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Conserved domains on  [gi|2118808597|ref|XP_044317761|]
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uncharacterized protein LOC123038133 [Drosophila rhopaloa]

Protein Classification

CCHC-type zinc finger protein( domain architecture ID 1000253)

CCHC-type zinc finger protein similar to human cellular nucleic acid-binding protein, a single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00368 super family cl31762
universal minicircle sequence binding protein (UMSBP); Provisional
 157-227 1.91e-11

universal minicircle sequence binding protein (UMSBP); Provisional


The actual alignment was detected with superfamily member PTZ00368:

Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 59.82  E-value: 1.91e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2118808597 157 PKRATTTREATPRTDPGNSETR-CFNCNAKGHWKRECTKPIRPPG--SCYGCGAKDHRLVECPQNKKKVENK--YN 227
Cdd:PTZ00368    7 GGVGHQSRECPNSAPAGAAKARpCYKCGEPGHLSRECPSAPGGRGerSCYNCGKTGHLSRECPEAPPGSGPRscYN 82
 
Name Accession Description Interval E-value
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 157-227 1.91e-11

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 59.82  E-value: 1.91e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2118808597 157 PKRATTTREATPRTDPGNSETR-CFNCNAKGHWKRECTKPIRPPG--SCYGCGAKDHRLVECPQNKKKVENK--YN 227
Cdd:PTZ00368    7 GGVGHQSRECPNSAPAGAAKARpCYKCGEPGHLSRECPSAPGGRGerSCYNCGKTGHLSRECPEAPPGSGPRscYN 82
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 151-220 8.35e-09

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 53.32  E-value: 8.35e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2118808597 151 FADIMLPKRATTTREATPrtdpgnsetrCFNCNAKGHWKRECTKPIrppgsCYGCGAKDHRLVECPQNKK 220
Cdd:COG5082    45 YEDRSVEDVSAIREENPV----------CFNCGQNGHLRRDCPHSI-----CYNCSWDGHRSNHCPKPKK 99
zf-CCHC pfam00098
Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following ...
 179-194 1.19e-03

Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.


Pssm-ID: 395050 [Multi-domain]  Cd Length: 18  Bit Score: 35.20  E-value: 1.19e-03
                          10
                  ....*....|....*.
gi 2118808597 179 CFNCNAKGHWKRECTK 194
Cdd:pfam00098   3 CYNCGEPGHIARDCPK 18
ZnF_C2HC smart00343
zinc finger;
178-194 1.68e-03

zinc finger;


Pssm-ID: 197667 [Multi-domain]  Cd Length: 17  Bit Score: 34.73  E-value: 1.68e-03
                           10
                   ....*....|....*..
gi 2118808597  178 RCFNCNAKGHWKRECTK 194
Cdd:smart00343   1 KCYNCGKEGHIARDCPS 17
 
Name Accession Description Interval E-value
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 157-227 1.91e-11

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 59.82  E-value: 1.91e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2118808597 157 PKRATTTREATPRTDPGNSETR-CFNCNAKGHWKRECTKPIRPPG--SCYGCGAKDHRLVECPQNKKKVENK--YN 227
Cdd:PTZ00368    7 GGVGHQSRECPNSAPAGAAKARpCYKCGEPGHLSRECPSAPGGRGerSCYNCGKTGHLSRECPEAPPGSGPRscYN 82
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 168-220 8.97e-10

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 55.20  E-value: 8.97e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2118808597 168 PRTDPGNSETRCFNCNAKGHWKRECtkPIRPPG----SCYGCGAKDHRLVECPQNKK 220
Cdd:PTZ00368   44 PSAPGGRGERSCYNCGKTGHLSREC--PEAPPGsgprSCYNCGQTGHISRECPNRAK 98
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 164-218 7.24e-09

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 52.89  E-value: 7.24e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2118808597 164 REATPRTDPGNSETRCFNCNAKGHWKRECTKPIRPPG---SCYGCGAKDHRLVECPQN 218
Cdd:PTZ00368   91 RECPNRAKGGAARRACYNCGGEGHISRDCPNAGKRPGgdkTCYNCGQTGHLSRDCPDK 148
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 151-220 8.35e-09

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 53.32  E-value: 8.35e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2118808597 151 FADIMLPKRATTTREATPrtdpgnsetrCFNCNAKGHWKRECTKPIrppgsCYGCGAKDHRLVECPQNKK 220
Cdd:COG5082    45 YEDRSVEDVSAIREENPV----------CFNCGQNGHLRRDCPHSI-----CYNCSWDGHRSNHCPKPKK 99
PTZ00368 PTZ00368
universal minicircle sequence binding protein (UMSBP); Provisional
 172-216 5.77e-07

universal minicircle sequence binding protein (UMSBP); Provisional


Pssm-ID: 173561 [Multi-domain]  Cd Length: 148  Bit Score: 47.49  E-value: 5.77e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2118808597 172 PGNSETR-CFNCNAKGHWKRECTKPIR---PPGSCYGCGAKDHRLVECP 216
Cdd:PTZ00368   72 PPGSGPRsCYNCGQTGHISRECPNRAKggaARRACYNCGGEGHISRDCP 120
AIR1 COG5082
Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational ...
 179-220 8.93e-06

Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion];


Pssm-ID: 227414 [Multi-domain]  Cd Length: 190  Bit Score: 44.84  E-value: 8.93e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2118808597 179 CFNCNAKGHWKRECTKPIRPPGSCYGCGAKDHRLVECPQNKK 220
Cdd:COG5082   100 CYNCGETGHLSRDCNPSKDQQKSCFDCNSTRHSSEDCPSIWK 141
zf-CCHC pfam00098
Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following ...
 179-194 1.19e-03

Zinc knuckle; The zinc knuckle is a zinc binding motif composed of the the following CX2CX4HX4C where X can be any amino acid. The motifs are mostly from retroviral gag proteins (nucleocapsid). Prototype structure is from HIV. Also contains members involved in eukaryotic gene regulation, such as C. elegans GLH-1. Structure is an 18-residue zinc finger.


Pssm-ID: 395050 [Multi-domain]  Cd Length: 18  Bit Score: 35.20  E-value: 1.19e-03
                          10
                  ....*....|....*.
gi 2118808597 179 CFNCNAKGHWKRECTK 194
Cdd:pfam00098   3 CYNCGEPGHIARDCPK 18
ZnF_C2HC smart00343
zinc finger;
178-194 1.68e-03

zinc finger;


Pssm-ID: 197667 [Multi-domain]  Cd Length: 17  Bit Score: 34.73  E-value: 1.68e-03
                           10
                   ....*....|....*..
gi 2118808597  178 RCFNCNAKGHWKRECTK 194
Cdd:smart00343   1 KCYNCGKEGHIARDCPS 17
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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