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Conserved domains on  [gi|225543306|ref|NP_796358|]
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tetratricopeptide repeat protein 16 isoform a [Mus musculus]

Protein Classification

TPR and NlpI domain-containing protein( domain architecture ID 12778898)

TPR and NlpI domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
292-474 1.16e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.44  E-value: 1.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 292 IENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMvtdtqdnlvkqaQRQLLLTYNDFAVHCYNHGAYQEGVLLLNKA 371
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL------------DPDDAEALYNLGLAYLRLGRYEEALADYEQA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 372 IRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSP 451
Cdd:COG0457   69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG-------RYDEAIEAYERALELDP 141

                        170       180
                 ....*....|....*....|...
gi 225543306 452 QKPQYYLHRAKCRQFLQNTLGAR 474
Cdd:COG0457  142 DDADALYNLGIALEKLGRYEEAL 164
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
72-272 2.89e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.20  E-value: 2.89e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  72 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 151
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 152 VLYLQGqclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNF- 230
Cdd:COG0457   85 ALQALG-------RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKl 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 225543306 231 --FQKAKLCYQDLRSALLLDPLHAQAKGLLQKMVDQAKQSLQDA 272
Cdd:COG0457  158 grYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLL 201
NlpI super family cl34822
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
394-569 2.40e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


The actual alignment was detected with superfamily member COG4785:

Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.37  E-value: 2.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 394 NLAFAEADYKQALALSPLDEGANLRM-GVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLG 472
Cdd:COG4785   53 LAAAALAAERIDRALALPDLAQLYYErGVAYDSLG-------DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 473 ARLDVATVLLLNPEYPkmAAVMN---TLFpsmtvenvlKSQVAELAKLQLSRMIENGPKNiyPQSTVVQRLLERRKA--- 546
Cdd:COG4785  126 ALEDFDRALELDPDYA--YAYLNrgiALY---------YLGRYELAIADLEKALELDPND--PERALWLYLAERKLDpek 192

                        170       180
                 ....*....|....*....|....*..
gi 225543306 547 --QVLVKLWK--QERLGTPEEEVTLYQ 569
Cdd:COG4785  193 alALLLEDWAtaYLLQGDTEEARELFK 219
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
292-474 1.16e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.44  E-value: 1.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 292 IENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMvtdtqdnlvkqaQRQLLLTYNDFAVHCYNHGAYQEGVLLLNKA 371
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL------------DPDDAEALYNLGLAYLRLGRYEEALADYEQA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 372 IRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSP 451
Cdd:COG0457   69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG-------RYDEAIEAYERALELDP 141

                        170       180
                 ....*....|....*....|...
gi 225543306 452 QKPQYYLHRAKCRQFLQNTLGAR 474
Cdd:COG0457  142 DDADALYNLGIALEKLGRYEEAL 164
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
72-272 2.89e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.20  E-value: 2.89e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  72 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 151
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 152 VLYLQGqclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNF- 230
Cdd:COG0457   85 ALQALG-------RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKl 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 225543306 231 --FQKAKLCYQDLRSALLLDPLHAQAKGLLQKMVDQAKQSLQDA 272
Cdd:COG0457  158 grYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLL 201
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 73-457 1.96e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 64.23  E-value: 1.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306   73 AKVREyynQGHQCLLQEDWEMSVLFFSRALHLDPKLVdFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFV 152
Cdd:TIGR00990 128 AKLKE---KGNKAYRNKDFNKAIKLYSKAIECKPDPV-YYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANA 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  153 LYLQGQCLYELCDFQeALCVflqasdlqpqNASFSYRCMACLLA--LKRYHDCLALITREVKQGRASADVYIlrarlYNF 230
Cdd:TIGR00990 204 YDGLGKYADALLDLT-ASCI----------IDGFRNEQSAQAVErlLKKFAESKAKEILETKPENLPSVTFV-----GNY 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  231 FQ--KAKLCYQDLRSALLLDplHAQAKGLLQK----MVDQAKQSLQDASTLAVQgkvhralkcincAIENNPLDPNFFF- 303
Cdd:TIGR00990 268 LQsfRPKPRPAGLEDSNELD--EETGNGQLQLglksPESKADESYEEAARAFEK------------ALDLGKLGEKEAIa 333

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  304 --FRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQLLLTYNDFAvhcYNHgayqegvllLNKAIRDEQNEKGL 381
Cdd:TIGR00990 334 lnLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKA---EED---------FDKALKLNSEDPDI 401

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 225543306  382 YINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYY 457
Cdd:TIGR00990 402 YYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEG-------SIASSMATFRRCKKNFPEAPDVY 470
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 121-207 6.15e-06

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 44.94  E-value: 6.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  121 QLCDFSSALQNLRRAYSYDPGNNKYLnrlafvlYLQGQCLYELCDFQEALCVfLQASDLQPQNASFSYRCMACLLALKRY 200
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAEPESPEDA-------YLLAQCLFLNGQYKRAYEL-LRKAKLNGSSLGCRYLFAQCLLKLKKY 72


                  ....*..
gi 225543306  201 HDCLALI 207
Cdd:pfam12895  73 DEALDAL 79
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 81-186 3.63e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 46.70  E-value: 3.63e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  81 QGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNK-YLNrlafvlylQGQC 159
Cdd:PLN03088   8 KAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKaYLR--------KGTA 79

