|
Name |
Accession |
Description |
Interval |
E-value |
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
28-407 |
7.59e-174 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 490.45 E-value: 7.59e-174
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 28 VIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAFIA 107
Cdd:cd00751 1 VIVSAVRTPIGR-FGGALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGEGQNPARQAALLAGLPESVPATT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 108 VNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMStnyRNPKVAPK-----------IDEHLADDEQMEKCLIPMGITN 176
Cdd:cd00751 80 VNRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMS---RAPYLLPKarrggrlglntLDGMLDDGLTDPFTGLSMGITA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 177 ENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSiirnsDGTEKEIIVDTDEGPREGVTAESLSKLRPAF- 255
Cdd:cd00751 157 ENVAEKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVEV-----PGRKGPVVVDRDEGPRPDTTLEKLAKLKPAFk 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 256 -DGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEIN 334
Cdd:cd00751 232 kDGTVTAGNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKRAGLTLDDIDLIEIN 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 255722703 335 EAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLKP--GQIGLTSMCIGSGMGSASILVR 407
Cdd:cd00751 312 EAFAAQALACLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRrgGRYGLATMCIGGGQGAAMVIER 386
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
29-405 |
1.26e-167 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 474.79 E-value: 1.26e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 29 IVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAFIAV 108
Cdd:TIGR01930 1 IVAAARTPIGK-FGGSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQQNIARQAALLAGLPESVPAYTV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 109 NRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTN----YRNPKVAP-----KIDEHLADDEQMEKCLIPMGITNENV 179
Cdd:TIGR01930 80 NRQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVpygvPRSLRWGVkpgnaELEDARLKDLTDANTGLPMGVTAENL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 180 ASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNsdgteKEIIVDTDEGPREGVTAESLSKLRPAF--DG 257
Cdd:TIGR01930 160 AKKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVTVKGRK-----GPVTVSSDEGIRPNTTLEKLAKLKPAFdpDG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 258 TTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEINEAF 337
Cdd:TIGR01930 235 TVTAGNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKKAGLSISDIDLFEINEAF 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 338 AAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLK--PGQIGLTSMCIGSGMGSASIL 405
Cdd:TIGR01930 315 AAQVLACIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKrrGGRYGLATMCIGGGQGAAVIL 384
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
24-408 |
8.33e-162 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 462.70 E-value: 8.33e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 24 PDDVVIVAAYRTAIGKGFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAG-ATEHRGACLAAGIPYT 102
Cdd:PLN02287 45 GDDVVIVAAYRTPICKAKRGGFKDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVVGTVLAPGSQrANECRMAAFYAGFPET 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 103 AAFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTNYRN--PKVAPKIdehlADDEQMEKCLIPMGITNENVA 180
Cdd:PLN02287 125 VPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTNPMAweGGVNPRV----ESFSQAQDCLLPMGITSENVA 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 181 SQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSD-GTEKEIIVDTDEGPREGVTAESLSKLRPAF--DG 257
Cdd:PLN02287 201 ERFGVTREEQDQAAVESHRKAAAATASGKFKDEIVPVHTKIVDPKtGEEKPIVISVDDGIRPNTTLADLAKLKPVFkkNG 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 258 TTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEINEAF 337
Cdd:PLN02287 281 TTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAVAIPAAVKAAGLELDDIDLFEINEAF 360
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 255722703 338 AAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLK----PGQIGLTSMCIGSGMGSASILVRE 408
Cdd:PLN02287 361 ASQFVYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATLLHEMKrrgkDCRFGVVSMCIGTGMGAAAVFERG 435
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
25-405 |
1.46e-157 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 449.52 E-value: 1.46e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 25 DDVVIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAA 104
Cdd:COG0183 2 REVVIVDAVRTPFGR-FGGALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAGQGQNPARQAALLAGLPESVP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 105 FIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMStnyRNPKVAPKIDEHLADDEQMEKCLI-----------PMG 173
Cdd:COG0183 81 AVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMS---RAPMLLPKARWGYRMNAKLVDPMInpgltdpytglSMG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 174 ITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRsiIRNSDGtekEIIVDTDEGPREGVTAESLSKLRP 253
Cdd:COG0183 158 ETAENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVE--VPDRKG---EVVVDRDEGPRPDTTLEKLAKLKP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 254 AF--DGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVF 331
Cdd:COG0183 233 AFkkDGTVTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKALARAGLTLDDIDLI 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 255722703 332 EINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLK--PGQIGLTSMCIGSGMGSASIL 405
Cdd:COG0183 313 EINEAFAAQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELErrGGRYGLATMCIGGGQGIALII 388
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
24-407 |
1.46e-134 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 391.05 E-value: 1.46e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 24 PDDVVIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTA 103
Cdd:PRK05790 1 MKDVVIVSAARTPIGK-FGGALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAGAGQNPARQAALKAGLPVEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 104 AFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMStnyRNPKVAPKI-DEHLADDEQMEKCLI-----------P 171
Cdd:PRK05790 80 PALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMS---QAPHVLPGSrWGQKMGDVELVDTMIhdgltdafngyH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 172 MGITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSDgtekEIIVDTDEGPREGVTAESLSKL 251
Cdd:PRK05790 157 MGITAENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVTIKQRKGD----PVVVDTDEHPRPDTTAESLAKL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 252 RPAF--DGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDID 329
Cdd:PRK05790 233 RPAFdkDGTVTAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRKALEKAGWSLADLD 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 330 VFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLKP--GQIGLTSMCIGSGMGSASILVR 407
Cdd:PRK05790 313 LIEINEAFAAQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRrgAKKGLATLCIGGGQGVALIVER 392
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
26-407 |
2.73e-118 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 349.69 E-value: 2.73e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGKGFKGSFRSVQSEFILAEFLKEFIKKTK-VDPSLIEDVAMGNVLNQAA-GATEHRGACLAAGIPYTA 103
Cdd:PRK09052 7 DAYIVAATRTPVGKAPRGMFKNTRPDDLLAHVLRSAVAQVPgLDPKLIEDAIVGCAMPEAEqGLNVARIGALLAGLPNSV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 104 AFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMST-----NyrNPKVAPKI---DEHLAddeqmekclIP--MG 173
Cdd:PRK09052 87 GGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMvpmmgN--KPSMSPAIfarDENVG---------IAygMG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 174 ITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSDGTEKEI-----IVDTDEGPREGVTAESL 248
Cdd:PRK09052 156 LTAEKVAEQWKVSREDQDAFALESHQKAIAAQQAGEFKDEITPYEITERFPDLATGEVdvktrTVDLDEGPRADTSLEGL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 249 SKLRPAFD--GTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVE 326
Cdd:PRK09052 236 AKLKPVFAnkGSVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEAIPAALKQAGLKQD 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 327 DIDVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLL--KPGQIGLTSMCIGSGMGSASI 404
Cdd:PRK09052 316 DLDWIELNEAFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLrrTNLKYGMVTMCVGTGMGAAGI 395
|
...
