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Conserved domains on  [gi|21311520|gb|AAM46762|]
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flavin-containing monooxygenase 2 [Rattus norvegicus]

Protein Classification

flavin-binding monooxygenase-like family protein( domain architecture ID 1000557)

flavin-binding monooxygenase-like family protein; such as flavin-containing monooxygenases (FMOs) that catalyze the monooxygenation of a variety of substrates

EC:  1.14.13.-
Gene Ontology:  GO:0004497

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FMO-like super family cl30939
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 3-421 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


The actual alignment was detected with superfamily member pfam00743:

Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 856.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520     3 KKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVEDGRASIYHSVITNTSKEMSCFSDFPMPEDFPNFL 82
Cdd:pfam00743   2 KKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNFM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520    83 HNSKLLEYFRIFAKKFDLLKYIQFQTTVISVKKRPDFASSGQWDVYVQSNGKEQRAVFDAVMVCSGHHIQPHLPLKSFPG 162
Cdd:pfam00743  82 HNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFPG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   163 IERFQGQYFHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVSTRHGSWVMSRISEDGYPWDMVFHTRFSSM 242
Cdd:pfam00743 162 IEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTSF 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   243 LRNVLPRTVVKWMMERQMNRWFNHENYGLVPQNKYLMKEPVLNDDLPSRLLYGAIKVKTRVKELTETAVVFEDGTVEEDV 322
Cdd:pfam00743 242 LRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEEDI 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   323 DVIVFATGYTFSFPFLEDSLVKVEDNKVSLYKAMFPPHLEKPTLACIGLIQPLGSIFPTVELQARWATRVFKGVCRLPSE 402
Cdd:pfam00743 322 DVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPSQ 401

                         410
                  ....*....|....*....
gi 21311520   403 TTMMADIAERNEKRIDLFG 421
Cdd:pfam00743 402 SEMMAEINKRQEKKIKRFG 420
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 3-421 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 856.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520     3 KKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVEDGRASIYHSVITNTSKEMSCFSDFPMPEDFPNFL 82
Cdd:pfam00743   2 KKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNFM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520    83 HNSKLLEYFRIFAKKFDLLKYIQFQTTVISVKKRPDFASSGQWDVYVQSNGKEQRAVFDAVMVCSGHHIQPHLPLKSFPG 162
Cdd:pfam00743  82 HNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFPG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   163 IERFQGQYFHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVSTRHGSWVMSRISEDGYPWDMVFHTRFSSM 242
Cdd:pfam00743 162 IEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTSF 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   243 LRNVLPRTVVKWMMERQMNRWFNHENYGLVPQNKYLMKEPVLNDDLPSRLLYGAIKVKTRVKELTETAVVFEDGTVEEDV 322
Cdd:pfam00743 242 LRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEEDI 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   323 DVIVFATGYTFSFPFLEDSLVKVEDNKVSLYKAMFPPHLEKPTLACIGLIQPLGSIFPTVELQARWATRVFKGVCRLPSE 402
Cdd:pfam00743 322 DVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPSQ 401

                         410
                  ....*....|....*....
gi 21311520   403 TTMMADIAERNEKRIDLFG 421
Cdd:pfam00743 402 SEMMAEINKRQEKKIKRFG 420
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 5-394 2.83e-94

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 289.84  E-value: 2.83e-94
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   5 VAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRfkenveDGRasiYHSVITNTSKEMSCFSDFPMPEDFPNFLHN 84
Cdd:COG2072   9 VVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWR------DNR---YPGLRLDTPSHLYSLPFFPNWSDDPDFPTG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  85 SKLLEYFRIFAKKFDLLKYIQFQTTVISVKKRPDfasSGQWDVYVqSNGKEQRAvfDAVMVCSGHHIQPHLPlkSFPGIE 164
Cdd:COG2072  80 DEILAYLEAYADKFGLRRPIRFGTEVTSARWDEA---DGRWTVTT-DDGETLTA--RFVVVATGPLSRPKIP--DIPGLE 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520 165 RFQGQYFHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVSTRHGSWVMSRisEDGYPWDMVFHTRFSSMLR 244
Cdd:COG2072 152 DFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPR--PNYDPERGRPANYLGLEAP 229

