NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2130626257|gb|UEK75814|]
View 

NADH dehydrogenase subunit 2 (mitochondrion) [Coptotettix longtanensis]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475933)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-332 4.24e-74

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 231.64  E-value: 4.24e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257   1 MKKMPMKIMFYTTLITSTLITITATSWLGVWMGLEINMLSFIPLMSNKSMYMT--SSIKYFITQTLASIALITSFITLTM 78
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSseSSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  79 NLFNQNKeIINIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYIEVNQMFMTtIIIMSAIIGA 158
Cdd:MTH00160   81 NLMLFNN-ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIII-IIILSAIIGA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 159 IMGLNQISLRLILAYSSINHMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAI 238
Cdd:MTH00160  159 IGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFL 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 239 SFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSLKENKWTKNNFTIKNKTS-FML 317
Cdd:MTH00160  239 NLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLIlNFL 318

                         330
                  ....*....|....*
gi 2130626257 318 NSVSTLGMLMSPLFL 332
Cdd:MTH00160  319 SFISLFGLILSSLLF 333
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-332 4.24e-74

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 231.64  E-value: 4.24e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257   1 MKKMPMKIMFYTTLITSTLITITATSWLGVWMGLEINMLSFIPLMSNKSMYMT--SSIKYFITQTLASIALITSFITLTM 78
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSseSSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  79 NLFNQNKeIINIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYIEVNQMFMTtIIIMSAIIGA 158
Cdd:MTH00160   81 NLMLFNN-ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIII-IIILSAIIGA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 159 IMGLNQISLRLILAYSSINHMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAI 238
Cdd:MTH00160  159 IGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFL 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 239 SFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSLKENKWTKNNFTIKNKTS-FML 317
Cdd:MTH00160  239 NLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLIlNFL 318

                         330
                  ....*....|....*
gi 2130626257 318 NSVSTLGMLMSPLFL 332
Cdd:MTH00160  319 SFISLFGLILSSLLF 333
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 26-278 5.55e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.22  E-value: 5.55e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  26 SWLGVWMGLEINMLSFIPLM---SNKSMYMTSSIKYFITQTLASIALITSFI----------------TLTMNLFNQNKE 86
Cdd:pfam00361   3 DLLLMYLGWEAVLLPSYLLIgywGKSPRSSEAGMKYFLLTLLGSSILLFGISlmynytgtlsfdelskALTGGLNSSGLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  87 IINIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLL-MTWQKIAP-------LVTMSYIEVNQMFMTTIIIMSAIIGA 158
Cdd:pfam00361  83 LLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGyglirrsLLYLPSSPFIQQILLILAIISMLLGS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 159 IMGLNQISLRLILAYSSINHMAWMLASI----QTSMMNWIWYFLIYSLLT-----MIISMSMKNSNINLINEMFIVNNNN 229
Cdd:pfam00361 163 LAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSaglflCAGSVIYRRVHTRNIRDYGGLAKTM 242

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 2130626257 230 KMDKLNSAISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSS 278
Cdd:pfam00361 243 PILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 28-287 1.68e-15

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 76.91  E-value: 1.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  28 LGVWMGLEINMLSFIPLMS--NKSMYMT-SSIKYFITQTLAS------IALI------TSFITLTMNLFNQNKEIIN--- 89
Cdd:TIGR01770 125 LSIYLGLELQSLCFYVLAGlkRKSRFSTeAGLKYFILGAFSSglllfgISLIygftgsLNFEDLLLFLSNGMLNISLlll 204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  90 --IMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTM---------SYIEVNQMFMTTIIIMSAIIGA 158
Cdd:TIGR01770 205 giVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFlrlflyilfGFSEAWQIFLAIIAFLSMLIGN 284