gi 255722703 405 LVR 407
Cdd:PRK09052 396 FER 398
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
28-404 |
2.45e-116 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 344.43 E-value: 2.45e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 28 VIVAAYRTAIGKGFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQA-AGATEHRGACLAAGIPYTAAFI 106
Cdd:PRK07661 5 VIVAGARTPVGKAKKGSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMPEAeQGLNMARNIGALAGLPYTVPAI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 107 AVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTNYRNPKVaPKIDEHLAddEQMEKCLIPMGITNENVASQFNIS 186
Cdd:PRK07661 85 TINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVPMMGHV-VRPNPRLV--EAAPEYYMGMGHTAEQVAVKYGIS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 187 RERQDEFAAKSYNKAAKAVASGAFKQEILPI----RSIIRNSDGTEKEIIVDTDEGPREGVTAESLSKLRPAF--DGTTT 260
Cdd:PRK07661 162 REDQDAFAVRSHQRAAKALAEGKFADEIVPVdvtlRTVGENNKLQEETITFSQDEGVRADTTLEILGKLRPAFnvKGSVT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 261 AGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEINEAFAAQ 340
Cdd:PRK07661 242 AGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGLFELNEAFASQ 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 255722703 341 CLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLK--PGQIGLTSMCIGSGMGSASI 404
Cdd:PRK07661 322 SIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKrrNEQFGIVTMCIGGGMGAAGV 387
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
24-407 |
2.36e-108 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 323.84 E-value: 2.36e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 24 PDDVVIVAAYRTAIGKGFKGSFRSVQSEFILAEFLKEFIKKT-KVDPSLIEDVAMGNV---LNQaaGATEHRGACLAAGI 99
Cdd:PRK08947 1 MEDVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNpALDPAEIDDIIWGCVqqtLEQ--GFNIARNAALLAGI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 100 PYTAAFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTNYRNPKV--APKIDEHLADDEQMekclipMGITNE 177
Cdd:PRK08947 79 PHSVPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVPMNHGVdfHPGLSKNVAKAAGM------MGLTAE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 178 NVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSiiRNSDGTEKeiIVDTDEGPREGVTAESLSKLRPAFD- 256
Cdd:PRK08947 153 MLGKMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPTEG--HDADGVLK--LFDYDEVIRPETTVEALAALRPAFDp 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 257 --GTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEIN 334
Cdd:PRK08947 229 vnGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVFELN 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 255722703 335 EAFAAQ---CLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLL--KPGQIGLTSMCIGSGMGSASILVR 407
Cdd:PRK08947 309 EAFAAQslpCLKDLGLLDKMDEKVNLNGGAIALGHPLGCSGARISTTLLNLMerKDAQFGLATMCIGLGQGIATVFER 386
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
27-280 |
5.69e-108 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 318.48 E-value: 5.69e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 27 VVIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAFI 106
Cdd:pfam00108 1 VVIVSAARTPFGS-FGGSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAGEGQNPARQAALKAGIPDSAPAV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 107 AVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTNYRNPKVAPkIDEHLADDEQMEKCLIP-----------MGIT 175
Cdd:pfam00108 80 TINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALPTDA-RSGLKHGDEKKHDLLIPdgltdafngyhMGLT 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 176 NENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSDGTekeiiVDTDEGPREGVTAESLSKLRPAF 255
Cdd:pfam00108 159 AENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVTVKGRKGKPT-----VDKDEGIRPPTTAEPLAKLKPAF 233
|
250 260
....*....|....*....|....*..
gi 255722703 256 D--GTTTAGNASQVSDGAAAVLLMKRS 280
Cdd:pfam00108 234 DkeGTVTAGNASPINDGAAAVLLMSES 260
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
26-407 |
8.86e-108 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 322.68 E-value: 8.86e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGkGFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNqaagaTEHRGACLA------AGI 99
Cdd:PRK09051 4 EVVVVSGVRTAIG-TFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIP-----TEPRDMYLSrvaainAGV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 100 PYTAAFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMStnyRNPKVAPKI-------DEHLADdeQMEKCL--- 169
Cdd:PRK09051 78 PQETPAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMS---RAPYLLPAArwgarmgDAKLVD--MMVGALhdp 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 170 ---IPMGITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRsiIRNSDGtekEIIVDTDEGPREGVTAE 246
Cdd:PRK09051 153 fgtIHMGVTAENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVE--IKTRKG---EVVFDTDEHVRADTTLE 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 247 SLSKLRPAF---DGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGL 323
Cdd:PRK09051 228 DLAKLKPVFkkeNGTVTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQKALERAGL 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 324 TVEDIDVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLK--PGQIGLTSMCIGSGMGS 401
Cdd:PRK09051 308 TVADLDVIEANEAFAAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQriGGRYALVTMCIGGGQGI 387
|
....*.
gi 255722703 402 ASILVR 407
Cdd:PRK09051 388 AAIFER 393
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
26-407 |
3.07e-102 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 308.81 E-value: 3.07e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTK-VDPSLIEDVAMGNVlNQAAGATEH--RGACLAAGIPYT 102
Cdd:PRK09050 3 EAFICDAIRTPIGR-YGGALSSVRADDLGAVPLKALMARNPgVDWEAVDDVIYGCA-NQAGEDNRNvaRMSALLAGLPVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 103 AAFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMStnyRNPKVAPKIDEHLADDEQMEKCLI------------ 170
Cdd:PRK09050 81 VPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMS---RAPFVMGKADSAFSRQAEIFDTTIgwrfvnplmkaq 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 171 ----PMGITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSDgtekEIIVDTDEGPREGVTAE 246
Cdd:PRK09050 158 ygvdSMPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVTIPQKKGD----PVVVDRDEHPRPETTLE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 247 SLSKLRPAF--DGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLT 324
Cdd:PRK09050 234 ALAKLKPVFrpDGTVTAGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMGIGPAPATRKLLARLGLT 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 325 VEDIDVFEINEAFAAQCLYSAEQVNVPE--EKLNINGGAIALGHPLGETGARQYATIIPLLKP--GQIGLTSMCIGSGMG 400
Cdd:PRK09050 314 IDQFDVIELNEAFAAQGLAVLRQLGLADddARVNPNGGAIALGHPLGMSGARLVLTALHQLERtgGRYALCTMCIGVGQG 393
|
....*..
