd Length: 339 Bit Score: 48.12 E-value: 1.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 87 GPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPG-----------VLMVhpSAPGAPMAHPPPPGTPMSHPPPP 155
Cdd:cd22056 143 GESSPDSAGKARDGREYTELRALPTAPPAHQPATSPPPLGykiktepveqsCMMA--AGGGGFMGQQKPKHQMHSVHPQA 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 156 GTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPpgTPMAQPPAP 235
Cdd:cd22056 221 FTHHQAAGPGALQGRGGRGGPDCHLLHSSHHHHHHHHLQYQYMNAPYPPHYAHQGAPQFHGQYSVFREP--MRVHHQGHP 298
|
170
....*....|...
gi 257900508 236 GVLMAQPLTPGVL 248
Cdd:cd22056 299 GSMLTPPSSPPLL 311
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
163-233 |
1.99e-05 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 48.00 E-value: 1.99e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 163 PPPGTPMAHPPPPGTPmvhPPPPGTPMAHPPPPGTPM-AHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPP 233
Cdd:pfam07174 45 PPPPSTATAPPAPPPP---PPAPAAPAPPPPPAAPNApNAPPPPADPNAPPPPPADPNAPPPPAVDPNAPEP 113
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
253-398 |
2.51e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 48.56 E-value: 2.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 253 AAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAP- 331
Cdd:PRK14951 369 AAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALa 448
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 257900508 332 -----QAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPGWQATSPGWQAT-QQGWQATPLTWQTTQVTWQA 398
Cdd:PRK14951 449 pappaQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDVWHATvQQLAAAEAITALARELALQS 521
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
74-277 |
2.85e-05 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 48.28 E-value: 2.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 74 APVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGvlmvhPPPPGAPMAQPPTPGVLMV----HPSAPGAPMAHPPPPGTPM 149
Cdd:PRK14086 67 APIISETLSRELGRPIRIAITVDPSAGEPAPPP-----PHARRTSEPELPRPGRRPYegygGPRADDRPPGLPRQDQLPT 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 150 SHPPPP-----GTPMAHPPPPGTPMAHPPPPGTPmvhPPPPGTPMAHPPPPGTPMAHPPPPGTPM--AHPPPPGTPMAHP 222
Cdd:PRK14086 142 ARPAYPayqqrPEPGAWPRAADDYGWQQQRLGFP---PRAPYASPASYAPEQERDREPYDAGRPEydQRRRDYDHPRPDW 218
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 223 PPPG-----TPMAQPPAPGVLMAQPLTPGVlmvqPAAPGAPMVQPPPAAMMTQPQPSGAP 277
Cdd:PRK14086 219 DRPRrdrtdRPEPPPGAGHVHRGGPGPPER----DDAPVVPIRPSAPGPLAAQPAPAPGP 274
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
133-223 |
2.94e-05 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 47.61 E-value: 2.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 133 SAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPmahPPPPGTPMVHPPPPGTPM-AHPPPPGTPMAHPPPPGTPMAH 211
Cdd:pfam07174 25 GASAVAVALPAVAHADPEPAPPPPSTATAPPAPPPP---PPAPAAPAPPPPPAAPNApNAPPPPADPNAPPPPPADPNAP 101
|
90
....*....|..
gi 257900508 212 PPPPGTPMAHPP 223
Cdd:pfam07174 102 PPPAVDPNAPEP 113
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
136-219 |
2.99e-05 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 48.73 E-value: 2.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 136 GAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPP 215
Cdd:PRK12270 37 GPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDE 116
|
....
gi 257900508 216 GTPM 219
Cdd:PRK12270 117 VTPL 120
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
189-305 |
3.30e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 48.17 E-value: 3.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 189 MAHPPPPGTPMAHPPPPGTPmaHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMM 268
Cdd:PRK14951 362 LAFKPAAAAEAAAPAEKKTP--ARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPA 439
|
90 100 110
....*....|....*....|....*....|....*..
gi 257900508 269 TQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASG 305
Cdd:PRK14951 440 AAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAA 476
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
73-235 |
5.24e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 47.55 E-value: 5.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 73 PAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGvlmVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHP 152
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPP---QAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATK 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 153 PPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPgtPMAQP 232
Cdd:PRK07994 438 AKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTP--ELAAK 515
|
...
gi 257900508 233 PAP 235
Cdd:PRK07994 516 LAA 518
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
15-305 |
5.31e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.86 E-value: 5.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 15 AEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPAlGGPIVPAPP 94
Cdd:PHA03307 60 AACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPS-PAPDLSEML 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 95 LGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPP 174
Cdd:PHA03307 139 RPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASAS 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 175 PGTPM------------------------------VHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPP 224
Cdd:PHA03307 219 SPAPApgrsaaddagasssdssssessgcgwgpenECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSP 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 225 ----PGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQ 300
Cdd:PHA03307 299 spssPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSP 378
|
....*
gi 257900508 301 PPASG 305
Cdd:PHA03307 379 AASAG 383
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
68-215 |
5.47e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 47.55 E-value: 5.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 68 PQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAP--MAQPPTPGVLMVHPSAPGAPMAHPPPP 145
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPavPLPETTSQLLAARQQLQRAQGATKAKK 440
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 146 GTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPP 215
Cdd:PRK07994 441 SEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTP 510
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
158-243 |
5.54e-05 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 47.58 E-value: 5.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 158 PMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPmahPPPPGTPMAHPPPPGTPMAQPPAPGV 237
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAA---AAAAAAAPAAPPAAAAAAAPAAAAVE 114
|
....*.
gi 257900508 238 LMAQPL 243
Cdd:PRK12270 115 DEVTPL 120
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
50-274 |
8.38e-05 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 46.84 E-value: 8.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 50 DLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPAlGGPIVPAPPLGGPMG-KPPTPGVLMVHPPPPGAPMAQPPTPGVL 128
Cdd:PLN03209 318 ELLAKIPSQRVPPKESDAADGPKPVPTKPVTPEAP-SPPIEEEPPQPKAVVpRPLSPYTAYEDLKPPTSPIPTPPSSSPA 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 129 MVH-------PSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPP--PGTPM 199
Cdd:PLN03209 397 SSKsvdavakPAEPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPYARYEDLKPPTSPSPTAPTGVSPSVSSTSsvPAVPD 476
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 257900508 200 AHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQP--PAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPS 274
Cdd:PLN03209 477 TAPATAATDAAAPPPANMRPLSPYAVYDDLKPPtsPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQPKPR 553
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
152-227 |
8.44e-05 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 43.14 E-value: 8.44e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 257900508 152 PPPPGTPMAHPP--PPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAhPPPPGTPMAHPPPPGT 227
Cdd:pfam12526 31 PPESAHPDPPPPvgDPRPPVVDTPPPVSAVWVLPPPSEPAAPEPDLVPPVTGPAGPPSPLA-PPAPAQKPPLPPPRPQ 107
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
163-266 |
8.69e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 46.73 E-value: 8.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 163 PPPGTPMAHPPPPGTPMVHPPPpgTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPapgvlmaqp 242
Cdd:PRK14950 362 PVPAPQPAKPTAAAPSPVRPTP--APSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPK--------- 430
|
90 100
....*....|....*....|....
gi 257900508 243 lTPGVLMVQPAAPGAPMVQPPPAA 266
Cdd:PRK14950 431 -LTRAAIPVDEKPKYTPPAPPKEE 453
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
143-273 |
9.40e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 46.69 E-value: 9.40e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 143 PPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAhpPPPGTPMAHP 222
Cdd:PRK14971 370 SGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPV--NPPSTAPQAV 447
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 257900508 223 PPPGTPMAQPPAPgvlMAQPLTpGVLMVQPAAPGAPMVQPPPAAMMTQPQP 273
Cdd:PRK14971 448 RPAQFKEEKKIPV---SKVSSL-GPSTLRPIQEKAEQATGNIKEAPTGTQK 494
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
532-701 |
1.03e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 47.00 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 532 PAPQVQAAPQVPTAPPATQVPAA---PPAGPQVPQPVL-PAPLSAPlSAPQAVHcPSIIWQAPKGQP-PVPHEIPTSMEF 606
Cdd:PRK10263 336 PVEPVTQTPPVASVDVPPAQPTVawqPVPGPQTGEPVIaPAPEGYP-QQSQYAQ-PAVQYNEPLQQPvQPQQPYYAPAAE 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 607 QEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQLPPQQAqasgpqaevptlplqPSW 686
Cdd:PRK10263 414 QPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQE---------------PLY 478
|
170
....*....|....*
gi 257900508 687 QAPPAVLQAQPGPPV 701
Cdd:PRK10263 479 QQPQPVEQQPVVEPE 493
|
|
| KLF2_N |
cd21583 |
N-terminal domain of Kruppel-like factor 2; Kruppel-like Factor 2 (KLF2, also known as ... |
78-245 |
1.09e-04 |
|
N-terminal domain of Kruppel-like factor 2; Kruppel-like Factor 2 (KLF2, also known as Krueppel-like factor 2 or lung Kruppel-like Factor/LKLF) is a protein that, in humans, is encoded by the KLF2 gene on chromosome 19. It has been implicated in a variety of biochemical processes in the human body, including lung development, embryonic erythropoiesis, epithelial integrity, T-cell viability, and adipogenesis. KLF proteins KLF1, KLF2, KLF4, KLF5, KLF6, and KLF7 are transcriptional activators. KLF2 belongs to a family of proteins called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF2, which is related to the N-terminal domains of KLF1 and KLF4.
