NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|242005915|ref|XP_002423805|]
View 

WD-repeat protein, putative [Pediculus humanus corporis]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
86-415 5.23e-105

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 316.47  E-value: 5.23e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  86 LTLKTHILPVTNVAFDKNGQRCITGSYDRTCKVWNVENGKEILTLEGHINAVYSVSFNmPTCNRILTGSFDRTAKLWCSQ 165
Cdd:COG2319   72 ATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFS-PDGKTLASGSADGTVRLWDLA 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 166 TGNCLRTLWGHTAEVVTAKF--DGKqqLIATGSMDRTAKLFDVMTGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTV 243
Cdd:COG2319  151 TGKLLRTLTGHSGAVTSVAFspDGK--LLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 244 SVWDTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGHDSDVLDIAFDCYGKRLATAST 323
Cdd:COG2319  229 RLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSD 308

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 324 DCTARVWDVSSNfKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWNPDTGCCIQVLQGHSDEVFSGVYSYNGDVL 403
Cdd:COG2319  309 DGTVRLWDLATG-KLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTL 387

                        330
                 ....*....|..
gi 242005915 404 MTASKDNTCQIW 415
Cdd:COG2319  388 ASGSADGTVRLW 399
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
86-415 5.23e-105

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 316.47  E-value: 5.23e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  86 LTLKTHILPVTNVAFDKNGQRCITGSYDRTCKVWNVENGKEILTLEGHINAVYSVSFNmPTCNRILTGSFDRTAKLWCSQ 165
Cdd:COG2319   72 ATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFS-PDGKTLASGSADGTVRLWDLA 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 166 TGNCLRTLWGHTAEVVTAKF--DGKqqLIATGSMDRTAKLFDVMTGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTV 243
Cdd:COG2319  151 TGKLLRTLTGHSGAVTSVAFspDGK--LLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 244 SVWDTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGHDSDVLDIAFDCYGKRLATAST 323
Cdd:COG2319  229 RLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSD 308

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 324 DCTARVWDVSSNfKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWNPDTGCCIQVLQGHSDEVFSGVYSYNGDVL 403
Cdd:COG2319  309 DGTVRLWDLATG-KLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTL 387

                        330
                 ....*....|..
gi 242005915 404 MTASKDNTCQIW 415
Cdd:COG2319  388 ASGSADGTVRLW 399
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 87-374 3.41e-83

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 256.49  E-value: 3.41e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  87 TLKTHILPVTNVAFDKNGQRCITGSYDRTCKVWNVENGKEILTLEGHINAVYSVSFnMPTCNRILTGSFDRTAKLWCSQT 166
Cdd:cd00200    4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAA-SADGTYLASGSSDKTIRLWDLET 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 167 GNCLRTLWGHTAEVVTAKFDGKQQLIATGSMDRTAKLFDVMTGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVW 246
Cdd:cd00200   83 GECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLW 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 247 DTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGHDSDVLDIAFDCYGKRLATASTDCT 326
Cdd:cd00200  163 DLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGT 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 242005915 327 ARVWDVSSnFKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWN 374
Cdd:cd00200  243 IRVWDLRT-GECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 95-366 5.21e-13

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 70.89  E-value: 5.21e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  95 VTNVAFDKNGQRCITGSYDRTCKVWN----VENGKEI----LTLEGHiNAVYSVSFNMPTCNRILTGSFDRTAKLWCSQT 166
Cdd:PLN00181 486 VCAIGFDRDGEFFATAGVNKKIKIFEcesiIKDGRDIhypvVELASR-SKLSGICWNSYIKSQVASSNFEGVVQVWDVAR 564

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 167 GNCLRTLWGHTAEVVTAKFDGKQ-QLIATGSMDRTAKLFDVMTGQETGTLRGhTAEVTTVDF-DKTGNRLITSSFDSTVS 244
Cdd:PLN00181 565 SQLVTEMKEHEKRVWSIDYSSADpTLLASGSDDGSVKLWSINQGVSIGTIKT-KANICCVQFpSESGRSLAFGSADHKVY 643

