|
Name |
Accession |
Description |
Interval |
E-value |
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
1-316 |
0e+00 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 624.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 1 MDKPWVEKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPHLLFSGPPGVGKTTAALCLARDLFGENWRENFLELNASDERGI 80
Cdd:PRK00440 3 MEEIWVEKYRPRTLDEIVGQEEIVERLKSYVKEKNMPHLLFAGPPGTGKTTAALALARELYGEDWRENFLELNASDERGI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 81 DVIRTKVKDFARTKPIGDVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFSPLK 160
Cdd:PRK00440 83 DVIRNKIKEFARTAPVGGAPFKIIFLDEADNLTSDAQQALRRTMEMYSQNTRFILSCNYSSKIIDPIQSRCAVFRFSPLK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 161 KEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEVIDDEIVYKVSSRARPEEVKKMMELALEGK 240
Cdd:PRK00440 163 KEAVAERLRYIAENEGIEITDDALEAIYYVSEGDMRKAINALQAAAATGKEVTEEAVYKITGTARPEEIREMIELALNGD 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256794537 241 FVEARDLLYKLMVEWGMSGEDILNQMFREINNLDIDERKKVELADAIGETDFRIVEGANERIQLSALLAKMALMGK 316
Cdd:PRK00440 243 FTEAREKLRDLMIDYGLSGEDIIKQIHREVWSLDIPEELKVELIDAIGEADFRITEGANERIQLEALLAKLALLGK 318
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
44-316 |
2.15e-174 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 504.37 E-value: 2.15e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 44 PPGVGKTTAALCLARDLFGENWRENFLELNASDERGIDVIRTKVKDFARTKPIGDVPFKIIFLDESDALTPDAQNALRRT 123
Cdd:PRK04132 574 PTVLHNTTAALALARELFGENWRHNFLELNASDERGINVIREKVKEFARTKPIGGASFKIIFLDEADALTQDAQQALRRT 653
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 124 MEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQ 203
Cdd:PRK04132 654 MEMFSSNVRFILSCNYSSKIIEPIQSRCAIFRFRPLRDEDIAKRLRYIAENEGLELTEEGLQAILYIAEGDMRRAINILQ 733
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 204 TAAALSEVIDDEIVYKVSSRARPEEVKKMMELALEGKFVEARDLLYKLMVEWGMSGEDILNQMFREINNLDIDERKKVEL 283
Cdd:PRK04132 734 AAAALDDKITDENVFLVASRARPEDIREMMLLALKGNFLKAREKLREILLKQGLSGEDVLVQMHREVFNLPIDEPKKVEL 813
|
250 260 270
....*....|....*....|....*....|...
gi 256794537 284 ADAIGETDFRIVEGANERIQLSALLAKMALMGK 316
Cdd:PRK04132 814 ADKIGEYNFRLVEGANEMIQLEALLAQFTLMGK 846
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
4-313 |
1.10e-113 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 331.69 E-value: 1.10e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 4 PWVEKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPHLLFSGPPGVGKTTAALCLARDLFGENWRENFLELNASDERGIDVI 83
Cdd:PLN03025 2 PWVEKYRPTKLDDIVGNEDAVSRLQVIARDGNMPNLILSGPPGTGKTTSILALAHELLGPNYKEAVLELNASDDRGIDVV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 84 RTKVKDFARTK---PIGDvpFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFSPLK 160
Cdd:PLN03025 82 RNKIKMFAQKKvtlPPGR--HKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRFSRLS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 161 KEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEVIDDEIVYKVSSRARPEEVKKMMELALEGK 240
Cdd:PLN03025 160 DQEILGRLMKVVEAEKVPYVPEGLEAIIFTADGDMRQALNNLQATHSGFGFVNQENVFKVCDQPHPLHVKNIVRNCLKGK 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256794537 241 FVEARDLLyKLMVEWGMSGEDILNQMFREINNLDIDERKKVELADAIGETDFRIVEGANERIQLSALLAKMAL 313
Cdd:PLN03025 240 FDDACDGL-KQLYDLGYSPTDIITTLFRVVKNYDMPEFLKLEYLREIGFAHMRICDGVGSLLQLSGLLAKLCL 311
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
2-312 |
1.59e-108 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 319.24 E-value: 1.59e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 2 DKP-WVEKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPHLLFSGPPGVGKTTAALCLARDLFGENWRENFLELNASD--ER 78
Cdd:PRK12402 1 DAPlWTEKYRPALLEDILGQDEVVERLSRAVDSPNLPHLLVQGPPGSGKTAAVRALARELYGDPWENNFTEFNVADffDQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 79 G------------------------IDVIRTKVKDFARTKPIgDVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFI 134
Cdd:PRK12402 81 GkkylvedprfahflgtdkrirsskIDNFKHVLKEYASYRPL-SADYKTILLDNAEALREDAQQALRRIMEQYSRTCRFI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 135 LSCNYPSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEVIDD 214
Cdd:PRK12402 160 IATRQPSKLIPPIRSRCLPLFFRAPTDDELVDVLESIAEAEGVDYDDDGLELIAYYAGGDLRKAILTLQTAALAAGEITM 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 215 EIVYKVSSRA-RPEEVKKMMELALEGKFVEARDLLYKLMVEWGMSGEDILNQMFREINNLDIDERkKVELADAIGETDFR 293
Cdd:PRK12402 240 EAAYEALGDVgTDEVIESLLDAAEAGDFTDARKTLDDLLIDEGLSGGEVLEELLRVARSRYRGDN-LARLHRLAADADAR 318
|
330
....*....|....*....
gi 256794537 294 IVEGANERIQLSALLAKMA 312
Cdd:PRK12402 319 LTDGANDRIQLEALLAELG 337
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
20-314 |
9.82e-84 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 254.13 E-value: 9.82e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 20 QDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWRE------------------NFLELNA---SDE 77
Cdd:COG0470 1 QEEAWEQLLAAAESGRLPHaLLLHGPPGIGKTTLALALARDLLCENPEGgkacgqchsrlmaagnhpDLLELNPeekSDQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 78 RGIDVIRtKVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFS 157
Cdd:COG0470 81 IGIDQIR-ELGEFLSLTPLEG-GRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 158 PLKKEDIAKKLKEiaekEGlkLTESGLEAIIYVSEGDMRKAINVLQTAAALSEVIDDeiVYKVSSRARPEEvkkMMELAL 237
Cdd:COG0470 159 PPSEEEALAWLRE----EG--VDEDALEAILRLAGGDPRAAINLLQALAGRKELLED--LAALLSRDRALE---LLDALL 227
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256794537 238 EGKFVEARDLLYKLMVEWgmsgedilnqMFreinnLDIDERKKVELADAIGETDFRIVEGANERIQLSALLAKMALM 314
Cdd:COG0470 228 KAEALELLDWLLKWLLDN----------LP-----LEYAGEDLARAYEALSEADRRLGRYANDRLLLEALLAKLGRL 289
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
5-313 |
1.17e-50 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 170.17 E-value: 1.17e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 5 WVEKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGEnwrenFLELNASDERgIDVI 83
Cdd:PHA02544 11 WEQKYRPSTIDECILPAADKETFKSIVKKGRIPNmLLHSPSPGTGKTTVAKALCNEVGAE-----VLFVNGSDCR-IDFV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 84 RTKVKDFARTKPIgDVPFKIIFLDESD-ALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFSPLKKE 162
Cdd:PHA02544 85 RNRLTRFASTVSL-TGGGKVIIIDEFDrLGLADAQRHLRSFMEAYSKNCSFIITANNKNGIIEPLRSRCRVIDFGVPTKE 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 163 D-------IAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAAlSEVIDDEIVYKVSSrarpEEVKKMMEl 235
Cdd:PHA02544 164 EqiemmkqMIVRCKGILEAEGVEVDMKVLAALVKKNFPDFRRTINELQRYAS-TGKIDAGILSEVTN----SDIDDVVE- 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 256794537 236 ALEGK-FVEARDLLYKLMVEwgmsGEDILNQMFREINNLdIDERKKVELADAIGETDFRIVEGANERIQLSALLAKMAL 313
Cdd:PHA02544 238 ALKAKdFKAVRALAPNYAND----YASFVGKLYDELYPQ-VTPPSIIRLIEIIGENNQYHGFAADQEIHLLYLLTQLML 311
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
4-286 |
3.49e-47 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 165.09 E-value: 3.49e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 4 PWVEKYRPKTLDEIVGQDEIVKRLKKYVE--KKSMPH--LLFSGPPGVGKTTAALCLARDLFGEnwrenFLELNASDERG 79
Cdd:PRK04195 3 PWVEKYRPKTLSDVVGNEKAKEQLREWIEswLKGKPKkaLLLYGPPGVGKTSLAHALANDYGWE-----VIELNASDQRT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 80 IDVIRTKVKDFARTKPIGDVPFKIIFLDESDALTPdaqNALRRTMEKYSDVCR-----FILSCNYP-SKIIPPIQSRCAI 153
Cdd:PRK04195 78 ADVIERVAGEAATSGSLFGARRKLILLDEVDGIHG---NEDRGGARAILELIKkakqpIILTANDPyDPSLRELRNACLM 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 154 FRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEVIDDEIVYKVSSRARPEEVKKMM 233
Cdd:PRK04195 155 IEFKRLSTRSIVPVLKRICRKEGIECDDEALKEIAERSGGDLRSAINDLQAIAEGYGKLTLEDVKTLGRRDREESIFDAL 234
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 256794537 234 ELALEGKFV-EARDLLYKLMVEWGMsgedilnqMFREIN-NLDIDERKKVELADA 286
Cdd:PRK04195 235 DAVFKARNAdQALEASYDVDEDPDD--------LIEWIDeNIPKEYDDPEDIARA 281
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
11-312 |
1.25e-46 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 160.36 E-value: 1.25e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 11 PKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWREN-----------FLELNASD-- 76
Cdd:COG2812 6 PQTFDDVVGQEHVVRTLKNALASGRLAHaYLFTGPRGVGKTTLARILAKALNCENGPTGepcgecescraIAAGSHPDvi 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 77 -------ERGIDVIRTkVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTME------KysdvcrFILSCNYPSKI 143
Cdd:COG2812 86 eidaeasNIGVDDIRE-LIEKVSYAPVEG-RYKVYIIDEAHMLTTEAFNALLKTLEeppphvV------FILATTEPQKL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 144 IPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLqtaaalseviDDEIVYKVssR 223
Cdd:COG2812 158 LPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIEIEPEALALIARAADGSMRDALSLL----------DQAIAFGL--L 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 224 ARPEEVKKMMELALEGKFVEARDLLYKLmVEWGMSGEDILNQM---FREI----------NNLDIDERKKVE-------- 282
Cdd:COG2812 226 DRRELLLDLLEALLAGDVAALLALAEEL-AKRGRDLKRFLDDLlslLRDLlllklgpdaeLLVNEDERERLQelarrlsp 304
|
330 340 350
....*....|....*....|....*....|....*
gi 256794537 283 -----LADAIGETDFRIVEGANERIQLSALLAKMA 312
Cdd:COG2812 305 erllrAIQILLEARRELERNVNPRLALEMLLLRLA 339
|
|
| dnaX_nterm |
TIGR02397 |
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ... |
8-273 |
3.52e-42 |
|
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274111 [Multi-domain] Cd Length: 355 Bit Score: 148.87 E-value: 3.52e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDL-------------------FGENWRE 67
Cdd:TIGR02397 7 KYRPQTFEDVIGQEHIVQTLKNAIKNGRIAHaYLFSGPRGTGKTSIARIFAKALncqngpdgepcnecesckeINSGSSL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 NFLELNASDERGIDVIRtKVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPI 147
Cdd:TIGR02397 87 DVIEIDAASNNGVDDIR-EILDNVKYAPSSG-KYKVYIIDEVHMLSKSAFNALLKTLEEPPEHVVFILATTEPHKIPATI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 148 QSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE-VIDDEIVYKVSSRARP 226
Cdd:TIGR02397 165 LSRCQRFDFKRIPLEDIVERLKKILDKEGIKIEDEALELIARAADGSLRDALSLLDQLISFGNgKITYEDVNELLGLVDD 244
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 256794537 227 EEVKKMMELALEGKFVEARDLLYKLmVEWGMSGEDILNQMFREINNL 273
Cdd:TIGR02397 245 EKLIELLEAILNKDTAEALKILDEI-LESGVDPEKFLEDLIEILRDL 290
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
4-281 |
3.75e-39 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 143.81 E-value: 3.75e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 4 PWVEKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWRE--------------- 67
Cdd:PRK14953 5 PFARKYRPKFFKEVIGQEIVVRILKNAVKLQRVSHaYIFAGPRGTGKTTIARILAKVLNCLNPQEgepcgkcencveidk 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 ----NFLELNASDERGIDVIRTkVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKI 143
Cdd:PRK14953 85 gsfpDLIEIDAASNRGIDDIRA-LRDAVSYTPIKG-KYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 144 IPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE-VIDDEIVYKVSS 222
Cdd:PRK14953 163 PPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIEYEEKALDLLAQASEGGMRDAASLLDQASTYGEgKVTIKVVEEFLG 242
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256794537 223 RARPEEVKKMMELALEGKFVEARDLL-------YKLMVEWGMSGEDILNqmfrEINNLDIDERKKV 281
Cdd:PRK14953 243 IVSQESVRKFLNLLLESDVDEAIKFLrtleekgYNLNKFWKQLEEEIRN----ILLNKSLKNPEEV 304
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
7-224 |
1.21e-35 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 132.90 E-value: 1.21e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 7 EKYRPKTLDEIVGQDEIV---KRLKKYVEKKSMPHLLFSGPPGVGKTTAALCLARDLfgenwRENFLELNASDErGIDVI 83
Cdd:PRK13342 4 ERMRPKTLDEVVGQEHLLgpgKPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGAT-----DAPFEALSAVTS-GVKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 84 RTKVKDFARTKPIGDVPfkIIFLDE--------SDALTPDaqnalrrtMEKYsdvcRFIL----SCNyPS-KIIPPIQSR 150
Cdd:PRK13342 78 REVIEEARQRRSAGRRT--ILFIDEihrfnkaqQDALLPH--------VEDG----TITLigatTEN-PSfEVNPALLSR 142
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256794537 151 CAIFRFSPLKKEDIAKKLK---EIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEVIDDEIVYKVSSRA 224
Cdd:PRK13342 143 AQVFELKPLSEEDIEQLLKralEDKERGLVELDDEALDALARLANGDARRALNLLELAALGVDSITLELLEEALQKR 219
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
8-239 |
1.09e-33 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 128.73 E-value: 1.09e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWRE------------------- 67
Cdd:PRK14962 7 KYRPKTFSEVVGQDHVKKLIINALKKNSISHaYIFAGPRGTGKTTVARILAKSLNCENRKGvepcnecracrsidegtfm 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 NFLELNASDERGIDVIRtKVKDFARTKPIgDVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPI 147
Cdd:PRK14962 87 DVIELDAASNRGIDEIR-KIRDAVGYRPM-EGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 148 QSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE-VIDDEIVYKVSSRARP 226
Cdd:PRK14962 165 ISRCQVIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFSEgKITLETVHEALGLIPI 244
|
250
....*....|...