Pssm-ID: 409229 [Multi-domain] Cd Length: 299 Bit Score: 45.79 E-value: 1.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 78 PMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMVH--PPPPGAPMAQPPTPGVLMVHPSAPGAPM-----AHPPPPGTPMS 150
Cdd:cd21583 72 SAGAAGGGYYGSLPEPAAPYSASNPPGAYSVPEQgsPPPPYSSSLMAELLRDSDSDYGPSNSIQgrflvSSAFFPRQDDP 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 151 HPPPPGTPMAHPPPPGTP-----------------MAHPP------PPGTPMVHPP-PPGTPMAHPPPPGTPMAHPPPPG 206
Cdd:cd21583 152 DSIKVEPSMDSYGPVMGMvpqscpkikqegnvscmMSFEQprlansPQAAGSMTPPlSPDDLMASECQQQMMCSPSFPQP 231
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 257900508 207 TPMAHPPPPGTPMAHPPPPGTPM------AQPPAPGVLmaqpLTP 245
Cdd:cd21583 232 HHPHYPPPPQPPLQYQSPHQFGLfedglpLQPSAQRVL----LTP 272
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
51-155 |
1.16e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 46.34 E-value: 1.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 51 LQASLAAWQAPQPAweAPQGQLPAPVVPMtqpPALGGPIVPAPPLGGPmGKPPTPGVLmvHPPPPGAPMAQPPTPGvlmV 130
Cdd:PRK14950 356 IEALLVPVPAPQPA--KPTAAAPSPVRPT---PAPSTRPKAAAAANIP-PKEPVRETA--TPPPVPPRPVAPPVPH---T 424
|
90 100
....*....|....*....|....*
gi 257900508 131 HPSAPGAPMAHPPPPGTPMSHPPPP 155
Cdd:PRK14950 425 PESAPKLTRAAIPVDEKPKYTPPAP 449
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
15-224 |
1.18e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 46.38 E-value: 1.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 15 AEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAA---WQAPQPAWEAPQGQLPAPVVPMTQPPALGGPIVP 91
Cdd:PRK07003 395 AVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADrgdDAADGDAPVPAKANARASADSRCDERDAQPPADS 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 92 APPLGGPMGKPPTPgvlMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPP-------- 163
Cdd:PRK07003 475 GSASAPASDAPPDA---AFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAaraggaaa 551
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 164 -------------------PPGTPMAHPPPPGTPMVHPPPPGTPMahpPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPP 224
Cdd:PRK07003 552 aldvlrnagmrvssdrgarAAAAAKPAAAPAAAPKPAAPRVAVQV---PTPRARAATGDAPPNGAARAEQAAESRGAPPP 628
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
151-270 |
1.37e-04 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 46.11 E-value: 1.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 151 HPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPgtPMAHPPPPGTPmAHPPPPGTPMAHPPPPGTPMAhppPPGTPMA 230
Cdd:PRK06995 52 APPAAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPW--LVEHAKRLTAQ-REQLVARAAAPAAPEAQAPAA---PAERAAA 125
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 257900508 231 QPPAPGVLMAQPLTPGVLMVQPAAPG-APMVQPPPAAMMTQ 270
Cdd:PRK06995 126 ENAARRLARAAAAAPRPRVPADAAAAvADAVKARIERIVND 166
|
|
| BimA_second |
NF040983 |
trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia ... |
192-253 |
1.42e-04 |
|
trimeric autotransporter actin-nucleating factor BimA; This HMM describes BimA (Burkholderia intracellular motility A), WP_004266405.1-like proteins in Burkholderia mallei or B. pseudomallei. The term BimA has also been used for WP_011205626.1-like homologs that have a very different N-terminal half.
Pssm-ID: 468913 [Multi-domain] Cd Length: 382 Bit Score: 45.66 E-value: 1.42e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 192 PPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPA 253
Cdd:NF040983 93 PPPPPPPPPPPPTPPPPPPPPPPPPPPSPPPPPPPSPPPSPPPPTTTPPTRTTPSTTTPTPS 154
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
201-296 |
1.48e-04 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 45.73 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 201 HPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGV--LMVQPAAPGAPMVQPPPA---AMMTQPQPSG 275
Cdd:PRK06995 52 APPAAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPWLVEHAKRLTAQReqLVARAAAPAAPEAQAPAApaeRAAAENAARR 131
|
90 100
....*....|....*....|.
gi 257900508 276 APMAKPPGPGVLMIHPPGARA 296
Cdd:PRK06995 132 LARAAAAAPRPRVPADAAAAV 152
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
132-209 |
1.53e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 46.42 E-value: 1.53e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 257900508 132 PSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPM 209
Cdd:PRK12270 43 APTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEVTPL 120
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
439-705 |
1.61e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 46.00 E-value: 1.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 439 QAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPVirqAPPVIRQAPPVIRQAPPlIRQAPPPIRPAPQVLATQPPLWQALP 518
Cdd:PRK07003 371 GVPARVAGAVPAPGARAAAAVGASAVPAVTAVT---GAAGAALAPKAAAAAAA-TRAEAPPAAPAPPATADRGDDAADGD 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 519 PPPPLRQAPQARlPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPSIIWQAPKGQPPVPH 598
Cdd:PRK07003 447 APVPAKANARAS-ADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAA 525
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 599 EIPTSmefqevqQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQLPPQQAqASGPQAEVP 678
Cdd:PRK07003 526 APPAP-------EARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPA-APRVAVQVP 597
|
250 260
....*....|....*....|....*..
gi 257900508 679 TlPLQPSWQAPPAVLQAQPGPPVAAAN 705
Cdd:PRK07003 598 T-PRARAATGDAPPNGAARAEQAAESR 623
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
69-191 |
1.65e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 45.95 E-value: 1.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 69 QGQLPAPVVPMTQPPAlggpivpAPPLGGPMGKPP--TPGVLMVHPPPPGAPMAQPPTPGVLMvhPSAPGAPM--AHPPP 144
Cdd:TIGR01628 372 QDQFMQLQPRMRQLPM-------GSPMGGAMGQPPyyGQGPQQQFNGQPLGWPRMSMMPTPMG--PGGPLRPNglAPMNA 442
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 257900508 145 PGTpmshPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAH 191
Cdd:TIGR01628 443 VRA----PSRNAQNAAQKPPMQPVMYPPNYQSLPLSQDLPQPQSTAS 485
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
174-400 |
1.69e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 46.02 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 174 PPGTPMVHPPPPGTPMAHPPPPgtpmAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPltpgvlmvQPA 253
Cdd:PRK12323 373 GPATAAAAPVAQPAPAAAAPAA----AAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAAR--------QAS 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 254 APGAPMVQPPPAAMMTQPqpsgAPMAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQA 333
Cdd:PRK12323 441 ARGPGGAPAPAPAPAAAP----AAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDA 516
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 257900508 334 QPLILQIQSQV--IRAPPQVPQGPQAPPAQLATPPGWQATSPGWQATQQGWQATPLTWQTTQVTWQAPA 400
Cdd:PRK12323 517 APAGWVAESIPdpATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALA 585
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
376-579 |
1.74e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 46.02 E-value: 1.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 376 QATQQGWQATPLTWQTTQVTWQAPAVTWQVPPPMRQGPPPIRPGPPPIRPGPPPVRQAPPLIRQAPPVIRQAPPVIRQAP 455
Cdd:PRK12323 364 RPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARG 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 456 PVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPiRPAPQVLATQPPLWQALPPPPPLRQAPQARLPAPQ 535
Cdd:PRK12323 444 PGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAA-APAPADDDPPPWEELPPEFASPAPAQPDAAPAGWV 522
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 257900508 536 VQAAPQVPTAPPATQVPAA--PPAGPQVPQPVLPAPLSAPLSAPQA 579
Cdd:PRK12323 523 AESIPDPATADPDDAFETLapAPAAAPAPRAAAATEPVVAPRPPRA 568
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
462-602 |
1.91e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 45.63 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 462 PAVIRQAPPVIRQ--APPVIRQAPPVIRQAPplirqAPPPIRPAPQVLATQPPLWQALPPPPPLRQAPQARLPAPQVQAA 539
Cdd:PRK07994 361 PAAPLPEPEVPPQsaAPAASAQATAAPTAAV-----APPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGA 435
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 257900508 540 PQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPSIIWQAPKGQPPVPHEIPT 602
Cdd:PRK07994 436 TKAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPK 498
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
538-697 |
2.07e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 45.80 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 538 AAPQVPTAPPATQVPAAPPAGPQVPQPVLP-----------APLSAPLSAPQAVHCPSIIwQAPKGQPP--VPHEIPTSM 604
Cdd:pfam09770 166 APKKAAAPAPAPQPAAQPASLPAPSRKMMSleeveaamraqAKKPAQQPAPAPAQPPAAP-PAQQAQQQqqFPPQIQQQQ 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 605 EFQEvQQTQALAWQAQKAPTHIWQ------PLPAQEAQRQAPPLVQLEQPFQGAPPSQ--------KAVQIQLPPQQAQA 670
Cdd:pfam09770 245 QPQQ-QPQQPQQHPGQGHPVTILQrpqspqPDPAQPSIQPQAQQFHQQPPPVPVQPTQilqnpnrlSAARVGYPQNPQPG 323
|
170 180
....*....|....*....|....*..
gi 257900508 671 SGPQAEVPTLPLQPSwQAPPAVLQAQP 697
Cdd:pfam09770 324 VQPAPAHQAHRQQGS-FGRQAPIITHP 349
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
111-199 |
2.11e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 45.65 E-value: 2.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 111 HPPPPGAPMAQPPTPGvlmvhPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMA 190
Cdd:PRK12270 37 GPGSTAAPTAAAAAAA-----AAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAA 111
|
....*....
gi 257900508 191 HPPPPGTPM 199
Cdd:PRK12270 112 AVEDEVTPL 120
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
26-273 |
2.16e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 45.61 E-value: 2.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 26 PTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQL-----PAPVVPMTQPPALGGPIVPAPPLGGPMG 100
Cdd:PRK07003 360 PAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAgaalaPKAAAAAAATRAEAPPAAPAPPATADRG 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 101 KPPTPGVLMVHPPPPgAPMAQPPTPGVLMVHPSAPGAPMAHPPP--PGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTP 178
Cdd:PRK07003 440 DDAADGDAPVPAKAN-ARASADSRCDERDAQPPADSGSASAPASdaPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASR 518
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 179 MVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHP-----------------PPPGTPMAHPPPPGTPMAQPPAPGVLMAQ 241
Cdd:PRK07003 519 EDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAAldvlrnagmrvssdrgaRAAAAAKPAAAPAAAPKPAAPRVAVQVPT 598
|
250 260 270
....*....|....*....|....*....|..