gi 255722703 401 SASILVR 407
Cdd:PRK09050 394 IALAIER 400
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
26-404 |
4.39e-102 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 308.24 E-value: 4.39e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGKGFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAA-GATEHRGACLAAGIPYTAA 104
Cdd:PRK07108 3 EAVIVSTARTPLAKSWRGAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMGCANPEGAtGANIARQIALRAGLPVTVP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 105 FIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTnyrnpkVAPKIDEHLADDEQMEK----CLIPMGITNENVA 180
Cdd:PRK07108 83 GMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESISC------VQNEMNRHMLREGWLVEhkpeIYWSMLQTAENVA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 181 SQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSDGT-----EKEIIVDTDEGPREGVTAESLSKLRPAF 255
Cdd:PRK07108 157 KRYGISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITVTAGVADKAtgrlfTKEVTVSADEGIRPDTTLEGVSKIRSAL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 256 DG-TTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEIN 334
Cdd:PRK07108 237 PGgVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAGLKVDDIDLWELN 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 255722703 335 EAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGAR--QYATIIPLLKPGQIGLTSMCIGSGMGSASI 404
Cdd:PRK07108 317 EAFAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARltGHALIEGKRRGAKYVVVTMCIGGGQGAAGL 388
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
26-407 |
1.13e-100 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 305.00 E-value: 1.13e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGKGFKGSFRSVQSEFILAEFLKEFIKKT-KVDPSLIEDVAMGnvLNQAAGATEH---RGACLAAGIPY 101
Cdd:PRK07851 3 EAVIVSTARSPIGRAFKGSLKDMRPDDLAAQMVRAALDKVpALDPTDIDDLMLG--CGLPGGEQGFnmaRVVAVLLGYDF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 102 TAAfIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMST----------NYRNPKVA------------------- 152
Cdd:PRK07851 81 LPG-TTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSRfakgnsdslpDTKNPLFAeaqartaaraeggaeawhd 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 153 PKIDEHLADdeqmekCLIPMGITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSiirnSDGTekeiI 232
Cdd:PRK07851 160 PREDGLLPD------VYIAMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPVTL----PDGT----V 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 233 VDTDEGPREGVTAESLSKLRPAF--DGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGP 310
Cdd:PRK07851 226 VSTDDGPRAGTTYEKVSQLKPVFrpDGTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGLGP 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 311 AYAIPEVLKRTGLTVEDIDVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLK--PGQI 388
Cdd:PRK07851 306 VEASKQALARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLNNLQthDKTF 385
|
410
....*....|....*....
gi 255722703 389 GLTSMCIGSGMGSASILVR 407
Cdd:PRK07851 386 GLETMCVGGGQGMAMVLER 404
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
26-407 |
1.78e-98 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 299.21 E-value: 1.78e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAF 105
Cdd:PRK06205 3 DAVICEPVRTPVGR-FGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPAIGRVAALDAGLPVTVPG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 106 IAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMS------TNYRNPKVAPKIDEHLADDE-----QMEKCLIPMGI 174
Cdd:PRK06205 82 MQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSnvefytTDMRWGVRGGGVQLHDRLARgretaGGRRFPVPGGM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 175 --TNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSDGTekeiIVDTDEGPREGVTAESLSKLR 252
Cdd:PRK06205 162 ieTAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVTVPQRKGDPT----VVDRDEHPRADTTLESLAKLR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 253 PAF-----DGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVED 327
Cdd:PRK06205 238 PIMgkqdpEATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKALARAGLTLDD 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 328 IDVFEINEAFAAQCLYSAEQVNVPE---EKLNINGGAIALGHPLGETGARQYATIIPLLK--PGQIGLTSMCIGSGMGSA 402
Cdd:PRK06205 318 IDLIELNEAFAAQVLAVLKEWGFGAddeERLNVNGSGISLGHPVGATGGRILATLLRELQrrQARYGLETMCIGGGQGLA 397
|
....*
gi 255722703 403 SILVR 407
Cdd:PRK06205 398 AVFER 402
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
26-407 |
1.54e-95 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 291.41 E-value: 1.54e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAF 105
Cdd:PRK05656 3 DVVIVAATRTAIGS-FQGSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAGAGQNPARQAAIKAGLPHSVPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 106 IAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMS-TNYRNPKV--------APKIDEHLADDEQMEKCLIPMGITN 176
Cdd:PRK05656 82 MTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSlAPYVLPGArtglrmghAQLVDSMITDGLWDAFNDYHMGITA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 177 ENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSDgtekEIIVDTDEGPREGVTAESLSKLRPAF- 255
Cdd:PRK05656 162 ENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPILIPQRKGE----PLAFATDEQPRAGTTAESLAKLKPAFk 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 256 -DGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEIN 334
Cdd:PRK05656 238 kDGSVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDLIEAN 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 255722703 335 EAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLL--KPGQIGLTSMCIGSGMGSASILVR 407
Cdd:PRK05656 318 EAFAAQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMirRDAKKGLATLCIGGGQGVALAIER 392
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
28-407 |
2.92e-94 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 288.15 E-value: 2.92e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 28 VIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAFIA 107
Cdd:PRK08235 5 VIVSAARTPFGK-FGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGGQGQIPSRQAARAAGIPWEVQTET 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 108 VNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTNyrnPKVAPK------------IDEHLADDEQMEKCLIPMGIT 175
Cdd:PRK08235 84 VNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMSNA---PYILPGarwgyrmgdnevIDLMVADGLTCAFSGVHMGVY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 176 NENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSDgtekEIIVDTDEGPREGVTAESLSKLRPAF 255
Cdd:PRK08235 161 GGEVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVTIPQRKGD----PIVVAKDEAPRKDTTIEKLAKLKPVF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 256 D--GTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEI 333
Cdd:PRK08235 237 DktGTITAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKTGKTVEDIDLFEI 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 255722703 334 NEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLKP--GQIGLTSMCIGSGMGSAsILVR 407
Cdd:PRK08235 317 NEAFAAVALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRrgGGIGIAAICSGGGQGDA-VLIE 391
