|
Name |
Accession |
Description |
Interval |
E-value |
| AMP_deaminase |
pfam19326 |
AMP deaminase; |
1-536 |
0e+00 |
|
AMP deaminase;
Pssm-ID: 437158 [Multi-domain] Cd Length: 622 Bit Score: 986.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 1 MQGGILFVYDNKKMLEHqephSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSN 80
Cdd:pfam19326 92 MQDGVVHVYANKDALED----SLPYPDLRDFYTDLEHLLALIADGPIKTFCHRRLQYLESKFNLHLMLNEMKELKAQKSN 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 81 PHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTF 160
Cdd:pfam19326 168 PHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLKLTGYDLSVDTLDVHADRDTF 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 161 HRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVY 240
Cdd:pfam19326 248 HRFDKFNLKYNPIGESRLREIFLKTDNYINGRYLAEITKEVFSDLEESKYQMAEYRISIYGRSPDEWDKLASWIVDNKVY 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 241 SPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSdKSPN 320
Cdd:pfam19326 328 SPNVRWLIQVPRLYDIYKKKGIVPSFQKMLENIFLPLFEATVNPQSHPELHVFLKRVIGFDSVDDESKPERRMFR-KSPK 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 321 PDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYY 400
Cdd:pfam19326 407 PALWTNEQNPPYSYYLYYMYANIAVLNSLRKERGFNTFVLRPHCGEAGDIDHLVSAFLLAHGISHGILLRKSPVLQYLYY 486
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 401 LAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARNSVLQ 480
Cdd:pfam19326 487 LAQIGIAMSPLSNNSLFLEYHKNPFPEFFKRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSACDMCELARNSVLQ 566
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 221040010 481 SGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKS 536
Cdd:pfam19326 567 SGFSHQLKSHWLGKDYYKEGPEGNDIRRTNVPDIRVAYRYETLCQELALISDAVKS 622
|
|
| AMP_deaminase |
TIGR01429 |
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein ... |
1-530 |
0e+00 |
|
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein involved in energy metabolism. Most members of the family have an additional, poorly alignable region of 150 amino acids or more N-terminal to the region included in the model.
Pssm-ID: 273618 [Multi-domain] Cd Length: 611 Bit Score: 953.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 1 MQGGILFVYDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSN 80
Cdd:TIGR01429 82 MHGGVLFVYDNDTMLERQEPHFLVPPTLETYYVDMEHLLALISDGPTKSFCFRRLQYLESKFNLHELLNEMSELKEQKSV 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 81 PHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTF 160
Cdd:TIGR01429 162 PHRDFYNVRKVDTHIHAAASMNQKHLLRFIKHKLKTEPDETVIERDGKKLTLREVFDSLHLDPYDLSVDTLDVHADRNTF 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 161 HRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVY 240
Cdd:TIGR01429 242 HRFDKFNLKYNPVGESRLREIFLKTDNYIGGKYFAELVKEVFTDLEDSKYQYAEPRLSIYGRSPKEWDSLARWIIDHDVF 321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 241 SPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPN 320
Cdd:TIGR01429 322 SPNVRWLIQVPRLYDVYRSKKLVPNFGDMLENVFLPLFEVTKDPSSHPELHLFLQQVTGFDSVDDESKHEDHMFSRKFPS 401
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 321 PDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYY 400
Cdd:TIGR01429 402 PDEWTSEQNPPYSYYLYYMYANIMVLNNFRRERGLNTFLLRPHCGEAGSVDHLVSAFLTSHGINHGILLRKVPVLQYLYY 481
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 401 LAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARNSVLQ 480
Cdd:TIGR01429 482 LTQIPIAMSPLSNNSLFLEYSKNPLPEYLHKGLNVSLSTDDPLQFHYTKEALMEEYAIAAQVWKLSTCDMCELARNSVLQ 561
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 221040010 481 SGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFL 530
Cdd:TIGR01429 562 SGFEHQVKQHWLGPNYYKEGPEGNDIRRTNVPDIRVAFRYETLCNELSLL 611
|
|
| AMPD |
cd01319 |
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at ... |
31-527 |
0e+00 |
|
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway.
