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Conserved domains on  [gi|25057954|ref|NP_740164|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Arcos sp. KU 149]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.56e-66

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 199.98  E-value: 2.56e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954    1 MAYIMFILLVVLVVGLAAVASNPSPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954   81 TWGSLPVLGLMCGYLVGVLGVVSLFWGGWYSSSWFSVEEFSELSVVRGDVGGVALMYSNGAGMLVVGGGVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 25057954  161 LTRGVSRGALRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.56e-66

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 199.98  E-value: 2.56e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954    1 MAYIMFILLVVLVVGLAAVASNPSPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954   81 TWGSLPVLGLMCGYLVGVLGVVSLFWGGWYSSSWFSVEEFSELSVVRGDVGGVALMYSNGAGMLVVGGGVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 25057954  161 LTRGVSRGALRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
21-114 1.76e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.28  E-value: 1.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954    21 SNPSPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAAL-AAEPYPETWGSLPVLGLMCGYLVGVL 99
Cdd:pfam00499   5 TSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGLLLLA 84

                          90
                  ....*....|....*
gi 25057954   100 GVVSLFWGGWYSSSW 114
Cdd:pfam00499  85 LLLLVLLSASLTPAA 99
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 2.56e-66

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 199.98  E-value: 2.56e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954    1 MAYIMFILLVVLVVGLAAVASNPSPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954   81 TWGSLPVLGLMCGYLVGVLGVVSLFWGGWYSSSWFSVEEFSELSVVRGDVGGVALMYSNGAGMLVVGGGVLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 25057954  161 LTRGVSRGALRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 2.93e-41

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 136.52  E-value: 2.93e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954    1 MAYIMFILLVVLVVGLAAVASNPSPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954   81 TWGSLPVLGLMCGYLVgVLGVVSLFWGGWYSSSWFSVEEFSELSVVRGDVGGVALMYSNGAGMLVVGGGVLLLTLFVVLE 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLL-LLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                        170
                 ....*....|...
gi 25057954  161 LTRGVSRGALRAV 173
Cdd:MTH00065 160 VTRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 3.62e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 107.91  E-value: 3.62e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954    1 MAYIMFILLVVLVVGLAAVASNPSPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954   81 TWGSLPVLGLMCGYLVGVLgVVSLFWGGWYSSSWFSVE--EFSELSVVRGDVGGVALMYSNGAGMLVVGGGVLLLTLFVV 158
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVV-VVGVVVGGLWGMEGVGVVtvDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVV 159

                        170
                 ....*....|....*
gi 25057954  159 LELTRGVSRGALRAV 173
Cdd:MTH00115 160 LELVRGLSRGALRAF 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 1.35e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 93.51  E-value: 1.35e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954    1 MAYIMFILLVVLVVGLAAVASNPSPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954   81 TWGSLPVLGLMCGYLVGVLGVVSLFWGGWYSSSWFSVEEFSELSvvrgdVGGVALMYSNGAGMLVVGGGVLLLTLFVVLE 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLD-----LSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 25057954  161 LTRGVSRGALRAV 173
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-138 2.21e-24

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 93.33  E-value: 2.21e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954    1 MAYIMFILLVVLVVGLAAVASNPSPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25057954   81 TWGS-LPVLGLMCGYLVGVLGVVSLFWGGWYSSSWFSVE--------EFSELSVVRGDVGGVALMYS 138
Cdd:MTH00109  82 TWVSnKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNglgdwviyDTGGSGFFSEDAMGVAALYS 148
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 24-172 9.19e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 65.31  E-value: 9.19e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954   24 SPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPETWGSLPVLGLMcgylvgvlgVVS 103
Cdd:MTH00045  22 SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSVSNLGEVLVLS---------LLL 92

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25057954  104 LFWGGWYSSSWFSVEEFSELSVVRGDVGGVALMYSNGAGMLVVGGGVLLLTLFVVLELTRGVSRGALRA 172
Cdd:MTH00045  93 SLWVFISFDNFLELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
21-114 1.76e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 53.28  E-value: 1.76e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954    21 SNPSPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAAL-AAEPYPETWGSLPVLGLMCGYLVGVL 99
Cdd:pfam00499   5 TSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGLLLLA 84

                          90
                  ....*....|....*
gi 25057954   100 GVVSLFWGGWYSSSW 114
Cdd:pfam00499  85 LLLLVLLSASLTPAA 99
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 32-104 6.24e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 35.37  E-value: 6.24e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 25057954   32 LVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPETWGSLPVLGLMCGYLVGVLGVVSL 104
Cdd:MTH00212  30 LLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEHLFFKKYFKGFGMILISLNLYLLLMTL 102
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 24-125 6.62e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 35.63  E-value: 6.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25057954   24 SPYYAALGLVVVAGVSCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPETWGSLPVLGLMCGYLVGVLGVVS 103
Cdd:MTH00152  22 QPLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSPNPLFGSNFKFVFFSLTLFGFLGLFFFFL 101

                         90       100
                 ....*....|....*....|..
gi 25057954  104 LFWGGWYSSSWFSVEEFSELSV 125
Cdd:MTH00152 102 YLYSSGGLSLSSLFDGSSGSLS 123
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 49-74 9.48e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 34.78  E-value: 9.48e-03
                         10        20
                 ....*....|....*....|....*.
gi 25057954   49 SFLSLVLFLIYLGGMLVVFAYSAALA 74
Cdd:MTH00166  46 FWFSYILFLIFLGGMLVLFIYITSLA 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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