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Conserved domains on  [gi|22550266|gb|AAN01596|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Taeniolethrinops praeorbitalis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475913)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-327 0e+00

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 530.92  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    1 MNPYILATLLFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  241 ALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320


                 ....*..
gi 22550266  321 LTYPLAT 327
Cdd:MTH00135 321 LTLPLAI 327
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-327 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 530.92  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    1 MNPYILATLLFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  241 ALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320


                 ....*..
gi 22550266  321 LTYPLAT 327
Cdd:MTH00135 321 LTLPLAI 327
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-266 8.26e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.45  E-value: 8.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    23 SSHWLLAWMGLEMNTLAIIPLMA-QHQHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITHPLPST----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    97 ------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLIL-STWQKLAPFALI---LQLQPSS---STLLIILGLTSTLI 163
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsLLYLPSSpfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   164 GGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFIMTFSTFLAFKL-----NDSTNINTLATSWA 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|..
gi 22550266   235 KAPALTALMPLILLSLGGLPPLTGSMPKWLIL 266
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLIL 272
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-299 7.53e-16

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 77.85  E-value: 7.53e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   4 YILatLLFGIgLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHQHPRAVEATTKYFLTqataaatllfASVTNAWL-- 80
Cdd:COG1007 105 YAL--LLFAT-LGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLL----------GALSSGFLly 171

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  81 --------TGQWEIQQITHPLPST------------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFA 140
Cdd:COG1007 172 gisllygaTGSLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFA 251

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266 141 LILQL--------QPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYF 208
Cdd:COG1007 252 ALLRLlveafpglAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYL 331

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266 209 IMTFSTF-----LAFKLNDSTNINTLATSWAKAPALTALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAAL 283
Cdd:COG1007 332 FMNLGAFavillLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVL 411

                       330
                ....*....|....*.
gi 22550266 284 SALLSLYFYLRLSYAM 299
Cdd:COG1007 412 NSVISAYYYLRVVKAM 427
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 23-299 1.47e-12

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 68.05  E-value: 1.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    23 SSHWLLAWMGLEMNTLAIIPLMA-QHQHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITHPLPSTMIT-- 99
Cdd:TIGR01770 121 SNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNGMLNis 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   100 ----------LALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSS--------STLLIILGLTST 161
Cdd:TIGR01770 201 llllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseawQIFLAIIAFLSM 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   162 LIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTY-FIMTFSTFLAF---------KLNDSTNINTLAT 231
Cdd:TIGR01770 281 LIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYiFIYALMSLGAFgvlsllrsyKDEWIEYISDFAG 360

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22550266   232 SWAKAPALTALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAM 299
Cdd:TIGR01770 361 LFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVM 428
 
Name Accession Description Interval E-value
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-327 0e+00

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 530.92  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    1 MNPYILATLLFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILGLTS 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPTNPTLLITLGLTS 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALT 240
Cdd:MTH00135 161 TLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALT 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  241 ALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPSTQ 320
Cdd:MTH00135 241 ALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPSTQ 320


                 ....*..
gi 22550266  321 LTYPLAT 327
Cdd:MTH00135 321 LTLPLAI 327
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-327 1.35e-127

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 368.48  E-value: 1.35e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    1 MNPYILATLLFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS-SSTLLIILGLT 159
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLlNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPAL 239
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  240 TALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLpST 319
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319


                 ....*...
gi 22550266  320 QLTYPLAT 327
Cdd:MTH00070 320 KTNNLLSL 327
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-324 3.26e-112

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 329.09  E-value: 3.26e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    1 MNPYILATLLFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS-SSTLLIILGLT 159
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSlNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPAL 239
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  240 TALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPST 319
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320


                 ....*
gi 22550266  320 QLTYP 324
Cdd:MTH00112 321 KNTLT 325
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-327 1.18e-109

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 322.57  E-value: 1.18e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    1 MNPYILATLLFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPS-SSTLLIILGLT 159
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSiNPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPAL 239
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  240 TALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPST 319
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320


                 ....*...
gi 22550266  320 QLTYPLAT 327
Cdd:MTH00105 321 KPMTLLPT 328
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-319 9.90e-99

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 294.95  E-value: 9.90e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    1 MNPYILATLLFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSS-STLLIILGLT 159
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALnSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPAL 239
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  240 TALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPST 319
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-315 2.98e-78

