|
Name |
Accession |
Description |
Interval |
E-value |
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
90-320 |
1.29e-75 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 232.98 E-value: 1.29e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 90 DEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIGEKSFPQIFRQ---- 165
Cdd:cd19493 1 DTALAGGLPLGAITEITGASGSGKTQFALTLASSAAMPARKGGLDGGVLYIDTESKFSAERLAEIAEARFPEAFSGfmee 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 166 EGLAQKMAGRILVLRPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMSSEIEKSATGL--RQHPLRWALSFLKSIAE 243
Cdd:cd19493 81 NERAEEMLKRVAVVRVTTLAQLLERLPNLEEHILSSGVRLVVIDSIAALVRREFGGSDGEVteRHNALAREASSLKRLAE 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 215741600 244 FSQIPVVVTNQVRSQSNDdgyrysfevekkydsnnAEGFESHLVAALGIQWAHAVTIRLVFEAHSGH--RYIKVAKSPM 320
Cdd:cd19493 161 EFRIAVLVTNQATTHFGD-----------------AGDGSSGVTAALGDAWAHAVNTRLRLERCLLQlrRVLEIVKSPL 222
|
|
| XRCC3 |
cd19491 |
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ... |
89-322 |
5.51e-45 |
|
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410899 [Multi-domain] Cd Length: 250 Bit Score: 154.76 E-value: 5.51e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 89 LDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIgEKSFPQIFRQEgL 168
Cdd:cd19491 1 LDELLGGGIPVGGITEIAGESGAGKTQLCLQLALTVQLPRELGGLGGGAVYICTESSFPSKRLQQL-ASSLPKRYHLE-K 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 169 AQKMAGRILVLRPTSLSEFTKSL-EQMKVTLLQHDVKLLVVDSMAALMSSEIEKSATGL--RQHPLRWALSFLKSIAEFS 245
Cdd:cd19491 79 AKNFLDNIFVEHVADLETLEHCLnYQLPALLERGPIRLVVIDSIAALFRSEFDTSRSDLveRAKYLRRLADHLKRLADKY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 246 QIPVVVTNQVRSQ-SNDDGYRYSFEVEKKYDSNNAEGFESHL--VAALGIQWAHAVTIRLVF-----------EAHSGHR 311
Cdd:cd19491 159 NLAVVVVNQVTDRfDSSSDASGLGVLDYLSQFSSFSGGVSGNrkVPALGLTWANLVNTRLMLsrtpkritdssAASISVR 238
|
250
....*....|.
gi 215741600 312 YIKVAKSPMTP 322
Cdd:cd19491 239 RLEVVFSPHLP 249
|
|
| Rad51C |
cd19492 |
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
100-319 |
1.96e-37 |
|
RAD51C recombinase; RAD51C recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51C, together with the other RAD51 paralogs, RAD51B, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site. Additionally, RAD51C acts as a mediator in the early steps of DNA damage signaling.
Pssm-ID: 410900 [Multi-domain] Cd Length: 172 Bit Score: 132.73 E-value: 1.96e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 100 GKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFssrrmieigeksfpqifrqeglaqkmagRILVL 179
Cdd:cd19492 1 GKITEICGVPGVGKTQLCMQLAVNVQIPKCFGGLAGEAIYIDTEGSF----------------------------NIHYF 52
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 180 RPTSLSEFTKSLEQMKVTLLQH-DVKLLVVDSMAALMSSEIEKSatGLRQHPLRWALSFLKSIAEFSQIPVVVTNQVrsq 258
Cdd:cd19492 53 RVHDYVELLALINSLPKFLEDHpKVKLIVVDSIAFPFRHDFDDL--AQRTRLLNGLAQLLHSLARQHNLAVVLTNQV--- 127
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 215741600 259 snddGYRYSfevekkydsnnaEGFESHLVAALGIQWAHAVTIRLVFEAHSGHRYIKVAKSP 319
Cdd:cd19492 128 ----TTKIS------------EDGQSQLVPALGESWSHACTTRLFLTWDEKQRFAHLYKSP 172
|
|
| Rad51 |
pfam08423 |
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ... |
81-346 |
2.50e-33 |
|
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.
Pssm-ID: 462471 [Multi-domain] Cd Length: 255 Bit Score: 124.34 E-value: 2.50e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 81 RLATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIGEKSfp 160
Cdd:pfam08423 18 QITTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLCVTCQLPLEMGGGEGKALYIDTEGTFRPERLVAIAERY-- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 161 qifrqeGLAQKMA-GRILVLRPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMSSEI----EKSAtglRQHPLRWAL 235
Cdd:pfam08423 96 ------GLDPEDVlDNVAYARAYNSEHQMQLLQQAAAMMSESRFALLIVDSATALYRTDFsgrgELAE---RQQHLAKFL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 236 SFLKSIAEFSQIPVVVTNQVrsQSNDDGYRYSFEVEKKydsnnaegfeshlVAALGIQWAHAVTIRLVFEAHSG-HRYIK 314
Cdd:pfam08423 167 RTLQRLADEFGVAVVITNQV--VAQVDGAAGMFSGDPK-------------KPIGGHIMAHASTTRLSLRKGRGeQRICK 231
|
250 260 270
....*....|....*....|....*....|..
