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Conserved domains on  [gi|221046176|dbj|BAH14765|]
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unnamed protein product [Homo sapiens]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
2-276 1.81e-29

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 115.01  E-value: 1.81e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176   2 KIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASR 81
Cdd:COG2319  145 RLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSA 224

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176  82 DGTARLWDCGRSACLGVLADCGSSINGVAVgaadnsinlgSPeqmpserevgtEAKMLLLAREDKKLQCLGLQSRQLVFL 161
Cdd:COG2319  225 DGTVRLWDLATGKLLRTLTGHSGSVRSVAF----------SP-----------DGRLLASGSADGTVRLWDLATGELLRT 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176 162 FIG-SDAFNCCTFL-SGFLLLAGTQDGNIYQLDVRSPRaPVQVIHRSGAPVLSLLSVRDG-FIASQG-DGSCFIVQ-QDL 236
Cdd:COG2319  284 LTGhSGGVNSVAFSpDGKLLASGSDDGTVRLWDLATGK-LLRTLTGHTGAVRSVAFSPDGkTLASGSdDGTVRLWDlATG 362

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 221046176 237 DYVTELTGADcDPVYKVATW--EKQIYTCCRDGLVRRYQLSD 276
Cdd:COG2319  363 ELLRTLTGHT-GAVTSVAFSpdGRTLASGSADGTVRLWDLAT 403
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
2-276 1.81e-29

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 115.01  E-value: 1.81e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176   2 KIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASR 81
Cdd:COG2319  145 RLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSA 224

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176  82 DGTARLWDCGRSACLGVLADCGSSINGVAVgaadnsinlgSPeqmpserevgtEAKMLLLAREDKKLQCLGLQSRQLVFL 161
Cdd:COG2319  225 DGTVRLWDLATGKLLRTLTGHSGSVRSVAF----------SP-----------DGRLLASGSADGTVRLWDLATGELLRT 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176 162 FIG-SDAFNCCTFL-SGFLLLAGTQDGNIYQLDVRSPRaPVQVIHRSGAPVLSLLSVRDG-FIASQG-DGSCFIVQ-QDL 236
Cdd:COG2319  284 LTGhSGGVNSVAFSpDGKLLASGSDDGTVRLWDLATGK-LLRTLTGHTGAVRSVAFSPDGkTLASGSdDGTVRLWDlATG 362

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 221046176 237 DYVTELTGADcDPVYKVATW--EKQIYTCCRDGLVRRYQLSD 276
Cdd:COG2319  363 ELLRTLTGHT-GAVTSVAFSpdGRTLASGSADGTVRLWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 1-223 3.08e-26

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 103.95  E-value: 3.08e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176   1 MKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSAS 80
Cdd:cd00200   33 IKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSS 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176  81 RDGTARLWDCGRSACLGVLADCGSSINGVAV---------GAADNSINLGSPEqmpSEREVGT---------------EA 136
Cdd:cd00200  113 RDKTIKVWDVETGKCLTTLRGHTDWVNSVAFspdgtfvasSSQDGTIKLWDLR---TGKCVATltghtgevnsvafspDG 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176 137 KMLLLAREDKKLQCLGLQSRQLVFLFIG-SDAFNCCTFL-SGFLLLAGTQDGNIYQLDVRSPRaPVQVIHRSGAPVLSLL 214
Cdd:cd00200  190 EKLLSSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSpDGYLLASGSEDGTIRVWDLRTGE-CVQTLSGHTNSVTSLA 268

                        250
                 ....*....|
gi 221046176 215 SVRDG-FIAS 223
Cdd:cd00200  269 WSPDGkRLAS 278
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 8-47 6.52e-07

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 45.00  E-value: 6.52e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 221046176     8 NGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWS 47
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
52-89 2.37e-06

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 43.49  E-value: 2.37e-06
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 221046176   52 SCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWD 89
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
2-276 1.81e-29

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 115.01  E-value: 1.81e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176   2 KIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASR 81
Cdd:COG2319  145 RLWDLATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSA 224

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176  82 DGTARLWDCGRSACLGVLADCGSSINGVAVgaadnsinlgSPeqmpserevgtEAKMLLLAREDKKLQCLGLQSRQLVFL 161
Cdd:COG2319  225 DGTVRLWDLATGKLLRTLTGHSGSVRSVAF----------SP-----------DGRLLASGSADGTVRLWDLATGELLRT 283

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176 162 FIG-SDAFNCCTFL-SGFLLLAGTQDGNIYQLDVRSPRaPVQVIHRSGAPVLSLLSVRDG-FIASQG-DGSCFIVQ-QDL 236
Cdd:COG2319  284 LTGhSGGVNSVAFSpDGKLLASGSDDGTVRLWDLATGK-LLRTLTGHTGAVRSVAFSPDGkTLASGSdDGTVRLWDlATG 362

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 221046176 237 DYVTELTGADcDPVYKVATW--EKQIYTCCRDGLVRRYQLSD 276
Cdd:COG2319  363 ELLRTLTGHT-GAVTSVAFSpdGRTLASGSADGTVRLWDLAT 403
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 1-223 3.08e-26

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 103.95  E-value: 3.08e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176   1 MKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSAS 80
Cdd:cd00200   33 IKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTLTGHTSYVSSVAFSPDGRILSSSS 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176  81 RDGTARLWDCGRSACLGVLADCGSSINGVAV---------GAADNSINLGSPEqmpSEREVGT---------------EA 136
Cdd:cd00200  113 RDKTIKVWDVETGKCLTTLRGHTDWVNSVAFspdgtfvasSSQDGTIKLWDLR---TGKCVATltghtgevnsvafspDG 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176 137 KMLLLAREDKKLQCLGLQSRQLVFLFIG-SDAFNCCTFL-SGFLLLAGTQDGNIYQLDVRSPRaPVQVIHRSGAPVLSLL 214
Cdd:cd00200  190 EKLLSSSSDGTIKLWDLSTGKCLGTLRGhENGVNSVAFSpDGYLLASGSEDGTIRVWDLRTGE-CVQTLSGHTNSVTSLA 268

                        250
                 ....*....|
gi 221046176 215 SVRDG-FIAS 223
Cdd:cd00200  269 WSPDGkRLAS 278
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 11-231 2.52e-23

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 96.25  E-value: 2.52e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176  11 LRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDC 90
Cdd:cd00200    1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176  91 GRSACLGVLADCGSSINGVAVgaadnsinlgspeqMPSERevgteakMLLLAREDKKLQCLGLQSRQLVFLFIG-SDAFN 169
Cdd:cd00200   81 ETGECVRTLTGHTSYVSSVAF--------------SPDGR-------ILSSSSRDKTIKVWDVETGKCLTTLRGhTDWVN 139

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 221046176 170 CCTFL-SGFLLLAGTQDGNIYQLDVRSPRaPVQVIHRSGAPVLSLLSVRDG--FIASQGDGSCFI 231
Cdd:cd00200  140 SVAFSpDGTFVASSSQDGTIKLWDLRTGK-CVATLTGHTGEVNSVAFSPDGekLLSSSSDGTIKL 203
WD40 COG2319
WD40 repeat [General function prediction only];
2-276 3.05e-19

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 86.50  E-value: 3.05e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176   2 KIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASR 81
Cdd:COG2319   61 LLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSA 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176  82 DGTARLWDCGRSACLGVLADCGSSINGVA---------VGAADNSI---NLGSPEQMPS----EREVGTEA-----KMLL 140
Cdd:COG2319  141 DGTVRLWDLATGKLLRTLTGHSGAVTSVAfspdgkllaSGSDDGTVrlwDLATGKLLRTltghTGAVRSVAfspdgKLLA 220

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176 141 LAREDKKLQCLGLQSRQLVFLFIG-SDAFNCCTFLS-GFLLLAGTQDGNIYQLDVRSPRaPVQVIHRSGAPVLSLLSVRD 218
Cdd:COG2319  221 SGSADGTVRLWDLATGKLLRTLTGhSGSVRSVAFSPdGRLLASGSADGTVRLWDLATGE-LLRTLTGHSGGVNSVAFSPD 299

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 221046176 219 G-FIASQG-DGSCFIVQ-QDLDYVTELTGADcDPVYKVA--TWEKQIYTCCRDGLVRRYQLSD 276
Cdd:COG2319  300 GkLLASGSdDGTVRLWDlATGKLLRTLTGHT-GAVRSVAfsPDGKTLASGSDDGTVRLWDLAT 361
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 1-89 4.41e-16

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 76.22  E-value: 4.41e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176   1 MKIWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSAS 80
Cdd:cd00200  201 IKLWDLSTGKCLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLAWSPDGKRLASGS 280


                 ....*....
gi 221046176  81 RDGTARLWD 89
Cdd:cd00200  281 ADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
3-276 2.53e-13

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 69.17  E-value: 2.53e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176   3 IWQASNGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRD 82
Cdd:COG2319   20 LLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASAD 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176  83 GTARLWDCGRSACLGVLADCGSSINGVAV---------GAADNSI---NLGSPEQMPSEREVGTEA---------KMLLL 141
Cdd:COG2319  100 GTVRLWDLATGLLLRTLTGHTGAVRSVAFspdgktlasGSADGTVrlwDLATGKLLRTLTGHSGAVtsvafspdgKLLAS 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221046176 142 AREDKKLQCLGLQSRQLVFLFIG-SDAFNCCTFLS-GFLLLAGTQDGNIYQLDVRSPRaPVQVIHRSGAPVLSLLSVRDG 219
Cdd:COG2319  180 GSDDGTVRLWDLATGKLLRTLTGhTGAVRSVAFSPdGKLLASGSADGTVRLWDLATGK-LLRTLTGHSGSVRSVAFSPDG 258

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 221046176 220 -FIAS-QGDGSCFIVQ-QDLDYVTELTGADcDPVYKVAtW---EKQIYTCCRDGLVRRYQLSD 276
Cdd:COG2319  259 rLLASgSADGTVRLWDlATGELLRTLTGHS-GGVNSVA-FspdGKLLASGSDDGTVRLWDLAT 319
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 8-47 6.52e-07

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 45.00  E-value: 6.52e-07
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 221046176     8 NGELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWS 47
Cdd:smart00320   1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 52-89 7.78e-07

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 45.00  E-value: 7.78e-07
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 221046176    52 SCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWD 89
Cdd:smart00320   3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 pfam00400
WD domain, G-beta repeat;
52-89 2.37e-06

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 43.49  E-value: 2.37e-06
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 221046176   52 SCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWD 89
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 pfam00400
WD domain, G-beta repeat;
9-47 5.42e-06

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 42.33  E-value: 5.42e-06
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 221046176    9 GELRRVLEGHVFDVNCCRFFPSGLVVLSGGMDAQLKIWS 47
Cdd:pfam00400   1 GKLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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