                         90       100
                 ....*....|....*....|....*..
gi 225543306 160 LYELCDFQEALCVFLQASDLQPQNASF 186
Cdd:PLN03088  80 CMKLEEYQTAKAALEKGASLAPGDSRF 106
TPR_1 pfam00515
Tetratricopeptide repeat;
382-410 9.93e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.10  E-value: 9.93e-05
                          10        20
                  ....*....|....*....|....*....
gi 225543306  382 YINRGDCFFQLGNLAFAEADYKQALALSP 410
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNP 32
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
394-569 2.40e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.37  E-value: 2.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 394 NLAFAEADYKQALALSPLDEGANLRM-GVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLG 472
Cdd:COG4785   53 LAAAALAAERIDRALALPDLAQLYYErGVAYDSLG-------DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 473 ARLDVATVLLLNPEYPkmAAVMN---TLFpsmtvenvlKSQVAELAKLQLSRMIENGPKNiyPQSTVVQRLLERRKA--- 546
Cdd:COG4785  126 ALEDFDRALELDPDYA--YAYLNrgiALY---------YLGRYELAIADLEKALELDPND--PERALWLYLAERKLDpek 192

                        170       180
                 ....*....|....*....|....*..
gi 225543306 547 --QVLVKLWK--QERLGTPEEEVTLYQ 569
Cdd:COG4785  193 alALLLEDWAtaYLLQGDTEEARELFK 219
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 115-181 4.09e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 43.39  E-value: 4.09e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 225543306 115 RAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLafvlylqGQCLYELCDFQEALCVFLQASDLQP 181
Cdd:cd24142    6 KAEELLDQGNFELALKFLQRALELEPNNVEALELL-------GEILLELGDVEEAREVLLRAIELDP 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 88-525 4.15e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.92  E-value: 4.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306   88 QEDWEMSVLFFSRALHLDPKLVdfYVFRAEAFIQLC--DFSSALQNLRRAYSYDPGNNKYLNrlafvlyLQGQCLYELCD 165
Cdd:TIGR02917 308 LGNLEQAYQYLNQILKYAPNSH--QARRLLASIQLRlgRVDEAIATLSPALGLDPDDPAALS-------LLGEAYLALGD 378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  166 FQEALCVFLQASDLQPQNASFSYRcmaclLALKRyhdclaLITREVKQGRAsadvyilrarlyNFFQKAKLCYQDLRSAL 245
Cdd:TIGR02917 379 FEKAAEYLAKATELDPENAAARTQ-----LGISK------LSQGDPSEAIA------------DLETAAQLDPELGRADL 435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  246 LL----------DPLHAQAKGLLQKMVDQAKQSLQDASTLAVQGKVHRALKCINCAIEnnpLDPNFFFFRGTLRRRLQQF 315
Cdd:TIGR02917 436 LLilsylrsgqfDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALS---IEPDFFPAAANLARIDIQE 512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  316 DHAVEDFLKAMDMVTDTQDNLvkqaqrQLLLTYNDFAVHcynHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNL 395
Cdd:TIGR02917 513 GNPDDAIQRFEKVLTIDPKNL------RAILALAGLYLR---TGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQL 583

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  396 AFAEADYKQALALSPlDEGANLRMgvlqekLGFCQQKHRQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARl 475
Cdd:TIGR02917 584 KKALAILNEAADAAP-DSPEAWLM------LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAI- 655

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 225543306  476 dvatvlllnpEYPKMAAvmnTLFPSMTVENVLKSQVAELAK-----LQLSRMIEN 525
Cdd:TIGR02917 656 ----------TSLKRAL---ELKPDNTEAQIGLAQLLLAAKrtesaKKIAKSLQK 697
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 367-456 5.85e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 42.85  E-value: 5.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 367 LLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEA 446
Cdd:PLN03088  24 LYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLE-------EYQTAKAALEKG 96

                         90
                 ....*....|
gi 225543306 447 IRHSPQKPQY 456
Cdd:PLN03088  97 ASLAPGDSRF 106
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 382-410 9.26e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 9.26e-04
                           10        20
                   ....*....|....*....|....*....
gi 225543306   382 YINRGDCFFQLGNLAFAEADYKQALALSP 410
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDP 32
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
292-474 1.16e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 80.44  E-value: 1.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 292 IENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMvtdtqdnlvkqaQRQLLLTYNDFAVHCYNHGAYQEGVLLLNKA 371
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL------------DPDDAEALYNLGLAYLRLGRYEEALADYEQA 68

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 372 IRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSP 451
Cdd:COG0457   69 LELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG-------RYDEAIEAYERALELDP 141

                        170       180
                 ....*....|....*....|...
gi 225543306 452 QKPQYYLHRAKCRQFLQNTLGAR 474
Cdd:COG0457  142 DDADALYNLGIALEKLGRYEEAL 164
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
72-272 2.89e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.20  E-value: 2.89e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  72 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 151
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 152 VLYLQGqclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNF- 230
Cdd:COG0457   85 ALQALG-------RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKl 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 225543306 231 --FQKAKLCYQDLRSALLLDPLHAQAKGLLQKMVDQAKQSLQDA 272
Cdd:COG0457  158 grYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLL 201
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 352-487 3.05e-15

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 73.30  E-value: 3.05e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 352 AVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqq 431
Cdd:COG4783   11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAG---- 86

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 225543306 432 khrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNPEY 487
Cdd:COG4783   87 ---DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
272-461 3.49e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.20  E-value: 3.49e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 272 ASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMvtdtqdnlvkqaQRQLLLTYNDF 351
Cdd:COG0457   15 GLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL------------DPDDAEALNNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 352 AVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGFCQQ 431
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEE 162