gi 215741600 315 VAKSPMTPavafpftvESSGIILLSDEGIDVP 346
Cdd:pfam08423 232 IYDSPCLP--------ESEAVFAIGSGGIIDP 255
|
|
| radA |
PRK04301 |
DNA repair and recombination protein RadA; Validated |
43-336 |
3.63e-29 |
|
DNA repair and recombination protein RadA; Validated
Pssm-ID: 235273 [Multi-domain] Cd Length: 317 Bit Score: 114.59 E-value: 3.63e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 43 DAGIHTARA-AVAHV---SEIACPPYQTALALLEAFRARGD-----------------GRLATTLRGLDEALHGGIPAGK 101
Cdd:PRK04301 24 EAGYDTVEAiAVASPkelSEAAGIGESTAAKIIEAAREAADiggfetalevlerrknvGKITTGSKELDELLGGGIETQS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 102 LTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIeigeksfpQIFRQEGL-AQKMAGRILVLR 180
Cdd:PRK04301 104 ITEFYGEFGSGKTQICHQLAVNVQLPEEKGGLEGKAVYIDTEGTFRPERIE--------QMAEALGLdPDEVLDNIHVAR 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 181 PTSlseftkSLEQM----KVTLL---QHDVKLLVVDSMAALMSSEI---EKSATglRQHPLRWALSFLKSIAEFSQIPVV 250
Cdd:PRK04301 176 AYN------SDHQMllaeKAEELikeGENIKLVIVDSLTAHFRAEYvgrGNLAE--RQQKLNKHLHDLLRLADLYNAAVV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 251 VTNQVrsQSNDDGYrysFEvekkyDSNNAEGfeSHLVaalgiqwAHAVTIRLVF-EAHSGHRYIKVAKSPMTPAVAFPFT 329
Cdd:PRK04301 248 VTNQV--MARPDAF---FG-----DPTQPIG--GHIL-------GHTATFRIYLrKSKGNKRIARLVDSPHLPEGEAVFR 308
|
....*..
gi 215741600 330 VESSGII 336
Cdd:PRK04301 309 ITEEGIR 315
|
|
| archRadA |
cd19515 |
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ... |
82-343 |
2.09e-28 |
|
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)
Pssm-ID: 410923 [Multi-domain] Cd Length: 233 Bit Score: 110.53 E-value: 2.09e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 82 LATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIeigeksfpQ 161
Cdd:cd19515 1 ISTGSKELDKLLGGGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPPEEGGLNGKAVYIDTENTFRPERIM--------Q 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 162 IFRQEGL-AQKMAGRILVLRPTSLSEFTKSLEQMKVTLLQHD-VKLLVVDSMAALMSSE-IEKSATGLRQHPLRWALSFL 238
Cdd:cd19515 73 MAKALGLdPDEVLDNIYVARAYNSNHQMLLVEKAEDLIKEGNnIKLLIVDSLTSHFRAEyVGRGTLAERQQKLNKHLHDL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 239 KSIAEFSQIPVVVTNQVrsQSNDDGYrysfevekkydsnnaegFESHLVAALGIQWAHAVTIRL-VFEAHSGHRYIKVAK 317
Cdd:cd19515 153 HRLADLYNIAVLVTNQV--MAKPDAF-----------------FGDPTQAIGGHILGHAATFRVyLRKGKGGKRIARLVD 213
|
250 260
....*....|....*....|....*.
gi 215741600 318 SPMTPavafpftvESSGIILLSDEGI 343
Cdd:cd19515 214 SPHLP--------EGEAVFRITEKGI 231
|
|
| recomb_radA |
TIGR02236 |
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA ... |
43-335 |
2.75e-28 |
|
DNA repair and recombination protein RadA; This family consists exclusively of archaeal RadA protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239), and archaeal RadB (TIGR02237). This protein is involved in DNA repair and recombination. The member from Pyrococcus horikoshii contains an intein. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 131290 [Multi-domain] Cd Length: 310 Bit Score: 112.14 E-value: 2.75e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 43 DAGIHT----ARAAVAHVSEIACPPYQTALALLEAFRARGD-----------------GRLATTLRGLDEALHGGIPAGK 101
Cdd:TIGR02236 17 EAGYDTfeaiAVASPKELSEIAGISEGTAAKIIQAARKAADlggfetaddvlerrktiGKITTGSKELDELLGGGIETQA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 102 LTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIeigeksfpQIFRQEGL-AQKMAGRILVLR 180
Cdd:TIGR02236 97 ITEVFGEFGSGKTQICHQLAVNVQLPEEKGGLGGKAVYIDTENTFRPERIM--------QMAEARGLdPDEVLKNIYVAR 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 181 PTSLSEFTKSLEQMKVTLLQHD--VKLLVVDSMAALMSSE-IEKSATGLRQHPLRWALSFLKSIAEFSQIPVVVTNQVrs 257
Cdd:TIGR02236 169 AYNSNHQMLLVEKAEDLIKELNnpVKLLIVDSLTSHFRAEyVGRGALAERQQKLNKHLHDLLRLADLYNAAVVVTNQV-- 246
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 215741600 258 QSNDDGYrysfevekkydsnnaegFESHLVAALGIQWAHAVTIRL-VFEAHSGHRYIKVAKSPMTPAVAFPFTVESSGI 335
Cdd:TIGR02236 247 MARPDAF-----------------FGDPTRPIGGHILGHAATFRVyLRKGKGDKRIARLVDSPHLPEGEAVFRITEKGI 308
|
|
| RecA-like |
cd01393 |
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
100-304 |
4.54e-28 |
|
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.