Pssm-ID: 238644 Cd Length: 496 Bit Score: 878.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 31 YTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFI 110
Cdd:cd01319 1 FYLDLEFLLALISDGPAKSFCYRRLQYLESKFQLHVLLNEDRELKEQKTVPHRDFYNVRKVDTHVHHSACMNQKHLLRFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 111 KHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLG 190
Cdd:cd01319 81 KKKLRTEPDEVVIFRDGKKLTLKEVFDSLKLTAYDLSVDTLDVHADRNTFHRFDKFNLKYNPIGESRLREIFLKTDNYIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 191 GEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKML 270
Cdd:cd01319 161 GRYLAEITKEVFSDLEESKYQHAEYRLSIYGRSKDEWDKLASWVVDNDLFSPNVRWLIQIPRLYDVYKKSGIVNSFQEML 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 271 ENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKhSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLR 350
Cdd:cd01319 241 ENIFEPLFEATKDPSSHPELHVFLQQVIGFDSVDDESK-SERRFTRKFPKPEEWTSEENPPYSYYLYYMYANITTLNSFR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 351 RERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLH 430
Cdd:cd01319 320 KARGFNTFVLRPHCGEAGDIDHLASAFLLAHGISHGINLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLSYEKNPFPEFFK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 431 KGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTN 510
Cdd:cd01319 400 RGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSTCDMCELARNSVLQSGFEHSIKRHWLGPNYLKRGVAGNDIRRTN 479
|
490
....*....|....*..
gi 221040010 511 VAQIRMAFRYETLCNEL 527
Cdd:cd01319 480 VPQIRMAYRYETLCEEL 496
|
|
| PLN02768 |
PLN02768 |
AMP deaminase |
1-539 |
0e+00 |
|
AMP deaminase
Pssm-ID: 215411 Cd Length: 835 Bit Score: 674.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 1 MQGGILFVYDNKkmleHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSN 80
Cdd:PLN02768 298 MQDGVVHVYANK----DSKEELFPVADATTFFTDLHHILRVIAAGNIRTLCHHRLNLLEQKFNLHLMLNADREFLAQKSA 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 81 PHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTF 160
Cdd:PLN02768 374 PHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGTYLTLKEVFESLDLTGYDLNVDLLDVHADKSTF 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 161 HRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVY 240
Cdd:PLN02768 454 HRFDKFNLKYNPCGQSRLREIFLKQDNLIQGRFLAELTKQVFSDLEASKYQMAEYRISIYGRKQSEWDQLASWIVNNELY 533
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 241 SPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK----HSDHMfsd 316
Cdd:PLN02768 534 SENVVWLIQLPRLYNVYKEMGIVTSFQNILDNIFIPLFEVTVDPDSHPQLHVFLKQVVGLDLVDDESKperrPTKHM--- 610
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 317 ksPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQ 396
Cdd:PLN02768 611 --PTPAQWTNVFNPAFSYYVYYCYANLYTLNKLRESKGMTTIKFRPHSGEAGDIDHLAATFLTCHNIAHGINLRKSPVLQ 688
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 397 YLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARN 476
Cdd:PLN02768 689 YLYYLAQIGLAMSPLSNNSLFLDYHRNPFPMFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVWKLSSCDLCEIARN 768
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 221040010 477 SVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELS--FLSDAMKSEEI 539
Cdd:PLN02768 769 SVYQSGFSHALKSHWIGKEYYKRGPDGNDIHKTNVPHIRVEFRDTIWKEEMQqvYLGKAKIPEEV 833
|
|
| Add |
COG1816 |
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the ... |
351-494 |
5.58e-19 |
|
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 441421 Cd Length: 326 Bit Score: 87.83 E-value: 5.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 351 RERGLstfLFRPHCGEAGSITHLVSA--FLTADNISHGLLLKKSPVLqyLYYLA--QIPIAMSPLSNNSL--FLEYSKNP 424
Cdd:COG1816 178 REAGL---HLTAHAGEAGGPESIWEAldLLGAERIGHGVRAIEDPAL--VARLAdrGIPLEVCPTSNVQLgvVPSLAEHP 252
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 425 LREFLHKGLHVSLSTDDPMQFHyTkeTLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQ 494
Cdd:COG1816 253 LRRLLDAGVRVTLNTDDPLYFG-T--TLTDEYELAAEAFGLSDADLAQLARNAIEASFLPEEEKAALLAE 319
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AMP_deaminase |
