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Conserved domains on  [gi|219524100|ref|YP_002456252|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Deracantha onos]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 6-92 5.91e-22

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 81.74  E-value: 5.91e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  6 NFIMLFLVIFMGLWVFCSNRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYELYFSMVFLTFSVCEGALGLAVLVSMIRTH 85
Cdd:MTH00162  3 MLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRSH 82


                ....*..
gi 219524100 86 GNDFFQT 92
Cdd:MTH00162 83 GNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 6-92 5.91e-22

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 81.74  E-value: 5.91e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  6 NFIMLFLVIFMGLWVFCSNRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYELYFSMVFLTFSVCEGALGLAVLVSMIRTH 85
Cdd:MTH00162  3 MLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRSH 82


                ....*..
gi 219524100 86 GNDFFQT 92
Cdd:MTH00162 83 GNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-98 1.15e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 47.94  E-value: 1.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100   5 VNFIMLFLVIFMGLWVfcsnRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYEL--YFSMVFLTFSVCEGALGLAVLVSMI 82
Cdd:pfam00420  4 LLSGLLFLIGLYGLLL----RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 219524100  83 RTHGNDFFQTFSILQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 6-92 5.91e-22

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 81.74  E-value: 5.91e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  6 NFIMLFLVIFMGLWVFCSNRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYELYFSMVFLTFSVCEGALGLAVLVSMIRTH 85
Cdd:MTH00162  3 MLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRSH 82


                ....*..
gi 219524100 86 GNDFFQT 92
Cdd:MTH00162 83 GNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 7-98 1.84e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 62.68  E-value: 1.84e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  7 FIMLFLVIFMGLWVFCSNRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYELYFSMVFLTFSVCEGALGLAVLVSMIRTHG 86
Cdd:MTH00188  6 ILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHG 85

                        90
                ....*....|..
gi 219524100 87 NDFFQTFSILQC 98
Cdd:MTH00188 86 SDYVSSLNLIKC 97
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 3-98 3.00e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 59.86  E-value: 3.00e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  3 MGVNFIMLFLVIFMGLWVFCSNRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYELYFSMVFLTFSVCEGALGLAVLVSMI 82
Cdd:MTH00149  2 MFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLI 81

                        90
                ....*....|....*.
gi 219524100 83 RTHGNDFFQTFSILQC 98
Cdd:MTH00149 82 RLHGNDYVSSLSSLKF 97
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 1-98 2.40e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 57.31  E-value: 2.40e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  1 MVMGVNFIMLFLVIFMGLWVfcsNRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYELYFS--MVFLTFSVCEGALGLAVL 78
Cdd:MTH00067  2 SPTYFTFYSAFLLGLMGLAF---HRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALM 78

                        90       100
                ....*....|....*....|
gi 219524100 79 VSMIRTHGNDFFQTFSILQC 98
Cdd:MTH00067 79 VATTRTHGTDHLKNLNLLQC 98
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 3-98 2.63e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 57.55  E-value: 2.63e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  3 MGVNFIMLFLVIFMGLWVFCSNRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYELYFSM--VFLTFSVCEGALGLAVLVS 80
Cdd:MTH00125  1 MTPTHFSLYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVA 80

                        90
                ....*....|....*...
gi 219524100 81 MIRTHGNDFFQTFSILQC 98
Cdd:MTH00125 81 TTRTHGSDHLKNLNLLQC 98
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 15-98 5.00e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 56.51  E-value: 5.00e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100 15 FMGLWVFCSNRKHLLSMLLSLE------FIVLGLFSLLYVFLNFyeyeLYFSMVFLTFSVCEGALGLAVLVSMIRTHGND 88
Cdd:MTH00126 13 ILGLMGLAFHRTHLLSALLCLEgmmlslFIALSLWALQLESTSF----SAAPMLLLAFSACEASAGLALLVATARTHGTD 88

                        90
                ....*....|
gi 219524100 89 FFQTFSILQC 98
Cdd:MTH00126 89 RLQNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 5-98 1.03e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 48.00  E-value: 1.03e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  5 VNFIMLFLVIFMGLWVFcsnRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYELYFSM--VFLTFSVCEGALGLAVLVSMI 82
Cdd:MTH00107  6 MNIMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMpiILLVFAACEAAVGLALLVMVS 82

                        90
                ....*....|....*.
gi 219524100 83 RTHGNDFFQTFSILQC 98
Cdd:MTH00107 83 NTYGTDYVQNLNLLQC 98
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 7-96 1.03e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 48.02  E-value: 1.03e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  7 FIMLFLVIFMGLWVFCSNRKHLLSMLLSLEFIVLGLFSLLYVF--LNFYEYELYFSMVFLTFSVCEGALGLAVLVSMIRT 84
Cdd:MTH00181  2 MFVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFslLSSSSSMLMFGLILLTFSACEAVLGLSLLVATNRT 81

                        90
                ....*....|..
gi 219524100 85 HGNDFFQTFSIL 96
Cdd:MTH00181 82 HGSDHLLKFNLL 93
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-98 1.15e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 47.94  E-value: 1.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100   5 VNFIMLFLVIFMGLWVfcsnRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYEL--YFSMVFLTFSVCEGALGLAVLVSMI 82
Cdd:pfam00420  4 LLSGLLFLIGLYGLLL----RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 219524100  83 RTHGNDFFQTFSILQC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-97 1.30e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 45.29  E-value: 1.30e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  3 MGVNFIMLFLVIFMGLWVFCSNRKHLLSMLLSLEFIVLGLFSLLYVFLNFYEYELY--FSMVFLTFSVCEGALGLAVLVS 80
Cdd:MTH00043  1 MNIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVL 80

                        90
                ....*....|....*..
gi 219524100 81 MIRTHGNDFFQTFSILQ 97
Cdd:MTH00043 81 LSRNHNSDLVASLNLLQ 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 9-98 1.54e-07

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 45.13  E-value: 1.54e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 219524100  9 MLFLVIFMGLWVFCSNRKHLLSMLLSLEFIVLGLFSLLYVFLNFY-EYELYFSMVFLTFSVCEGALGLAVLVSMIRTHGN 87
Cdd:MTH00013  7 ILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFAnQVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGN 86

                        90
                ....*....|.
gi 219524100 88 DFFQTFSILQC 98
Cdd:MTH00013 87 DMLKSLTSNKC 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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