                        170       180       190
                 ....*....|....*....|....*....|
gi 225543306 432 KHRQFQTAEEHFSEAIRHSPQKPQYYLHRA 461
Cdd:COG0457  163 ALELLEKLEAAALAALLAAALGEAALALAA 192
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 78-327 4.03e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 76.31  E-value: 4.03e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  78 YYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQG 157
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 158 qclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLC 237
Cdd:COG2956   91 -------LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEA 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 238 YQDLRSALLLDPLHAQAKGLLqkmvdqakqslqdASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDH 317
Cdd:COG2956  164 IEALEKALKLDPDCARALLLL-------------AELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEE 230

                        250
                 ....*....|
gi 225543306 318 AVEDFLKAMD 327
Cdd:COG2956  231 ALELLRKALE 240
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
347-488 4.29e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.81  E-value: 4.29e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 347 TYNDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKL 426
Cdd:COG0457   10 AYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQAL 89

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 225543306 427 GfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNPEYP 488
Cdd:COG0457   90 G-------RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDA 144
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
102-352 3.01e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.12  E-value: 3.01e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 102 LHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALCVFLQASDLQP 181
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLG-------RYEEALADYEQALELDP 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 182 QNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLY---NFFQKAKLCYQDlrsALLLDPLHAQAKGLL 258
Cdd:COG0457   74 DDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALlelGRYDEAIEAYER---ALELDPDDADALYNL 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 259 QKMVDQAKQSLQDASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVK 338
Cdd:COG0457  151 GIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALL 230

                        250
                 ....*....|....
gi 225543306 339 QAQRQLLLTYNDFA 352
Cdd:COG0457  231 LALRLAALALYQYR 244
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 251-493 1.41e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.68  E-value: 1.41e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 251 HAQAKGLLQKMVDQAKQSLQDASTLAV----QGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAM 326
Cdd:COG2956   24 PDKAIDLLEEALELDPETVEAHLALGNlyrrRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 327 DMVTDTQDnlvkqAQRQLLLTYNDfavhcynHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQAL 406
Cdd:COG2956  104 ELDPDDAE-----ALRLLAEIYEQ-------EGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 407 ALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNPE 486
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQG-------DYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPS 244


                 ....*..
gi 225543306 487 YPKMAAV 493
Cdd:COG2956  245 DDLLLAL 251
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
78-259 1.92e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 70.81  E-value: 1.92e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  78 YYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQG 157
Cdd:COG0457   45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELG 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 158 qclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLC 237
Cdd:COG0457  125 -------RYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLL 197

                        170       180
                 ....*....|....*....|..
gi 225543306 238 YQDLRSALLLDPLHAQAKGLLQ 259
Cdd:COG0457  198 ALLLALEQALRKKLAILTLAAL 219
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 189-468 1.38e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.18  E-value: 1.38e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 189 RCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKGLLQkmvDQAKQS 268
Cdd:COG3914    5 ALLALAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALL---LLAALL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 269 LQDASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMVTDtqdnlvkqaqrqLLLTY 348
Cdd:COG3914   82 ELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPD------------FAEAY 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 349 NDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGF 428
Cdd:COG3914  150 LNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACD 229

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 225543306 429 CQQKHRQFQTAEEHFSEAIRHSPQKPQYY------LHRAKCRQFLQ 468
Cdd:COG3914  230 WEVYDRFEELLAALARGPSELSPFALLYLpdddpaELLALARAWAQ 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
382-489 3.46e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.34  E-value: 3.46e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 382 YINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRA 461
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLG-------RYEEALADYEQALELDPDDAEALNNLG 83

                         90       100
                 ....*....|....*....|....*...
gi 225543306 462 KCRQFLQNTLGARLDVATVLLLNPEYPK 489
Cdd:COG0457   84 LALQALGRYEEALEDYDKALELDPDDAE 111
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 264-410 4.51e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 64.06  E-value: 4.51e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 264 QAKQSLQDASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMdmvtdtqdnlvkQAQRQ 343
Cdd:COG4783    3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEAL------------ELDPD 70

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 225543306 344 LLLTYNDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSP 410
Cdd:COG4783   71 EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 72-195 8.27e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.87  E-value: 8.27e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  72 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 151
Cdd:COG3914  109 PDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGN 188

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 225543306 152 VLYLQGQclyelcdFQEALCVFLQASDLQPQNASFSYRCMACLL 195
Cdd:COG3914  189 ALQDLGR-------LEEAIAAYRRALELDPDNADAHSNLLFALR 225
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 73-213 1.78e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.52  E-value: 1.78e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  73 AKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFV 152
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 225543306 153 LYLQGqclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQ 213
Cdd:COG4783   82 LLKAG-------DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 77-258 1.83e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 64.63  E-value: 1.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  77 EYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQ 156
Cdd:COG3914   46 LLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLAL 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 157 GQclyelcdFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLY---NFFQK 233
Cdd:COG3914  126 GR-------LEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALqdlGRLEE 198

                        170       180
                 ....*....|....*....|....*
gi 225543306 234 AKLCYqdlRSALLLDPLHAQAKGLL 258
Cdd:COG3914  199 AIAAY---RRALELDPDNADAHSNL 220
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 73-457 1.96e-10

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 64.23  E-value: 1.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306   73 AKVREyynQGHQCLLQEDWEMSVLFFSRALHLDPKLVdFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFV 152
Cdd:TIGR00990 128 AKLKE---KGNKAYRNKDFNKAIKLYSKAIECKPDPV-YYSNRAACHNALGDWEKVVEDTTAALELDPDYSKALNRRANA 203

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  153 LYLQGQCLYELCDFQeALCVflqasdlqpqNASFSYRCMACLLA--LKRYHDCLALITREVKQGRASADVYIlrarlYNF 230
Cdd:TIGR00990 204 YDGLGKYADALLDLT-ASCI----------IDGFRNEQSAQAVErlLKKFAESKAKEILETKPENLPSVTFV-----GNY 267