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520 245 NVLPRTVVKWMMERQMNRWFNHENYG-LVPQNKYLMKEPVLNDDLPSRLLYGAIKVKT-RVKELTETAVVFEDGTvEEDV 322
Cdd:COG2072 230 PALNRRDARAWLRRLLRAQVKDPELGlLTPDYPPGCKRPLLSTDYYEALRRGNVELVTgGIERITEDGVVFADGT-EHEV 308

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 21311520 323 DVIVFATGYTFSFPFLEDSLVKVEDNKVS--LYKAMFPPHLekPTLACIGLIQPLG--SIFPTVELQARWATRVFK 394
Cdd:COG2072 309 DVIVWATGFRADLPWLAPLDVRGRDGRSGprAYLGVVVPGF--PNLFFLGPNSPSGhsSLTLGAERQARYIARLIA 382
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 3-424 8.30e-48

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 170.04  E-value: 8.30e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520    3 KKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVEDG-----------RASIYHSVITNTSKEMSCFSD 71
Cdd:PLN02172  11 QHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTPKSESDplsldptrsivHSSVYESLRTNLPRECMGYRD 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   72 FPM----------PEDFPNflhNSKLLEYFRIFAKKFDLLKYIQFQTTVISVKkrpdfASSGQWDVYVQ-SNGKEQRAVF 140
Cdd:PLN02172  91 FPFvprfddesrdSRRYPS---HREVLAYLQDFAREFKIEEMVRFETEVVRVE-----PVDGKWRVQSKnSGGFSKDEIF 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  141 DAVMVCSGHHIQPHLplKSFPGIERFQGQYFHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVStrhgswv 220
Cdd:PLN02172 163 DAVVVCNGHYTEPNV--AHIPGIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIA------- 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  221 mSRISEdgypwdmvFHTrfssmlRNVLPrtvvkwmmerqmnrwfnhenyglVPQNKYLMKEPV--LNDDlpsrllyGAIk 298
Cdd:PLN02172 234 -SRASE--------SDT------YEKLP-----------------------VPQNNLWMHSEIdtAHED-------GSI- 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  299 vktrvkeltetavVFEDGTVEEdVDVIVFATGYTFSFPFLE-DSLVKVEDNKVS-LYKAMFPPHLeKPTLACIGLiQPLG 376
Cdd:PLN02172 268 -------------VFKNGKVVY-ADTIVHCTGYKYHFPFLEtNGYMRIDENRVEpLYKHVFPPAL-APGLSFIGL-PAMG 331

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*...
gi 21311520  377 SIFPTVELQARWATRVFKGVCRLPSETTMMADIAERNEKRiDLFGKPE 424
Cdd:PLN02172 332 IQFVMFEIQSKWVAAVLSGRVTLPSEDKMMEDINAWYASL-EALGIPK 378
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 3-421 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 856.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520     3 KKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVEDGRASIYHSVITNTSKEMSCFSDFPMPEDFPNFL 82
Cdd:pfam00743   2 KKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNFM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520    83 HNSKLLEYFRIFAKKFDLLKYIQFQTTVISVKKRPDFASSGQWDVYVQSNGKEQRAVFDAVMVCSGHHIQPHLPLKSFPG 162
Cdd:pfam00743  82 HNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFPG 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   163 IERFQGQYFHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVSTRHGSWVMSRISEDGYPWDMVFHTRFSSM 242
Cdd:pfam00743 162 IEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTSF 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   243 LRNVLPRTVVKWMMERQMNRWFNHENYGLVPQNKYLMKEPVLNDDLPSRLLYGAIKVKTRVKELTETAVVFEDGTVEEDV 322
Cdd:pfam00743 242 LRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKEPVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEEDI 321

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   323 DVIVFATGYTFSFPFLEDSLVKVEDNKVSLYKAMFPPHLEKPTLACIGLIQPLGSIFPTVELQARWATRVFKGVCRLPSE 402
Cdd:pfam00743 322 DVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPSQ 401

                         410
                  ....*....|....*....
gi 21311520   403 TTMMADIAERNEKRIDLFG 421
Cdd:pfam00743 402 SEMMAEINKRQEKKIKRFG 420
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 5-394 2.83e-94

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 289.84  E-value: 2.83e-94
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   5 VAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRfkenveDGRasiYHSVITNTSKEMSCFSDFPMPEDFPNFLHN 84
Cdd:COG2072   9 VVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWR------DNR---YPGLRLDTPSHLYSLPFFPNWSDDPDFPTG 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  85 SKLLEYFRIFAKKFDLLKYIQFQTTVISVKKRPDfasSGQWDVYVqSNGKEQRAvfDAVMVCSGHHIQPHLPlkSFPGIE 164
Cdd:COG2072  80 DEILAYLEAYADKFGLRRPIRFGTEVTSARWDEA---DGRWTVTT-DDGETLTA--RFVVVATGPLSRPKIP--DIPGLE 151

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520 165 RFQGQYFHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVSTRHGSWVMSRisEDGYPWDMVFHTRFSSMLR 244
Cdd:COG2072 152 DFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPR--PNYDPERGRPANYLGLEAP 229

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520 245 NVLPRTVVKWMMERQMNRWFNHENYG-LVPQNKYLMKEPVLNDDLPSRLLYGAIKVKT-RVKELTETAVVFEDGTvEEDV 322
Cdd:COG2072 230 PALNRRDARAWLRRLLRAQVKDPELGlLTPDYPPGCKRPLLSTDYYEALRRGNVELVTgGIERITEDGVVFADGT-EHEV 308

                       330       340       350       360       370       380       390
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 21311520 323 DVIVFATGYTFSFPFLEDSLVKVEDNKVS--LYKAMFPPHLekPTLACIGLIQPLG--SIFPTVELQARWATRVFK 394
Cdd:COG2072 309 DVIVWATGFRADLPWLAPLDVRGRDGRSGprAYLGVVVPGF--PNLFFLGPNSPSGhsSLTLGAERQARYIARLIA 382
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 3-424 8.30e-48

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 170.04  E-value: 8.30e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520    3 KKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRFKENVEDG-----------RASIYHSVITNTSKEMSCFSD 71
Cdd:PLN02172  11 QHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTPKSESDplsldptrsivHSSVYESLRTNLPRECMGYRD 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   72 FPM----------PEDFPNflhNSKLLEYFRIFAKKFDLLKYIQFQTTVISVKkrpdfASSGQWDVYVQ-SNGKEQRAVF 140
Cdd:PLN02172  91 FPFvprfddesrdSRRYPS---HREVLAYLQDFAREFKIEEMVRFETEVVRVE-----PVDGKWRVQSKnSGGFSKDEIF 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  141 DAVMVCSGHHIQPHLplKSFPGIERFQGQYFHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVStrhgswv 220
Cdd:PLN02172 163 DAVVVCNGHYTEPNV--AHIPGIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIA------- 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  221 mSRISEdgypwdmvFHTrfssmlRNVLPrtvvkwmmerqmnrwfnhenyglVPQNKYLMKEPV--LNDDlpsrllyGAIk 298
Cdd:PLN02172 234 -SRASE--------SDT------YEKLP-----------------------VPQNNLWMHSEIdtAHED-------GSI- 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  299 vktrvkeltetavVFEDGTVEEdVDVIVFATGYTFSFPFLE-DSLVKVEDNKVS-LYKAMFPPHLeKPTLACIGLiQPLG 376
Cdd:PLN02172 268 -------------VFKNGKVVY-ADTIVHCTGYKYHFPFLEtNGYMRIDENRVEpLYKHVFPPAL-APGLSFIGL-PAMG 331

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*...
gi 21311520  377 SIFPTVELQARWATRVFKGVCRLPSETTMMADIAERNEKRiDLFGKPE 424
Cdd:PLN02172 332 IQFVMFEIQSKWVAAVLSGRVTLPSEDKMMEDINAWYASL-EALGIPK 378
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
88-353 3.09e-18

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 84.58  E-value: 3.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520    88 LEYFRIFAKKFDLLkyIQFQTTVISVKKRPDFASsgqwdvyVQSNGKEQRAVFdaVMVCSGHHIQPHLPLKSFPGIerfq 167
Cdd:pfam13738  78 AEYLRRVADHFELP--INLFEEVTSVKKEDDGFV-------VTTSKGTYQARY--VIIATGEFDFPNKLGVPELPK---- 142

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   168 gqyfHSRQYKHPVGYEGKRILVVGIGNSAADIASELSKRAAQVFVSTRHGSWvmsrisedgypwdMVFHTRFSSMLRnvl 247
Cdd:pfam13738 143 ----HYSYVKDFHPYAGQKVVVIGGYNSAVDAALELVRKGARVTVLYRGSEW-------------EDRDSDPSYSLS--- 202

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   248 PRTVvkwmmerqmNRwfnhenyglvpqnkylMKEPVLNddlpsrllyGAIKV--KTRVKELTETAVV----FEDGTVEED 321
Cdd:pfam13738 203 PDTL---------NR----------------LEELVKN---------GKIKAhfNAEVKEITEVDVSykvhTEDGRKVTS 248

                         250       260       270
                  ....*....|....*....|....*....|..
gi 21311520   322 VDVIVFATGYTFSFPFLEDSLVKVEDNKVSLY 353
Cdd:pfam13738 249 NDDPILATGYHPDLSFLKKGLFELDEDGRPVL 280
IucD COG3486
Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport and catabolism] ...
 78-340 8.01e-09

Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442709 [Multi-domain]  Cd Length: 440  Bit Score: 57.49  E-value: 8.01e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  78 FPNFLHNSKLLEYFrIFAKKFDLLK-----YIQ----------FQTTVISVkkRPDfASSGQWDVYVQsNGKEQRAVFDA 142
Cdd:COG3486  75 FLNYLKEHGRLYDF-YNRENFFPLRreyndYCRwaaeqldnvrFGTEVEAV--EYD-DDAGAFRVTVR-DGTGERETYRA 149

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520 143 vmvcsgHHI------QPHLP--LKSFPGierfqGQYFHSRQYKH--PVGYEGKRILVVGIGNSAADIA----SELSKRAA 208
Cdd:COG3486 150 ------RNLvlgtgtRPYLPecFRGLPG-----ERVFHSSEYLHrkEDLQAAKRVTVVGSGQSAAEIFldllRRQDGPGA 218

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520 209 QVfvstrhgSWVMSRiseDGY--------------PwDMV--FHTrfssmlrnvLPRTVvkwmmeRQMnrwfnhenygLV 272
Cdd:COG3486 219 EL-------TWVTRS---PGFfpldyskftneifsP-EYVdyFYA---------LPEEV------RDR----------LL 262

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520 273 PQNKYLMKepVLNDDLPS---RLLY------GAIKVK----TRVKELTETA----VVFE----DGTVEEDVDVIVFATGY 331
Cdd:COG3486 263 AEQKLLYK--GISPDLINeiyDLLYersvggDPPRVRllpnSEVTAVERAGggyrLTLRhletGERFELETDAVVLATGY 340

                       330
                ....*....|
gi 21311520 332 TFSFP-FLED 340
Cdd:COG3486 341 RPRLPaFLEP 350
Lys_Orn_oxgnase pfam13434
L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold ...
 78-333 1.82e-07

L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold oxidoreductases that catalyze NADPH-dependent hydroxylation and are involved in siderophore biosynthesis. This family includes L-ornithine 5-monooxygenase, which catalyzes the hydroxylation of L-ornithine at the N5 position, and L-lysine 6-monooxygenase, which catalyzes the hydroxylation of lysine at the N6 position (EC:1.14.13.59).


Pssm-ID: 433204 [Multi-domain]  Cd Length: 338  Bit Score: 52.59  E-value: 1.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520    78 FPNFLHNSKLL------EYFRIFAKKFD---------LLKYIQFQTTVISVkkRPDfASSGQWDVYVQSNGKEQRAV-FD 141
Cdd:pfam13434  71 FLNYLHEHGRLysfynlETFFPSRREFNdylqwaashLPNRLRFGQEVESV--EPD-AERGEPLLRVRVRDADGEETtFL 147

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   142 AVMVCSGHHIQPHLPlKSFPGIERFqgqyFHSRQY--KHPVGYEGKRILVVGIGNSAADIASELSKR--AAQVfvstrhg 217
Cdd:pfam13434 148 ARNLVLGTGGEPYIP-ECARGGERV----FHSSEYleRIDRLAAKKRIAVVGSGQSAAEIFRDLLRRgpAYEL------- 215

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   218 SWVMSRI----SEDG-------------YPWDMVFHTRfssmlrnvlprtvvkwmmeRQMNRWFNHENYG-----LVPQN 275
Cdd:pfam13434 216 TWVTRSPnffpLDDSpfvneifspeyvdYFYSLPEDTR-------------------RALLREQKGTNYDgidpsLIEEI 276

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 21311520   276 KYLMKEPVLNDDLPSRLLYGaikvkTRVKELTETA-----VVFEDG----TVEEDVDVIVFATGYTF 333
Cdd:pfam13434 277 YRLLYEQRVDGDPRHRLLPN-----REVQSAERVGdggveLTLRDGeqgrEETLETDVVVLATGYRR 338
YdhS COG4529
Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];
3-217 4.61e-07

Uncharacterized NAD(P)/FAD-binding protein YdhS [General function prediction only];


Pssm-ID: 443597 [Multi-domain]  Cd Length: 466  Bit Score: 51.88  E-value: 4.61e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   3 KKVAVIGAGVSG---LISLKCCVDEGLEPTCFERTEDIGGlwrfkenvedGRAsiYH----SVITNT-SKEMSCFSDfpM 74
Cdd:COG4529   6 KRIAIIGGGASGtalAIHLLRRAPEPLRITLFEPRPELGR----------GVA--YStdspEHLLNVpAGRMSAFPD--D 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  75 PEDFPNFLHNSKLLEYFRIFAKKF-----------DLLKYIQ-----------FQTTVISVKKRpdfasSGQWDVYVQSN 132
Cdd:COG4529  72 PDHFLRWLRENGARAAPAIDPDAFvprrlfgeylrERLAEALarapagvrlrhIRAEVVDLERD-----DGGYRVTLADG 146

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520 133 gkeQRAVFDAVMVCSGHHiQPHLPlksfPGIERFQGQYFHSrqykhPvgYE---------GKRILVVGIGNSAADIASEL 203
Cdd:COG4529 147 ---ETLRADAVVLATGHP-PPAPP----PGLAAGSPRYIAD-----P--WPpgalarippDARVLIIGTGLTAIDVVLSL 211

                       250
                ....*....|....*.
gi 21311520 204 SKR--AAQVFVSTRHG 217
Cdd:COG4529 212 AARghRGPITALSRRG 227
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
4-215 6.40e-07

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 50.89  E-value: 6.40e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520   4 KVAVIGAGVSGL---ISLKccvDEGLEPTCFERTEdIGG-LWRFKEnvedgrasIYhsvitntskemscfsDFPmpeDFP 79
Cdd:COG0492   2 DVVIIGAGPAGLtaaIYAA---RAGLKTLVIEGGE-PGGqLATTKE--------IE---------------NYP---GFP 51

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520  80 NFLHNSKLLEYFRIFAKKFDllkyIQFQTT-VISVKKrpdfaSSGQWDVYVqSNGKEQRAvfDAVMVCSGhhIQP-HLPL 157
Cdd:COG0492  52 EGISGPELAERLREQAERFG----AEILLEeVTSVDK-----DDGPFRVTT-DDGTEYEA--KAVIIATG--AGPrKLGL 117

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 21311520 158 ksfPGIERFQGQ----------YFhsrqykhpvgYEGKRILVVGIGNSAADIASELSKRAAQVFVSTR 215
Cdd:COG0492 118 ---PGEEEFEGRgvsycatcdgFF----------FRGKDVVVVGGGDSALEEALYLTKFASKVTLIHR 172
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
7-57 2.89e-04

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 39.05  E-value: 2.89e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 21311520     7 VIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGL---WRFKENVEDGRASIYHS 57
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRLGGNaysYRVPGYVFDYGAHIFHG 54
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 3-43 3.10e-04

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 42.84  E-value: 3.10e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 21311520    3 KKVAVIGAGVSGLislkCCVDE----GLEPTCFERTEDIGGLWRF 43
Cdd:PRK12810 144 KKVAVVGSGPAGL----AAADQlaraGHKVTVFERADRIGGLLRY 184
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 3-43 2.39e-03

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 40.12  E-value: 2.39e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 21311520    3 KKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGLWRF 43
Cdd:PRK12769 328 KRVAIIGAGPAGLACADVLARNGVAVTVYDRHPEIGGLLTF 368
PRK07233 PRK07233
hypothetical protein; Provisional
 4-40 3.22e-03

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 39.48  E-value: 3.22e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 21311520    4 KVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGL 40
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGL 37
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 3-43 3.36e-03

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 39.73  E-value: 3.36e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 21311520   3 KKVAVIGAGVSGLislkCC----VDEGLEPTCFERTEDIGGLWRF 43
Cdd:COG0493 122 KKVAVVGSGPAGL----AAayqlARAGHEVTVFEALDKPGGLLRY 162
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-40 4.05e-03

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 39.43  E-value: 4.05e-03
                        10        20        30
                ....*....|....*....|....*....|....*...
gi 21311520   3 KKVAVIGAGVSGLISLKCCVDEGLEPTCFERTEDIGGL 40
Cdd:COG1232   2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGL 39
NAD_binding_9 pfam13454
FAD-NAD(P)-binding;
6-149 5.27e-03

FAD-NAD(P)-binding;


Pssm-ID: 433222 [Multi-domain]  Cd Length: 155  Bit Score: 37.26  E-value: 5.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520     6 AVIGAGVSGLIS----LKCCVDEGLEPTCFERTED-IGGLWRfkenvedGRASIYHsvITNT-SKEMSCFSDfpMPEDFP 79
Cdd:pfam13454   1 AIVGGGPSGLALlerlLARAPKRPLEITLFDPSPPgAGGVYR-------TDQSPEH--LLNVpASRMSLFPD--DPPHFL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 21311520    80 NFLHNSKLLEYF-----RIFAKKFDLLKYIQFQ------------------TTVISVKKRPDfassgqwDVYVQSNGKEQ 136
Cdd:pfam13454  70 EWLRARGALDEApgldpDDFPPRALYGRYLRDRfeealarapagvtvrvhrARVTDLRPRGD-------GYRVLLADGRT 142

                         170
                  ....*....|...
gi 21311520   137 RAvFDAVMVCSGH 149
Cdd:pfam13454 143 LA-ADAVVLATGH 154
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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