Pssm-ID: 410881 [Multi-domain] Cd Length: 185 Bit Score: 108.21 E-value: 4.54e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 100 GKLTEVVGPSGIGKTQFCLKLALLATLPEcygglnGRVLYIDTESKFSSRRMIEIGEKSfpqiFRQEGLAQKMAGRILVL 179
Cdd:cd01393 1 GKITEIYGPPGSGKTQLALQLAANALLLG------GGVVWIDTEGAFPPSRLVQILEAS----PSSELELAEALSRLLYF 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 180 RPTSLSEFTKSLEQM-KVTLLQHDVKLLVVDSMAALMSSE-----IEKSATGLRQHPLRWALSFLKSIAEFSQIPVVVTN 253
Cdd:cd01393 71 RPPDTLAHLLALDSLpESLFPPPNTSLVVVDSVSALFRKAfprggDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTN 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 215741600 254 QVRSQSnddgyrysfevekkydsnnAEGFE-SHLVAALGIQWAHAVTIRLVF 304
Cdd:cd01393 151 QVTTKI-------------------RGGSGaSLVPPALGNTWEHSVSTRLLL 183
|
|
| radB |
PRK09361 |
DNA repair and recombination protein RadB; Provisional |
78-265 |
2.32e-27 |
|
DNA repair and recombination protein RadB; Provisional
Pssm-ID: 236482 [Multi-domain] Cd Length: 225 Bit Score: 107.64 E-value: 2.32e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 78 GDGRLATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLpecyggLNGRVLYIDTESkFSSRRmieigek 157
Cdd:PRK09361 1 MDERLPTGCKMLDELLGGGFERGTITQIYGPPGSGKTNICLQLAVEAAK------NGKKVIYIDTEG-LSPER------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 158 sFPQIFRQEglAQKMAGRILVLRPTSLSEFTKSLEQMKvTLLQHDVKLLVVDSMAALMSSEIEKSATGL-------RQhp 230
Cdd:PRK09361 67 -FKQIAGED--FEELLSNIIIFEPSSFEEQSEAIRKAE-KLAKENVGLIVLDSATSLYRLELEDEEDNSklnrelgRQ-- 140
|
170 180 190
....*....|....*....|....*....|....*
gi 215741600 231 lrwaLSFLKSIAEFSQIPVVVTNQVRSQSNDDGYR 265
Cdd:PRK09361 141 ----LTHLLKLARKHDLAVVITNQVYSDIDSDGLR 171
|
|
| Rad51_DMC1_archRadA |
cd01123 |
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ... |
82-335 |
2.13e-26 |
|
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .
Pssm-ID: 410868 [Multi-domain] Cd Length: 234 Bit Score: 105.30 E-value: 2.13e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 82 LATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIGEKSfpq 161
Cdd:cd01123 1 ITTGSKELDKLLGGGIETGSITEMFGEFRTGKTQLCHTLAVTCQLPIDRGGGEGKAIYIDTEGTFRPERLRAIAQRF--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 162 ifrqeGLAQKMA-GRILVLRPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMSSE-IEKSATGLRQHPLRWALSFLK 239
Cdd:cd01123 78 -----GLDPDDVlDNVAYARAFNSDHQTQLLDQAAAMMVESRFKLLIVDSATALYRTDySGRGELSARQMHLAKFLRMLQ 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 240 SIAEFSQIPVVVTNQVRSQSndDGYRYSFEVEKKYDSNNAegfeshlvaalgiqWAHAVTIRLVFEAHSG-HRYIKVAKS 318
Cdd:cd01123 153 RLADEFGVAVVVTNQVVAQV--DGAMMFAADPKKPIGGNI--------------LAHASTTRLYLRKGRGeTRICKIYDS 216
|
250
....*....|....*..
gi 215741600 319 PMTPAVAFPFTVESSGI 335
Cdd:cd01123 217 PCLPEAEAVFAITADGV 233
|
|
| Rad51D |
cd19489 |
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
95-310 |
3.98e-26 |
|
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410897 [Multi-domain] Cd Length: 209 Bit Score: 103.87 E-value: 3.98e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 95 GGIPAGKLTEVVGPSGIGKTQFCLKLALLATLpecygGLNGRVLYIDTESKFSSRRMIEIGEKsfpQIFRQEgLAQKMAG 174
Cdd:cd19489 2 GGLRTGEITELVGESSSGKTQLCLTAAANVAS-----RSGQNVLYIDTKSSFSARRLAQILKS---RAQDAE-EIDKALQ 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 175 RILVLRPTSLSEFTKSLEQMKVTLLQH------DVKLLVVDSMAALMSSeIEKSATGLRQHPLRWALS-FLKSIAEFSQI 247
Cdd:cd19489 73 RIRVVRVFDPYELLDLLEELRNTLSQQqenlysRLKLVIIDSLSALISP-LLGGSKHSEGHALLASLArLLKKLAAEYQI 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 215741600 248 PVVVTNQVRSQSNDDgyrysFEVEKKydsnnaegfeshlvAALGIQWAHAVTIRLVFEAHSGH 310
Cdd:cd19489 152 AVLVTNLTVRGGDGG-----QQGSTK--------------PALGEYWESVPSTRLLLSRDEND 195
|
|
| PLN03187 |
PLN03187 |
meiotic recombination protein DMC1 homolog; Provisional |
43-335 |
1.05e-25 |
|
meiotic recombination protein DMC1 homolog; Provisional
Pssm-ID: 215620 [Multi-domain] Cd Length: 344 Bit Score: 105.63 E-value: 1.05e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 43 DAGIHTARAAVAH----------VSE------------IACPPYQTALALLEafRARGDGRLATTLRGLDEALHGGIPAG 100
Cdd:PLN03187 49 DAGIYTCNGLMMHtkknltgikgLSEakvdkiceaaekLLNQGFITGSDALL--KRKSVVRITTGSQALDELLGGGIETR 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 101 KLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIGEKSfpqifrqeGL-AQKMAGRILVL 179
Cdd:PLN03187 127 CITEAFGEFRSGKTQLAHTLCVTTQLPTEMGGGNGKVAYIDTEGTFRPDRIVPIAERF--------GMdADAVLDNIIYA 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 180 RPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMSSE-IEKSATGLRQHPLRWALSFLKSIAEFSQIPVVVTNQVrsQ 258
Cdd:PLN03187 199 RAYTYEHQYNLLLGLAAKMAEEPFRLLIVDSVIALFRVDfTGRGELAERQQKLAQMLSRLTKIAEEFNVAVYMTNQV--I 276
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 215741600 259 SNDDGYRYSFEVEKkydsnnaegfeshlvAALGIQWAHAVTIRLVFEAHSG-HRYIKVAKSPMTPAVAFPFTVESSGI 335
Cdd:PLN03187 277 ADPGGGMFISDPKK---------------PAGGHVLAHAATIRLMLRKGKGeQRVCKVFDAPNLPEAEAEFQITSGGI 339
|
|
| archRadB |
cd01394 |
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ... |
82-262 |
4.46e-25 |
|
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.