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  231 FQ--KAKLCYQDLRSALLLDplHAQAKGLLQK----MVDQAKQSLQDASTLAVQgkvhralkcincAIENNPLDPNFFF- 303
Cdd:TIGR00990 268 LQsfRPKPRPAGLEDSNELD--EETGNGQLQLglksPESKADESYEEAARAFEK------------ALDLGKLGEKEAIa 333

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  304 --FRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQLLLTYNDFAvhcYNHgayqegvllLNKAIRDEQNEKGL 381
Cdd:TIGR00990 334 lnLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGDPDKA---EED---------FDKALKLNSEDPDI 401

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 225543306  382 YINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYY 457
Cdd:TIGR00990 402 YYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEG-------SIASSMATFRRCKKNFPEAPDVY 470
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
78-248 3.87e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.18  E-value: 3.87e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  78 YYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQG 157
Cdd:COG0457   79 LNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 158 qclyelcDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLC 237
Cdd:COG0457  159 -------RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLL 231

                        170
                 ....*....|.
gi 225543306 238 YQDLRSALLLD 248
Cdd:COG0457  232 ALRLAALALYQ 242
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
72-184 5.41e-10

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 60.31  E-value: 5.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  72 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNK-YLNRla 150
Cdd:COG4785   70 PDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYaYLNR-- 147

                         90       100       110
                 ....*....|....*....|....*....|....
gi 225543306 151 fvlylqGQCLYELCDFQEALCVFLQASDLQPQNA 184
Cdd:COG4785  148 ------GIALYYLGRYELAIADLEKALELDPNDP 175
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
240-467 5.94e-10

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 60.31  E-value: 5.94e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 240 DLRSALLLDPLHAQAKGLLQKMVDQAKQSLQDASTLAVQGKVHRALK-----CINCAIEN--------NPLDPNFFFFRG 306
Cdd:COG4785    1 LYALALALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALAlaaaaLAAAALAAeridralaLPDLAQLYYERG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 307 TLRRRLQQFDHAVEDFlkamdmvtdtqdnlvkqaqrqllltyndfavhcynhgayqegvlllNKAIRDEQNEKGLYINRG 386
Cdd:COG4785   81 VAYDSLGDYDLAIADF----------------------------------------------DQALELDPDLAEAYNNRG 114

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 387 DCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQF 466
Cdd:COG4785  115 LAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLG-------RYELAIADLEKALELDPNDPERALWLYLAERK 187


                 .
gi 225543306 467 L 467
Cdd:COG4785  188 L 188
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 86-245 6.56e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 60.90  E-value: 6.56e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  86 LLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcD 165
Cdd:COG2956  121 EQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQG-------D 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 166 FQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALItREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSAL 245
Cdd:COG2956  194 YEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELL-RKALELDPSDDLLLALADLLERKEGLEAALALLERQL 272
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 115-249 8.38e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 57.89  E-value: 8.38e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 115 RAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALCVFLQASDLQPQNASFSYRCMACL 194
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLG-------DLDEAIVLLHEALELDPDEPEARLNLGLAL 82

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 225543306 195 LALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDP 249
Cdd:COG4783   83 LKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 76-267 1.49e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 61.55  E-value: 1.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  76 REYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYL 155
Cdd:COG3914   79 ALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRR 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 156 QGQclyelcdFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITR--EVKQGRASADVYILRARL------ 227
Cdd:COG3914  159 LGR-------LEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRalELDPDNADAHSNLLFALRqacdwe 231

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 225543306 228 -YNFFQKAKLCYQDLRSALLLDPLHAQAKGLLQKMVDQAKQ 267
Cdd:COG3914  232 vYDRFEELLAALARGPSELSPFALLYLPDDDPAELLALARA 272
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 72-184 1.64e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.55  E-value: 1.64e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  72 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 151
Cdd:COG4235   14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGL 93

                         90       100       110
                 ....*....|....*....|....*....|...
gi 225543306 152 VLYLQGqclyelcDFQEALCVFLQASDLQPQNA 184
Cdd:COG4235   94 AAFQQG-------DYAEAIAAWQKLLALLPADA 119
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 86-181 1.82e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 57.28  E-value: 1.82e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  86 LLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcD 165
Cdd:COG5010   65 NKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLG-------Q 137

                         90
                 ....*....|....*.
gi 225543306 166 FQEALCVFLQASDLQP 181
Cdd:COG5010  138 DDEAKAALQRALGTSP 153
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 100-227 1.91e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.55  E-value: 1.91e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 100 RALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALCVFLQASDL 179
Cdd:COG4235    8 QALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAG-------DTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 225543306 180 QPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARL 227
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 360-485 3.14e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 56.51  E-value: 3.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 360 AYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTA 439
Cdd:COG5010   35 NNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSG-------DKDEA 107

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 225543306 440 EEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNP 485
Cdd:COG5010  108 KEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 98-272 5.75e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 5.75e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  98 FSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALCVFLQAS 177
Cdd:COG2956   99 LEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQG-------DYDEAIEALEKAL 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 178 DLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKGL 257
Cdd:COG2956  172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLAL 251

                        170       180
                 ....*....|....*....|
gi 225543306 258 L-----QKMVDQAKQSLQDA 272
Cdd:COG2956  252 AdllerKEGLEAALALLERQ 271
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 308-451 1.47e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.58  E-value: 1.47e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 308 LRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQLLLTYNDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYINRGD 387
Cdd:COG5010   17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLAL 96

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 225543306 388 CFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSP 451
Cdd:COG5010   97 LYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLG-------QDDEAKAALQRALGTSP 153
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 72-213 1.61e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.66  E-value: 1.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  72 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAf 151
Cdd:COG2956  141 PENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLA- 219

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 225543306 152 vlylqgQCLYELCDFQEALCVFLQASDLQPQNASFSYRCMAcLLALKRYHDCLALITREVKQ 213
Cdd:COG2956  220 ------ELYEKLGDPEEALELLRKALELDPSDDLLLALADL-LERKEGLEAALALLERQLRR 274
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
388-486 4.71e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 51.32  E-value: 4.71e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 388 CFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEhFSEAIRHSPQKPQYYLHRAKCRQFL 467
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQG-------RYDEAIA-LEKALKLDPNNAEALLNLAELLLEL 72

                         90
                 ....*....|....*....
gi 225543306 468 QNTLGARLDVATVLLLNPE 486
Cdd:COG3063   73 GDYDEALAYLERALELDPS 91
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 283-413 6.76e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.93  E-value: 6.76e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 283 RALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQllltyndfavhcYNHGAYQ 362
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEAL------------LAAGDTE 68

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 225543306 363 EGVLLLNKAIR-DEQNEKGLYiNRGDCFFQLGNLAFAEADYKQALALSPLDE 413
Cdd:COG4235   69 EAEELLERALAlDPDNPEALY-LLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 81-325 1.13e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.47  E-value: 1.13e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306   81 QGHQCLLQEDWEMSVLFFSRALHLDPKLVdfYVFRAEAFIQLC--DFSSALQNLRRAYSYDPGNNKYLNrlafvlyLQGQ 158
Cdd:TIGR02917 131 RGLAYLGLGQLELAQKSYEQALAIDPRSL--YAKLGLAQLALAenRFDEARALIDEVLTADPGNVDALL-------LKGD 201

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  159 CLYELCDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYnfFQKAKlcY 238
Cdd:TIGR02917 202 LLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVD--FQKKN--Y 277

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  239 QDLRS----ALLLDP-----------------LHAQAKGLLQKMVDQAKQSLQD----ASTLAVQGKVHRALKCINCAIE 293
Cdd:TIGR02917 278 EDAREtlqdALKSAPeylpalllagaseyqlgNLEQAYQYLNQILKYAPNSHQArrllASIQLRLGRVDEAIATLSPALG 357

                         250       260       270
                  ....*....|....*....|....*....|..
gi 225543306  294 NNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKA 325
Cdd:TIGR02917 358 LDPDDPAALSLLGEAYLALGDFEKAAEYLAKA 389
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 77-441 1.37e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.47  E-value: 1.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306   77 EYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQ 156
Cdd:TIGR02917  24 ELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYLLQ 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  157 GQclyelcdFQEALCVFLQASDLQPQNAS--FSYRCMAcLLALKRYHDCLALITREVKQGRASADVYILRARL---YNFF 231
Cdd:TIGR02917 104 GK-------FQQVLDELPGKTLLDDEGAAelLALRGLA-YLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLalaENRF 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  232 QKAKlcyQDLRSALLLDPLHAQAKGLLqkmvdqakqslqdASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGTLRRR 311
Cdd:TIGR02917 176 DEAR---ALIDEVLTADPGNVDALLLK-------------GDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIE 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  312 LQQFDHAVEDFlkamdmvtdtqDNLVKQAQRQLLLTYNDFAVHcYNHGAYQEGVLLLNKAIR-DEQNEKGLYInRGDCFF 390
Cdd:TIGR02917 240 AGEFEEAEKHA-----------DALLKKAPNSPLAHYLKALVD-FQKKNYEDARETLQDALKsAPEYLPALLL-AGASEY 306

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|.
gi 225543306  391 QLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGFCQQKHRQFQTAEE 441
Cdd:TIGR02917 307 QLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALG 357
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 305-488 1.68e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.00  E-value: 1.68e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 305 RGTLRRRLQQFDHAVEDFLKAMDMVTDTQDNLVKQAQRQLLLTYNDFAvHCYNHGAYQEGVLLLNKAIRDEQNEKglyin 384
Cdd:COG3914   14 AAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLA-LAAGEAAAAAAALLLLAALLELAALL----- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 385 rgdcFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCR 464
Cdd:COG3914   88 ----LQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALG-------RLEEALAALRRALALNPDFAEAYLNLGEAL 156

                        170       180
                 ....*....|....*....|....
gi 225543306 465 QFLQNTLGARLDVATVLLLNPEYP 488
Cdd:COG3914  157 RRLGRLEEAIAALRRALELDPDNA 180
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
103-270 1.79e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 52.61  E-value: 1.79e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 103 HLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALCVFLQASDLQPQ 182
Cdd:COG4785   67 LALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLG-------DYDAALEDFDRALELDPD 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 183 NA-SFSYRCMAcLLALKRYHDCLALITREVKQGRASADVYILRarlynFFQKAKLCYQDLRSALLLDPL-HAQAKGLLQK 260
Cdd:COG4785  140 YAyAYLNRGIA-LYYLGRYELAIADLEKALELDPNDPERALWL-----YLAERKLDPEKALALLLEDWAtAYLLQGDTEE 213

                        170
                 ....*....|
gi 225543306 261 MVDQAKQSLQ 270
Cdd:COG4785  214 ARELFKLALA 223
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
86-181 2.33e-07

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 49.40  E-value: 2.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  86 LLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQnLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcD 165
Cdd:COG3063    3 LKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELG-------D 74

                         90
                 ....*....|....*.
gi 225543306 166 FQEALCVFLQASDLQP 181
Cdd:COG3063   75 YDEALAYLERALELDP 90
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 356-461 7.69e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 7.69e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 356 YNHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQ 435
Cdd:COG4235   28 LRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQG-------D 100