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 159 IMGLNQISLRLILAYSSINHMAWMLASI----QTSMMNWIWYFLIYSLLTM-----IISMSMKNSN-INLINEMFIVNNN 228
Cdd:TIGR01770 285 FGALAQKKVKRLLAYSSISHVGYILIGLlagtLEGIKAVLFYIFIYALMSLgafgvLSLLRSYKDEwIEYISDFAGLFKT 364

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2130626257 229 NKMDKLNSAISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMK 287
Cdd:TIGR01770 365 NPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 54-293 8.39e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 74.77  E-value: 8.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  54 SSIKYFITQTLAS------IALI------TSFITLTMNLfnQNKEIINIMMAMSILM-------KMGAAPVHFWFPEVME 114
Cdd:COG1007   154 AALKYFLLGALSSgfllygISLLygatgsLNLAGIAAAL--AAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYE 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 115 FMEWKNCMLLMTWQKIAPLVTM---------SYIEVNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSINHMAWML-- 183
Cdd:COG1007   232 GAPTPVTAFLATAPKIAAFAALlrllveafpGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLlg 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 184 ------ASIQTSMMnwiwYFLIYSLLT-----MIISMSMKNSNINLINEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGF 252
Cdd:COG1007   312 laagtpLGVSAALF----YLLAYLFMNlgafaVILLLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGF 387

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2130626257 253 MPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMK----MFLSAG 293
Cdd:COG1007   388 FGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRvvkaMYFDEP 432
 
Name Accession Description Interval E-value
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-332 4.24e-74

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 231.64  E-value: 4.24e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257   1 MKKMPMKIMFYTTLITSTLITITATSWLGVWMGLEINMLSFIPLMSNKSMYMT--SSIKYFITQTLASIALITSFITLTM 78
Cdd:MTH00160    1 MMMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSseSSLKYFLIQALASIILLFSIILNML 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  79 NLFNQNKeIINIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYIEVNQMFMTtIIIMSAIIGA 158
Cdd:MTH00160   81 NLMLFNN-ISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINNNFIII-IIILSAIIGA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 159 IMGLNQISLRLILAYSSINHMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAI 238
Cdd:MTH00160  159 IGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFL 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 239 SFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSLKENKWTKNNFTIKNKTS-FML 317
Cdd:MTH00160  239 NLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFSLIlNFL 318

                         330
                  ....*....|....*
gi 2130626257 318 NSVSTLGMLMSPLFL 332
Cdd:MTH00160  319 SFISLFGLILSSLLF 333
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 2-328 2.91e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 167.37  E-value: 2.91e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257   2 KKMPMKIMFYTTLITSTLITITATSWLGVWMGLEINMLSFIPLMSN--KSMYMTSSIKYFITQTLASIALITSFITLTMN 79
Cdd:MTH00144    1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYkkKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  80 LFNQNkeiINIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYI-EVNQMFMTTIII--MSAII 156
Cdd:MTH00144   81 SFSWF---SMSLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFlDLYWLAYLLCVIsvLSALV 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 157 GAIMGLNQISLRLILAYSSINHMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMdKLNS 236
Cdd:MTH00144  158 GSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPSYKT-GLSI 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 237 AISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSLKENKwtKNNFTIKNKTSFM 316
Cdd:MTH00144  237 ISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKK--SNSSKVLNSSIIS 314

                         330
                  ....*....|..
gi 2130626257 317 LNSVSTLGMLMS 328
Cdd:MTH00144  315 LNLLGGLLFLLL 326
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 27-330 5.30e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 164.61  E-value: 5.30e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  27 WLGVWMGLEINMLSFIPLMSNKS--MYMTSSIKYFITQTLASIALITSFITLTMNLFN-----QNKEIINIMMAMSILMK 99
Cdd:MTH00112   26 WLMAWTGLEINTLAIIPLISKPHhpRATEAATKYFLTQAAASALILFSSTTNAWNTGQwditqLTNPTSCTLLTLALAMK 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 100 MGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLV--TMSYIEVNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSIN 177
Cdd:MTH00112  106 LGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTllLMTSNSLNPTLLLTLAILSTLIGGWGGLNQTQLRKIMAFSSIA 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 178 HMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGFMPKWM 257
Cdd:MTH00112  186 HLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLTGFMPKWL 265

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2130626257 258 LIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSLKENKWTKNNFTIKNKTSFMLNSVSTLGMLMSPL 330
Cdd:MTH00112  266 ILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKKNTLTATLTTLSTLLLPL 338
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 26-330 1.96e-44

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 155.13  E-value: 1.96e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  26 SWLGVWMGLEINMLSFIPLMSNKSM--YMTSSIKYFITQTLASIALITSFITLTM-----NLFNQNKEIINIMMAMSILM 98
Cdd:MTH00200   25 HWFLIWLGLEINTLAIIPLLIKQHHprKVEATTKYFIIQATASALLLFGGLLNAWtsgqwGISEMLGPLSETLILLALAL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  99 KMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLV--TMSYIEVNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSI 176
Cdd:MTH00200  105 KLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFAllIQLAPALNSNILLLLGLLSVLVGGWGGLNQTQLRKILAYSSI 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 177 NHMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGFMPKW 256
Cdd:MTH00200  185 AHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSLGGLPPLTGFFPKW 264

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2130626257 257 MLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSLKENKWTKNNFTIKNKTSFMLNSVSTLGMLMSPL 330
Cdd:MTH00200  265 LILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSNSNLLVGLLLLLSILGLPL 338
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 27-330 4.50e-44

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 154.23  E-value: 4.50e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  27 WLGVWMGLEINMLSFIPLMSNKSM--YMTSSIKYFITQTLASIALITSFITLTM-----NLFNQNKEIINIMMAMSILMK 99
Cdd:MTH00105   26 WLLAWIGLEMNMLAIIPILMKKHNprSTEAATKYFLTQATASMLLMMAIIINLMysgqwTITKLTNPTASTLMTIALAMK 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 100 MGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYI--EVNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSIN 177
Cdd:MTH00105  106 LGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQIspSINPNLLLTLAILSILIGGWGGLNQTQLRKILAYSSIA 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 178 HMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGFMPKWM 257
Cdd:MTH00105  186 HMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLGGLPPLTGFMPKWM 265

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2130626257 258 LIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSLKENKWTKNNFTIKN-KTSFMLNSVSTLGMLMSPL 330
Cdd:MTH00105  266 IIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENtKPMTLLPTLIILSTMLLPL 339
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 27-288 2.99e-43

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 152.27  E-value: 2.99e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  27 WLGVWMGLEINMLSFIPLMSNK--SMYMTSSIKYFITQ-TLASIALITS----FITLTMNLFNQNKEIINIMMAMSILMK 99
Cdd:MTH00135   26 WLLAWMGLEINTLAIIPLMAQHhhPRAVEATTKYFLTQaTAAAMILFASttnaWLTGQWDIQQMSHPLPTTMITLALALK 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 100 MGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYIE-VNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSINH 178
Cdd:MTH00135  106 IGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIApTNPTLLITLGLTSTLVGGWGGLNQTQLRKILAYSSIAH 185

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 179 MAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGFMPKWML 258
Cdd:MTH00135  186 LGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLTGFMPKWLI 265

                         250       260       270
                  ....*....|....*....|....*....|
gi 2130626257 259 IQEMMQKCMYSVSVTLIMSSTVTLYFYMKM 288
Cdd:MTH00135  266 LQELTKQDLPLTATLAALSALLSLYFYLRL 295
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 9-297 2.28e-42

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 149.44  E-value: 2.28e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257   9 MFYTTLITSTLITITATSWLGVWMGLEINMLSFIPLMSN--KSMYMTSSIKYFITQTLASIALITSFITLTMNLFNQnkE 86
Cdd:MTH00197    2 LFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQnkSITENEGAMKYFLFQEFGSALLLMGGSLSFSNLYLS--L 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  87 IINIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYIEVNQMFMTTIIIMSAIIGAIMGLNQIS 166
Cdd:MTH00197   80 LSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGMNQSN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 167 LRLILAYSSINHMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAISFLSLGGM 246
Cdd:MTH00197  160 IRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGL 239

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2130626257 247 PPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSL 297
Cdd:MTH00197  240 PPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSN 290
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 27-330 7.42e-42

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 148.53  E-value: 7.42e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  27 WLGVWMGLEINMLSFIPLMSN--KSMYMTSSIKYFITQTLASiALITsFITLTMNLFNQNKEIIN-------IMMAMSIL 97
Cdd:MTH00070   26 WFLAWMGLEINTLAIIPLMTKthHPRATEAATKYFLTQASAS-ALIL-FSSTINAWFTGEWTIMNmqtplptIMLTIALM 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  98 MKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAP--LVTMSYIEVNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSS 175
Cdd:MTH00070  104 MKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPmaLLIQISHLLNSNLLIIMGLLSTLIGGWGGLNQTQLRKIMAYSS 183

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 176 INHMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGFMPK 255
Cdd:MTH00070  184 IAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLGGLPPTTGFIPK 263

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2130626257 256 WMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSLKENKWTKNNFTIKNKTSFMLNSVSTLGMLMSPL 330
Cdd:MTH00070  264 WLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNKTNNLLSLTIILSLMLLPI 338
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 26-332 3.29e-41

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 147.00  E-value: 3.29e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  26 SWLGVWMGLEINMLSFIPLMSN--KSMYMTSSIKYFITQTLASI-----ALITSFITLTMNLFNQNKEIINIMMAMSILM 98
Cdd:MTH00041   25 HWFLIWLGLELNTLSIIPILSSnfSPRSVEATIKYFLVQAFSAAillngALIQAWLSGSWSINGPLNTLSSIIITLALAL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  99 KMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYI--EVNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSI 176
Cdd:MTH00041  105 KLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISIsnLLNSNILILCGILSVLVGGWGGLNQTQTRKILAFSSI 184

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 177 NHMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGFMPKW 256
Cdd:MTH00041  185 AHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLTGFLNKF 264

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 257 MLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSLKENKWTKNNFTIKNKTSF------MLNSVSTLGMLMSPL 330
Cdd:MTH00041  265 ISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNITVygvilsILSSISILGLLLIPL 344


                  ..
gi 2130626257 331 FL 332
Cdd:MTH00041  345 FL 346
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-291 7.46e-40

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 143.00  E-value: 7.46e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257   1 MKKMPMKIMFYTTLITSTLITITATSWLGVWMGLEINMLSFIPLMSNKSMYMTS--SIKYFITQTLASIALITSfITLTM 78
Cdd:MTH00011    2 MSTFPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESeaAVKYFLAQALGSGLLLLG-MTMMW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  79 NLFNQNKEIINIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYI--EVNQMFMTTIIIMSAII 156
Cdd:MTH00011   81 SFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFtsHNILPMMTSMAAMSALA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 157 GAIMGLNQISLRLILAYSSINHMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNS 236
Cdd:MTH00011  161 GGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSL 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2130626257 237 AISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLS 291
Cdd:MTH00011  241 FIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN 295
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 27-288 3.01e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 95.87  E-value: 3.01e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  27 WLGVWMGLEINMLSFIPLMSNKSMYMTS---SIKYFITQTLAS--------------IALITSFITLTMNLFNQNKEII- 88
Cdd:MTH00196   15 WLSVYLAIELQTLSLFILIAQNRGSGYSaeaGLKYFVLGALSSglflfgcallcgttGGLHLSYINLVLNSGQSFSSVSv 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  89 ---NIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYIEVNQMFMTTIIIMSAIIGAIMGLNQI 165
Cdd:MTH00196   95 pigYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFSLFVGAIGALNQT 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 166 SLRLILAYSSINHMAWML--------ASIQTSMMnWIWYFLIYSLLTMIISMSMkNSNINLINEMFIVNNNNKMDKLNSA 237
Cdd:MTH00196  175 KIKRLLAYSGIGHMGFVLwgieigsfESIQASLV-YLFIYIIMSICVFSIILAL-NVYKNLIIEFSGLSRRLPILAITLA 252

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2130626257 238 ISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKM 288
Cdd:MTH00196  253 LTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 26-278 5.55e-21

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 91.22  E-value: 5.55e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  26 SWLGVWMGLEINMLSFIPLM---SNKSMYMTSSIKYFITQTLASIALITSFI----------------TLTMNLFNQNKE 86
Cdd:pfam00361   3 DLLLMYLGWEAVLLPSYLLIgywGKSPRSSEAGMKYFLLTLLGSSILLFGISlmynytgtlsfdelskALTGGLNSSGLL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  87 IINIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLL-MTWQKIAP-------LVTMSYIEVNQMFMTTIIIMSAIIGA 158
Cdd:pfam00361  83 LLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLaATLVKAGGyglirrsLLYLPSSPFIQQILLILAIISMLLGS 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 159 IMGLNQISLRLILAYSSINHMAWMLASI----QTSMMNWIWYFLIYSLLT-----MIISMSMKNSNINLINEMFIVNNNN 229
Cdd:pfam00361 163 LAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSaglflCAGSVIYRRVHTRNIRDYGGLAKTM 242

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 2130626257 230 KMDKLNSAISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSS 278
Cdd:pfam00361 243 PILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 27-288 5.20e-18

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 84.30  E-value: 5.20e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  27 WLGVWMGLEINMLSFIPLMSNK--SMYMT-SSIKYFITQTLAS------IALI------TSFITLTMNLFnqnKEIINIM 91
Cdd:MTH00199  119 WLSIYLAIELQTLTLFILVALKrdSAYSTeAGLKYFVLGAVSSglflfgCALLygltgeTSIQGINSILT---GDVGKIL 195

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  92 MAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAplvtMSYIEVNQMFMTTIIIMSAII----GAIMGLNQISL 167
Cdd:MTH00199  196 ITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIG----VFSILVQIGPVTNVVLICAVLsiiyGAIGALNQTKI 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 168 RLILAYSSINHMAWML--------ASIQTSMMNWIWYfLIYSLLTMIISMSMKNSNiNLINEMFIVNNNNKMDKLNSAIS 239
Cdd:MTH00199  272 KRLLAYSGIGHMGFILfgvaigsfESIQASLIYMIIY-VIMSICSFSIILSLKLTK-GLIVEVSGLSRKNPVIALTLALT 349

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*....
gi 2130626257 240 FLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKM 288
Cdd:MTH00199  350 FLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRV 398
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 28-287 1.68e-15

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 76.91  E-value: 1.68e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  28 LGVWMGLEINMLSFIPLMS--NKSMYMT-SSIKYFITQTLAS------IALI------TSFITLTMNLFNQNKEIIN--- 89
Cdd:TIGR01770 125 LSIYLGLELQSLCFYVLAGlkRKSRFSTeAGLKYFILGAFSSglllfgISLIygftgsLNFEDLLLFLSNGMLNISLlll 204

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  90 --IMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTM---------SYIEVNQMFMTTIIIMSAIIGA 158
Cdd:TIGR01770 205 giVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFlrlflyilfGFSEAWQIFLAIIAFLSMLIGN 284

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 159 IMGLNQISLRLILAYSSINHMAWMLASI----QTSMMNWIWYFLIYSLLTM-----IISMSMKNSN-INLINEMFIVNNN 228
Cdd:TIGR01770 285 FGALAQKKVKRLLAYSSISHVGYILIGLlagtLEGIKAVLFYIFIYALMSLgafgvLSLLRSYKDEwIEYISDFAGLFKT 364

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2130626257 229 NKMDKLNSAISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMK 287
Cdd:TIGR01770 365 NPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLR 423
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 54-293 8.39e-15

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 74.77  E-value: 8.39e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  54 SSIKYFITQTLAS------IALI------TSFITLTMNLfnQNKEIINIMMAMSILM-------KMGAAPVHFWFPEVME 114
Cdd:COG1007   154 AALKYFLLGALSSgfllygISLLygatgsLNLAGIAAAL--AAGGANSPLLLLGLVLvlaglafKLSAVPFHMWTPDVYE 231

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 115 FMEWKNCMLLMTWQKIAPLVTM---------SYIEVNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSINHMAWML-- 183
Cdd:COG1007   232 GAPTPVTAFLATAPKIAAFAALlrllveafpGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLlg 311

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 184 ------ASIQTSMMnwiwYFLIYSLLT-----MIISMSMKNSNINLINEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGF 252
Cdd:COG1007   312 laagtpLGVSAALF----YLLAYLFMNlgafaVILLLSRKGGEAEEIEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGF 387

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2130626257 253 MPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMK----MFLSAG 293
Cdd:COG1007   388 FGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRvvkaMYFDEP 432
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 58-289 4.46e-14

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 72.97  E-value: 4.46e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  58 YF-ITQTLASIALITSFITLTMNLFNQNKEIINIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTM 136
Cdd:MTH00198  270 YFgFTGNEGMLGTILSATLETTNIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILL 349

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 137 SYIEVNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSINHMAWMLASIQTSMMNWI---WYFLIYSLLTMIISMSM-- 211
Cdd:MTH00198  350 TSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLqasWTYAVTYLVSALASFTVic 429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 212 -----------------KNSNINLIN---EMFIVNNNNKMDKLNSAISFLSLGGMPPFIGFMPKWMLIQEmmqkcmysvS 271
Cdd:MTH00198  430 tleefgtrtptsrqrdgSFGNYNLVRrlvDLTILSRGQPYIAFSLAIVFLSLAGIPPLLGFLGKWFILVG---------S 500

                         250
                  ....*....|....*...
gi 2130626257 272 VTLIMSSTVTLYFYMKMF 289
Cdd:MTH00198  501 IKIAFSSSLSIYYLVALF 518
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
90-331 1.01e-12

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 68.69  E-value: 1.01e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  90 IMMAMSILMKMGAAPVHFWFPEVME--------FMEwkncmllmTWQKIAPLVTM---------SYIEVNQMFMTTIIIM 152
Cdd:PRK05777  208 VFLLVGLAFKLSAVPFHMWTPDVYEgaptpvtaFLA--------TAPKIAAFAVLlrllvvafgGLSEDWQQVLAIIAIA 279

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 153 SAIIGAIMGLNQISLRLILAYSSINHMAWML---ASIQTSMMNWIW-YFLIYSLLT-----MIISMSMKNSNINLINEMF 223
Cdd:PRK05777  280 SMLVGNLAALSQTNIKRLLAYSSIAHAGYLLvglAAGTAEGYSAVLfYLLAYLFMTlgafgVISLLRRKGGEAESISDFA 359

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 224 IVNNNNKMDKLNSAISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMK----MFLSAgllslKE 299
Cdd:PRK05777  360 GLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRviklMYFDE-----PP 434

                         250       260       270
                  ....*....|....*....|....*....|....
gi 2130626257 300 NKWTKNNFTIKNKTSFMLNSVST--LGMLMSPLF 331
Cdd:PRK05777  435 RDAPVNWPLSAGGAVLSVSALLVlvLGIFPQPLL 468
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 144-291 7.73e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 59.98  E-value: 7.73e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 144 MFMTTIIIM---SAIIGAIMGLNQISLRLILAYSSINHMAWMLASIQTSMMNWIWYFLIY--------SLLTMIISMSMK 212
Cdd:PRK12667  293 ALSPILIILgavSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHiinhaiakSLLFLASGVFIH 372

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2130626257 213 NSNINLINEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLS 291
Cdd:PRK12667  373 AAGTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 55-293 5.52e-09

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 57.08  E-value: 5.52e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  55 SIKYFITQTLASIALITSFI-------TLTMNLFNQN--------KEIINIMMAMSILMKMGAAPVHFWFPE-------- 111
Cdd:COG0651   159 GLKYLILNLVGSALFLLGVGllygatgTLNMADLAARlaeldpglLLAAFALLLVGFGIKAALFPLHFWLPDaypaapsp 238

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 112 -------VMefmewKNCM---LLMTWQKIAPLVTMSYIevnQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSINHMAW 181
Cdd:COG0651   239 vsallsgLL-----TKVGvyaILRVLTLLFGADPALFL---GTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGY 310

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 182 MLASI---QTSMMNWIWYFLIYSLLTM--------IISMSMKNSNINLINEMFivnnnNKMDKLNSA--ISFLSLGGMPP 248
Cdd:COG0651   311 ILLGLglgTPLGLAGALFHLLNHALAKallflaagAIERATGTRDLDKLGGLG-----KRMPLTAAAflIGALALAGLPP 385

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2130626257 249 FIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAG 293
Cdd:COG0651   386 LSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 148-286 2.08e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 55.27  E-value: 2.08e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 148 TIIIMSAIIGAIMGLNQISLRLILAYSSINHMAWMLASI----QTSMMNWIWYFLIYSL----LTMIISMSMKNSNINLI 219
Cdd:PRK08375  276 VLALLSMLVGSLAALGQDDVKRVLAYSTVSQMGYILLGLalltPLALAAGLLHLLHHALmkgaLFLAAGAIEVTYGTRRL 355

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2130626257 220 NEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLyFYM 286
Cdd:PRK08375  356 SELSGLGRRMPLTAAAFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLAL-LYF 421
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
95-287 3.16e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 51.59  E-value: 3.16e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  95 SILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAP-------LVTM--SYIEVNQMFMTTIIIMSAIIGAIMGLNQI 165
Cdd:PRK02504  219 GIAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGfalairlLVTAfpSFDEQWKLLFTALAILSMVLGNVVALAQT 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 166 SLRLILAYSSINH----MAWMLASIQTSMMNWIWYFLIYSLL-----TMIISMSMKNSNiNLINEMFIVNNNNKMDKLNS 236
Cdd:PRK02504  299 SMKRMLAYSSIGQagfvMIGLVAGTEAGYASMVFYLLAYLFMnlgafACVILFSLRTGT-DQISDYAGLYQKDPLLTLGL 377

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2130626257 237 AISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMK 287
Cdd:PRK02504  378 SLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIR 428
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 89-307 1.62e-05

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 45.63  E-value: 1.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  89 NIMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPLVTMSYIEVNQMFMttIIIMSAIIGAIMGLNQISLR 168
Cdd:MTH00091   60 GYFQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFF--LLLFGLLICFFQMFLLKSYK 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 169 LILAYSSINHMAWMLASIQTSMMNWIWYFLIYSLLTMIISMSMKNSNINLINEMFIVnnnnkmdklnsaisfLSLGGMPP 248
Cdd:MTH00091  138 NLLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLIPKFNNVNKLNFVSWETL---------------LVFMNLPF 202

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2130626257 249 FIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSAGLLSLKENKWTKNNF 307
Cdd:MTH00091  203 SVTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFF 261
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 54-292 2.09e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 45.86  E-value: 2.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  54 SSIKYFITQTLAS------IALI-TSFITLTM---------NLFNQNKEIINIMMAmSILMKMGAAPVHFWFPEVM-EFM 116
Cdd:PRK08376  173 AGIKYMFVGSLASsmvllgIALLyGQYGTLNMaylavkmseNPTVVAKIALALFIA-GLAMKSGAVPVHMWLPDAYpAAP 251

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 117 EWKNCMLLMTwqKIAPLVTMSYI-------EVNQMFMTTIII----MSAIIGAIMGLNQISLRLILAYSSINHMAWMLAS 185
Cdd:PRK08376  252 SSISAMLLVI--KQAGLYALARVlfsiygpAINLATVGWVIIilgcLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYMLLG 329

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 186 I----------------QTSMMNWIW----YFLIYSLLTMIISMSMKNSNINLINEMFIVNNNNKMDKLNSAISFLSLGG 245
Cdd:PRK08376  330 LgvglaalgdpamasygEIALAGGIYhivnHALYKALLFLTAGAVIYETGTRNLNELGGLARTMPKTTIAFLIGAAAIVG 409

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 2130626257 246 MPPFIGFMPKWmLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLSA 292
Cdd:PRK08376  410 LPPFNGFASKW-LIYESSALFNPILGVIAMIGSVLTLASFVKVFHTA 455
ndhB CHL00049
NADH dehydrogenase subunit 2
 90-287 5.23e-05

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 44.61  E-value: 5.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257  90 IMMAMSILMKMGAAPVHFWFPEVMEFMEWKNCMLLMTWQKIAPL--------VTMSYIEVNQMFMTTII-IMSAIIGAIM 160
Cdd:CHL00049  218 IFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASalatrifdIPFYFSSNEWHLLLEILaILSMILGNLI 297

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 161 GLNQISLRLILAYSSINHMAWMLASIQTSMMNW-----IWYFLIYSLLTM-----IISMSMKNSNINlINEMFIVNNNNK 230
Cdd:CHL00049  298 AITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDgyasmITYMLFYIFMNLgtfacIVLFGLRTGTDN-IRDYAGLYTKDP 376

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2130626257 231 MDKLNSAISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMK 287
Cdd:CHL00049  377 FLALSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLK 433
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 140-292 8.93e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 44.17  E-value: 8.93e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 140 EVNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSINHMAWMLASI----QTSMMNWIWY----FLIYSLLTMIISMSM 211
Cdd:PRK07691  272 SFTHYLILILALLTIIFGVIGAVAYFDIKKIIIYNIMIAVGVILVGVammtESGMIGAIYYlihdMIVKAALFLLIGIMI 351

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 212 KNSNINLINEMFIVNNNNKMDKLNSAISFLSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYMKMFLS 291
Cdd:PRK07691  352 KITGTTDLKKMGGLIKRYPVLGWMFFIAALSLAGIPPLSGFYGKFFIVEGTFEAGFYVSGIIVLLSSLLVLYSVIKIFLK 431


                  .
gi 2130626257 292 A 292
Cdd:PRK07691  432 G 432
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
136-291 1.97e-04

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 43.10  E-value: 1.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 136 MSYIEVNQMFMTTIIIMSAIIGAIMGLNQISLRLILAYSSINHMAWMLASIQTSMMNWIWYFLIYSLLTMIISmSMKNSN 215
Cdd:PRK06277  259 LSYFPSAQGVLIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYVAAGLALGTPLGIVAGIFHAINHVIYK-SALFLG 337

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2130626257 216 INLINEMFIVNNNNKMDKLNSAISF---------LSLGGMPPFIGFMPKWMLIQEMMQKCMYSVSVTLIMSSTVTLYFYM 286
Cdd:PRK06277  338 AGIVSYRTKTSNLRKLGGLLPVMPVvafmvlcakLAISGVPPFNGFQSKLMLAQAAMQANMPELAIIMIIVSIGTFVSMM 417


                  ....*
gi 2130626257 287 KMFLS 291
Cdd:PRK06277  418 KAFYL 422
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH