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Conserved domains on  [gi|21215093|gb|AAM43872|]
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hemopexin, partial [Eulemur fulvus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HX super family cl02471
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 2-42 4.68e-03

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


The actual alignment was detected with superfamily member cd00094:

Pssm-ID: 413329 [Multi-domain]  Cd Length: 194  Bit Score: 31.90  E-value: 4.68e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 21215093   2 EEGILFFQGNRKWFWDLATRTSKERP-------WQAVGN-CSSALRWLG 42
Cdd:cd00094 110 NGKTYFFKGDKYWRYDEKTQKMDPGYpklietdFPGVPDkVDAAFRWLD 158
 
Name Accession Description Interval E-value
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 2-42 4.68e-03

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 31.90  E-value: 4.68e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 21215093   2 EEGILFFQGNRKWFWDLATRTSKERP-------WQAVGN-CSSALRWLG 42
Cdd:cd00094 110 NGKTYFFKGDKYWRYDEKTQKMDPGYpklietdFPGVPDkVDAAFRWLD 158
 
Name Accession Description Interval E-value
HX cd00094
Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. ...
 2-42 4.68e-03

Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of metalloproteinases (TIMPs). This CD contains 4 instances of the repeat.


Pssm-ID: 238046 [Multi-domain]  Cd Length: 194  Bit Score: 31.90  E-value: 4.68e-03
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 21215093   2 EEGILFFQGNRKWFWDLATRTSKERP-------WQAVGN-CSSALRWLG 42
Cdd:cd00094 110 NGKTYFFKGDKYWRYDEKTQKMDPGYpklietdFPGVPDkVDAAFRWLD 158
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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