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Conserved domains on  [gi|2127473031|ref|WP_227650940|]
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ABC transporter permease [Klebsiella pneumoniae]

Protein Classification

ABC transporter permease( domain architecture ID 10003058)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates such as monosaccharide sugars such as xylose, arabinose, and fructose

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 6-306 1.69e-78

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440785  Cd Length: 322  Bit Score: 241.55  E-value: 1.69e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031   6 CLLLGWRSEEFFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIG 85
Cdd:COG1172    29 LVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVVALSGVVAALLLVALGLPILLAILLALLVG 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  86 VLLGLVNALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFekgvmlfkYTDADGYDYGLGLPLLTMIAVVL 165
Cdd:COG1172   109 ALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLTGGRPISGLPDAF--------RALGQGSLLGIPVPVLIALVVAL 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 166 LTAFIMNFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLG 245
Cdd:COG1172   181 VAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPNAGSGYELDAIAAVVIG 260

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2127473031 246 GTSLIGGRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVVSISVTAWSQHQNR 306
Cdd:COG1172   261 GTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGAIILLAVLLDRLRRRRRA 321
 
Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 6-306 1.69e-78

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440785  Cd Length: 322  Bit Score: 241.55  E-value: 1.69e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031   6 CLLLGWRSEEFFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIG 85
Cdd:COG1172    29 LVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVVALSGVVAALLLVALGLPILLAILLALLVG 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  86 VLLGLVNALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFekgvmlfkYTDADGYDYGLGLPLLTMIAVVL 165
Cdd:COG1172   109 ALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLTGGRPISGLPDAF--------RALGQGSLLGIPVPVLIALVVAL 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 166 LTAFIMNFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLG 245
Cdd:COG1172   181 VAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPNAGSGYELDAIAAVVIG 260

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2127473031 246 GTSLIGGRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVVSISVTAWSQHQNR 306
Cdd:COG1172   261 GTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGAIILLAVLLDRLRRRRRA 321
TM_PBP1_transp_AraH_like cd06579
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ...
 30-298 5.44e-71

Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.


Pssm-ID: 119321 [Multi-domain]  Cd Length: 263  Bit Score: 220.36  E-value: 5.44e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  30 AMLTILACGLFVVLIAGGIDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIGVLLGLVNALLVNRLRVPSIIITIS 109
Cdd:cd06579     2 AVLGILALGMTLVIITGGIDLSVGSVAALSAVVAALLLVNAGLPIPLAILAALAVGALIGLLNGLLVAYLRIPPFIVTLG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 110 TLNIFYGLLLWLSKGVWLYDFPPWFekgvmlfKYTDADGYDYGLGLPLLTMIAVVLLTAFIMNFTTVGRKIYAMGGNRES 189
Cdd:cd06579    82 TMFILRGLALLITGGRPISGLPPLF-------SFFLGGGLILGIPVPVLIALAVALVAWFLLRRTRFGRYLYAVGGNPEA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 190 ASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGGTSLIGGRGTLSGTLLGVILLAVM 269
Cdd:cd06579   155 ARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPTAGNGYELDAIAAVVLGGTSLTGGRGSVLGTLLGALLLGVL 234

                         250       260
                  ....*....|....*....|....*....
gi 2127473031 270 QNGLNLLGVSSYWQTLITGAIIVVSISVT 298
Cdd:cd06579   235 NNGLNLLGVSSFWQQIVKGAILLLAVALD 263
PRK09699 PRK09699
D-allose ABC transporter permease;
13-297 5.86e-39

D-allose ABC transporter permease;


Pssm-ID: 182035 [Multi-domain]  Cd Length: 312  Bit Score: 139.14  E-value: 5.86e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  13 SEEFFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISFPAmtIIAQYGMVVMLQKVGGNFAVAFVLAGGI--GVLLGL 90
Cdd:PRK09699   30 PEYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGA--ILALSGMVTAKLMLAGVDPFLAALIGGVlvGGALGA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  91 VNALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPpwfekgvmlFKYTDADGYD-YGLGLPLLTMIAVVLLTAF 169
Cdd:PRK09699  108 INGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYGFS---------FDFVNFFAASvIGIPVPVIFSLIVALILWF 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 170 IMNFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGGTSL 249
Cdd:PRK09699  179 LTTRMRLGRNIYALGGNKNSAFYSGIDVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSF 258

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2127473031 250 IGGRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVVSISV 297
Cdd:PRK09699  259 FGGKGRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVAL 306
GguB NF040906
sugar ABC transporter permease;
21-290 3.51e-27

sugar ABC transporter permease;


Pssm-ID: 468841 [Multi-domain]  Cd Length: 375  Bit Score: 109.09  E-value: 3.51e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  21 NIYDLANNYAMLTILACGLFVVLIAGGIDISfpAMTIIAQYGMV--VMLQKVGGNFAVAFVLAGGIGVLLGLVNALLVNR 98
Cdd:NF040906   31 NVTNLILQNSYILILAIGMLLVIIAGHIDLS--VGSVVAFVGAVaaVLMVNWGMPWWLAVLLCLLVGALIGAWQGFWVAY 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  99 LRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEK------------------------------------------ 136
Cdd:NF040906  109 VGIPAFIVTLAGMLVFRGLTLVVLGGQSIGPFPDGFQKissgflpdlfggtglhlltlllgvlaaaalvwsqlrgrrrri 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 137 ---------------------GVMLFKYTDADGYdyGLGLPLLTMIAVVLLTAFIMNFTTVGRKIYAMGGNRESASRVGF 195
Cdd:NF040906  189 kyglevepmalfiaklvliaaAILFFTYLLASYR--GLPNVLIILGVLILVYSFVTNRTVIGRHIYAVGGNEKAAKLSGI 266

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 196 SVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGGTSLIGGRGTLSGTLLGVILLAVMQNGLNL 275
Cdd:NF040906  267 KTKRVTFLVFVNMGVLAALAGLVFAARLNSATPKAGNGFELDAIAACFIGGASASGGVGTVVGAIIGALVMGVLNNGMSI 346

                         330
                  ....*....|....*
gi 2127473031 276 LGVSSYWQTLITGAI 290
Cdd:NF040906  347 LGIGIDWQQVIKGLV 361
BPD_transp_2 pfam02653
Branched-chain amino acid transport system / permease component; This is a large family mainly ...
 21-294 3.65e-20

Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.


Pssm-ID: 396977 [Multi-domain]  Cd Length: 269  Bit Score: 88.08  E-value: 3.65e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  21 NIYDLANNYAMLTILACGL-FVVLIAGGIDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIGVLLGLVNALLVNRL 99
Cdd:pfam02653   1 NILNILTLASIYAIAALGLtLIYGIAGVINLGHGGFMMLGAYVAAMLLNLLGPGLWLALPVGILVGAAVGLLIGILTLRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 100 RVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEKGVMLFKYTDADgydYGLGLPLLTMIAVVLLTAFIMNFTTVGRK 179
Cdd:pfam02653  81 KINEVIITLLLNLAALGLALFLVTGILGGEGGTSGITGPSGFPGAFLS---FAFAFIFLLALLLVLALWLLLYRTKFGRA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 180 IYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDS-LLGYELTVLAAVVlggtslIGGRGTLSG 258
Cdd:pfam02653 158 LRAVGENEEAARAAGINVKKLKLLTFVISGALAGLAGALLALYTGVVPPSNfGVGLGLDAIAAVV------LGGAGSPIG 231

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2127473031 259 TLLGVILLAVMQN-GLNLLGVSSYWQTLITGAIIVVS 294
Cdd:pfam02653 232 VVIGSLIIGLVQSlGLGALGSPPELSLLVLGALLILV 268
 
Name Accession Description Interval E-value
AraH COG1172
Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component ...
 6-306 1.69e-78

Ribose/xylose/arabinose/galactoside ABC-type transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440785  Cd Length: 322  Bit Score: 241.55  E-value: 1.69e-78
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031   6 CLLLGWRSEEFFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIG 85
Cdd:COG1172    29 LVVFSILSPGFLSPGNLSNILRQAAILGILALGMTLVIITGGIDLSVGSVVALSGVVAALLLVALGLPILLAILLALLVG 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  86 VLLGLVNALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFekgvmlfkYTDADGYDYGLGLPLLTMIAVVL 165
Cdd:COG1172   109 ALLGLLNGLLVAKLRIPPFIVTLGTMFIARGLALLLTGGRPISGLPDAF--------RALGQGSLLGIPVPVLIALVVAL 180

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 166 LTAFIMNFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLG 245
Cdd:COG1172   181 VAWFLLRRTRFGRYIYAVGGNEEAARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPNAGSGYELDAIAAVVIG 260

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2127473031 246 GTSLIGGRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVVSISVTAWSQHQNR 306
Cdd:COG1172   261 GTSLTGGRGSVLGTLLGALILGVLNNGLNLLGVSSYWQQIVKGAIILLAVLLDRLRRRRRA 321
TM_PBP1_transp_AraH_like cd06579
Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the ...
 30-298 5.44e-71

Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group also contains E. coli RbsC, AlsC, and MglC, which are TMs of other monosaccharide transporters, the ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also be involved in low affinity ribose transport. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Proteins in this subgroup have a single TM which homodimerizes to generate the transmembrane pore.