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 242.53  E-value: 2.98e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    1 MNPYILATLLFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 TGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQL-QPSSSTLLIILGLT 159
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISIsNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  160 STLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPAL 239
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 22550266  240 TALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWR 315
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWR 316
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 15-307 1.58e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 168.08  E-value: 1.58e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   15 LGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGqweiqqITHPLP 94
Cdd:MTH00160  16 MGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNLM------LFNNIS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   95 STMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILglTSTLIGGWGGLNQTQL 174
Cdd:MTH00160  90 SMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIIIIII--LSAIIGAIGGLNQTSL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  175 RKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALTALMPLILLSLGGLP 254
Cdd:MTH00160 168 RKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLP 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 22550266  255 PLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTLTISPNN 307
Cdd:MTH00160 248 PFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKN 300
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 10-318 4.60e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 150.81  E-value: 4.60e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   10 LFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIqqi 89
Cdd:MTH00144  10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFS--- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   90 thplpSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSS--TLLIILGLTSTLIGGWG 167
Cdd:MTH00144  87 -----MSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWlaYLLCVISVLSALVGSIG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  168 GLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLatSWAKAPALTALMPLIL 247
Cdd:MTH00144 162 GLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDL--GSLKPSYKTGLSIISL 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 22550266  248 LSLGG-LPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTLTISPNNLTGSTPWRLPS 318
Cdd:MTH00144 240 LLSLGgLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKVLNSS 311
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 15-327 1.11e-40

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 144.92  E-value: 1.11e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   15 LGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASvtnawlTGQWEIQQITHPLP 94
Cdd:MTH00011  17 LGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGM------TMMWSFPSLLKNIT 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   95 STMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLII-LGLTSTLIGGWGGLNQTQ 173
Cdd:MTH00011  91 ALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTsMAAMSALAGGLGGMNQTQ 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  174 LRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALTALMPLILLSLGGL 253
Cdd:MTH00011 171 LRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGL 250

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 22550266  254 PPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAMTlTISPNNLTGSTPWRLPSTQLTYPLAT 327
Cdd:MTH00011 251 PPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFM-YLSPTFSSLKSAPYEPKTKILISMCT 323
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-297 1.35e-38

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 139.04  E-value: 1.35e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    9 LLFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLlfasvtnawLTGQWEIQQ 88
Cdd:MTH00197   3 FLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALL---------LMGGSLSFS 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   89 --ITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFaLILQLQPSSSTLLIILGLTSTLIGGW 166
Cdd:MTH00197  74 nlYLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPL-LILAFNSSSFMGLLICSVLSSLIGGI 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  167 GGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLATSWAKAPALTALMPLI 246
Cdd:MTH00197 153 GGMNQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLS 232

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|.
gi 22550266  247 LLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSY 297
Cdd:MTH00197 233 FLSLGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-295 3.33e-21

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 92.79  E-value: 3.33e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   13 IGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHP-RAVEATTKYF-------------LTQATAAATLLFASVTNA 78
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLFILIAQNRGSgYSAEAGLKYFvlgalssglflfgCALLCGTTGGLHLSYINL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   79 WLTGQWEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLiILGL 158
Cdd:MTH00196  82 VLNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILL-IGGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  159 TSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQF----SPSITLLTLLTYFIMT---FSTFLAFKLNDSTNINTLAT 231
Cdd:MTH00196 161 FSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIgsfeSIQASLVYLFIYIIMSicvFSIILALNVYKNLIIEFSGL 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 22550266  232 SwAKAPALTALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRL 295
Cdd:MTH00196 241 S-RRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-266 8.26e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 90.45  E-value: 8.26e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    23 SSHWLLAWMGLEMNTLAIIPLMA-QHQHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITHPLPST----- 96
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTGGlnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    97 ------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLIL-STWQKLAPFALI---LQLQPSS---STLLIILGLTSTLI 163
Cdd:pfam00361  81 llllflLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGYGLIrrsLLYLPSSpfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   164 GGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFIMTFSTFLAFKL-----NDSTNINTLATSWA 234
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSviyrrVHTRNIRDYGGLAK 240