gi 256794537 227 EEVKKMMELALEG 239
Cdd:PRK14962 245 EVVRDYINAIFNG 257
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
8-201 |
7.66e-33 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 124.60 E-value: 7.66e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLAR-------DLFGENWRENFLELNASDERG 79
Cdd:PRK14970 10 KYRPQTFDDVVGQSHITNTLLNAIENNHLAQaLLFCGPRGVGKTTCARILARkinqpgyDDPNEDFSFNIFELDAASNNS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 80 IDVIRTKVkDFARTKP-IGDvpFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFSP 158
Cdd:PRK14970 90 VDDIRNLI-DQVRIPPqTGK--YKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQIFDFKR 166
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 256794537 159 LKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINV 201
Cdd:PRK14970 167 ITIKDIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDALSI 209
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
8-219 |
2.99e-31 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 123.35 E-value: 2.99e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDL--------------------FGENWR 66
Cdd:PRK14971 10 KYRPSTFESVVGQEALTTTLKNAIATNKLAHaYLFCGPRGVGKTTCARIFAKTIncqnltadgeacnecescvaFNEQRS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 67 ENFLELNASDERGIDVIRTKVkDFARTKP-IGDvpFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIP 145
Cdd:PRK14971 90 YNIHELDAASNNSVDDIRNLI-EQVRIPPqIGK--YKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILP 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256794537 146 PIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEvidDEIVYK 219
Cdd:PRK14971 167 TILSRCQIFDFNRIQVADIVNHLQYVASKEGITAEPEALNVIAQKADGGMRDALSIFDQVVSFTG---GNITYK 237
|
|
| Rep_fac_C |
pfam08542 |
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication ... |
224-310 |
4.34e-31 |
|
Replication factor C C-terminal domain; This is the C-terminal domain of RFC (replication factor-C) protein of the clamp loader complex which binds to the DNA sliding clamp (proliferating cell nuclear antigen, PCNA). The five modules of RFC assemble into a right-handed spiral, which results in only three of the five RFC subunits (RFC-A, RFC-B and RFC-C) making contact with PCNA, leaving a wedge-shaped gap between RFC-E and the PCNA clamp-loader complex. The C-terminal is vital for the correct orientation of RFC-E with respect to RFC-A.
Pssm-ID: 462513 [Multi-domain] Cd Length: 87 Bit Score: 111.80 E-value: 4.34e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 224 ARPEEVKKMMELALEGKFVEARDLLYKLMVEWGMSGEDILNQMFREINNLDIDERKKVELADAIGETDFRIVEGANERIQ 303
Cdd:pfam08542 1 PHPEDIEEILNSCLNGDFDEAYKKVRELLVEKGYSLQDIITQLHRVVKSLDLPEEVKLELLEKLGEIEYRLSEGASEKLQ 80
|
....*..
gi 256794537 304 LSALLAK 310
Cdd:pfam08542 81 LSALLAA 87
|
|
| PRK06305 |
PRK06305 |
DNA polymerase III subunits gamma and tau; Validated |
8-254 |
7.14e-29 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180523 [Multi-domain] Cd Length: 451 Bit Score: 114.87 E-value: 7.14e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWRENF----------------- 69
Cdd:PRK06305 10 KYRPQTFSEILGQDAVVAVLKNALRFNRAAHaYLFSGIRGTGKTTLARIFAKALNCQNPTEDQepcnqcasckeissgts 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 70 ---LELNASDERGIDVIR--TKVKDFARTKPigdvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKII 144
Cdd:PRK06305 90 ldvLEIDGASHRGIEDIRqiNETVLFTPSKS----RYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIP 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 145 PPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE-VIDDEIVYKVSSR 223
Cdd:PRK06305 166 GTILSRCQKMHLKRIPEETIIDKLALIAKQEGIETSREALLPIARAAQGSLRDAESLYDYVVGLFPkSLDPDSVAKALGL 245
|
250 260 270
....*....|....*....|....*....|.
gi 256794537 224 ARPEEVKKMMELALEGKFVEARDLLYKLMVE 254
Cdd:PRK06305 246 LSQDSLYTLDEAITTQNYAQALEPVTDAMNS 276
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
8-210 |
7.30e-29 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 116.06 E-value: 7.30e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAAL-------CLARDLFGENWRENFLELNASDERG 79
Cdd:PRK14950 9 KWRSQTFAELVGQEHVVQTLRNAIAEGRVAHaYLFTGPRGVGKTSTARilakavnCTTNDPKGRPCGTCEMCRAIAEGSA 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 80 IDVIR------TKVKDfARtKPIGDVPF-------KIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPP 146
Cdd:PRK14950 89 VDVIEmdaashTSVDD-AR-EIIERVQFrpalaryKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPAT 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256794537 147 IQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE 210
Cdd:PRK14950 167 ILSRCQRFDFHRHSVADMAAHLRKIAAAEGINLEPGALEAIARAATGSMRDAENLLQQLATTYG 230
|
|
| PRK05563 |
PRK05563 |
DNA polymerase III subunits gamma and tau; Validated |
8-277 |
2.65e-28 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235505 [Multi-domain] Cd Length: 559 Bit Score: 114.20 E-value: 2.65e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWR-------------------E 67
Cdd:PRK05563 9 KWRPQTFEDVVGQEHITKTLKNAIKQGKISHaYLFSGPRGTGKTSAAKIFAKAVNCLNPPdgepcneceickaitngslM 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 NFLELNASDERGID---VIRTKVKdFARTKpigdVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKII 144
Cdd:PRK05563 89 DVIEIDAASNNGVDeirDIRDKVK-YAPSE----AKYKVYIIDEVHMLSTGAFNALLKTLEEPPAHVIFILATTEPHKIP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 145 PPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE-------------V 211
Cdd:PRK05563 164 ATILSRCQRFDFKRISVEDIVERLKYILDKEGIEYEDEALRLIARAAEGGMRDALSILDQAISFGDgkvtyedalevtgS 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 212 IDDEIVYKVSSRARPEEVKKMM----ELALEGK----FVEA-----RDLL-YKL---MVEWGMSGEDIlnQMFRE-INNL 273
Cdd:PRK05563 244 VSQEALDDLVDAIVEGDVAKALkileELLDEGKdpnrFIEDliyylRDLLlVKTspeLEILDESTEND--ELFKElSEKL 321
|
....
gi 256794537 274 DIDE 277
Cdd:PRK05563 322 DIER 325
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
8-217 |
1.92e-27 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 112.14 E-value: 1.92e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGEN------------WRE------- 67
Cdd:PRK14965 9 KYRPQTFSDLTGQEHVSRTLQNAIDTGRVAHaFLFTGARGVGKTSTARILAKALNCEQgltaepcnvcppCVEitegrsv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 NFLELNASDERGIDVIRtKVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPI 147
Cdd:PRK14965 89 DVFEIDGASNTGVDDIR-ELRENVKYLPSRS-RYKIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKVPITI 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256794537 148 QSRCAIFRFS--PLKKedIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVL-QTAAALSEVIDDEIV 217
Cdd:PRK14965 167 LSRCQRFDFRriPLQK--IVDRLRYIADQEGISISDAALALVARKGDGSMRDSLSTLdQVLAFCGDAVGDDDV 237
|
|
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
1-224 |
4.93e-27 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 109.76 E-value: 4.93e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 1 MDKPWVEKYRPKTLDEIVGQDEIV---KRLKKYVEKKSMPHLLFSGPPGVGKTTAALCLARDLfgenwRENFLELNASDE 77
Cdd:COG2256 11 ANAPLAERMRPRTLDEVVGQEHLLgpgKPLRRAIEAGRLSSMILWGPPGTGKTTLARLIANAT-----DAEFVALSAVTS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 78 rGIDVIRtKVKDFARTKPIGDVPFkIIFLDE--------SDALTPDAQN-------AlrrTMEkysdvcrfilscNyPS- 141
Cdd:COG2256 86 -GVKDIR-EVIEEARERRAYGRRT-ILFVDEihrfnkaqQDALLPHVEDgtitligA---TTE------------N-PSf 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 142 KIIPPIQSRCAIFRFSPLKKEDIAKKLKE-IAEKE------GLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE---- 210
Cdd:COG2256 147 EVNSALLSRCRVFVLKPLSEEDLEQLLERaLADDErglggyKLELDDEALEALARLADGDARRALNALELAVLSAPpdgv 226
|
250
....*....|....*
gi 256794537 211 -VIDDEIVYKVSSRA 224
Cdd:COG2256 227 iEITLELVEEALQRR 241
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
18-158 |
6.50e-27 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 102.99 E-value: 6.50e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 18 VGQDEIVKRLKKYVEKKSMPHLLFSGPPGVGKTTAALCLARDLFgeNWRENFLELNASDERGIDVIRTKVKDFARTKPIG 97
Cdd:cd00009 1 VGQEEAIEALREALELPPPKNLLLYGPPGTGKTTLARAIANELF--RPGAPFLYLNASDLLEGLVVAELFGHFLVRLLFE 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256794537 98 DV---PFKIIFLDESDALTPDAQNALRRTMEKYSDV------CRFILSCNYPS--KIIPPIQSRC-AIFRFSP 158
Cdd:cd00009 79 LAekaKPGVLFIDEIDSLSRGAQNALLRVLETLNDLridrenVRVIGATNRPLlgDLDRALYDRLdIRIVIPL 151
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
7-304 |
1.87e-26 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 109.16 E-value: 1.87e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 7 EKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWRE------------------ 67
Cdd:PRK05896 8 RKYRPHNFKQIIGQELIKKILVNAILNNKLTHaYIFSGPRGIGKTSIAKIFAKAINCLNPKDgdccnscsvcesintnqs 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 -NFLELNASDERGIDVIRTKVKDfartkpIGDVPF----KIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSK 142
Cdd:PRK05896 88 vDIVELDAASNNGVDEIRNIIDN------INYLPTtfkyKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 143 IIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEV-IDDEIVYKVS 221
Cdd:PRK05896 162 IPLTIISRCQRYNFKKLNNSELQELLKSIAKKEKIKIEDNAIDKIADLADGSLRDGLSILDQLSTFKNSeIDIEDINKTF 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 222 SRARPEEVKKMMELALEGKFVEARDLLYKLMVEwGMSGEDILNQMF------------REINNLD---IDERKKVEL-AD 285
Cdd:PRK05896 242 GLVDNNKKINLIELIQKNDIEELRNLINELESK-GINFEAFCRDLInllidllvyqktKNINLLKklsKEQLKTLNLeKQ 320
|
330
....*....|....*....
gi 256794537 286 AIGETDFRIVEGANERIQL 304
Cdd:PRK05896 321 KLLSIEFNTNFLLNNFVSL 339
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
8-205 |
3.20e-26 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 108.20 E-value: 3.20e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENW---------------REN--- 68
Cdd:PRK08451 7 KYRPKHFDELIGQESVSKTLSLALDNNRLAHaYLFSGLRGSGKTSSARIFARALVCEQGpsstpcdtciqcqsaLENrhi 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 69 -FLELNASDERGIDVIR-----TKVK-DFARtkpigdvpFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPS 141
Cdd:PRK08451 87 dIIEMDAASNRGIDDIRelieqTKYKpSMAR--------FKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256794537 142 KIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTA 205
Cdd:PRK08451 159 KLPATILSRTQHFRFKQIPQNSIISHLKTILEKEGVSYEPEALEILARSGNGSLRDTLTLLDQA 222
|
|
| PRK14963 |
PRK14963 |
DNA polymerase III subunits gamma and tau; Provisional |
7-208 |
7.92e-26 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184927 [Multi-domain] Cd Length: 504 Bit Score: 106.85 E-value: 7.92e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 7 EKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTT-------AALCLARD-----------LFGENWRE 67
Cdd:PRK14963 6 QRARPITFDEVVGQEHVKEVLLAALRQGRLGHaYLFSGPRGVGKTTtarliamAVNCSGEDpkpcgecesclAVRRGAHP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 NFLELNASDERGIDVIRtKVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPI 147
Cdd:PRK14963 86 DVLEIDAASNNSVEDVR-DLREKVLLAPLRG-GRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTI 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256794537 148 QSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAAL 208
Cdd:PRK14963 164 LSRTQHFRFRRLTEEEIAGKLRRLLEAEGREAEPEALQLVARLADGAMRDAESLLERLLAL 224
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
8-216 |
1.98e-25 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 106.72 E-value: 1.98e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWRE------------------- 67
Cdd:PRK08691 9 KWRPKTFADLVGQEHVVKALQNALDEGRLHHaYLLTGTRGVGKTTIARILAKSLNCENAQHgepcgvcqsctqidagryv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 NFLELNASDERGIDVIRtKVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPI 147
Cdd:PRK08691 89 DLLEIDAASNTGIDNIR-EVLENAQYAPTAG-KYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVTV 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256794537 148 QSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAAL--SEVIDDEI 216
Cdd:PRK08691 167 LSRCLQFVLRNMTAQQVADHLAHVLDSEKIAYEPPALQLLGRAAAGSMRDALSLLDQAIALgsGKVAENDV 237
|
|
| PRK07133 |
PRK07133 |
DNA polymerase III subunits gamma and tau; Validated |
3-206 |
2.74e-25 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235943 [Multi-domain] Cd Length: 725 Bit Score: 106.06 E-value: 2.74e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 3 KPWVEKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLA--------RDLFG------ENWRE 67
Cdd:PRK07133 6 KALYRKYRPKTFDDIVGQDHIVQTLKNIIKSNKISHaYLFSGPRGTGKTSVAKIFAnalncshkTDLLEpcqeciENVNN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 NF--LELNASDERGIDVIR---TKVKDFARTKpigdvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSK 142
Cdd:PRK07133 86 SLdiIEMDAASNNGVDEIReliENVKNLPTQS-----KYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHK 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256794537 143 IIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAA 206
Cdd:PRK07133 161 IPLTILSRVQRFNFRRISEDEIVSRLEFILEKENISYEKNALKLIAKLSSGSLRDALSIAEQVS 224
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
1-59 |
7.70e-25 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 104.92 E-value: 7.70e-25
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 256794537 1 MDKPWVEKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPHLLFSGPPGVGKttaalCLARD 59
Cdd:PRK04132 5 LEKPWVEKYRPQRLDDIVGQEHIVKRLKHYVKTGSMPHLLFAGPPGVGK-----CLTGD 58
|
|
| PRK06645 |
PRK06645 |
DNA polymerase III subunits gamma and tau; Validated |
4-243 |
1.24e-24 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 180643 [Multi-domain] Cd Length: 507 Bit Score: 103.79 E-value: 1.24e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 4 PWVEKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDL---------------------- 60
Cdd:PRK06645 10 PFARKYRPSNFAELQGQEVLVKVLSYTILNDRLAGgYLLTGIRGVGKTTSARIIAKAVncsalitenttiktceqctnci 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 61 -FGENWRENFLELNASDERGIDVIRTKVKDfARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNY 139
Cdd:PRK06645 90 sFNNHNHPDIIEIDAASKTSVDDIRRIIES-AEYKPLQG-KHKIFIIDEVHMLSKGAFNALLKTLEEPPPHIIFIFATTE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 140 PSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEVIDDEIvyk 219
Cdd:PRK06645 168 VQKIPATIISRCQRYDLRRLSFEEIFKLLEYITKQENLKTDIEALRIIAYKSEGSARDAVSILDQAASMSAKSDNII--- 244
|
250 260
....*....|....*....|....
gi 256794537 220 vssraRPEEVKKMMELALEGKFVE 243
Cdd:PRK06645 245 -----SPQVINQMLGLVDSSVIIE 263
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
8-209 |
2.12e-24 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 102.94 E-value: 2.12e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAA----LCLaRDLFGENWR-----------ENF-- 69
Cdd:PRK14964 6 KYRPSSFKDLVGQDVLVRILRNAFTLNKIPQsILLVGASGVGKTTCAriisLCL-NCSNGPTSDpcgtchncisiKNSnh 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 70 ---LELNASDERGIDVIRTKVKDfARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPP 146
Cdd:PRK14964 85 pdvIEIDAASNTSVDDIKVILEN-SCYLPISS-KFKVYIIDEVHMLSNSAFNALLKTLEEPAPHVKFILATTEVKKIPVT 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256794537 147 IQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALS 209
Cdd:PRK14964 163 IISRCQRFDLQKIPTDKLVEHLVDIAKKENIEHDEESLKLIAENSSGSMRNALFLLEQAAIYS 225
|
|
| holB |
TIGR00678 |
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ... |
25-170 |
3.27e-24 |
|
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273213 [Multi-domain] Cd Length: 188 Bit Score: 96.93 E-value: 3.27e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 25 KRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWREN-----------FLELNASDER---------GIDVI 83
Cdd:TIGR00678 2 QQLKRALEKGRLAHaYLFTGPEGVGKELLALALAKALLCEQRGGGepcgechscrlIEAGNHPDLHrlepegqsiKVDQV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 84 RTKVKDFARTKPIGdvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFSPLKKED 163
Cdd:TIGR00678 82 RELVEFLSRTPQES--GRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEA 159
|
....*..
gi 256794537 164 IAKKLKE 170
Cdd:TIGR00678 160 LLQWLIR 166
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
8-238 |
5.28e-24 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 102.43 E-value: 5.28e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWR-----ENFLELNASDE-RGI 80
Cdd:PRK14960 8 KYRPRNFNELVGQNHVSRALSSALERGRLHHaYLFTGTRGVGKTTIARILAKCLNCETGVtstpcEVCATCKAVNEgRFI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 81 DVI------RTKVKDfarTKPIGD-VP-------FKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPP 146
Cdd:PRK14960 88 DLIeidaasRTKVED---TRELLDnVPyaptqgrFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPIT 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 147 IQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE-------------VID 213
Cdd:PRK14960 165 VISRCLQFTLRPLAVDEITKHLGAILEKEQIAADQDAIWQIAESAQGSLRDALSLTDQAIAYGQgavhhqdvkemlgLID 244
|
250 260
....*....|....*....|....*
gi 256794537 214 DEIVYKVSSRARPEEVKKMMELALE 238
Cdd:PRK14960 245 RTIIYDLILAVHQNQREKVSQLLLQ 269
|
|
| PRK14969 |
PRK14969 |
DNA polymerase III subunits gamma and tau; Provisional |
8-208 |
1.28e-23 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237873 [Multi-domain] Cd Length: 527 Bit Score: 100.59 E-value: 1.28e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENW----------------RENF- 69
Cdd:PRK14969 9 KWRPKSFSELVGQEHVVRALTNALEQQRLHHaYLFTGTRGVGKTTLARILAKSLNCETGvtatpcgvcsacleidSGRFv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 70 --LELNASDERGIDVIRtKVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPI 147
Cdd:PRK14969 89 dlIEVDAASNTQVDAMR-ELLDNAQYAPTRG-RFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPVTV 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256794537 148 QSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAAL 208
Cdd:PRK14969 167 LSRCLQFNLKQMPPPLIVSHLQHILEQENIPFDATALQLLARAAAGSMRDALSLLDQAIAY 227
|
|
| HLD_clamp_RFC |
cd18140 |
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ... |
159-220 |
1.86e-22 |
|
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.
Pssm-ID: 350842 [Multi-domain] Cd Length: 63 Bit Score: 88.35 E-value: 1.86e-22
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256794537 159 LKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEVIDDEIVYKV 220
Cdd:cd18140 1 LSKEQIVKRLREICKKEGVKIDEEALEAIAEKSEGDMRKAINDLQAAAAGGGVITEEDVYEV 62
|
|
| PRK14948 |
PRK14948 |
DNA polymerase III subunit gamma/tau; |
3-212 |
4.89e-22 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237862 [Multi-domain] Cd Length: 620 Bit Score: 96.19 E-value: 4.89e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 3 KPWVEKYRPKTLDEIVGQDEIVKRLKKYVE-KKSMPHLLFSGPPGVGKTTAALCLARDLfgenwreNFLelnASDE---- 77
Cdd:PRK14948 4 EPLHHKYRPQRFDELVGQEAIATTLKNALIsNRIAPAYLFTGPRGTGKTSSARILAKSL-------NCL---NSDKptpe 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 78 --------RGI------DVIR------TKVKD---------FARTKpigdVPFKIIFLDESDALTPDAQNALRRTMEKYS 128
Cdd:PRK14948 74 pcgkcelcRAIaagnalDVIEidaasnTGVDNirelieraqFAPVQ----ARWKVYVIDECHMLSTAAFNALLKTLEEPP 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 129 DVCRFILSCNYPSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTesgLEAIIYV---SEGDMRKAINVLQTA 205
Cdd:PRK14948 150 PRVVFVLATTDPQRVLPTIISRCQRFDFRRIPLEAMVQHLSEIAEKESIEIE---PEALTLVaqrSQGGLRDAESLLDQL 226
|
....*..