Pssm-ID: 119321 [Multi-domain]  Cd Length: 263  Bit Score: 220.36  E-value: 5.44e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  30 AMLTILACGLFVVLIAGGIDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIGVLLGLVNALLVNRLRVPSIIITIS 109
Cdd:cd06579     2 AVLGILALGMTLVIITGGIDLSVGSVAALSAVVAALLLVNAGLPIPLAILAALAVGALIGLLNGLLVAYLRIPPFIVTLG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 110 TLNIFYGLLLWLSKGVWLYDFPPWFekgvmlfKYTDADGYDYGLGLPLLTMIAVVLLTAFIMNFTTVGRKIYAMGGNRES 189
Cdd:cd06579    82 TMFILRGLALLITGGRPISGLPPLF-------SFFLGGGLILGIPVPVLIALAVALVAWFLLRRTRFGRYLYAVGGNPEA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 190 ASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGGTSLIGGRGTLSGTLLGVILLAVM 269
Cdd:cd06579   155 ARLSGINVRRVKILAYVLSGLLAGLAGILLAARLGSAQPTAGNGYELDAIAAVVLGGTSLTGGRGSVLGTLLGALLLGVL 234

                         250       260
                  ....*....|....*....|....*....
gi 2127473031 270 QNGLNLLGVSSYWQTLITGAIIVVSISVT 298
Cdd:cd06579   235 NNGLNLLGVSSFWQQIVKGAILLLAVALD 263
XylH COG4214
ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism];
16-307 3.32e-46

ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443360 [Multi-domain]  Cd Length: 393  Bit Score: 160.28  E-value: 3.32e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  16 FFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISfpAMTIIAQYGMV--VMLQKVGGNFAVAFVLAGGIGVLLGLVNA 93
Cdd:COG4214    46 FLTPRNLSNLLLQNSYIGILAIGMVLVILLGHIDLS--VGSVSGFVGAVaaVLMVNWGLPWWLAILAALLVGALIGAWQG 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  94 LLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEK------------------------------------- 136
Cdd:COG4214   124 FWVAYVGIPSFIVTLAGMLAFRGLTLLVLGGGTIAPFDPTFQAigngflpdilgtlswvlgavavaayvalqlrsrrrrr 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 137 ---------------------GVMLFKYTDADgyDYGLGLPLLTMIAVVLLTAFIMNFTTVGRKIYAMGGNRESASRVGF 195
Cdd:COG4214   204 ryglpveplwlfvlklallavLILGAVYLLNS--YRGIPIVVLILLVLVVVYTFVLTRTVFGRHIYAVGGNPEAARLSGI 281

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 196 SVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGGTSLIGGRGTLSGTLLGVILLAVMQNGLNL 275
Cdd:COG4214   282 NVRRVTFSVFVNMGVLAALAGIVFAARLNSATPSAGTGFELDAIAAAVIGGTSLFGGVGTVYGAVIGALVMGSLNNGMSL 361

                         330       340       350
                  ....*....|....*....|....*....|..
gi 2127473031 276 LGVSSYWQTLITGAIIVVSISVTAWSQHQNRS 307
Cdd:COG4214   362 LGVDSDWQQIVKGLVLLLAVAFDVLSRRRRGA 393
COG4158 COG4158
Predicted ABC-type sugar transport system, permease component [General function prediction ...
 6-302 1.79e-45

Predicted ABC-type sugar transport system, permease component [General function prediction only];


Pssm-ID: 443324  Cd Length: 334  Bit Score: 157.01  E-value: 1.79e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031   6 CLLLGWRSEEFFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISFPAmtIIAQYGMVVMLQKVGGNFAVAFVLAG-GI 84
Cdd:COG4158    40 CIGFELLTPNFLTVQNLSNIARQASINIVLAAGMTFVILTGGIDLSVGS--ILAASAVVAVLVSLLPGLGLLGIPAAlLV 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  85 GVLLGLVNALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEkgvmlfkytdADGYDYGLGLPLLTMIA-- 162
Cdd:COG4158   118 GLLFGLINGLLIAFLKLPPFIVTLGSLTALRGAARLLANGTTVFNPDLPFA----------WIGNGYLLGIPWLVVIAla 187

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 163 VVLLTAFIMNFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSL-LGYELTVLAA 241
Cdd:COG4158   188 VVLASWFILRRTVLGVHIYAVGGNAQAARLTGIKVWRVLLFVYAVSGLLAGLGGVMSAARLYAANGLQLgQGYELDAIAA 267

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2127473031 242 VVLGGTSLIGGRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVVSISVTAWSQ 302
Cdd:COG4158   268 VILGGTSFVGGIGSIWGTLIGALIIAVLNNGLILLGVSDFWQFIIKGLVIIIAVALDRYRQ 328
PRK09699 PRK09699
D-allose ABC transporter permease;
13-297 5.86e-39

D-allose ABC transporter permease;


Pssm-ID: 182035 [Multi-domain]  Cd Length: 312  Bit Score: 139.14  E-value: 5.86e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  13 SEEFFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISFPAmtIIAQYGMVVMLQKVGGNFAVAFVLAGGI--GVLLGL 90
Cdd:PRK09699   30 PEYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGA--ILALSGMVTAKLMLAGVDPFLAALIGGVlvGGALGA 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  91 VNALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPpwfekgvmlFKYTDADGYD-YGLGLPLLTMIAVVLLTAF 169
Cdd:PRK09699  108 INGCLVNWTGLHPFIITLGTNAIFRGITLVISDANSVYGFS---------FDFVNFFAASvIGIPVPVIFSLIVALILWF 178

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 170 IMNFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGGTSL 249
Cdd:PRK09699  179 LTTRMRLGRNIYALGGNKNSAFYSGIDVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSF 258

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*...
gi 2127473031 250 IGGRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVVSISV 297
Cdd:PRK09699  259 FGGKGRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVAL 306
araH PRK11285
L-arabinose transporter permease protein; Provisional
 16-307 1.40e-38

L-arabinose transporter permease protein; Provisional


Pssm-ID: 183076 [Multi-domain]  Cd Length: 333  Bit Score: 138.66  E-value: 1.40e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  16 FFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISfpAMTIIAQYGMV-VMLQKVGGNFAVAFVLAGGIGVLLGLVNAL 94
Cdd:PRK11285   50 FASFINMKGLGLAISMIGMVACTMLFCLASGDFDLS--VASVVAFAGVVtAVVINATESLWLGVAAGLLLGAAVGLVNGF 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  95 LVNRLRVPSIIITISTLNIFYGLLLWLSKGvwlydfppwfeKGVMLFK---YTDADGYDYGLGLPLLTMIAVVLLTAFIM 171
Cdd:PRK11285  128 VIARLKINALITTLATMQIVRGLAYIISDG-----------KAVGISDerfFALGYANFFGVPAPIWLTVACFVVFGFLL 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 172 NFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGGTSLIG 251
Cdd:PRK11285  197 NKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLQGLVSALAGVILASRMTSGQPMTSIGFELIVISACVLGGVSLKG 276

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2127473031 252 GRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVVSISVTAWSQHQNRS 307
Cdd:PRK11285  277 GIAKISGVVAGVLILGTVENAMNLLNISPFYQYVVRGLILLAAVLFDRYKQRAKRT 332
rbsC PRK09512
ribose ABC transporter permease protein; Reviewed
 13-297 2.23e-38

ribose ABC transporter permease protein; Reviewed


Pssm-ID: 181922 [Multi-domain]  Cd Length: 320  Bit Score: 137.93  E-value: 2.23e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  13 SEEFFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISfpAMTIIAQYGMVVM-LQKVGGNFAVAFVLAGGIGVLLGLV 91
Cdd:PRK09512   36 SPNFFTVNNLFNILQQTSVNAIMAVGMTLVILTSGIDLS--VGSLLALTGAVAAsIVGIEVNALVAVPAALALGAAIGAV 113

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  92 NALLVNRLRVPSIIITISTLNIFYGLLLWLSKGvwlYDFPPWFEKGVMLFKYTdADGYDYGLGLPLLTMIAVVLLTAFIM 171
Cdd:PRK09512  114 TGVIVAKGKVQAFIATLVMMLLLRGVTMVYTDG---SPINTGFTDNADLFGWF-GIGRPLGIPTPVWIMAIVFLAAWYML 189

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 172 NFTTVGRKIYAMGGNrESASRV-GFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGGTSLI 250
Cdd:PRK09512  190 HHTRLGRYIYALGGN-EAATRLsGINVNKVKIIVYALCGLLAALAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLA 268

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 2127473031 251 GGRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVVSISV 297
Cdd:PRK09512  269 GGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLV 315
GguB NF040906
sugar ABC transporter permease;
21-290 3.51e-27

sugar ABC transporter permease;


Pssm-ID: 468841 [Multi-domain]  Cd Length: 375  Bit Score: 109.09  E-value: 3.51e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  21 NIYDLANNYAMLTILACGLFVVLIAGGIDISfpAMTIIAQYGMV--VMLQKVGGNFAVAFVLAGGIGVLLGLVNALLVNR 98
Cdd:NF040906   31 NVTNLILQNSYILILAIGMLLVIIAGHIDLS--VGSVVAFVGAVaaVLMVNWGMPWWLAVLLCLLVGALIGAWQGFWVAY 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  99 LRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEK------------------------------------------ 136
Cdd:NF040906  109 VGIPAFIVTLAGMLVFRGLTLVVLGGQSIGPFPDGFQKissgflpdlfggtglhlltlllgvlaaaalvwsqlrgrrrri 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 137 ---------------------GVMLFKYTDADGYdyGLGLPLLTMIAVVLLTAFIMNFTTVGRKIYAMGGNRESASRVGF 195
Cdd:NF040906  189 kyglevepmalfiaklvliaaAILFFTYLLASYR--GLPNVLIILGVLILVYSFVTNRTVIGRHIYAVGGNEKAAKLSGI 266

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 196 SVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGGTSLIGGRGTLSGTLLGVILLAVMQNGLNL 275
Cdd:NF040906  267 KTKRVTFLVFVNMGVLAALAGLVFAARLNSATPKAGNGFELDAIAACFIGGASASGGVGTVVGAIIGALVMGVLNNGMSI 346

                         330
                  ....*....|....*
gi 2127473031 276 LGVSSYWQTLITGAI 290
Cdd:NF040906  347 LGIGIDWQQVIKGLV 361
PRK15432 PRK15432
autoinducer 2 ABC transporter permease LsrC; Provisional
 7-292 2.80e-26

autoinducer 2 ABC transporter permease LsrC; Provisional


Pssm-ID: 185330 [Multi-domain]  Cd Length: 344  Bit Score: 105.97  E-value: 2.80e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031   7 LLLGWRSEEFFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISFPAMTIIAQYGMVVMLQKvGGNFAVAFVLAGGIGV 86
Cdd:PRK15432   22 VLLGFLDRQYLSLQTLTMVFSSAQILILLAIGATLVMLTRNIDVSVGSITGLCAVLVGMLLNA-GYSLPVACLATLLLGL 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  87 LLGLVNALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEkgvmlfkyTDADGYDYGLGLPLLTMIAVVLL 166
Cdd:PRK15432  101 LAGFFNGVLVAWLRIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELK--------QLSAPILLGISPIGWLTLILILA 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 167 TAFIMNFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGG 246
Cdd:PRK15432  173 MAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGLEMKAIAACVLGG 252

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 2127473031 247 TSLIGGRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIV 292
Cdd:PRK15432  253 ISLLGGSGTIIGAVLGAYFLTQIDSVLVLLRIPAWWNDFIAGLVLL 298
PRK11618 PRK11618
inner membrane ABC transporter permease protein YjfF; Provisional
 16-295 1.17e-25

inner membrane ABC transporter permease protein YjfF; Provisional


Pssm-ID: 183235 [Multi-domain]  Cd Length: 317  Bit Score: 103.88  E-value: 1.17e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  16 FFTFGNIYDLANNYAMLTILACGLFVVLIAGGIDISFPAmtIIAQYGMV--VMLQKVGGNFAVAFVLAGGIGVLLGLVNA 93
Cdd:PRK11618   29 FASTRVICNLLTDNAFLGIVAVGMTFVILSGGIDLSVGS--VIAFTGVFlaKLIGDYGWSPLLAFPLVLVMGAAFGAFMG 106

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  94 LLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEKGVMLFKYTDadgyDYGLGLPLLTMIAVVLLTAFIMNF 173
Cdd:PRK11618  107 ALIHYLKLPAFIVTLAGMFLARGVSFLVSEESIPINHPFYDTLSSLAWKLPG----GGRLSAMALIMLAVVAIGIFLAHR 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 174 TTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVqaWTVMTVAPDSL--LGYELTVLAAVVLGGTSLIG 251
Cdd:PRK11618  183 TRFGNNVYAIGGNATSANLMGIPVRRTTIRIYMLSGFLATLAGIV--FSLYTSAGYALaaVGVELDAIAAVVIGGTLLTG 260

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2127473031 252 GRGTLSGTLLGVILLAVMQNGLNLLG-VSSYWQTLITGAIIVVSI 295
Cdd:PRK11618  261 GVGTVLGTLFGVLIQGLIQTYITFDGtLSSWWTKIVIGILLFVFI 305
mglC PRK09478
galactose/methyl galactoside ABC transporter permease MglC;
76-297 7.83e-25

galactose/methyl galactoside ABC transporter permease MglC;


Pssm-ID: 181892 [Multi-domain]  Cd Length: 336  Bit Score: 102.07  E-value: 7.83e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  76 VAFVLAGGIGVLLGLVNALLVNRLRVPSIIITISTLNIFYGLllwlskGVWLYDFPPWFEKGVMLFKYTD-ADGYDY--G 152
Cdd:PRK09478  107 LVILIVCAIGAVIGLINGLIIAYLNVTPFIATLGTMIIVYGI------NSLYYDFVGASPISGFDSGFSTfAQGFVAlgS 180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 153 LGLPLLTMIA--VVLLTAFIMNFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDS 230
Cdd:PRK09478  181 FRLSYITFYAliAVAFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVPLNLLMIYALSGVFYAFGGMLEAGRIGSATNNL 260

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2127473031 231 LLGYELTVLAAVVLGGTSLIGGRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVVSISV 297
Cdd:PRK09478  261 GFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVAL 327
BPD_transp_2 pfam02653
Branched-chain amino acid transport system / permease component; This is a large family mainly ...
 21-294 3.65e-20

Branched-chain amino acid transport system / permease component; This is a large family mainly comprising high-affinity branched-chain amino acid transporter proteins such as E. coli LivH and LivM, both of which are form the LIV-I transport system. Also found with in this family are proteins from the galactose transport system permease and a ribose transport system.


Pssm-ID: 396977 [Multi-domain]  Cd Length: 269  Bit Score: 88.08  E-value: 3.65e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  21 NIYDLANNYAMLTILACGL-FVVLIAGGIDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIGVLLGLVNALLVNRL 99
Cdd:pfam02653   1 NILNILTLASIYAIAALGLtLIYGIAGVINLGHGGFMMLGAYVAAMLLNLLGPGLWLALPVGILVGAAVGLLIGILTLRL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 100 RVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEKGVMLFKYTDADgydYGLGLPLLTMIAVVLLTAFIMNFTTVGRK 179
Cdd:pfam02653  81 KINEVIITLLLNLAALGLALFLVTGILGGEGGTSGITGPSGFPGAFLS---FAFAFIFLLALLLVLALWLLLYRTKFGRA 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 180 IYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDS-LLGYELTVLAAVVlggtslIGGRGTLSG 258
Cdd:pfam02653 158 LRAVGENEEAARAAGINVKKLKLLTFVISGALAGLAGALLALYTGVVPPSNfGVGLGLDAIAAVV------LGGAGSPIG 231

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 2127473031 259 TLLGVILLAVMQN-GLNLLGVSSYWQTLITGAIIVVS 294
Cdd:pfam02653 232 VVIGSLIIGLVQSlGLGALGSPPELSLLVLGALLILV 268
PRK15038 PRK15038
autoinducer 2 ABC transporter permease LsrD;
34-305 5.92e-19

autoinducer 2 ABC transporter permease LsrD;


Pssm-ID: 184998  Cd Length: 330  Bit Score: 85.65  E-value: 5.92e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  34 ILACGLFVVLIAGGIDISFPAMTIIAQYGMVVMLQkVGGNFAVAFVLAGGIGVLLGLVNALLVNRLRVPSIIITISTLNI 113
Cdd:PRK15038   47 IVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQ-SGVPMPLAILLTLLLGALCGLINAGLIIYTGVNPLVITLGTLYL 125

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 114 FYGLLLWLS--KGVWLYD----FPPWFekgvmlfkyTD-ADGYDYGLGLPLLTMIAVVLLTAFIMNFTTVGRKIYAMGGN 186
Cdd:PRK15038  126 FGGSALLLSgmAGATGYEgiggFPMAF---------TDfANLDVLGLPVPLIIFLICLLVFWLLMHRTHAGRNVFLIGQS 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 187 RESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSLLGYELTVLAAVVLGGTSLIGGRGTLSGTLLGVILL 266
Cdd:PRK15038  197 PRVALYSAIPVNRTLCALYAMTGLASAIAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTALAVLLV 276

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 2127473031 267 AVMQNGLNLLGVSSYWQTLITGAIIVVSISVTAWSQHQN 305
Cdd:PRK15038  277 GYLQQGLQMAGVPNQISSALSGALLIVVVVGRSVSLHRH 315
LivM COG4177
ABC-type branched-chain amino acid transport system, permease component [Amino acid transport ...
 24-293 1.68e-14

ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443336 [Multi-domain]  Cd Length: 285  Bit Score: 72.04  E-value: 1.68e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  24 DLANNYAMLTILACGLFVVL-IAGGIDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIGVLLGLVNALLVNRLR-V 101
Cdd:COG4177     6 SLLTLILIYAILALGLNLLLgYTGLLSLGHAAFFGIGAYAAALLTTHLGLPFWLALLLAGLVAALLGLLIGLPALRLRgD 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 102 PSIIITISTLNIFYGLLL---WLSKGVW-LYDFPPWFEKGVMLfkytDADGYDYGLGLPLLtmIAVVLLTAFIMNfTTVG 177
Cdd:COG4177    86 YLAIATLAFAEIVRLLALnleSLTGGADgLSGIPRPTLFGLDL----GSPLAFYYLVLALL--VLVLLLLRRLVR-SRFG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 178 RKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSlLGYELTVLAAVVLggtsLIGGRGTLS 257
Cdd:COG4177   159 RALRAIRENEIAAEALGINVTRYKLLAFVLSAALAGLAGALYAHYVGFVSPES-FSFLLSIEILLMV----VLGGLGSLL 233

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 2127473031 258 GTLLGVILLAVMQNGLNLLGvssYWQTLITGAIIVV 293
Cdd:COG4177   234 GPVLGAVLLVLLPELLRSLP---EYRLLIFGLLLIL 266
TM_PBP1_LivM_like cd06581
Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two ...
 29-293 1.96e-12

Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.


Pssm-ID: 119323 [Multi-domain]  Cd Length: 268  Bit Score: 65.93  E-value: 1.96e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  29 YAMLTILACGL-FVVLIAGGIDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIGVLLGLVNALLVNRLR-VPSIII 106
Cdd:cd06581     1 ILIYAILALGLnLLLGYAGQLSLGHAAFFGIGAYTAALLATRLGLPFWLALLAAGLVAALVGLLLGLPALRLRgVYFAIA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 107 TISTLNIFYGLLLWLSK------GVWLYDFPPWFekgvmlfkYTDADGYDYGLGLPLLTMIAVVLLTAFIMNfTTVGRKI 180
Cdd:cd06581    81 TLAFAEIVRLLALNWSSltggsnGLSGIPPPLLG--------GLLLSSPLAFYYLVLAVLLLVLLLLRRLVR-SPFGRAL 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 181 YAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDSlLGYELTVLAAVVLggtsLIGGRGTLSGTL 260
Cdd:cd06581   152 RAIRENEVAAEALGINVTRYKLLAFALSAALAGLAGALYAHYLGFVSPES-FGFALSIELLLMV----VLGGLGSLLGPV 226

                         250       260       270
                  ....*....|....*....|....*....|...
gi 2127473031 261 LGVILLAVMQNGLNLLGvsSYWQTLITGAIIVV 293
Cdd:cd06581   227 LGAALLVLLPELLRSLG--PGLRLLVFGLLLIL 257
TM_PBP1_LivH_like cd06582
Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two ...
 30-293 2.52e-12

Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.


Pssm-ID: 119324 [Multi-domain]  Cd Length: 272  Bit Score: 65.92  E-value: 2.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  30 AMLTILACGLFVVLIAGG-IDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIGVLLG-LVNALLVNRLR---VPSI 104
Cdd:cd06582     6 AIYALIALGLTLIFGVTGvINFAHGEFYMLGAYVAYTLLVALGLPFWLALLLALLVAALLGvLLERLVLRPLRgapLLTL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 105 IITISTLNIFYGLLLWLSKGVWLYDFPPWFEKGVMLFKYTdadgYDYGLGLPLLTMIAVVLLTAFIMNFTTVGRKIYAMG 184
Cdd:cd06582    86 LITFGGLLILLQGLLLIFGGDPRVPPPPLLSGSVELGGVT----IPPYRLFIIAVALVLLAALYLFLRRTRLGRAIRAVA 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 185 GNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAwTVMTVAPDSLLGYELTVLAAVVLGGTsliggrGTLSGTLLGVI 264
Cdd:cd06582   162 QNPEAARLLGINVRRVFALTFALGAALAGLAGVLLA-PITGVSPTMGLLLLLKAFAAVVLGGL------GSIPGAVVGGL 234

                         250       260
                  ....*....|....*....|....*....
gi 2127473031 265 LLAVMQNGLNLLGVSSYWQTLITGAIIVV 293
Cdd:cd06582   235 LLGLAESLAAAYLSSGYKDAVAFVLLILV 263
LivH COG0559
Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport ...
 30-293 1.94e-11

Branched-chain amino acid ABC-type transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440325 [Multi-domain]  Cd Length: 290  Bit Score: 63.54  E-value: 1.94e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  30 AMLTILACGLFVVL-IAGGIDISFPAMTIIAQYGMVVMLQKVGGNFAVAFVLAGGIGVLLG-LVNALLVNRLR----VPS 103
Cdd:COG0559    16 SIYALIALGLTLIFgVMGVINFAHGEFVMLGAYVAYTLATLLGLPLWLALLLAVLVAALLGvLLERLVIRPLRgappLAL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 104 IIITISTLNIFYGLLLWLSkGVWLYDFPPWFEKGVMLFKYTdadgYDYGLGLPLLTMIAVVLLTAFIMNFTTVGRKIYAM 183
Cdd:COG0559    96 LLATIGLSLVLQGLVLLIF-GADPRSFPALLSGSVELGGVS----IPAYRLFIIVVALVLLAALWLFLRRTRLGLAMRAV 170

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 184 GGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAwTVMTVAPDSLLGYELTVLAAVVLGGTsliggrGTLSGTLLGV 263
Cdd:COG0559   171 AQNREAARLMGINVDRVIALTFALGAALAGLAGVLLA-PIYSVSPTMGFLLGLKAFAAVVLGGL------GSIPGAVVGG 243

                         250       260       270
                  ....*....|....*....|....*....|
gi 2127473031 264 ILLAVMQNGLNLLGVSSYWQTLITGAIIVV 293
Cdd:COG0559   244 LLLGLAESLGAAYLPSGYKDVVAFVLLILV 273
TM_PBP1_transp_TpRbsC_like cd06580
Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. ...
 71-293 1.45e-08

Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters, which are mainly involved in the uptake of branched-chain amino acids (AAs) or in the uptake of monosaccharides including ribose, galactose, and arabinose, and which generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction.


Pssm-ID: 119322 [Multi-domain]  Cd Length: 234  Bit Score: 54.37  E-value: 1.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  71 GGNFAVAFVLAGGIGVLLGLVNALLVNRLRVPSIIITISTLNIFYGLLLWLskgvwlydfppwfekgvmlfkytdadgyd 150
Cdd:cd06580    47 TGSLPLGLLAAALAGALWALLPALLKAKLGVNEVISGLMLNYIALGLTSYL----------------------------- 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 151 yglglpLLTMIAVVLLTAFIMNFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTV-MTVAPD 229
Cdd:cd06580    98 ------LLLALLLVILVWLLLYRTRFGLRLRAVGENPRAARYAGINVKRVRLLAMLISGALAGLAGAYLVLGVqGRFTEG 171

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2127473031 230 SLLGYELTVLAAVVLGGTSLIggrgtlsGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVV 293
Cdd:cd06580   172 MSAGYGFIAIAVALLGRWNPL-------GILLAALLFGALEAGGIALQRSGGVPSELVQVLPGI 228
TM_PBP1_branched-chain-AA_like cd06574
Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette ...
 71-295 3.44e-08

Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of monosaccharides including ribose, galactose, and arabinose. These transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. This group includes Escherichia coli LivM and LivH, two TMs which heterodimerize to form the translocation pathway of the E. coli branched-chain AA LIV-1/LS transporter. This transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) and LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine. Included in this group are proteins from transport systems that contain a single TM which homodimerizes to generate the transmembrane pore; for example E. coli RbsC, AlsC, and MglC, the TMs of the high affinity ribose transporter, the D-allose transporter and the galactose transporter, respectively. The D-allose transporter may also to be involved in low affinity ribose transport.


Pssm-ID: 119320 [Multi-domain]  Cd Length: 266  Bit Score: 53.44  E-value: 3.44e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031  71 GGNFAVAFVLAGGIGVLLGLVNALLVNRLRVPSIIITISTLNIFYGLLLWLSKGvwlYDFPPWFEKGVMLFKYTDADGYD 150
Cdd:cd06574    43 GYNPWLALIAAILAGAAAGLVTGFLHTRLKINGLLAGILIMIGLYSINLRIMGG---PNIPLGTRDTLLGLLLLFGISGT 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2127473031 151 YGLGLPLLTMIAVVLLTAFIMNFTTVGRKIYAMGGNRESASRVGFSVLRLQLFVYGYMGLMSGAAGVVQAWTVMTVAPDS 230
Cdd:cd06574   120 LSIPVVLLLIVLLVLFLVIWFLRTKLGLAMRATGDNPDMARSLGINVDRTRILGLVISNALAALGGALYAQYQGFADVNM 199

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2127473031 231 LLGYELTVLAAVVLGGTSLIG--GRGTLSGTLLGVILLAVMQNGLNLLGVSSYWQTLITGAIIVVSI 295
Cdd:cd06574   200 GIGTGVIGLAAVIIGGAIVGRrtIKASILGVIIGAILYRIALALALGSGLIPSDLKLITAGVIVLVL 266
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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