                         90       100
                 ....*....|....*....|....*.
gi 225543306 436 FQTAEEHFSEAIRHSPQKPQYYLHRA 461
Cdd:COG4235  101 YAEAIAAWQKLLALLPADAPARLLEA 126
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 363-493 8.07e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.85  E-value: 8.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 363 EGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEH 442
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAG-------DTEEAEEL 73

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 225543306 443 FSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARLDVATVLLLNPEYPKMAAV 493
Cdd:COG4235   74 LERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLL 124
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 78-183 1.32e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.65  E-value: 1.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  78 YYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQG 157
Cdd:COG4783   41 FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALG 120

                         90       100
                 ....*....|....*....|....*.
gi 225543306 158 QclyelcdFQEALCVFLQASDLQPQN 183
Cdd:COG4783  121 R-------PDEAIAALEKALELDPDD 139
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 72-188 2.03e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.53  E-value: 2.03e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  72 PAKVREYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAF 151
Cdd:COG3914  143 PDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLF 222

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 225543306 152 VLYlqGQCLYELCDFQEALCVFLQASDLQPQNASFSY 188
Cdd:COG3914  223 ALR--QACDWEVYDRFEELLAALARGPSELSPFALLY 257
ANAPC3 pfam12895
Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of ...
 121-207 6.15e-06

Anaphase-promoting complex, cyclosome, subunit 3; Apc3, otherwise known as Cdc27, is one of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes. The protein members of this family contain TPR repeats just as those of Apc7 do, and it appears that these TPR units bind the C-termini of the APC co-activators CDH1 and CDC20.


Pssm-ID: 463743 [Multi-domain]  Cd Length: 82  Bit Score: 44.94  E-value: 6.15e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  121 QLCDFSSALQNLRRAYSYDPGNNKYLnrlafvlYLQGQCLYELCDFQEALCVfLQASDLQPQNASFSYRCMACLLALKRY 200
Cdd:pfam12895   1 DQHQYKNAIFLAERLLAAEPESPEDA-------YLLAQCLFLNGQYKRAYEL-LRKAKLNGSSLGCRYLFAQCLLKLKKY 72


                  ....*..
gi 225543306  201 HDCLALI 207
Cdd:pfam12895  73 DEALDAL 79
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 99-286 1.55e-05

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 48.44  E-value: 1.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306   99 SRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKylnrlafVLYLQGQCLYELCDFQEALCVFLQASD 178
Cdd:TIGR00990 355 SKSIELDPRVTQSYIKRASMNLELGDPDKAEEDFDKALKLNSEDPD-------IYYHRAQLHFIKGEFAQAGKDYQKSID 427

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  179 LQPQNAsFSYRCMACL-LALKRYHDCLALITREVKQGRASADVYILRARLY---NFFQKAKLCYqDLRSAL--LLDPLH- 251
Cdd:TIGR00990 428 LDPDFI-FSHIQLGVTqYKEGSIASSMATFRRCKKNFPEAPDVYNYYGELLldqNKFDEAIEKF-DTAIELekETKPMYm 505

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  252 -------------------AQAKGLLQKMV------DQAKQSLqdASTLAVQGKVHRALK 286
Cdd:TIGR00990 506 nvlplinkalalfqwkqdfIEAENLCEKALiidpecDIAVATM--AQLLLQQGDVDEALK 563
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 204-340 1.70e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.00  E-value: 1.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 204 LALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKGLLqkmvdqakqslqdASTLAVQGKVHR 283
Cdd:COG4235    3 IARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL-------------AEALLAAGDTEE 69

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 225543306 284 ALKCINCAIENNPLDPNFFFFRGTLRRRLQQFDHAVEDFLKAMDMV-TDTQDNLVKQA 340
Cdd:COG4235   70 AEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLpADAPARLLEAS 127
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 81-186 3.63e-05

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 46.70  E-value: 3.63e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  81 QGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNK-YLNrlafvlylQGQC 159
Cdd:PLN03088   8 KAKEAFVDDDFALAVDLYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKaYLR--------KGTA 79

                         90       100
                 ....*....|....*....|....*..
gi 225543306 160 LYELCDFQEALCVFLQASDLQPQNASF 186
Cdd:PLN03088  80 CMKLEEYQTAKAALEKGASLAPGDSRF 106
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
359-451 4.15e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.85  E-value: 4.15e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 359 GAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEAdYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQT 438
Cdd:COG3063    6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELG-------DYDE 77

                         90
                 ....*....|...
gi 225543306 439 AEEHFSEAIRHSP 451
Cdd:COG3063   78 ALAYLERALELDP 90
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 98-250 7.27e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 7.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  98 FSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGQCLYELCDFQEALCVFLQAS 177
Cdd:COG5010    2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 225543306 178 DLQPQNASFSYRCMACLLALKRYHDCLALITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPL 250
Cdd:COG5010   82 QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSPL 154
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 304-411 7.41e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 7.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 304 FRGTLRRRLQQFDHAVEDFLKAMDMVTDTQDnlvkqaqrqlllTYNDFAVHCYNHGAYQEGVLLLNKAIRDEQNEKGLYI 383
Cdd:COG5010   59 PSDNLYNKLGDFEESLALLEQALQLDPNNPE------------LYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYS 126

                         90       100
                 ....*....|....*....|....*...
gi 225543306 384 NRGDCFFQLGNLAFAEADYKQALALSPL 411
Cdd:COG5010  127 NLAALLLSLGQDDEAKAALQRALGTSPL 154
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 148-326 9.62e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.26  E-value: 9.62e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 148 RLAFVLYLQGQCLYELCDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYhdclalitrevkqgrasadvyilrarl 227
Cdd:COG4783    2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDL--------------------------- 54