gi 257900508 242 PLTPGVLMVQPAAPGAPmvqPPPAAMMTQPQP 273
Cdd:PRK07003 599 PRARAATGDAPPNGAAR---AEQAAESRGAPP 627
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
532-690 |
2.23e-04 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 45.80 E-value: 2.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 532 PAPQVQAAPQVPTAPPATQVPAAPPA-------GPQVPQPVLPAPLSAPLSAPQAVHCPSIIwqAPKGQPP-------VP 597
Cdd:PRK10811 860 EAEEVQVQPVVAEVPVAAAVEPVVSApvveavaEVVEEPVVVAEPQPEEVVVVETTHPEVIA--APVTEQPqvitesdVA 937
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 598 HEIPTSMEFQEVQQTQALAWQAQKAP--THIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQLPPQQA----QAS 671
Cdd:PRK10811 938 VAQEVAEHAEPVVEPQDETADIEEAAetAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATvehnHAT 1017
|
170 180
....*....|....*....|....*
gi 257900508 672 GPQ------AEVPTLPLQPSWQAPP 690
Cdd:PRK10811 1018 APMtrapapEYVPEAPRHSDWQRPT 1042
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
174-581 |
2.79e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.36 E-value: 2.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 174 PPGTPMVHPPPPGTPMAHPPPPGTPmahPPPPGTPMAHPPPPgtPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPA 253
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAP---APAAAAPAAAAAPA--PAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAA 460
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 254 APGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGvlmiHPPGARAPMTQPPASGAPMAQpaappaqpmappaqpmaswapQA 333
Cdd:PRK07764 461 APSAQPAPAPAAAPEPTAAPAPAPPAAPAPAA----APAAPAAPAAPAGADDAATLR---------------------ER 515
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 334 QPLILQIQSQVIRA------PPQVPQGPQAPPAQLATPpgwqaTSPGWQATQQGWQATPLTWQTTQVTWQAPAVTWQV-- 405
Cdd:PRK07764 516 WPEILAAVPKRSRKtwaillPEATVLGVRGDTLVLGFS-----TGGLARRFASPGNAEVLVTALAEELGGDWQVEAVVgp 590
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 406 -----PPPMRQGPPPIRPGPPPIRPGPPPVRQAPPLIRQAPPVIRQAPPVIRQAPPVI---RQAPAVIRQAPPVIRQAPP 477
Cdd:PRK07764 591 apgaaGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAapeHHPKHVAVPDASDGGDGWP 670
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 478 VIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPPLWQALPPPPPLRQAPQARLPA----PQVQAAPQVPTAPPATQVPA 553
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQgasaPSPAADDPVPLPPEPDDPPD 750
|
410 420
....*....|....*....|....*...
gi 257900508 554 APPAGPQVPQPVLPAPLSAPLSAPQAVH 581
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPAAAPPPSP 778
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
161-281 |
2.92e-04 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 44.96 E-value: 2.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 161 HPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPgtPMAHPPPPGTPmAHPPPPGTPMAHPPPPGTPMAQPPAPgvlMA 240
Cdd:PRK06995 52 APPAAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPW--LVEHAKRLTAQ-REQLVARAAAPAAPEAQAPAAPAERA---AA 125
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 257900508 241 QPLTPGVLMVQPAAPgAPMVQPPPAAMMTQPQPSGAPMAKP 281
Cdd:PRK06995 126 ENAARRLARAAAAAP-RPRVPADAAAAVADAVKARIERIVN 165
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
529-711 |
3.11e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 45.03 E-value: 3.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 529 ARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPV--------LPAPLSAplsapqaVHCPSIIWQAPKGQPPVPHEI 600
Cdd:pfam09770 104 RQQPAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVrtgyekykEPEPIPD-------LQVDASLWGVAPKKAAAPAPA 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 601 PtsmefqEVQQTQALAWQAQKAPTHIwQPLPAQ---EAQRQAPPLVQLEQPFQGAPPSQKAVQIQLPPQQAQASGPQAEV 677
Cdd:pfam09770 177 P------QPAAQPASLPAPSRKMMSL-EEVEAAmraQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQ 249
|
170 180 190
....*....|....*....|....*....|....*
gi 257900508 678 PTLPLQPSWQA-PPAVLQAQPGPPVAAANFPLGSA 711
Cdd:pfam09770 250 PQQPQQHPGQGhPVTILQRPQSPQPDPAQPSIQPQ 284
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
465-717 |
3.57e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 45.08 E-value: 3.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 465 IRQAPPVIRQAPPVirQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPPLWQALPPPPPLRQAPQARLPAPQVQAAPQVPT 544
Cdd:PRK10263 340 VTQTPPVASVDVPP--AQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQ 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 545 APPATQVPAAPPAGPQ-VPQPVLPAPLSAplsapqavhcpsiiWQAPKGQPPVPHEiPTSMEFQEVQQ--TQALAWQAQK 621
Cdd:PRK10263 418 QPYYAPAPEQPAQQPYyAPAPEQPVAGNA--------------WQAEEQQSTFAPQ-STYQTEQTYQQpaAQEPLYQQPQ 482
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 622 A--PTHIWQPLPAQEAQRQA-PPLVQLEQPFQGAPPSQKAVQIQLPPQQAQASGPQAEVPTLPLQPSWQAPPAVLQAQPG 698
Cdd:PRK10263 483 PveQQPVVEPEPVVEETKPArPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVS 562
|
250 260
....*....|....*....|..
gi 257900508 699 P---PVAAANFPLGSAKSLMTP 717
Cdd:PRK10263 563 PlasGVKKATLATGAAATVAAP 584
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
609-721 |
4.09e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 44.71 E-value: 4.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 609 VQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQiqlPPQQAQASGPQAEVPTLPLQPSWQA 688
Cdd:PRK14951 385 EAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAA---APAAAPAAVALAPAPPAQAAPETVA 461
|
90 100 110
....*....|....*....|....*....|...
gi 257900508 689 PPAVLQAQPGPPVAAANFPLGSAKSLMTPSGEC 721
Cdd:PRK14951 462 IPVRVAPEPAVASAAPAPAAAPAAARLTPTEEG 494
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
33-245 |
4.21e-04 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 44.53 E-value: 4.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 33 PPASSRAPPVPWDPPPIDLQASLAAWQAPQPAweAPQGQLPAPVVPMTQPPALGGPI--VPAPPLGGPMGKPPTPGVLMv 110
Cdd:PLN03209 330 PKESDAADGPKPVPTKPVTPEAPSPPIEEEPP--QPKAVVPRPLSPYTAYEDLKPPTspIPTPPSSSPASSKSVDAVAK- 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 111 hPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPP--PGTPMVHPPPPGTP 188
Cdd:PLN03209 407 -PAEPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPYARYEDLKPPTSPSPTAPTGVSPSVSSTSsvPAVPDTAPATAATD 485
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 257900508 189 MAHPPPPgTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTP 245
Cdd:PLN03209 486 AAAPPPA-NMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTAL 541
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
112-197 |
4.46e-04 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 41.22 E-value: 4.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 112 PPPPGAPMAQPPtpgvlmvhPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVhPPPPGTPMAH 191
Cdd:pfam12526 31 PPESAHPDPPPP--------VGDPRPPVVDTPPPVSAVWVLPPPSEPAAPEPDLVPPVTGPAGPPSPLA-PPAPAQKPPL 101
|
....*.
gi 257900508 192 PPPPGT 197
Cdd:pfam12526 102 PPPRPQ 107
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
9-232 |
4.64e-04 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 44.76 E-value: 4.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 9 GDSSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGP 88
Cdd:pfam03154 285 GPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIP 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 89 IVPAP-------------PLGGPMGKPPTPGV-----LMVHPPPPGAP------------MAQPPTPGVLMVHPSAPGAP 138
Cdd:pfam03154 365 QLPNPqshkhpphlsgpsPFQMNSNLPPPPALkplssLSTHHPPSAHPpplqlmpqsqqlPPPPAQPPVLTQSQSLPPPA 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 139 MAHPPPPGTPM--SHPPPPGTPMAHPPPPGTPMAHPPPPGTP----MVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHP 212
Cdd:pfam03154 445 ASHPPTSGLHQvpSQSPFPQHPFVPGGPPPITPPSGPPTSTSsampGIQPPSSASVSSSGPVPAAVSCPLPPVQIKEEAL 524
|
250 260
....*....|....*....|
gi 257900508 213 PPPGTPMAHPPPPGTPMAQP 232
Cdd:pfam03154 525 DEAEEPESPPPPPRSPSPEP 544
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
184-295 |
4.67e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 44.50 E-value: 4.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 184 PPGTPmahPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPgvlmaqpltpgvlmvQPAAPGAPMVQPP 263
Cdd:PRK12270 38 PGSTA---APTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKP---------------AAAAAAAAAPAAP 99
|
90 100 110
....*....|....*....|....*....|..
gi 257900508 264 PAammtqPQPSGAPMAKPPGPGVLMIHPPGAR 295
Cdd:PRK12270 100 PA-----AAAAAAPAAAAVEDEVTPLRGAAAA 126
|
|
| PHA03264 |
PHA03264 |
envelope glycoprotein D; Provisional |
130-257 |
4.73e-04 |
|
envelope glycoprotein D; Provisional
Pssm-ID: 223029 [Multi-domain] Cd Length: 416 Bit Score: 44.23 E-value: 4.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 130 VHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPM 209
Cdd:PHA03264 253 VVPPYFEESKGYEPPPAPSGGSPAPPGDDRPEAKPEPGPVEDGAPGRETGGEGEGPEPAGRDGAAGGEPKPGPPRPAPDA 332
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 257900508 210 AHPP--PPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGA 257
Cdd:PHA03264 333 DRPEgwPSLEAITFPPPTPATPAVPRARPVIVGTGIAAAAIACVAAAGAV 382
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
115-193 |
4.98e-04 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 43.76 E-value: 4.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 115 PGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPM-AHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPP 193
Cdd:pfam07174 34 PAVAHADPEPAPPPPSTATAPPAPPPPPPAPAAPAPPPPPAAPNApNAPPPPADPNAPPPPPADPNAPPPPAVDPNAPEP 113
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
162-235 |
5.06e-04 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 40.83 E-value: 5.06e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 257900508 162 PPPPGTPMAHPP--PPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAP 235
Cdd:pfam12526 31 PPESAHPDPPPPvgDPRPPVVDTPPPVSAVWVLPPPSEPAAPEPDLVPPVTGPAGPPSPLAPPAPAQKPPLPPPRP 106
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
113-242 |
5.56e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 44.03 E-value: 5.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 113 PPPGAPMaqPPTPGVLMVHPSAPGApMAHPPPPGTPMSHP-PPPGTPMAhpPPPGTPMAHPPPPGTpmvhPPPPGTPMAH 191
Cdd:TIGR01628 385 LPMGSPM--GGAMGQPPYYGQGPQQ-QFNGQPLGWPRMSMmPTPMGPGG--PLRPNGLAPMNAVRA----PSRNAQNAAQ 455
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 257900508 192 PPPpgtPMAHPPPPGTpMAHPPPPGTPmAHPPPPGTPMAQPPAPGVLMAQP 242
Cdd:TIGR01628 456 KPP---MQPVMYPPNY-QSLPLSQDLP-QPQSTASQGGQNKKLAQVLASAT 501
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
164-254 |
5.57e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 44.50 E-value: 5.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 164 PPGTPMAHPPPPGTPmvhPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPL 243
Cdd:PRK12270 38 PGSTAAPTAAAAAAA---AAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVE 114
|
90
....*....|.