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 245 VWDTRTNK-RVGVLIGHRNEISNALFnFDCDLIASSSVDKTAKIWDPRMF------TCLVTITGHDSDVLDIAFDCYGKR 317
Cdd:PLN00181 644 YYDLRNPKlPLCTMIGHSKTVSYVRF-VDSSTLVSSSTDNTLKLWDLSMSisgineTPLHSFMGHTNVKNFVGLSVSDGY 722

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 242005915 318 LATASTDCTARVWD-------VSSNFKLISTMEGHK-DEVSQ----VCFNpGGTQVLTASN 366
Cdd:PLN00181 723 IATGSETNEVFVYHkafpmpvLSYKFKTIDPVSGLEvDDASQfissVCWR-GQSSTLVAAN 782
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 208-247 2.47e-08

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 49.62  E-value: 2.47e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 242005915   208 TGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVWD 247
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
209-247 1.51e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 47.34  E-value: 1.51e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 242005915  209 GQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVWD 247
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
86-415 5.23e-105

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 316.47  E-value: 5.23e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  86 LTLKTHILPVTNVAFDKNGQRCITGSYDRTCKVWNVENGKEILTLEGHINAVYSVSFNmPTCNRILTGSFDRTAKLWCSQ 165
Cdd:COG2319   72 ATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFS-PDGKTLASGSADGTVRLWDLA 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 166 TGNCLRTLWGHTAEVVTAKF--DGKqqLIATGSMDRTAKLFDVMTGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTV 243
Cdd:COG2319  151 TGKLLRTLTGHSGAVTSVAFspDGK--LLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTV 228

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 244 SVWDTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGHDSDVLDIAFDCYGKRLATAST 323
Cdd:COG2319  229 RLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSD 308

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 324 DCTARVWDVSSNfKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWNPDTGCCIQVLQGHSDEVFSGVYSYNGDVL 403
Cdd:COG2319  309 DGTVRLWDLATG-KLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTL 387

                        330
                 ....*....|..
gi 242005915 404 MTASKDNTCQIW 415
Cdd:COG2319  388 ASGSADGTVRLW 399
WD40 COG2319
WD40 repeat [General function prediction only];
87-377 1.83e-95

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 291.81  E-value: 1.83e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  87 TLKTHILPVTNVAFDKNGQRCITGSYDRTCKVWNVENGKEILTLEGHINAVYSVSFNmPTCNRILTGSFDRTAKLWCSQT 166
Cdd:COG2319  115 TLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFS-PDGKLLASGSDDGTVRLWDLAT 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 167 GNCLRTLWGHTAEVVTAKFDGKQQLIATGSMDRTAKLFDVMTGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVW 246
Cdd:COG2319  194 GKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLW 273

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 247 DTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGHDSDVLDIAFDCYGKRLATASTDCT 326
Cdd:COG2319  274 DLATGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGT 353

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 242005915 327 ARVWDVSSNfKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWNPDT 377
Cdd:COG2319  354 VRLWDLATG-ELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
WD40 COG2319
WD40 repeat [General function prediction only];
86-415 3.24e-93

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 286.04  E-value: 3.24e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  86 LTLKTHILPVTNVAFDKNGQRCITGSYDRTCKVWNVENGKEILTLEGHINAVYSVSFnMPTCNRILTGSFDRTAKLWCSQ 165
Cdd:COG2319   30 LLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAF-SPDGRLLASASADGTVRLWDLA 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 166 TGNCLRTLWGHTAEVVTAKF--DGkqQLIATGSMDRTAKLFDVMTGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTV 243
Cdd:COG2319  109 TGLLLRTLTGHTGAVRSVAFspDG--KTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTV 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 244 SVWDTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGHDSDVLDIAF--DcyGKRLATA 321
Cdd:COG2319  187 RLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFspD--GRLLASG 264