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
27-402 |
6.59e-90 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 276.91 E-value: 6.59e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 27 VVIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAFI 106
Cdd:PRK06633 5 VYITHAKRTAFGS-FMGSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVITGGSGQNPARQTLIHAGIPKEVPGY 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 107 AVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTNYRNPKV---APKIDEHLADDEQMEKCL-----IPMGITNEN 178
Cdd:PRK06633 84 TINKVCGSGLKSVALAANSIMTGDNEIVIAGGQENMSLGMHGSYIragAKFGDIKMVDLMQYDGLTdvfsgVFMGITAEN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 179 VASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSDGtekeiIVDTDEGPREGVTAESLSKLRPAFD-- 256
Cdd:PRK06633 164 ISKQFNISRQEQDEFALSSHKKAAKAQLAGIFKDEILPIEVTIKKTTS-----LFDHDETVRPDTSLEILSKLRPAFDkn 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 257 GTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEINEA 336
Cdd:PRK06633 239 GVVTAGNASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKALSKAGWSVNDLEVIEVNEA 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 255722703 337 FAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLKPGQI--GLTSMCIGSGMGSA 402
Cdd:PRK06633 319 FAAQSIYVNREMKWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAkkGLVTLCIGGGMGMA 386
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
26-407 |
4.51e-89 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 275.05 E-value: 4.51e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGkGFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAF 105
Cdd:PLN02644 2 DVCIVGVARTPIG-GFLGSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVLSANLGQAPARQAALGAGLPPSTIC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 106 IAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTNyrnPKVAPKIDE--HLADDEQMEKCL----------IPMG 173
Cdd:PLN02644 81 TTVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNA---PKYLPEARKgsRLGHDTVVDGMLkdglwdvyndFGMG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 174 ITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRsiiRNSDGTEKEIIVDTDEGPREgVTAESLSKLRP 253
Cdd:PLN02644 158 VCAELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVE---VPGGRGRPSVIVDKDEGLGK-FDPAKLRKLRP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 254 AFD---GTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDV 330
Cdd:PLN02644 234 SFKedgGSVTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKHAGLEASQVDY 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 255722703 331 FEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLL--KPGQIGLTSMCIGSGMGSASILVR 407
Cdd:PLN02644 314 YEINEAFSVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLrsKNGKYGVAGICNGGGGASAIVVEL 392
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
26-407 |
4.62e-88 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 272.53 E-value: 4.62e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGKGFK-GSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQA-AGATEHRGACLAAGIPYTA 103
Cdd:PRK08242 3 EAYIYDAVRTPRGKGKKdGSLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGdQGADIARTAVLAAGLPETV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 104 AFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMStnyRNPKVAPKIDEHLADDEQMEKCLIPMGITNENVASQF 183
Cdd:PRK08242 83 PGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMS---RVPMGSDGGAWAMDPSTNFPTYFVPQGISADLIATKY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 184 NISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIirnsDGTekeIIVDTDEGPREGVTAESLSKLRPAFDG------ 257
Cdd:PRK08242 160 GFSREDVDAYAVESQQRAAAAWAEGYFAKSVVPVKDQ----NGL---TILDHDEHMRPGTTMESLAKLKPSFAMmgemgg 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 258 -----------------TTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKR 320
Cdd:PRK08242 233 fdavalqkypeverinhVHHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPATRKALAK 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 321 TGLTVEDIDVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLL--KPGQIGLTSMCIGSG 398
Cdd:PRK08242 313 AGLTVDDIDLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELerRGKRTALITLCVGGG 392
|
....*....
gi 255722703 399 MGSASILVR 407
Cdd:PRK08242 393 MGIATIIER 401
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
26-407 |
2.72e-87 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 270.50 E-value: 2.72e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVlNQAAGATEH--RGACLAAGIPYTA 103
Cdd:PRK08131 3 DAYIYDGLRSPFGR-HAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCT-NQAGEDSRNvaRNALLLAGLPVTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 104 AFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMStnyRNPKVAPKIDEHLADDEQMEKCLI------------- 170
Cdd:PRK08131 81 PGQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMS---RAPFVMGKAESAFSRDAKVFDTTIgarfpnpkivaqy 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 171 ---PMGITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIrSIIRNSDGTEKeiIVDTDEGPREGVTAES 247
Cdd:PRK08131 158 gndSMPETGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPI-EVPQGRKLPPK--LVAEDEHPRPSSTVEA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 248 LSKLRPAFD-GTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVE 326
Cdd:PRK08131 235 LTKLKPLFEgGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPVEAIKKALARAGLTLD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 327 DIDVFEINEAFAAQCLYSAEQVNVP--EEKLNINGGAIALGHPLGETGARQYATIIPLLK--PGQIGLTSMCIGSGMGSA 402
Cdd:PRK08131 315 DMDIIEINEAFASQVLGCLKGLGVDfdDPRVNPNGGAIAVGHPLGASGARLALTAARELQrrGKRYAVVSLCIGVGQGLA 394
|
....*
gi 255722703 403 SILVR 407
Cdd:PRK08131 395 MVIER 399
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
25-408 |
9.52e-87 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 268.90 E-value: 9.52e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 25 DDVVIVAAYRTAIGKGF-----KGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVL----NQAAGAtehRGACL 95
Cdd:PRK06445 2 EDVYLVDFARTAFSRFRpkdpqKDVFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALqvgeNWLYGG---RHPIF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 96 AAGIPYTAAFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTN--YRNPKVAPKIdEHLADDEQMEKCL---I 170
Cdd:PRK06445 79 LARLPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTpmGDNPHIEPNP-KLLTDPKYIEYDLttgY 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 171 PMGITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSiirNSDGteKEIIVDTDEGPREGVTAESLSK 250
Cdd:PRK06445 158 VMGLTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIEV---EVEG--KKKVVDVDQSVRPDTSLEKLAK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 251 LRPAF--DGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDI 328
Cdd:PRK06445 233 LPPAFkpDGVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPASKKALEKAGLSVKDI 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 329 DVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATI--IPLLKPGQIGLTSMCIGSGMGSASILV 406
Cdd:PRK06445 313 DLWEINEAFAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLarQLQIKGKDYGVATLCVGGGQGGAVVLE 392
|
..
gi 255722703 407 RE 408
Cdd:PRK06445 393 RV 394
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
28-407 |
5.47e-77 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 243.48 E-value: 5.47e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 28 VIVAAYRTAIGKGfKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVlNQAAGATEH--RGACLAAGIPYTAAF 105
Cdd:PRK07850 5 VIVEAVRTPIGKR-NGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCV-TQAGEQSNNitRTAWLHAGLPYHVGA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 106 IAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTNYRNPKVAPKIDEHLADD------EQMEKClipmgitnENV 179
Cdd:PRK07850 83 TTIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMSRVPLGANAGPGRGLPRPDSwdidmpNQFEAA--------ERI 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 180 ASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIIRNSDG--TEKEIIVDTDEGPREgVTAESLSKLRPAFD- 256
Cdd:PRK07850 155 AKRRGITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQAPVLDEEGqpTGETRLVTRDQGLRD-TTMEGLAGLKPVLEg 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 257 GTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEINEA 336
Cdd:PRK07850 234 GIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKAGMKIGDIDLVEINEA 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 255722703 337 FAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLK--PGQIGLTSMCIGSGMGSASILVR 407
Cdd:PRK07850 314 FASVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELErtDKSTALITMCAGGALSTGTIIER 386
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
25-402 |
2.68e-71 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 229.39 E-value: 2.68e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 25 DDVVIVAAYRTAIGkGFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAA 104
Cdd:PRK06954 7 DPIVIASAARTPMA-AFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLPAGQGQAPARQAALGAGLPLSVG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 105 FIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMsTNyrNPKVAPK------------IDEHLAD--DEQMEKCLI 170
Cdd:PRK06954 86 CTTVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESM-TN--APYLLPKarggmrmghgqvLDHMFLDglEDAYDKGRL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 171 pMGITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIrsiirNSDGTEKEIIVDTDEGPREgVTAESLSK 250
Cdd:PRK06954 163 -MGTFAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPV-----TVAGKKGDTVIDRDEQPFK-ANPEKIPT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 251 LRPAF--DGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDI 328
Cdd:PRK06954 236 LKPAFskTGTVTAANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRAAEV 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 255722703 329 DVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLKP--GQIGLTSMCIGSGMGSA 402
Cdd:PRK06954 316 DLFEINEAFAVVTMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRArgGKRGVASLCIGGGEATA 391
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
68-408 |
2.88e-69 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 224.90 E-value: 2.88e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 68 DPSLIEDVAMGNVLNQAAGATEHRGACLAAGI-PYTAAFiAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMS--- 143
Cdd:PRK08170 45 APDDLDEVILGCAMPSPDEANIARVVALRLGCgEKVPAW-TVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMShap 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 144 ---------------------------TNYRNPKVAPKIDehladdeqMEKCL------IPMGITNENVASQFNISRERQ 190
Cdd:PRK08170 124 llfsekmvrwlagwyaaksigqklaalGKLRPSYLAPVIG--------LLRGLtdpvvgLNMGQTAEVLAHRFGITREQM 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 191 DEFAAKSYNKAAKAVASGAFKqEILPIRSiirnSDGTekeiIVDTDEGPREGVTAESLSKLRPAFD---GTTTAGNASQV 267
Cdd:PRK08170 196 DAYAARSHQRLAAAQAEGRLK-EVVPLFD----RDGK----FYDHDDGVRPDSSMEKLAKLKPFFDrpyGRVTAGNSSQI 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 268 SDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEINEAFAAQ---CL-- 342
Cdd:PRK08170 267 TDGACWLLLASEEAVKKYGLPPLGRIVDSQWAALDPSQMGLGPVHAATPLLQRHGLTLEDLDLWEINEAFAAQvlaCLaa 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 343 -----YSAEQVNVP-------EEKLNINGGAIALGHPLGETGARQYATIIPLLKP--GQIGLTSMCIGSGMGSASILVRE 408
Cdd:PRK08170 347 wadeeYCREQLGLDgalgeldRERLNVDGGAIALGHPVGASGARIVLHLLHALKRrgTKRGIAAICIGGGQGGAMLLERV 426
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
28-402 |
9.51e-69 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 221.56 E-value: 9.51e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 28 VIVAAYRTAIGKGfKGSFRSVQSEFILAEFLKEFIKKTkvdPSLIEDVAMGNVLnqAAGATEHRGACLAAGIPYTAAFIA 107
Cdd:PRK06690 4 VIVEAKRTPIGKK-NGMLKDYEVQQLAAPLLTFLSKGM---EREIDDVILGNVV--GPGGNVARLSALEAGLGLHIPGVT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 108 VNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTN--YRNPKVAPkidEHLADDEqmekclipMGITNENVASQFNI 185
Cdd:PRK06690 78 IDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSpfQNRARFSP---ETIGDPD--------MGVAAEYVAERYNI 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 186 SRERQDEFAAKSYNKAAKAVASGAFKQEILPIrsiirnsDGTEKEIIVdtdegpREGVTAESLSKLRPAFD--GTTTAGN 263
Cdd:PRK06690 147 TREMQDEYACLSYKRTLQALEKGYIHEEILSF-------NGLLDESIK------KEMNYERIIKRTKPAFLhnGTVTAGN 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 264 ASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEINEAFAAQCLY 343
Cdd:PRK06690 214 SCGVNDGACAVLVMEEGQARKLGYKPVLRFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDYFEINEAFASKVVA 293
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 255722703 344 SAEQVNVPEEKLNINGGAIALGHPLGETGArqyATIIPLL-----KPGQIGLTSMCIGSGMGSA 402
Cdd:PRK06690 294 CAKELQIPYEKLNVNGGAIALGHPYGASGA---MLVTRLFyqakrEDMKYGIATLGIGGGIGLA 354
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
26-400 |
1.16e-68 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 222.19 E-value: 1.16e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGKgFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAF 105
Cdd:PRK06366 3 DVYIVSAKRTAIGK-FGRSFSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAGVGQNPAGQAAYHAGLPFGVTK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 106 IAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTNyrnPKVAP---------------KIDEHLADDEQMEKCLI 170
