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Conserved domains on  [gi|240266470|ref|YP_002970820|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Oplurus grandidieri]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475904)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-345 1.81e-136

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 391.49  E-value: 1.81e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   1 MSPMTITLLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  81 TGSWDITQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSSTMLLFMAAT 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 161 STLMGGWGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLWTSSPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 241 TTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTSKHKWRFKPT 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*
gi 240266470 321 QTPiLLSITAPMAILMLPISPLIMQ 345
Cdd:MTH00112 321 KNT-LTATLTTLSTLLLPLSPMILT 344
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-345 1.81e-136

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 391.49  E-value: 1.81e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   1 MSPMTITLLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  81 TGSWDITQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSSTMLLFMAAT 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 161 STLMGGWGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLWTSSPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 241 TTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTSKHKWRFKPT 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*
gi 240266470 321 QTPiLLSITAPMAILMLPISPLIMQ 345
Cdd:MTH00112 321 KNT-LTATLTTLSTLLLPLSPMILT 344
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-276 2.90e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 100.47  E-value: 2.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   23 SHHWLMAWIGLEINTLSIIPII-SKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWDITQMTHTTSN------ 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   96 -----ILLTLALAMKLGLAPTHFWLPEVLQGSTTK-TALIIATWQKLAPMALI-----YQTTNNLSSTMLLFMAATSTLM 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  165 GGWGGLNQTQLRKIMAYSSIAHLGWM---AAITPIMPNILMLNLLIYLLMTTSMFTALVLS------KSKTIQDTTTLWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMliaLGAGTIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrvHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 240266470  236 SSPMLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLI 276
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWI 281
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-296 3.93e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 99.81  E-value: 3.93e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   7 TLLLSSLAtGTIITASSHHWLMAWIGLEINTLSIIPIIS-KQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWD 85
Cdd:COG1007  106 ALLLFATL-GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  86 ITQM-----THTTSNILLTLALAM-------KLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIY-------QTT 146
Cdd:COG1007  185 LAGIaaalaAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLrllveafPGL 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 147 NNLSSTMLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGWM----AAITPIMPNILMLNLLIYLLMTTSMFTALVLS 222
Cdd:COG1007  265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLllglAAGTPLGVSAALFYLLAYLFMNLGAFAVILLL 344

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240266470 223 KSK-----TIQDTTTLWTSSPMLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRL 296
Cdd:COG1007  345 SRKggeaeEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-296 2.33e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.47  E-value: 2.33e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470    6 ITLLLSSLaTGTIITASSHHWLMAWIGLEINTLSI-IPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSW 84
Cdd:TIGR01770 105 YILLLFAL-LGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   85 DITQMTHTTSN------------ILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSST 152
Cdd:TIGR01770 184 NFEDLLLFLSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYILFG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  153 -------MLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGW-MAAITPIMPNILMLNLLIYLLMTTSM---FTALVL 221
Cdd:TIGR01770 264 fseawqiFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEGIKAVLFYIFIYALMSlgaFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  222 SKS------KTIQDTTTLWTSSPMLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLR 295
Cdd:TIGR01770 344 LRSykdewiEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  .
gi 240266470  296 L 296
Cdd:TIGR01770 424 V 424
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-345 1.81e-136

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 391.49  E-value: 1.81e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   1 MSPMTITLLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWH 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  81 TGSWDITQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSSTMLLFMAAT 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 161 STLMGGWGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLWTSSPML 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 241 TTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTSKHKWRFKPT 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330       340
                 ....*....|....*....|....*
gi 240266470 321 QTPiLLSITAPMAILMLPISPLIMQ 345
Cdd:MTH00112 321 KNT-LTATLTTLSTLLLPLSPMILT 344
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-344 7.95e-134

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 384.93  E-value: 7.95e-134
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   1 MSPMTITLLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWH 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  81 TGSWDITQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNlSSTMLLFMAAT 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 161 STLMGGWGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLWTSSPML 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 241 TTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTSKHKWRFKPT 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....
gi 240266470 321 QTPILLSITAPMAILMLPISPLIM 344
Cdd:MTH00135 320 QLTLPLAISTTATLMLLPLTPAIL 343
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-344 2.12e-131

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 378.88  E-value: 2.12e-131
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   1 MSPMTITLLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWH 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  81 TGSWDITQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSSTMLLFMAAT 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 161 STLMGGWGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLWTSSPML 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 241 TTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTSKHKWRFKpT 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFK-N 319

                        330       340
                 ....*....|....*....|....
gi 240266470 321 QTPILLSITAPMAILMLPISPLIM 344
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTIL 343
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-344 1.41e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 328.34  E-value: 1.41e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   1 MSPMTITLLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWH 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  81 TGSWDITQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSSTMLLFMAAT 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 161 STLMGGWGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLWTSSPML 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 241 TTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTSKHKWRFKPT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....
gi 240266470 321 QTPILLSITAPMAILMLPISPLIM 344
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLS 344
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-344 8.61e-93

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 280.32  E-value: 8.61e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   1 MSPMTITLLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWH 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  81 TGSWDITQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSSTMLLFMAAT 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 161 STLMGGWGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLWTSSPML 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 241 TTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTSKHKWRFKPT 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....
gi 240266470 321 QTPILLSITaPMAILMLPISPLIM 344
Cdd:MTH00200 321 SNLLVGLLL-LLSILGLPLTPQLL 343
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-343 3.41e-88

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 268.72  E-value: 3.41e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   1 MSPMTITLLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWH 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  81 TGSWDITQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSSTMLLFMAAT 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 161 STLMGGWGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLWTSSPML 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 241 TTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTSKHKWRFKPT 320
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGN 320

                        330       340
                 ....*....|....*....|....*
gi 240266470 321 QTP--ILLSITAPMAILMLPISPLI 343
Cdd:MTH00041 321 ITVygVILSILSSISILGLLLIPLF 345
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-344 5.07e-54

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 180.40  E-value: 5.07e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   1 MSPMTITLLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWh 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  81 tgswdITQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNlssTMLLFMAAT 160
Cdd:MTH00160  81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINN---NFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 161 STLMGGWGGLNQTQLRKIMAYSSIAHLGWMaaITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKT--IQDTTTLWTSSP 238
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWM--LSSMMISENLWLIYFLIYSIISLSIILLFNKFNIffLNQLFNSNNKSK 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 239 MLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTSKHKWRFK 318
Cdd:MTH00160 231 KIKFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNK 310

                        330       340
                 ....*....|....*....|....*.
gi 240266470 319 PTQTPILLSItapMAILMLPISPLIM 344
Cdd:MTH00160 311 FSLILNFLSF---ISLFGLILSSLLF 333
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 8-337 3.19e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 167.76  E-value: 3.19e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   8 LLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWDit 87
Cdd:MTH00144   8 LFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWF-- 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  88 qmthttSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQT-TNNLSSTMLLFMAATSTLMGG 166
Cdd:MTH00144  86 ------SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFlDLYWLAYLLCVISVLSALVGS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 167 WGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLwTSSPMLTTTMML 246
Cdd:MTH00144 160 IGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIIS 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 247 TLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTSKHKWRFKPTqtpILL 326
Cdd:MTH00144 239 LLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSSI---ISL 315

                        330
                 ....*....|.
gi 240266470 327 SITAPMAILML 337
Cdd:MTH00144 316 NLLGGLLFLLL 326
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 5-341 2.15e-46

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 160.33  E-value: 2.15e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   5 TITLLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLnawhtgSW 84
Cdd:MTH00011   7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTM------MW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  85 DITQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSSTMLLFMAATSTLM 164
Cdd:MTH00011  81 SFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 165 GGWGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLWTSSPMLTTTM 244
Cdd:MTH00011 161 GGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 245 MLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTtsltlspNTTTSKHKWRFKPTQTPI 324
Cdd:MTH00011 241 FIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN-------FMYLSPTFSSLKSAPYEP 313

                        330
                 ....*....|....*..
gi 240266470 325 LLSITAPMAILMLPISP 341
Cdd:MTH00011 314 KTKILISMCTLSLGLIP 330
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 8-339 1.11e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 131.72  E-value: 1.11e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   8 LLLSSLATGTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTgswdit 87
Cdd:MTH00197   2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSNL------ 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  88 qMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIyqtTNNLSSTMLLFMAAT-STLMGG 166
Cdd:MTH00197  76 -YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLIL---AFNSSSFMGLLICSVlSSLIGG 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 167 WGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLSKSKTIQDTTTLWTSSPMLTTTMML 246
Cdd:MTH00197 152 IGGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGL 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 247 TLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTtslTLSPNTTTSKHKWRFKPTQTPILL 326
Cdd:MTH00197 232 SFLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYK---SLILSNWMINFLMKINLLYSGLFI 308

                        330
                 ....*....|...
gi 240266470 327 SITAPMAILMLPI 339
Cdd:MTH00197 309 LLMMMLPLLMIFT 321
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-276 2.90e-24

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 100.47  E-value: 2.90e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   23 SHHWLMAWIGLEINTLSIIPII-SKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWDITQMTHTTSN------ 95
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIgYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   96 -----ILLTLALAMKLGLAPTHFWLPEVLQGSTTK-TALIIATWQKLAPMALI-----YQTTNNLSSTMLLFMAATSTLM 164
Cdd:pfam00361  81 llllfLLILVGFLFKSAQVPFHTWLPDAYEGAPTPvSALLAATLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  165 GGWGGLNQTQLRKIMAYSSIAHLGWM---AAITPIMPNILMLNLLIYLLMTTSMFTALVLS------KSKTIQDTTTLWT 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMliaLGAGTIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrvHTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 240266470  236 SSPMLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLI 276
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWI 281
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
7-296 3.17e-23

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 99.90  E-value: 3.17e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   7 TLLLSSLAtGTIITASSHHWLMAWIGLEINTLSIIPIIS-KQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWD 85
Cdd:PRK05777 107 LLVLFALL-GMMVMVSANDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  86 ITQM-----THTTSNILLTLALAM-------KLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALI----YQTTNNL 149
Cdd:PRK05777 186 FAGIakalaDGSGNSLLLLFGLVFllvglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLlrllVVAFGGL 265

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 150 S---STMLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGWM----AAITPIMPNILMLNLLIYLLMTTSMFTALVLS 222
Cdd:PRK05777 266 SedwQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvglAAGTAEGYSAVLFYLLAYLFMTLGAFGVISLL 345

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240266470 223 KSK-----TIQDTTTLWTSSPMLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRL 296
Cdd:PRK05777 346 RRKggeaeSISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-296 3.93e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 99.81  E-value: 3.93e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   7 TLLLSSLAtGTIITASSHHWLMAWIGLEINTLSIIPIIS-KQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWD 85
Cdd:COG1007  106 ALLLFATL-GMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLN 184

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  86 ITQM-----THTTSNILLTLALAM-------KLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIY-------QTT 146
Cdd:COG1007  185 LAGIaaalaAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLrllveafPGL 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 147 NNLSSTMLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGWM----AAITPIMPNILMLNLLIYLLMTTSMFTALVLS 222
Cdd:COG1007  265 AADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLllglAAGTPLGVSAALFYLLAYLFMNLGAFAVILLL 344

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 240266470 223 KSK-----TIQDTTTLWTSSPMLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRL 296
Cdd:COG1007  345 SRKggeaeEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRV 423
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-296 3.41e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 95.87  E-value: 3.41e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  13 LATGTIITASSHHWLMAWIGLEINTLSI-IPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWDI----- 86
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLsyinl 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  87 --------TQMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSstMLLFMA 158
Cdd:MTH00196  82 vlnsgqsfSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 159 ATSTLMGGWGGLNQTQLRKIMAYSSIAHLG---WMAAITPIMPNILMLNLLIYLLMTTSMFTALVLS---KSKTIQDTTT 232
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFESIQASLVYLFIYIIMSICVFSIILAlnvYKNLIIEFSG 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240266470 233 LWTSSPMLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRL 296
Cdd:MTH00196 240 LSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-188 3.11e-20

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 91.23  E-value: 3.11e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  13 LATGTIITASSHHWLMAWIGLEINTLSI-IPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWDI----T 87
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIqginS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  88 QMTHTTSNILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTtnNLSSTMLLFMAATSTLMGGW 167
Cdd:MTH00199 186 ILTGDVGKILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQI--GPVTNVVLICAVLSIIYGAI 263

                        170       180
                 ....*....|....*....|.
gi 240266470 168 GGLNQTQLRKIMAYSSIAHLG 188
Cdd:MTH00199 264 GALNQTKIKRLLAYSGIGHMG 284
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-296 2.33e-19

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 88.47  E-value: 2.33e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470    6 ITLLLSSLaTGTIITASSHHWLMAWIGLEINTLSI-IPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSW 84
Cdd:TIGR01770 105 YILLLFAL-LGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   85 DITQMTHTTSN------------ILLTLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSST 152
Cdd:TIGR01770 184 NFEDLLLFLSNgmlnisllllgiVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYILFG 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  153 -------MLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGW-MAAITPIMPNILMLNLLIYLLMTTSM---FTALVL 221
Cdd:TIGR01770 264 fseawqiFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYiLIGLLAGTLEGIKAVLFYIFIYALMSlgaFGVLSL 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  222 SKS------KTIQDTTTLWTSSPMLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLR 295
Cdd:TIGR01770 344 LRSykdewiEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  .
gi 240266470  296 L 296
Cdd:TIGR01770 424 V 424
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-190 1.63e-15

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 77.59  E-value: 1.63e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  16 GTIITASSHHWLMAWIGLEINTLSIIPIISKQHHPRAT---------EAATKYFLTQAAASATILFSSTLNAWHTGS--- 83
Cdd:MTH00198 200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegm 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  84 -WDITQMTHTTSNILL----------TLALAMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLapMALIYQTTNNLSST 152
Cdd:MTH00198 280 lGTILSATLETTNIELrqgslgylfiTVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKF--TVYILLTSLVITSK 357

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 240266470 153 MLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGWM 190
Cdd:MTH00198 358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFI 395
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 30-301 3.99e-11

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 63.63  E-value: 3.99e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  30 WIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWDITQMTHTTSNI----------LLT 99
Cdd:COG0651  133 FVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLAELdpglllaafaLLL 212

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 100 LALAMKLGLAPTHFWLPE-----------VLQGSTTKTAL--IIATWQKLAPmaliyQTTNNLSSTMLLFMAATSTLMGG 166
Cdd:COG0651  213 VGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFG-----ADPALFLGTLLLVLGLLTMLVGA 287

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 167 WGGLNQTQLRKIMAYSSIAHLGWMAAITPIMPNILMLNLLIYLLMTTSMFTALVLS--------KSKTIQDTTTLWTSSP 238
Cdd:COG0651  288 LGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLNHALAKALLFLAagaieratGTRDLDKLGGLGKRMP 367

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 240266470 239 MLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTS 301
Cdd:COG0651  368 LTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 3.03e-08

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 49.56  E-value: 3.03e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 240266470  291 FFYLRLTYTTSLTLSPNTTTSKHKWRFKPTQTPILLSITAPMAILMLPISP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 38-188 4.12e-07

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 51.24  E-value: 4.12e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  38 LSIIP---IISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSW--DITQMTHTTSN--------ILLTLALAM 104
Cdd:COG1008  142 LMLIPmyfLIGIWGGERRIYAAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAAPLPltaqlllfLAFFIAFAV 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 105 KLGLAPTHFWLPEVLQGSTTKTALIIA---------------------TWQKLAPMALIyqttnnlsstmllfMAATSTL 163
Cdd:COG1008  222 KVPMFPFHTWLPDAHVEAPTAGSVLLAgvllkmggygllrfalplfpeASAYFAPLLAA--------------LGVIGII 287

                        170       180
                 ....*....|....*....|....*
gi 240266470 164 MGGWGGLNQTQLRKIMAYSSIAHLG 188
Cdd:COG1008  288 YGALVALAQTDLKRLIAYSSVSHMG 312
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 55-190 4.72e-07

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 51.09  E-value: 4.72e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   55 AATKYFLTQAAASATILFSSTLNAW-HTGSWDIT-----QMTHTTSNILLT---LALAMKLGLAPTHFWLPEV-LQGSTT 124
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLYFlGGGTFDLLellnlPLPFGVQTWLFLaffIAFAVKVPLFPLHTWLPDAhVEAPTA 236

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 240266470  125 KTALIIATWQKLAPMALI------YQTTNNLSSTMLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGWM 190
Cdd:TIGR01972 237 GSVILAGVLLKMGTYGFLrfnlplFPDASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFV 308
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
38-196 1.35e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 43.54  E-value: 1.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  38 LSIIPI---ISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWDI---TQMTHT---TSNILL----TLALAM 104
Cdd:PRK06473 138 LELIPLyllIAIWGGQRRGYAATKFLLYTAISGILILVSFLGLVWLSGASSFdyePLRSHTlplSTQLLLlapiLVGFGI 217

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 105 KLGLAPTHFWLPEV-LQGSTTKTALIIATWQKLAPMALI------YQTTNNLSSTMLLFMAATSTLMGGWGGLNQTQLRK 177
Cdd:PRK06473 218 KIPLVPFHTWLPDAhVEASTPVSVLLAGVLLKLGTYGLLrfgvglFPEAWVYLAPWLATWAVVSVLYGASCAIAQKDMKK 297

                        170       180
                 ....*....|....*....|...
gi 240266470 178 IMAYSSIAHLGWM----AAITPI 196
Cdd:PRK06473 298 MVAYSSIGHMGYIllaaAAATPL 320
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-296 1.69e-04

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 43.07  E-value: 1.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  51 RATEAATKYFLTQAAASATIL--FSST--LNAWHTGSWDI------TQMTHTTSN----ILLTLALAMKLGLAPTHFWLP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVygFSWLygLSGGEIELQEIvnglinTQMYNSPGIsialIFITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 117 EVLQGSTTKTALIIATWQKLAPMAL-------IYQTTNNLSSTMLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGW 189
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKVAASALatrifdiPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 190 -MAAITPIMPNILMLNLLIYLLMTTSM----FTALVLSKSKT----IQDTTTLWTSSPMLTTTMMLTLLSLGGLPPLTGF 260
Cdd:CHL00049 319 vIIGIIVGDSNDGYASMITYMLFYIFMnlgtFACIVLFGLRTgtdnIRDYAGLYTKDPFLALSLALCLLSLGGIPPLAGF 398

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 240266470 261 LPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRL 296
Cdd:CHL00049 399 FGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-188 2.04e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 43.10  E-value: 2.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  55 AATKYFLTQAAASATILFSSTLNAWHTG--SWDITQMTHTTSNILLTL--------ALAMKLGLAPTHFWLPEVLQGSTT 124
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDtfTFDLAELGAKSYPLALELllyagfliAFGVKLPIFPLHTWLPDAHGEASA 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 240266470 125 KTALIIA-TWQKLAPMALIYQTTNNLSSTMLLFMAATSTLmgG-----WGGLN---QTQLRKIMAYSSIAHLG 188
Cdd:PRK12561 218 PVSMILAgVLLKMGGYALIRFNVQMLPDAHVYFAPALAIL--GvvniiYGALNafaQDNVKRRLAYSSVSHMG 288
ND5 MTH00207
NADH dehydrogenase subunit 5; Provisional
 27-192 3.31e-04

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 164753 [Multi-domain]  Cd Length: 572  Bit Score: 42.44  E-value: 3.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  27 LMAWIGLEIntLSIIPIISKQHhPRATEAATKYFLTQAAASATILFSS--TLNAWHtgsWDITQMTHTTSNILLTLAL-- 102
Cdd:MTH00207 114 LLGWDGLGL--VSFILVIYYQN-PKSLGAGMITALTNRIGDVMLLLSIgwTLNQGH---WSITNMWQTDMNNYIALSImi 187

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 103 -AM-KLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSST-----MLLFMAATSTLMGGWGGLNQTQL 175
Cdd:MTH00207 188 aAMtKSAQMPFSSWLPAAMAAPTPVSALVHSSTLVTAGVFLLIRFYPFLSSTywfnpALLLTASLTMLMAGLSAMTECDM 267

                        170
                 ....*....|....*..
gi 240266470 176 RKIMAYSSIAHLGWMAA 192
Cdd:MTH00207 268 KKIIALSTLSQLGVMMA 284
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
52-190 5.68e-04

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 41.55  E-value: 5.68e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  52 ATEAATKYFLTQAAASATILFSSTLNAWHTGSWDITQMTHTTSNILLTLALAMKLGLA----------------PTHFWL 115
Cdd:PRK07376 171 AADAAQKAFVVNRVGDFGLLLGILGLFWATGSFDFDGIADRLSELVSSGAVSGWLALLlcilvflgpmaksaqfPLHVWL 250

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 116 PEVLQGSTTKTALIIATWQKLAPMALI---YQTTNNLSSTMLL--FMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGWM 190
Cdd:PRK07376 251 PDAMEGPTPISALIHAATMVAAGVFLVarmYPVFEQFPAVMTViaWTGAITAFLGASIALTQNDIKKGLAYSTISQLGYM 330
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 8-338 9.12e-04

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 41.14  E-value: 9.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   8 LLLSSLATGTIITASSHHWLMAWIGLEINTLS---IIPIISKqhhpRATEAATKYFLTQAAASATILFSSTLNAWHTGSW 84
Cdd:PRK08668 102 MFALMSLAGVLGVFLANDLLTLYIFWEIMTFSsfmMVPMGKK----ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTF 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  85 DIT-------QMTHTTSNILLTLALA----MKLGLAPTHFWLPE-----------VLQGSTTKT-------ALIIATWQK 135
Cdd:PRK08668 178 DFAdisqgliNDTSTGFALIVFLFLLafgvAKAGIFPLHVWAPDayseapqsfsaVLSGQLSKLgaygfllVLYVLPGTK 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 136 LAPMALIYQTTNnLSSTMLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGW----MAAITPIMPNILMLNLLIYLLM 211
Cdd:PRK08668 258 LFSEFGTYRGVP-LFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYilvgLGLGTSLGFAGGLFHVFNHALF 336

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 212 TTSMF--TALVLSKSKT--IQDTTTLWTSSPMLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASL 287
Cdd:PRK08668 337 KGLFFliFAAVIYRTGTtkISEMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSI 416

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|.
gi 240266470 288 LSLFFYLRLTYTTSLTLSPntttSKHKwrfKPTQTPILLSItaPMAILMLP 338
Cdd:PRK08668 417 GSFLYVFRPLAGVFLGQLP----SDHK---DVKEAPLPMLI--PMAILVLL 458
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 38-188 9.29e-04

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 40.96  E-value: 9.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  38 LSIIP---IISKQHHPRATEAATKYFLTQAAASATILFS----STLNAWHTGSWDI-----TQMTHTTSNIL---LTLAL 102
Cdd:PRK05846 142 AMLIPmyfLIGVWGGKNRIYAATKFFLYTLLGSLLMLVAiiylVVVYYNATGTFDIadllnLPLPPGVQYWLflaFFIAF 221

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 103 AMKLGLAPTHFWLPEVLQGSTTKTALIIA-TWQKLAPMALI---YQTTNNLSSTMLLFMAATSTLM---GGWGGLNQTQL 175
Cdd:PRK05846 222 AVKMPMFPLHTWLPDAHVQAPTAGSVLLAgILLKMGAYGLLrfsLPLFPDASHEFAPIIITLGVIAiiyGALVALAQTDI 301

                        170
                 ....*....|...
gi 240266470 176 RKIMAYSSIAHLG 188
Cdd:PRK05846 302 KKLIAYSSISHMG 314
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-337 1.29e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 40.63  E-value: 1.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  33 LEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWDITQM--------THTTSNILLTLALAM 104
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLagalaenpTVVTAFGFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 105 KLGLAPTHFWLPEVLQGSTTK-TALIIATWQKLAPMALI-----------YQTTNNLSSTMLLFMAatSTLMGGWGGLNQ 172
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAAPPVvTALLSGLVTKVAVYALIriyftvfggdfRFALGLGWLLAVLALL--SMLVGSLAALGQ 292

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 173 TQLRKIMAYSSIAHLGWM----AAITPIMPNILMLNLLIYLLMTTSMFTAL----VLSKSKTIQDTTTLWTSSPMLTTTM 244
Cdd:PRK08375 293 DDVKRVLAYSTVSQMGYIllglALLTPLALAAGLLHLLHHALMKGALFLAAgaieVTYGTRRLSELSGLGRRMPLTAAAF 372

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 245 MLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMASLLSLFFYLRLTYTTSLTLSPNTTTskhkwrfkPTQTPI 324
Cdd:PRK08375 373 AVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAFFGPPPPGSE--------APKQEA 444

                        330
                 ....*....|...
gi 240266470 325 LLSITAPMAILML 337
Cdd:PRK08375 445 PLGMLAPSLALAL 457
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 8-191 1.80e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 40.14  E-value: 1.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   8 LLLSSLATGTIITASSHHwlmAWIGLEINTLSIIPIISKQHHPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWDIT 87
Cdd:PRK08377 115 LLLMLGATGMIATGDIFN---LFVFMEITAITAYALTAYNKTGEAAEASMKYIVLGGIGSSFFLIGVALIYGATGTLNMA 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  88 QMTHTTSNI----------LLTLALAMKLGLAPTHFWLPEVLQG-----STTKTALII-ATWQKLAPMALIYQTTNNLSS 151
Cdd:PRK08377 192 HIAQLAGTIdptvaqvglaLLIFGLAVEAELFPLNAWAPDAYQAaphpiTVMFSAFVVkAGLYAMARILYLMQNANGWSS 271

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 240266470 152 T--MLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGWMA 191
Cdd:PRK08377 272 VlkLVIIMATLTVFFAELSALRQKNVKRMIAYSSIGQVGMIA 313
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 96-194 1.92e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 40.29  E-value: 1.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  96 ILLTLALAM-KLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSST-----MLLFMAATSTLMGGWGG 169
Cdd:PRK12644 206 VVLILVGALsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVARLAPGFADVpvwrpTVLVLGLATMLLGGWRA 285

                         90       100
                 ....*....|....*....|....*
gi 240266470 170 LNQTQLRKIMAYSSIAHLGWMAAIT 194
Cdd:PRK12644 286 LRQHDLKLILAYGTVSQLGFLTVLV 310
PRK12650 PRK12650
DUF4040 family protein;
31-192 2.57e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 39.64  E-value: 2.57e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  31 IGLEINTLSIIPIISKQHhPRATEAATKYFLTQAAASATILFSSTLNAWHTGSWDITQMTHTTS---NILLTLALAMKLG 107
Cdd:PRK12650 137 VAWELVSLASFFLIARSG-SGGEAGSIRTLILTFFGGLTLLAAVAIAATQTGTTSLSGILHSDVwaeKPGLTTVVAVLIA 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 108 LA--------PTHFWLPEVLQGSTTKTALIIATWQKLAPMALIYQTTNNLSSTM-----LLFMAATSTLMGGWGGLNQTQ 174
Cdd:PRK12650 216 VAaftksaqfPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFHDVAvwnwlLIIVGMITALMGAVFAVQKTD 295

                        170
                 ....*....|....*...
gi 240266470 175 LRKIMAYSSIAHLGWMAA 192
Cdd:PRK12650 296 LKKLTAYSTVSQLGWIVA 313
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
55-196 2.89e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 39.31  E-value: 2.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  55 AATKYFLTQAAASATILFSSTLNAWHTGSWDITQMTHTTSN-------ILLTLAL---AMKLGLAPTHFWLPEV-LQGST 123
Cdd:PRK07363 158 ASIKFLIYTAVSGLLVLAAFLGIVWLSGSTSFDYDAISTQNlslntqlILLTGLLlgfGIKIPLVPLHTWLPDAyTEASP 237

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 124 TKTALIIATWQKLAPMALI------YQTTNNLSSTMLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGWM----AAI 193
Cdd:PRK07363 238 AVAILLGGVLAKLGTYGLLrfglqlFPQTWSLVAPGLAIIGTISVIYGALSAIAQKDIKRMVAYSSIGHMGYIlvaaAAG 317


                 ...
gi 240266470 194 TPI 196
Cdd:PRK07363 318 TQL 320
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
92-192 3.17e-03

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 39.16  E-value: 3.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  92 TTSNILLTLALAMKLGLAPThFWLPEVLQG-STTKTALIIATWQKLAPMALIYQTT------NNLSSTMLLFMAATSTLM 164
Cdd:PRK12663 207 TTIALLFLLAFGMKAALFPF-MWLPAAYHTpNTEVAALFAALLTKVGIYALIRVFTllfpqeRELLHPLLATMAAITMVI 285

                         90       100
                 ....*....|....*....|....*...
gi 240266470 165 GGWGGLNQTQLRKIMAYSSIAHLGWMAA 192
Cdd:PRK12663 286 GALGALAYKDIRRIAGYQVISSIGFILL 313
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 105-312 3.62e-03

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 39.29  E-value: 3.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 105 KLGLaptHFWLPEVLQGSTTKTALIIATWQ---------------KLAPMALIYQTtnnLSSTMLLFMAATStlmggwgG 169
Cdd:MTH00020 226 QLGL---HTWLPDAMEGPTPVSALIHAATMvtagvfllirssplfEQAPLALIIVT---IVGSLTVFFAATV-------G 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 170 LNQTQLRKIMAYSSIAHLGWMAAITPImpniLMLNLLIYLLMTTSMFTAL----------VLSKSKTIQDTTTLWTSSPM 239
Cdd:MTH00020 293 LVQNDLKKVIAYSTCSQLGYMVVACGL----SHYSISLFHLMNHAFFKALlflsagsvihALSDEQDMRKMGGLISFLPL 368

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 240266470 240 LTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNLIPITTMLAMAS-LLSLFFYLRLTYttsLTLSPNTTTSK 312
Cdd:MTH00020 369 TYIFFLIGSLSLMGFPYLTGFYSKDLILELAFGQYYLIFAYWLGCFSaLLTAFYSIRLIY---LTFLSNTNLKK 439
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 5-299 4.16e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 38.92  E-value: 4.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   5 TITLLLSSLATGTIITASSHHWlmaWIGLEINTLSIIPIISKQHH-PRATEAATKYFLTQAAASATILFSSTLNAWHTGS 83
Cdd:PRK08376 125 TLILLLELGMLGMAITGDLFNF---FVFLEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGIALLYGQYGT 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  84 WDI----TQMTHTTSNI------LLTLALAMKLGLAPTHFWLPEVLQG--STTKTALIIATWQKLAPMA----LIYQTTN 147
Cdd:PRK08376 202 LNMaylaVKMSENPTVVakialaLFIAGLAMKSGAVPVHMWLPDAYPAapSSISAMLLVIKQAGLYALArvlfSIYGPAI 281

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 148 NLSST--MLLFMAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGWM---------AAITPIMPNILMLNLLIYLLMTT--S 214
Cdd:PRK08376 282 NLATVgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMllglgvglaALGDPAMASYGEIALAGGIYHIVnhA 361

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 215 MFTALV-LSKSKTIQDTTT--------LWTSSPMLTTTMMLTLLSLGGLPPLTGFLPKWLIMEELTLQNliPITTMLAM- 284
Cdd:PRK08376 362 LYKALLfLTAGAVIYETGTrnlnelggLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYESSALFN--PILGVIAMi 439

                        330
                 ....*....|....*
gi 240266470 285 ASLLSLFFYLRLTYT 299
Cdd:PRK08376 440 GSVLTLASFVKVFHT 454
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
6-263 5.23e-03

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 38.49  E-value: 5.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470   6 ITLLLSSLATGTIITASSHhWLMAWIGLEinTLSIIPIISK---QHHPRATEAATKYFLTQAAASATILFSSTL----NA 78
Cdd:PRK02504 113 AAILLTATLGGMFLSGATE-LVMIFISLE--TLSIASYLLTgymKRDPRSNEAALKYLLIGAASSAIFLYGSSLlyglSG 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470  79 WHTGSWDITQMTHTTSNILLTLAL-------AMKLGLAPTHFWLPEVLQGSTTKTALIIATWQKLAPMAL---IYQTTNN 148
Cdd:PRK02504 190 GSTQLSAIALALITSPSLGLALALvfviagiAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALairLLVTAFP 269

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 240266470 149 LSSTM--LLF--MAATSTLMGGWGGLNQTQLRKIMAYSSIAHLGW----MAAITPIMPNILMLNLLIYLLMTTSMFTALV 220
Cdd:PRK02504 270 SFDEQwkLLFtaLAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFvmigLVAGTEAGYASMVFYLLAYLFMNLGAFACVI 349

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 240266470 221 LSKSKT----IQDTTTLWTSSPMLTTTMMLTLLSLGGLPPLTGFLPK 263
Cdd:PRK02504 350 LFSLRTgtdqISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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