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Conserved domains on  [gi|229890381|sp|Q99UX0|]
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RecName: Full=Probable heme-iron transport system permease protein IsdF; AltName: Full=Iron-regulated surface determinant protein F; AltName: Full=Staphylococcal iron-regulated protein G

Protein Classification

FecCD family ABC transporter permease( domain architecture ID 10001816)

FecCD family ABC transporter permease such as iron ABC transporter permease, which is the transmembrane subunit (TM) found in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter involved in the import of iron and iron-containing compounds

CATH:  1.10.3470.10
Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
SCOP:  4002900
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 25-314 2.04e-61

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


:

Pssm-ID: 440374  Cd Length: 306  Bit Score: 197.60  E-value: 2.04e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  25 SFVTGTIKLSFNDLFTKFTTGSNEAVDSII--DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMR 102
Cdd:COG0609    1 SLSLGAVPISLSDVLRALLGPDGDPTADLIvwDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 103 ALCMLFIPQL-YFYLPLLSFIGGLIPFLIIILLHSKF-RFNAVSMILVGVALFVLLNGVLEILT--------QNPLMKIP 172
Cdd:COG0609   81 VLAIVLGGGLsALGLPLAAFLGALLAALLVYLLARRGgGLSPLRLVLAGVAVSALFSALTSLLLlladpeqlRSIVFWLM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 173 QGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGII 252
Cdd:COG0609  161 GSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLV 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 229890381 253 VPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLI 314
Cdd:COG0609  241 VPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLL 302
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 25-314 2.04e-61

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 197.60  E-value: 2.04e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  25 SFVTGTIKLSFNDLFTKFTTGSNEAVDSII--DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMR 102
Cdd:COG0609    1 SLSLGAVPISLSDVLRALLGPDGDPTADLIvwDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 103 ALCMLFIPQL-YFYLPLLSFIGGLIPFLIIILLHSKF-RFNAVSMILVGVALFVLLNGVLEILT--------QNPLMKIP 172
Cdd:COG0609   81 VLAIVLGGGLsALGLPLAAFLGALLAALLVYLLARRGgGLSPLRLVLAGVAVSALFSALTSLLLlladpeqlRSIVFWLM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 173 QGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGII 252
Cdd:COG0609  161 GSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLV 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 229890381 253 VPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLI 314
Cdd:COG0609  241 VPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLL 302
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 19-314 9.29e-51

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 170.40  E-value: 9.29e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381   19 IATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSII-DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSG 97
Cdd:pfam01032   3 LLLILLSLFIGAVKISPSDVFSALLGGDDSLAALIVlDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381   98 ALIMRALCMLFIPQL-YFYLPLLSFIGGLIPFLII-ILLHSKFRFNAVSMILVGVALFVLLNGVLEILT--------QNP 167
Cdd:pfam01032  83 AALGAVLAILLGGSLsLFALPLAAFIGALLAALLVyFLSRGRGGASPLRLILAGIAVSALLSALTSLLLlllnpealQSI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  168 LMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLA 247
Cdd:pfam01032 163 LFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIG 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 229890381  248 FLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLI 314
Cdd:pfam01032 243 FVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLL 309
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
19-314 2.49e-45

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 156.36  E-value: 2.49e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  19 IATAYISFVTGTIKLSFNDLFTKFTTGsNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGA 98
Cdd:PRK09777  14 AGCALLSLRMGVIPLPWRALLTDWQAG-DEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNHAA 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  99 LIMRALCMLFIPQLYFY-LPLLSFIGGLIPFLIIILL---HSKFRfnavsMILVGVAL---------FVLLNGVLEIltQ 165
Cdd:PRK09777  93 SLASVGALLLFPSLPVMwLPLLAFIGGMAGLILLKMLagtHQPMK-----LALTGVALsalwasltdYLMLSRPQDI--N 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 166 NPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQ 245
Cdd:PRK09777 166 NALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGP 245

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 229890381 246 LAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLI 314
Cdd:PRK09777 246 ISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLL 314
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 61-314 3.03e-30

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 115.35  E-value: 3.03e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  61 ILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLY-FYLPLLSFIGGLIPFLIIILLHSKFR 139
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSnYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 140 FNAVSMILVGVAL---FVLLNGVLEILTQNPLMKIPQGLTMKI----WSDVYILAVSALLGLILTLLLSPKLNLLNLDDI 212
Cdd:cd06550   81 LSPSKLILIGIVLsafFSAGVILISLLSDDSLQDLNIWLFGSIlgvtWEDLLILLIILLLVLLLLLLLSRKLNLLTFDED 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 213 QARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQp 292
Cdd:cd06550  161 LAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL- 239

                        250       260
                 ....*....|....*....|..
gi 229890381 293 PLEIPANAILMIVGGPMLIYLI 314
Cdd:cd06550  240 PSELPVGPVTALLGAPYFLYLL 261
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 51-319 1.57e-27

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 109.56  E-value: 1.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381   51 DSII-DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLYfyLPLLSFIGGLIPFL 129
Cdd:TIGR03869  46 DAIVwDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVAVL--LPVAAFAGALLALA 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  130 III-LLHSKFRFNAVSMILVGVALFVLLNGVLEILT---------QNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLL 199
Cdd:TIGR03869 124 ATLgLARTLGTLTPTRTILAGLAVSQLCAAVTSFVIfwsatgdsyREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLA 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  200 LSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWL 279
Cdd:TIGR03869 204 SGRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRHRLLLPVSALAGAVF 283

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 229890381  280 LLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQR 319
Cdd:TIGR03869 284 LVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
 
Name Accession Description Interval E-value
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 25-314 2.04e-61

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 197.60  E-value: 2.04e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  25 SFVTGTIKLSFNDLFTKFTTGSNEAVDSII--DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMR 102
Cdd:COG0609    1 SLSLGAVPISLSDVLRALLGPDGDPTADLIvwDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 103 ALCMLFIPQL-YFYLPLLSFIGGLIPFLIIILLHSKF-RFNAVSMILVGVALFVLLNGVLEILT--------QNPLMKIP 172
Cdd:COG0609   81 VLAIVLGGGLsALGLPLAAFLGALLAALLVYLLARRGgGLSPLRLVLAGVAVSALFSALTSLLLlladpeqlRSIVFWLM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 173 QGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGII 252
Cdd:COG0609  161 GSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLV 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 229890381 253 VPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLI 314
Cdd:COG0609  241 VPHIARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLL 302
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 19-314 9.29e-51

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 170.40  E-value: 9.29e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381   19 IATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSII-DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSG 97
Cdd:pfam01032   3 LLLILLSLFIGAVKISPSDVFSALLGGDDSLAALIVlDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381   98 ALIMRALCMLFIPQL-YFYLPLLSFIGGLIPFLII-ILLHSKFRFNAVSMILVGVALFVLLNGVLEILT--------QNP 167
Cdd:pfam01032  83 AALGAVLAILLGGSLsLFALPLAAFIGALLAALLVyFLSRGRGGASPLRLILAGIAVSALLSALTSLLLlllnpealQSI 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  168 LMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLA 247
Cdd:pfam01032 163 LFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIG 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 229890381  248 FLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLI 314
Cdd:pfam01032 243 FVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLL 309
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
19-314 2.49e-45

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 156.36  E-value: 2.49e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  19 IATAYISFVTGTIKLSFNDLFTKFTTGsNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGA 98
Cdd:PRK09777  14 AGCALLSLRMGVIPLPWRALLTDWQAG-DEHYYVLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDILGVNHAA 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  99 LIMRALCMLFIPQLYFY-LPLLSFIGGLIPFLIIILL---HSKFRfnavsMILVGVAL---------FVLLNGVLEIltQ 165
Cdd:PRK09777  93 SLASVGALLLFPSLPVMwLPLLAFIGGMAGLILLKMLagtHQPMK-----LALTGVALsalwasltdYLMLSRPQDI--N 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 166 NPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQ 245
Cdd:PRK09777 166 NALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGVAACGP 245

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 229890381 246 LAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLI 314
Cdd:PRK09777 246 ISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLL 314
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
33-319 1.09e-39

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 147.68  E-value: 1.09e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  33 LSFNDLFTKFTTGSNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQL 112
Cdd:PRK10577 373 LSFGRDAHGWNWLSGQLLDALLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGA 452

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 113 YF-YLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLEILTQNPLMKIPQGLT-------MKIWSDVY 184
Cdd:PRK10577 453 GFgWLLAAALLGALAALALILLLARRGGFAPERLLLTGIALSALFTALIQLLLASGDPRAAQLLTwlsgstyGVTWAQAL 532

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 185 ILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGN 264
Cdd:PRK10577 533 PLLIVAVLLLALALLLRRWLDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGRR 612

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 229890381 265 YRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQR 319
Cdd:PRK10577 613 ARPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSRR 667
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 19-321 2.14e-34