pfam19326 |
AMP deaminase; |
1-536 |
0e+00 |
|
AMP deaminase;
Pssm-ID: 437158 [Multi-domain] Cd Length: 622 Bit Score: 986.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 1 MQGGILFVYDNKKMLEHqephSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSN 80
Cdd:pfam19326 92 MQDGVVHVYANKDALED----SLPYPDLRDFYTDLEHLLALIADGPIKTFCHRRLQYLESKFNLHLMLNEMKELKAQKSN 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 81 PHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTF 160
Cdd:pfam19326 168 PHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLKLTGYDLSVDTLDVHADRDTF 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 161 HRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVY 240
Cdd:pfam19326 248 HRFDKFNLKYNPIGESRLREIFLKTDNYINGRYLAEITKEVFSDLEESKYQMAEYRISIYGRSPDEWDKLASWIVDNKVY 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 241 SPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSdKSPN 320
Cdd:pfam19326 328 SPNVRWLIQVPRLYDIYKKKGIVPSFQKMLENIFLPLFEATVNPQSHPELHVFLKRVIGFDSVDDESKPERRMFR-KSPK 406
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 321 PDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYY 400
Cdd:pfam19326 407 PALWTNEQNPPYSYYLYYMYANIAVLNSLRKERGFNTFVLRPHCGEAGDIDHLVSAFLLAHGISHGILLRKSPVLQYLYY 486
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 401 LAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARNSVLQ 480
Cdd:pfam19326 487 LAQIGIAMSPLSNNSLFLEYHKNPFPEFFKRGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSACDMCELARNSVLQ 566
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 221040010 481 SGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKS 536
Cdd:pfam19326 567 SGFSHQLKSHWLGKDYYKEGPEGNDIRRTNVPDIRVAYRYETLCQELALISDAVKS 622
|
|
| AMP_deaminase |
TIGR01429 |
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein ... |
1-530 |
0e+00 |
|
AMP deaminase; This model describes AMP deaminase, a large, well-conserved eukaryotic protein involved in energy metabolism. Most members of the family have an additional, poorly alignable region of 150 amino acids or more N-terminal to the region included in the model.
Pssm-ID: 273618 [Multi-domain] Cd Length: 611 Bit Score: 953.13 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 1 MQGGILFVYDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSN 80
Cdd:TIGR01429 82 MHGGVLFVYDNDTMLERQEPHFLVPPTLETYYVDMEHLLALISDGPTKSFCFRRLQYLESKFNLHELLNEMSELKEQKSV 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 81 PHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTF 160
Cdd:TIGR01429 162 PHRDFYNVRKVDTHIHAAASMNQKHLLRFIKHKLKTEPDETVIERDGKKLTLREVFDSLHLDPYDLSVDTLDVHADRNTF 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 161 HRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVY 240
Cdd:TIGR01429 242 HRFDKFNLKYNPVGESRLREIFLKTDNYIGGKYFAELVKEVFTDLEDSKYQYAEPRLSIYGRSPKEWDSLARWIIDHDVF 321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 241 SPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPN 320
Cdd:TIGR01429 322 SPNVRWLIQVPRLYDVYRSKKLVPNFGDMLENVFLPLFEVTKDPSSHPELHLFLQQVTGFDSVDDESKHEDHMFSRKFPS 401
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 321 PDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYY 400
Cdd:TIGR01429 402 PDEWTSEQNPPYSYYLYYMYANIMVLNNFRRERGLNTFLLRPHCGEAGSVDHLVSAFLTSHGINHGILLRKVPVLQYLYY 481
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 401 LAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARNSVLQ 480
Cdd:TIGR01429 482 LTQIPIAMSPLSNNSLFLEYSKNPLPEYLHKGLNVSLSTDDPLQFHYTKEALMEEYAIAAQVWKLSTCDMCELARNSVLQ 561
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 221040010 481 SGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFL 530
Cdd:TIGR01429 562 SGFEHQVKQHWLGPNYYKEGPEGNDIRRTNVPDIRVAFRYETLCNELSLL 611
|
|
| AMPD |
cd01319 |
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at ... |
31-527 |
0e+00 |
|
AMP deaminase (AMPD) catalyzes the hydrolytic deamination of adensosine monophosphate (AMP) at position 6 of the adenine nucleotide ring. AMPD is a diverse and highly regulated eukaryotic key enzyme of the adenylate catabolic pathway.
Pssm-ID: 238644 Cd Length: 496 Bit Score: 878.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 31 YTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFI 110
Cdd:cd01319 1 FYLDLEFLLALISDGPAKSFCYRRLQYLESKFQLHVLLNEDRELKEQKTVPHRDFYNVRKVDTHVHHSACMNQKHLLRFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 111 KHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLG 190
Cdd:cd01319 81 KKKLRTEPDEVVIFRDGKKLTLKEVFDSLKLTAYDLSVDTLDVHADRNTFHRFDKFNLKYNPIGESRLREIFLKTDNYIN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 191 GEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKML 270
Cdd:cd01319 161 GRYLAEITKEVFSDLEESKYQHAEYRLSIYGRSKDEWDKLASWVVDNDLFSPNVRWLIQIPRLYDVYKKSGIVNSFQEML 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 271 ENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKhSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLR 350
Cdd:cd01319 241 ENIFEPLFEATKDPSSHPELHVFLQQVIGFDSVDDESK-SERRFTRKFPKPEEWTSEENPPYSYYLYYMYANITTLNSFR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 351 RERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLH 430
Cdd:cd01319 320 KARGFNTFVLRPHCGEAGDIDHLASAFLLAHGISHGINLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLSYEKNPFPEFFK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 431 KGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTN 510
Cdd:cd01319 400 RGLNVSLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSTCDMCELARNSVLQSGFEHSIKRHWLGPNYLKRGVAGNDIRRTN 479
|
490
....*....|....*..
gi 221040010 511 VAQIRMAFRYETLCNEL 527
Cdd:cd01319 480 VPQIRMAYRYETLCEEL 496
|
|
| PLN02768 |
PLN02768 |
AMP deaminase |
1-539 |
0e+00 |
|
AMP deaminase
Pssm-ID: 215411 Cd Length: 835 Bit Score: 674.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 1 MQGGILFVYDNKkmleHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSN 80
Cdd:PLN02768 298 MQDGVVHVYANK----DSKEELFPVADATTFFTDLHHILRVIAAGNIRTLCHHRLNLLEQKFNLHLMLNADREFLAQKSA 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 81 PHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTF 160
Cdd:PLN02768 374 PHRDFYNVRKVDTHVHHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGTYLTLKEVFESLDLTGYDLNVDLLDVHADKSTF 453
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 161 HRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVY 240
Cdd:PLN02768 454 HRFDKFNLKYNPCGQSRLREIFLKQDNLIQGRFLAELTKQVFSDLEASKYQMAEYRISIYGRKQSEWDQLASWIVNNELY 533
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 241 SPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK----HSDHMfsd 316
Cdd:PLN02768 534 SENVVWLIQLPRLYNVYKEMGIVTSFQNILDNIFIPLFEVTVDPDSHPQLHVFLKQVVGLDLVDDESKperrPTKHM--- 610
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 317 ksPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQ 396
Cdd:PLN02768 611 --PTPAQWTNVFNPAFSYYVYYCYANLYTLNKLRESKGMTTIKFRPHSGEAGDIDHLAATFLTCHNIAHGINLRKSPVLQ 688
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 397 YLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARN 476
Cdd:PLN02768 689 YLYYLAQIGLAMSPLSNNSLFLDYHRNPFPMFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVWKLSSCDLCEIARN 768
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 221040010 477 SVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELS--FLSDAMKSEEI 539
Cdd:PLN02768 769 SVYQSGFSHALKSHWIGKEYYKRGPDGNDIHKTNVPHIRVEFRDTIWKEEMQqvYLGKAKIPEEV 833
|
|
| PLN03055 |
PLN03055 |
AMP deaminase; Provisional |
1-531 |
0e+00 |
|
AMP deaminase; Provisional
Pssm-ID: 178613 Cd Length: 602 Bit Score: 656.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 1 MQGGILFVYDNKKMLEHqephSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSN 80
Cdd:PLN03055 65 MVDGVMHVYAPDDAKEE----LFPVPDATTFFTDMHRILRIVSLGNVRTFCHHRLKLLEQKFSLHLMLNADREFLAQKSA 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 81 PHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTF 160
Cdd:PLN03055 141 PHRDFYNVRKVDTHVHHSSCMNQKHLLRFIKSKLRKEPDEVVIFRDGKYLTLREVFESLDLTGYDLNVDLLDVHADKNTF 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 161 HRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVY 240
Cdd:PLN03055 221 HRFDKFNLKYNPCGQSRLREIFLKQDNLIQGRFLAELTKEVFSDLEASKYQMAEYRISIYGRKQSEWDQLASWIVNNRLY 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 241 SPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK----HSDHMfsd 316
Cdd:PLN03055 301 SENVVWLIQLPRLYNVYKEMGIVQSFQQILDNIFKPLFEVTVDPSSHPQLHVFLKMVVGFDMVDDESKperrPTKHM--- 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 317 ksPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQ 396
Cdd:PLN03055 378 --QTPEQWDIPFNPAYSYWAYYVYANLYTLNKLRESKGLNTIKFRPHAGEAGDIDHLAAAFLLAHNIAHGNNLRKSPGLQ 455
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 397 YLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARN 476
Cdd:PLN03055 456 YLYYLAQIGLAMSPLSNNSLFLDYHRNPFPMFFARGLNVSLSTDDPLQIHLTKEPLVEEYSIAAQVWKLSSCDLCEIARN 535
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 221040010 477 SVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLS 531
Cdd:PLN03055 536 SVLQSGFPHASKKHWVGDNYWLRGPAGNDIHKTNVPHMRVEFRHEVWKEELQYVF 590
|
|
| PTZ00310 |
PTZ00310 |
AMP deaminase; Provisional |
13-531 |
0e+00 |
|
AMP deaminase; Provisional
Pssm-ID: 240354 [Multi-domain] Cd Length: 1453 Bit Score: 561.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 13 KMLEHQEPHSLPypDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEF--KELKSNPHRDFYNVRK 90
Cdd:PTZ00310 769 KGAVHAWPRFLP--TLTEFIRDLSELRDICSSVEVKRLATKRLENLEHKFRLHLALNHSNEAgtTEERESSNRDFYQAYK 846
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 91 VDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPyDLTVDSLDVHAGRQTFHRFDKFNSKY 170
Cdd:PTZ00310 847 VDTHIHMAAGMTARQLLEFVVDKLLESGDDIAFKRGDHIVTLGQLFSKYGITP-NLTVDQLNVQADHTLFERFDNFNSKY 925
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 171 NPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQV 250
Cdd:PTZ00310 926 NPMENPDLRSLLLKTDNFMKGRYFAELIKDVFEQYSRDRFTYAENRLSIYGINVKEWDDLAHWFDTHGMASKHNKWMIQV 1005
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 251 PRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKhSDHMFSDKSPNPdvWTSEQNP 330
Cdd:PTZ00310 1006 PRVYKVFRAQNVIGSFGQYLDNIFQPLWEASLHPSKHPKFHYFLNHVSGFDSVDNEAT-IDLPFTDVSPWA--WTSVENP 1082
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 331 PYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSP 410
Cdd:PTZ00310 1083 PYNYYLYYLYANIRTLNEFRASRGFSTFALRPHCGESGSMDHLYGAFLCANSICHGINLRNDPPMQYLYYLAQIGLHVSP 1162
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 411 LSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQK 490
Cdd:PTZ00310 1163 LSNNALFLAFLENPFPVFFHRGLNVSLSTDDPLMFHQTQEPLIEEYSIAARVWGLSLNDLCEIARNSVLQSGFDAAFKRN 1242
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 221040010 491 FLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLS 531
Cdd:PTZ00310 1243 AIGDRWYLSSSLGNDSLRTHLSDIRVAFRFETYHTELNFLE 1283
|
|
| PTZ00310 |
PTZ00310 |
AMP deaminase; Provisional |
29-532 |
1.71e-89 |
|
AMP deaminase; Provisional
Pssm-ID: 240354 [Multi-domain] Cd Length: 1453 Bit Score: 300.57 E-value: 1.71e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 29 ETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLN-EMSEfkelKSNPHRD---FYNVRKVDTHIHAAACMNQK 104
Cdd:PTZ00310 146 EQYVRDVQAVYLTVGNGPCLSACRHRLTIIQERSRMFFLLNaEIEE----RADLYKAggvFSPCTKVDNAVLLSTSVDAQ 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 105 HLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFdGLH--MDPYDLTVDSLDVHA--GRQTFHRFDKFNSKyNPVGA--SEL 178
Cdd:PTZ00310 222 ELLEFVVTTYREQPRAPLRLRDGSNSTLREYL-EAHgvRDPRELTVEGLGWQPtkYRNKYGQYDLFDAK-NPMGAlgAEL 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 179 RDLYLKTENYLGGEYFARMVKEvaRELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYS-PNMRWIIQVpriydif 257
Cdd:PTZ00310 300 RQSFLSLHGNLCGKLLRRELER--REYQKQQPQATEYSLPLYGHHPEELTDLAEWVRRQGFGPfSRNRWILAI------- 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 258 RSKKLLPN--------FGKMLENIFLPLFKATINPQDHR--ELHLFLKYVTGFdSVDDESKHSDHMFSDKSPNPDVWTSE 327
Cdd:PTZ00310 371 SFKELGPFqvpsscttVQDQLDNIFLPLFKATLCPSDPQwsDVAWLLCQVGGL-QILTHAVVRSEDFDETAPDPDQVPYT 449
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 328 QNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIA 407
Cdd:PTZ00310 450 AKCSDLYYFYYVYANLAVLNSLRKRKGLNTLQLRPSGEKAPAYDQLISSYLLGDVITRATSIADYPVLQYLCGLHRVGLT 529
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 408 MSPLSNNSL-FLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKETLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQ 486
Cdd:PTZ00310 530 VSPLRDHALsITAYFDHPLPKFLHRCLRVSISTSDPLYFHHHSQPLIEEYATAMKLFSLSPLDTTELARNSVLNSSFPPE 609
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 221040010 487 EKQKFLGQNYYKeGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSD 532
Cdd:PTZ00310 610 VKQQWLGERFQL-GVEGNDFERSGVTNYRLAFREEAWALEEALLND 654
|
|
| ADA_AMPD |
cd00443 |
Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic ... |
89-495 |
5.13e-56 |
|
Adenosine/AMP deaminase. Adenosine deaminases (ADAs) are present in pro- and eukaryotic organisms and catalyze the zinc dependent irreversible deamination of adenosine nucleosides to inosine nucleosides and ammonia. The eukaryotic AMP deaminase catalyzes a similar reaction leading to the hydrolytic removal of an amino group at the 6 position of the adenine nucleotide ring, a branch point in the adenylate catabolic pathway.