Cdd:PRK06366 82 YTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNA---PFLLPsdlrwgpkhllhknyKIDDAMLVDGLIDAFYF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 171 P-MGITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSIirnsdgtekeiivDTDEGPREgVTAESLS 249
Cdd:PRK06366 159 EhMGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFNDL-------------DRDEGIRK-TTMEDLA 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 250 KLRPAFD--GTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVED 327
Cdd:PRK06366 225 KLPPAFDknGILTAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIPATRKLLEKQNKSIDY 304
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 255722703 328 IDVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLKPGQI--GLTSMCIGSGMG 400
Cdd:PRK06366 305 YDLVEHNEAFSIASIIVRDQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMktGLATLCHGGGGA 379
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
23-408 |
3.11e-68 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 222.17 E-value: 3.11e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 23 NPDDVVIVAAYRTAIGKGfKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIP-Y 101
Cdd:PRK08963 3 QGDRIAIVSGLRTPFAKQ-ATAFHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQMPEAPNIAREIVLGTGMNvH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 102 TAAFiAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMStnyrnpkVAP-----KIDEHLADDEQME---------- 166
Cdd:PRK08963 82 TDAY-SVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSS-------VLPigvskKLARALVDLNKARtlgqrlklfs 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 167 ----KCLIP-------------MGITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEIL-----PIRSIIrns 224
Cdd:PRK08963 154 rlrlRDLLPvppavaeystglrMGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEVMtahvpPYKQPL--- 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 225 dgtekeiivDTDEGPREGVTAESLSKLRPAFD---GTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGV 301
Cdd:PRK08963 231 ---------EEDNNIRGDSTLEDYAKLRPAFDrkhGTVTAANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAI 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 302 PP-EIMGVGPAYAIPEVLKRTGLTVEDIDVFEINEAFAAQCL----------YSAEQVN-------VPEEKLNINGGAIA 363
Cdd:PRK08963 302 DVwQDMLLGPAYATPLALERAGLTLADLTLIDMHEAFAAQTLanlqmfaserFAREKLGrsqaigeVDMSKFNVLGGSIA 381
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 255722703 364 LGHPLGETGARQYATIIPLLKP--GQIGLTSMCIGSGMGSASILVRE 408
Cdd:PRK08963 382 YGHPFAATGARMITQTLHELRRrgGGLGLTTACAAGGLGAAMVLEVE 428
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
29-407 |
4.85e-66 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 214.96 E-value: 4.85e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 29 IVAAYRTAIGKGfKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLN---QAAGATehRGACLAAGIPYTAAF 105
Cdd:PRK07801 6 IVDAVRTPVGKR-KGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTigpQAGNIA--RTSWLAAGLPEEVPG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 106 IAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMST-------------NYRNPKVAPKIDEHLADDEQmekclIPM 172
Cdd:PRK07801 83 VTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQipissamtageqlGFTSPFAESKGWLHRYGDQE-----VSQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 173 GITNENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRSiirnsdgtekeiiVDTDEGPREgVTAESLSKLR 252
Cdd:PRK07801 158 FRGAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPVGG-------------VTVDEGPRE-TSLEKMAGLK 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 253 PAFDG-TTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVF 331
Cdd:PRK07801 224 PLVEGgRLTAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYALEKTGLSIDDIDVV 303
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 255722703 332 EINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLKP--GQIGLTSMCIGSGMGSASILVR 407
Cdd:PRK07801 304 EINEAFAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERtgGRYGLQTMCEGGGTANVTIIER 381
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
29-407 |
1.59e-62 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 206.12 E-value: 1.59e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 29 IVAAYRTAIG-KGfkGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATE-HRGACLAAGIPYTAAFI 106
Cdd:PRK06504 6 IVAAARTAGGrKG--GRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVGEQATNvARNAVLASKLPESVPGT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 107 AVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMS-------------TNYRNPKvAPKIDEHLADDE--QMekclip 171
Cdd:PRK06504 84 SIDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTrvpmgspstlpakNGLGHYK-SPGMEERYPGIQfsQF------ 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 172 MGItnENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRsiIRNSDGTEKeiIVDTDEGPREGVTAESLSKL 251
Cdd:PRK06504 157 TGA--EMMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLE--ITRADGSGE--MHTVDEGIRFDATLEGIAGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 252 RP-AFDGTTTAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDV 330
Cdd:PRK06504 231 KLiAEGGRLTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATERALKKAGMKIDDIDL 310
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 255722703 331 FEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLLKP--GQIGLTSMCIGSGMGSASILVR 407
Cdd:PRK06504 311 YEVNEAFASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQrgKRYGLQTMCEGGGMANVTIVER 389
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
26-407 |
9.86e-62 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 205.01 E-value: 9.86e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRT--AIGKGFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAA-GATEHRGACLAAGIPYT 102
Cdd:PRK06025 3 EAYIIDAVRTprGIGKVGKGALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGKqGGDLGRMAALDAGYDIK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 103 AAFIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMS--TNYRNPKVAPKIDEHLADDEQME-KCLIPM---GITN 176
Cdd:PRK06025 83 ASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSytAAMAAEDMAAGKPPLGMGSGNLRlRALHPQshqGVCG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 177 ENVASQFNISRERQDEFAAKSYNKAAKAVASGAFKQEILPIRsiirNSDGTekeIIVDTDEGPREGVTAESLSKLRPAFD 256