Pssm-ID: 410882 [Multi-domain] Cd Length: 216 Bit Score: 101.24 E-value: 4.46e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 82 LATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLAtlpecyGGLNGRVLYIDTESkFSSRRMIEIGEKSFPQ 161
Cdd:cd01394 1 LSTGSKSLDSLLGGGVERGTITQIYGPPGSGKTNICLQLAVEA------AKQGKKVVYIDTEG-LSPERFQQIAGERFES 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 162 IfrqeglaqkmAGRILVLRPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMSSEIEKSATGLRQhpLRWALSFLKSI 241
Cdd:cd01394 74 I----------ASNIIVFEPYSFDEQGVAIQEAEKLLKSDKVDLVVVDSATALYRLELGDDSEANRE--LSRQMSKLLSI 141
|
170 180
....*....|....*....|.
gi 215741600 242 AEFSQIPVVVTNQVRSQSNDD 262
Cdd:cd01394 142 ARKYDIPVVITNQVYSDIDDD 162
|
|
| PTZ00035 |
PTZ00035 |
Rad51 protein; Provisional |
24-336 |
2.32e-23 |
|
Rad51 protein; Provisional
Pssm-ID: 185407 [Multi-domain] Cd Length: 337 Bit Score: 98.92 E-value: 2.32e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 24 LTTAKDVLSLPEVELMGVldAGIHTARAA--VAHVSEIACPPYQTALALLEAfraRGD-GRLATTLRGLDEALHGGIPAG 100
Cdd:PTZ00035 44 ICTVESVAYATKKDLCNI--KGISEAKVEkiKEAASKLVPMGFISATEYLEA---RKNiIRITTGSTQLDKLLGGGIETG 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 101 KLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIGEKsFpqifrqeGL-AQKMAGRILVL 179
Cdd:PTZ00035 119 SITELFGEFRTGKTQLCHTLCVTCQLPIEQGGGEGKVLYIDTEGTFRPERIVQIAER-F-------GLdPEDVLDNIAYA 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 180 RPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMSSEI----EKSAtglRQHPLRWALSFLKSIAEFSQIPVVVTNQV 255
Cdd:PTZ00035 191 RAYNHEHQMQLLSQAAAKMAEERFALLIVDSATALFRVDYsgrgELAE---RQQHLGKFLRALQKLADEFNVAVVITNQV 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 256 RSQSndDGYRYSFEVEKKydsnNAEGfesHLVaalgiqwAHAVTIRLVFEAHSGH-RYIKVAKSPMTPAVAFPFTVESSG 334
Cdd:PTZ00035 268 MADV--DGASMFVADPKK----PIGG---HII-------AHASTTRLSLRKGRGEqRICKIYDSPNLPESEAVFAISEGG 331
|
..
gi 215741600 335 II 336
Cdd:PTZ00035 332 II 333
|
|
| recomb_DMC1 |
TIGR02238 |
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ... |
82-336 |
1.36e-22 |
|
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.
Pssm-ID: 131292 [Multi-domain] Cd Length: 313 Bit Score: 96.39 E-value: 1.36e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 82 LATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIGEKSfpq 161
Cdd:TIGR02238 78 ITTGSQALDGILGGGIESMSITEVFGEFRCGKTQLSHTLCVTAQLPREMGGGNGKVAYIDTEGTFRPDRIRAIAERF--- 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 162 ifrqeGLAQKMA-GRILVLRPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMssEIEKSATGL---RQHPLRWALSF 237
Cdd:TIGR02238 155 -----GVDPDAVlDNILYARAYTSEHQMELLDYLAAKFSEEPFRLLIVDSIMALF--RVDFSGRGElseRQQKLAQMLSR 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 238 LKSIAEFSQIPVVVTNQVRSqsnDDGYRYSFEvekkydSNNAEGFESHLVaalgiqwAHAVTIRLVFEAHSG-HRYIKVA 316
Cdd:TIGR02238 228 LNKISEEFNVAVFVTNQVQA---DPGATMTFI------ADPKKPIGGHVL-------AHASTTRILLRKGRGeERVAKLY 291
|
250 260
....*....|....*....|
gi 215741600 317 KSPMTPAVAFPFTVESSGII 336
Cdd:TIGR02238 292 DSPDMPEAEASFQITEGGIA 311
|
|
| recomb_RAD51 |
TIGR02239 |
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ... |
82-335 |
3.83e-22 |
|
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).