Pssm-ID: 238250 Cd Length: 305 Bit Score: 190.25 E-value: 5.13e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 89 RKVDTHIHAAACMNQKHLLRFIKhtyqtepdrtvaekrgrkitlrqvfdglhmdpydltvdsldvhagrqtfhrfdkfns 168
Cdd:cd00443 2 PKVELHAHLSGSISPETLLELIK--------------------------------------------------------- 24
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 169 kynpvgaSELRDLYLKTENYL-GGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEE-WPNLAYWFIQHKVYSPNMRW 246
Cdd:cd00443 25 -------KEFFEKFLLVHNLLqKGEALARALKEVIEEFAEDNVQYLELRTTPRLLETEKgLTKEQYWLLVIEGISEAKQW 97
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 247 --IIQVPRIYDIFRSKkllpnfgkmleniflPLFKATINPQDHRELHLFLK-YVTGFDSVDDESKHsdhmfsdkspnpdv 323
Cdd:cd00443 98 fpPIKVRLILSVDRRG---------------PYVQNYLVASEILELAKFLSnYVVGIDLVGDESKG-------------- 148
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 324 wtseQNPPYSYylyymyanIMVLNNLRRergLSTFLFRPHCGEAGSITHLVSAF-LTADNISHGLLLKKSPVLQYLYYLA 402
Cdd:cd00443 149 ----ENPLRDF--------YSYYEYARR---LGLLGLTLHCGETGNREELLQALlLLPDRIGHGIFLLKHPELIYLVKLR 213
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 403 QIPIAMSPLSNNSLFL--EYSKNPLREFLHKGLHVSLSTDDPMQFHYTketLMEEYAIAAQVWKLSTCDLCEIARNSVLQ 480
Cdd:cd00443 214 NIPIEVCPTSNVVLGTvqSYEKHPFMRFFKAGLPVSLSTDDPGIFGTS---LSEEYSLAAKTFGLTFEDLCELNRNSVLS 290
|
410
....*....|....*
gi 221040010 481 SGLSHQEKQKFLGQN 495
Cdd:cd00443 291 SFAKDEEKKSLLEVL 305
|
|
| Add |
COG1816 |
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the ... |
351-494 |
5.58e-19 |
|
Adenosine deaminase [Nucleotide transport and metabolism]; Adenosine deaminase is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 441421 Cd Length: 326 Bit Score: 87.83 E-value: 5.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 351 RERGLstfLFRPHCGEAGSITHLVSA--FLTADNISHGLLLKKSPVLqyLYYLA--QIPIAMSPLSNNSL--FLEYSKNP 424
Cdd:COG1816 178 REAGL---HLTAHAGEAGGPESIWEAldLLGAERIGHGVRAIEDPAL--VARLAdrGIPLEVCPTSNVQLgvVPSLAEHP 252
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 425 LREFLHKGLHVSLSTDDPMQFHyTkeTLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQ 494
Cdd:COG1816 253 LRRLLDAGVRVTLNTDDPLYFG-T--TLTDEYELAAEAFGLSDADLAQLARNAIEASFLPEEEKAALLAE 319
|
|
| PRK09358 |
PRK09358 |
adenosine deaminase; Provisional |
351-492 |
3.36e-18 |
|
adenosine deaminase; Provisional
Pssm-ID: 236480 Cd Length: 340 Bit Score: 86.00 E-value: 3.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 351 RERGLstfLFRPHCGEAG---SITHLVsAFLTADNISHGLLLKKSPVLqyLYYLA--QIPIAMSPLSNNSL--FLEYSKN 423
Cdd:PRK09358 192 RDAGL---RLTAHAGEAGgpeSIWEAL-DELGAERIGHGVRAIEDPAL--MARLAdrRIPLEVCPTSNVQTgaVPSLAEH 265
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 221040010 424 PLREFLHKGLHVSLSTDDPMQFHyTkeTLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFL 492
Cdd:PRK09358 266 PLKTLLDAGVRVTINTDDPLVFG-T--TLTEEYEALAEAFGLSDEDLAQLARNALEAAFLSEEEKAALL 331
|
|
| ADA |
cd01320 |
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the ... |
351-492 |
5.88e-17 |
|
Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in the purine pathway. Low, as well as high levels of ADA activity have been linked to several diseases.
Pssm-ID: 238645 Cd Length: 325 Bit Score: 81.87 E-value: 5.88e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 351 RERGLStflFRPHCGEAGSITHLVSAF--LTADNISHGLLLKKSPVLqyLYYLA--QIPIAMSPLSNnsLFL----EYSK 422
Cdd:cd01320 183 REAGLR---LTAHAGEAGGPESVRDALdlLGAERIGHGIRAIEDPEL--VKRLAerNIPLEVCPTSN--VQTgavkSLAE 255
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 423 NPLREFLHKGLHVSLSTDDPMQFHytkETLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFL 492
Cdd:cd01320 256 HPLRELLDAGVKVTINTDDPTVFG---TYLTDEYELLAEAFGLTEEELKKLARNAVEASFLSEEEKAELL 322
|
|
| A_deaminase |
pfam00962 |
Adenosine deaminase; |
351-492 |
5.28e-12 |
|
Adenosine deaminase;
Pssm-ID: 425964 Cd Length: 330 Bit Score: 67.07 E-value: 5.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 351 RERGLstfLFRPHCGEAGSITHLVSA--FLTADNISHGLLLKKSPVLqyLYYLA--QIPIAMSPLSN--NSLFLEYSKNP 424
Cdd:pfam00962 185 RDAGL---HLTVHAGEAGGPQSVWEAldDLGAERIGHGVRSAEDPRL--LDRLAdrQIPLEICPTSNvqTGAVASLAEHP 259
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 221040010 425 LREFLHKGLHVSLSTDDPMQFhytKETLMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFL 492
Cdd:pfam00962 260 LKTFLRAGVPVSLNTDDPLMF---GSDLLDEYQVAKRAPGFDEEELARLAKNAVKGSFLPADEKRALL 324
|
|
| metallo-dependent_hydrolases |
cd01292 |
Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a ... |
359-474 |
1.63e-10 |
|
Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The family includes urease alpha, adenosine deaminase, phosphotriesterase dihydroorotases, allantoinases, hydantoinases, AMP-, adenine and cytosine deaminases, imidazolonepropionase, aryldialkylphosphatase, chlorohydrolases, formylmethanofuran dehydrogenases and others.
Pssm-ID: 238617 [Multi-domain] Cd Length: 275 Bit Score: 61.97 E-value: 1.63e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 359 LFRPHCGEAGSITHLVSAFLTAD------NISHGLLLkkSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSK-NPLREFLHK 431
Cdd:cd01292 148 PVVIHAGELPDPTRALEDLVALLrlggrvVIGHVSHL--DPELLELLKEAGVSLEVCPLSNYLLGRDGEGaEALRRLLEL 225
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 221040010 432 GLHVSLSTDDPmqFHYTKETLMEEYAIAAQVWKL--STCDLCEIA 474
Cdd:cd01292 226 GIRVTLGTDGP--PHPLGTDLLALLRLLLKVLRLglSLEEALRLA 268
|
|
| ADGF |
cd01321 |
Adenosine deaminase-related growth factors (ADGF), a novel family of secreted growth-factors ... |
358-492 |
3.67e-07 |
|
Adenosine deaminase-related growth factors (ADGF), a novel family of secreted growth-factors with sequence similarty to adenosine deaminase.
Pssm-ID: 238646 Cd Length: 345 Bit Score: 52.27 E-value: 3.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 358 FLFrpHCGE-AGSIT----HLVSA-FLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSN--NSLFLEYSKNPLREFL 429
Cdd:cd01321 197 FFF--HAGEtNGDGTetdeNLVDAlLLNTKRIGHGFALPKHPLLMDLVKKKNIAIEVCPISNqvLGLVSDLRNHPAAALL 274
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 221040010 430 HKGLHVSLSTDDPMQFHYTK------ETLMeeyAIAAQVWKLSTcdLCEIARNSVLQSGLSHQEKQKFL 492
Cdd:cd01321 275 ARGVPVVISSDDPGFWGAKGlshdfyQAFM---GLAPADAGLRG--LKQLAENSIRYSALSDQEKDEAV 338
|
|
| PTZ00124 |
PTZ00124 |
adenosine deaminase; Provisional |
351-445 |
2.51e-03 |
|
adenosine deaminase; Provisional
Pssm-ID: 173415 Cd Length: 362 Bit Score: 40.23 E-value: 2.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 221040010 351 RERGLSTFLfrpHCGEAGSITHLVSAF-----LTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNnsLFLEYSKN-- 423
Cdd:PTZ00124 216 REAGVNLTV---HAGEDVTLPNLNTLYsaiqvLKVKRIGHGIRVAESQELIDMVKEKDILLEVCPISN--VLLNNAKSmd 290
|
90 100
....*....|....*....|....
gi 221040010 424 --PLREFLHKGLHVSLSTDDPMQF 445
Cdd:PTZ00124 291 thPIRKLYDAGVKVSVNSDDPGMF 314
|
|
| |