gi 256794537 206 AALSEVI 212
Cdd:PRK14948 227 SLLPGPI 233
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
8-210 |
7.21e-22 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 94.49 E-value: 7.21e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPHL-LFSGPPGVGKTTAALCLARDLFGEN------WRENFLELNASDERGI 80
Cdd:PRK14961 9 KWRPQYFRDIIGQKHIVTAISNGLSLGRIHHAwLLSGTRGVGKTTIARLLAKSLNCQNgitsnpCRKCIICKEIEKGLCL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 81 DVI------RTKVKDfarTKPIGD----VP----FKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPP 146
Cdd:PRK14961 89 DLIeidaasRTKVEE---MREILDniyySPsksrFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKT 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256794537 147 IQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE 210
Cdd:PRK14961 166 ILSRCLQFKLKIISEEKIFNFLKYILIKESIDTDEYALKLIAYHAHGSMRDALNLLEHAINLGK 229
|
|
| PRK14959 |
PRK14959 |
DNA polymerase III subunits gamma and tau; Provisional |
4-210 |
2.27e-21 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184923 [Multi-domain] Cd Length: 624 Bit Score: 94.36 E-value: 2.27e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 4 PWVEKYRPKTLDEIVGQdEIVKRL--KKYVEKKSMPHLLFSGPPGVGKTTAALCLARDL------FGE--NWRE------ 67
Cdd:PRK14959 5 SLTARYRPQTFAEVAGQ-ETVKAIlsRAAQENRVAPAYLFSGTRGVGKTTIARIFAKALncetapTGEpcNTCEqcrkvt 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 -----NFLELNASDERGIDvirtkvkDFARTK-PIGDVP----FKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSC 137
Cdd:PRK14959 84 qgmhvDVVEIDGASNRGID-------DAKRLKeAIGYAPmegrYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLAT 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256794537 138 NYPSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE 210
Cdd:PRK14959 157 TEPHKFPVTIVSRCQHFTFTRLSEAGLEAHLTKVLGREGVDYDPAAVRLIARRAAGSVRDSMSLLGQVLALGE 229
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
8-209 |
3.39e-21 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 94.17 E-value: 3.39e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDL-----FGEN------------WRE-- 67
Cdd:PRK12323 9 KWRPRDFTTLVGQEHVVRALTHALEQQRLHHaYLFTGTRGVGKTTLSRILAKSLnctgaDGEGgitaqpcgqcraCTEid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 -----NFLELNASDERGIDVIrTKVKDFARTKPiGDVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSK 142
Cdd:PRK12323 89 agrfvDYIEMDAASNRGVDEM-AQLLDKAVYAP-TAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQK 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256794537 143 IIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALS 209
Cdd:PRK12323 167 IPVTVLSRCLQFNLKQMPPGHIVSHLDAILGEEGIAHEVNALRLLAQAAQGSMRDALSLTDQAIAYS 233
|
|
| PRK14957 |
PRK14957 |
DNA polymerase III subunits gamma and tau; Provisional |
8-220 |
5.70e-21 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184921 [Multi-domain] Cd Length: 546 Bit Score: 93.22 E-value: 5.70e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGE--------NWRENFLELNasDER 78
Cdd:PRK14957 9 KYRPQSFAEVAGQQHALNSLVHALETQKVHHaYLFTGTRGVGKTTLGRLLAKCLNCKtgvtaepcNKCENCVAIN--NNS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 79 GIDVI------RTKVKDfarTKPIGD----VP----FKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKII 144
Cdd:PRK14957 87 FIDLIeidaasRTGVEE---TKEILDniqyMPsqgrYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 145 PPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE-------------V 211
Cdd:PRK14957 164 VTILSRCIQLHLKHISQADIKDQLKIILAKENINSDEQSLEYIAYHAKGSLRDALSLLDQAISFCGgelkqaqikqmlgI 243
|
....*....
gi 256794537 212 IDDEIVYKV 220
Cdd:PRK14957 244 IDSEEVYSI 252
|
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
8-235 |
8.81e-21 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 92.53 E-value: 8.81e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWR------ENFLELNASDERGI 80
Cdd:PRK06647 9 KRRPRDFNSLEGQDFVVETLKHSIESNKIANaYIFSGPRGVGKTSSARAFARCLNCVNGPtpmpcgECSSCKSIDNDNSL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 81 DVIR------TKVKDFARTK-----PIGDVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQS 149
Cdd:PRK06647 89 DVIEidgasnTSVQDVRQIKeeimfPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 150 RCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE-------------VIDDEI 216
Cdd:PRK06647 169 RCQHFNFRLLSLEKIYNMLKKVCLEDQIKYEDEALKWIAYKSTGSVRDAYTLFDQVVSFSDsditleqirskmgLTGDEF 248
|
250
....*....|....*....
gi 256794537 217 VYKVSSRARPEEVKKMMEL 235
Cdd:PRK06647 249 LEKLASSILNEDAKELLCV 267
|
|
| PRK14955 |
PRK14955 |
DNA polymerase III subunits gamma and tau; Provisional |
8-252 |
5.72e-20 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184919 [Multi-domain] Cd Length: 397 Bit Score: 89.18 E-value: 5.72e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDL-------------------------- 60
Cdd:PRK14955 9 KYRPKKFADITAQEHITRTIQNSLRMGRVGHgYIFSGLRGVGKTTAARVFAKAVncqrmiddadylqevtepcgecescr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 61 -FGENWRENFLELNASDERGIDVIRTkVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNY 139
Cdd:PRK14955 89 dFDAGTSLNISEFDAASNNSVDDIRL-LRENVRYGPQKG-RYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 140 PSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVL----------------- 202
Cdd:PRK14955 167 LHKIPATIASRCQRFNFKRIPLEEIQQQLQGICEAEGISVDADALQLIGRKAQGSMRDAQSILdqviafsvesegegsir 246
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 256794537 203 -QTAAALSEVIDDEIVYKVSSRARPEEVKKMMELAlegKFV-----EARDLLYKLM 252
Cdd:PRK14955 247 yDKVAELLNYIDDEHFFAVTDAVADGDAVAMLDVA---QFVirngyDEQDFLEKLI 299
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
3-205 |
3.13e-19 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 88.19 E-value: 3.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 3 KPWVEKYRPKTLDEIVGQDEIV--KR-LKKYVEKKSMPHLLFSGPPGVGKTTAALCLARdlfgeNWRENFLELNASdERG 79
Cdd:PRK13341 16 APLADRLRPRTLEEFVGQDHILgeGRlLRRAIKADRVGSLILYGPPGVGKTTLARIIAN-----HTRAHFSSLNAV-LAG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 80 IDVIRTKVKDFA--------RTkpigdvpfkIIFLDESDALTPDAQNALRRTMEKySDVCRFILSCNYPS-KIIPPIQSR 150
Cdd:PRK13341 90 VKDLRAEVDRAKerlerhgkRT---------ILFIDEVHRFNKAQQDALLPWVEN-GTITLIGATTENPYfEVNKALVSR 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256794537 151 CAIFRFSPLKKEDIAKKLKE-IAEKEG------LKLTESGLEAIIYVSEGDMRKAINVLQTA 205
Cdd:PRK13341 160 SRLFRLKSLSDEDLHQLLKRaLQDKERgygdrkVDLEPEAEKHLVDVANGDARSLLNALELA 221
|
|
| PRK07399 |
PRK07399 |
DNA polymerase III subunit delta'; Validated |
15-236 |
1.11e-18 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236011 [Multi-domain] Cd Length: 314 Bit Score: 84.57 E-value: 1.11e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 15 DEIVGQDEIVKRLKKYVEKKSM-PHLLFSGPPGVGKTTAALCLARDLF-----GENWRENFLELNASD------------ 76
Cdd:PRK07399 4 ANLIGQPLAIELLTAAIKQNRIaPAYLFAGPEGVGRKLAALCFIEGLLsqgspSKNIRRRLEEGNHPDllwveptyqhqg 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 77 --------------ERGIDVIRTK----VKDFARTKPIgDVPFKIIFLDESDALTPDAQNALRRTMEKYSDvCRFILSCN 138
Cdd:PRK07399 84 klitaseaeeaglkRKAPPQIRLEqireIKRFLSRPPL-EAPRKVVVIEDAETMNEAAANALLKTLEEPGN-GTLILIAP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 139 YPSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKlteSGLEAIIYVSEGDMRKAINVLQTAAALSEviddEIVY 218
Cdd:PRK07399 162 SPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRLGDEEILN---INFPELLALAQGSPGAAIANIEQLQSIPP----ELLQ 234
|
250
....*....|....*...
gi 256794537 219 KVSSraRPEEVKKMMELA 236
Cdd:PRK07399 235 KLEQ--PPKSPLEALELA 250
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
19-159 |
1.16e-18 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 81.49 E-value: 1.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 19 GQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWREN-----------FLELNASD---------E 77
Cdd:pfam13177 1 GQPEAIQLLQNSLENGRLSHaYLFSGPEGVGKLELALAFAKALFCEEPGDDlpcgqcrscrrIESGNHPDlviiepegqS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 78 RGIDVIRTKVKDFARTKPIGdvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFS 157
Cdd:pfam13177 81 IKIDQIRELQKEFSKSPYEG--KKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFK 158
|
..
gi 256794537 158 PL 159
Cdd:pfam13177 159 PL 160
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
8-207 |
1.41e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 85.92 E-value: 1.41e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDL-----------------FGENWRE-- 67
Cdd:PRK14951 9 KYRPRSFSEMVGQEHVVQALTNALTQQRLHHaYLFTGTRGVGKTTVSRILAKSLncqgpdgqggitatpcgVCQACRDid 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 -----NFLELNASDERGIDVIRtKVKDFARTKPIgDVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSK 142
Cdd:PRK14951 89 sgrfvDYTELDAASNRGVDEVQ-QLLEQAVYKPV-QGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQK 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256794537 143 IIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAA 207
Cdd:PRK14951 167 VPVTVLSRCLQFNLRPMAPETVLEHLTQVLAAENVPAEPQALRLLARAARGSMRDALSLTDQAIA 231
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
8-210 |
2.03e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 85.38 E-value: 2.03e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWREN------------------ 68
Cdd:PRK14956 11 KYRPQFFRDVIHQDLAIGALQNALKSGKIGHaYIFFGPRGVGKTTIARILAKRLNCENPIGNepcnectscleitkgiss 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 69 -FLELNASDERGIDVIRtKVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPI 147
Cdd:PRK14956 91 dVLEIDAASNRGIENIR-ELRDNVKFAPMGG-KYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPETI 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256794537 148 QSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE 210
Cdd:PRK14956 169 LSRCQDFIFKKVPLSVLQDYSEKLCKIENVQYDQEGLFWIAKKGDGSVRDMLSFMEQAIVFTD 231
|
|
| PRK14954 |
PRK14954 |
DNA polymerase III subunits gamma and tau; Provisional |
8-252 |
2.25e-18 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184918 [Multi-domain] Cd Length: 620 Bit Score: 85.38 E-value: 2.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGE------NWRE------------- 67
Cdd:PRK14954 9 KYRPSKFADITAQEHITHTIQNSLRMDRVGHgYIFSGLRGVGKTTAARVFAKAVNCQrmiddpVYLQevtepcgecescr 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 --------NFLELNASDERGIDVIRTkVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNY 139
Cdd:PRK14954 89 dfdagtslNISEFDAASNNSVDDIRQ-LRENVRYGPQKG-RYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 140 PSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVL----------------- 202
Cdd:PRK14954 167 LHKIPATIASRCQRFNFKRIPLDEIQSQLQMICRAEGIQIDADALQLIARKAQGSMRDAQSILdqviafsvgseaekvia 246
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 256794537 203 -QTAAALSEVIDDEIVYKVSSRARPEEVKKMMELAlegKFV-----EARDLLYKLM 252
Cdd:PRK14954 247 yQGVAELLNYIDDEQFFDVTDAIAENDAVKMLEVA---RFVidngyDEQDFLEKLI 299
|
|
| PRK14952 |
PRK14952 |
DNA polymerase III subunits gamma/tau; |
8-219 |
4.82e-18 |
|
DNA polymerase III subunits gamma/tau;
Pssm-ID: 237866 [Multi-domain] Cd Length: 584 Bit Score: 84.55 E-value: 4.82e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDL-------------------FGENWRE 67
Cdd:PRK14952 6 KYRPATFAEVVGQEHVTEPLSSALDAGRINHaYLFSGPRGCGKTSSARILARSLncaqgptatpcgvcescvaLAPNGPG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 NF--LELNASDERGIDVIRtKVKDFARTKPiGDVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIP 145
Cdd:PRK14952 86 SIdvVELDAASHGGVDDTR-ELRDRAFYAP-AQSRYRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLP 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 256794537 146 PIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEviDDEIVYK 219
Cdd:PRK14952 164 TIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYPLVIRAGGGSPRDTLSVLDQLLAGAA--DTHVTYQ 235
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
39-159 |
1.17e-17 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 77.63 E-value: 1.17e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 39 LLFSGPPGVGKTTAALCLARDLFGenwreNFLELNASDERGIDVIRT--KVKD-FARTKPIGDvpfKIIFLDESDALTP- 114
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELGA-----PFIEISGSELVSKYVGESekRLRElFEAAKKLAP---CVIFIDEIDALAGs 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 256794537 115 ----------DAQNALRRTMEKYSDVCR---FILSCNYPSKIIPPIQSRCAIFRFSPL 159
Cdd:pfam00004 73 rgsggdsesrRVVNQLLTELDGFTSSNSkviVIAATNRPDKLDPALLGRFDRIIEFPL 130
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
8-209 |
9.63e-17 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 80.66 E-value: 9.63e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGEN------------WRE------- 67
Cdd:PRK07003 9 KWRPKDFASLVGQEHVVRALTHALDGGRLHHaYLFTGTRGVGKTTLSRIFAKALNCETgvtsqpcgvcraCREidegrfv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 NFLELNASDERGIDVIrTKVKDFARTKPIgDVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPI 147
Cdd:PRK07003 89 DYVEMDAASNRGVDEM-AALLERAVYAPV-DARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTV 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 256794537 148 QSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALS 209
Cdd:PRK07003 167 LSRCLQFNLKQMPAGHIVSHLERILGEERIAFEPQALRLLARAAQGSMRDALSLTDQAIAYS 228
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
8-207 |
4.26e-16 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 78.62 E-value: 4.26e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGE--------NWRENFLELNAS--- 75
Cdd:PRK14958 9 KWRPRCFQEVIGQAPVVRALSNALDQQYLHHaYLFTGTRGVGKTTISRILAKCLNCEkgvsanpcNDCENCREIDEGrfp 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 76 DERGIDVI-RTKVKDfaRTKPIGDVP-------FKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPI 147
Cdd:PRK14958 89 DLFEVDAAsRTKVED--TRELLDNIPyaptkgrFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTV 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 148 QSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAA 207
Cdd:PRK14958 167 LSRCLQFHLAQLPPLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRDALSLLDQSIA 226
|
|
| PRK05564 |
PRK05564 |
DNA polymerase III subunit delta'; Validated |
16-193 |
2.45e-14 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180132 [Multi-domain] Cd Length: 313 Bit Score: 72.37 E-value: 2.45e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 16 EIVGQDEIVKRLKKYVEKKSMPHL-LFSGPPGVGKTTAALCLARDLFGENWRENF---LELNASDER--GIDVIRTKVKD 89
Cdd:PRK05564 5 TIIGHENIKNRIKNSIIKNRFSHAhIIVGEDGIGKSLLAKEIALKILGKSQQREYvdiIEFKPINKKsiGVDDIRNIIEE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 90 fARTKPI-GDVpfKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFSPLKKED----I 164
Cdd:PRK05564 85 -VNKKPYeGDK--KVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIYKLNRLSKEEiekfI 161
|
170 180
....*....|....*....|....*....
gi 256794537 165 AKKLKEIAEKEglkltesgLEAIIYVSEG 193
Cdd:PRK05564 162 SYKYNDIKEEE--------KKSAIAFSDG 182
|
|
| HLD_clamp |
cd18133 |
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit ... |
159-219 |
6.37e-14 |
|
helical lid domain of clamp loader-like AAA+ proteins; Clamp loader complexes are multisubunit complexes that play an important role in DNA replication. They open sliding clamps for assembly and close them around DNA, specifically targeting them to sites where DNA synthesis is initiated and orienting them correctly for replication. The subunits belong to the clamp loader clade of AAA+ superfamily.
Pssm-ID: 350838 [Multi-domain] Cd Length: 65 Bit Score: 65.57 E-value: 6.37e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256794537 159 LKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE--VIDDEIVYK 219
Cdd:cd18133 1 LDQEQLKRRLAAIAEQEKLKLDDAALQALAYISEGDLRKALNALQRAAALGDdgKISLDRVYQ 63
|
|
| PRK09112 |
PRK09112 |
DNA polymerase III subunit delta'; Validated |
11-203 |
6.53e-14 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 169667 [Multi-domain] Cd Length: 351 Bit Score: 71.22 E-value: 6.53e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 11 PKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGEN------------------WRE---- 67
Cdd:PRK09112 19 PSENTRLFGHEEAEAFLAQAYREGKLHHaLLFEGPEGIGKATLAFHLANHILSHPdpaeapetladpdpaspvWRQiaqg 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 ---NFLELNAS-DERG--------IDVIRTKVKDFARTKPIGDvpFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFIL 135
Cdd:PRK09112 99 ahpNLLHITRPfDEKTgkfktaitVDEIRRVGHFLSQTSGDGN--WRIVIIDPADDMNRNAANAILKTLEEPPARALFIL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 256794537 136 SCNYPSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKegLKLTESGLEAIIYVSEGDMRKAINVLQ 203
Cdd:PRK09112 177 ISHSSGRLLPTIRSRCQPISLKPLDDDELKKALSHLGSS--QGSDGEITEALLQRSKGSVRKALLLLN 242
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
10-60 |
4.49e-13 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 68.62 E-value: 4.49e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 256794537 10 RPKTLDEIVGQDEIVKRLKKYVE-----KKSMPHLLFSGPPGVGKTTAALCLARDL 60
Cdd:PRK00080 20 RPKSLDEFIGQEKVKENLKIFIEaakkrGEALDHVLLYGPPGLGKTTLANIIANEM 75
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
10-60 |
5.67e-13 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 68.57 E-value: 5.67e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 256794537 10 RPKTLDEIVGQDEIVKRLKKYVE-----KKSMPHLLFSGPPGVGKTTAALCLARDL 60
Cdd:COG2255 23 RPKRLDEYIGQEKVKENLKIFIEaakkrGEALDHVLLYGPPGLGKTTLAHIIANEM 78
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
10-60 |
9.15e-13 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 64.83 E-value: 9.15e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 256794537 10 RPKTLDEIVGQDEIVKRLKKYVE-----KKSMPHLLFSGPPGVGKTTAALCLARDL 60
Cdd:pfam05496 2 RPRTLDEYIGQEKVKENLKIFIEaakqrGEALDHVLLYGPPGLGKTTLANIIANEM 57
|
|
| PRK09111 |
PRK09111 |
DNA polymerase III subunits gamma and tau; Validated |
8-252 |
1.89e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236382 [Multi-domain] Cd Length: 598 Bit Score: 67.62 E-value: 1.89e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDL-----------------FGENWRE-- 67
Cdd:PRK09111 17 KYRPQTFDDLIGQEAMVRTLTNAFETGRIAQaFMLTGVRGVGKTTTARILARALnyegpdgdggptidlcgVGEHCQAim 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 -----NFLELNASDERGIDVIRtKVKDFARTKPIGdVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSK 142
Cdd:PRK09111 97 egrhvDVLEMDAASHTGVDDIR-EIIESVRYRPVS-ARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHVKFIFATTEIRK 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 143 IIPPIQSRCAIF---RFSPlkkEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSeviddeivyk 219
Cdd:PRK09111 175 VPVTVLSRCQRFdlrRIEA---DVLAAHLSRIAAKEGVEVEDEALALIARAAEGSVRDGLSLLDQAIAHG---------- 241
|
250 260 270
....*....|....*....|....*....|...
gi 256794537 220 vSSRARPEEVKKMMELALEGKFVearDLLYKLM 252
Cdd:PRK09111 242 -AGEVTAEAVRDMLGLADRARVI---DLFEALM 270
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
12-217 |
6.65e-12 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 65.01 E-value: 6.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 12 KTLDEIVGQDEIVKRLKKYVE-----KKSMPHLLFSGPPGVGKTTAALCLARdlfgenwrenflELNASdergIDVIR-- 84
Cdd:TIGR00635 1 KLLAEFIGQEKVKEQLQLFIEaakmrQEALDHLLLYGPPGLGKTTLAHIIAN------------EMGVN----LKITSgp 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 85 --TKVKDFART----KPiGDVpfkiIFLDESDALTPDAQNALRRTMEKYS----------------DVCRFIL--SCNYP 140
Cdd:TIGR00635 65 alEKPGDLAAIltnlEE-GDV----LFIDEIHRLSPAVEELLYPAMEDFRldivigkgpsarsvrlDLPPFTLvgATTRA 139
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 256794537 141 SKIIPPIQSRCAI-FRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSEVIDDEIV 217
Cdd:TIGR00635 140 GMLTSPLRDRFGIiLRLEFYTVEELAEIVSRSAGLLNVEIEPEAALEIARRSRGTPRIANRLLRRVRDFAQVRGQKII 217
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
3-209 |
2.05e-11 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 64.59 E-value: 2.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 3 KPWVEKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-----LLFSGPPGVGKTTAALCLARDLfGENWRENF----LELN 73
Cdd:TIGR00602 72 EPWVEKYKPETQHELAVHKKKIEEVETWLKAQVLENapkriLLITGPSGCGKSTTIKILSKEL-GIQVQEWSnptlPDFQ 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 74 ASDERGIDVIRTKVKDF-------------ARTKP--IGD---VPFKIIFLDESDA---LTPDAQNALRRTmeKYSDVCR 132
Cdd:TIGR00602 151 KNDHKVTLSLESCFSNFqsqievfsefllrATNKLqmLGDdlmTDKKIILVEDLPNqfyRDTRALHEILRW--KYVSIGR 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 133 ----FILS-----------CNYPSKIIPP--IQSRCAIFR--FSPLKKEDIAKKLKEIAEKEGLKLTE-------SGLEA 186
Cdd:TIGR00602 229 cplvFIITeslegdnnqrrLLFPAETIMNkeILEEPRVSNisFNPIAPTIMKKFLNRIVTIEAKKNGEkikvpkkTSVEL 308
|
250 260
....*....|....*....|...
gi 256794537 187 IIYVSEGDMRKAINVLQTAAALS 209
Cdd:TIGR00602 309 LCQGCSGDIRSAINSLQFSSSKS 331
|
|
| HolA |
COG1466 |
DNA polymerase III, delta subunit [Replication, recombination and repair]; |
102-273 |
5.62e-10 |
|
DNA polymerase III, delta subunit [Replication, recombination and repair];
Pssm-ID: 441075 [Multi-domain] Cd Length: 305 Bit Score: 59.11 E-value: 5.62e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 102 KIIFLDESDALT--PDAQNALRRTMEKYSDVCRFILSCNYP---SKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEG 176
Cdd:COG1466 64 RLVIVRNAEFLKkpGEGLEALEAYLANPPPDTVLVLTAGKLdkrKKLFKALEKAGVVVECYPLKERELPAWIRQRLKAAG 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 177 LKLTESGLEAIIYVSEGDMRKAINVLQ---TAAALSEVIDDEIVYKVSSRARPEEVKKMMELALEGKFVEARDLLYKLMV 253
Cdd:COG1466 144 LRIDPDAAQLLAERVGGDLLALAQELEklaLYAGDGGTITLEDVEALVGDSAEFNVFDLADALLAGDAARALRILRRLLA 223
|
170 180
....*....|....*....|...
gi 256794537 254 EwgmsGED---ILNQMFREINNL 273
Cdd:COG1466 224 E----GEEpvlILAALARQFRLL 242
|
|
| PRK14949 |
PRK14949 |
DNA polymerase III subunits gamma and tau; Provisional |
8-207 |
8.61e-10 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237863 [Multi-domain] Cd Length: 944 Bit Score: 59.74 E-value: 8.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTaalcLARdLFGENwrenfleLN------AS----- 75
Cdd:PRK14949 9 KWRPATFEQMVGQSHVLHALTNALTQQRLHHaYLFTGTRGVGKTS----LAR-LFAKG-------LNceqgvtATpcgvc 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 76 -------DERGIDVI------RTKVKDfarTKPIGD-V---P----FKIIFLDESDALTPDAQNALRRTMEKYSDVCRFI 134
Cdd:PRK14949 77 sscveiaQGRFVDLIevdaasRTKVDD---TRELLDnVqyrPsrgrFKVYLIDEVHMLSRSSFNALLKTLEEPPEHVKFL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256794537 135 LSCNYPSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAA 207
Cdd:PRK14949 154 LATTDPQKLPVTVLSRCLQFNLKSLTQDEIGTQLNHILTQEQLPFEAEALTLLAKAANGSMRDALSLTDQAIA 226
|
|
| PRK07471 |
PRK07471 |
DNA polymerase III subunit delta'; Validated |
10-202 |
4.31e-09 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236022 [Multi-domain] Cd Length: 365 Bit Score: 56.96 E-value: 4.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 10 RPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLF--------GENWRENFLELNASD---- 76
Cdd:PRK07471 14 HPRETTALFGHAAAEAALLDAYRSGRLHHaWLIGGPQGIGKATLAYRMARFLLatpppggdGAVPPPTSLAIDPDHpvar 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 77 -------------ERGID----VIRTK--VKDFARTKPI-----GDVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCR 132
Cdd:PRK07471 94 riaagahgglltlERSWNekgkRLRTVitVDEVRELISFfgltaAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSL 173
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 133 FILSCNYPSKIIPPIQSRCAIFRFSPLKKEDIAKKLkeiaEKEGLKLTESGLEAIIYVSEGDMRKAINVL 202
Cdd:PRK07471 174 FLLVSHAPARLLPTIRSRCRKLRLRPLAPEDVIDAL----AAAGPDLPDDPRAALAALAEGSVGRALRLA 239
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
3-217 |
1.28e-08 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 55.69 E-value: 1.28e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 3 KPWVEKYRPKTLDEIVGQDEIVKRLKKYVE------------KKSMP-HLLFSGPPGVGKTTAALCLARDlfgenWRENF 69
Cdd:COG0464 145 EEELLELREAILDDLGGLEEVKEELRELVAlplkrpelreeyGLPPPrGLLLYGPPGTGKTLLARALAGE-----LGLPL 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 70 LELNASD---------ERGI-DVIRTkvkdfARTKPIGdvpfkIIFLDESDALTPDAQNALRRTM------------EKY 127
Cdd:COG0464 220 IEVDLSDlvskyvgetEKNLrEVFDK-----ARGLAPC-----VLFIDEADALAGKRGEVGDGVGrrvvntlltemeELR 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 128 SDVCrFILSCNYPSKIIPPIQSRCA-IFRFSPLKKEDiakkLKEIAEK--EGLKLTESG-LEAIIYVSEG----DMRkai 199
Cdd:COG0464 290 SDVV-VIAATNRPDLLDPALLRRFDeIIFFPLPDAEE----RLEIFRIhlRKRPLDEDVdLEELAEATEGlsgaDIR--- 361
|
250
....*....|....*...
gi 256794537 200 NVLQTAAALSEVIDDEIV 217
Cdd:COG0464 362 NVVRRAALQALRLGREPV 379
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
38-156 |
1.41e-08 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 53.15 E-value: 1.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 38 HLLFSGPPGVGKTTAALCLARDLFGENWRenFLELNASDERGIDVIRTKVKDFARTKPIGDV--------------PFKI 103
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGG--VIYIDGEDILEEVLDQLLLIIVGGKKASGSGelrlrlalalarklKPDV 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256794537 104 IFLDESDALTPDAQNALRR--------TMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRF 156
Cdd:smart00382 82 LILDEITSLLDAEQEALLLlleelrllLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRI 142
|
|
| PRK07940 |
PRK07940 |
DNA polymerase III subunit delta'; Validated |
15-151 |
2.45e-08 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 236134 [Multi-domain] Cd Length: 394 Bit Score: 54.53 E-value: 2.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 15 DEIVGQDEIVKRLKKYVE---------KKSMPH-LLFSGPPGVGKTTAALCLARDLFGENWRE----------NFLELNA 74
Cdd:PRK07940 5 DDLVGQEAVVAELRAAARaaradvaaaGSGMTHaWLFTGPPGSGRSVAARAFAAALQCTDPDEpgcgecracrTVLAGTH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 75 SDER---------GIDVIRTKVKDFARTKPIGdvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIP 145
Cdd:PRK07940 85 PDVRvvapeglsiGVDEVRELVTIAARRPSTG--RWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLP 162
|
....*.
gi 256794537 146 PIQSRC 151
Cdd:PRK07940 163 TIRSRC 168
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
14-240 |
7.05e-08 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 52.58 E-value: 7.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 14 LDEIVGQDEIVKRLK---KYVEKKSMP---------HLLFSGPPGVGKTTAALCLARDLfgenwRENFLELNASdergiD 81
Cdd:COG1223 1 LDDVVGQEEAKKKLKliiKELRRRENLrkfglwpprKILFYGPPGTGKTMLAEALAGEL-----KLPLLTVRLD-----S 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 82 VIRT----------KVKDFARTKPIgdvpfkIIFLDESDALTPDAQ------------NALRRTMEKYSDVCRFILSCNY 139
Cdd:COG1223 71 LIGSylgetarnlrKLFDFARRAPC------VIFFDEFDAIAKDRGdqndvgevkrvvNALLQELDGLPSGSVVIAATNH 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 140 PSKIIPPIQSRCAIF-RFSPLKKEDIAKKLKEIAEKEGLKLTESgLEAIIYVSEG----DMRKainVLQTAAALSEVIDD 214
Cdd:COG1223 145 PELLDSALWRRFDEViEFPLPDKEERKEILELNLKKFPLPFELD-LKKLAKKLEGlsgaDIEK---VLKTALKKAILEDR 220
|
250 260
....*....|....*....|....*.
gi 256794537 215 EIVYKVSSRARPEEVKKMMELALEGK 240
Cdd:COG1223 221 EKVTKEDLEEALKQRKERKKEPKKEG 246
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
8-210 |
7.18e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 53.72 E-value: 7.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLFGE------------NWREnflelna 74
Cdd:PRK07994 9 KWRPQTFAEVVGQEHVLTALANALDLGRLHHaYLFSGTRGVGKTTIARLLAKGLNCEtgitatpcgecdNCRE------- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 75 SDE-RGIDVI------RTKVKDF-----------ARTKpigdvpFKIIFLDESDALTPDAQNALRRTME------Kysdv 130
Cdd:PRK07994 82 IEQgRFVDLIeidaasRTKVEDTrelldnvqyapARGR------FKVYLIDEVHMLSRHSFNALLKTLEeppehvK---- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 131 crFILSCNYPSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE 210
Cdd:PRK07994 152 --FLLATTDPQKLPVTILSRCLQFHLKALDVEQIRQQLEHILQAEQIPFEPRALQLLARAADGSMRDALSLTDQAIASGN 229
|
|
| PRK05707 |
PRK05707 |
DNA polymerase III subunit delta'; Validated |
33-193 |
1.10e-07 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180215 [Multi-domain] Cd Length: 328 Bit Score: 52.40 E-value: 1.10e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 33 KKSMPH-LLFSGPPGVGKTTAALCLARDLFGE--------------------NWRENF-LELNASDER-GIDVIRTKVKD 89
Cdd:PRK05707 18 RGRHPHaYLLHGPAGIGKRALAERLAAALLCEapqgggacgsckgcqllragSHPDNFvLEPEEADKTiKVDQVRELVSF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 90 FARTKPIGDvpFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFSPLKKED----IA 165
Cdd:PRK05707 98 VVQTAQLGG--RKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQACPLPSNEEslqwLQ 175
|
170 180 190
....*....|....*....|....*....|..
gi 256794537 166 KKLKEIAEKEGLK-LTESG---LEAIIYVSEG 193
Cdd:PRK05707 176 QALPESDERERIElLTLAGgspLRALQLHEQG 207
|
|
| HLD_clamp_pol_III_gamma_tau |
cd18137 |
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit ... |
159-220 |
1.44e-07 |
|
helical lid domain of DNA polymerase III subunits gamma and tau; DNA polymerase III subunit gamma/tau is part of the DNA polymerase III holoenzyme. Gamma and tau subunits are isoforms, both containing the helical lid domain. Gamma interacts with the delta subunit to transfer the beta subunit on the DNA while tau serves as a scaffold to help in the dimerization of the core complex. Both are members of the clamp-loader clade of the AAA+ superfamily.
Pssm-ID: 350839 [Multi-domain] Cd Length: 65 Bit Score: 47.88 E-value: 1.44e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 256794537 159 LKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE-VIDDEIVYKV 220
Cdd:cd18137 1 ISVEDIVGRLAHILEKEGIEIEDEALELIARAAEGSMRDALSLLDQAIAFGGgRVTLDDVREM 63
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
8-150 |
1.65e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 52.68 E-value: 1.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 8 KYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-LLFSGPPGVGKTTAALCLARDLfgeNWRE------------------- 67
Cdd:PRK07764 8 RYRPATFAEVIGQEHVTEPLSTALDSGRINHaYLFSGPRGCGKTSSARILARSL---NCVEgptstpcgecdscvalapg 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 68 -----NFLELNASDERGIDVIRtKVKDFARTKPIGDvPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSK 142
Cdd:PRK07764 85 gpgslDVTEIDAASHGGVDDAR-ELRERAFFAPAES-RYKIFIIDEAHMVTPQGFNALLKIVEEPPEHLKFIFATTEPDK 162
|
....*...
gi 256794537 143 IIPPIQSR 150
Cdd:PRK07764 163 VIGTIRSR 170
|
|
| PRK08699 |
PRK08699 |
DNA polymerase III subunit delta'; Validated |
32-175 |
7.06e-07 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181538 [Multi-domain] Cd Length: 325 Bit Score: 49.87 E-value: 7.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 32 EKKSMPH-LLFSGPPGVGKTTAALCLARDL--------------------FGENWRENFLELNA-SDER---------GI 80
Cdd:PRK08699 16 HWERRPNaWLFAGKKGIGKTAFARFAAQALlcetpapghkpcgecmschlFGQGSHPDFYEITPlSDEPengrkllqiKI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 81 DVIRtKVKDFAR-TKPIGDVpfKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFSPL 159
Cdd:PRK08699 96 DAVR-EIIDNVYlTSVRGGL--RVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTIKSRCRKMVLPAP 172
|
170
....*....|....*...
gi 256794537 160 KKEDIAKKLKE--IAEKE 175
Cdd:PRK08699 173 SHEEALAYLRErgVAEPE 190
|
|
| CDC6 |
COG1474 |
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair]; |
9-261 |
8.30e-07 |
|
Cdc6-related protein, AAA superfamily ATPase [Replication, recombination and repair];
Pssm-ID: 441083 [Multi-domain] Cd Length: 389 Bit Score: 49.85 E-value: 8.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 9 YRPktlDEIVGQDEIVKRLKKYVE---KKSMP-HLLFSGPPGVGKTTAALCLARDLfgenwrenfleLNASDERGIDV-- 82
Cdd:COG1474 23 YVP---DRLPHREEEIEELASALRpalRGERPsNVLIYGPTGTGKTAVAKYVLEEL-----------EEEAEERGVDVrv 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 83 -------IRTK-------VKDFARTKPI---GdVPFK-----------------IIFLDESDALTPDAQN----ALRRTM 124
Cdd:COG1474 89 vyvncrqASTRyrvlsriLEELGSGEDIpstG-LSTDelfdrlyealderdgvlVVVLDEIDYLVDDEGDdllyQLLRAN 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 125 EKYSDV-CRFILSCN---YPSKIIPPIQSR--CAIFRFSPLKKEDIAKKLKEIAEkEGLK---LTESGLE---AIIYVSE 192
Cdd:COG1474 168 EELEGArVGVIGISNdleFLENLDPRVKSSlgEEEIVFPPYDADELRDILEDRAE-LAFYdgvLSDEVIPliaALAAQEH 246
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256794537 193 GDMRKAINVLQTAAAL-----SEVIDDEIVYKVSSRARPEEVKKMME-LALEGKfveardLLYKLMVEWGMSGED 261
Cdd:COG1474 247 GDARKAIDLLRVAGEIaeregSDRVTEEHVREAREKIERDRLLEVLRgLPTHEK------LVLLAIAELLKDGED 315
|
|
| RecA-like_ClpB_Hsp104-like |
cd19499 |
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ... |
15-126 |
1.62e-06 |
|
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410907 [Multi-domain] Cd Length: 178 Bit Score: 47.56 E-value: 1.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 15 DEIVGQDEIVKRLKKYV---------EKKSMPHLLFSGPPGVGKTTAALCLARDLFGENwrENFLELNAS--DERGiDVI 83
Cdd:cd19499 11 ERVVGQDEAVKAVSDAIrraraglsdPNRPIGSFLFLGPTGVGKTELAKALAELLFGDE--DNLIRIDMSeyMEKH-SVS 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 256794537 84 RTK------VKDFARTKPIGDV---PFKIIFLDESDALTPDAQNALRRTMEK 126
Cdd:cd19499 88 RLIgappgyVGYTEGGQLTEAVrrkPYSVVLLDEIEKAHPDVQNLLLQVLDD 139
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
3-68 |
2.32e-06 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 47.26 E-value: 2.32e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256794537 3 KPWVEKYRPKTLDEIVGQDEIVKRLKKYVEKKSMPH-----LLFSGPPGVGKTTAALCLARDLfGENWREN 68
Cdd:pfam03215 7 EQWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENakhriLLISGPSGCGKSTVIKELSKEL-GPKYREW 76
|
|
| PRK07132 |
PRK07132 |
DNA polymerase III subunit delta'; Validated |
94-200 |
2.40e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180855 [Multi-domain] Cd Length: 299 Bit Score: 48.18 E-value: 2.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 94 KPIGDVPFKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFS-PLKKEDIAKKLKEIA 172
Cdd:PRK07132 84 SSFVQSQKKILIIKNIEKTSNSLLNALLKTIEEPPKDTYFLLTTKNINKVLPTIVSRCQVFNVKePDQQKILAKLLSKNK 163
|
90 100
....*....|....*....|....*...
gi 256794537 173 EKEGLKLTesgleAIIYVSEGDMRKAIN 200
Cdd:PRK07132 164 EKEYNWFY-----AYIFSNFEQAEKYIN 186
|
|
| PRK06090 |
PRK06090 |
DNA polymerase III subunit delta'; Validated |
101-184 |
2.55e-06 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180394 [Multi-domain] Cd Length: 319 Bit Score: 48.26 E-value: 2.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 101 FKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFSPLKKEDIAKKLKEiaekEGLKLT 180
Cdd:PRK06090 109 YRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWVVTPPSTAQAMQWLKG----QGITVP 184
|
....
gi 256794537 181 ESGL 184
Cdd:PRK06090 185 AYAL 188
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
14-150 |
2.85e-06 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 46.51 E-value: 2.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 14 LDEIVGQDEIVKRLKKYVEKKSMPhLLFSGPPGVGKTTAALCLARDLfgenwRENFLELNASD--ERGIDVIRTKVK--- 88
Cdd:cd19481 5 LREAVEAPRRGSRLRRYGLGLPKG-ILLYGPPGTGKTLLAKALAGEL-----GLPLIVVKLSSllSKYVGESEKNLRkif 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256794537 89 DFARTKpigdvPFKIIFLDESDALTPD------------AQNALRRTMEKY---SDVCrFILSCNYPSKIIPPIQSR 150
Cdd:cd19481 79 ERARRL-----APCILFIDEIDAIGRKrdssgesgelrrVLNQLLTELDGVnsrSKVL-VIAATNRPDLLDPALLRP 149
|
|
| PRK08769 |
PRK08769 |
DNA polymerase III subunit delta'; Validated |
39-177 |
1.54e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181551 [Multi-domain] Cd Length: 319 Bit Score: 45.72 E-value: 1.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 39 LLFSGPPGVGKTTAALCLARDLFGENWRE---------------------NFLELNASDERGIDVIRTKVKD----FART 93
Cdd:PRK08769 29 LLICGPEGLGKRAVALALAEHVLASGPDPaaaqrtrqliaagthpdlqlvSFIPNRTGDKLRTEIVIEQVREisqkLALT 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 94 KPIGDVpfKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFRFS-PLKKEDIA----KKL 168
Cdd:PRK08769 109 PQYGIA--QVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSRCQRLEFKlPPAHEALAwllaQGV 186
|
....*....
gi 256794537 169 KEIAEKEGL 177
Cdd:PRK08769 187 SERAAQEAL 195
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
159-217 |
1.61e-05 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 42.23 E-value: 1.61e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 159 LKKEDI------AKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE-----VIDDEIV 217
Cdd:cd18139 1 LSEEDLekllkrALEDKERGGDRKVTIDDEALELLAEAADGDARSALNLLELAVLSAEedggiVITLEDL 70
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
37-166 |
2.02e-05 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 46.34 E-value: 2.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 37 PHLLFSGPPGVGKTTAALCLARDLFGENWREN-----FLELN--ASDERGIDVIRTKVKDFArTKPIGDV-------PFK 102
Cdd:COG5635 181 KRLLILGEPGSGKTTLLRYLALELAERYLDAEdpipiLIELRdlAEEASLEDLLAEALEKRG-GEPEDALerllrngRLL 259
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 256794537 103 IIF--LDE--SDALTPDAQNALRRTMEKYSDvCRFILSC---NYPSKIIppiqSRCAIFRFSPLKKEDIAK 166
Cdd:COG5635 260 LLLdgLDEvpDEADRDEVLNQLRRFLERYPK-ARVIITSrpeGYDSSEL----EGFEVLELAPLSDEQIEE 325
|
|
| AAA_3 |
pfam07726 |
ATPase family associated with various cellular activities (AAA); This Pfam entry includes some ... |
38-125 |
2.05e-05 |
|
ATPase family associated with various cellular activities (AAA); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 429622 [Multi-domain] Cd Length: 131 Bit Score: 43.32 E-value: 2.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 38 HLLFSGPPGVGKTTAALCLARDLFGENWRENFL-ELNASDERGIDVIRTKVKDFaRTKPiGDVPFKIIFLDESDALTPDA 116
Cdd:pfam07726 1 HVLLEGVPGLAKTLLVRTLARSLGLDFRRIQFTpDLLPSDITGTEVFDQKTREF-EFRP-GPVFANVLLADEINRAPPKT 78
|
....*....
gi 256794537 117 QNALRRTME 125
Cdd:pfam07726 79 QSALLEAMQ 87
|
|
| PRK06871 |
PRK06871 |
DNA polymerase III subunit delta'; Validated |
79-165 |
2.15e-05 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 180738 [Multi-domain] Cd Length: 325 Bit Score: 45.50 E-value: 2.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 79 GIDVIR---TKVKDFARTKpiGDvpfKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRCAIFR 155
Cdd:PRK06871 88 GVDQVReinEKVSQHAQQG--GN---KVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQTWL 162
|
90
....*....|
gi 256794537 156 FSPlKKEDIA 165
Cdd:PRK06871 163 IHP-PEEQQA 171
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
2-112 |
2.41e-05 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 45.38 E-value: 2.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 2 DKPWVEKYRPKTLDEIVGQDEIVKRLKKYVEK------------KSMPH-LLFSGPPGVGKTTaalcLARDLFGEnWREN 68
Cdd:COG1222 65 GTAVPAESPDVTFDDIGGLDEQIEEIREAVELplknpelfrkygIEPPKgVLLYGPPGTGKTL----LAKAVAGE-LGAP 139
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 256794537 69 FLELNASD---------ERGIDvirtKVKDFARTK-PIgdvpfkIIFLDESDAL 112
Cdd:COG1222 140 FIRVRGSElvskyigegARNVR----EVFELAREKaPS------IIFIDEIDAI 183
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
17-128 |
3.84e-05 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 44.39 E-value: 3.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 17 IVGQDEIVKRL------KKyvekksmpHLLFSGPPGVGKTTAALCLARDLFGENWRENFLE-LNASDERGIDVIRTKVKD 89
Cdd:COG0714 14 YVGQEELIELVliallaGG--------HLLLEGVPGVGKTTLAKALARALGLPFIRIQFTPdLLPSDILGTYIYDQQTGE 85
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 256794537 90 FARTK-PIGDVpfkIIFLDESDALTPDAQNALRRTMEKYS 128
Cdd:COG0714 86 FEFRPgPLFAN---VLLADEINRAPPKTQSALLEAMEERQ 122
|
|
| T7SS_EccA |
TIGR03922 |
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ... |
14-205 |
4.95e-05 |
|
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 188437 [Multi-domain] Cd Length: 557 Bit Score: 44.84 E-value: 4.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 14 LDEIVGQDEI---VKRLKKYVE------KKSMP------HLLFSGPPGVGKTTAALCLARDLFGENW--RENFLELNASD 76
Cdd:TIGR03922 275 LAEQIGLERVkrqVAALKSSTAmalaraERGLPvaqtsnHMLFAGPPGTGKTTIARVVAKIYCGLGVlrKPLVREVSRAD 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 77 ERGIDVIRTKVKdfarTKPIGDVPF-KIIFLDESDAL------TPD-----AQNALRRTMEKYSDVCRFILScNYPSKII 144
Cdd:TIGR03922 355 LIGQYIGESEAK----TNEIIDSALgGVLFLDEAYTLvetgygQKDpfgleAIDTLLARMENDRDRLVVIGA-GYRKDLD 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 145 ------PPIQSRCA----IFRFSPLKKEDIAKKlkeIAEKEGLKLTESGLEAII-----------YVSEGDMRKAINVLQ 203
Cdd:TIGR03922 430 kflevnEGLRSRFTrvieFPSYSPDELVEIARR---MATERDSVLDDAAADALLeaattlaqdttPDANGDLRRGLDIAG 506
|
..
gi 256794537 204 TA 205
Cdd:TIGR03922 507 NG 508
|
|
| COG2842 |
COG2842 |
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ... |
40-210 |
1.25e-04 |
|
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];
Pssm-ID: 442090 [Multi-domain] Cd Length: 254 Bit Score: 42.63 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 40 LFSGPPGVGKTTAA-----------------LCLARDLFgenwRENFLELNASDERG-----IDVIRTKVKDFARTkpig 97
Cdd:COG2842 54 VVYGESGVGKTTAAreyanrnpnviyvtaspSWTSKELL----EELAEELGIPAPPGtiadlRDRILERLAGTGRL---- 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 98 dvpfkiIFLDESDALTPDAQNALRRTMEKYSdvCRFILSCN--YPSKI--IPPIQSRCA-IFRFSPLKKEDIAKKLKEIA 172
Cdd:COG2842 126 ------LIIDEADHLKPKALEELRDIHDETG--VGVVLIGMerLPAKLkrYEQLYSRIGfWVEFKPLSLEDVRALAEAWG 197
|
170 180 190
....*....|....*....|....*....|....*...
gi 256794537 173 EKEGLKLtesgLEAIIYVSEGDMRKAINVLQTAAALSE 210
Cdd:COG2842 198 ELTDPDL----LELLHRITRGNLRRLDRTLRLAARAAK 231
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
40-136 |
1.39e-04 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 41.50 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 40 LFSGPPGVGKTTAALCLArdlfgENWRENFLELNASD---------ERGIDVIRTKVKDFARTkpigdvpfkIIFLDESD 110
Cdd:cd19511 31 LLYGPPGCGKTLLAKALA-----SEAGLNFISVKGPElfskyvgesERAVREIFQKARQAAPC---------IIFFDEID 96
|
90 100
....*....|....*....|....*.
gi 256794537 111 ALTPdaqnalRRTMEKYSDVCRFILS 136
Cdd:cd19511 97 SLAP------RRGQSDSSGVTDRVVS 116
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
16-132 |
1.42e-04 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 41.72 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 16 EIVGQDEIVKRLKKYVEK---KSMPHLLFSGPPGVGKTTAALCLARDLFGENWRenFLELNASDERGIDVIRTKVKDFAR 92
Cdd:pfam13191 1 RLVGREEELEQLLDALDRvrsGRPPSVLLTGEAGTGKTTLLRELLRALERDGGY--FLRGKCDENLPYSPLLEALTREGL 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 256794537 93 TKPIGDVPFKIIF----------LDESDALTPDAQNALRRTMEKYSDVCR 132
Cdd:pfam13191 79 LRQLLDELESSLLeawraalleaLAPVPELPGDLAERLLDLLLRLLDLLA 128
|
|
| AAA_14 |
pfam13173 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
39-136 |
3.34e-04 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 463799 [Multi-domain] Cd Length: 128 Bit Score: 39.88 E-value: 3.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 39 LLFSGPPGVGKTTAALCLARDLFGenwRENFLELNASDERGIDVIRTKVKDFARTKPIGDVPFkiIFLDESDALtPDAQN 118
Cdd:pfam13173 5 LVITGPRQVGKTTLLLQLIKELLP---PENILYINLDDPRLLKLADFELLELFLELLYPGKTY--LFLDEIQRV-PDWEL 78
|
90
....*....|....*...
gi 256794537 119 ALRRTMEKYSDvCRFILS 136
Cdd:pfam13173 79 ALKRLYDDGPN-GRVILT 95
|
|
| RecA-like_NVL_r1-like |
cd19518 |
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
39-126 |
3.43e-04 |
|
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 40.47 E-value: 3.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 39 LLFSGPPGVGKTTAALCLARDLfgenwRENFLELNA----------SDERgidvIRTKVKDFARTKPIgdvpfkIIFLDE 108
Cdd:cd19518 37 VLLHGPPGCGKTMLANAIAGEL-----KVPFLKISAteivsgvsgeSEEK----IRELFDQAISNAPC------IVFIDE 101
|
90
....*....|....*...
gi 256794537 109 SDALTPDAQNAlRRTMEK 126
Cdd:cd19518 102 IDAITPKRESA-QREMER 118
|
|
| PRK07993 |
PRK07993 |
DNA polymerase III subunit delta'; Validated |
79-151 |
3.84e-04 |
|
DNA polymerase III subunit delta'; Validated
Pssm-ID: 181190 [Multi-domain] Cd Length: 334 Bit Score: 41.59 E-value: 3.84e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 256794537 79 GIDVIRT---KVKDFARtkpIGDVpfKIIFLDESDALTPDAQNALRRTMEKYSDVCRFILSCNYPSKIIPPIQSRC 151
Cdd:PRK07993 89 GVDAVREvteKLYEHAR---LGGA--KVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRC 159
|
|
| DEXHc_RE |
cd17926 |
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family ... |
20-96 |
1.67e-03 |
|
DEXH-box helicase domain of DEAD-like helicase restriction enzyme family proteins; This family is composed of helicase restriction enzymes and similar proteins such as TFIIH basal transcription factor complex helicase XPB subunit. These proteins are part of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350684 [Multi-domain] Cd Length: 146 Bit Score: 38.06 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 20 QDEIVKRLKKYVEKKsmpHLLFSGPPGVGKTTAALCLARDLFGEN-------------WRENFLELNASDERGIdvIRTK 86
Cdd:cd17926 5 QEEALEAWLAHKNNR---RGILVLPTGSGKTLTALALIAYLKELRtlivvptdalldqWKERFEDFLGDSSIGL--IGGG 79
|
90
....*....|
gi 256794537 87 VKDFARTKPI 96
Cdd:cd17926 80 KKKDFDDANV 89
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
38-120 |
1.71e-03 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 38.04 E-value: 1.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 38 HLLFSGPPGVGKTTAALCLARDLFGENW----------RENFLELNASDERGIDVIRTKVKDFARTKpigdvpfKIIFLD 107
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVfyvqltrdttEEDLFGRRNIDPGGASWVDGPLVRAAREG-------EIAVLD 73
|
90
....*....|...
gi 256794537 108 ESDALTPDAQNAL 120
Cdd:pfam07728 74 EINRANPDVLNSL 86
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
39-115 |
1.79e-03 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 38.43 E-value: 1.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 39 LLFSGPPGVGKTTAALCLARDLfgenwRENFLELNASD---------ERGIDVIRTKVKDFARTkpigdvpfkIIFLDES 109
Cdd:cd19503 37 VLLHGPPGTGKTLLARAVANEA-----GANFLSISGPSivskylgesEKNLREIFEEARSHAPS---------IIFIDEI 102
|
....*.
gi 256794537 110 DALTPD 115
Cdd:cd19503 103 DALAPK 108
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
38-136 |
1.99e-03 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 37.71 E-value: 1.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 38 HLLFSGPPGVGKTTAALCLARDLFGEN-------------WRE------NFLELNASDERGIDVIRTKVKDFARTKPIGD 98
Cdd:pfam13401 7 ILVLTGESGTGKTTLLRRLLEQLPEVRdsvvfvdlpsgtsPKDllrallRALGLPLSGRLSKEELLAALQQLLLALAVAV 86
|
90 100 110
....*....|....*....|....*....|....*...
gi 256794537 99 VpfkiIFLDESDALTPDAQNALRRTMEKYSDVCRFILS 136
Cdd:pfam13401 87 V----LIIDEAQHLSLEALEELRDLLNLSSKLLQLILV 120
|
|
| COG1373 |
COG1373 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
23-136 |
2.26e-03 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440984 [Multi-domain] Cd Length: 405 Bit Score: 39.54 E-value: 2.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 23 IVKRLKKYVEKKSMphLLFSGPPGVGKTTAALCLARDLfgenwrENFLELNASDERGIDVIRTKVKDF-ARTKPIGDVPf 101
Cdd:COG1373 9 ILDKLLKLLDNRKA--VVITGPRQVGKTTLLKQLAKEL------ENILYINLDDPRLRALAEEDPDDLlEALKELYPGK- 79
|
90 100 110
....*....|....*....|....*....|....*.
gi 256794537 102 KIIFLDE-SDAltPDAQNALRRTMEKYSDvCRFILS 136
Cdd:COG1373 80 TYLFLDEiQRV--PEWEDALKRLVDDGRN-GRFILT 112
|
|
| holA |
TIGR01128 |
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) ... |
69-308 |
2.64e-03 |
|
DNA polymerase III, delta subunit; DNA polymerase III delta (holA) and delta prime (holB) subunits are distinct proteins encoded by separate genes. The delta prime subunit (holB) exhibits sequence homology to the tau and gamma subunits (dnaX), but the delta subunit (holA) does not demonstrate this same homology with dnaX. The delta, delta prime, gamma, chi and psi subunits form the gamma complex subassembly of DNA polymerase III holoenzyme, which couples ATP to assemble the ring-shaped beta subunit around DNA forming a DNA sliding clamp. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273455 [Multi-domain] Cd Length: 302 Bit Score: 38.78 E-value: 2.64e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 69 FLELNASDERGIDVIRTKVKDFARTKPIgdvpF---KIIFLDESDALT-PDAQNALRRTMEKYSDVCRFILSCNYPSKII 144
Cdd:TIGR01128 16 FDEFNVFRIDGEEFDWNQLLEEAQTLPL----FserRLVELRNPEGKPgAKGLKALEEYLANPPPDTLLLIEAPKLDKRK 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 145 PPIQ-----SRCAIFRFSPLKKEDIAKKLKEIAEKEGLKLTESGLEAIIYVSEGDMRKAINVLQTAAALSE--VIDDEIV 217
Cdd:TIGR01128 92 KLTKwlkalKNAEIVECKTPKEQELPRWIQARLKKLGLRIDPDAVQLLAELVEGNLLAIAQELEKLALYAPdgKITLEDV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 218 YKVSSRARPEEVKKMMELALEGKFVEARDLLYKLMVEwgmsGED------ILNQMFREINNLDIDERKKV---ELADAIG 288
Cdd:TIGR01128 172 EEAVSDSARFNVFDLTDALLEGKAARALRILKGLLGE----GEEplillaLLQRQLRLLLQLKRLAQQGGplaQLASKLG 247
|
250 260
....*....|....*....|..
gi 256794537 289 ETDFRI--VEGANERIQLSALL 308
Cdd:TIGR01128 248 IWPYRRklALKALRRLSLAKLE 269
|
|
| PRK06835 |
PRK06835 |
DNA replication protein DnaC; Validated |
23-60 |
3.29e-03 |
|
DNA replication protein DnaC; Validated
Pssm-ID: 235871 [Multi-domain] Cd Length: 329 Bit Score: 38.73 E-value: 3.29e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 256794537 23 IVKRLKKYVEKKSMPH--LLFSGPPGVGKTTAALCLARDL 60
Cdd:PRK06835 168 ILEKCKNFIENFDKNNenLLFYGNTGTGKTFLSNCIAKEL 207
|
|
| PTZ00112 |
PTZ00112 |
origin recognition complex 1 protein; Provisional |
6-205 |
3.84e-03 |
|
origin recognition complex 1 protein; Provisional
Pssm-ID: 240274 [Multi-domain] Cd Length: 1164 Bit Score: 39.20 E-value: 3.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 6 VEKYRPKTLDEIvgqDEIVKRLKKYVEKKSMPHLLF-SGPPGVGKTTAALCLARDLFGENWRENFLELNASDERGIDVIR 84
Cdd:PTZ00112 753 VPKYLPCREKEI---KEVHGFLESGIKQSGSNQILYiSGMPGTGKTATVYSVIQLLQHKTKQKLLPSFNVFEINGMNVVH 829
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 85 TKV-------KDFARTKPIGDVPFKII-----------------FLDESDALTPDAQNALRRTMEKYSDV-CRFIL---- 135
Cdd:PTZ00112 830 PNAayqvlykQLFNKKPPNALNSFKILdrlfnqnkkdnrnvsilIIDEIDYLITKTQKVLFTLFDWPTKInSKLVLiais 909
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256794537 136 -SCNYPSKIIPPIQSRCAIFR--FSPLKKEDIAKKLKEIAE--KEGLKLTESGLEA--IIYVSeGDMRKAINVLQTA 205
Cdd:PTZ00112 910 nTMDLPERLIPRCRSRLAFGRlvFSPYKGDEIEKIIKERLEncKEIIDHTAIQLCArkVANVS-GDIRKALQICRKA 985
|
|
| RecA-like_FtsH |
cd19501 |
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ... |
13-112 |
6.68e-03 |
|
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410909 [Multi-domain] Cd Length: 171 Bit Score: 36.83 E-value: 6.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 13 TLDEIVGQDEIVKRLKKYVEKKSMPH------------LLFSGPPGVGKTTaalcLARDLFGENwRENFLELNASD--ER 78
Cdd:cd19501 2 TFKDVAGCEEAKEELKEVVEFLKNPEkftklgakipkgVLLVGPPGTGKTL----LAKAVAGEA-GVPFFSISGSDfvEM 76
|
90 100 110
....*....|....*....|....*....|....*
gi 256794537 79 GIDVIRTKVKD-FARTKpigDVPFKIIFLDESDAL 112
Cdd:cd19501 77 FVGVGASRVRDlFEQAK---KNAPCIVFIDEIDAV 108
|
|
| Kti12 |
COG4088 |
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) ... |
39-93 |
7.00e-03 |
|
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) [Translation, ribosomal structure and biogenesis, Defense mechanisms];
Pssm-ID: 443264 [Multi-domain] Cd Length: 179 Bit Score: 37.01 E-value: 7.00e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 256794537 39 LLFSGPPGVGKTTAALCLARDLFGENW----------RENFLELNASDERGIDVIRTKVKDFART 93
Cdd:COG4088 7 LILTGPPGSGKTTFAKALAQRLYAEGIavallhsddfRRFLVNESFPKETYEEVVEDVRTTTADN 71
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
40-176 |
8.90e-03 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 36.59 E-value: 8.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 40 LFSGPPGVGKTTAALCLA------RDLFGENWRE---NFLELNAsdERGIDVIRTKVK------DFARTKPIGDVPFKII 104
Cdd:pfam13481 37 LLAGAPGTGKTTLALDLAaavatgKPWLGGPRVPeqgKVLYVSA--EGPADELRRRLRaagadlDLPARLLFLSLVESLP 114
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 256794537 105 --FLDESDALTPDAQNALRRTMEKYSDVcRFIlscnypskIIPPIQSrcaIFRFSPLKKEDIA---KKLKEIAEKEG 176
Cdd:pfam13481 115 lfFLDRGGPLLDADVDALEAALEEVEDP-DLV--------VIDPLAR---ALGGDENSNSDVGrlvKALDRLARRTG 179
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
40-126 |
9.73e-03 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 37.19 E-value: 9.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 256794537 40 LFSGPPGVGKTTAALCLA------RDLFGenWRE---NFLELNAsdERGIDVIRTKVKDF--ARTKPIGDVPFKIIFLDE 108
Cdd:COG3598 17 LLAGPPGTGKSFLALQLAaavaagGPWLG--RRVppgKVLYLAA--EDDRGELRRRLKALgaDLGLPFADLDGRLRLLSL 92
|
90
....*....|....*....
gi 256794537 109 SDALTPDA-QNALRRTMEK 126
Cdd:COG3598 93 AGDLDDTDdLEALERAIEE 111
|
|
| |