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 228 ynffQKAklcYQDLRSALLLDPLHAQAKGLLqkmvdqakqslqdASTLAVQGKVHRALKCINCAIENNPLDPNFFFFRGT 307
Cdd:COG4783   55 ----DEA---IVLLHEALELDPDEPEARLNL-------------GLALLKAGDYDEALALLEKALKLDPEHPEAYLRLAR 114

                        170
                 ....*....|....*....
gi 225543306 308 LRRRLQQFDHAVEDFLKAM 326
Cdd:COG4783  115 AYRALGRPDEAIAALEKAL 133
TPR_1 pfam00515
Tetratricopeptide repeat;
382-410 9.93e-05

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 40.10  E-value: 9.93e-05
                          10        20
                  ....*....|....*....|....*....
gi 225543306  382 YINRGDCFFQLGNLAFAEADYKQALALSP 410
Cdd:pfam00515   4 LYNLGNAYFKLGKYDEALEYYEKALELNP 32
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
394-569 2.40e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.37  E-value: 2.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 394 NLAFAEADYKQALALSPLDEGANLRM-GVLQEKLGfcqqkhrQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLG 472
Cdd:COG4785   53 LAAAALAAERIDRALALPDLAQLYYErGVAYDSLG-------DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 473 ARLDVATVLLLNPEYPkmAAVMN---TLFpsmtvenvlKSQVAELAKLQLSRMIENGPKNiyPQSTVVQRLLERRKA--- 546
Cdd:COG4785  126 ALEDFDRALELDPDYA--YAYLNrgiALY---------YLGRYELAIADLEKALELDPND--PERALWLYLAERKLDpek 192

                        170       180
                 ....*....|....*....|....*..
gi 225543306 547 --QVLVKLWK--QERLGTPEEEVTLYQ 569
Cdd:COG4785  193 alALLLEDWAtaYLLQGDTEEARELFK 219
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
308-410 2.57e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 2.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 308 LRRRLQQFDHAVEDFLKAMdmvtdtqdnlvkQAQRQLLLTYNDFAVHCYNHGAYQEGvLLLNKAIRDEQNEKGLYINRGD 387
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKAL------------ELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAE 67

                         90       100
                 ....*....|....*....|...
gi 225543306 388 CFFQLGNLAFAEADYKQALALSP 410
Cdd:COG3063   68 LLLELGDYDEALAYLERALELDP 90
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
118-209 2.92e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.54  E-value: 2.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 118 AFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcDFQEALcVFLQASDLQPQNASFSYRCMACLLAL 197
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQG-------RYDEAI-ALEKALKLDPNNAEALLNLAELLLEL 72

                         90
                 ....*....|..
gi 225543306 198 KRYHDCLALITR 209
Cdd:COG3063   73 GDYDEALAYLER 84
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 115-181 4.09e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 43.39  E-value: 4.09e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 225543306 115 RAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLafvlylqGQCLYELCDFQEALCVFLQASDLQP 181
Cdd:cd24142    6 KAEELLDQGNFELALKFLQRALELEPNNVEALELL-------GEILLELGDVEEAREVLLRAIELDP 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 88-525 4.15e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.92  E-value: 4.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306   88 QEDWEMSVLFFSRALHLDPKLVdfYVFRAEAFIQLC--DFSSALQNLRRAYSYDPGNNKYLNrlafvlyLQGQCLYELCD 165
Cdd:TIGR02917 308 LGNLEQAYQYLNQILKYAPNSH--QARRLLASIQLRlgRVDEAIATLSPALGLDPDDPAALS-------LLGEAYLALGD 378

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  166 FQEALCVFLQASDLQPQNASFSYRcmaclLALKRyhdclaLITREVKQGRAsadvyilrarlyNFFQKAKLCYQDLRSAL 245
Cdd:TIGR02917 379 FEKAAEYLAKATELDPENAAARTQ-----LGISK------LSQGDPSEAIA------------DLETAAQLDPELGRADL 435

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  246 LL----------DPLHAQAKGLLQKMVDQAKQSLQDASTLAVQGKVHRALKCINCAIEnnpLDPNFFFFRGTLRRRLQQF 315
Cdd:TIGR02917 436 LLilsylrsgqfDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALS---IEPDFFPAAANLARIDIQE 512

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  316 DHAVEDFLKAMDMVTDTQDNLvkqaqrQLLLTYNDFAVHcynHGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNL 395
Cdd:TIGR02917 513 GNPDDAIQRFEKVLTIDPKNL------RAILALAGLYLR---TGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQL 583

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  396 AFAEADYKQALALSPlDEGANLRMgvlqekLGFCQQKHRQFQTAEEHFSEAIRHSPQKPQYYLHRAKCRQFLQNTLGARl 475
Cdd:TIGR02917 584 KKALAILNEAADAAP-DSPEAWLM------LGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAI- 655

                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 225543306  476 dvatvlllnpEYPKMAAvmnTLFPSMTVENVLKSQVAELAK-----LQLSRMIEN 525
Cdd:TIGR02917 656 ----------TSLKRAL---ELKPDNTEAQIGLAQLLLAAKrtesaKKIAKSLQK 697
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
127-293 4.31e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.59  E-value: 4.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 127 SALQNLRRAYSYDPGNNKYLNRLAFVLYLQGQCLYELCDFQEALCVFLQASDLQPQNAS-FSYRCMAcLLALKRYHDCLA 205
Cdd:COG4785   50 AAALAAAALAAERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEaYNNRGLA-YLLLGDYDAALE 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 206 LITREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQA---KGLLQKMVD--QAKQSLQD--ASTLAVQ 278
Cdd:COG4785  129 DFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDPNDPERalwLYLAERKLDpeKALALLLEdwATAYLLQ 208