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 322 STDCTARVWDVSSNfKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWNPDTGCCIQVLQGHSDEVFSGVYSYNGD 401
Cdd:COG2319  265 SADGTVRLWDLATG-ELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGK 343

                        330
                 ....*....|....
gi 242005915 402 VLMTASKDNTCQIW 415
Cdd:COG2319  344 TLASGSDDGTVRLW 357
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 87-374 3.41e-83

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 256.49  E-value: 3.41e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  87 TLKTHILPVTNVAFDKNGQRCITGSYDRTCKVWNVENGKEILTLEGHINAVYSVSFnMPTCNRILTGSFDRTAKLWCSQT 166
Cdd:cd00200    4 TLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAA-SADGTYLASGSSDKTIRLWDLET 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 167 GNCLRTLWGHTAEVVTAKFDGKQQLIATGSMDRTAKLFDVMTGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVW 246
Cdd:cd00200   83 GECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLW 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 247 DTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGHDSDVLDIAFDCYGKRLATASTDCT 326
Cdd:cd00200  163 DLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGT 242

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 242005915 327 ARVWDVSSnFKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWN 374
Cdd:cd00200  243 IRVWDLRT-GECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 126-416 8.36e-83

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 255.34  E-value: 8.36e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 126 EILTLEGHINAVYSVSFNmPTCNRILTGSFDRTAKLWCSQTGNCLRTLWGHTAEVVTAKFDGKQQLIATGSMDRTAKLFD 205
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFS-PDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 206 VMTGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVWDTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTA 285
Cdd:cd00200   80 LETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 286 KIWDPRMFTCLVTITGHDSDVLDIAFDCYGKRLATASTDCTARVWDVSSnFKLISTMEGHKDEVSQVCFNPGGTQVLTAS 365
Cdd:cd00200  160 KLWDLRTGKCVATLTGHTGEVNSVAFSPDGEKLLSSSSDGTIKLWDLST-GKCLGTLRGHENGVNSVAFSPDGYLLASGS 238

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 242005915 366 NDKTARIWNPDTGCCIQVLQGHSDEVFSGVYSYNGDVLMTASKDNTCQIWK 416
Cdd:cd00200  239 EDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
149-415 4.72e-65

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 213.62  E-value: 4.72e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 149 RILTGSFDRTAKLWCSQTGNCLRTLWGHTAEVVTAKFDGKQQLIATGSMDRTAKLFDVMTGQETGTLRGHTAEVTTVDFD 228
Cdd:COG2319    8 ALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFS 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 229 KTGNRLITSSFDSTVSVWDTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGHDSDVLD 308
Cdd:COG2319   88 PDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLTGHSGAVTS 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 309 IAF--DcyGKRLATASTDCTARVWDVSSNfKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWNPDTGCCIQVLQG 386
Cdd:COG2319  168 VAFspD--GKLLASGSDDGTVRLWDLATG-KLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTG 244

                        250       260
                 ....*....|....*....|....*....
gi 242005915 387 HSDEVFSGVYSYNGDVLMTASKDNTCQIW 415
Cdd:COG2319  245 HSGSVRSVAFSPDGRLLASGSADGTVRLW 273
WD40 COG2319
WD40 repeat [General function prediction only];
185-415 1.37e-49

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 172.79  E-value: 1.37e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 185 FDGKQQLIATGSMDRTAKLFDVMTGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVWDTRTNKRVGVLIGHRNEI 264
Cdd:COG2319    2 LSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 265 SNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGHDSDVLDIAF--DcyGKRLATASTDCTARVWDVSSNfKLISTM 342
Cdd:COG2319   82 LSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFspD--GKTLASGSADGTVRLWDLATG-KLLRTL 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 242005915 343 EGHKDEVSQVCFNPGGTQVLTASNDKTARIWNPDTGCCIQVLQGHSDEVFSGVYSYNGDVLMTASKDNTCQIW 415
Cdd:COG2319  159 TGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLW 231
WD40 COG2319
WD40 repeat [General function prediction only];
226-415 2.64e-35

