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Conserved domains on  [gi|228833385|gb|EEM78948|]
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Stage 0 sporulation regulatory protein [Bacillus thuringiensis serovar pondicheriensis BGSC 4BA1]

Protein Classification

aspartyl-phosphate phosphatase Spo0E family protein( domain architecture ID 10559368)

aspartyl-phosphate phosphatase Spo0E specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SpoOE-like pfam09388
Spo0E like sporulation regulatory protein; Spore formation is an extreme response to ...
 8-44 1.33e-12

Spo0E like sporulation regulatory protein; Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.


:

Pssm-ID: 462783  Cd Length: 42  Bit Score: 55.11  E-value: 1.33e-12
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 228833385   8 EQAIEKKREKMIYFAERYGMTSQKTVDCSQELDRLLN 44
Cdd:pfam09388  2 LKEIEELRKELNELAEKKGLTDPEVVELSQELDELIN 38
 
Name Accession Description Interval E-value
SpoOE-like pfam09388
Spo0E like sporulation regulatory protein; Spore formation is an extreme response to ...
 8-44 1.33e-12

Spo0E like sporulation regulatory protein; Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.


Pssm-ID: 462783  Cd Length: 42  Bit Score: 55.11  E-value: 1.33e-12
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 228833385   8 EQAIEKKREKMIYFAERYGMTSQKTVDCSQELDRLLN 44
Cdd:pfam09388  2 LKEIEELRKELNELAEKKGLTDPEVVELSQELDELIN 38
Spo0E COG5804
Stage 0 sporulation regulatory phosphatase Spo0E [Cell cycle control, cell division, ...
 8-44 5.12e-11

Stage 0 sporulation regulatory phosphatase Spo0E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 444506  Cd Length: 55  Bit Score: 51.76  E-value: 5.12e-11
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 228833385  8 EQAIEKKREKMIYFAERYGMTSQKTVDCSQELDRLLN 44
Cdd:COG5804   9 LKKIEELREELNELAEEKGLTDPEVLELSQELDKLLN 45
 
Name Accession Description Interval E-value
SpoOE-like pfam09388
Spo0E like sporulation regulatory protein; Spore formation is an extreme response to ...
 8-44 1.33e-12

Spo0E like sporulation regulatory protein; Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.


Pssm-ID: 462783  Cd Length: 42  Bit Score: 55.11  E-value: 1.33e-12
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 228833385   8 EQAIEKKREKMIYFAERYGMTSQKTVDCSQELDRLLN 44
Cdd:pfam09388  2 LKEIEELRKELNELAEKKGLTDPEVVELSQELDELIN 38
Spo0E COG5804
Stage 0 sporulation regulatory phosphatase Spo0E [Cell cycle control, cell division, ...
 8-44 5.12e-11

Stage 0 sporulation regulatory phosphatase Spo0E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 444506  Cd Length: 55  Bit Score: 51.76  E-value: 5.12e-11
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 228833385  8 EQAIEKKREKMIYFAERYGMTSQKTVDCSQELDRLLN 44
Cdd:COG5804   9 LKKIEELREELNELAEEKGLTDPEVLELSQELDKLLN 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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