Pssm-ID: 274048 [Multi-domain] Cd Length: 316 Bit Score: 95.18 E-value: 3.83e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 82 LATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIGEKSfpq 161
Cdd:TIGR02239 78 LTTGSKELDKLLGGGIETGSITEIFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERY--- 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 162 ifrqeGLA-QKMAGRILVLRPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMSSEI----EKSAtglRQHPLRWALS 236
Cdd:TIGR02239 155 -----GLNpEDVLDNVAYARAYNTDHQLQLLQQAAAMMSESRFALLIVDSATALYRTDFsgrgELSA---RQMHLARFLR 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 237 FLKSIAEFSQIPVVVTNQVRSQSndDGYRYSFEVEKKydsnnaEGFESHLVaalgiqwAHAVTIRLVFEAHSG-HRYIKV 315
Cdd:TIGR02239 227 SLQRLADEFGVAVVITNQVVAQV--DGAGSMFAGDPK------KPIGGNIM-------AHASTTRLSLRKGRGeQRICKI 291
|
250 260
....*....|....*....|
gi 215741600 316 AKSPMTPAVAFPFTVESSGI 335
Cdd:TIGR02239 292 YDSPCLPESEAMFAIYEDGI 311
|
|
| DMC1 |
cd19514 |
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ... |
89-336 |
7.80e-22 |
|
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.
Pssm-ID: 410922 [Multi-domain] Cd Length: 236 Bit Score: 92.81 E-value: 7.80e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 89 LDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIGEKsfpqiFRQEGl 168
Cdd:cd19514 8 LDKLLGGGIESMSITEVFGEFRTGKTQLSHTLCVTAQLPGSMGGGGGKVAYIDTEGTFRPDRIRPIAER-----FGVDH- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 169 aQKMAGRILVLRPtslseFTkSLEQMKvtLLQH---------DVKLLVVDSMAALMssEIEKSATGL---RQHPLRWALS 236
Cdd:cd19514 82 -DAVLDNILYARA-----YT-SEHQME--LLDYvaakfheeaVFRLLIIDSIMALF--RVDFSGRGElaeRQQKLAQMLS 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 237 FLKSIAEFSQIPVVVTNQVRSqsnDDGYRYSFEVEKKydsnnaEGFESHLVaalgiqwAHAVTIRLVFEAHSGH-RYIKV 315
Cdd:cd19514 151 RLQKISEEYNVAVFITNQVTA---DPGAAMTFQADPK------KPIGGHIL-------AHASTTRISLRKGRGEeRIAKI 214
|
250 260
....*....|....*....|.
gi 215741600 316 AKSPMTPAVAFPFTVESSGII 336
Cdd:cd19514 215 YDSPDLPENEATFAITAGGIA 235
|
|
| PLN03186 |
PLN03186 |
DNA repair protein RAD51 homolog; Provisional |
82-335 |
1.16e-21 |
|
DNA repair protein RAD51 homolog; Provisional
Pssm-ID: 178728 [Multi-domain] Cd Length: 342 Bit Score: 94.41 E-value: 1.16e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 82 LATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIGEKsfpq 161
Cdd:PLN03186 105 ITTGSRELDKILEGGIETGSITEIYGEFRTGKTQLCHTLCVTCQLPLDQGGGEGKAMYIDTEGTFRPQRLIQIAER---- 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 162 iFRQEGLAqkmagrilVLRPTSLSEFTKSLEQMKVTLL------QHDVKLLVVDSMAALMSSEIE-KSATGLRQHPLRWA 234
Cdd:PLN03186 181 -FGLNGAD--------VLENVAYARAYNTDHQSELLLEaasmmaETRFALMIVDSATALYRTEFSgRGELSARQMHLGKF 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 235 LSFLKSIAEFSQIPVVVTNQVRSQSndDGyrysfevekkydsnNAEGFESHLVAALGIQWAHAVTIRLVFEAHSG-HRYI 313
Cdd:PLN03186 252 LRSLQRLADEFGVAVVITNQVVAQV--DG--------------SAFFAGPQLKPIGGNIMAHASTTRLALRKGRGeNRIC 315
|
250 260
....*....|....*....|..
gi 215741600 314 KVAKSPMTPAVAFPFTVESSGI 335
Cdd:PLN03186 316 KVISSPCLPEAEARFSISSEGV 337
|
|
| Rad51 |
cd19513 |
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ... |
82-335 |
2.06e-21 |
|
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.
Pssm-ID: 410921 [Multi-domain] Cd Length: 235 Bit Score: 91.61 E-value: 2.06e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 82 LATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLNGRVLYIDTESKFSSRRMIEIGEKSfpq 161
Cdd:cd19513 1 ITTGSKELDKLLGGGIETGSITELFGEFRTGKTQLCHTLAVTCQLPIDQGGGEGKALYIDTEGTFRPERLLAIAERY--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 162 ifrqeGL-AQKMAGRILVLRPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMSSEI----EKSAtglRQHPLRWALS 236
Cdd:cd19513 78 -----GLnGEDVLDNVAYARAYNTDHQMQLLIQASAMMAESRYALLIVDSATALYRTDYsgrgELSA---RQMHLAKFLR 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 237 FLKSIAEFSQIPVVVTNQVRSQSndDGyrysfevekkydsnnAEGFESHLVAALG--IQwAHAVTIRLVFEAHSG-HRYI 313
Cdd:cd19513 150 MLQRLADEFGVAVVITNQVVAQV--DG---------------AAMFAGDPKKPIGgnIM-AHASTTRLYLRKGRGeTRIC 211
|
250 260
....*....|....*....|..
gi 215741600 314 KVAKSPMTPAVAFPFTVESSGI 335
Cdd:cd19513 212 KIYDSPCLPEAEAVFAITEDGI 233
|
|
| XRCC2 |
cd19490 |
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ... |
100-304 |
1.03e-19 |
|
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.
Pssm-ID: 410898 [Multi-domain] Cd Length: 226 Bit Score: 86.63 E-value: 1.03e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 100 GKLTEVVGPSGIGKTQFCLKLALLATLPECY-----GGLNGRVLYIDTESKFSSRRMIEIGEKSFPQIFRQ------EGL 168
Cdd:cd19490 1 GDVIEITGPSGSGKTELLYHLAARCILPSSWggvplGGLEAAVVFIDTDGRFDILRLRSILEARIRAAIQAanssddEED 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 169 AQKMA----GRILVLRPTSLSEFTKSLEQMKVTLLQH----DVKLLVVDSMAAL-----MSSEIEKSATGLRQHPLRWAL 235
Cdd:cd19490 81 VEEIAreclQRLHIFRCHSSLQLLATLLSLENYLLSLsanpELGLLLIDSISAFywqdrFSAELARAAPLLQEAALRAIL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 215741600 236 SFLKSIAEFSQIPVVVTNQVRSQSNDDgyrySFEVEKKYDSNNAEGFESHLvAALGIQWAHAVTIRLVF 304
Cdd:cd19490 161 RELRRLRRRFQLVVIATKQALFPGKSA----STDNPAANNAVSKASAPSHR-EYLPRPWQRLVTHRLVL 224
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
81-339 |
6.32e-15 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 73.03 E-value: 6.32e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 81 RLATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLAllatlpecYGGL-NG-RVLYIDTESKFSS--RRMIEIGe 156
Cdd:COG0467 1 RVPTGIPGLDELLGGGLPRGSSTLLSGPPGTGKTTLALQFL--------AEGLrRGeKGLYVSFEESPEQllRRAESLG- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 157 ksFPqifrqegLAQKMAGRILVLRPTSLSEFTKSLEQMKVTLLQ----HDVKLLVVDSMAALMSSEIEKSAtgLRQHpLR 232
Cdd:COG0467 72 --LD-------LEEYIESGLLRIIDLSPEELGLDLEELLARLREaveeFGAKRVVIDSLSGLLLALPDPER--LREF-LH 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 233 WALSFLKSIaefsQIPVVVTNQVRSQSNDDGYrysfevekkydsnnaeGFESHLvaalgiqwAHAVtIRLVFEAHSG--H 310
Cdd:COG0467 140 RLLRYLKKR----GVTTLLTSETGGLEDEATE----------------GGLSYL--------ADGV-ILLRYVELGGelR 190
|
250 260 270
....*....|....*....|....*....|.
gi 215741600 311 RYIKVAKSPMTPA--VAFPFTVESSGIILLS 339
Cdd:COG0467 191 RALSVLKMRGSAHdrTIREFEITDGGIEVGE 221
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
93-267 |
1.05e-10 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 61.84 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 93 LHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPECYGGLN---GRVLYIDTESKFSS--RRMIEIGEKSFPQIFrqeg 167
Cdd:COG3598 6 VPGLLPEGGVTLLAGPPGTGKSFLALQLAAAVAAGGPWLGRRvppGKVLYLAAEDDRGElrRRLKALGADLGLPFA---- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 168 laqKMAGRILVLRPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMSSEiEKSATGLRQhplrwALSFLKSIAEFSQI 247
Cdd:COG3598 82 ---DLDGRLRLLSLAGDLDDTDDLEALERAIEEEGPDLVVIDPLARVFGGD-ENDAEEMRA-----FLNPLDRLAERTGA 152
|
170 180
....*....|....*....|...
gi 215741600 248 PVVV---TNQvRSQSNDDGYRYS 267
Cdd:COG3598 153 AVLLvhhTGK-GGAGKDSGDRAR 174
|
|
| RecA |
COG0468 |
RecA/RadA recombinase [Replication, recombination and repair]; |
88-257 |
1.88e-08 |
|
RecA/RadA recombinase [Replication, recombination and repair];
Pssm-ID: 440236 [Multi-domain] Cd Length: 351 Bit Score: 55.18 E-value: 1.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 88 GLDEAL-HGGIPAGKLTEVVGPSGIGKTQFClklalLATLPEC--YGGLngrVLYIDTESKFSSRRmieigeksfpqifr 164
Cdd:COG0468 50 ALDIALgVGGLPRGRIVEIYGPESSGKTTLA-----LHAIAEAqkAGGI---AAFIDAEHALDPEY-------------- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 165 qeglAQKM---AGRILVLRPTSlSEftKSLEQMKvTLLQHD-VKLLVVDSMAALM-SSEIE----KSATGLRQHPLRWAL 235
Cdd:COG0468 108 ----AKKLgvdIDNLLVSQPDT-GE--QALEIAE-TLVRSGaVDLIVVDSVAALVpKAEIEgemgDSHVGLQARLMSQAL 179
|
170 180
....*....|....*....|..
gi 215741600 236 SFLKSIAEFSQIPVVVTNQVRS 257
Cdd:COG0468 180 RKLTGAISKSNTTVIFINQLRE 201
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
88-214 |
2.74e-08 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 53.81 E-value: 2.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 88 GLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLAllatlpecYGGL--NGRVLYIDTESkfSSRRMIEIGEKSFPQIFrq 165
Cdd:cd01124 7 GLDELLGGGIPKGSVTLLTGGPGTGKTLFGLQFL--------YAGAknGEPGLFFTFEE--SPERLLRNAKSFGWDFD-- 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 215741600 166 eglAQKMAGRILVLRPTSLSEFTKSLEQMKVTLLQ----HDVKLLVVDSMAAL 214
Cdd:cd01124 75 ---EMEDEGKLIIVDAPPTEAGRFSLDELLSRILSiiksFKAKRVVIDSLSGL 124
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
79-223 |
7.45e-08 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 52.00 E-value: 7.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 79 DGRLATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLAL-LAT----LPECYGGLNGRVLYIDTESKFS--SRRM 151
Cdd:pfam13481 12 ADGLAAPPPPRRWLIKGLLPAGGLGLLAGAPGTGKTTLALDLAAaVATgkpwLGGPRVPEQGKVLYVSAEGPADelRRRL 91
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 215741600 152 IEIGEKsFPQIFRQEGLAQKMAGRILVLR--PTSLSEFTKSLEQmkvTLLQ-HDVKLLVVDSMAALMSSEIEKSA 223
Cdd:pfam13481 92 RAAGAD-LDLPARLLFLSLVESLPLFFLDrgGPLLDADVDALEA---ALEEvEDPDLVVIDPLARALGGDENSNS 162
|
|
| RadA_SMS_N |
cd01121 |
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ... |
81-255 |
9.58e-06 |
|
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.
Pssm-ID: 410866 [Multi-domain] Cd Length: 268 Bit Score: 46.37 E-value: 9.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 81 RLATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLatlpecYGGLNGRVLYIDteskfssrrmieiGEKSFP 160
Cdd:cd01121 63 RISTGIGELDRVLGGGLVPGSVVLIGGDPGIGKSTLLLQVAAR------LAQRGGKVLYVS-------------GEESLS 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 161 QI-FRQEGLAQKmAGRILVLRPTslseftkSLEQMKVTLLQHDVKLLVVDSMAALMSSEIEKSATGLRQhpLRWALSFLK 239
Cdd:cd01121 124 QIkLRAERLGLG-SDNLYLLAET-------NLEAILAEIEELKPSLVVIDSIQTVYSPELTSSPGSVSQ--VRECAAELL 193
|
170
....*....|....*.
gi 215741600 240 SIAEFSQIPVVVTNQV 255
Cdd:cd01121 194 RLAKETGIPVFLVGHV 209
|
|
| ATPase |
pfam06745 |
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ... |
88-342 |
1.18e-05 |
|
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.
Pssm-ID: 429095 [Multi-domain] Cd Length: 231 Bit Score: 46.08 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 88 GLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLATLPEcygGLNGrvLYIDTESkfSSRRMIEiGEKSF-------- 159
Cdd:pfam06745 7 GLDEILKGGFPEGRVVLITGGPGTGKTIFGLQFLYNGALKY---GEPG--VFVTLEE--PPEDLRE-NARSFgwdlekle 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 160 --PQIFRQEGLAQkMAGRILVLRPTSLSEFTKSLEQmkvtlLQHD--VKLLVVDSMAALmsSEIEKSATGLRQhpLRWAL 235
Cdd:pfam06745 79 eeGKLAIIDASTS-GIGIAEVEDRFDLEELIERLRE-----AIREigAKRVVIDSITTL--FYLLKPAVAREI--LRRLK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 236 SFLKSIAefsqIPVVVTNQVRSQsnddgyrysfevekkydSNNAEGFESHLVAALGIqwahaVTIRLVFEAHSGHRYIKV 315
Cdd:pfam06745 149 RVLKGLG----VTAIFTSEKPSG-----------------EGGIGGYGVEEFIVDGV-----IRLDLKEIEEERVRTIEI 202
|
250 260
....*....|....*....|....*....
gi 215741600 316 AKSPMTP--AVAFPFTVESSGIILLSDEG 342
Cdd:pfam06745 203 VKMRGTPhsMKRYPFEITDNGIVVYPPLE 231
|
|
| KaiC_arch_3 |
TIGR03880 |
KaiC domain protein, AF_0351 family; This model represents a rather narrowly distributed ... |
88-240 |
3.45e-05 |
|
KaiC domain protein, AF_0351 family; This model represents a rather narrowly distributed archaeal protein family in which members have a single copy of the KaiC domain. This stands in contrast to the circadian clock protein KaiC itself, with two copies of the domain. Members are expected to have weak ATPase activity, by homology to the autokinase/autophosphorylase KaiC itself.
Pssm-ID: 163592 Cd Length: 224 Bit Score: 44.70 E-value: 3.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 88 GLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLallatlpeCYGGL-NG-RVLYIDTESKFSsrRMIEIGEKSFPQIfrQ 165
Cdd:TIGR03880 4 GLDEMLGGGFPEGHVIVVIGEYGTGKTTFSLQF--------LYQGLkNGeKAMYISLEEREE--RILGYAKSKGWDL--E 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 215741600 166 EGLAQKMAgrILVLRPtslSEFTKSLEQMK---VTLLQH-DVKLLVVDSMAALmssEIEKSATGLRQHPLRWALSFLKS 240
Cdd:TIGR03880 72 DYIDKSLY--IVRLDP---SDFKTSLNRIKnelPILIKElGASRVVIDPISLL---ETLFDDDAERRTELFRFYSSLRE 142
|
|
| KaiC-N |
cd19485 |
N-terminal domain of Circadian Clock Protein Kaic; KaiC is a circadian clock protein, most ... |
82-116 |
5.52e-05 |
|
N-terminal domain of Circadian Clock Protein Kaic; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410893 [Multi-domain] Cd Length: 226 Bit Score: 43.90 E-value: 5.52e-05
10 20 30
....*....|....*....|....*....|....*
gi 215741600 82 LATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQF 116
Cdd:cd19485 1 LPTGIEGFDDITHGGLPKGRPTLICGTAGTGKTLF 35
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
100-262 |
9.48e-05 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 41.98 E-value: 9.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 100 GKLTEVVGPSGIGKTQFCLKLALLatlpecYGGLNGRVLYIDTESKFSSRRMIEIGeksfpqifrqeglaqkmagrILVL 179
Cdd:smart00382 2 GEVILIVGPPGSGKTTLARALARE------LGPPGGGVIYIDGEDILEEVLDQLLL--------------------IIVG 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 180 RPTSLSEFTKSLEQMKVTLLQHDVKLLVVDSMAALMSSEIEKSATGLRQhplrwaLSFLKSIAEFSQIPVVVTNQVRSQS 259
Cdd:smart00382 56 GKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEE------LRLLLLLKSEKNLTVILTTNDEKDL 129
|
...
