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Conserved domains on  [gi|224976612|gb|ACN71298|]
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tgrC1 [Dictyostelium discoideum]

Protein Classification

IPT/TIG domain-containing protein( domain architecture ID 10089206)

IPT/TIG domain-containing protein similar to Dictyostelium discoideum tiger protein C1/D1

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
IPT_PCSR cd00603
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup ...
308-380 2.90e-05

IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the macrophage-stimulating receptors and of fibrocystin. Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT_PCSR domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.


:

Pssm-ID: 238337 [Multi-domain]  Cd Length: 90  Bit Score: 43.60  E-value: 2.90e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 224976612 308 IVTIKGEKLSSTLnplLTPSITIGDKLCTFIKSTPTELECKL-EKNELGGKNLTVNVNFGGCDSTSPNDVSFTY 380
Cdd:cd00603   18 RLTITGSNLGSGS---PRVRVTVGGVPCKVLNVSSTEIVCRTpAAATPGEGPVEVTVDGANVSARVLSNTTFTY 88
 
Name Accession Description Interval E-value
IPT_PCSR cd00603
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup ...
308-380 2.90e-05

IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the macrophage-stimulating receptors and of fibrocystin. Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT_PCSR domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.


Pssm-ID: 238337 [Multi-domain]  Cd Length: 90  Bit Score: 43.60  E-value: 2.90e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 224976612 308 IVTIKGEKLSSTLnplLTPSITIGDKLCTFIKSTPTELECKL-EKNELGGKNLTVNVNFGGCDSTSPNDVSFTY 380
Cdd:cd00603   18 RLTITGSNLGSGS---PRVRVTVGGVPCKVLNVSSTEIVCRTpAAATPGEGPVEVTVDGANVSARVLSNTTFTY 88
TIG pfam01833
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These ...
308-380 2.18e-03

IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. CAUTION: This family does not currently recognize a significant number of members.


Pssm-ID: 460355 [Multi-domain]  Cd Length: 84  Bit Score: 37.81  E-value: 2.18e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 224976612  308 IVTIKGEKLSSTLNpllTPSITIGDKLCTFIKSTPTELECKLEKNELGGKNLTVNVNFGGcdsTSPNDVSFTY 380
Cdd:pfam01833  18 TITITGSNFGTDSS---DLKVTIGGTPCTVISVSSTTIVCTTPPGTSGLVNVSVTVGGGG---ISSSPLTFTY 84
 
Name Accession Description Interval E-value
IPT_PCSR cd00603
IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup ...
308-380 2.90e-05

IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the macrophage-stimulating receptors and of fibrocystin. Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT_PCSR domain present preceeded by SEMA (semaphorin) and PSI (plexin, semaphorin, integrin) domains.


Pssm-ID: 238337 [Multi-domain]  Cd Length: 90  Bit Score: 43.60  E-value: 2.90e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 224976612 308 IVTIKGEKLSSTLnplLTPSITIGDKLCTFIKSTPTELECKL-EKNELGGKNLTVNVNFGGCDSTSPNDVSFTY 380
Cdd:cd00603   18 RLTITGSNLGSGS---PRVRVTVGGVPCKVLNVSSTEIVCRTpAAATPGEGPVEVTVDGANVSARVLSNTTFTY 88
TIG pfam01833
IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These ...
308-380 2.18e-03

IPT/TIG domain; This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA binding. CAUTION: This family does not currently recognize a significant number of members.


Pssm-ID: 460355 [Multi-domain]  Cd Length: 84  Bit Score: 37.81  E-value: 2.18e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 224976612  308 IVTIKGEKLSSTLNpllTPSITIGDKLCTFIKSTPTELECKLEKNELGGKNLTVNVNFGGcdsTSPNDVSFTY 380
Cdd:pfam01833  18 TITITGSNFGTDSS---DLKVTIGGTPCTVISVSSTTIVCTTPPGTSGLVNVSVTVGGGG---ISSSPLTFTY 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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