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Conserved domains on  [gi|238866930|ref|YP_002929410|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Eulemur fulvus mayottensis]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-172 7.75e-75

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 221.60  E-value: 7.75e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930   1 MMYVMFLLSILLVLGFVSISSKPSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930  81 TWGSNVVIWGVVLLGVSVELFMVMWMLEHGGFGVEGVFGGVEDWVSFESKGGGVVREDCLGVASLYGSASWFAAVAGWSL 160
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|..
gi 238866930 161 FVSVLIVIEIIR 172
Cdd:MTH00109 162 FIGVFVIIEITR 173
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-172 7.75e-75

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 221.60  E-value: 7.75e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930   1 MMYVMFLLSILLVLGFVSISSKPSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930  81 TWGSNVVIWGVVLLGVSVELFMVMWMLEHGGFGVEGVFGGVEDWVSFESKGGGVVREDCLGVASLYGSASWFAAVAGWSL 160
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|..
gi 238866930 161 FVSVLIVIEIIR 172
Cdd:MTH00109 162 FIGVFVIIEITR 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
21-170 1.08e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 48.27  E-value: 1.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930   21 SKPSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPETWGSNVVIWGVVLLGVSveL 100
Cdd:pfam00499   5 TSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGLL--L 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930  101 FMVMWMLEHGGFGVEGVFGGVEDWVSFESKGggvvredclgvASLYGSASWFAAVAGWSLFVSVLIVIEI 170
Cdd:pfam00499  83 LALLLLVLLSASLTPAAAAAAPDVGNIEAIG-----------ELLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-172 7.75e-75

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 221.60  E-value: 7.75e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930   1 MMYVMFLLSILLVLGFVSISSKPSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930  81 TWGSNVVIWGVVLLGVSVELFMVMWMLEHGGFGVEGVFGGVEDWVSFESKGGGVVREDCLGVASLYGSASWFAAVAGWSL 160
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|..
gi 238866930 161 FVSVLIVIEIIR 172
Cdd:MTH00109 162 FIGVFVIIEITR 173
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 1.57e-34

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 119.09  E-value: 1.57e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930   1 MMYVMFLLSILLVLGFVSISSKPSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930  81 TWGSNVVIWGVVLLGVSVELFMVMWmlehggfgveGVFGGVEDWVSF-ESKGGGVVREDCLGVASLYGSASWFAAVAGWS 159
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLF----------WGGWYEGSWVVVdELKEFSVLRGDVGGVALMYSSGGGMLVICAWV 150

                        170
                 ....*....|...
gi 238866930 160 LFVSVLIVIEIIR 172
Cdd:MTH00138 151 LLLTLFVVLELTR 163
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 3.89e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 108.01  E-value: 3.89e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930   1 MMYVMFLLSILLVLGFVSISSKPSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930  81 TWGSNVViwgVVLLGVSVELFMVMWMLehggfgvEGVFGGVEDWVSFESKGGGVVREDCLGVASLYGSASWFAAVAGWSL 160
Cdd:MTH00065  81 AWGSWSV---LVYVLFYLLLLIVGYIL-------FGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVL 150

                        170
                 ....*....|..
gi 238866930 161 FVSVLIVIEIIR 172
Cdd:MTH00065 151 LLTLFVVLEVTR 162
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.41e-26

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 98.67  E-value: 1.41e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930   1 MMYVMFLLSILLVLGFVSISSKPSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930  81 TWGSNVVIWGVVLLGVSVELFMVMWmlehggfgVEGVFGGVEDWVSFESKGGGVVREDCLGVASLYGSASWFAAVAGWSL 160
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVV--------GGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGL 152

                        170
                 ....*....|..
gi 238866930 161 FVSVLIVIEIIR 172
Cdd:MTH00115 153 LLTLFVVLELVR 164
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 2.57e-15

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 69.25  E-value: 2.57e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930   1 MMYVMFLLSILLVLGFVSISSKPSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930  81 TWGSNVVIWGVVLLGVSVELFMVMWMlehggfgvegVFGGVEDWVSFESKGGGVVredcLGVASLYGSASWFAAVAGWSL 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFY----------GGWEMLSWMGVDEANNLDL----SGVSDLYSRGFFLLLLGGVVL 146

                        170
                 ....*....|..
gi 238866930 161 FVSVLIVIEIIR 172
Cdd:MTH00214 147 FLVLFVVLELVR 158
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-170 1.39e-09

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 54.14  E-value: 1.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930   1 MMYVMFLLSILLVLGFVSISSkpSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPE 80
Cdd:MTH00045   1 MVFYLFLILMLFGSTLVFYSL--SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930  81 TWGSNVVIwgvvllgvSVELFMVMWMLehggfgvegvfGGVEDWVSFESKGGG-VVREDCLGVASLYGSASWFAAVAGWS 159
Cdd:MTH00045  79 VSNLGEVL--------VLSLLLSLWVF-----------ISFDNFLELSNNNWSlVSLSDLVGSSELYNSGGLYLLLGGFI 139

                        170
                 ....*....|.
gi 238866930 160 LFVSVLIVIEI 170
Cdd:MTH00045 140 LLVALVVALVI 150
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
21-170 1.08e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 48.27  E-value: 1.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930   21 SKPSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEYPETWGSNVVIWGVVLLGVSveL 100
Cdd:pfam00499   5 TSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGLL--L 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866930  101 FMVMWMLEHGGFGVEGVFGGVEDWVSFESKGggvvredclgvASLYGSASWFAAVAGWSLFVSVLIVIEI 170
Cdd:pfam00499  83 LALLLLVLLSASLTPAAAAAAPDVGNIEAIG-----------ELLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 2-78 2.36e-05

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 42.30  E-value: 2.36e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 238866930   2 MYVMFLLSILLVLGFVSISSKpSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMATEEY 78
Cdd:MTH00212   1 MLLSLLLSLLLLLMLLFPLSA-HPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEH 76
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 2-74 6.60e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 35.25  E-value: 6.60e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 238866930   2 MYVMFLLSILLVLGFVSISSKpSPIYGGVGLIISGALGCGIVMGFGGSFMGLMVFLIYLGGMLVVFGYTTAMA 74
Cdd:MTH00152   1 MSLMILLSVCFSLFLLLPLSK-QPLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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