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 134.27  E-value: 2.64e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 226 DFDKTGNRLITSSFDSTVSVWDTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGHDSD 305
Cdd:COG2319    1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 306 VLDIAFDCYGKRLATASTDCTARVWDVSSNfKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWNPDTGCCIQVLQ 385
Cdd:COG2319   81 VLSVAFSPDGRLLASASADGTVRLWDLATG-LLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRTLT 159

                        170       180       190
                 ....*....|....*....|....*....|
gi 242005915 386 GHSDEVFSGVYSYNGDVLMTASKDNTCQIW 415
Cdd:COG2319  160 GHSGAVTSVAFSPDGKLLASGSDDGTVRLW 189
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 95-366 5.21e-13

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 70.89  E-value: 5.21e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  95 VTNVAFDKNGQRCITGSYDRTCKVWN----VENGKEI----LTLEGHiNAVYSVSFNMPTCNRILTGSFDRTAKLWCSQT 166
Cdd:PLN00181 486 VCAIGFDRDGEFFATAGVNKKIKIFEcesiIKDGRDIhypvVELASR-SKLSGICWNSYIKSQVASSNFEGVVQVWDVAR 564

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 167 GNCLRTLWGHTAEVVTAKFDGKQ-QLIATGSMDRTAKLFDVMTGQETGTLRGhTAEVTTVDF-DKTGNRLITSSFDSTVS 244
Cdd:PLN00181 565 SQLVTEMKEHEKRVWSIDYSSADpTLLASGSDDGSVKLWSINQGVSIGTIKT-KANICCVQFpSESGRSLAFGSADHKVY 643

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 245 VWDTRTNK-RVGVLIGHRNEISNALFnFDCDLIASSSVDKTAKIWDPRMF------TCLVTITGHDSDVLDIAFDCYGKR 317
Cdd:PLN00181 644 YYDLRNPKlPLCTMIGHSKTVSYVRF-VDSSTLVSSSTDNTLKLWDLSMSisgineTPLHSFMGHTNVKNFVGLSVSDGY 722

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 242005915 318 LATASTDCTARVWD-------VSSNFKLISTMEGHK-DEVSQ----VCFNpGGTQVLTASN 366
Cdd:PLN00181 723 IATGSETNEVFVYHkafpmpvLSYKFKTIDPVSGLEvDDASQfissVCWR-GQSSTLVAAN 782
PTZ00421 PTZ00421
coronin; Provisional
 301-414 4.08e-10

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 61.45  E-value: 4.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 301 GHDSDVLDIAFDCY-GKRLATASTDCTARVWDV------SSNFKLISTMEGHKDEVSQVCFNPGGTQVL-TASNDKTARI 372
Cdd:PTZ00421  73 GQEGPIIDVAFNPFdPQKLFTASEDGTIMGWGIpeegltQNISDPIVHLQGHTKKVGIVSFHPSAMNVLaSAGADMVVNV 152

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 242005915 373 WNPDTGCCIQVLQGHSDEVFSGVYSYNGDVLMTASKDNTCQI 414
Cdd:PTZ00421 153 WDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNI 194
PTZ00421 PTZ00421
coronin; Provisional
 215-304 2.21e-08

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 56.05  E-value: 2.21e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 215 LRGHTAEVTTVDFDKTGNRLITSS-FDSTVSVWDTRTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPRMF 293
Cdd:PTZ00421 121 LQGHTKKVGIVSFHPSAMNVLASAgADMVVNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDG 200

                         90
                 ....*....|.
gi 242005915 294 TCLVTITGHDS 304
Cdd:PTZ00421 201 TIVSSVEAHAS 211
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 180-374 2.24e-08