                         250       260       270
                  ....*....|....*....|....*....|..
gi 22550266   235 KAPALTALMPLILLSLGGLPPLTGSMPKWLIL 266
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLIL 272
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 13-266 1.35e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 85.84  E-value: 1.35e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   13 IGLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHQHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITH 91
Cdd:MTH00199 106 VALGSLLLVSSINWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETSIQGINS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   92 PLPS----TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILGLtSTLIGGWG 167
Cdd:MTH00199 186 ILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAVL-SIIYGAIG 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  168 GLNQTQLRKILAYSSIAHLGWMILVLQF----SPSITLLTLLTYFIMT---FSTFLAFKLNDSTNINTLATSwAKAPALT 240
Cdd:MTH00199 265 ALNQTKIKRLLAYSGIGHMGFILFGVAIgsfeSIQASLIYMIIYVIMSicsFSIILSLKLTKGLIVEVSGLS-RKNPVIA 343

                        250       260
                 ....*....|....*....|....*.
gi 22550266  241 ALMPLILLSLGGLPPLTGSMPKWLIL 266
Cdd:MTH00199 344 LTLALTFLSIAGIPPLAGFLSKWLIL 369
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 4-299 7.53e-16

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 77.85  E-value: 7.53e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   4 YILatLLFGIgLGTTITFASSHWLLAWMGLEMNTLAIIPLMA-QHQHPRAVEATTKYFLTqataaatllfASVTNAWL-- 80
Cdd:COG1007 105 YAL--LLFAT-LGMMLMASANDLLTLFLGLELLSLSLYVLVAfRRDDRRSSEAALKYFLL----------GALSSGFLly 171

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  81 --------TGQWEIQQITHPLPST------------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFA 140
Cdd:COG1007 172 gisllygaTGSLNLAGIAAALAAGganspllllglvLVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFA 251

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266 141 LILQL--------QPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYF 208
Cdd:COG1007 252 ALLRLlveafpglAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLaagtPLGVSAALFYLLAYL 331

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266 209 IMTFSTF-----LAFKLNDSTNINTLATSWAKAPALTALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAAL 283
Cdd:COG1007 332 FMNLGAFavillLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVL 411

                       330
                ....*....|....*.
gi 22550266 284 SALLSLYFYLRLSYAM 299
Cdd:COG1007 412 NSVISAYYYLRVVKAM 427
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
9-299 3.27e-14

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 72.93  E-value: 3.27e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    9 LLFGIgLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQH-QHPRAVEATTKYFLTqataaatllfASVTNAWL------- 80
Cdd:PRK05777 109 VLFAL-LGMMVMVSANDLLTLFLGLELLSLPLYALAALRrDRRRSLEAAIKYFVL----------GALASGFLlygmsll 177

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 ---TGQWEIQQITHPLPST------------MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALIL-- 143
Cdd:PRK05777 178 ygaTGSLSFAGIAKALADGsgnsllllfglvFLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLrl 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  144 ------QLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFIMTFS 213
Cdd:PRK05777 258 lvvafgGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLaagtAEGYSAVLFYLLAYLFMTLG 337

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  214 TF-----LAFKLNDSTNINTLATSWAKAPALTALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLS 288
Cdd:PRK05777 338 AFgvislLRRKGGEAESISDFAGLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIG 417

                        330
                 ....*....|.
gi 22550266  289 LYFYLRLSYAM 299
Cdd:PRK05777 418 AFYYLRVIKLM 428
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 23-299 1.47e-12

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 68.05  E-value: 1.47e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    23 SSHWLLAWMGLEMNTLAIIPLMA-QHQHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITHPLPSTMIT-- 99
Cdd:TIGR01770 121 SNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLLFLSNGMLNis 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   100 ----------LALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSS--------STLLIILGLTST 161
Cdd:TIGR01770 201 llllgivlilVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseawQIFLAIIAFLSM 280

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   162 LIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTY-FIMTFSTFLAF---------KLNDSTNINTLAT 231
Cdd:TIGR01770 281 LIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYiFIYALMSLGAFgvlsllrsyKDEWIEYISDFAG 360

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22550266   232 SWAKAPALTALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRLSYAM 299
Cdd:TIGR01770 361 LFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVVKVM 428
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 9-217 1.98e-11

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 64.88  E-value: 1.98e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    9 LLFGIGLGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAV---------EATTKYFLTQATAAATLLFASVTNAW 79
Cdd:MTH00198 193 LVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFG 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   80 LTGQ--------------WEIQQITHPLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQL 145
Cdd:MTH00198 273 FTGNegmlgtilsatletTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSL 352

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 22550266  146 QPSSStLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLA 217
Cdd:MTH00198 353 VITSK-LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQASWTYAVTYLVSALA 423
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 100-191 8.63e-09

