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Conserved domains on  [gi|21311935|ref|NP_080838|]
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cyclin N-terminal domain-containing protein 1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CYCLIN_CNTD1 cd20541
cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; ...
 52-179 1.44e-50

cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; CNTD1 is a cyclin-related protein critical for meiotic crossover maturation and deselection of excess precrossover sites. CNTD1 contains one cyclin box. The cyclin box is a protein binding domain.


:

Pssm-ID: 410244  Cd Length: 127  Bit Score: 164.30  E-value: 1.44e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311935  52 FRETRIVEFVFLLSEQWCLEKSVSYQAVEILERFMLKQAEDICRQATLQLRGKDTElQSWRAMKEQLVNKFILRLVSCVQ 131
Cdd:cd20541   1 FKTGRLVEFVFLLCEKLGLPPEVKYLAVELFDRFMSRHIEELYKSVRESNKIKGKK-EEWKEVESRLSKQLPLRLVSCVQ 79

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 21311935 132 LASKLSFHYKIVSNITVLNFLQALGYVHTKEELLESELDILKSLNFQI 179
Cdd:cd20541  80 LASKLSSHYKIVSANKAKNFLQSLGHPYTKSSILKSELRVLKTLNFRV 127
 
Name Accession Description Interval E-value
CYCLIN_CNTD1 cd20541
cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; ...
 52-179 1.44e-50

cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; CNTD1 is a cyclin-related protein critical for meiotic crossover maturation and deselection of excess precrossover sites. CNTD1 contains one cyclin box. The cyclin box is a protein binding domain.


Pssm-ID: 410244  Cd Length: 127  Bit Score: 164.30  E-value: 1.44e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311935  52 FRETRIVEFVFLLSEQWCLEKSVSYQAVEILERFMLKQAEDICRQATLQLRGKDTElQSWRAMKEQLVNKFILRLVSCVQ 131
Cdd:cd20541   1 FKTGRLVEFVFLLCEKLGLPPEVKYLAVELFDRFMSRHIEELYKSVRESNKIKGKK-EEWKEVESRLSKQLPLRLVSCVQ 79

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 21311935 132 LASKLSFHYKIVSNITVLNFLQALGYVHTKEELLESELDILKSLNFQI 179
Cdd:cd20541  80 LASKLSSHYKIVSANKAKNFLQSLGHPYTKSSILKSELRVLKTLNFRV 127
Cyclin_N pfam00134
Cyclin, N-terminal domain; Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a ...
 57-180 1.44e-03

Cyclin, N-terminal domain; Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a Uracil-DNA glycosylase that is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the N-terminal domain.


Pssm-ID: 459686 [Multi-domain]  Cd Length: 127  Bit Score: 38.27  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311935    57 IVEFVFLLSEQWCLEKSVSYQAVEILERFMLKQaedICRQATLQLRGkdtelqswramkeqlvnkfilrlVSCVQLASKl 136
Cdd:pfam00134  34 LIDWLVEVHEKFKLLPETLYLAVNYLDRFLSKK---SVPKNKLQLVG-----------------------VTCLFIAAK- 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 21311935   137 sfhYKIVSNITVLNFLQALGYVHTKEELLESELDILKSLNFQIN 180
Cdd:pfam00134  87 ---YEEIYPPTVEDLVYITDNAYTREEILRMERLILETLNFDLS 127
 
Name Accession Description Interval E-value
CYCLIN_CNTD1 cd20541
cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; ...
 52-179 1.44e-50

cyclin box found in Cyclin N-terminal domain-containing protein 1 (CNTD1) and similar proteins; CNTD1 is a cyclin-related protein critical for meiotic crossover maturation and deselection of excess precrossover sites. CNTD1 contains one cyclin box. The cyclin box is a protein binding domain.


Pssm-ID: 410244  Cd Length: 127  Bit Score: 164.30  E-value: 1.44e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311935  52 FRETRIVEFVFLLSEQWCLEKSVSYQAVEILERFMLKQAEDICRQATLQLRGKDTElQSWRAMKEQLVNKFILRLVSCVQ 131
Cdd:cd20541   1 FKTGRLVEFVFLLCEKLGLPPEVKYLAVELFDRFMSRHIEELYKSVRESNKIKGKK-EEWKEVESRLSKQLPLRLVSCVQ 79

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 21311935 132 LASKLSFHYKIVSNITVLNFLQALGYVHTKEELLESELDILKSLNFQI 179
Cdd:cd20541  80 LASKLSSHYKIVSANKAKNFLQSLGHPYTKSSILKSELRVLKTLNFRV 127
Cyclin_N pfam00134
Cyclin, N-terminal domain; Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a ...
 57-180 1.44e-03

Cyclin, N-terminal domain; Cyclins regulate cyclin dependent kinases (CDKs). Swiss:P22674 is a Uracil-DNA glycosylase that is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the N-terminal domain.


Pssm-ID: 459686 [Multi-domain]  Cd Length: 127  Bit Score: 38.27  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311935    57 IVEFVFLLSEQWCLEKSVSYQAVEILERFMLKQaedICRQATLQLRGkdtelqswramkeqlvnkfilrlVSCVQLASKl 136
Cdd:pfam00134  34 LIDWLVEVHEKFKLLPETLYLAVNYLDRFLSKK---SVPKNKLQLVG-----------------------VTCLFIAAK- 86

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 21311935   137 sfhYKIVSNITVLNFLQALGYVHTKEELLESELDILKSLNFQIN 180
Cdd:pfam00134  87 ---YEEIYPPTVEDLVYITDNAYTREEILRMERLILETLNFDLS 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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