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 56.25  E-value: 2.24e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 180 VVTAKFDGKQQLIATGSMDRTAKLFDVMTGQETG--------TLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVWDTRTN 251
Cdd:PLN00181 486 VCAIGFDRDGEFFATAGVNKKIKIFECESIIKDGrdihypvvELASRSKLSGICWNSYIKSQVASSNFEGVVQVWDVARS 565

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 252 KRVGVLIGHRNEI-SNALFNFDCDLIASSSVDKTAKIWDPRMFTCLVTITGhDSDVLDIAFDC-YGKRLATASTDCTARV 329
Cdd:PLN00181 566 QLVTEMKEHEKRVwSIDYSSADPTLLASGSDDGSVKLWSINQGVSIGTIKT-KANICCVQFPSeSGRSLAFGSADHKVYY 644

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 242005915 330 WDVSSNFKLISTMEGHKDEVSQVCFNPGGTQVlTASNDKTARIWN 374
Cdd:PLN00181 645 YDLRNPKLPLCTMIGHSKTVSYVRFVDSSTLV-SSSTDNTLKLWD 688
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 208-247 2.47e-08

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 49.62  E-value: 2.47e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 242005915   208 TGQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVWD 247
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 335-374 3.48e-08

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 49.23  E-value: 3.48e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 242005915   335 NFKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWN 374
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 293-331 1.40e-07

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 47.31  E-value: 1.40e-07
                           10        20        30
                   ....*....|....*....|....*....|....*....
gi 242005915   293 FTCLVTITGHDSDVLDIAFDCYGKRLATASTDCTARVWD 331
Cdd:smart00320   2 GELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
209-247 1.51e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 47.34  E-value: 1.51e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 242005915  209 GQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVWD 247
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
336-374 2.27e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 46.95  E-value: 2.27e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 242005915  336 FKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWN 374
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
293-331 2.99e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 46.57  E-value: 2.99e-07
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 242005915  293 FTCLVTITGHDSDVLDIAFDCYGKRLATASTDCTARVWD 331
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
PTZ00420 PTZ00420
coronin; Provisional
 296-374 4.54e-07

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 51.87  E-value: 4.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 296 LVTITGHDSDVLDIAFD-CYGKRLATASTDCTARVWDVSSNFKLIS-------TMEGHKDEVSQVCFNPGGTQVLTASN- 366
Cdd:PTZ00420  67 VIKLKGHTSSILDLQFNpCFSEILASGSEDLTIRVWEIPHNDESVKeikdpqcILKGHKKKISIIDWNPMNYYIMCSSGf 146


                 ....*...
gi 242005915 367 DKTARIWN 374
Cdd:PTZ00420 147 DSFVNIWD 154
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
 249-415 2.27e-06

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 50.09  E-value: 2.27e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 249 RTNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIW-------DPRMFTCLVTITGHDSDVLDIAFDCYGK-RLAT 320
Cdd:PLN00181 471 KADLKQGDLLNSSNLVCAIGFDRDGEFFATAGVNKKIKIFecesiikDGRDIHYPVVELASRSKLSGICWNSYIKsQVAS 550

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 321 ASTDCTARVWDVSSNfKLISTMEGHKDEVSQVCFNPGGTQVL-TASNDKTARIWNPDTG------------CCIQ----- 382
Cdd:PLN00181 551 SNFEGVVQVWDVARS-QLVTEMKEHEKRVWSIDYSSADPTLLaSGSDDGSVKLWSINQGvsigtiktkaniCCVQfpses 629

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 242005915 383 --------------------------VLQGHSDEVfSGVYSYNGDVLMTASKDNTCQIW 415
Cdd:PLN00181 630 grslafgsadhkvyyydlrnpklplcTMIGHSKTV-SYVRFVDSSTLVSSSTDNTLKLW 687
PTZ00420 PTZ00420
coronin; Provisional
 173-291 2.95e-06

coronin; Provisional


Pssm-ID: 240412 [Multi-domain]  Cd Length: 568  Bit Score: 49.18  E-value: 2.95e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 173 LWGHTAEVVTAKFDG-KQQLIATGSMDRTAKLFDVMTGQET--------GTLRGHTAEVTTVDFDKTGNRLITSS-FDST 242
Cdd:PTZ00420  70 LKGHTSSILDLQFNPcFSEILASGSEDLTIRVWEIPHNDESvkeikdpqCILKGHKKKISIIDWNPMNYYIMCSSgFDSF 149

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 242005915 243 VSVWDTRTNKRvGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWDPR 291
Cdd:PTZ00420 150 VNIWDIENEKR-AFQINMPKKLSSLKWNIKGNLLSGTCVGKHMHIIDPR 197
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 166-205 3.59e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 43.46  E-value: 3.59e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 242005915   166 TGNCLRTLWGHTAEVVTAKFDGKQQLIATGSMDRTAKLFD 205
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 377-416 3.77e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 43.46  E-value: 3.77e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 242005915   377 TGCCIQVLQGHSDEVFSGVYSYNGDVLMTASKDNTCQIWK 416
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 123-162 5.26e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 43.07  E-value: 5.26e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 242005915   123 NGKEILTLEGHINAVYSVSFNmPTCNRILTGSFDRTAKLW 162
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFS-PDGKYLASGSDDGTIKLW 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 87-120 5.92e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 42.68  E-value: 5.92e-06
                           10        20        30
                   ....*....|....*....|....*....|....
gi 242005915    87 TLKTHILPVTNVAFDKNGQRCITGSYDRTCKVWN 120
Cdd:smart00320   7 TLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
PTZ00421 PTZ00421
coronin; Provisional
 94-249 1.01e-05

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 47.58  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  94 PVTNVAFDK-NGQRCITGSYDRTCKVWNV-ENG------KEILTLEGHINAVYSVSFNMPTCNRILTGSFDRTAKLWCSQ 165
Cdd:PTZ00421  77 PIIDVAFNPfDPQKLFTASEDGTIMGWGIpEEGltqnisDPIVHLQGHTKKVGIVSFHPSAMNVLASAGADMVVNVWDVE 156

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 166 TGNCLRTLWGHTAEVVTAKFDGKQQLIATGSMDRTAKLFDVMTGQETGTLRGH-TAEVTTVDFDKTGNRLITSSFDST-- 242
Cdd:PTZ00421 157 RGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHaSAKSQRCLWAKRKDLIITLGCSKSqq 236


                 ....*....
gi 242005915 243 --VSVWDTR 249
Cdd:PTZ00421 237 rqIMLWDTR 245
WD40 pfam00400
WD domain, G-beta repeat;
87-120 1.15e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 41.95  E-value: 1.15e-05
                          10        20        30
                  ....*....|....*....|....*....|....
gi 242005915   87 TLKTHILPVTNVAFDKNGQRCITGSYDRTCKVWN 120
Cdd:pfam00400   6 TLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
124-162 1.40e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 41.95  E-value: 1.40e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 242005915  124 GKEILTLEGHINAVYSVSFNmPTCNRILTGSFDRTAKLW 162
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFS-PDGKLLASGSDDGTVKVW 38
PTZ00421 PTZ00421
coronin; Provisional
 137-291 1.42e-05

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 47.20  E-value: 1.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 137 VYSVSFNMPTCNRILTGSFDRTAKLW-------CSQTGNCLRTLWGHTAEVVTAKFD-GKQQLIATGSMDRTAKLFDVMT 208
Cdd:PTZ00421  78 IIDVAFNPFDPQKLFTASEDGTIMGWgipeeglTQNISDPIVHLQGHTKKVGIVSFHpSAMNVLASAGADMVVNVWDVER 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 209 GQETGTLRGHTAEVTTVDFDKTGNRLITSSFDSTVSVWDTRTNKRVGVLIGHRNEISN-ALFNFDCDLIASSSVDKT--- 284
Cdd:PTZ00421 158 GKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAHASAKSQrCLWAKRKDLIITLGCSKSqqr 237


