CSC1 family protein may act as an osmosensitive calcium-permeable cation channel; similar to Saccharomyces cerevisiae calcium permeable stress-gated cation channel 1, sporulation-specific protein 75, phosphate metabolism protein 7 and uncharacterized protein RSN1
Calcium-dependent channel, 7TM region, putative phosphate; RSN1_7TM is the seven transmembrane ...
387-659
2.85e-114
Calcium-dependent channel, 7TM region, putative phosphate; RSN1_7TM is the seven transmembrane domain region of putative phosphate transporter. The family is the 7TM region of osmosensitive calcium-permeable cation channels.
Pssm-ID: 460661 Cd Length: 273 Bit Score: 351.44 E-value: 2.85e-114
Calcium-dependent channel, 7TM region, putative phosphate; RSN1_7TM is the seven transmembrane ...
387-659
2.85e-114
Calcium-dependent channel, 7TM region, putative phosphate; RSN1_7TM is the seven transmembrane domain region of putative phosphate transporter. The family is the 7TM region of osmosensitive calcium-permeable cation channels.
Pssm-ID: 460661 Cd Length: 273 Bit Score: 351.44 E-value: 2.85e-114
Late exocytosis, associated with Golgi transport; This family represents the first three ...
22-171
1.52e-48
Late exocytosis, associated with Golgi transport; This family represents the first three transmembrane regions of 11-TM proteins involved in vesicle transport. In S. cerevisiae these proteins are members of the yeast facilitator superfamily and are integral membrane proteins localized to the cell periphery, in particular to the bud-neck region. The distribution is consistent with a role in late exocytosis which is in agreement with the proteins' ability to substitute for the function of Sro7p, required for the sorting of the protein Enap1 into Golgi-derived vesicles destined for the cell surface.
Pssm-ID: 433613 Cd Length: 158 Bit Score: 169.29 E-value: 1.52e-48
Cytosolic domain of 10TM putative phosphate transporter; PHM7_cyt is the predicted cytosolic ...
194-376
4.99e-35
Cytosolic domain of 10TM putative phosphate transporter; PHM7_cyt is the predicted cytosolic domain of integral membrane proteins, such as yeast PHM7 and TM63A_HUMAN TRANSMEMBRANE PROTEIN 63A, SwissProt:O94886. This domain usually precedes the 7TM region, pfam02714, and follows a RSN1_TM, pfam13967. Fold recognition programs consistently and with high significance predict this domain to be distantly homologous to RNA binding proteins from the RRM clan.
Pssm-ID: 464272 Cd Length: 164 Bit Score: 130.91 E-value: 4.99e-35
Extracellular tail, of 10TM putative phosphate transporter; This PHM7_ext family is found in ...
827-912
1.88e-27
Extracellular tail, of 10TM putative phosphate transporter; This PHM7_ext family is found in plants and fungi. It represents the C-terminal extracellular domain of the putative phosphate transporter, PHM7. The three N-terminal TMS are found in family RSN1_TM, pfam02714; the cytoplssmic domain is pfam14703, and the remaining 7TM region is in pfam02714.
Pssm-ID: 432676 Cd Length: 84 Bit Score: 106.46 E-value: 1.88e-27
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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