gi 215741600 260 NDD 262
Cdd:smart00382 130 GPA 132
|
|
| Sms |
COG1066 |
DNA repair protein RadA/Sms, contains AAA+ ATPase domain [Replication, recombination and ... |
81-225 |
1.34e-04 |
|
DNA repair protein RadA/Sms, contains AAA+ ATPase domain [Replication, recombination and repair];
Pssm-ID: 440685 [Multi-domain] Cd Length: 453 Bit Score: 43.50 E-value: 1.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 81 RLATTLRGLDEALHGGIPAGKLTEVVGPSGIGK----TQFCLKLAllatlpecygGLNGRVLYIdteSkfssrrmieiGE 156
Cdd:COG1066 70 RISTGIGELDRVLGGGLVPGSVVLIGGEPGIGKstllLQVAARLA----------KKGGKVLYV---S----------GE 126
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 215741600 157 KSFPQIfrqeglaqKM-AGRILVLRPT--SLSEfTkSLEQMKVTLLQHDVKLLVVDSMAALMSSEIEkSATG 225
Cdd:COG1066 127 ESASQI--------KLrAERLGLLSDNlyLLAE-T-DLEAILATIEELKPDLLVIDSIQTMYSEELE-SAPG 187
|
|
| circ_KaiC |
TIGR02655 |
circadian clock protein KaiC; Members of this family are the circadian clock protein KaiC, ... |
81-120 |
1.63e-04 |
|
circadian clock protein KaiC; Members of this family are the circadian clock protein KaiC, part of the kaiABC operon that controls circadian rhythm. It may be universal in Cyanobacteria. Each member has two copies of the KaiC domain (pfam06745), which is also found in other proteins. KaiC performs autophosphorylation and acts as its own transcriptional repressor. [Cellular processes, Other]
Pssm-ID: 131703 [Multi-domain] Cd Length: 484 Bit Score: 43.40 E-value: 1.63e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 215741600 81 RLATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKL 120
Cdd:TIGR02655 2 KIRTMIEGFDDISHGGLPIGRSTLVSGTSGTGKTLFSIQF 41
|
|
| RecA |
cd00983 |
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ... |
88-258 |
2.20e-04 |
|
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.
Pssm-ID: 410863 [Multi-domain] Cd Length: 235 Bit Score: 42.16 E-value: 2.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 88 GLDEAL-HGGIPAGKLTEVVGPSGIGKTqfclKLALLAtLPECYgGLNGRVLYIDTE----SKFSSRRMIEIGEksfpqi 162
Cdd:cd00983 11 SLDIALgIGGLPRGRIIEIYGPESSGKT----TLALHA-IAEAQ-KLGGTAAFIDAEhaldPEYAKKLGVDIDN------ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 215741600 163 frqeglaqkmagrILVLRPTSLSEftkSLEQMKVTLLQHDVKLLVVDSMAALM-SSEIEK----SATGLRQHPLRWALSF 237
Cdd:cd00983 79 -------------LLVSQPDTGEQ---ALEIADTLIRSGAVDLIVVDSVAALVpKAEIEGemgdSHVGLQARLMSQALRK 142
|
170 180
....*....|....*....|.
gi 215741600 238 LKSIAEFSQIPVVVTNQVRSQ 258
Cdd:cd00983 143 LTGSLSKSKTTVIFINQLREK 163
|
|
| FlaH |
COG2874 |
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility]; |
89-144 |
2.45e-04 |
|
Archaellum biogenesis ATPase ArlH/FlaH [Cell motility];
Pssm-ID: 442121 Cd Length: 230 Bit Score: 42.13 E-value: 2.45e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 215741600 89 LDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLallatlpeCYGGLNG--RVLYIDTES 144
Cdd:COG2874 10 LDKRLGGGIPLGSLVLIEGENGTGKSVLSQQF--------AYGALENglSVTYISTEL 59
|
|
| PRK09302 |
PRK09302 |
circadian clock protein KaiC; Reviewed |
81-116 |
3.64e-04 |
|
circadian clock protein KaiC; Reviewed
Pssm-ID: 236461 [Multi-domain] Cd Length: 509 Bit Score: 42.17 E-value: 3.64e-04
10 20 30
....*....|....*....|....*....|....*.
gi 215741600 81 RLATTLRGLDEALHGGIPAGKLTEVVGPSGIGKTQF 116
Cdd:PRK09302 12 KLPTGIEGFDDITHGGLPKGRPTLVSGTAGTGKTLF 47
|
|
| PRK06067 |
PRK06067 |
flagellar accessory protein FlaH; Validated |
89-144 |
4.01e-04 |
|
flagellar accessory protein FlaH; Validated
Pssm-ID: 180381 Cd Length: 234 Bit Score: 41.50 E-value: 4.01e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 215741600 89 LDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLallatlpeCYGGLNG--RVLYIDTES 144
Cdd:PRK06067 14 LDRKLGGGIPFPSLILIEGDHGTGKSVLSQQF--------VYGALKQgkKVYVITTEN 63
|
|
| KaiC-like_C |
cd19487 |
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ... |
86-124 |
6.28e-04 |
|
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410895 [Multi-domain] Cd Length: 219 Bit Score: 40.75 E-value: 6.28e-04
10 20 30
....*....|....*....|....*....|....*....
gi 215741600 86 LRGLDEALHGGIPAGKLTEVVGPSGIGKTQFCLKLALLA 124
Cdd:cd19487 5 VPELDELLGGGLERGTSTLLIGPAGVGKSTLALQFAKAA 43
|
|
| |