Cdd:PRK06025 163 DAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVPVY----RDDGS---VALDHEEFPRPQTTAEGLAALKPAFT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 257 ----------GTT------------------TAGNASQVSDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPPEIMGV 308
Cdd:PRK06025 236 aiadyplddkGTTyrglinqkypdleikhvhHAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTLMLN 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 309 GPAYAIPEVLKRTGLTVEDIDVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGHPLGETGARQYATIIPLL--KPG 386
Cdd:PRK06025 316 APVPAAKKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELerRGL 395
|
410 420
....*....|....*....|.
gi 255722703 387 QIGLTSMCIGSGMGSASILVR 407
Cdd:PRK06025 396 KRGLVTMCAAGGMAPAIIIER 416
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
287-407 |
1.51e-60 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 192.09 E-value: 1.51e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 287 YPIVGKYVLCSTAGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEINEAFAAQCLYSAEQVNVPEEKLNINGGAIALGH 366
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 255722703 367 PLGETGARQYATIIPLLKP--GQIGLTSMCIGSGMGSASILVR 407
Cdd:pfam02803 81 PLGASGARILVTLLHELKRrgGKYGLASLCIGGGQGVAMIIER 123
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
74-407 |
5.79e-59 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 197.82 E-value: 5.79e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 74 DVAMGNVLNQAAGATEHRGACLAAGI-PYTAAFiAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMStnyrnpkva 152
Cdd:PRK09268 55 EVVAGAVLKHSRDFNLTRECVLGSALsPYTPAY-DLQQACGTGLEAAILVANKIALGQIDSGIAGGVDTTS--------- 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 153 pkiDEHLADDEQMEKCL---------------------------IP----------MGITNENVASQFNISRERQDEFAA 195
Cdd:PRK09268 125 ---DAPIAVNEGLRKILlelnrakttgdrlkalgklrpkhlapeIPrngeprtglsMGEHAAITAKEWGISREAQDELAA 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 196 KSYNKAAKAVASGAFKQEILPIRSIIRnsdgtekeiivdtDEGPREGVTAESLSKLRPAFD----GTTTAGNASQVSDGA 271
Cdd:PRK09268 202 ASHQNLAAAYDRGFFDDLITPFLGLTR-------------DNNLRPDSSLEKLAKLKPVFGkggrATMTAGNSTPLTDGA 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 272 AAVLLMKRSLAEAKGYPIVGKYVLCSTAGVP----PEIMGVGPAYAIPEVLKRTGLTVEDIDVFEINEAFAAQCL----- 342
Cdd:PRK09268 269 SVVLLASEEWAAEHGLPVLAYLVDAETAAVDfvhgKEGLLMAPAYAVPRLLARNGLTLQDFDFYEIHEAFASQVLatlka 348
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 255722703 343 -----YSAEQVNVPE-------EKLNINGGAIALGHPLGETGARQYATIIPLL--KPGQIGLTSMCIGSGMGSASILVR 407
Cdd:PRK09268 349 wedeeYCRERLGLDAplgsidrSKLNVNGSSLAAGHPFAATGGRIVATLAKLLaeKGSGRGLISICAAGGQGVTAILER 427
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
30-402 |
1.77e-48 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 169.60 E-value: 1.77e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 30 VAAYRTAIGK--GFKGSFRSVQSEFILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAFIA 107
Cdd:cd00826 1 AGAAMTAFGKfgGENGADANDLAHEAGAKAIAAALEPAGVAAGAVEEACLGQVLGAGEGQNCAQQAAMHAGGLQEAPAIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 108 VNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTNYRNPKVAPKIDehladdeqmekclipmgitnenVASQFNISR 187
Cdd:cd00826 81 MNNLCGSGLRALALAMQLIAGGDANCILAGGFEKMETSAENNAKEKHID----------------------VLINKYGMR 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 188 ERQDEFAAKSYNKAAKAVASGAFKQEILPIrsIIRNSDGtekEIIVDTDEGPREG--VTAESLSKLRPAFD--GTTTAGN 263
Cdd:cd00826 139 ACPDAFALAGQAGAEAAEKDGRFKDEFAKF--GVKGRKG---DIHSDADEYIQFGdeASLDEIAKLRPAFDkeDFLTAGN 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 264 ASQVSDGAAAVLLMKRSLAE-------AKGYPIVGKYVLCSTAGVPPE----IMGVGPAYAIPEVLKRTGLTVEDIDVFE 332
Cdd:cd00826 214 ACGLNDGAAAAILMSEAEAQkhglqskAREIQALEMITDMASTFEDKKvikmVGGDGPIEAARKALEKAGLGIGDLDLIE 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 333 INEAFAAQCLYSAEQVNV-PEEK-----------------LNINGGAIALGHPLGETGARQYATIIPLLK--------PG 386
Cdd:cd00826 294 AHDAFAANACATNEALGLcPEGQggalvdrgdntyggksiINPNGGAIAIGHPIGASGAAICAELCFELKgeagkrqgAG 373
|
410
....*....|....*.
gi 255722703 387 QiGLTSMCIGSGMGSA 402
Cdd:cd00826 374 A-GLALLCIGGGGGAA 388
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
53-375 |
5.83e-14 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 72.68 E-value: 5.83e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 53 ILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLAAGIPYTAAfIAVNRFCSSGLMAISDIANKIKTGEIE 132
Cdd:cd00829 19 LAAEAARAALDDAGLEPADIDAVVVGNAAGGRFQSFPGALIAEYLGLLGKPA-TRVEAAGASGSAAVRAAAAAIASGLAD 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 133 CGLAGGVESMSTnyrnpkvAPKIDEHLADDEQMEK--CLIPMGITNENVA--------SQFNISRERQDEFAAKSYNKAA 202
Cdd:cd00829 98 VVLVVGAEKMSD-------VPTGDEAGGRASDLEWegPEPPGGLTPPALYalaarrymHRYGTTREDLAKVAVKNHRNAA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 203 KAvasgafkqeilPiRSIIRnsdgteKEIIVDTDEGPRegVTAESLSKLrpafdgtttagNASQVSDGAAAVLLMkrSLA 282
Cdd:cd00829 171 RN-----------P-YAQFR------KPITVEDVLNSR--MIADPLRLL-----------DCCPVSDGAAAVVLA--SEE 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 283 EAKGYP-----IVGKYVLCSTAGVPPEIMGVGP---AYAIPEVLKRTGLTVEDIDVFEINEAFAAQCL------------ 342
Cdd:cd00829 218 RARELTdrpvwILGVGAASDTPSLSERDDFLSLdaaRLAARRAYKMAGITPDDIDVAELYDCFTIAELlaledlgfcekg 297
|
330 340 350
....*....|....*....|....*....|....*....
gi 255722703 343 ----YSAEQVNVPEEKL--NINGGAIALGHPLGETGARQ 375
Cdd:cd00829 298 eggkLVREGDTAIGGDLpvNTSGGLLSKGHPLGATGLAQ 336
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
261-405 |
9.41e-13 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 67.85 E-value: 9.41e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 261 AGNASQVSDGAAAVLLMkrSLAEAKGYPIVGKYVLCST------AGVPPEIMGVGPAYAIPEVLKRTGLTVEDIDVFEIN 334
Cdd:cd00327 94 GSEEFVFGDGAAAAVVE--SEEHALRRGAHPQAEIVSTaatfdgASMVPAVSGEGLARAARKALEGAGLTPSDIDYVEAH 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 335 EAFAAQCLYSAEQVNVPEEK---LNINGGAIALGHPLGETGARQYAT---------IIPLLKPGQIGLTSMCIGSGMGSA 402
Cdd:cd00327 172 GTGTPIGDAVELALGLDPDGvrsPAVSATLIMTGHPLGAAGLAILDElllmlehefIPPTPREPRTVLLLGFGLGGTNAA 251
|
...
