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Conserved domains on  [gi|22135004|gb|AAM93047|]
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NADH dehydrogenase subunit 4, partial (mitochondrion) [Chelonoidis vicina]

Protein Classification

proton-conducting transporter membrane subunit( domain architecture ID 1562513)

proton-conducting transporter membrane subunit such as NADH dehydrogenase subunit 2, 4, or N, which shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain

EC:  7.1.-.-
Gene Ontology:  GO:0005886

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Proton_antipo_M super family cl39059
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-243 6.83e-152

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


The actual alignment was detected with superfamily member MTH00124:

Pssm-ID: 476862 [Multi-domain]  Cd Length: 457  Bit Score: 430.77  E-value: 6.83e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00124 215 WLPKAHVEAPIAGSMVLAAILLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHM 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00124 295 GLVIAATMIQTPWSLSGAMILMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTIN 374

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00124 375 LMGELTIMTSLFNWSPTTIILTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELI 454


                 ...
gi 22135004  241 WGT 243
Cdd:MTH00124 455 SGT 457
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-243 6.83e-152

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 430.77  E-value: 6.83e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00124 215 WLPKAHVEAPIAGSMVLAAILLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHM 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00124 295 GLVIAATMIQTPWSLSGAMILMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTIN 374

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00124 375 LMGELTIMTSLFNWSPTTIILTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELI 454


                 ...
gi 22135004  241 WGT 243
Cdd:MTH00124 455 SGT 457
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-233 1.02e-58

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 192.99  E-value: 1.02e-58
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPL-SKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:COG1008 231 WLPDAHVEAPTAGSVLLAGVLLKMGGYGLLRFALPLFPEaSAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSH 310

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:COG1008 311 MGFVLLGIFALNPLGLQGAVLQMVSHGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTS 390

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 22135004 160 NLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALL 233
Cdd:COG1008 391 GFVGEFLVLLGAFQVNPWLAILAALGLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLL 464
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-186 1.46e-50

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 166.72  E-value: 1.46e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004     1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:pfam00361 104 WLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHM 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLA-NTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:pfam00361 184 GYMLIALGAGTIYGIQAAIFHLLTHGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTA 263

                         170       180
                  ....*....|....*....|....*..
gi 22135004   160 NLMGELTIIISLFNWSNITILMTGLGT 186
Cdd:pfam00361 264 GFLGKFLILAAAVAASWIFLVLAGVVG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-219 8.15e-50

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 169.74  E-value: 8.15e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004     1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDP-LSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:TIGR01972 225 WLPDAHVEAPTAGSVILAGVLLKMGTYGFLRFNLPLFPdASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISH 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:TIGR01972 305 MGFVLLGIFSFNELGISGAVFQMISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTS 384

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 22135004   160 NLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGE-TPSHLKSIPPTHTRE 219
Cdd:TIGR01972 385 GFVGEFLILLGSFKVNPVVAFLAALGIVLAAAYMLTLYKRVFFGElSNPEVAEFPDLNGRE 445
 
Name Accession Description Interval E-value
ND4 MTH00124
NADH dehydrogenase subunit 4; Provisional
 1-243 6.83e-152

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214427 [Multi-domain]  Cd Length: 457  Bit Score: 430.77  E-value: 6.83e-152
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00124 215 WLPKAHVEAPIAGSMVLAAILLKLGGYGIIRITLLLPPLSNTLHYPFLTLALWGALMTSLICLRQTDLKSLIAYSSVSHM 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00124 295 GLVIAATMIQTPWSLSGAMILMIAHGLTSSMLFCLANTNYERTHSRTLLLTRGLQLLLPLMTTWWLLANLTNMALPPTIN 374

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00124 375 LMGELTIMTSLFNWSPTTIILTGLATLITASYTLYMFLSTQRGTLPTHITTIQPTHTREHLLMTLHIIPLLLLILKPELI 454


                 ...
gi 22135004  241 WGT 243
Cdd:MTH00124 455 SGT 457
ND4 MTH00068
NADH dehydrogenase subunit 4; Provisional
 1-244 5.08e-140

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214417 [Multi-domain]  Cd Length: 458  Bit Score: 400.45  E-value: 5.08e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00068 215 WLPKAHVEAPIAGSMILAAVLLKLGGYGILRISILLTPLSKELSYPFIILALWGVLMTSLICLRQTDLKSLIAYSSVSHM 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00068 295 GLVIAAALIQTPWSFSGAIILMISHGLTSSALFCLANTNYERTHSRTLLLLRGAQTILPLMATWWLLSNLSNMALPPSPN 374

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00068 375 LWGELTIMVSLFNWSNWTILITGLGTLITAAYTLYMFLMTQRGPLPNHLKTLFPTYTREHLLLALHILPMLLLILKPELI 454


                 ....
gi 22135004  241 WGTF 244
Cdd:MTH00068 455 SGMF 458
ND4 MTH00110
NADH dehydrogenase subunit 4; Provisional
 1-245 1.71e-132

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177172 [Multi-domain]  Cd Length: 459  Bit Score: 381.55  E-value: 1.71e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00110 215 WLPKAHVEAPIAGSMVLAAILLKLGGYGMMRITIILNPLTEFMAYPFLMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHM 294

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00110 295 ALVIVAILIQTPWSFMGATALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMATWWLLASLTNLALPPTIN 374

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00110 375 LIGELFVIMSSFSWSNITIILMGLNMLITALYSLYMLITTQRGKLTHHINNIKPSFTRENTLMALHLLPLLLLSLNPKII 454


                 ....*
gi 22135004  241 WGTFY 245
Cdd:MTH00110 455 LGPTY 459
ND4 MTH00127
NADH dehydrogenase subunit 4; Provisional
 1-242 9.67e-112

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177186 [Multi-domain]  Cd Length: 459  Bit Score: 328.84  E-value: 9.67e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00127 216 WLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRMMVMLDPLTKELSYPFIILALWGIIMTGSICLRQTDLKSLIAYSSVSHM 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00127 296 GLVAGGILIQTPWGFTGALILMIAHGLTSSALFCLANTNYERTHSRTMLLARGLQMILPLMATWWFIASLANLALPPLPN 375

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00127 376 LMGELMIITSLFNWSPWTLALTGLGTLITAGYSLYMFLMTQRGPLPDHIIALNPSHTREHLLMALHLLPLLLLILKPELI 455


                 ..
gi 22135004  241 WG 242
Cdd:MTH00127 456 WG 457
ND4 MTH00206
NADH dehydrogenase subunit 4; Provisional
 1-240 4.48e-108

