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Conserved domains on  [gi|256818791|ref|NP_060168|]
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transmembrane protein 164 isoform a [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TMEM164 super family cl20724
TMEM164 family; This family of proteins is found in eukaryotes. Proteins in this family are ...
 1-124 1.77e-76

TMEM164 family; This family of proteins is found in eukaryotes. Proteins in this family are typically between 214 and 330 amino acids in length. There are two conserved sequence motifs: LNPCH and DPF.


The actual alignment was detected with superfamily member pfam14808:

Pssm-ID: 464327  Cd Length: 250  Bit Score: 227.51  E-value: 1.77e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818791    1 MHMLNGALLALLFPVVNTRLLPFELEIYYIQHVMLYVVPIYLLWKGGAYTPEPLSSFRWALLSTGLMFFYHFSVLQILGL 80
Cdd:pfam14808 127 LHMLNGALLALLFPVVNTRLLPFEVETYWIQHVLILVVPIYLLRLGGVYTVEPLSDFSWSVLSTGLFLLYHFIFLQPLGL 206

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 256818791   81 VTEVNLNNMLCPAISDPFYGPWYRIWASGHQTLMTMTHGKLVIL 124
Cdd:pfam14808 207 LTQVNLNNMLCPAVSDPFYGPYYRIWAVGHQTLLIPLLGKLYTL 250
 
Name Accession Description Interval E-value
TMEM164 pfam14808
TMEM164 family; This family of proteins is found in eukaryotes. Proteins in this family are ...
 1-124 1.77e-76

TMEM164 family; This family of proteins is found in eukaryotes. Proteins in this family are typically between 214 and 330 amino acids in length. There are two conserved sequence motifs: LNPCH and DPF.


Pssm-ID: 464327  Cd Length: 250  Bit Score: 227.51  E-value: 1.77e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818791    1 MHMLNGALLALLFPVVNTRLLPFELEIYYIQHVMLYVVPIYLLWKGGAYTPEPLSSFRWALLSTGLMFFYHFSVLQILGL 80
Cdd:pfam14808 127 LHMLNGALLALLFPVVNTRLLPFEVETYWIQHVLILVVPIYLLRLGGVYTVEPLSDFSWSVLSTGLFLLYHFIFLQPLGL 206

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 256818791   81 VTEVNLNNMLCPAISDPFYGPWYRIWASGHQTLMTMTHGKLVIL 124
Cdd:pfam14808 207 LTQVNLNNMLCPAVSDPFYGPYYRIWAVGHQTLLIPLLGKLYTL 250
 
Name Accession Description Interval E-value
TMEM164 pfam14808
TMEM164 family; This family of proteins is found in eukaryotes. Proteins in this family are ...
 1-124 1.77e-76

TMEM164 family; This family of proteins is found in eukaryotes. Proteins in this family are typically between 214 and 330 amino acids in length. There are two conserved sequence motifs: LNPCH and DPF.


Pssm-ID: 464327  Cd Length: 250  Bit Score: 227.51  E-value: 1.77e-76
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256818791    1 MHMLNGALLALLFPVVNTRLLPFELEIYYIQHVMLYVVPIYLLWKGGAYTPEPLSSFRWALLSTGLMFFYHFSVLQILGL 80
Cdd:pfam14808 127 LHMLNGALLALLFPVVNTRLLPFEVETYWIQHVLILVVPIYLLRLGGVYTVEPLSDFSWSVLSTGLFLLYHFIFLQPLGL 206

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 256818791   81 VTEVNLNNMLCPAISDPFYGPWYRIWASGHQTLMTMTHGKLVIL 124
Cdd:pfam14808 207 LTQVNLNNMLCPAVSDPFYGPYYRIWAVGHQTLLIPLLGKLYTL 250
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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