gi 255722703 403 SIL 405
Cdd:cd00327 252 VVL 254
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
26-384 |
1.32e-10 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 62.61 E-value: 1.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 26 DVVIVAAYRTAIGKGFKGSFRSvqsefILAEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLA--AGIPYTA 103
Cdd:PRK06064 3 DVAIIGVGQTKFGELWDVSLRD-----LAVEAGLEALEDAGIDGKDIDAMYVGNMSAGLFVSQEHIAALIAdyAGLAPIP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 104 AfIAVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMsTNYRNPKVAPKIDEhlADDEQMEKClipMGIT----NENV 179
Cdd:PRK06064 78 A-TRVEAACASGGAALRQAYLAVASGEADVVLAAGVEKM-TDVPTPDATEAIAR--AGDYEWEEF---FGATfpglYALI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 180 AS----QFNISRERQDEFAAKSYNKAAKavasgafkqeilpirsiirNSDGT-EKEIIVDTDEGPRegVTAESLsKLrpa 254
Cdd:PRK06064 151 ARrymhKYGTTEEDLALVAVKNHYNGSK-------------------NPYAQfQKEITVEQVLNSP--PVADPL-KL--- 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 255 FDgtttagnASQVSDGAAAVLLMkrSLAEAKGYPIVGKYVLCSTAGVP-------PEIMGVGPA-YAIPEVLKRTGLTVE 326
Cdd:PRK06064 206 LD-------CSPITDGAAAVILA--SEEKAKEYTDTPVWIKASGQASDtialhdrKDFTTLDAAvVAAEKAYKMAGIEPK 276
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 255722703 327 DIDVFEINEAF--AAQCLYSA-------EQVNVPEEK---------LNINGGAIALGHPLGETGARQYATIIPLLK 384
Cdd:PRK06064 277 DIDVAEVHDCFtiAEILAYEDlgfakkgEGGKLAREGqtyiggdipVNPSGGLKAKGHPVGATGVSQAVEIVWQLR 352
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
25-374 |
1.83e-08 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 55.85 E-value: 1.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 25 DDVVIVAAYR-------TAIGKGFKGSFRsvqsefilaEFLKEFIKKTKVDPSLIEDVAMGNVLNQAAGATEHRGACLA- 96
Cdd:PRK06289 3 DDVWVLGGYQsdfarnwTKEGRDFADLTR---------EVVDGTLAAAGVDADDIEVVHVGNFFGELFAGQGHLGAMPAt 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 97 -----AGIP---YTAAfiavnrfCSSGLMAISDIANKIKTGEIECGLAGGVESMSTnyrnpkV-APKIDEHL-----ADD 162
Cdd:PRK06289 74 vhpalWGVPasrHEAA-------CASGSVATLAAMADLRAGRYDVALVVGVELMKT------VpGDVAAEHLgaaawTGH 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 163 E-QMEKCLIP--MGITNENVASQFNISRERQDEFAAKSYNKAAK---AVASGAFkqeiLPirsiirnsdgteKEIIVDTD 236
Cdd:PRK06289 141 EgQDARFPWPsmFARVADEYDRRYGLDEEHLRAIAEINFANARRnpnAQTRGWA----FP------------DEATNDDD 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 237 EgpregvtaeslskLRPAFDGTTTAGNASQVSDGAAAVLLM----------KRSLAEAKGY-----PIVGKYVLCSTAGV 301
Cdd:PRK06289 205 A-------------TNPVVEGRLRRQDCSQVTDGGAGVVLAsdaylrdyadARPIPRIKGWghrtaPLGLEQKLDRSAGD 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 302 P---PEIMGvgpayAIPEVLKRTGLTVEDIDVFEINEAFAAQCLYSAEQVNV--PEE--------------KLNIN--GG 360
Cdd:PRK06289 272 PyvlPHVRQ-----AVLDAYRRAGVGLDDLDGFEVHDCFTPSEYLAIDHIGLtgPGEswkaiengeiaiggRLPINpsGG 346
|
410
....*....|....
gi 255722703 361 AIALGHPLGETGAR 374
Cdd:PRK06289 347 LIGGGHPVGASGVR 360
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
27-393 |
5.42e-06 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 48.35 E-value: 5.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 27 VVIVAAYRTA-IGKGFK----------GSFRSVQSEFILAEFLKEFIKKTKVD--PSLIEDVAMGNVLNQAAGATEHRG- 92
Cdd:PTZ00455 14 VFVVGGHITPfVGKGSPlfidkkhpdfGKKENKTLEELLATAIQGTLENTGLDgkAALVDKVVVGNFLGELFSSQGHLGp 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 93 -ACLAAGIP-YTAAFI-----AVNRFCSSGLMAISDIANKIKTGEIECGLAGGVESMSTnyrnpkVAPKID-EHLADdeq 164
Cdd:PTZ00455 94 aAVGSLGQSgASNALLykpamRVEGACASGGLAVQSAWEALLAGTSDIALVVGVEVQTT------VSARVGgDYLAR--- 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 165 mekclipmgitnenvASQFNisRERQ-DEFAAKS-YNKAAKAVA-SGAFKQEILPIRSIIRNSDGTEKEII-VDTDEGPR 240
Cdd:PTZ00455 165 ---------------AADYR--RQRKlDDFTFPClFAKRMKYIQeHGHFTMEDTARVAAKAYANGNKNPLAhMHTRKLSL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 241 EGVTAESLSKlrPAFDGTTT------AGNASQVSDGAAAVLLM------KRSLAEAKGYPIVGKYVLCSTAGV---PPEI 305
Cdd:PTZ00455 228 EFCTGASDKN--PKFLGNETykpflrMTDCSQVSDGGAGLVLAseeglqKMGLSPNDSRLVEIKSLACASGNLyedPPDA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 306 MGVGPAY-AIPEVLKRTGLTVEDIDVFEINEAFAAQCLYSAEQVNVPEE------------------KLNINGGAIALGH 366
Cdd:PTZ00455 306 TRMFTSRaAAQKALSMAGVKPSDLQVAEVHDCFTIAELLMYEALGIAEYghakdlirngatalegriPVNTGGGLLSFGH 385
|
410 420
....*....|....*....|....*..
gi 255722703 367 PLGETGARQYATIIPLLKpGQIGLTSM 393
Cdd:PTZ00455 386 PVGATGVKQIMEVYRQMK-GQCGEYQM 411
|
|
| elong_cond_enzymes |
cd00828 |
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
244-376 |
6.20e-04 |
|
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP) thioesters as primer substrates, as well as the nature of their active site residues.
Pssm-ID: 238424 [Multi-domain] Cd Length: 407 Bit Score: 41.66 E-value: 6.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 244 TAESLSKLRPAFDGTTTAGNASQV--SDGAAAVLLMKRSLAEAKGYPIVGKYVLCSTAGVPP----EIMGVGPAYAIPEV 317
Cdd:cd00828 204 GALSTAEEEPEEMSRPFDETRDGFveAEGAGVLVLERAELALARGAPIYGRVAGTASTTDGAgrsvPAGGKGIARAIRTA 283
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 255722703 318 LKRTGLTVEDIDVfeINEAFAAQclysaeQVNVPEEKLNINGGAIALGHPLGETGARQY 376
Cdd:cd00828 284 LAKAGLSLDDLDV--ISAHGTST------PANDVAESRAIAEVAGALGAPLPVTAQKAL 334
|
|
| KAS_III |
cd00830 |
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ... |
313-406 |
7.25e-03 |
|
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.
Pssm-ID: 238426 [Multi-domain] Cd Length: 320 Bit Score: 38.29 E-value: 7.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 255722703 313 AIPEVLKRTGLTVEDIDVF-------EINEAFaaqclysAEQVNVPEEKLNINggaialGHPLGETGArqyATiIPL--- 382
Cdd:cd00830 228 SIEEALEKAGLTPDDIDWFvphqanlRIIEAV-------AKRLGLPEEKVVVN------LDRYGNTSA---AS-IPLald 290
|
90 100 110
....*....|....*....|....*....|..
gi 255722703 383 -------LKPGQIGLtsMC-IGSGMGSASILV 406
Cdd:cd00830 291 eaieegkLKKGDLVL--LLgFGAGLTWGAALL 320
|
|
| |