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214458 [Multi-domain]  Cd Length: 450  Bit Score: 318.81  E-value: 4.48e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00206 211 WLPKAHVEAPVAGSMVLAGVLLKLGGYGMMRIILILGPSTKLSSYFFIILGLWGSIMTSSICLRQTDLKSLIAYSSVSHM 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00206 291 SLVTAGILSGSPWGFKGALLLMIAHGLVSSALFCLANLLYERSHTRTILGNRGLQMILPLLSFWWLLFFLANLGLPPFPN 370

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00206 371 LFGELLIITSLFSWSNFTLPLLGLGFLFTAIYSLYMFVMTQHGKTPNHLLSLSPSSTREHLLLFLHLFPVILLILNPNLI 450
ND4 MTH00044
NADH dehydrogenase subunit 4; Validated
 1-240 3.39e-90

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214411 [Multi-domain]  Cd Length: 458  Bit Score: 273.39  E-value: 3.39e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLD-PLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:MTH00044 216 WLPKAHVEAPVAGSMILAAILLKLGGYGLIRLINLFSlPSANNISFILIVFCCWGALITSIICLRQTDLKALIAYSSVGH 295

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:MTH00044 296 MSLVAAGIFSGTNWGINGALILMIAHGLVSSALFCLANILYERSGTRTLSITRGFKLITPLLPLWWLIFCAANLGLPPLP 375

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  160 NLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPEL 239
Cdd:MTH00044 376 NLIGELLIISSIISWSILSFPIIGLATVFGAIYSLLIYQLTNSGSFPSWISNVSPISSREHLLIFLHLLPLILIIINPNI 455


                 .
gi 22135004  240 I 240
Cdd:MTH00044 456 I 456
ND4 MTH00163
NADH dehydrogenase subunit 4; Provisional
 1-240 1.21e-89

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214443 [Multi-domain]  Cd Length: 445  Bit Score: 271.64  E-value: 1.21e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00163 203 WLPKAHVEAPVSGSMILAGVLLKLGGYGLLRVMSFFSKLGLKFNYIWISISLVGGVIVSLICLRQVDLKSLIAYSSVAHM 282

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00163 283 GLVLGGLMTFSYWGLMGSLLMMIGHGLCSSGLFCLANIIYERLGSRSLLINKGLLNFMPSMSLWWFLLSSSNMAAPPSLN 362

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00163 363 LLGEISLINSLISWSKLSMIFLMLLSFFSAAYSLYLYSYSQHGKYYSGLYSCSSGKVREYLLLFLHWLPLNLLILKSDLF 442
ND4 MTH00150
NADH dehydrogenase subunit 4; Provisional
 1-240 4.20e-82

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214435 [Multi-domain]  Cd Length: 417  Bit Score: 251.68  E-value: 4.20e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00150 174 WLPKAHVEAPVAGSMILAGILLKLGGYGILRMMMVFSLSSSSFSIFLISLSLWGGVLTSLICLRQSDVKSLIAYSSVGHM 253

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00150 254 SLVLAGVLSNTSWGWVGALIMMVSHGFCSSGLFCLANYTYEKVHSRSLFLSKGMLMLYPSLSLWWFLFCIINMAAPPSLN 333

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00150 334 LLSEIMIFPSLISYSPWFFVPLGLMVFLSGLYSLYLYTSIQHGGSSSFLKPFNELKSSEMLLLLLHWVPLLLLILKSDLL 413
ND4 MTH00205
NADH dehydrogenase subunit 4; Provisional
 1-240 2.75e-74

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214457 [Multi-domain]  Cd Length: 448  Bit Score: 232.56  E-value: 2.75e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00205 207 WLPKAHVEAPVSGSMILAGVLLKLGGYGLIRITSMLYKLNSNFSELFFSISLWGGVMTGMICLRQVDLKSLIAYSSVGHM 286

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00205 287 GLMVVGVFSNTSWGMNGAIIMMVAHGLCSSGMFALANVNYERTNSRSMLMNKGVLNTFPFLVLMWFLLISCNMAAPPSLN 366

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00205 367 LASEILLIMSLLSSSKISGIPLSLISFLSGAYSLYLYSQSQHGKVSSQISSFLAISEREYYILILHWFPLNILILKLKIF 446
ND4 MTH00014
NADH dehydrogenase subunit 4; Validated
 1-240 1.79e-73

NADH dehydrogenase subunit 4; Validated


Pssm-ID: 214399 [Multi-domain]  Cd Length: 452  Bit Score: 230.40  E-value: 1.79e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00014 209 WLPKAHVEAPVAGSMILAGILLKLGGYGLLRMSSLFMHINKSLSAPFSSISLVGAVITSLICIRQPDLKSLIAYSSVGHM 288

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00014 289 GLMTAGIMSNTSWGWQGALAMMIAHGLCSSALFALANMTYETTHTRSLFLTKGLLSLFPTMTMWWFLLSAANMAAPPSIN 368

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPELI 240
Cdd:MTH00014 369 LLSEIMLLTSILSSSLSTAILLAITSFLAAAYSLFLYTSTQHGSPPSFMNPLNLFTPRNHTLMTLHLVPLFILILKPDLI 448
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 1-233 1.02e-58

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 192.99  E-value: 1.02e-58
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPL-SKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:COG1008 231 WLPDAHVEAPTAGSVLLAGVLLKMGGYGLLRFALPLFPEaSAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSH 310

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:COG1008 311 MGFVLLGIFALNPLGLQGAVLQMVSHGLITAALFLLVGVLYDRTHTRDIADLGGLAKRMPVLAALFLLAALASLGLPGTS 390

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 22135004 160 NLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALL 233
Cdd:COG1008 391 GFVGEFLVLLGAFQVNPWLAILAALGLILTAAYLLWMYQRVFFGPLKEELAELPDLNPRELAVLAPLAALILLL 464
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-186 1.46e-50

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 166.72  E-value: 1.46e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004     1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:pfam00361 104 WLPDAYEGAPTPVSALLAATLVKAGGYGLIRRSLLYLPSSPFIQQILLILAIISMLLGSLAALVQTDIKRLLAYSSISHM 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLA-NTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:pfam00361 184 GYMLIALGAGTIYGIQAAIFHLLTHGLFSAGLFLCAgSVIYRRVHTRNIRDYGGLAKTMPILALVFLVAMLSLAGLPPTA 263

                         170       180
                  ....*....|....*....|....*..
gi 22135004   160 NLMGELTIIISLFNWSNITILMTGLGT 186
Cdd:pfam00361 264 GFLGKFLILAAAVAASWIFLVLAGVVG 290
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 1-219 8.15e-50

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 169.74  E-value: 8.15e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004     1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDP-LSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:TIGR01972 225 WLPDAHVEAPTAGSVILAGVLLKMGTYGFLRFNLPLFPdASLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISH 304

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:TIGR01972 305 MGFVLLGIFSFNELGISGAVFQMISHGLITAALFLLVGVLYERAHTRDIAKYGGLANKMPVLAAFFMLFAMASLGLPGTS 384

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 22135004   160 NLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGE-TPSHLKSIPPTHTRE 219
Cdd:TIGR01972 385 GFVGEFLILLGSFKVNPVVAFLAALGIVLAAAYMLTLYKRVFFGElSNPEVAEFPDLNGRE 445
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 1-234 7.49e-49

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 167.30  E-value: 7.49e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPL-SKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:PRK05846 233 WLPDAHVQAPTAGSVLLAGILLKMGAYGLLRFSLPLFPDaSHEFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISH 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLL----LTRNMqlalPLMGLWWLLASLTNMAL 155
Cdd:PRK05846 313 MGFVTLGIFAGNQLGIQGAIFQMISHGLSSAALFLLVGVLYDRLHTRDIAdyggLAKVM----PVLAAFFLFFAMASLGL 388

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22135004  156 PPTINLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLmtlhILPMALLT 234
Cdd:PRK05846 389 PGTSGFVGEFLILLGSFQVNPVIAFIATTGLILAAVYSLWLYQRVMFGPVKNEVAKLKDLNGRELLI----LLPLVALL 463
ND4 MTH00204
NADH dehydrogenase subunit 4; Provisional
 1-240 3.34e-48

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 164750 [Multi-domain]  Cd Length: 485  Bit Score: 165.62  E-value: 3.34e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVM-ALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:MTH00204 231 WLPQAHVEAPVAGSVILAGILLKLGGYGFLRFSWPLFPAASEYFAPLIVMlSVIAVIYGSLTTCRQVDFKRLIAYSSVAH 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:MTH00204 311 MGLVPLGLFTHTIEGLVAAVFLMLAHGFVSSALFIAVTFLYERHHTRLIKYYRGLTLTMPLFVIIMLVLSLANMGFPLSC 390

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  160 NLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALLTTKPEL 239
Cdd:MTH00204 391 NFVGEFFSLLAAFEYSLGLGVLVTSGMVWSAAYSLYLYNRISFGGGSNYLLFSRDLNRRELLAILPLIIAIFLLGIVPFI 470


                 .
gi 22135004  240 I 240
Cdd:MTH00204 471 I 471
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 1-196 2.39e-46

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 160.60  E-value: 2.39e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPF-MVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:MTH00217 228 WLPQAHVEAPVAGSVILAGVLLKLGGYGFIRFSWPLLPEASEYFSPLiQTLSLLAIIYGSLTTCRQVDLKRIIAYSSVAH 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:MTH00217 308 MGLVTLGIFSHTIQGLVAAIFLMLAHGLVSSALFIAVTFLYERHHTRLIKYYRGMVITMPLFGILMLLLVLANASIPLSC 387

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 22135004  160 NLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYM 196
Cdd:MTH00217 388 NFVGEFLSLLAAFEYSYIVGVLASLGMVLSAGYSIYL 424
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 1-233 3.45e-45

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 157.78  E-value: 3.45e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPL-SKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:MTH00226 252 WLPKAHVEAPVAGSVLLAGILLKLGGYGLVRLSWPILPLgAQNLAPAVIAMGIVGIVYGSFATCRQIDVKRLVAYSSVAH 331

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:MTH00226 332 MGLVSITLVTHDIIGLTGSIFIMLAHGIVSSLLFILVTILYDRHHTRLIKYYRGLSITMPIWGTIMIVTSLANVAVPPSG 411

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 22135004  160 NLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGeTPSHLKSIPPTHTREHLLMTLHILPMALL 233
Cdd:MTH00226 412 NFIGEYLSILSSFNWNPIIGVFVCSGVILSAVYSFYFANRVTFG-APGNLITFARDVNRREFYITASMVFFAFL 484
ND4 MTH00094
NADH dehydrogenase subunit 4; Provisional
 1-198 1.49e-35

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 177157 [Multi-domain]  Cd Length: 403  Bit Score: 130.41  E-value: 1.49e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRItmtLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00094 173 WLPKAHVEAPTTASMLLAGLLLKLGTAGFLRI---LGSLNFVYNNFWIIFSLLGMILSSFCCVFQSDSKSLAAYSSVTHM 249

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:MTH00094 250 SFLLLSLVYMSMSGKLSGLMMMLAHGYTSTLMFYLIGEFYHISKSRLIYFMNSFFSSSMFFGLIFSLVFLSNSGVPPSLS 329

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLT 198
Cdd:MTH00094 330 FFSEFLIISNSFMKNKFSFFFIFFYFLVSFYYSLFLIV 367
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
1-221 6.08e-31

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 119.03  E-value: 6.08e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFM-VMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:PRK06473 227 WLPDAHVEASTPVSVLLAGVLLKLGTYGLLRFGVGLFPEAWVYLAPWLaTWAVVSVLYGASCAIAQKDMKKMVAYSSIGH 306

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTR---NMQLALPLMGLWWLLASLTNMALP 156
Cdd:PRK06473 307 MGYILLAAAAATPLSILAAVFQMISHGLISALLFLLVGVVYKKTGSRDVDVLRgllNPERGLPITGSLMILGVMASAGIP 386

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 22135004  157 PTINLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHL 221
Cdd:PRK06473 387 GMVGFIAEFLVFRGSFPIFPVQTLLCMIGTGLTAVYFLLLVNRVFFGRLTAELSNLPRVLWSERL 451
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-197 9.83e-31

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 118.60  E-value: 9.83e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPfmVMALWGV--IMTSSIC-LRQTDLKSLIAYSSV 77
Cdd:PRK12561 207 WLPDAHGEASAPVSMILAGVLLKMGGYALIRFNVQMLPDAHVYFAP--ALAILGVvnIIYGALNaFAQDNVKRRLAYSSV 284

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   78 SHMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPP 157
Cdd:PRK12561 285 SHMGFVLLGIAAFTDLGISGAMLQMISHGLIAAALFFLTGVTYERTHTLSIPNMGGLAKVMPKTFALFTASSMASLALPG 364

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 22135004  158 TINLMGELTIIISLFN-------WSNITILMTGLGTLITAIYTLYML 197
Cdd:PRK12561 365 MSGFVSELTVFLGITSsdvysstFRTITILLAAVGLILTPIYLLSML 411
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 1-201 1.20e-28

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 112.16  E-value: 1.20e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDP--LSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVS 78
Cdd:COG0651 227 WLPDAYPAAPSPVSALLSGLLTKVGVYAILRVLTLLFGadPALFLGTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVS 306

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  79 HMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPT 158
Cdd:COG0651 307 QIGYILLGLGLGTPLGLAGALFHLLNHALAKALLFLAAGAIERATGTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPL 386

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 22135004 159 INLMGELTIIISLFNWSNITILMTGL-GTLITAIYTLYMLTTTQ 201
Cdd:COG0651 387 SGFVSKWLLLQAALEAGAWLLAAVLLlSSLLTLAYFVRIFGRAQ 430
ndhD CHL00011
NADH dehydrogenase subunit 4
 1-197 8.25e-28

NADH dehydrogenase subunit 4


Pssm-ID: 176954 [Multi-domain]  Cd Length: 498  Bit Score: 110.42  E-value: 8.25e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPF-MVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:CHL00011 233 WLPDTHGEAHYSTCMLLAGILLKMGAYGLIRINMELLPHAHSIFSPWlVIVGAIQIIYAASTSLGQRNLKKRIAYSSVSH 312

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERThsRTLLLTRNMQLALPLMGLWWLLA--SLTNMALPP 157
Cdd:CHL00011 313 MGFIIIGIGSITDTGLNGAILQIISHGFIGAALFFLAGTSYDRI--RLVYLDEMGGIAIPMPKIFTMFSsfSMASLALPG 390

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 22135004  158 TINLMGELTI---IISLFNWSN-----ITILMtGLGTLITAIYTLYML 197
Cdd:CHL00011 391 MSGFVAELIVffgIITSQKYLLmpkilITFVM-AIGMILTPIYLLSML 437
PRK02546 PRK02546
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 1-197 2.70e-23

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 235050 [Multi-domain]  Cd Length: 525  Bit Score: 97.85  E-value: 2.70e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFM-VMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:PRK02546 235 WLPDAHGEATAPVHMLLAGILLKMGGYALLRMNAGMLPDAHAQFAPLLiVLGVVNIIYAALTSFAQRNLKRKIAYSSISH 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:PRK02546 315 MGFVLIGIGSFTDLGTSGAMLQMISHGLIGASLFFLVGATYDRTHTLMLDEMGGVGQKMRKMFAMWTACSLASLALPGMS 394

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 22135004  160 NLMGELTIIISL-------FNWSNITILMTGLGTLITAIYTLYML 197
Cdd:PRK02546 395 GFVAELMVFVGFatsdaytLPFRVVVVFLAAVGVILTPIYLLSML 439
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-234 5.27e-21

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 91.19  E-value: 5.27e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMT-------LDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIA 73
Cdd:PRK12667 245 WLPDAHPAAPSPVSAMLSGLVVNVGAYAIIRFLYTifgispsLIDFRAALSPILIILGAVSAIIGALMMVVQKDVKRLLA 324

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   74 YSSVSHMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNM 153
Cdd:PRK12667 325 YSTISHMGYIFMGIGIGTQLGLAAALFHIINHAIAKSLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFAFLIGALSLV 404

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  154 ALPPTINLMGELTIIISLFNWSN-ITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSipptHTREHLLMTLHILPMAL 232
Cdd:PRK12667 405 GIPPLNGFFSKLLLFNALLESGFyLPALVLLIASAISLVGYFRAWYSLFFGKPKSGEEV----EHKESPSMSVVILVLAL 480


                 ..
gi 22135004  233 LT 234
Cdd:PRK12667 481 AV 482
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-234 6.93e-20

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 88.01  E-value: 6.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTL----DPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSS 76
Cdd:PRK08375 224 WLPRAYPAAPPVVTALLSGLVTKVAVYALIRIYFTVfggdFRFALGLGWLLAVLALLSMLVGSLAALGQDDVKRVLAYST 303

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   77 VSHMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALP 156
Cdd:PRK08375 304 VSQMGYILLGLALLTPLALAAGLLHLLHHALMKGALFLAAGAIEVTYGTRRLSELSGLGRRMPLTAAAFAVASLSLIGVP 383

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  157 PTINLMGELTIIISLF---NWSNITILMtgLGTLITAIYTLYMLTTTQWGETPSHlksIPPTHTREHLLMTLHILPMALL 233
Cdd:PRK08375 384 PTSGFVSKWYLVVGAVeagQWLVLAVLL--ASSLLALLYFLRIWYRAFFGPPPPG---SEAPKQEAPLGMLAPSLALALL 458


                 .
gi 22135004  234 T 234
Cdd:PRK08375 459 S 459
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 1-233 1.14e-19

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 87.29  E-value: 1.14e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLD--PLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVS 78
Cdd:PRK06458 236 WLPDAHSEAPSPVSALLSGVLLNVALYAVLRYYILIDaaIGSDFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIE 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   79 HMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPT 158
Cdd:PRK06458 316 HMGLIAFALGIGGPLGIFAALLHMLNHSLTKSAIFFASGNVLQKYGTRDINVIRGLLKVSPLTGWGLMLGALAIAGMPPF 395

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22135004  159 INLMGELTIIISLFN---WSNITILMTGLGTLITAIytLYMLTTTQWGEtpshlksiPPTHTREHLLMTLHILPMALL 233
Cdd:PRK06458 396 GVFISEFLILTAGLArgpLLIAILLLLLLTLAFAAL--VRRVAGMVFGE--------PPEAVNRGDLGWLTTSPMFVH 463
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
1-214 3.14e-19

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 85.92  E-value: 3.14e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPfmVMALWG---VIMTSSICLRQTDLKSLIAYSSV 77
Cdd:PRK07363 227 WLPDAYTEASPAVAILLGGVLAKLGTYGLLRFGLQLFPQTWSLVAP--GLAIIGtisVIYGALSAIAQKDIKRMVAYSSI 304

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   78 SHMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTR---NMQLALPLMGLWWLLASLTNMA 154
Cdd:PRK07363 305 GHMGYILVAAAAGTQLSLLGAVAQMISHGLILALLFHLVGIVERKVGTRDLDVLNglmNPIRGLPLTSALLVLAGMASAG 384

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  155 LPPTINLMGELTIIISLFNWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPP 214
Cdd:PRK07363 385 IPGLVGFVAEFIVFQGSFSTFPIPTLLCIVASGLTAVYFVILLNRTCFGRLDNKLAYYPK 444
PRK08377 PRK08377
NADH dehydrogenase subunit N; Validated
 1-199 6.69e-13

NADH dehydrogenase subunit N; Validated


Pssm-ID: 181406 [Multi-domain]  Cd Length: 494  Bit Score: 67.48  E-value: 6.69e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMV--MALWGVIMTSSICLRQTDLKSLIAYSSVS 78
Cdd:PRK08377 228 WAPDAYQAAPHPITVMFSAFVVKAGLYAMARILYLMQNANGWSSVLKLViiMATLTVFFAELSALRQKNVKRMIAYSSIG 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   79 HMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPT 158
Cdd:PRK08377 308 QVGMIALALALGTQAGVDAGVFHMINHAIVKALLFLAVGYVGITLGGTEIEKFEGLGKRMPLTALALTIGALSTVGIPLF 387

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 22135004  159 INLMGELTIIISLFNWSNITILMTGLG-TLITAIYTLYMLTT 199
Cdd:PRK08377 388 NVFWSKFRIILAGLSAGYTWPVALVLGaSVVEAVYYFRLIHT 429
PRK07234 PRK07234
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-189 9.45e-13

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235978 [Multi-domain]  Cd Length: 470  Bit Score: 66.90  E-value: 9.45e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVImtssICLRQTDLKSLIAYSSVSHM 80
Cdd:PRK07234 206 WLPLTHSEAEPPVSALLSGVVVKAGVFPLVRCALDVPGLDLIVRIFGVGTALLGVL----FALLEKDLKRMLAFSTISQL 281

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLtqtqwsyTGSItLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLmglwwLLASLTNMALPPTIN 160
Cdd:PRK07234 282 GFILAAPL-------VGGL-YALAHGLVKSTLFLCAGALPSRNFTELISQMLGIGKWIPL-----TMASFSIAGFPLLAG 348

                        170       180
                 ....*....|....*....|....*....
gi 22135004  161 LMGELTIIISLFNWSNITILMTGLGTLIT 189
Cdd:PRK07234 349 FVSKVLTLKNLLPWQAIALNLAAVGTAAS 377
PRK08667 PRK08667
hydrogenase membrane subunit; Validated
 1-172 1.45e-11

hydrogenase membrane subunit; Validated


Pssm-ID: 236331 [Multi-domain]  Cd Length: 644  Bit Score: 63.60  E-value: 1.45e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMtlDPLSKTLSYPF------MVMALWGVIMTssicLRQTDLKSLIAY 74
Cdd:PRK08667 227 WLPYAHPASPSNVSALMSGVMLKVAVYGLVRFLM--DVLSPELWWGVlillagSISALLGVIYA----LKEHDLKGLLAY 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   75 SSVSHMGLVIAATLTQTQWSYTGSITLM-----------IAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGL 143
Cdd:PRK08667 301 SSIENIGIILMGIGLYVIFGVYGLDTLAllalggalfhsLNHALFKSLLFLTAGSVVHATGTRNIEKMGGLVKLMPYTSA 380

                        170       180
                 ....*....|....*....|....*....
gi 22135004  144 WWLLASLTNMALPPTINLMGELTIIISLF 172
Cdd:PRK08667 381 LFLVGAVSIAALPPFNGFASELLLYESFF 409
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 1-113 5.35e-11

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 61.69  E-value: 5.35e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTL--DPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVS 78
Cdd:PRK08676 228 WLPAAYAKAPSVVSALLSGTVLNIGIYGILRLSALLrqSGAAEQFSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIE 307

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 22135004   79 HMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLF 113
Cdd:PRK08676 308 HMGLMLLGIGIGTPLALFWMLFHMLAHSLVKSGLF 342
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-234 7.43e-11

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 61.29  E-value: 7.43e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMT-----LDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYS 75
Cdd:PRK12662 231 WLIQAYSEAPSFISVFFSGTSTKVMIYLIIRIVYDvfkanFVFTTLPFNNVFMILAALAIVFGSVLAILSKDIKRIFAYS 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   76 SVSHMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANT---NYERTHSRTLLltrNMQLALPLMGLWWLLASLTN 152
Cdd:PRK12662 311 SISHIGYIILAVSLNTYYGLAAAVAYIVNHSIVKSALFMVSGSisyHFGTTKLEDCL---NLWKSMPKITLAFVLLSLSL 387

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  153 MALPPTINLMGE---LTIIISLFNWsnITILMTGLGTLITAIYTLYMLTTTQWgETPSHLKSIPPTHTREHLLMTLHILP 229
Cdd:PRK12662 388 IGMPPTSGFVAKwyiLDAFIKSNAW--IGLVVLLVGSGLSVIYVWKIVEALYF-ESRMVESKANDKAFKTPNAMVLCIWI 464


                 ....*
gi 22135004  230 MALLT 234
Cdd:PRK12662 465 MAILS 469
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 1-244 1.24e-10

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 60.78  E-value: 1.24e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIrITMTLDPLSK------------TLSYPFMVMALWGVIMTSSICLRQTDL 68
Cdd:PRK08668 218 WAPDAYSEAPQSFSAVLSGQLSKLGAYGFL-LVLYVLPGTKlfsefgtyrgvpLFNYILAWLGNISIIVGTLMAILQEDI 296

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   69 KSLIAYSSVSHMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLA 148
Cdd:PRK08668 297 KKLIAYSSVANGGYILVGLGLGTSLGFAGGLFHVFNHALFKGLFFLIFAAVIYRTGTTKISEMGGLIEKMPFTFAMYLVA 376

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  149 SLTNMALPPTINLMGELTIIISLF-NWSNITILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIppthtREHLLMTLhi 227
Cdd:PRK08668 377 IISLAGIPPMSGFASKWLIFEALIsKGMPITAFMAFFGSIGSFLYVFRPLAGVFLGQLPSDHKDV-----KEAPLPML-- 449

                        250
                 ....*....|....*..
gi 22135004  228 LPMALLTTkPELIWGTF 244
Cdd:PRK08668 450 IPMAILVL-LNVVFGVA 465
PRK06525 PRK06525
hydrogenase 4 subunit D; Validated
 1-187 1.30e-10

hydrogenase 4 subunit D; Validated


Pssm-ID: 180606 [Multi-domain]  Cd Length: 479  Bit Score: 60.76  E-value: 1.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAhVEAPIAGSMIL-AAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:PRK06525 229 WLPDA-MEAPTPASAYLhAASMVKVGVYIFARAIQSMGPIPHVIGYVGAVMAIVTLLYGFLMYLPQQDMKRLLAYSTITQ 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLV---IAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALP 156
Cdd:PRK06525 308 LGYMffgLSLAILGSRLALEGSIAYIFNHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLKKLPLVGVGFCVAALAITGVP 387

                        170       180       190
                 ....*....|....*....|....*....|.
gi 22135004  157 PTINLMGELTIIISLFNWSNITILMTGLGTL 187
Cdd:PRK06525 388 PFNGFFSKFPIFAAGFELSVEYWILLPAMVL 418
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 1-233 4.36e-10

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 59.40  E-value: 4.36e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   1 WLPKAhVEAPIAGSMIL-AAVLLKLGGYGIIRITMTLDpLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:COG1009 233 WLPDA-MEGPTPVSALLhAATMVKAGVYLLARLSPLFA-LSPVWLTVVAIIGAITALFAALIALAQTDIKRVLAYSTVSQ 310

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  80 MGLVIAATLTQtqwSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:COG1009 311 LGYMFLALGVG---AYVAALFHLLTHAFFKALLFLGAGSVIHATGTRDIRKMGGLRKKMPITAITFLIGALSLAGIPPFA 387

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 22135004 160 NLMGELTIIISLFNWSNITILMTGLGTL---ITAIYTLYMLTTTQWGETPSHLksipPTHTRE-HLLMTlhiLPMALL 233
Cdd:COG1009 388 GFFSKEAILEAALEAGGLGPLLLAVALLgafLTAFYSFRLFFLVFFGKPRPKT----PKHPHEsPWLMT---LPLVVL 458
PRK12650 PRK12650
DUF4040 family protein;
1-215 4.74e-09

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 56.20  E-value: 4.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSkTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:PRK12650 230 WLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFHDVA-VWNWLLIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQL 308

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:PRK12650 309 GWIVATIGVGTPFALTAAVVHTLAHALFKSSLFMLIGVVDHQAGTRDIRRLGSLWRRMPFTFVSVTIAALSMAAVPPLFG 388

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 22135004  161 LMGELTIIISLF-----NWSNITILMT-GLGTLITAIYTL-YMLTTTQWGETP-SHLKSIPPT 215
Cdd:PRK12650 389 FVSKEGMLTAFLeapggNAGVVLLLVGaALGAVFTFAYSArLVLGAFVDGPRDmSHVKEAPVS 451
PRK12646 PRK12646
DUF4040 family protein;
1-233 1.18e-08

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 55.15  E-value: 1.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAhVEAPIAGSMIL-AAVLLKLGGYGIIRITMTLDpLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:PRK12646 232 WLPRA-MAAPTPVSAYLhSATMVKAGIFLLFRFTPLLG-LSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQ 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLV-----IAATLTQTQWSYTGSITLMIA---------HGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWW 145
Cdd:PRK12646 310 LGMImamvgIGGGYAQHQQDAIASIYVFVLfaalfhlmnHAIFKCALFMGVGIIDHEAGTRDIRILSGMRQLFPKMNLVM 389

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  146 LLASLTNMALPPTINLMGELTIIISLFNWSNI-------TILMTGLG---TLITAIYTLYMLTTTQWGETPShlKSIPPT 215
Cdd:PRK12646 390 TIAALSMAGVPFLNGFLSKEMFLDALTQTGQLsqfslisMIIIVFIGviaSIFTFTYALYMVKEVFWGKYDS--KVFTKK 467

                        250
                 ....*....|....*...
gi 22135004  216 HTREHLLMTLHILPMALL 233
Cdd:PRK12646 468 NIHEPWLFSLPSLILMVL 485
PRK06589 PRK06589
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-234 1.63e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 235835 [Multi-domain]  Cd Length: 489  Bit Score: 54.44  E-value: 1.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFM-----VMALWGVIMTSSICLRQTDLKSLIAYS 75
Cdd:PRK06589 232 WLPAAMVAHYPVSALLHAVIVVKTGLFCIYKILLYIFGLSYLQRIFAEfnwliFIPIVSIFYSSLKALKTDNIKKILAYS 311

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   76 SVSHMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMAL 155
Cdd:PRK06589 312 TISQLSLALLSAFILTPKALGAAILHLVSHSFAKICLFYSMGSIYSLKKEDQVDKLHGTSKSFPLISFIISISSLSLIGI 391

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  156 PPTINLMGELTIIISLFNWSNIT--ILMTGLGTLITAIYTLYMLTTTQWGETPSHLKSIPPTHTREHLLMTLHILPMALL 233
Cdd:PRK06589 392 PIFSGFISKFLILLAASEQNQPWlsIIVMLVVIASSILSALYLLKILSSIYKPSLSENSFITKSLPYLMQISVITCCCAL 471


                 .
gi 22135004  234 T 234
Cdd:PRK06589 472 T 472
PRK06521 PRK06521
hydrogenase 4 subunit B; Validated
 1-157 2.20e-08

hydrogenase 4 subunit B; Validated


Pssm-ID: 235820 [Multi-domain]  Cd Length: 667  Bit Score: 54.12  E-value: 2.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSkTLSYPFMVMALWGVIMTSSI--CLRQTDLKSLIAYSSVS 78
Cdd:PRK06521 232 WLPRAHPAAPSHVSALMSGVMLKVAIYGILRVVFDLLGAP-GWWWGVLVLALGAISAVLGVlyALAEHDLKRLLAYSTIE 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   79 HMGLVI----------------AATLtqtqwSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLL----LTRNMqlal 138
Cdd:PRK06521 311 NIGIIFvglglamvfiaygmplLAAL-----ALTAALYHLLNHALFKSLLFLGAGAVLHATGTRDMEklggLIRRM---- 381

                        170
                 ....*....|....*....
gi 22135004  139 PLMGLWWLLASLTNMALPP 157
Cdd:PRK06521 382 PWTAWAFLIGCLAISALPP 400
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 1-187 3.66e-08

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 53.38  E-value: 3.66e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAhVEAPIAGSMIL-AAVLLKLGGYGIIRITMTLdplSKTLSYPFMVMALWGVIM--TSSICLRQTDLKSLIAYSSV 77
Cdd:PRK12647 217 WLPNA-MEAPTPVSAYLhSATMVKAGIYLLARLNPVL---GGTPLWQTILPLFGGLTMltGALLAVRQTDLKLILAYSTV 292

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   78 SHMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPP 157
Cdd:PRK12647 293 SALGTLVMLLGLGSELAIKAAVLFLVAHSLYKGALFMVAGIIDHETGTRDITKLGGLRRAMPITAAAALLAALSMAGLPP 372

                        170       180       190
                 ....*....|....*....|....*....|
gi 22135004  158 TINLMGELTIIISLFNWSNITILMTGLGTL 187
Cdd:PRK12647 373 LFGFLAKELIYEALLEAPLWSLILTVAAVL 402
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-234 1.65e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 51.49  E-value: 1.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFM-VMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:PRK07691 231 WLPGSYYAPPIAIAALFGALLTKVGVYAIARTFTLFFSHDTSFTHYLIlILALLTIIFGVIGAVAYFDIKKIIIYNIMIA 310

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLlltRNMQLAL---PLMGLWWLLASLTNMALP 156
Cdd:PRK07691 311 VGVILVGVAMMTESGMIGAIYYLIHDMIVKAALFLLIGIMIKITGTTDL---KKMGGLIkryPVLGWMFFIAALSLAGIP 387

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  157 PTINLMGELTIIISLFN----WSNITILMTGLGTLITAIytlYMLTTTQWGETpshlKSIPPTHTREHLLMTLHILPMAL 232
Cdd:PRK07691 388 PLSGFYGKFFIVEGTFEagfyVSGIIVLLSSLLVLYSVI---KIFLKGFWGEP----KGYDLNNKVPVKKLLLPAVVLVA 460


                 ..
gi 22135004  233 LT 234
Cdd:PRK07691 461 IT 462
ND4 MTH00062
NADH dehydrogenase subunit 4; Provisional
 1-180 2.39e-07

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214413 [Multi-domain]  Cd Length: 417  Bit Score: 50.69  E-value: 2.39e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSkTLSYPFMVMALWGVIMTSSicLRQTDLKSLIAYSSVSHM 80
Cdd:MTH00062 187 WLPIVHAEASSPVSIFLSGYIMKLGLLGVYRFCGFIFSGS-FLGYLFLCCLFSVFFLITA--CSELDGKRWLAFLSLSHI 263

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 gLVIAATLTQTQWSYTG-SITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:MTH00062 264 -LVPVLGLFVGDWSSINlSFFYCLGHGLSAGLVFLLLWCFYEVSGSRNWVLLKSGINGSLVLRVIVVFSFLSLCSFPPTI 342

                        170       180
                 ....*....|....*....|.
gi 22135004  160 NLMGELTIIISLFNWSNITIL 180
Cdd:MTH00062 343 QFFCEVFLVSSSFGVLVYLLF 363
PRK12663 PRK12663
Na+/H+ antiporter subunit D;
1-234 2.84e-07

Na+/H+ antiporter subunit D;


Pssm-ID: 237163 [Multi-domain]  Cd Length: 497  Bit Score: 50.72  E-value: 2.84e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRI-TMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:PRK12663 228 WLPAAYHTPNTEVAALFAALLTKVGIYALIRVfTLLFPQERELLHPLLATMAAITMVIGALGALAYKDIRRIAGYQVISS 307

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTI 159
Cdd:PRK12663 308 IGFILLGLALGTPAGINGAIFYLVHDMVVKTALFLIAGSLVRLTGYRSLQYLGGLYRKEPLFGALFLILIFAIGGLPPFS 387

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 22135004  160 NLMGELTIIISLFNWSNITILMTglgTLITAIYTLYMLT----TTQWGETPSHLKSIPPTHTREhllmtlhILPMALLT 234
Cdd:PRK12663 388 GFWGKVLLVQGALDNGAYILLAL---MLITSLITMYSLFriffLAYWGDKDGEEVNFKPIPLYR-------KLPLSILA 456
PRK12665 PRK12665
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-168 1.85e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237165 [Multi-domain]  Cd Length: 521  Bit Score: 48.43  E-value: 1.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPlSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:PRK12665 231 WLPDSYPTAPAPVTAVFAGLLTKVGVYAIIRTHTLLFP-GGGLDTLLMVVALLTMVVGILGAIAQSDIKRLLSFTLVSHI 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPPTIN 160
Cdd:PRK12665 310 GYMVFGIALSTVAGLSGAIYYVAHHITVQTTLFLVVGLIERQAGSSSLRRLGGLAKASPLLAVLFFVPALNLGGIPPFSG 389


                 ....*...
gi 22135004  161 LMGELTII 168
Cdd:PRK12665 390 FIGKVALL 397
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 1-203 1.17e-05

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 46.07  E-value: 1.17e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAhVEAPIAGSMIL-AAVLLKLGGYGIIRITmtlDPLSKTLSYPFMVMALWGVIMTSS--ICLRQTDLKSLIAYSSV 77
Cdd:PRK12644 225 WLPGA-MAAPTPVSAYLhAAAMVKAGIYLVARLA---PGFADVPVWRPTVLVLGLATMLLGgwRALRQHDLKLILAYGTV 300

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   78 SHMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALPP 157
Cdd:PRK12644 301 SQLGFLTVLVGIGTRDAALAGLAMLLAHALFKAALFLVVGIIDHSTGTRDIRKLSGLGRRQPVLAVVAALAAASMAGLPP 380

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 22135004  158 TINLMGELTIIISLFN------WSNITILMTGLGTLITAIYTLYMLtttqWG 203
Cdd:PRK12644 381 LLGFVAKEAALEAVLHdgalgpAGPVVLAGIVLGSILTVAYSLRFL----WG 428
PRK06459 PRK06459
hydrogenase 4 subunit B; Validated
 1-189 1.42e-05

hydrogenase 4 subunit B; Validated


Pssm-ID: 235806 [Multi-domain]  Cd Length: 585  Bit Score: 45.55  E-value: 1.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITM-TLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSH 79
Cdd:PRK06459 182 WLPIAHGNAPSNFSAILSATMTLMGVYGILKMTIlTQTIPIGYFGLTILAIGAFSILFGALYAYVSENVKGLLAFSTIEN 261

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   80 MGLVIAAT----LTQTQWSYTGSITLM------IAHGLTSSMLFCLANTnyerTHSRTLLLTRNMQLALPLMGLWWLLAS 149
Cdd:PRK06459 262 NGAILVALglymVTKQLITSIEHFSLItvilysFAHSVAKTGLFLSSGL----QEKQSITYSKKIRNRWIELGLTLLASS 337

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 22135004  150 LTnmALPPTINLMGELTIIISLFNWSNITILMTGLGTLIT 189
Cdd:PRK06459 338 LS--GLLPNIGGVASWLLLESLFMFAYVLHNVISILFIVT 375
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
1-109 1.49e-05

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 45.58  E-value: 1.49e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLlKLGGYGII-RITMT-LDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVS 78
Cdd:PRK05777 226 WTPDVYEGAPTPVTAFLATAP-KIAAFAVLlRLLVVaFGGLSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIA 304

                         90       100       110
                 ....*....|....*....|....*....|.
gi 22135004   79 HMGLVIAATLTQTQWSYTGSITLMIAHGLTS 109
Cdd:PRK05777 305 HAGYLLVGLAAGTAEGYSAVLFYLLAYLFMT 335
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-157 1.50e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 45.47  E-value: 1.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILaaVLLKLGG-YGIIRITMTLDPLS---KTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSS 76
Cdd:PRK08376 242 WLPDAYPAAPSSISAML--LVIKQAGlYALARVLFSIYGPAinlATVGWVIIILGCLTMFVGVAMAVVQKDVKRLLAYHS 319

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   77 VSHMGLVI------AATLTQTQWSYTGSITL------MIAHGLTSSMLFCLANTNYERTHSRTLL----LTRNMqlalPL 140
Cdd:PRK08376 320 VSQIGYMLlglgvgLAALGDPAMASYGEIALaggiyhIVNHALYKALLFLTAGAVIYETGTRNLNelggLARTM----PK 395

                        170
                 ....*....|....*..
gi 22135004  141 MGLWWLLASLTNMALPP 157
Cdd:PRK08376 396 TTIAFLIGAAAIVGLPP 412
PRK08042 PRK08042
formate hydrogenlyase subunit 3; Reviewed
 1-176 1.63e-05

formate hydrogenlyase subunit 3; Reviewed


Pssm-ID: 181206 [Multi-domain]  Cd Length: 593  Bit Score: 45.59  E-value: 1.63e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAHVEAPIAGSMILAAVLLKLGGYGIIRITMTLDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVSHM 80
Cdd:PRK08042 202 WVPQAHANASAPAAALFSTVVMKIGLLGILTLSLLGGNAPLWWGVALLVLGMITAFVGGLYALMEHNIQRLLAYHTLENI 281

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   81 GLV---IAATLTQTQWS--------YTGSITLMIAHGLTSSMLFCLANTNYERTHSRTLLLTRNMQLALPLMGLWWLLAS 149
Cdd:PRK08042 282 GIIllgLGAGVTGIALEqpalialgLVGGLYHLLNHSLFKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGL 361

                        170       180
                 ....*....|....*....|....*..
gi 22135004  150 LTNMALPPTINLMGELTIIISLFNWSN 176
Cdd:PRK08042 362 MAMAALPPLNGFAGEWVIYQSFFKLSN 388
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 1-109 2.34e-05

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 44.72  E-value: 2.34e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   1 WLPKAHVEAPIAGSMILAAVLlKLGGYGI-IRITMT-LDPLSKTLSYPFMVMA----LWGVIMTssicLRQTDLKSLIAY 74
Cdd:COG1007 225 WTPDVYEGAPTPVTAFLATAP-KIAAFAAlLRLLVEaFPGLAADWQLLLAVLAvlsmTVGNLAA----LAQTNVKRMLAY 299

                        90       100       110
                ....*....|....*....|....*....|....*
gi 22135004  75 SSVSHMGLVIAATLTQTQWSYTGSITLMIAHGLTS 109
Cdd:COG1007 300 SSIAHAGYLLLGLAAGTPLGVSAALFYLLAYLFMN 334
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 39-196 2.70e-05

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 44.49  E-value: 2.70e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   39 LSKTLSYPFMVMALWGVIMTSSIC-----LRQTDLKSLIAYSSVSHMGLVIAATLtqtqWSYTGSITLMIAHGLTS-SML 112
Cdd:MTH00144 134 LSNFLDLYWLAYLLCVISVLSALVgsiggLNQTQVRALLAYSSISHTGWMLVAIL----HGSWLMWMYFLIYIVSSgFLF 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  113 FCLANTNYerthsrTLLLTRNMQLALPLMGLWWLLASLTNMALPPTINLMGELTIIISLFNWS-NITILMTGLGTLITAI 191
Cdd:MTH00144 210 FSLWSGDS------GSMKDLGSLKPSYKTGLSIISLLLSLGGLPPFLGFCSKLLVLISSMESSpLLLILLLLLGSLISLF 283


                 ....*
gi 22135004  192 YTLYM 196
Cdd:MTH00144 284 FYLSV 288
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 1-197 4.57e-04

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 41.09  E-value: 4.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004     1 WLPKAHVEAPIAGSMILAAVLlKLGGYGI-IRITMT-LDPLSKTLSYPFMVMALWGVIMTSSICLRQTDLKSLIAYSSVS 78
Cdd:TIGR01770 225 WVPDVYEGAPTPVTAFFSIVP-KIAIFAVfLRLFLYiLFGFSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSIS 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    79 HMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLF-CLANT-NYERTHSRTLLLTRNMQLALPLMGLWWLLASLTNMALP 156
Cdd:TIGR01770 304 HVGYILIGLLAGTLEGIKAVLFYIFIYALMSLGAFgVLSLLrSYKDEWIEYISDFAGLFKTNPILAILILIFMFSLAGIP 383

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 22135004   157 PTINLMGELTIIISLFNwsNITILMTGLGTLITAIYTLYML 197
Cdd:TIGR01770 384 PLAGFFGKFYVFFALLK--SGLYWLAVIAVLTSVIGAFYYL 422
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
48-157 8.48e-04

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 40.01  E-value: 8.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   48 MVMALWGVIMTSSICLRQTDLKSLIAYSSVSHMGLVIAATLTQTQWSYTGSITLMIAHGLTSSMLFCLANTNYERTHSRT 127
Cdd:PRK06277 270 IALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAINHVIYKSALFLGAGIVSYRTKTSN 349

                         90       100       110
                 ....*....|....*....|....*....|
gi 22135004  128 LLLTRNMQLALPLMGLWWLLASLTNMALPP 157
Cdd:PRK06277 350 LRKLGGLLPVMPVVAFMVLCAKLAISGVPP 379
ND5 MTH00020
NADH dehydrogenase subunit 5; Reviewed
 1-113 2.59e-03

NADH dehydrogenase subunit 5; Reviewed


Pssm-ID: 214400 [Multi-domain]  Cd Length: 610  Bit Score: 38.52  E-value: 2.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004    1 WLPKAhVEAPIAGS-MILAAVLLKLGGYGIIRITmtldPLSKTLSYPFMVMALWG---VIMTSSICLRQTDLKSLIAYSS 76
Cdd:MTH00020 232 WLPDA-MEGPTPVSaLIHAATMVTAGVFLLIRSS----PLFEQAPLALIIVTIVGsltVFFAATVGLVQNDLKKVIAYST 306

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 22135004   77 VSHMG-LVIAATLTQtqwsYTGSITLMIAHGLTSSMLF 113
Cdd:MTH00020 307 CSQLGyMVVACGLSH----YSISLFHLMNHAFFKALLF 340
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 32-197 2.70e-03

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 38.22  E-value: 2.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004   32 ITMTLDPLSKTLSYPFMVMAlwGVIMTSSICLRQTDLKSLIAYSSVSHMGLViaaTLTQTQWSYTGSITLMIAHGLTSSM 111
Cdd:MTH00011 137 ILFFFTSHNILPMMTSMAAM--SALAGGLGGMNQTQLRPLLAYSSIGHMGWM---TMISVFSPSMAILYFMTYIIITTPL 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 22135004  112 LFCLANTNYERTHSRTLLLTRNmqlalPLMGLWWLLASLTNMALPPTINLMGELTIIISLFNWSNITILMTGL-GTLITA 190
Cdd:MTH00011 212 MLLFAYLNAFSTKFNSKISSMS-----QTTSMSLFIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIvGSLMNL 286


                 ....*..
gi 22135004  191 IYTLYML 197
Cdd:MTH00011 287 FYYLNLI 293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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