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Conserved domains on  [gi|218157328|ref|YP_002364480|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Todiramphus sanctus vagans]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 9.33e-55

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 170.70  E-value: 9.33e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328   1 MIYFMFFLGFCFILGGLAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328  81 AWADWRVLGYGVG-LVMVLVWGVVVSGLVECLKFEVVTVDSGGVGFGRLDFSGVAMFYSWGVGMFLVAGWGLLLTLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 218157328 160 ELVRGLARGAIRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 9.33e-55

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 170.70  E-value: 9.33e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328   1 MIYFMFFLGFCFILGGLAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328  81 AWADWRVLGYGVG-LVMVLVWGVVVSGLVECLKFEVVTVDSGGVGFGRLDFSGVAMFYSWGVGMFLVAGWGLLLTLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 218157328 160 ELVRGLARGAIRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 2.52e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 55.59  E-value: 2.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328   17 LAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSL-AADPFPEAWADWRVLGYGVGLV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 218157328   96 MVLVWGVVVSGLVeclkFEVVTVDSGGVGFGRLDFSGVAMFYSWGVgMFLVAGWGLLLTLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVLLSA----SLTPAAAAAAPDVGNIEAIGELLFTDYLL-PFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 9.33e-55

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 170.70  E-value: 9.33e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328   1 MIYFMFFLGFCFILGGLAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328  81 AWADWRVLGYGVG-LVMVLVWGVVVSGLVECLKFEVVTVDSGGVGFGRLDFSGVAMFYSWGVGMFLVAGWGLLLTLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGfVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 218157328 160 ELVRGLARGAIRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 1.45e-51

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 162.62  E-value: 1.45e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328   1 MIYFMFFLGFCFILGGLAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328  81 AWADWRVLGYGVGLVMVLVWGVVVSGLVECLKFEVVTVDSGGVGFGRLDFSGVAMFYSWGVGMFLVAGWGLLLTLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 218157328 161 LVRGLARGAIRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 1.12e-48

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 155.39  E-value: 1.12e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328   1 MIYFMFFLGFCFILGGLAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328  81 AWADWRVLGYGVGLVMVLVWGVVVSGLVECLKFeVVTVDSGGVGFGRLDFSGVAMFYSWGVGMFLVAGWGLLLTLFVVLE 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEF-LFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                        170
                 ....*....|...
gi 218157328 161 LVRGLARGAIRAV 173
Cdd:MTH00065 160 VTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-164 6.77e-27

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 99.49  E-value: 6.77e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328   1 MIYFMFFLGFCFILGGLAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328  81 AWADwRVLGYGVGLVMVLVWGVVVSGLVECLKFEVVTV----------DSGGVGFGRLDFSGVAMFYSWGVGMFLVAGWG 150
Cdd:MTH00109  82 TWVS-NKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNfnglgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                        170
                 ....*....|....
gi 218157328 151 LLLTLFVVLELVRG 164
Cdd:MTH00109 161 LFIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 6.28e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 94.29  E-value: 6.28e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328   1 MIYFMFFLGFCFILGGLAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSLAADPFPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328  81 AWADWRVLGYGVGLVMVLVWGVVVSGLVECLKFEVvtvdsGGVGFGRLDFSGVAMFYSWGVGMFLVAGWGLLLTLFVVLE 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWM-----GVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 218157328 161 LVRGLARGAIRAV 173
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-172 4.76e-13

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 63.39  E-value: 4.76e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328   1 MIYFMFFLgfCFILGGLAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSLAADPFPe 80
Cdd:MTH00045   1 MVFYLFLI--LMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328  81 awaDWRVLGYGVGLVMVLVWGVVVSglvecLKFEVVTVDSGGVGFGRLDFSGVAMFYSWGVGMFLVAGWGLLLTLFVVLE 160
Cdd:MTH00045  78 ---SVSNLGEVLVLSLLLSLWVFIS-----FDNFLELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALV 149

                        170
                 ....*....|..
gi 218157328 161 LVRGLARGAIRA 172
Cdd:MTH00045 150 ISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 2.52e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 55.59  E-value: 2.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 218157328   17 LAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSL-AADPFPEAWADWRVLGYGVGLV 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 218157328   96 MVLVWGVVVSGLVeclkFEVVTVDSGGVGFGRLDFSGVAMFYSWGVgMFLVAGWGLLLTLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVLLSA----SLTPAAAAAAPDVGNIEAIGELLFTDYLL-PFELASVLLLVALVGAIVL 141
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-73 8.40e-05

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 41.25  E-value: 8.40e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 218157328   7 FLGFCFILGGLAVASNPSPYYGVVGLVLASVVGCGWLLNLGVSFVALVLFMVYLGGMLVVFVYSVSL 73
Cdd:MTH00021   1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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