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Conserved domains on  [gi|238866892|ref|YP_002929362|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Eulemur fulvus fulvus]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 2.18e-164

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 462.39  E-value: 2.18e-164
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   1 MKPIVLMPIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  81 SGQWGITNMCNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPNILLLITTL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 241 TITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 238866892 321 KQMFLLPPLIILTTLTLPLSPALLILN 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 2.18e-164

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 462.39  E-value: 2.18e-164
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   1 MKPIVLMPIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  81 SGQWGITNMCNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPNILLLITTL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 241 TITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 238866892 321 KQMFLLPPLIILTTLTLPLSPALLILN 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-286 6.25e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 96.61  E-value: 6.25e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   23 SSHWLLMWIGLEINMLAIIP-ILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMYSGQWGITNMCNQ--------- 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKAltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   93 --LISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLL-TWQKLAPISI--MLQIYPSINP---NILLLITTLSIMV 164
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLirRSLLYLPSSPfiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  165 GGWGGLNQTQLRKIMAYSSIAHMGWMMAILM----YCPSMTMLNLLIYLMLTIAMFTM-----LNINTSTTTLALSNLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGagtiYGIQAAIFHLLTHGLFSAGLFLCagsviYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 238866892  236 KAPTMTITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILA 286
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 9-297 1.87e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 91.93  E-value: 1.87e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892    9 IMLTIFMGTTLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIvinAMYSGQWGIT 87
Cdd:TIGR01770 107 LLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGI---SLIYGFTGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   88 NMCNQLISFS---------------IILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSI--- 149
Cdd:TIGR01770 184 NFEDLLLFLSngmlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  150 ----NPNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLML----TIAMFTML-- 219
Cdd:TIGR01770 264 fseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIyalmSLGAFGVLsl 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  220 ----NINTSTTTLALSNLWNKAPTMTITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLR 295
Cdd:TIGR01770 344 lrsyKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ..
gi 238866892  296 LI 297
Cdd:TIGR01770 424 VV 425
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 9-298 8.54e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 89.79  E-value: 8.54e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   9 IMLTIFMGTTLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMYSGQWGIT 87
Cdd:COG1007  107 LLLFATLGMMLMASANDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLA 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  88 NMCNQL-----ISFSIILALTM-------KLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPN--- 152
Cdd:COG1007  187 GIAAALaaggaNSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPGlaa 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 153 ----ILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSM----TMLNLLIYLMLTIAMFTMLNI--- 221
Cdd:COG1007  267 dwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLlsr 346

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 238866892 222 -NTSTTTLA-LSNLWNKAPTMTITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIY 298
Cdd:COG1007  347 kGGEAEEIEdLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-347 2.18e-164

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 462.39  E-value: 2.18e-164
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   1 MKPIVLMPIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  81 SGQWGITNMCNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPNILLLITTL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTM 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 241 TITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330       340
                 ....*....|....*....|....*..
gi 238866892 321 KQMFLLPPLIILTTLTLPLSPALLILN 347
Cdd:MTH00105 321 KPMTLLPTLIILSTMLLPLTPMLSILE 347
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-346 5.23e-117

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 342.17  E-value: 5.23e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   1 MKPIVLMPIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMY 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  81 SGQWGITNMCNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSiNPNILLLITTL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTM 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 241 TITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQT 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330       340
                 ....*....|....*....|....*.
gi 238866892 321 KQMFLLPPLIILTTLTLPLSPALLIL 346
Cdd:MTH00135 320 QLTLPLAISTTATLMLLPLTPAILAL 345
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-344 7.82e-106

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 313.68  E-value: 7.82e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   1 MKPIVLMPIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  81 SGQWGITNMCNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPNILLLITTL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTM 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 241 TITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFqQT 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRT-KP 319

                        330       340
                 ....*....|....*....|....
gi 238866892 321 KQMFLLPPLIILTTLTLPLSPALL 344
Cdd:MTH00112 320 KKNTLTATLTTLSTLLLPLSPMIL 343
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-346 3.43e-105

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 312.24  E-value: 3.43e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   1 MKPIVLMPIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMY 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  81 SGQWGITNMCNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPNILLLITTL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTM 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 241 TITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFqQT 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330       340
                 ....*....|....*....|....*.
gi 238866892 321 KQMFLLPPLIILTTLTLPLSPALLIL 346
Cdd:MTH00070 320 KTNNLLSLTIILSLMLLPITPTILNL 345
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-346 1.55e-78

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 244.07  E-value: 1.55e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   1 MKPIVLMPIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMY 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  81 SGQWGITNMCNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPNILLLITTL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTM 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 241 TITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQ-- 318
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSgn 320

                        330       340
                 ....*....|....*....|....*...
gi 238866892 319 QTKQMFLLPPLIILTTLTLPLSPALLIL 346
Cdd:MTH00041 321 ITVYGVILSILSSISILGLLLIPLFLSF 348
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-346 5.35e-78

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 242.57  E-value: 5.35e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   1 MKPIVLMPIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMY 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  81 SGQWGITNMCNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPNILLLITTL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTM 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 241 TITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQT 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330       340
                 ....*....|....*....|....*.
gi 238866892 321 KQmFLLPPLIILTTLTLPLSPALLIL 346
Cdd:MTH00200 321 SN-LLVGLLLLLSILGLPLTPQLLFL 345
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 10-315 1.50e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 160.82  E-value: 1.50e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  10 MLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMYSGQWGITNM 89
Cdd:MTH00144  10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSMSL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  90 cnqlisfsIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINP-NILLLITTLSIMVGGWG 168
Cdd:MTH00144  90 --------LLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGSIG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 169 GLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLwNKAPTMTITILISL 248
Cdd:MTH00144 162 GLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIISLL 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 238866892 249 LSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKW 315
Cdd:MTH00144 241 LSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-347 5.01e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 159.60  E-value: 5.01e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   1 MKPIVLMPIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMy 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNML- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  81 sgqwgITNMCNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIypsINPNILLLITTL 160
Cdd:MTH00160  81 -----NLMLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 161 SIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTM 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 241 TITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLtmfptLNNLKMKWQFQQT 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLM-----LNYNKNKWNLKKK 307

                        330       340
                 ....*....|....*....|....*..
gi 238866892 321 KQMFLLPPLIILTTLTLPLSPALLILN 347
Cdd:MTH00160 308 KNKFSLILNFLSFISLFGLILSSLLFL 334
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-312 2.66e-42

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 149.54  E-value: 2.66e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   6 LMPIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMYSGQWG 85
Cdd:MTH00011   8 MFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLLK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  86 ITNmcnqliSFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPNILLLITTLSIMVG 165
Cdd:MTH00011  88 NIT------ALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 166 GWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTMTITIL 245
Cdd:MTH00011 162 GLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLF 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 238866892 246 ISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYStSLTMFPTLNNLK 312
Cdd:MTH00011 242 IMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN-FMYLSPTFSSLK 307
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 11-335 9.46e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 129.41  E-value: 9.46e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  11 LTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVinAMYSGQWGITnmc 90
Cdd:MTH00197   5 FIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGS--LSFSNLYLSL--- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  91 nqLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPIsiMLQIYPSINPNILLLITTLSIMVGGWGGL 170
Cdd:MTH00197  80 --LSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL--LILAFNSSSFMGLLICSVLSSLIGGIGGM 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 171 NQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNINTSTTTLALSNLWNKAPTMTITILISLLS 250
Cdd:MTH00197 156 NQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLS 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 251 LGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIYSTSLTMFPTLNNLKMKWQFQQTKQ---MFLLP 327
Cdd:MTH00197 236 LGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFillMMMLP 315


                 ....*...
gi 238866892 328 PLIILTTL 335
Cdd:MTH00197 316 LLMIFTMI 323
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 9-298 4.15e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 99.71  E-value: 4.15e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   9 IMLTIFMGTTLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMYSGQWGIT 87
Cdd:MTH00199 102 LILIVALGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQ 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  88 NMCNQLIS----FSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINpnILLLITTLSIM 163
Cdd:MTH00199 182 GINSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTN--VVLICAVLSII 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 164 VGGWGGLNQTQLRKIMAYSSIAHMGWMM------------AILMYcpsmtmlnLLIYLMLTIAMFTMLNINTSTTTL--A 229
Cdd:MTH00199 260 YGAIGALNQTKIKRLLAYSGIGHMGFILfgvaigsfesiqASLIY--------MIIYVIMSICSFSIILSLKLTKGLivE 331

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 238866892 230 LSNLWNKAPTMTITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIY 298
Cdd:MTH00199 332 VSGLSRKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQ 400
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-286 6.25e-23

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 96.61  E-value: 6.25e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   23 SSHWLLMWIGLEINMLAIIP-ILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMYSGQWGITNMCNQ--------- 92
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKAltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   93 --LISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLL-TWQKLAPISI--MLQIYPSINP---NILLLITTLSIMV 164
Cdd:pfam00361  81 llLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLirRSLLYLPSSPfiqQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  165 GGWGGLNQTQLRKIMAYSSIAHMGWMMAILM----YCPSMTMLNLLIYLMLTIAMFTM-----LNINTSTTTLALSNLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGagtiYGIQAAIFHLLTHGLFSAGLFLCagsviYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 238866892  236 KAPTMTITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILA 286
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-297 9.27e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 94.71  E-value: 9.27e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  13 IFMGTTLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIV-------------INA 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCAllcgttgglhlsyINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  79 MYSGQWGITNMCNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINpnILLLIT 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVN--ILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 159 TLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM------------AILMYcpsmtmlnLLIYLMLTIAMFTMLNINTSTT 226
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLwgieigsfesiqASLVY--------LFIYIIMSICVFSIILALNVYK 231

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 238866892 227 TL--ALSNLWNKAPTMTITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLI 297
Cdd:MTH00196 232 NLiiEFSGLSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 9-297 1.87e-20

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 91.93  E-value: 1.87e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892    9 IMLTIFMGTTLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIvinAMYSGQWGIT 87
Cdd:TIGR01770 107 LLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGI---SLIYGFTGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   88 NMCNQLISFS---------------IILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSI--- 149
Cdd:TIGR01770 184 NFEDLLLFLSngmlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  150 ----NPNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLML----TIAMFTML-- 219
Cdd:TIGR01770 264 fseaWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIyalmSLGAFGVLsl 343

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  220 ----NINTSTTTLALSNLWNKAPTMTITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLR 295
Cdd:TIGR01770 344 lrsyKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423


                  ..
gi 238866892  296 LI 297
Cdd:TIGR01770 424 VV 425
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 9-298 8.54e-20

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 89.79  E-value: 8.54e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   9 IMLTIFMGTTLTMISSHWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMYSGQWGIT 87
Cdd:COG1007  107 LLLFATLGMMLMASANDLLTLFLGLELLSLSLyVLVAFRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLA 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  88 NMCNQL-----ISFSIILALTM-------KLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPN--- 152
Cdd:COG1007  187 GIAAALaaggaNSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPGlaa 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 153 ----ILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSM----TMLNLLIYLMLTIAMFTMLNI--- 221
Cdd:COG1007  267 dwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFMNLGAFAVILLlsr 346

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 238866892 222 -NTSTTTLA-LSNLWNKAPTMTITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLIY 298
Cdd:COG1007  347 kGGEAEEIEdLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
21-297 7.25e-17

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 81.41  E-value: 7.25e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  21 MISS-HWLLMWIGLEINMLAI-IPILMEKANPRSTEAATKYFLTQATASMLLMFTIvinAMYSGQWGITN---------- 88
Cdd:PRK05777 119 MVSAnDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGM---SLLYGATGSLSfagiakalad 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  89 --MCNQLISFSIIL---ALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQI-------YPSINPNILLL 156
Cdd:PRK05777 196 gsGNSLLLLFGLVFllvGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLlvvafggLSEDWQQVLAI 275

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 157 ITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSM----TMLNLLIYLMLTIAMFTMLNI----NTSTTTL 228
Cdd:PRK05777 276 IAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFMTLGAFGVISLlrrkGGEAESI 355

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 229 A-LSNLWNKAPTMTITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLI 297
Cdd:PRK05777 356 SdFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRVI 425
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-219 1.87e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 68.35  E-value: 1.87e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   9 IMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRST---------EAATKYFLTQATASMLLMFTIvinAM 79
Cdd:MTH00198 193 LVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGC---AL 269

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  80 YSGQWGITNMCNQLISFS-----------------IILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIM 142
Cdd:MTH00198 270 YFGFTGNEGMLGTILSATlettnielrqgslgylfITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL 349

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 143 LQIYpsINPNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWmmaILMYCPSMTMLNL-------LIYLMLTIAM 215
Cdd:MTH00198 350 TSLV--ITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGF---ILIGVSAGTYESLqaswtyaVTYLVSALAS 424


                 ....
gi 238866892 216 FTML 219
Cdd:MTH00198 425 FTVI 428
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 8-301 6.56e-12

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 65.94  E-value: 6.56e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   8 PIMLTIFMGTTLTMISSHWLLMWIGLEINMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMYSGQWGIT 87
Cdd:COG0651  111 PLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMA 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  88 NMCNQLISFS----------IILALTMKLGMTPFHFWVPEV-----TQGISLMSGMLLltwqKLAPISIM---LQIYPSI 149
Cdd:COG0651  191 DLAARLAELDpglllaafalLLVGFGIKAALFPLHFWLPDAypaapSPVSALLSGLLT----KVGVYAILrvlTLLFGAD 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 150 NPN----ILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMYCPSMTMLNLLIYL---MLTIAMFTML--N 220
Cdd:COG0651  267 PALflgtLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhALAKALLFLAagA 346

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 221 INTSTTTLALSNLWNKAPTMTITILISLLSLGGLP---PLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLI 297
Cdd:COG0651  347 IERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAglpPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIF 426


                 ....
gi 238866892 298 YSTS 301
Cdd:COG0651  427 GRAQ 430
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-341 6.11e-10

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 54.19  E-value: 6.11e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 238866892  291 YFYLRLIYSTSLTMFPTLNNLKMKWQFQQTKQMFLLPPLIILTTLTLPLSP 341
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSILLLPLTP 51
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
9-263 9.80e-09

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 56.60  E-value: 9.80e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   9 IMLTIFMGTTLTMISSHWLLMWIGLEinMLAIIPILME---KANPRSTEAATKYFLTQATASMLLMFTI-VINAMYSGQW 84
Cdd:PRK02504 115 ILLTATLGGMFLSGATELVMIFISLE--TLSIASYLLTgymKRDPRSNEAALKYLLIGAASSAIFLYGSsLLYGLSGGST 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  85 GITNMCNQLI---SFSIILALTM-------KLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLA----PISIMLQIYPSIN 150
Cdd:PRK02504 193 QLSAIALALItspSLGLALALVFviagiafKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFD 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 151 PNILLLITTLSIM---VGGWGGLNQTQLRKIMAYSSIAHMGWMMaILMYCP-----SMTMLNLLIYLMLTIAMFT---ML 219
Cdd:PRK02504 273 EQWKLLFTALAILsmvLGNVVALAQTSMKRMLAYSSIGQAGFVM-IGLVAGteagyASMVFYLLAYLFMNLGAFAcviLF 351

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 238866892 220 NINTSTTTLA-LSNLWNKAPTMTITILISLLSLGGLPPLTGFLPK 263
Cdd:PRK02504 352 SLRTGTDQISdYAGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGK 396
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 55-191 4.18e-07

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 51.48  E-value: 4.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892   55 AATKYFLTQATASMLLMFTIVINAMYSGQ-WGITNMCNQLISFS--------IILALTMKLGMTPFHFWVPEV-----TQ 120
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLELLNLPLPFGvqtwlflaFFIAFAVKVPLFPLHTWLPDAhveapTA 236

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 238866892  121 GISLMSGMLLltwqKLAPISIM---LQIYPS---INPNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:TIGR01972 237 GSVILAGVLL----KMGTYGFLrfnLPLFPDaslYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 54-191 6.61e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 50.87  E-value: 6.61e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  54 EAATKYFLTQATASMLLMFTIvinAMYSGQWGITNMCNQLISFS-------------IILALTMKLGMTPFHFWVPEV-T 119
Cdd:PRK08376 172 EAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMAYLAVKMSenptvvakialalFIAGLAMKSGAVPVHMWLPDAyP 248

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 238866892 120 QGISLMSGMLLLTWQK--LAPISIMLQIY-PSINPN----ILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK08376 249 AAPSSISAMLLVIKQAglYALARVLFSIYgPAINLAtvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYML 327
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-192 1.96e-06

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 49.31  E-value: 1.96e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  55 AATKYFLTQATASMLLMFTIVINAMYSGQW--GITNMCNQLISFS--------IILALTMKLGMTPFHFWVPEV-----T 119
Cdd:COG1008  162 AAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAAPLPLTaqlllflaFFIAFAVKVPMFPFHTWLPDAhveapT 241

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 238866892 120 QGISLMSGMLLltwqKLAP---ISIMLQIYP---SINPNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMA 192
Cdd:COG1008  242 AGSVLLAGVLL----KMGGyglLRFALPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-243 3.16e-05

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 45.41  E-value: 3.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  55 AATKYFLTQATASMLLMFTIVINAMYSGqwGITNMCNQLISFSIILALTM------------KLGMTPFHFWVP----EV 118
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGD--TFTFDLAELGAKSYPLALELllyagfliafgvKLPIFPLHTWLPdahgEA 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 119 TQGISLMSGMLLLTWQKLAPISIMLQIYPSIN---PNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM---- 191
Cdd:PRK12561 216 SAPVSMILAGVLLKMGGYALIRFNVQMLPDAHvyfAPALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVLlgia 295

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 238866892 192 AILMYCPSMTMLNLLIYLMLTIAMFTMLNIN-TSTTTLALSNLWNKAPTMTIT 243
Cdd:PRK12561 296 AFTDLGISGAMLQMISHGLIAAALFFLTGVTyERTHTLSIPNMGGLAKVMPKT 348
ND5 MTH00207
NADH dehydrogenase subunit 5; Provisional
 82-286 4.17e-05

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 164753 [Multi-domain]  Cd Length: 572  Bit Score: 45.14  E-value: 4.17e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  82 GQWGITNM----CNQLISFSIILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINP-----N 152
Cdd:MTH00207 165 GHWSITNMwqtdMNNYIALSIMIAAMTKSAQMPFSSWLPAAMAAPTPVSALVHSSTLVTAGVFLLIRFYPFLSStywfnP 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 153 ILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILmycpSMTMLNLLIYLMLTIAMF---------TMLNINT 223
Cdd:MTH00207 245 ALLLTASLTMLMAGLSAMTECDMKKIIALSTLSQLGVMMASL----GLGMPKLALFHLITHALFkallfvcagSLIHSHH 320

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 238866892 224 STTTL-ALSNLWNKAPTMTITILISLLSLGGLPPLTGFLPKWIIAQELTKNNNIMLATTMTILA 286
Cdd:MTH00207 321 HSQDLrTMGNLTNQMPLTTSCLLIANLALCGSPFLSGFYSKDLILESSLFYPHNSLMILMIFLA 384
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-191 1.30e-04

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 43.65  E-value: 1.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  55 AATKYFLTQATASMLLMFTI----VINAMYSGQWGITNMCN--------QLISFSIILALTMKLGMTPFHFWVPEV---- 118
Cdd:PRK05846 162 AATKFFLYTLLGSLLMLVAIiylvVVYYNATGTFDIADLLNlplppgvqYWLFLAFFIAFAVKMPMFPLHTWLPDAhvqa 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 119 -TQGISLMSGMLLltwqKLAP---ISIMLQIYPSINPNILLLITTLSIMV---GGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK05846 242 pTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEFAPIIITLGVIAiiyGALVALAQTDIKKLIAYSSISHMGFVT 317
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-297 2.36e-04

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 42.68  E-value: 2.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  51 RSTEAATKYFLTQATASMLLMFTIVINAMYSGQ----WGI------TNMCNQLISF----SIILALTMKLGMTPFHFWVP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGFSWLYGLSGGeielQEIvnglinTQMYNSPGISialiFITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 117 EVTQG-----------ISLMSGMLLLTwqklapiSIMLQIYPSINP---NILLLITTLSIMVGGWGGLNQTQLRKIMAYS 182
Cdd:CHL00049 239 DVYEGsptpvvaflsvTSKVAASALAT-------RIFDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKRMLAYS 311

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 183 SIAHMGWMM-AILMYCPSMTMLNLLIYLMLTIAM-------FTMLNINTSTTTLA-LSNLWNKAPTMTITILISLLSLGG 253
Cdd:CHL00049 312 SIGQIGYVIiGIIVGDSNDGYASMITYMLFYIFMnlgtfacIVLFGLRTGTDNIRdYAGLYTKDPFLALSLALCLLSLGG 391

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 238866892 254 LPPLTGFLPKWIIAQELTKNNNIMLATTMTILALLNLYFYLRLI 297
Cdd:CHL00049 392 IPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKII 435
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
98-206 7.55e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 41.24  E-value: 7.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  98 IILALTMKLGMTPFHFWVP----EVTQGISLMSGMLLLTWQKLAPISIMLQIYP---SINPNILLLITTLSIMVGGWGGL 170
Cdd:PRK07363 211 LLLGFGIKIPLVPLHTWLPdaytEASPAVAILLGGVLAKLGTYGLLRFGLQLFPqtwSLVAPGLAIIGTISVIYGALSAI 290

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 238866892 171 NQTQLRKIMAYSSIAHMGWmmaILMYCPSMTMLNLL 206
Cdd:PRK07363 291 AQKDIKRMVAYSSIGHMGY---ILVAAAAGTQLSLL 323
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-191 7.77e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 41.28  E-value: 7.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  17 TTLTMISSHWLLMWIGLEINML---AIIPILMEKANprsTEAATKYFLTQATA------SMLLMFTIVINAMYSGQWGIT 87
Cdd:PRK08676 115 ITFAFFSDNLALFWIFAELTTVfsaMLIAILSAREN---IDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNWT 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  88 NMCNQ---------LISFSIIL-ALTMKLGMTPFHFWVPEV-TQGISLMSGMLLLTWQKLAPISImLQIYP--------S 148
Cdd:PRK08676 192 ELAAHasllspsvlGASFLFIFiGFLAKSGLVPFHTWLPAAyAKAPSVVSALLSGTVLNIGIYGI-LRLSAllrqsgaaE 270

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 238866892 149 INPNILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK08676 271 QFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLML 313
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 93-211 1.42e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 40.42  E-value: 1.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  93 LISFSIILALTMKLGMTPFHFWVPEV-----TQGISLMSGMLLltwqKLAP---ISIMLQIYPSINPNILLLITTLSIMV 164
Cdd:MTH00217 207 FIFLGFFLSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KLGGygfIRFSWPLLPEASEYFSPLIQTLSLLA 282

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 238866892 165 GGWGGLN---QTQLRKIMAYSSIAHMGwMMAILMYCPSMTMLNLLIYLML 211
Cdd:MTH00217 283 IIYGSLTtcrQVDLKRIIAYSSVAHMG-LVTLGIFSHTIQGLVAAIFLML 331
PRK12650 PRK12650
DUF4040 family protein;
110-192 2.45e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 39.64  E-value: 2.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892 110 PFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYP--SINP--NILLLITTL-SIMVGGWGGLNQTQLRKIMAYSSI 184
Cdd:PRK12650 226 PFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPvfHDVAvwNWLLIIVGMiTALMGAVFAVQKTDLKKLTAYSTV 305


                 ....*...
gi 238866892 185 AHMGWMMA 192
Cdd:PRK12650 306 SQLGWIVA 313
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 94-219 3.12e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 39.13  E-value: 3.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  94 ISFSIILALTMKLGMTPFHFWVPEV-----TQGISLMSGMLL---------LTW-------QKLAPISIMLQIypsinpn 152
Cdd:MTH00226 232 IFLGIFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILLklggyglvrLSWpilplgaQNLAPAVIAMGI------- 304

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 238866892 153 illlittLSIMVGGWGGLNQTQLRKIMAYSSIAHMGwMMAILMYCPSMTMLNLLIYLMLTIAMFTML 219
Cdd:MTH00226 305 -------VGIVYGSFATCRQIDVKRLVAYSSVAHMG-LVSITLVTHDIIGLTGSIFIMLAHGIVSSL 363
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 11-191 5.63e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 38.44  E-value: 5.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  11 LTIFMGTTLTMISSHWLLMWIGLEINMLA-IIPILMEKAnpRSTEAATKYFLTQATASMLLMFTIVINAMYSGQWGITNM 89
Cdd:PRK08668 105 LMSLAGVLGVFLANDLLTLYIFWEIMTFSsFMMVPMGKK--ESRKASLKYFVLSAIGAYAMLYAIFLIYAKTGTFDFADI 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  90 CNQLISFS-----------IILALTMKLGMTPFHFWVPEVTQG-----ISLMSGMLLLTWQKLAPISIMLQIYPSINPN- 152
Cdd:PRK08668 183 SQGLINDTstgfalivflfLLAFGVAKAGIFPLHVWAPDAYSEapqsfSAVLSGQLSKLGAYGFLLVLYVLPGTKLFSEf 262

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 238866892 153 -----------ILLLITTLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK08668 263 gtyrgvplfnyILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYIL 312
PRK12649 PRK12649
putative monovalent cation/H+ antiporter subunit A; Reviewed
 11-196 5.86e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 183649 [Multi-domain]  Cd Length: 789  Bit Score: 38.66  E-value: 5.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  11 LTIFMGTTLTMI-SSHWLLMWIGLEI-NMLAIIPILMEKANPRSTEAATKYFLTQATASMLLMFTIVINAMYSGQWGITN 88
Cdd:PRK12649 117 LLLFMGSMIGMVfSGNTIQLFIFWELtSITSFMLIGYWRHRPESVYGATKSLLITAGGGLFMFAGFLLLHVITGTYDIAT 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  89 MCN--QLIS-------FSIILALTM-----KLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYP--SINPN 152
Cdd:PRK12649 197 ILQdsELIEnikghplFLITLILIFigaaaKSAQGPFYIWLPNAMEAPTPVSAFLHSATMVKAGVYLVARIHPifSGTEA 276

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 238866892 153 ILLLIT---TLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMMAILMY 196
Cdd:PRK12649 277 WFILVSgtgMITMVLAGFLAFRQTDIKAILAYSTISQLAYLMTMYGY 323
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 98-222 6.64e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 37.93  E-value: 6.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  98 IILALTMKLGMTPFHFWVPEVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINPNILLLITTLSIMVggwgGLNQTQLRK 177
Cdd:MTH00091  63 QFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSYKN 138

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 238866892 178 IMAYSSIAHMGWMMAILMYCPSMTMLNLLIYLMLTIAMFTMLNIN 222
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNNV 183
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 98-191 7.53e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 37.94  E-value: 7.53e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238866892  98 IILALTMKLGMTPFHFWVP----EVTQGISLMSGMLLLTWQKLAPISIMLQIYPSINP------NILLLITTLSIMVGGW 167
Cdd:PRK08375 208 VLLALALKAAVFPLHTWLPraypAAPPVVTALLSGLVTKVAVYALIRIYFTVFGGDFRfalglgWLLAVLALLSMLVGSL 287

                         90       100
                 ....*....|....*....|....
gi 238866892 168 GGLNQTQLRKIMAYSSIAHMGWMM 191
Cdd:PRK08375 288 AALGQDDVKRVLAYSTVSQMGYIL 311
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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