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 56.49  E-value: 8.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   100 LALALKIGLAPLHAWLPEV-LQGLDLTTGLILSTWQKLAPFALI---LQLQPSSS----TLLIILGLTSTLIGGWGGLNQ 171
Cdd:TIGR01972 211 IAFAVKVPLFPLHTWLPDAhVEAPTAGSVILAGVLLKMGTYGFLrfnLPLFPDASlyfaPVLAALGVIAIIYGALIALAQ 290

                          90       100
                  ....*....|....*....|
gi 22550266   172 TQLRKILAYSSIAHLGWMIL 191
Cdd:TIGR01972 291 TDIKRLIAYSSISHMGFVLL 310
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-273 2.05e-08

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 55.15  E-value: 2.05e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  15 LGTTITFASSHWLLAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQITHPLP 94
Cdd:COG0651 118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLA 197

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  95 S----------TMITLALALKIGLAPLHAWLPE-----------VLQGLDLTTGL--ILSTWQKLAPFALILQLQPssst 151
Cdd:COG0651 198 EldpglllaafALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFLGT---- 273

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266 152 LLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFI--MTFST--FLA----FKLNDS 223
Cdd:COG0651 274 LLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLnhALAKAllFLAagaiERATGT 353

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|
gi 22550266 224 TNINTLATSWAKAPALTALMPLILLSLGGLPPLTGSMPKWLILKELTKQG 273
Cdd:COG0651 354 RDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAG 403
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 97-217 3.01e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 51.80  E-value: 3.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   97 MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI----------LQLQPSSSTLLIILGLTSTLIGG 165
Cdd:PRK08375 207 FVLLALALKAAVFPLHTWLPRAYPAAPPVVTALLSgLVTKVAVYALIriyftvfggdFRFALGLGWLLAVLALLSMLVGS 286

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 22550266  166 WGGLNQTQLRKILAYSSIAHLGWMILVLQFS----PSITLLTLLTYFIMTFSTFLA 217
Cdd:PRK08375 287 LAALGQDDVKRVLAYSTVSQMGYILLGLALLtplaLAAGLLHLLHHALMKGALFLA 342
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 78-193 7.03e-07

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 50.54  E-value: 7.03e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  78 AWLTGQWEIQQI----THPLPSTMITLALAL-------KIGLAPLHAWLPEVLQG-----------LDLTTGLILstwqk 135
Cdd:COG1009 186 GAIAGTLNFSELlaaaPTILSSPLLTLILLLlllgafgKSAQFPLHFWLPDAMEGptpvsallhaaTMVKAGVYL----- 260

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 22550266 136 LAPFALILQLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:COG1009 261 LARLSPLFALSPVWLTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQLGYMFLAL 318
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 290-327 9.07e-07

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 45.33  E-value: 9.07e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 22550266   290 YFYLRLSYAMTLTISPNNLTGSTPWRLPSTQLTYPLAT 327
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPT 38
ndhB CHL00049
NADH dehydrogenase subunit 2
 98-295 1.28e-06

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 49.62  E-value: 1.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQ----PSSST----LLIILGLTSTLIGGWGGL 169
Cdd:CHL00049 220 ITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASALATRIFdipfYFSSNewhlLLEILAILSMILGNLIAI 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  170 NQTQLRKILAYSSIAHLGW-MILVLQFSPSITLLTLLTYFIM-------TFSTFLAFKLNDST-NINTLATSWAKAPALT 240
Cdd:CHL00049 300 TQTSMKRMLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFyifmnlgTFACIVLFGLRTGTdNIRDYAGLYTKDPFLA 379

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 22550266  241 ALMPLILLSLGGLPPLTGSMPKWLILKELTKQGFAPTATLAALSALLSLYFYLRL 295
Cdd:CHL00049 380 LSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKI 434
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 100-191 1.88e-06

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 49.31  E-value: 1.88e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266 100 LALALKIGLAPLHAWLPEVLQ-----GLDLTTGLILstwqKLAPFALI---LQLQPSSS----TLLIILGLTSTLIGGWG 167
Cdd:COG1008 217 IAFAVKVPMFPFHTWLPDAHVeaptaGSVLLAGVLL----KMGGYGLLrfaLPLFPEASayfaPLLAALGVIGIIYGALV 292

                        90       100
                ....*....|....*....|....
gi 22550266 168 GLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:COG1008 293 ALAQTDLKRLIAYSSVSHMGFVLL 316
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 28-193 3.41e-06

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 48.39  E-value: 3.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   28 LAWMGLEMNTLAIIPLMAQHQHPRAVEATTKYF----------LTQATAAATLLFASVTNAWLTGQW-EIQQITHPLPST 96
Cdd:PRK06458 132 LMWVAIEATTLSSALLVGIYRTRASLEAAWKYIiicsvgvafaLFGTILVYANAATVMGDGEMAILWtELLKHASLLDPT 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   97 MITLALAL-------KIGLAPLHAWLPE-----------VLQGLDLTTGLILSTWQKLAPFALILQLQPSssTLLIILGL 158
Cdd:PRK06458 212 LMKLAFVFlligfgtKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYYILIDAAIGSDFPG--RLLLIFGL 289

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 22550266  159 TSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK06458 290 LSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFAL 324
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 81-193 1.56e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 46.46  E-value: 1.56e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 TGQWEIQQI-THPLPSTMITLALAL-------KIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTL 152
Cdd:PRK12644 184 AGTYRLSELlADPPTGPAVSVAVVLilvgalsKSAIVPFHFWLPGAMAAPTPVSAYLHAAAMVKAGIYLVARLAPGFADV 263

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 22550266  153 ------LIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK12644 264 pvwrptVLVLGLATMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
96-202 1.59e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 46.24  E-value: 1.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   96 TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI---LQLQPSSSTL----LIILGLTSTLIGGWG 167
Cdd:PRK07363 209 TGLLLGFGIKIPLVPLHTWLPDAYTEASPAVAILLGgVLAKLGTYGLLrfgLQLFPQTWSLvapgLAIIGTISVIYGALS 288

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 22550266  168 GLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLL 202
Cdd:PRK07363 289 AIAQKDIKRMVAYSSIGHMGYILVAAAAGTQLSLL 323
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 75-191 1.90e-05

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 45.96  E-value: 1.90e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   75 VTNAWLTGQWEIQQI-THPLPSTMITL-------ALALKIGLAPLHAWLPEVLQ-----GLDLTTGLILstwqKLAPFAL 141
Cdd:PRK05846 186 VVYYNATGTFDIADLlNLPLPPGVQYWlflaffiAFAVKMPMFPLHTWLPDAHVqaptaGSVLLAGILL----KMGAYGL 261

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 22550266  142 I---LQLQPSSS----TLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK05846 262 LrfsLPLFPDAShefaPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVTL 318
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 97-231 4.63e-05

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 44.09  E-value: 4.63e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   97 MITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSSTLLIILGLTSTLIGGWgglNQTQLRK 176
Cdd:MTH00091  62 FQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQMF---LLKSYKN 138

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 22550266  177 ILAYSSIAHLGWMILVLQFSPSITLLTLLTYFIMTFSTFLAFKLNDSTNINTLAT 231
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFVSWET 193
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 92-240 8.73e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 44.19  E-value: 8.73e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   92 PLPSTMITLALAL-----KIGLAPLHAWLPEV-----------LQGLDLTTG---------LILSTWQKLAPFALILqlq 146
Cdd:PRK12667 218 PPLALGVALALALwaftiKAAIFPNHFWLPDAhpaapspvsamLSGLVVNVGayaiirflyTIFGISPSLIDFRAAL--- 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  147 pssSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFI-------MTFSTFLAF- 218
Cdd:PRK12667 295 ---SPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIInhaiaksLLFLASGVFi 371

                        170       180
                 ....*....|....*....|..
gi 22550266  219 KLNDSTNINTLATSWAKAPALT 240
Cdd:PRK12667 372 HAAGTRDIDELAGLGRKMPIAS 393
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 111-207 1.36e-04

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 43.53  E-value: 1.36e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  111 LHAWLPEVLQGLDLTTGLI-LSTWQKLAPFALI-----LQLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00020 229 LHTWLPDAMEGPTPVSALIhAATMVTAGVFLLIrssplFEQAPLALIIVTIVGSLTVFFAATVGLVQNDLKKVIAYSTCS 308

                         90       100
                 ....*....|....*....|....
gi 22550266  185 HLGWMILVLQFSP-SITLLTLLTY 207
Cdd:MTH00020 309 QLGYMVVACGLSHySISLFHLMNH 332
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 100-191 2.56e-04

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 42.71  E-value: 2.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  100 LALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI---LQLQPSS----STLLIILGLTSTLIGGWGGLNQ 171
Cdd:PRK12561 193 IAFGVKLPIFPLHTWLPDAHGEASAPVSMILAgVLLKMGGYALIrfnVQMLPDAhvyfAPALAILGVVNIIYGALNAFAQ 272

                         90       100
                 ....*....|....*....|
gi 22550266  172 TQLRKILAYSSIAHLGWMIL 191
Cdd:PRK12561 273 DNVKRRLAYSSVSHMGFVLL 292
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
102-253 4.03e-04

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 41.96  E-value: 4.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  102 LALKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQ----PSSST----LLIILGLTSTLIGGWGGLNQTQ 173
Cdd:PRK02504 220 IAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLvtafPSFDEqwklLFTALAILSMVLGNVVALAQTS 299

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  174 LRKILAYSSIAHLGWMILVL----QFSPSITLLTLLTYFIMTFSTFLA---FKLNDSTN-INTLATSWAKAPALTALMPL 245
Cdd:PRK02504 300 MKRMLAYSSIGQAGFVMIGLvagtEAGYASMVFYLLAYLFMNLGAFACvilFSLRTGTDqISDYAGLYQKDPLLTLGLSL 379


                 ....*...
gi 22550266  246 ILLSLGGL 253
Cdd:PRK02504 380 CLLSLGGI 387
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 96-191 4.91e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 41.66  E-value: 4.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   96 TMITLALALKIGLAPLHAWLPE-----------VLQGLDLTTGLilstWQKLAPFALILQLQ--PSSSTLLIILGLTSTL 162
Cdd:PRK08676 210 LFIFIGFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGI----YGILRLSALLRQSGaaEQFSNVLIGLGIFSIA 285

                         90       100
                 ....*....|....*....|....*....
gi 22550266  163 IGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK08676 286 VAAFSMLSQRNLKKLIAFSSIEHMGLMLL 314
PRK12650 PRK12650
DUF4040 family protein;
110-190 5.16e-04

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 41.95  E-value: 5.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  110 PLHAWLPEVLQGLD-----------LTTGLILstwqkLAPFALILQLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKIL 178
Cdd:PRK12650 226 PFHFWLPEAMAAITpvsaflhaaavVKAGIYL-----LLRFSPVFHDVAVWNWLLIIVGMITALMGAVFAVQKTDLKKLT 300

                         90
                 ....*....|..
gi 22550266  179 AYSSIAHLGWMI 190
Cdd:PRK12650 301 AYSTVSQLGWIV 312
PRK07376 PRK07376
NADH-quinone oxidoreductase subunit L;
110-191 5.67e-04

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236005 [Multi-domain]  Cd Length: 673  Bit Score: 41.55  E-value: 5.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  110 PLHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQPSSS------TLLIILGLTSTLIGGWGGLNQTQLRKILAYSSI 183
Cdd:PRK07376 245 PLHVWLPDAMEGPTPISALIHAATMVAAGVFLVARMYPVFEqfpavmTVIAWTGAITAFLGASIALTQNDIKKGLAYSTI 324


                 ....*...
gi 22550266  184 AHLGWMIL 191
Cdd:PRK07376 325 SQLGYMVM 332
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 111-193 7.03e-04

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 41.48  E-value: 7.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  111 LHAWLPEVLQGLDLTTGLILSTWQKLAPFALILQLQP----SSSTLLII--LGLTSTLIGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00032 244 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPlfekAPLTLLIItiFGALTAFFAATVGLVQNDLKKVIAYSTCS 323


                 ....*....
gi 22550266  185 HLGWMILVL 193
Cdd:MTH00032 324 QLGYMVLII 332
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
98-191 8.24e-04

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 40.84  E-value: 8.24e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   98 ITLALALKIGLAPLHAWLPE-----------VLQG--LDLTT--------GLILSTWQKLAPFalilqlqpssstlLIIL 156
Cdd:PRK06473 211 ILVGFGIKIPLVPFHTWLPDahveastpvsvLLAGvlLKLGTygllrfgvGLFPEAWVYLAPW-------------LATW 277

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 22550266  157 GLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK06473 278 AVVSVLYGASCAIAQKDMKKMVAYSSIGHMGYILL 312
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 98-193 1.11e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 40.68  E-value: 1.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   98 ITLALALKIGLAPLHAWLPEV-----LQGLDLTTGLILstwqKLAPFALILQLQP-------SSSTLLIILGLTSTLIGG 165
Cdd:MTH00226 236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILL----KLGGYGLVRLSWPilplgaqNLAPAVIAMGIVGIVYGS 311

                         90       100
                 ....*....|....*....|....*...
gi 22550266  166 WGGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:MTH00226 312 FATCRQIDVKRLVAYSSVAHMGLVSITL 339
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-200 1.19e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 40.42  E-value: 1.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  100 LALALKIGLAPLHAWLPEV-----LQGLDLTTGLILstwqKLAPFALI---LQLQPSSS----TLLIILGLTSTLIGGWG 167
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KLGGYGFIrfsWPLLPEASeyfsPLIQTLSLLAIIYGSLT 289

                         90       100       110
                 ....*....|....*....|....*....|...
gi 22550266  168 GLNQTQLRKILAYSSIAHLGWMILVLqFSPSIT 200
Cdd:MTH00217 290 TCRQVDLKRIIAYSSVAHMGLVTLGI-FSHTIQ 321
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 1-205 2.24e-03

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 39.71  E-value: 2.24e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266    1 MNPYILATLLFgIGLGTTITFasshwLLAWMglEMNTLAIIPLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWL 80
Cdd:PRK08667 117 TALFILSMLGV-VASANTFSF-----LFFWE--IMALSSFFLVMNDYQEEETQRAGIFYFVMTQLSTVFLMLGIIVLFIQ 188

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   81 TGQWEIQQITHP-----LPSTMITLALALKIGLAPLHAWLPEVLQGLD-----LTTGLILstwqKLAPFALILQLQPSSS 150
Cdd:PRK08667 189 TGSFELSPLGASagilsLVFLLLFLGFGIKAGIIPFHKWLPYAHPASPsnvsaLMSGVML----KVAVYGLVRFLMDVLS 264

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22550266  151 ------TLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIAHLG--------WMILVLQFSPSITLLTLL 205
Cdd:PRK08667 265 pelwwgVLILLAGSISALLGVIYALKEHDLKGLLAYSSIENIGiilmgiglYVIFGVYGLDTLALLALG 333
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 96-193 2.46e-03

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 39.36  E-value: 2.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   96 TMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILSTW-QKLAPFAL-----ILQLQPSSST---LLIILGLTSTLIGGW 166
Cdd:PRK08377 210 ALLIFGLAVEAELFPLNAWAPDAYQAAPHPITVMFSAFvVKAGLYAMarilyLMQNANGWSSvlkLVIIMATLTVFFAEL 289

                         90       100
                 ....*....|....*....|....*..
gi 22550266  167 GGLNQTQLRKILAYSSIAHLGWMILVL 193
Cdd:PRK08377 290 SALRQKNVKRMIAYSSIGQVGMIALAL 316
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 98-274 3.05e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 39.33  E-value: 3.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   98 ITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI-----------LQLQPSSSTLLIILGLTSTLIGG 165
Cdd:PRK12662 215 IMVGLFIKAALFPFHKWLIQAYSEAPSFISVFFSgTSTKVMIYLIIrivydvfkanfVFTTLPFNNVFMILAALAIVFGS 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  166 WGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSITLLTLLTYFI---------MTFSTFLAFKLnDSTNINTLATSWAKA 236
Cdd:PRK12662 295 VLAILSKDIKRIFAYSSISHIGYIILAVSLNTYYGLAAAVAYIVnhsivksalFMVSGSISYHF-GTTKLEDCLNLWKSM 373

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 22550266  237 PALTALMPLILLSLGGLPPLTGSMPKWLILKELTKQGF 274
Cdd:PRK12662 374 PKITLAFVLLSLSLIGMPPTSGFVAKWYILDAFIKSNA 411
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 97-190 3.11e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 39.18  E-value: 3.11e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   97 MITLALALKIGLAPLHAWLPE-----------VLQGLdLTtglilstwqKLAPFALI-----LQLQPSSSTLLIILGLTS 160
Cdd:PRK12665 214 VLLVAFGIKAAVFPLSFWLPDsyptapapvtaVFAGL-LT---------KVGVYAIIrthtlLFPGGGLDTLLMVVALLT 283

                         90       100       110
                 ....*....|....*....|....*....|
gi 22550266  161 TLIGGWGGLNQTQLRKILAYSSIAHLGWMI 190
Cdd:PRK12665 284 MVVGILGAIAQSDIKRLLSFTLVSHIGYMV 313
NDH_I_L TIGR01974
proton-translocating NADH-quinone oxidoreductase, chain L; This model describes the 12th ...
 110-193 5.59e-03

proton-translocating NADH-quinone oxidoreductase, chain L; This model describes the 12th (based on E. coli) structural gene, L, of bacterial NADH dehydrogenase I, as well as chain 5 of the corresponding mitochondrial complex I and subunit 5 (or F) of the chloroplast NAD(P)H-plastoquinone dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273905 [Multi-domain]  Cd Length: 609  Bit Score: 38.42  E-value: 5.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   110 PLHAWLPEVLQGLDLTTGLILSTWQKLAPFALI------LQLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSI 183
Cdd:TIGR01974 231 PLHTWLPDAMEGPTPVSALIHAATMVTAGVYLVartsplFELSPTALYLVTIIGAITALFAATVALVQNDIKRILAYSTM 310

                          90
                  ....*....|
gi 22550266   184 AHLGWMILVL 193
Cdd:TIGR01974 311 SQLGYMFLAL 320
ND5 MTH00210
NADH dehydrogenase subunit 5; Provisional
 111-192 5.67e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 177253 [Multi-domain]  Cd Length: 616  Bit Score: 38.45  E-value: 5.67e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  111 LHAWLPEVLQGLDLTTGLILSTWQKLAPFALIL------QLQPSSSTLLIILGLTSTLIGGWGGLNQTQLRKILAYSSIA 184
Cdd:MTH00210 230 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLIIrsgplfEGSPLALTIVTILGALTAFFAATVGVVQNDLKKVIAYSTCS 309


                 ....*...
gi 22550266  185 HLGWMILV 192
Cdd:MTH00210 310 QLGYMVMV 317
PRK08168 PRK08168
NADH-quinone oxidoreductase subunit L;
18-191 5.78e-03

NADH-quinone oxidoreductase subunit L;


Pssm-ID: 236171 [Multi-domain]  Cd Length: 516  Bit Score: 38.14  E-value: 5.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   18 TITFASSHWLL---AWM--GLEMNTLaiipLMAQHQHPRAVEATTKYFLTQATAAATLLFASVTNAWLTGQWEIQQI--- 89
Cdd:PRK08168 114 HLLVLSDHLLVliaAWAaiSLALHRL----LCFYPDRPFARLAAHKKFIADRLAELLLLAAAALAYLEVGSLSLSALwah 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   90 ------THPLPSTMITLALA--LKIGLAPLHAWLPEVLQGLDLTTGLILSTWQKLAPFALI-----LQLQPSSSTLLIIL 156
Cdd:PRK08168 190 laaqgaSPSLQAAALLLVLAviLKTAQLPVHGWLIQVMEAPTPVSALLHAGVVNLGGFVLIrfaplLEQAPPARWLLVLV 269

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 22550266  157 GLTSTLIGGWGGLNQTQLRKILAYSSIAHLGWMIL 191
Cdd:PRK08168 270 GLATAVLAGLVMLTRISIKVRLAWSTVAQMGFMLL 304
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 100-203 6.27e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 38.12  E-value: 6.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266  100 LALALKIGLAPLHAWLPEV-----LQGLDLTTGLILstwqKLAPFALI---LQLQPSSST----LLIILGLTSTLIGGWG 167
Cdd:MTH00204 217 LSLAVKIPQIPFHIWLPQAhveapVAGSVILAGILL----KLGGYGFLrfsWPLFPAASEyfapLIVMLSVIAVIYGSLT 292

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 22550266  168 GLNQTQLRKILAYSSIAHLGWMILVLqFSPSITLLT 203
Cdd:MTH00204 293 TCRQVDFKRLIAYSSVAHMGLVPLGL-FTHTIEGLV 327
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 92-216 7.44e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 38.01  E-value: 7.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22550266   92 PLPSTMITLALALKIGLAPLHAWLPEVLQGLDLTTGLILS-TWQKLAPFALI--LQLQPSSSTLLIILGLTSTLIGGWGG 168
Cdd:PRK07234 184 PEAFALIALGLLVKGGIFVSGLWLPLTHSEAEPPVSALLSgVVVKAGVFPLVrcALDVPGLDLIVRIFGVGTALLGVLFA 263

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 22550266  169 LNQTQLRKILAYSSIAHLGWMILvlqfSPSITLLTLLTYFIMTFSTFL 216
Cdd:PRK07234 264 LLEKDLKRMLAFSTISQLGFILA----APLVGGLYALAHGLVKSTLFL 307
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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