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 128.31  E-value: 2.14e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  19 IATAYISFVTGTIKLSFNDLFTKFTtGSNEAVDSII--DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSS 96
Cdd:COG4779   34 LALAVLALTLGDYPLSPGDVLRALL-GEGDPGASFVvlELRLPRALAALLVGAALGLSGAIFQSLTRNPLASPDIIGITA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  97 GALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLE-ILTQNPLMKIPQG- 174
Cdd:COG4779  113 GASAGAVAAIVVLGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTAVNSyLLTRADLEDAQSAa 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 175 ------LTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAF 248
Cdd:COG4779  193 vwltgsLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAVALAAVATAAAGPIAF 272

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 229890381 249 LGIIVPHVVRKLVGGNYRVLIPfSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNR 321
Cdd:COG4779  273 VALAAPQIARRLTRSPGPPLLP-SALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLLIRENRRG 344
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
53-313 2.31e-34

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 127.89  E-value: 2.31e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  53 IIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLY--FYLPLLSFIGGLIPFLI 130
Cdd:PRK11228  47 VQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSALSPTPFagYSLAFIAACGGGLSWLL 126

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 131 IILLHSKFRFNAVS--MILVGVALFVLLNGVLEIL-------TQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLS 201
Cdd:PRK11228 127 VMTAGGGWRHTHDRnrLILAGIALSALCMALTRITlllaedhAYGIFYWLAGGVSHARWQEVWQLLPFVVTAVPVVLLLA 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 202 PKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLL 281
Cdd:PRK11228 207 NQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPMSMLLGATLML 286

                        250       260       270
                 ....*....|....*....|....*....|..
gi 229890381 282 VADLLGRVIQPPLEIPANAILMIVGGPMLIYL 313
Cdd:PRK11228 287 LADLLARALAFPGELPAGAVLALIGAPCFVWL 318
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
19-314 4.71e-34

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 131.50  E-value: 4.71e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  19 IATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSII--DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSS 96
Cdd:PRK10577  22 LLALALTLTQLSAALPLSQWLQALWGPDADDLEQLLlhYSRLPRLAIALLVGAALGLAGALLQQVLRNPLASPTTLGVAA 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  97 GALIMRALCMLFIPQLYFYLP-LLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLL---NGVLEILTQNPLMKIP 172
Cdd:PRK10577 102 GAQLALVLATLFAPALLALASqLAAFAGGLLAAALVFALAGGKRLSPLRLVLAGMVVSLYLgalTTLLLLFNEQYLQGLF 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 173 Q----GLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAF 248
Cdd:PRK10577 182 LwgagSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALALAVLLSAAVVSAVGPIGF 261

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 229890381 249 LGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPL--EIPANAILMIVGGPMLIYLI 314
Cdd:PRK10577 262 IGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLAGVGgeLLPTGAVTALIGAPLLLWLL 329
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 61-314 3.03e-30

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 115.35  E-value: 3.03e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  61 ILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLY-FYLPLLSFIGGLIPFLIIILLHSKFR 139
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLSnYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 140 FNAVSMILVGVAL---FVLLNGVLEILTQNPLMKIPQGLTMKI----WSDVYILAVSALLGLILTLLLSPKLNLLNLDDI 212
Cdd:cd06550   81 LSPSKLILIGIVLsafFSAGVILISLLSDDSLQDLNIWLFGSIlgvtWEDLLILLIILLLVLLLLLLLSRKLNLLTFDED 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 213 QARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQp 292
Cdd:cd06550  161 LAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL- 239

                        250       260
                 ....*....|....*....|..
gi 229890381 293 PLEIPANAILMIVGGPMLIYLI 314
Cdd:cd06550  240 PSELPVGPVTALLGAPYFLYLL 261
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 53-321 1.98e-29

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 114.56  E-value: 1.98e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  53 IIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLY-FYLPLLSFIGGLIPFLII 131
Cdd:COG4139   51 VWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGISNGAGVGLVLVVLLGGGLLpPWLLSLAAIAGALLVTLL 130

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 132 ILLHSKFRFNAVSMILVGVALFVLLNGVLEILTQ-NPLMKIPQ-------GLTMKIWSDVYILAVsALLGLILTLLLSPK 203
Cdd:COG4139  131 LLAFARRRLSNARLLLIGVALGIICSAIMTWAVYfSSSLDLRQlmywmmgSFGGVDWRQLWLLLA-LLPVLLWLCLQGKP 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 204 LNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVA 283
Cdd:COG4139  210 LNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAALLLLA 289

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 229890381 284 DLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNR 321
Cdd:COG4139  290 DIIARLALSSAELPIGVVTATLGAPVFIWLLLRRRKIR 327
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
 51-319 1.57e-27

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 109.56  E-value: 1.57e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381   51 DSII-DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLYfyLPLLSFIGGLIPFL 129
Cdd:TIGR03869  46 DAIVwDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVAVL--LPVAAFAGALLALA 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  130 III-LLHSKFRFNAVSMILVGVALFVLLNGVLEILT---------QNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLL 199
Cdd:TIGR03869 124 ATLgLARTLGTLTPTRTILAGLAVSQLCAAVTSFVIfwsatgdsyREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLA 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  200 LSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWL 279
Cdd:TIGR03869 204 SGRVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRHRLLLPVSALAGAVF 283

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 229890381  280 LLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQR 319
Cdd:TIGR03869 284 LVWADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
btuC PRK09535
cobalamin ABC transporter permease BtuC;
53-314 8.13e-27

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 108.30  E-value: 8.13e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  53 IIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIII 132
Cdd:PRK09535  91 VLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVPFGLQAAAFAGALVAAFGVY 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 133 LLHSKF-RFNAVSMILVGVALFVLLNGVLEILTQNP----------LMKIPQGLTmkiWSDVYILAVSALLGLILTLLLS 201
Cdd:PRK09535 171 AIATENgRTPVATLLLAGVAVQTFLGAVISYLLLHSgeslrravywLMGHLHGST---WSDVEVALPVVVVGFVVLLAYA 247

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 202 PKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLL 281
Cdd:PRK09535 248 RDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLPTSALAGASFLV 327

                        250       260       270
                 ....*....|....*....|....*....|...
gi 229890381 282 VADLLGRviQPPLEIPANAILMIVGGPMLIYLI 314
Cdd:PRK09535 328 ATDTVAR--SGPAEVPVGIVTAALGAPFFLYLL 358
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 53-321 1.48e-26

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 106.96  E-value: 1.48e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  53 IIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQL--YFYLPLLSFIGGLIPFLI 130
Cdd:PRK03784  54 VWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLlpPWALSLCAIAGALLITLI 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 131 IILLHSKFRFNAVSMILVGVALFVLLNGVL-------EILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPK 203
Cdd:PRK03784 134 LLRFARRHRLSTSRLLLAGVALGIICSALMtwavyfsTSLDLRQLMYWMMGGFGGVDWRQSWLMLALLPVLIWLCCQGRP 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 204 LNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVA 283
Cdd:PRK03784 214 LNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASLLLLA 293

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 229890381 284 DLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNR 321
Cdd:PRK03784 294 DIVARLALASAELPIGVVTATLGAPVFIWLLLRSHRAR 331
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
44-319 5.51e-20

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 88.61  E-value: 5.51e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  44 TGSNEAVDSII--DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFI----PQLYFylp 117
Cdd:PRK10441  45 SGTCQSADCTIvlDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFgyssAQEQL--- 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 118 LLSFIGGLIPFLIIILLHSK--FRFNAVSMILVGVALFVLLNGVLE-ILTQNPL----MKIPQGLTMKI--WSDVYILAV 188
Cdd:PRK10441 122 AMAFAGALVASLIVAFTGSQggGQLSPVRLTLAGVALAAVLEGLTSgIALLNPDvydqLRFWQAGSLDIrnLHTLKVVLI 201

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 189 SALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVL 268
Cdd:PRK10441 202 PVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWS 281

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 229890381 269 IPFSTVIGAWLLLVADLLGRVIQPPlEIPANAILMIVGGPMLIYLICQSQR 319
Cdd:PRK10441 282 LPVTLLATPALLLFADIIGRLLVPG-ELRVSVVSAFIGAPVLIFLVRRKTR 331
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
19-321 3.66e-19

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 86.30  E-value: 3.66e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  19 IATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSII-DLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSG 97
Cdd:PRK10440  20 VAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVtEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTG 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381  98 ALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLEILTQNPLMKIP----- 172
Cdd:PRK10440 100 AWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAFNTWLLLKASLETAltagl 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229890381 173 ------QGLTmkiWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQL 246
Cdd:PRK10440 180 wnagslNGLT---WAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLVAVVLTAAATALAGPI 256

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 229890381 247 AFLGIIVPHVVRKLVGGNyRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNR 321
Cdd:PRK10440 257 SFIALVAPHIARRLSGTA-RWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK 330
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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