gi 257900508 244 TPGVLMVQPAA 254
Cdd:PRK12270 115 DEVTPLRGAAA 125
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
225-366 |
6.05e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 44.09 E-value: 6.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 225 PGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLmihppGARAPMTQPPAS 304
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLL-----AARQQLQRAQGA 435
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 305 GAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPP 366
Cdd:PRK07994 436 TKAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATP 497
|
|
| PTZ00395 |
PTZ00395 |
Sec24-related protein; Provisional |
111-227 |
6.13e-04 |
|
Sec24-related protein; Provisional
Pssm-ID: 185594 [Multi-domain] Cd Length: 1560 Bit Score: 44.30 E-value: 6.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 111 HPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPP----PPGTPMAHPPPPGTPMVHpPPPG 186
Cdd:PTZ00395 416 NPGNSNPGYNNAPNSNTPYNNPPNSNTPYSNPPNSNPPYSNLPYSNTPYSNAPlsnaPPSSAKDHHSAYHAAYQH-RAAN 494
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 257900508 187 TPMAHPPPPGTPMAHP-----------PPPGTPMAHPPPPGTPMAHPPPPGT 227
Cdd:PTZ00395 495 QPAANLPTANQPAANNfhgaagnsvgnPFASRPFGSAPYGGNAATTADPNGI 546
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
133-303 |
6.58e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 44.05 E-value: 6.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 133 SAPGAPMAHPPPPGTPmsHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPP-------PGTPMAHPPPP 205
Cdd:PRK14086 85 AITVDPSAGEPAPPPP--HARRTSEPELPRPGRRPYEGYGGPRADDRPPGLPRQDQLPTARPaypayqqRPEPGAWPRAA 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 206 G------TPMAHPPP-PGTPMAHPPPPGTPMAQPPAPG-----VLMAQPLTPGVLMVQPAAPGAPMVQPPPAAmmtqpqp 273
Cdd:PRK14086 163 DdygwqqQRLGFPPRaPYASPASYAPEQERDREPYDAGrpeydQRRRDYDHPRPDWDRPRRDRTDRPEPPPGA------- 235
|
170 180 190
....*....|....*....|....*....|
gi 257900508 274 SGAPMAKPPGPGVLMIHPPGARAPMTQPPA 303
Cdd:PRK14086 236 GHVHRGGPGPPERDDAPVVPIRPSAPGPLA 265
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
132-203 |
6.71e-04 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 43.38 E-value: 6.71e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 257900508 132 PSAPGAPMAHPPPPGTPMShPPPPGTPMAHPPPPGTPM-AHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPP 203
Cdd:pfam07174 42 EPAPPPPSTATAPPAPPPP-PPAPAAPAPPPPPAAPNApNAPPPPADPNAPPPPPADPNAPPPPAVDPNAPEP 113
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
133-233 |
6.98e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 44.00 E-value: 6.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 133 SAPGAPMAHPPPPGT-PMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMvhPPPPGTPMAHPPPPGTPMAHPPPPGTPMAH 211
Cdd:PRK14971 370 SGGRGPKQHIKPVFTqPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSA--TQPAGTPPTVSVDPPAAVPVNPPSTAPQAV 447
|
90 100
....*....|....*....|..
gi 257900508 212 PPPPGTPMAHPPPPGTPMAQPP 233
Cdd:PRK14971 448 RPAQFKEEKKIPVSKVSSLGPS 469
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
112-302 |
7.21e-04 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 43.76 E-value: 7.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 112 PPPPGAPMAQPPTP-GVLMVHPSAPGAPMAHPPPPGTPMSHPP-PPGTPMAHPPPPGTPMAHPPPPGTPMVHP----PPP 185
Cdd:PLN03209 328 VPPKESDAADGPKPvPTKPVTPEAPSPPIEEEPPQPKAVVPRPlSPYTAYEDLKPPTSPIPTPPSSSPASSKSvdavAKP 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 186 GTPMAHP---PPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQpltpgvlmVQPAAPGAPMVQP 262
Cdd:PLN03209 408 AEPDVVPspgSASNVPEVEPAQVEAKKTRPLSPYARYEDLKPPTSPSPTAPTGVSPSVS--------STSSVPAVPDTAP 479
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 257900508 263 PPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPP 302
Cdd:PLN03209 480 ATAATDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVG 519
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
433-602 |
8.07e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 43.71 E-value: 8.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 433 APPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPP 512
Cdd:PRK12323 390 AAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGP 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 513 LWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPATQVPA-----APPAGPQVPQPVLPAPLSAPLSAPQAVHCPSIIW 587
Cdd:PRK12323 470 RPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPApaqpdAAPAGWVAESIPDPATADPDDAFETLAPAPAAAP 549
|
170
....*....|....*
gi 257900508 588 QAPKGQPPVPHEIPT 602
Cdd:PRK12323 550 APRAAAATEPVVAPR 564
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
451-711 |
8.10e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 43.92 E-value: 8.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 451 IRQAPPVIRQAPAVirQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLA--TQPPLWQALPPPPPLRQAPQ 528
Cdd:PRK10263 340 VTQTPPVASVDVPP--AQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEplQQPVQPQQPYYAPAAEQPAQ 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 529 ARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQpvlpaplsAPLSAPQAVHCPSIIWQAPKGQPPvPHEIPTSMEFQE 608
Cdd:PRK10263 418 QPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQ--------QSTFAPQSTYQTEQTYQQPAAQEP-LYQQPQPVEQQP 488
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 609 VQQTQALAWQAQKA--PTHIWQPLPAQEAqRQAPPLVQLEQPFQGAPPSQKAVQIQLPPQQAQASGPQAEVPTL-PLQPS 685
Cdd:PRK10263 489 VVEPEPVVEETKPArpPLYYFEEVEEKRA-REREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVsPLASG 567
|
250 260
....*....|....*....|....*.
gi 257900508 686 WQAppAVLQAQPGPPVAAANFPLGSA 711
Cdd:PRK10263 568 VKK--ATLATGAAATVAAPVFSLANS 591
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
183-282 |
8.42e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 43.61 E-value: 8.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 183 PPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQP 262
Cdd:PRK14971 370 SGGRGPKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAPQAVRP 449
|
90 100
....*....|....*....|
gi 257900508 263 PPAAMMTQPQPSGAPMAKPP 282
Cdd:PRK14971 450 AQFKEEKKIPVSKVSSLGPS 469
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
25-255 |
8.56e-04 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 43.89 E-value: 8.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 25 RPTVLMRAP--PASSRAPPVPWDPPPIDLQASLAaWQAPQPAWEAPQGQLPAPV-----------VPMTQPPALGGPIVP 91
Cdd:PHA03379 536 VPTVALERPvcPAPPLIAMQGPGETSGIVRVRER-WRPAPWTPNPPRSPSQMSVrdrlarlraeaQPYQASVEVQPPQLT 614
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 92 APPLGGPMGKPPTPGVLMVHPPP----------PGAPMAQPPTPGVLMVHPSAPGAPMA-----HPPPPGTPMSHPPPPG 156
Cdd:PHA03379 615 QVSPQQPMEYPLEPEQQMFPGSPfsqvadvmraGGVPAMQPQYFDLPLQQPISQGAPLAplrasMGPVPPVPATQPQYFD 694
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 157 TPMAHPPPPGTPMAH--PPPPGTPMVHPPPPGTPMAHPPPPGTP-MAHPPPPGTPMAHPPPPGTPMAHPPPpgtpmaQPP 233
Cdd:PHA03379 695 IPLTEPINQGASAAHflPQQPMEGPLVPERWMFQGATLSQSVRPgVAQSQYFDLPLTQPINHGAPAAHFLH------QPP 768
|
250 260
....*....|....*....|..
gi 257900508 234 APGvlmaqPLTPGVLMVQPAAP 255
Cdd:PHA03379 769 MEG-----PWVPEQWMFQGAPP 785
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
529-703 |
9.34e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 43.32 E-value: 9.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 529 ARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQvpqpvlpaplsaplsapqavhcpsiiwQAPKGQPPVPHEIPTSmefQE 608
Cdd:PRK07994 373 QSAAPAASAQATAAPTAAVAPPQAPAVPPPPA---------------------------SAPQQAPAVPLPETTS---QL 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 609 VQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQIQlPPQQAQASGPQAEVPTLPLQPSwqA 688
Cdd:PRK07994 423 LAARQQLQRAQGATKAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKK-EAYRWKATNPVEVKKEPVATPK--A 499
|
170
....*....|....*
gi 257900508 689 PPAVLQAQPGPPVAA 703
Cdd:PRK07994 500 LKKALEHEKTPELAA 514
|
|
| FAP |
pfam07174 |
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment ... |
165-235 |
9.47e-04 |
|
Fibronectin-attachment protein (FAP); This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.
Pssm-ID: 429334 Cd Length: 301 Bit Score: 42.61 E-value: 9.47e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 165 PGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPM-AHPPPPGTPMAHPPPPGTPMAQPPAP 235
Cdd:pfam07174 34 PAVAHADPEPAPPPPSTATAPPAPPPPPPAPAAPAPPPPPAAPNApNAPPPPADPNAPPPPPADPNAPPPPA 105
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
446-581 |
9.69e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 43.49 E-value: 9.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 446 QAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPaPQVLATQPPLWQALPPPPPLRQ 525
Cdd:pfam09770 206 QAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHP-VTILQRPQSPQPDPAQPSIQPQ 284
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 257900508 526 APQARLPAPQVQAAP----QVPTAPPATQVPA----APPAGPQVPQPVLPAPLSAPLSAPQAVH 581
Cdd:pfam09770 285 AQQFHQQPPPVPVQPtqilQNPNRLSAARVGYpqnpQPGVQPAPAHQAHRQQGSFGRQAPIITH 348
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
460-824 |
1.00e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.44 E-value: 1.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 460 QAPAVIRQAPPVIRQAPPvirQAPPVIRQAPPLIRQAPPPIRPAPqvlATQPPLWQALPPPPPLRQAPQARLPAPQVQAA 539
Cdd:PRK07764 396 AAAPSAAAAAPAAAPAPA---AAAPAAAAAPAPAAAPQPAPAPAP---APAPPSPAGNAPAGGAPSPPPAAAPSAQPAPA 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 540 PQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAP-------------QAVHCPSIIWQAPKGQPPVPHEI------ 600
Cdd:PRK07764 470 PAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADdaatlrerwpeilAAVPKRSRKTWAILLPEATVLGVrgdtlv 549
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 601 -----PTSMEF-----------QEVQQTQALAWQ--AQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVqiQ 662
Cdd:PRK07764 550 lgfstGGLARRfaspgnaevlvTALAEELGGDWQveAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAA--P 627
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 663 LPPQQAQASGPQAEVPTLPLQPS------WQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRASSIDRRGSSKERR 736
Cdd:PRK07764 628 APAGAAAAPAEASAAPAPGVAAPehhpkhVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAA 707
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 737 TSSKERR-APSKDRMIFAATFCAPKAVSAARAHLPAAWKNLPATPETFAPSSSVFPATSQFQPASLNAFKGPSAASETPK 815
Cdd:PRK07764 708 TPPAGQAdDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAE 787
|
....*....
