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Conserved domains on  [gi|229562102|gb|ACQ78164|]
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putative Rep protein [Circovirus-like genome RW-E]

Protein Classification

P-loop NTPase family protein( domain architecture ID 1562424)

P-loop NTPase (nucleoside triphosphate hydrolase) family protein contains two conserved sequence signatures, the Walker A motif (the P-loop proper) and Walker B motif which bind, respectively, the beta and gamma phosphate moieties of the bound nucleotide (typically ATP or GTP), and a Mg(2+) cation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNA_helicase super family cl46641
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 155-198 2.29e-08

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


The actual alignment was detected with superfamily member pfam00910:

Pssm-ID: 459992  Cd Length: 102  Bit Score: 50.68  E-value: 2.29e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 229562102  155 CGPTGTGKSRRAWAEAGMDA----------YPKDPRTKFWDGYRDQKHVVVDEF 198
Cdd:pfam00910   4 YGPPGCGKSTLAKYLARALLkklglpkdsvYSRNPDDDFWDGYTGQPVVIIDDF 57
 
Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 155-198 2.29e-08

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 50.68  E-value: 2.29e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 229562102  155 CGPTGTGKSRRAWAEAGMDA----------YPKDPRTKFWDGYRDQKHVVVDEF 198
Cdd:pfam00910   4 YGPPGCGKSTLAKYLARALLkklglpkdsvYSRNPDDDFWDGYTGQPVVIIDDF 57
 
Name Accession Description Interval E-value
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 155-198 2.29e-08

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 50.68  E-value: 2.29e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 229562102  155 CGPTGTGKSRRAWAEAGMDA----------YPKDPRTKFWDGYRDQKHVVVDEF 198
Cdd:pfam00910   4 YGPPGCGKSTLAKYLARALLkklglpkdsvYSRNPDDDFWDGYTGQPVVIIDDF 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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