                        170
                 ....*....|....*
gi 225543306 279 GKVHRALKCINCAIE 293
Cdd:COG4785  209 GDTEEARELFKLALA 223
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 77-170 4.35e-04

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 43.00  E-value: 4.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  77 EYYNQGHQCLLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNN--KYlnrlafvLY 154
Cdd:cd24142    2 ELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDPDGGyeKY-------LY 74

                         90
                 ....*....|....*.
gi 225543306 155 LqGQclyeLCDFQEAL 170
Cdd:cd24142   75 L-GQ----LSGGEEAL 85
PLN03088 PLN03088
SGT1, suppressor of G2 allele of SKP1; Provisional
 367-456 5.85e-04

SGT1, suppressor of G2 allele of SKP1; Provisional


Pssm-ID: 215568 [Multi-domain]  Cd Length: 356  Bit Score: 42.85  E-value: 5.85e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 367 LLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLGfcqqkhrQFQTAEEHFSEA 446
Cdd:PLN03088  24 LYTQAIDLDPNNAELYADRAQANIKLGNFTEAVADANKAIELDPSLAKAYLRKGTACMKLE-------EYQTAKAALEKG 96

                         90
                 ....*....|
gi 225543306 447 IRHSPQKPQY 456
Cdd:PLN03088  97 ASLAPGDSRF 106
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 86-407 6.63e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 6.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306   86 LLQEDWEMSVLFFSRALHLDPKLVDFYVFRAEAFIQLCDFSSALQNLRRAYSYDPGNNKYLNRLAFVLYLQGqclyelcD 165
Cdd:TIGR02917 408 LSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKG-------D 480

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  166 FQEALCVFLQASDLQPQN--ASFSYRCMA-----CLLALKRYHDCLALITREVKQGRASADVYILRAR---LYNFFQKA- 234
Cdd:TIGR02917 481 LAKAREAFEKALSIEPDFfpAAANLARIDiqegnPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNeeeAVAWLEKAa 560

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  235 KLCYQDLRSALLLDPLH------AQAKGLLQKMVDQAKQSLQD----ASTLAVQGKVHRALKCINCAIENNPLDPNFFFF 304
Cdd:TIGR02917 561 ELNPQEIEPALALAQYYlgkgqlKKALAILNEAADAAPDSPEAwlmlGRAQLAAGDLNKAVSSFKKLLALQPDSALALLL 640

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306  305 RGTLRRRLQQFDHAVEDFLKAMDMVTDTQDnlVKQAQRQLLLTYNDFavhcynhgayqegvlllNKAIRDEQNEKGLYIN 384
Cdd:TIGR02917 641 LADAYAVMKNYAKAITSLKRALELKPDNTE--AQIGLAQLLLAAKRT-----------------ESAKKIAKSLQKQHPK 701

                         330       340
                  ....*....|....*....|...
gi 225543306  385 RGDCFFQLGNLAFAEADYKQALA 407
Cdd:TIGR02917 702 AALGFELEGDLYLRQKDYPAAIQ 724
TPR_11 pfam13414
TPR repeat;
386-427 6.88e-04

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 37.84  E-value: 6.88e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 225543306  386 GDCFFQLGNLAFAEADYKQALALSPLDEGANLRMGVLQEKLG 427
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKLG 42
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 382-410 9.26e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 9.26e-04
                           10        20
                   ....*....|....*....|....*....
gi 225543306   382 YINRGDCFFQLGNLAFAEADYKQALALSP 410
Cdd:smart00028   4 LYNLGNAYLKLGDYDEALEYYEKALELDP 32
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 128-265 1.15e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.99  E-value: 1.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 128 ALQNLRRAYSYDPGNnkylnrlAFVLYLQGQCLYELCDFQEALCVFLQASDLQPQNASFSYRCMACLLALKRYHDCLALI 207
Cdd:COG4235    2 AIARLRQALAANPND-------AEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELL 74

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 225543306 208 TREVKQGRASADVYILRARLYNFFQKAKLCYQDLRSALLLDPLHAQAKgLLQKMVDQA 265
Cdd:COG4235   75 ERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPAR-LLEASIAEA 131
TPR_12 pfam13424
Tetratricopeptide repeat;
381-448 2.22e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 37.75  E-value: 2.22e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 225543306  381 LYINRGDCFFQLGNLAFAEADYKQALAL-SPLDEGANLRMGVLQEKLGFCQQKHRQFQTAEEHFSEAIR 448
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIaRRLLGPDHPLTATTLLNLGRLYLELGRYEEALELLERALA 73
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 381-410 2.62e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 35.96  E-value: 2.62e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 225543306  381 LYINRGDCFFQLGNLAFAEADYKQALALSP 410
Cdd:pfam07719   3 ALYNLGLAYYKLGDYEEALEAYEKALELDP 32
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 356-455 5.13e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.66  E-value: 5.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 225543306 356 YNHGAYQEGVLLLNKAIRDEQNEKGL---YINRGDCFFQLGNLAFAEADYKQALAL---SPLDEGANLRMGVLQEKLGfc 429
Cdd:COG1729    4 LKAGDYDEAIAAFKAFLKRYPNSPLApdaLYWLGEAYYALGDYDEAAEAFEKLLKRypdSPKAPDALLKLGLSYLELG-- 81

                         90       100
                 ....*....|....*....|....*.
gi 225543306 430 qqkhrQFQTAEEHFSEAIRHSPQKPQ 455
Cdd:COG1729   82 -----DYDKARATLEELIKKYPDSEA 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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