gi 257900508 816 SLPYALQDP 824
Cdd:PRK07764 788 DDAPSMDDE 796
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
158-281 |
1.06e-03 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 43.26 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 158 PMAHPPPPGTPMahPPPPGTPMVHPPPPGTPMahpppPGTPMAHPPPPgtPMahpPPPGTPMAHPPPPG-TPMAQPPAPG 236
Cdd:TIGR01628 380 PRMRQLPMGSPM--GGAMGQPPYYGQGPQQQF-----NGQPLGWPRMS--MM---PTPMGPGGPLRPNGlAPMNAVRAPS 447
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 257900508 237 vLMAQPLTPgvlmvqpaapgapmvQPPPAAMMTQPQPSGAPMAKP 281
Cdd:TIGR01628 448 -RNAQNAAQ---------------KPPMQPVMYPPNYQSLPLSQD 476
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
192-288 |
1.13e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 43.26 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 192 PPPPGTPMAHPPPPGTPMAHPP-PPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPP--AAMM 268
Cdd:PRK14950 365 APQPAKPTAAAPSPVRPTPAPStRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAIPVdeKPKY 444
|
90 100
....*....|....*....|
gi 257900508 269 TQPQPSGAPMAKPPGPGVLM 288
Cdd:PRK14950 445 TPPAPPKEEEKALIADGDVL 464
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
431-557 |
1.13e-03 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 42.63 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 431 RQAPPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQ 510
Cdd:PTZ00436 218 KAAAPAKAAAAPAKAAAPPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAA 297
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 257900508 511 PPLWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPATqvPAAPPA 557
Cdd:PTZ00436 298 APAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAATPPAK--AAAPPA 342
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
11-305 |
1.17e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.24 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 11 SSPPAEAPKPPVYSRPTVL-----------MRAPPASSRAPPVPWDPppidlqaslaawqAPQPAWEAPQGQLPAPVVPM 79
Cdd:PHA03307 25 PATPGDAADDLLSGSQGQLvsdsaelaavtVVAGAAACDRFEPPTGP-------------PPGPGTEAPANESRSTPTWS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 80 TQPPALGGPIVPAPPLGGPMGKPPTPGvlmvHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPGTPm 159
Cdd:PHA03307 92 LSTLAPASPAREGSPTPPGPSSPDPPP----PTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDA- 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 160 AHPPPPGTPMAHPPPPGTPmvhPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLM 239
Cdd:PHA03307 167 ASSRQAALPLSSPEETARA---PSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSE 243
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 257900508 240 AQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGvlmihPPGARAPMTQPPASG 305
Cdd:PHA03307 244 SSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSS-----SPRERSPSPSPSSPG 304
|
|
| DUF3729 |
pfam12526 |
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ... |
132-207 |
1.40e-03 |
|
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.
Pssm-ID: 372164 [Multi-domain] Cd Length: 115 Bit Score: 39.68 E-value: 1.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 132 PSAPGAPMAHPPPPGTPMSHP----PPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAhPPPPGTPMAHPPPPGT 207
Cdd:pfam12526 29 FSPPESAHPDPPPPVGDPRPPvvdtPPPVSAVWVLPPPSEPAAPEPDLVPPVTGPAGPPSPLA-PPAPAQKPPLPPPRPQ 107
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
142-218 |
1.43e-03 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 42.13 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 142 PPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPgtpmvhPPPPGTPmAHPPPPGTPMAHPPPPGTPMA----HPPPPGT 217
Cdd:PLN02983 144 PPPPAPVVMMQPPPPHAMPPASPPAAQPAPSAPA------SSPPPTP-ASPPPAKAPKSSHPPLKSPMAgtfyRSPAPGE 216
|
.
gi 257900508 218 P 218
Cdd:PLN02983 217 P 217
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
81-235 |
1.44e-03 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 42.45 E-value: 1.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 81 QPPALGGPIVP----APPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPMSHPPPPG 156
Cdd:NF040712 169 DPGAHGGTVTAlddeARWLIDPDFGRPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRR 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 157 TPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPP--PPGTPMAHPPPPGTPMAQPPA 234
Cdd:NF040712 249 RAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPAPGAAETPEAAEPPAPAPAAPAAPaaPEAEEPARPEPPPAPKPKRRR 328
|
.
gi 257900508 235 P 235
Cdd:NF040712 329 R 329
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
433-570 |
1.52e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.78 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 433 APPLIRQAPPVIRQAPPVIRQAPPvirqapavirqAPPVirqappvirQAPPVIRQAPPLIRQAPPPiRPAPQVLATQPP 512
Cdd:PRK14951 392 APVAQAAAAPAPAAAPAAAASAPA-----------APPA---------AAPPAPVAAPAAAAPAAAP-AAAPAAVALAPA 450
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 257900508 513 LWQAlppppplrqapqarlPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPL 570
Cdd:PRK14951 451 PPAQ---------------AAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEE 493
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
183-386 |
1.67e-03 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 42.72 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 183 PPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPG----------------TPMAH----PPPPGTPMAQPPAPGVLMAQP 242
Cdd:pfam09770 107 PAARAAQSSAQPPASSLPQYQYASQQSQQPSKPVrtgyekykepepipdlQVDASlwgvAPKKAAAPAPAPQPAAQPASL 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 243 LTPGVLMV-------QPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAAPP 315
Cdd:pfam09770 187 PAPSRKMMsleeveaAMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPVTIL 266
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 257900508 316 AQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPGWQATSPGWQATQQGWQATP 386
Cdd:pfam09770 267 QRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVGYPQNPQPGVQPAPAHQAHRQQG 337
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
501-635 |
1.67e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.78 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 501 RPAPQVLATQPPLWQALPPPPPlrqAPQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAV 580
Cdd:PRK14951 365 KPAAAAEAAAPAEKKTPARPEA---AAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAA 441
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 257900508 581 HCPSIIWQAPKGQP-PVPHEIPTSMEFQEVQQTQALAWQAQKAPTHI------------WQPLPAQEA 635
Cdd:PRK14951 442 PAAVALAPAPPAQAaPETVAIPVRVAPEPAVASAAPAPAAAPAAARLtpteegdvwhatVQQLAAAEA 509
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
430-597 |
1.73e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 42.53 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 430 VRQAPPLIRQAPPVIRQAPPVIRQAPPVirqAPAVIRQAPPVIRQAPPVIRQAPPViRQAPPLIRQAppPIRPAPQVLAT 509
Cdd:PRK07003 376 VAGAVPAPGARAAAAVGASAVPAVTAVT---GAAGAALAPKAAAAAAATRAEAPPA-APAPPATADR--GDDAADGDAPV 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 510 QPPLWQALPPPPPLRQAPQARLPAPQVQAAPqVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPSIIWQ- 588
Cdd:PRK07003 450 PAKANARASADSRCDERDAQPPADSGSASAP-ASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPp 528
|
....*....
gi 257900508 589 APKGQPPVP 597
Cdd:PRK07003 529 APEARPPTP 537
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
132-212 |
1.82e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 42.57 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 132 PSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPmvhPPPPGTPMAHPPPPGTPMAHPPPPGTPMAH 211
Cdd:PRK12270 42 AAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAA---AAAAAAAPAAPPAAAAAAAPAAAAVEDEVT 118
|
.
gi 257900508 212 P 212
Cdd:PRK12270 119 P 119
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
507-724 |
1.84e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.56 E-value: 1.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 507 LATQPPLWQALPPPPPLRQAPQARlpAPQVQAAPQVPTAPPATqvPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPSII 586
Cdd:PRK12323 361 LAFRPGQSGGGAGPATAAAAPVAQ--PAPAAAAPAAAAPAPAA--PPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAA 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 587 WQAPKGQPPVPHEIPTSMEFQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAvqiqlPPQ 666
Cdd:PRK12323 437 RQASARGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFAS-----PAP 511
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 257900508 667 QAQASGPQAEVPTLPLQPSWQAPPAVLQAQPGPPVAAANFPLGSAKSLMTPSGECRAS 724
Cdd:PRK12323 512 AQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRAS 569
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
156-372 |
1.96e-03 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 42.45 E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 156 GTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPP----PGTPMAHPP------PP 225
Cdd:pfam03154 169 TQPPVLQAQSGAASPPSPPPPGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPhtliQQTPTLHPQrlpsphPP 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 226 GTPMAQPPAPGVLMAQPLTPGVL------MVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARApmT 299
Cdd:pfam03154 249 LQPMTQPPPPSQVSPQPLPQPSLhgqmppMPHSLQTGPSHMQHPVPPQPFPLTPQSSQSQVPPGPSPAAPGQSQQRI--H 326
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 257900508 300 QPPASGAPMAQPAAPPAQPMAPPAQPMASWAPQAQPLILQIQSQVIRAPPQVPQ-GPQAPPAQLATPPGWQATS 372
Cdd:pfam03154 327 TPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQSHKHPPHLSGpSPFQMNSNLPPPPALKPLS 400
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
152-228 |
2.01e-03 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 41.75 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 152 PPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPgtpmahPPPPGTPmAHPPPPGTPMAHPPPPGTPMA----HPPPPGT 227
Cdd:PLN02983 144 PPPPAPVVMMQPPPPHAMPPASPPAAQPAPSAPA------SSPPPTP-ASPPPAKAPKSSHPPLKSPMAgtfyRSPAPGE 216
|
.
gi 257900508 228 P 228
Cdd:PLN02983 217 P 217
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
433-577 |
2.06e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 42.16 E-value: 2.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 433 APPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAppliRQAPPPIRPAPQVLATQPP 512
Cdd:PRK07994 376 APAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRA----QGATKAKKSEPAAASRARP 451
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 257900508 513 LWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPA---TQVPAAPPAGPQVPQPVLPAPLSAPLSAP 577
Cdd:PRK07994 452 VNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVevkKEPVATPKALKKALEHEKTPELAAKLAAE 519
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
114-213 |
2.08e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 42.46 E-value: 2.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 114 PPGAPMAQPPTPGVLmvHPSAPGAPMAHPPPPGTP--MSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAH 191
Cdd:PRK14971 370 SGGRGPKQHIKPVFT--QPAAAPQPSAAAAASPSPsqSSAAAQPSAPQSATQPAGTPPTVSVDPPAAVPVNPPSTAPQAV 447
|
90 100
....*....|....*....|..
gi 257900508 192 PPPPGTPMAHPPPPGTPMAHPP 213
Cdd:PRK14971 448 RPAQFKEEKKIPVSKVSSLGPS 469
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
347-707 |
2.25e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 42.28 E-value: 2.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 347 APPQVPQGPQAPPAQLATPPGWQATSPGWQATQ--QGWQATPLTWQTTQVTWQAPAVTWQVPPPMRQGPPPIRPGPPPIR 424
Cdd:PRK07764 394 PAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAaaPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAA 473
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 425 PGPPPVRQAPPLIRQAPPVIRQAPPVirQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQ--------- 495
Cdd:PRK07764 474 PEPTAAPAPAPPAAPAPAAAPAAPAA--PAAPAGADDAATLRERWPEILAAVPKRSRKTWAILLPEATVLGvrgdtlvlg 551
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 496 -APPPIRPA------PQVLATQPPLWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPAtqvPAAPPAGPQVPQPVLPA 568
Cdd:PRK07764 552 fSTGGLARRfaspgnAEVLVTALAEELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEE---AARPAAPAAPAAPAAPA 628
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 569 PLSAPlSAPQAVHCPSIIWQAPKGQPPVPHEIPTSMEfqEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQP 648
Cdd:PRK07764 629 PAGAA-AAPAEASAAPAPGVAAPEHHPKHVAVPDASD--GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP 705
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 257900508 649 FQGAPPSQKAVQIQLPPQQAQASGPQAEVPTL--PLQPSWQAPPAVLQAQPGPPVAAANFP 707
Cdd:PRK07764 706 AATPPAGQADDPAAQPPQAAQGASAPSPAADDpvPLPPEPDDPPDPAGAPAQPPPPPAPAP 766
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
132-206 |
2.27e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 42.57 E-value: 2.27e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 257900508 132 PSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPG 206
Cdd:PRK12270 40 STAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVE 114
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
156-235 |
2.48e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 42.26 E-value: 2.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 156 GTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPmAHPPPPGTPMAHPPPPGTPMAQPPAP 235
Cdd:PRK14948 515 GSASNTAKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAP-AQIPADSSPPPPIPEEPTPSPTKDSS 593
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
152-217 |
2.71e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 42.04 E-value: 2.71e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 257900508 152 PPPPGTPMAHPPPPGTPmahpPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGT 217
Cdd:PRK14965 384 PPSAAWGAPTPAAPAAP----PPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAAS 445
|
|
| PRK12438 |
PRK12438 |
hypothetical protein; Provisional |
175-234 |
2.79e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 171499 [Multi-domain] Cd Length: 991 Bit Score: 42.16 E-value: 2.79e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 175 PGTPMVHPPPPGTPmAHPPPPGTPMAHPPPPGtpmahpPPPGTPMAHPPPPGTPMAQPPA 234
Cdd:PRK12438 897 PGTGRVATAPGGDA-ASAPPPGAGPPAPPQAV------PPPRTTQPPAAPPRGPDVPPAA 949
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
98-178 |
2.81e-03 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 40.98 E-value: 2.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 98 PMGKPPTPGVLMVHPPPPGAPMAQPPtpgvlmvhPSAPGAPMAHPPPPGTPMShPPPPGTPMAHPPPPGTPMA----HPP 173
Cdd:PLN02983 142 PQPPPPAPVVMMQPPPPHAMPPASPP--------AAQPAPSAPASSPPPTPAS-PPPAKAPKSSHPPLKSPMAgtfyRSP 212
|
....*
gi 257900508 174 PPGTP 178
Cdd:PLN02983 213 APGEP 217
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
6-151 |
2.93e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.90 E-value: 2.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 6 KNLGDSSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPAL 85
Cdd:PRK07764 655 KHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPA 734
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 257900508 86 GGPIVPAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVlmVHPSAPGAPMAHPPPPGTPMSH 151
Cdd:PRK07764 735 ADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPP--SPPSEEEEMAEDDAPSMDDEDR 798
|
|
| Neisseria_TspB |
pfam05616 |
Neisseria meningitidis TspB protein; This family consists of several Neisseria meningitidis ... |
142-208 |
3.33e-03 |
|
Neisseria meningitidis TspB protein; This family consists of several Neisseria meningitidis TspB virulence factor proteins.
Pssm-ID: 283306 [Multi-domain] Cd Length: 517 Bit Score: 41.62 E-value: 3.33e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 257900508 142 PPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPP---PGT-PMVHPPPPGTPMAHPPPPGTPMAHPPPPGTP 208
Cdd:pfam05616 326 PRPDLTPASAEAPHAQPLPEVSPAENPANNPDPdenPGTrPNPEPDPDLNPDANPDTDGQPGTRPDSPAVP 396
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
249-704 |
3.59e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.51 E-value: 3.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 249 MVQPAAPGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGvlmihPPGARAPMTQPPASGAPMAQPAAPPAQPMAPpaqpmas 328
Cdd:PRK07764 362 MLLPSASDDERGLLARLERLERRLGVAGGAGAPAAAA-----PSAAAAAPAAAPAPAAAAPAAAAAPAPAAAP------- 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 329 wAPQAQPLILQIQSQVIRAPPQVPQGPQAPPAQLATPPGWQATSPgwQATQQGWQATPLTWQTTQVTWQAPAVTwqvppp 408
Cdd:PRK07764 430 -QPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAA--PEPTAAPAPAPPAAPAPAAAPAAPAAP------ 500
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 409 mrqgpppirpGPPPIRPGPPPVRQAPPLIRQAPPVIRQAPPVIRQAPPVIRQapavIRQAPPVIRQAPPVIRQA------ 482
Cdd:PRK07764 501 ----------AAPAGADDAATLRERWPEILAAVPKRSRKTWAILLPEATVLG----VRGDTLVLGFSTGGLARRfaspgn 566
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 483 PPVIRQApplIRQAPPPIRPAPQVLATQPPLWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVP 562
Cdd:PRK07764 567 AEVLVTA---LAEELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAP 643
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 563 QPVLPAPLSAPLSAPQAVHCPSIIWQAPKGQPPVPHEIPTSMEfQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPL 642
Cdd:PRK07764 644 APGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPA-PAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPP 722
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 643 VQLEQpfQGAPPSQKAVQIQLPPQ--------QAQASGPQAEVPTLPLQPSWQAPPAVLQAQPGPPVAAA 704
Cdd:PRK07764 723 QAAQG--ASAPSPAADDPVPLPPEpddppdpaGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDA 790
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
162-227 |
3.65e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 41.65 E-value: 3.65e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 257900508 162 PPPPGTPMAHPPPPGTPmvhpPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGT 227
Cdd:PRK14965 384 PPSAAWGAPTPAAPAAP----PPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAAS 445
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
52-205 |
3.97e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 41.39 E-value: 3.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 52 QASLAAWQAPQPAwEAPQGQLPAPVVPMTQPPALGGPIVPAPPlggpMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVH 131
Cdd:PRK07994 362 AAPLPEPEVPPQS-AAPAASAQATAAPTAAVAPPQAPAVPPPP----ASAPQQAPAVPLPETTSQLLAARQQLQRAQGAT 436
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 257900508 132 PSAPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPP 205
Cdd:PRK07994 437 KAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTP 510
|
|
| PRK12438 |
PRK12438 |
hypothetical protein; Provisional |
102-182 |
4.30e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 171499 [Multi-domain] Cd Length: 991 Bit Score: 41.39 E-value: 4.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 102 PPTPGVLMVHPPPPGAPMAQPPTPGVLMVhPSAPGAPMAHPPPPGTPMSHPPPPGtpmahpPPPGTPMAHPPPPGTPMVH 181
Cdd:PRK12438 874 RTEGGVRVGYAPTLAEALDQVFGPGTGRV-ATAPGGDAASAPPPGAGPPAPPQAV------PPPRTTQPPAAPPRGPDVP 946
|
.
gi 257900508 182 P 182
Cdd:PRK12438 947 P 947
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
174-291 |
5.06e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.22 E-value: 5.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 174 PPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPgtpmAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPA 253
Cdd:PRK10263 743 PLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQP----VAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQ 818
|
90 100 110
....*....|....*....|....*....|....*...
gi 257900508 254 APGAPMVQPPPAAmmtQPQPSGAPMakppgPGVLMIHP 291
Cdd:PRK10263 819 QPQQPVAPQPQYQ---QPQQPVAPQ-----PQDTLLHP 848
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
91-224 |
5.11e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.22 E-value: 5.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 91 PAPPLGGPMGKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGApmahPPPPGTPMSHPPPPGTPMAHPPPPGTPMA 170
Cdd:PRK10263 740 PHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVA----PQPQYQQPQQPVAPQPQYQQPQQPVAPQP 815
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 257900508 171 HPPPPGTPMVHPPPPGTPMAHPPP-PGTPMAHP----PPPGTPMAHP--PPPGTPMAHPPP 224
Cdd:PRK10263 816 QYQQPQQPVAPQPQYQQPQQPVAPqPQDTLLHPllmrNGDSRPLHKPttPLPSLDLLTPPP 876
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
440-583 |
5.20e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 41.18 E-value: 5.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 440 APPVIRQAPPVIRQAPPVIRQAPAVirQAPPVIRQAPPVIRQAPPVIrQAPplIRQAPPPIRPAPQVLATQPPLWQALPP 519
Cdd:PRK10811 876 AAAVEPVVSAPVVEAVAEVVEEPVV--VAEPQPEEVVVVETTHPEVI-AAP--VTEQPQVITESDVAVAQEVAEHAEPVV 950
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 257900508 520 PPPLRQApqarlPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCP 583
Cdd:PRK10811 951 EPQDETA-----DIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEA 1009
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
172-236 |
5.50e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 40.88 E-value: 5.50e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 257900508 172 PPPPGTPMVHPPPPGTPmahpPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPG 236
Cdd:PRK14965 384 PPSAAWGAPTPAAPAAP----PPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAA 444
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
454-559 |
5.63e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 40.72 E-value: 5.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 454 APPVIRQAPAVIRQAPPVirqAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPPLWQALPPPPPLRQAPQArlPA 533
Cdd:PRK06995 52 APPAAAAPAAAQPPPAAA---PAAVSRPAAPAAEPAPWLVEHAKRLTAQREQLVARAAAPAAPEAQAPAAPAERAA--AE 126
|
90 100
....*....|....*....|....*.
gi 257900508 534 PQVQAAPQVPTAPPATQVPAAPPAGP 559
Cdd:PRK06995 127 NAARRLARAAAAAPRPRVPADAAAAV 152
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
158-386 |
5.71e-03 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 41.19 E-value: 5.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 158 PMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGV 237
Cdd:PHA03377 553 PKVSPSDRGPPKASPPVMAPPSTGPRVMATPSTGPRDMAPPSTGPRQQAKCKDGPPASGPHEKQPPSSAPRDMAPSVVRM 632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 238 LMAQPLTPGVLMVQPAA--------PGAPMVQPPPAAMMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASGAPMA 309
Cdd:PHA03377 633 FLRERLLEQSTGPKPKSfwemragrDGSGIQQEPSSRRQPATQSTPPRPSWLPSVFVLPSVDAGRAQPSEESHLSSMSPT 712
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 310 QPAAPPAQPMAPPaqpmaswaPQAQpliLQIQSQVIRAPPQVPQGP----QAPPAQLATPPGWQATSPGwQATQQGWQAT 385
Cdd:PHA03377 713 QPISHEEQPRYED--------PDDP---LDLSLHPDQAPPPSHQAPysghEEPQAQQAPYPGYWEPRPP-QAPYLGYQEP 780
|
.
gi 257900508 386 P 386
Cdd:PHA03377 781 Q 781
|
|
| KLF2_N |
cd21583 |
N-terminal domain of Kruppel-like factor 2; Kruppel-like Factor 2 (KLF2, also known as ... |
140-228 |
5.80e-03 |
|
N-terminal domain of Kruppel-like factor 2; Kruppel-like Factor 2 (KLF2, also known as Krueppel-like factor 2 or lung Kruppel-like Factor/LKLF) is a protein that, in humans, is encoded by the KLF2 gene on chromosome 19. It has been implicated in a variety of biochemical processes in the human body, including lung development, embryonic erythropoiesis, epithelial integrity, T-cell viability, and adipogenesis. KLF proteins KLF1, KLF2, KLF4, KLF5, KLF6, and KLF7 are transcriptional activators. KLF2 belongs to a family of proteins called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specificity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domain of KLF2, which is related to the N-terminal domains of KLF1 and KLF4.
Pssm-ID: 409229 [Multi-domain] Cd Length: 299 Bit Score: 40.40 E-value: 5.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 140 AHPPPPGTPMSHPPPPGTPMAHPPPPgtPMAHPPPPGTPMVHPPPPgtpmaHPPPPGTPMAHPPPPGTPMAHPPPPGTPM 219
Cdd:cd21583 195 ANSPQAAGSMTPPLSPDDLMASECQQ--QMMCSPSFPQPHHPHYPP-----PPQPPLQYQSPHQFGLFEDGLPLQPSAQR 267
|
....*....
gi 257900508 220 AHPPPPGTP 228
Cdd:cd21583 268 VLLTPPSSP 276
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
469-639 |
5.99e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 40.85 E-value: 5.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 469 PPVIRQAPPVIRQAPPvIRQAPPLIRQAPPPIRPAPQVLATQPPLWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPA 548
Cdd:PRK14951 366 PAAAAEAAAPAEKKTP-ARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAA 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 549 TQVPAAPPAGPQvPQPVLPAPLSAPLSAPQAVHCPsiiwqaPKGQPPVPHEIPTSME---FQEVQQ----------TQAL 615
Cdd:PRK14951 445 VALAPAPPAQAA-PETVAIPVRVAPEPAVASAAPA------PAAAPAAARLTPTEEGdvwHATVQQlaaaeaitalAREL 517
|
170 180
....*....|....*....|....*.
gi 257900508 616 AWQAQ--KAPTHIWQPLPAQEAQRQA 639
Cdd:PRK14951 518 ALQSElvARDGDQWLLRVERESLNQP 543
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
100-303 |
6.00e-03 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 40.83 E-value: 6.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 100 GKPPTPGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPmAHPPPPGTPMShPPPPGTPM--AHPPPPGTPMAHPPPPGT 177
Cdd:PTZ00449 547 GKPGETKEGEVGKKPGPAKEHKPSKIPTLSKKPEFPKDP-KHPKDPEEPKK-PKRPRSAQrpTRPKSPKLPELLDIPKSP 624
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 178 PmvHPPPPGTPMAhPPPPGTPMAHPPPPGTPMahPPPPGTPMAhPPPPGTP---------------MAQPPAPGVLMAQP 242
Cdd:PTZ00449 625 K--RPESPKSPKR-PPPPQRPSSPERPEGPKI--IKSPKPPKS-PKPPFDPkfkekfyddyldaaaKSKETKTTVVLDES 698
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 257900508 243 LTPGVLMVQPAAPGAPMVQPP--PAAMMTQPQ----PSGAPMAKPPGPGVLMIHPPGARAPMTQPPA 303
Cdd:PTZ00449 699 FESILKETLPETPGTPFTTPRplPPKLPRDEEfpfePIGDPDAEQPDDIEFFTPPEEERTFFHETPA 765
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
480-705 |
6.14e-03 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 40.96 E-value: 6.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 480 RQAPPVIRQappLIRQAPPPIRPAPQVLATQPPLWQALPPPPPLRQAPQARLPA------PQVQAAPQVPTAPPATQVPA 553
Cdd:PRK14086 65 RLAPIISET---LSRELGRPIRIAITVDPSAGEPAPPPPHARRTSEPELPRPGRrpyegyGGPRADDRPPGLPRQDQLPT 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 554 APPAGPQVPQPVLPAPL-SAPLSAPqavhcpsiiWQAPKGQPPVPHEIPTSMEFQEVQQTqalawqaqkapthiWQPLPA 632
Cdd:PRK14086 142 ARPAYPAYQQRPEPGAWpRAADDYG---------WQQQRLGFPPRAPYASPASYAPEQER--------------DREPYD 198
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 257900508 633 QEAQRQAPPLVQLEQPFQGA-PPSQKAVQIQLPPQQA----QASGPQAEVPTLPLQPSWQAPPAVLQAQPGPPVAAAN 705
Cdd:PRK14086 199 AGRPEYDQRRRDYDHPRPDWdRPRRDRTDRPEPPPGAghvhRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPGE 276
|
|
| Drf_FH1 |
pfam06346 |
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs) ... |
152-305 |
6.21e-03 |
|
Formin Homology Region 1; This region is found in some of the Diaphanous related formins (Drfs). It consists of low complexity repeats of around 12 residues.
Pssm-ID: 461881 [Multi-domain] Cd Length: 157 Bit Score: 38.70 E-value: 6.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 152 PPPPGTPMAHPPPPGTPMAHPPPPGtpmvhPPPPGTPMAHPPPPGTPMAHPPPPGTP--MAHPPPPGTPMAHPPPPGTPM 229
Cdd:pfam06346 1 PPPPPLPGDSSTIPLPPGACIPTPP-----PLPGGGGPPPPPPLPGSAAIPPPPPLPggTSIPPPPPLPGAASIPPPPPL 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 257900508 230 AQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMTQPqpsgAPMAKPPGPGVLMIHPPGARAPMTQPPASG 305
Cdd:pfam06346 76 PGSTGIPPPPPLPGGAGIPPPPPPLPGGAGVPPPPPPLPGGP----GIPPPPPFPGGPGIPPPPPGMGMPPPPPFG 147
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
136-215 |
6.21e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 40.72 E-value: 6.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 136 GAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPmAHPPPPGTPMAHPPPPGTPMAHPPPP 215
Cdd:PRK14948 515 GSASNTAKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAP-AQIPADSSPPPPIPEEPTPSPTKDSS 593
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
9-380 |
6.52e-03 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 40.76 E-value: 6.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 9 GDSSPPAEAPKPPVYSRPTVLMRAPPASSRAPPVPWDPPPIDLQASLAAWQAPQPAWEAPQGQLPAPVVPMTQPPALGGP 88
Cdd:pfam09606 92 QGTRPQMMGPMGPGPGGPMGQQMGGPGTASNLLASLGRPQMPMGGAGFPSQMSRVGRMQPGGQAGGMMQPSSGQPGSGTP 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 89 IVPAPPLGgpmgkpptpgvlmvhpppPGAPMAQPPTPGvlmvhpsaPGAPMAHPPPPGTPMSHPPPPGTPMAHPPPPGTP 168
Cdd:pfam09606 172 NQMGPNGG------------------PGQGQAGGMNGG--------QQGPMGGQMPPQMGVPGMPGPADAGAQMGQQAQA 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 169 MAHPPPPGtpmVHPPPPGTPMAHPPPPGTP----MAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLT 244
Cdd:pfam09606 226 NGGMNPQQ---MGGAPNQVAMQQQQPQQQGqqsqLGMGINQMQQMPQGVGGGAGQGGPGQPMGPPGQQPGAMPNVMSIGD 302
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 245 PGVLMVQPAAP--GAPMVQPPPAA--MMTQPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPASGAPMAQPAAPPAQPMA 320
Cdd:pfam09606 303 QNNYQQQQTRQqqQQQGGNHPAAHqqQMNQSVGQGGQVVALGGLNHLETWNPGNFGGLGANPMQRGQPGMMSSPSPVPGQ 382
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 321 PPAQpmaswapQAQPLILQIQSQVIRAPPQVP--QGPQAPPAQLATPPGWQAtSPGWQATQQ 380
Cdd:pfam09606 383 QVRQ-------VTPNQFMRQSPQPSVPSPQGPgsQPPQSHPGGMIPSPALIP-SPSPQMSQQ 436
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
534-696 |
6.57e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 40.53 E-value: 6.57e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 534 PQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLSAPQAVHCPsiiwqapkgqPPVPHEIPTSmefQEVQQTQ 613
Cdd:PRK14971 375 PKQHIKPVFTQPAAAPQPSAAAAASPSPSQSSAAAQPSAPQSATQPAGTP----------PTVSVDPPAA---VPVNPPS 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 614 ALAWQAQkapthiwqplPAQEAQRQAPPLVQLEQPfqgAPPSQKAVQiqlpPQQAQASGPQAEVPTLP---------LQP 684
Cdd:PRK14971 442 TAPQAVR----------PAQFKEEKKIPVSKVSSL---GPSTLRPIQ----EKAEQATGNIKEAPTGTqkeifteedLQY 504
|
170
....*....|..
gi 257900508 685 SWQAPPAVLQAQ 696
Cdd:PRK14971 505 YWQEFAGTRPQE 516
|
|
| PTZ00436 |
PTZ00436 |
60S ribosomal protein L19-like protein; Provisional |
433-547 |
6.76e-03 |
|
60S ribosomal protein L19-like protein; Provisional
Pssm-ID: 185616 [Multi-domain] Cd Length: 357 Bit Score: 40.32 E-value: 6.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 433 APPLIRQAPPVIRQAPPVIRQAPPVIRQAPAVIRQAPPVIRQAPPVIRQAPPVIRQAPPLIRQAPPPIRPAPQVLATQPP 512
Cdd:PTZ00436 234 APPAKAAAAPAKAAAAPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAPPAKAAAAPAKAAAAPAKAAAAP 313
|
90 100 110
....*....|....*....|....*....|....*
gi 257900508 513 LWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPP 547
Cdd:PTZ00436 314 AKAAAPPAKAAAPPAKAATPPAKAAAPPAKAAAAP 348
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
594-697 |
6.86e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 40.84 E-value: 6.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 594 PPVPHEIPTSMEFQEVQQTQALAWQAQKAPTHIWQPLPAQEAQRQAPPLVQLEQPFQGAPPSQKAVQiqlpPQQAQASGP 673
Cdd:PRK10263 740 PHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQ----PQQPVAPQP 815
|
90 100
....*....|....*....|....*.
gi 257900508 674 QAEVPTLPL--QPSWQAPPAVLQAQP 697
Cdd:PRK10263 816 QYQQPQQPVapQPQYQQPQQPVAPQP 841
|
|
| DUF4813 |
pfam16072 |
Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. ... |
131-215 |
7.02e-03 |
|
Domain of unknown function (DUF4813); This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. Proteins in this family are typically between 345 and 672 amino acids in length.
Pssm-ID: 435117 [Multi-domain] Cd Length: 288 Bit Score: 40.13 E-value: 7.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 131 HPSAPGAPMAHPPPPGTPMSHPPPPGTPMahPPPPGTPMAH-PPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGTPM 209
Cdd:pfam16072 167 QPAAPAAPAYPVAPAAYPAQAPAAAPAPA--PGAPQTPLAPlNPVAAAPAAAAGAAAAPVVAAAAPAAAAPPPPAPAAPP 244
|
....*.
gi 257900508 210 AHPPPP 215
Cdd:pfam16072 245 ADAAPP 250
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
146-225 |
7.12e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 40.72 E-value: 7.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 146 GTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPmAHPPPPGTPMAHPPPPGTPMAHPPPP 225
Cdd:PRK14948 515 GSASNTAKTPPPPQKSPPPPAPTPPLPQPTATAPPPTPPPPPPTATQASSNAP-AQIPADSSPPPPIPEEPTPSPTKDSS 593
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
182-272 |
7.28e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 40.64 E-value: 7.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 182 PPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPgvlmaqpltpgvlmVQPAAPGAPMVQ 261
Cdd:PRK12270 40 STAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAA--------------AAPAAPPAAAAA 105
|
90
....*....|.
gi 257900508 262 PPPAAMMTQPQ 272
Cdd:PRK12270 106 AAPAAAAVEDE 116
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
25-185 |
7.72e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 40.62 E-value: 7.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 25 RPTVLMRAPPASSRAPPVPWDPPPidlQASLAAWQAPQPAWEAPQGQLPAPVvpmtQPPALGGPIVPAPPLGGPMGKPPT 104
Cdd:PRK07994 360 HPAAPLPEPEVPPQSAAPAASAQA---TAAPTAAVAPPQAPAVPPPPASAPQ----QAPAVPLPETTSQLLAARQQLQRA 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 105 PGVLMVHPPPPGAPMAQPPTPGVLMVHPSAPGAPMAHPPPPGTPmshPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPP 184
Cdd:PRK07994 433 QGATKAKKSEPAAASRARPVNSALERLASVRPAPSALEKAPAKK---EAYRWKATNPVEVKKEPVATPKALKKALEHEKT 509
|
.
gi 257900508 185 P 185
Cdd:PRK07994 510 P 510
|
|
| Gag_spuma |
pfam03276 |
Spumavirus gag protein; |
111-233 |
7.79e-03 |
|
Spumavirus gag protein;
Pssm-ID: 460872 [Multi-domain] Cd Length: 614 Bit Score: 40.50 E-value: 7.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 111 HPPPPGAPMAQPPT-PGVLMVHPSAPGAPMAHPPPPGTPMSHPP--PPGTPMAHPP------PPGTPMAHPP--PPGTPM 179
Cdd:pfam03276 184 GGIPPGASFSGLPSlPAIGGIHLPAIPGIHARAPPGNIARSLGDdiMPSLGDAGMPqprfafHPGNPFAEAEghPFAEAE 263
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 257900508 180 VHPPPP-------GTPMAHPPPPGTPMAHPPPPGTPmAHPPPPGTPMAHPPPPGTPMAQPP 233
Cdd:pfam03276 264 GERPRDiprapriDAPSAPAIPAIQPIAPPMIPPIG-APIPIPHGASIPGEHIRNPREEPI 323
|
|
| Gag_spuma |
pfam03276 |
Spumavirus gag protein; |
160-305 |
7.86e-03 |
|
Spumavirus gag protein;
Pssm-ID: 460872 [Multi-domain] Cd Length: 614 Bit Score: 40.50 E-value: 7.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 160 AHPPPPGTPMAHPPP-PGTPMVHPPPPGTPMAHPPPPGTPMAHPP--PPGTPMAHPPPPGTPMAHPPPPGTPMAQPPAPG 236
Cdd:pfam03276 183 QGGIPPGASFSGLPSlPAIGGIHLPAIPGIHARAPPGNIARSLGDdiMPSLGDAGMPQPRFAFHPGNPFAEAEGHPFAEA 262
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 257900508 237 V---LMAQPLTPGVLMVQPAAPGAPMVQPPPaammtQPQPSGAPMAKPPGPGVLMIHPpgaRAPMTQPPASG 305
Cdd:pfam03276 263 EgerPRDIPRAPRIDAPSAPAIPAIQPIAPP-----MIPPIGAPIPIPHGASIPGEHI---RNPREEPIRLG 326
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
193-284 |
7.86e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 40.53 E-value: 7.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 193 PPPGTPMAHPPPPGT-PMAHPPPPGTPMAHPPPPGTPM-AQPPAPGVLMAQPLTPGVLMVQPaapGAPMVQPPPAAMMTQ 270
Cdd:PRK14971 370 SGGRGPKQHIKPVFTqPAAAPQPSAAAAASPSPSQSSAaAQPSAPQSATQPAGTPPTVSVDP---PAAVPVNPPSTAPQA 446
|
90
....*....|....
gi 257900508 271 PQPSGAPMAKPPGP 284
Cdd:PRK14971 447 VRPAQFKEEKKIPV 460
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
32-309 |
7.89e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 40.60 E-value: 7.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 32 APPASSRAPPVPWDPPPIDLQASLAAWQAPQPAwEAPQGQLPAPVVPMTQPPALGGPIVPAPPLGGPMGKPPTPGVLMVH 111
Cdd:PRK07003 372 VPARVAGAVPAPGARAAAAVGASAVPAVTAVTG-AAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVP 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 112 PPPPgAPMAQPPTPGVLMVHPSAPGAPMAHPPP--PGTPMSHPPPPGTPMAHPPPPGTPMAHPPPPGTPMVHPPPPGTPM 189
Cdd:PRK07003 451 AKAN-ARASADSRCDERDAQPPADSGSASAPASdaPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPA 529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 190 AHPPPPGTPMAHPPPPGTPMAHP-----------------PPPGTPMAHPPPPGTPMAQPPAPGVLMAQPLTPGVLMVQP 252
Cdd:PRK07003 530 PEARPPTPAAAAPAARAGGAAAAldvlrnagmrvssdrgaRAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAP 609
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 253 AAPGAPmvqPPPAAMMTQPQP-------------SGAPMAKPPGPGVLMIHPPGARAPMTQPPASgapmA 309
Cdd:PRK07003 610 PNGAAR---AEQAAESRGAPPpwedippddyvplSADEGFGGPDDGFVPVFDSGPDDVRVAPKPA----D 672
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
142-207 |
7.94e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 40.50 E-value: 7.94e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 257900508 142 PPPPGTPMSHPPPPGTPmahpPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPPPGTPMAHPPPPGT 207
Cdd:PRK14965 384 PPSAAWGAPTPAAPAAP----PPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAAS 445
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
191-303 |
7.99e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 40.62 E-value: 7.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 191 HPPPPGTPMAHPPPPGTPMAHPPPPGTPMAH-PPPPGTPMAQPPAPGVLMAQPLTPGVLMVQPAAPGAPMVQPPPAAMMT 269
Cdd:PRK07994 360 HPAAPLPEPEVPPQSAAPAASAQATAAPTAAvAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAK 439
|
90 100 110
....*....|....*....|....*....|....
gi 257900508 270 QPQPSGAPMAKPPGPGVLMIHPPGARAPMTQPPA 303
Cdd:PRK07994 440 KSEPAAASRARPVNSALERLASVRPAPSALEKAP 473
|
|
| Neisseria_TspB |
pfam05616 |
Neisseria meningitidis TspB protein; This family consists of several Neisseria meningitidis ... |
162-228 |
8.77e-03 |
|
Neisseria meningitidis TspB protein; This family consists of several Neisseria meningitidis TspB virulence factor proteins.
Pssm-ID: 283306 [Multi-domain] Cd Length: 517 Bit Score: 40.08 E-value: 8.77e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 257900508 162 PPPPGTPMAHPPPPGTPMVHPPPPGTPMAHPPP---PGT-PMAHPPPPGTPMAHPPPPGTPMAHPPPPGTP 228
Cdd:pfam05616 326 PRPDLTPASAEAPHAQPLPEVSPAENPANNPDPdenPGTrPNPEPDPDLNPDANPDTDGQPGTRPDSPAVP 396
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
496-579 |
9.95e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 40.26 E-value: 9.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 496 APPPIRPAPQVLATQPPLWQALPPPPPLRQAPQARLPAPQVQAAPQVPTAPPATQVPAAPPAGPQVPQPVLPAPLSAPLS 575
Cdd:PRK12270 42 AAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEVTPLR 121
|
....
gi 257900508 576 APQA 579
Cdd:PRK12270 122 GAAA 125
|
|
| PLN02983 |
PLN02983 |
biotin carboxyl carrier protein of acetyl-CoA carboxylase |
118-198 |
9.98e-03 |
|
biotin carboxyl carrier protein of acetyl-CoA carboxylase
Pssm-ID: 215533 [Multi-domain] Cd Length: 274 Bit Score: 39.44 E-value: 9.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 257900508 118 PMAQPPTPgVLMVHPSAPGAPMAHPPPPGTPMSHPPPpgtpmahPPPPGTPmAHPPPPGTPMVHPPPPGTPMA----HPP 193
Cdd:PLN02983 142 PQPPPPAP-VVMMQPPPPHAMPPASPPAAQPAPSAPA-------SSPPPTP-ASPPPAKAPKSSHPPLKSPMAgtfyRSP 212
|
....*
gi 257900508 194 PPGTP 198
Cdd:PLN02983 213 APGEP 217
|
|
| |