                 ....*...
gi 242005915 285 -AKIWDPR 291
Cdd:PTZ00421 238 qIMLWDTR 245
WD40 pfam00400
WD domain, G-beta repeat;
251-289 2.73e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.79  E-value: 2.73e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 242005915  251 NKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWD 289
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
378-415 3.01e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.79  E-value: 3.01e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 242005915  378 GCCIQVLQGHSDEVFSGVYSYNGDVLMTASKDNTCQIW 415
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
WD40 pfam00400
WD domain, G-beta repeat;
167-205 4.12e-05

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 40.41  E-value: 4.12e-05
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 242005915  167 GNCLRTLWGHTAEVVTAKFDGKQQLIATGSMDRTAKLFD 205
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
PTZ00421 PTZ00421
coronin; Provisional
 256-387 4.16e-05

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 45.65  E-value: 4.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 256 VLIGHRNEISNALFN-FDCDLIASSSVDKTAKIWD-------PRMFTCLVTITGHDSDVLDIAFDCYGKR-LATASTDCT 326
Cdd:PTZ00421  70 ILLGQEGPIIDVAFNpFDPQKLFTASEDGTIMGWGipeegltQNISDPIVHLQGHTKKVGIVSFHPSAMNvLASAGADMV 149

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 242005915 327 ARVWDVSSNfKLISTMEGHKDEVSQVCFNPGGTQVLTASNDKTARIWNPDTGCCIQVLQGH 387
Cdd:PTZ00421 150 VNVWDVERG-KAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIIDPRDGTIVSSVEAH 209
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 250-289 8.31e-05

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 39.60  E-value: 8.31e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 242005915   250 TNKRVGVLIGHRNEISNALFNFDCDLIASSSVDKTAKIWD 289
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
PTZ00421 PTZ00421
coronin; Provisional
 215-353 1.13e-04

coronin; Provisional


Pssm-ID: 173611 [Multi-domain]  Cd Length: 493  Bit Score: 44.11  E-value: 1.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 215 LRGHTAEVTTVDFDKTGN-RLITSSFDSTVSVWD-------TRTNKRVGVLIGHRNEIsnALFNFD---CDLIASSSVDK 283
Cdd:PTZ00421  71 LLGQEGPIIDVAFNPFDPqKLFTASEDGTIMGWGipeegltQNISDPIVHLQGHTKKV--GIVSFHpsaMNVLASAGADM 148

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915 284 TAKIWDPRMFTCLVTITGHDSDVLDIAFDCYGKRLATASTDCTARVWDvSSNFKLISTMEGHKDEVSQVC 353
Cdd:PTZ00421 149 VVNVWDVERGKAVEVIKCHSDQITSLEWNLDGSLLCTTSKDKKLNIID-PRDGTIVSSVEAHASAKSQRC 217
NBCH_WD40 pfam20426
Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at ...
 330-412 2.50e-03

Neurobeachin beta propeller domain; This entry represents the beta propeller domain found at the C-terminus of neurobeachin-like proteins.


Pssm-ID: 466575 [Multi-domain]  Cd Length: 350  Bit Score: 39.67  E-value: 2.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 242005915  330 WDVSsnFKLISTMEG--------HKDEVSQVCFNPGGTQVLTASNDKTARIW------------------NPDTGCCI-- 381
Cdd:pfam20426 102 WENS--FQVISLNDGrmvqsirqHKDVVSCVAVTSDGSILATGSYDTTVMVWevlrgrssekrsrntqteFPRKDHVIae 179

                          90       100       110
                  ....*....|....*....|....*....|....
gi 242005915  382 ---QVLQGHSDEVFSGVYSYNGDVLMTASKDNTC 412
Cdd:pfam20426 180 tpfHILCGHDDIITCLYVSVELDIVISGSKDGTC 213
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH