NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2112720817|gb|KAH1025469|]
View 

hypothetical protein HUJ05_010191 [Dendroctonus ponderosae]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
COX17 pfam05051
Cytochrome C oxidase copper chaperone (COX17); Cox17 is essential for the assembly of ...
 490-535 5.16e-24

Cytochrome C oxidase copper chaperone (COX17); Cox17 is essential for the assembly of functional cytochrome c oxidase (CCO) and for delivery of copper ions to the mitochondrion for insertion into the enzyme in yeast. The structure of Cox17 shows the protein to have an unstructured N-terminal region followed by two helices and several unstructured C-terminal residues. The Cu(I) binding site has been modelled as two-coordinate with ligation by conserved residues Cys23 and Cys26.


:

Pssm-ID: 428283  Cd Length: 47  Bit Score: 94.55  E-value: 5.16e-24
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2112720817 490 KKLKPCCACPETKKVRDQCIIENG-EENCKDLIEAHKKCMRDLGFNI 535
Cdd:pfam05051   1 KKPKPCCACPETKKARDECILFNGaEEKCKDLIEAHKACMRGYGFKI 47
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 1-43 3.75e-10

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


:

Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 55.24  E-value: 3.75e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2112720817    1 MDFARQQLEKYGWNEGKGLGRAENGISQAIKPKLKFDNAGIGH 43
Cdd:smart00443   4 SNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKKDRKGLGA 46
 
Name Accession Description Interval E-value
COX17 pfam05051
Cytochrome C oxidase copper chaperone (COX17); Cox17 is essential for the assembly of ...
 490-535 5.16e-24

Cytochrome C oxidase copper chaperone (COX17); Cox17 is essential for the assembly of functional cytochrome c oxidase (CCO) and for delivery of copper ions to the mitochondrion for insertion into the enzyme in yeast. The structure of Cox17 shows the protein to have an unstructured N-terminal region followed by two helices and several unstructured C-terminal residues. The Cu(I) binding site has been modelled as two-coordinate with ligation by conserved residues Cys23 and Cys26.


Pssm-ID: 428283  Cd Length: 47  Bit Score: 94.55  E-value: 5.16e-24
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2112720817 490 KKLKPCCACPETKKVRDQCIIENG-EENCKDLIEAHKKCMRDLGFNI 535
Cdd:pfam05051   1 KKPKPCCACPETKKARDECILFNGaEEKCKDLIEAHKACMRGYGFKI 47
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 1-43 3.75e-10

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 55.24  E-value: 3.75e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2112720817    1 MDFARQQLEKYGWNEGKGLGRAENGISQAIKPKLKFDNAGIGH 43
Cdd:smart00443   4 SNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKKDRKGLGA 46
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 3-44 1.02e-09

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 54.05  E-value: 1.02e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2112720817   3 FARQQLEKYGWNEGKGLGRAENGISQAIKPKLKFDNAGIGHD 44
Cdd:pfam01585   4 IGFKLLQKMGWKEGQGLGKNEQGIAEPIEAKIKKDRRGLGAE 45
 
Name Accession Description Interval E-value
COX17 pfam05051
Cytochrome C oxidase copper chaperone (COX17); Cox17 is essential for the assembly of ...
 490-535 5.16e-24

Cytochrome C oxidase copper chaperone (COX17); Cox17 is essential for the assembly of functional cytochrome c oxidase (CCO) and for delivery of copper ions to the mitochondrion for insertion into the enzyme in yeast. The structure of Cox17 shows the protein to have an unstructured N-terminal region followed by two helices and several unstructured C-terminal residues. The Cu(I) binding site has been modelled as two-coordinate with ligation by conserved residues Cys23 and Cys26.


Pssm-ID: 428283  Cd Length: 47  Bit Score: 94.55  E-value: 5.16e-24
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2112720817 490 KKLKPCCACPETKKVRDQCIIENG-EENCKDLIEAHKKCMRDLGFNI 535
Cdd:pfam05051   1 KKPKPCCACPETKKARDECILFNGaEEKCKDLIEAHKACMRGYGFKI 47
G_patch smart00443
glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in ...
 1-43 3.75e-10

glycine rich nucleic binding domain; A predicted glycine rich nucleic binding domain found in the splicing factor 45, SON DNA binding protein and D-type Retrovirus- polyproteins.


Pssm-ID: 197727 [Multi-domain]  Cd Length: 47  Bit Score: 55.24  E-value: 3.75e-10
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 2112720817    1 MDFARQQLEKYGWNEGKGLGRAENGISQAIKPKLKFDNAGIGH 43
Cdd:smart00443   4 SNIGAKLLRKMGWKEGQGLGKNEQGIVEPISAEIKKDRKGLGA 46
G-patch pfam01585
G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in ...
 3-44 1.02e-09

G-patch domain; This domain is found in a number of RNA binding proteins, and is also found in proteins that contain RNA binding domains. This suggests that this domain may have an RNA binding function. This domain has seven highly conserved glycines.


Pssm-ID: 396249 [Multi-domain]  Cd Length: 45  Bit Score: 54.05  E-value: 1.02e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 2112720817   3 FARQQLEKYGWNEGKGLGRAENGISQAIKPKLKFDNAGIGHD 44
Cdd:pfam01585   4 IGFKLLQKMGWKEGQGLGKNEQGIAEPIEAKIKKDRRGLGAE 45
G-patch_2 pfam12656
G-patch domain; Yeast Spp2, a G-patch protein and spliceosome component, interacts with the ...
 2-47 5.77e-04

G-patch domain; Yeast Spp2, a G-patch protein and spliceosome component, interacts with the ATP-dependent DExH-box splicing factor Prp2. As this interaction involves the G-patch sequence in Spp2 and is required for the recruitment of Prp2 to the spliceosome before the first catalytic step of splicing, it is proposed that Spp2 might be an accessory factor that confers spliceosome specificity on Prp2.


Pssm-ID: 432700 [Multi-domain]  Cd Length: 61  Bit Score: 38.03  E-value: 5.77e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2112720817   2 DFARQQLEKYGWNEGKGLGRAENGISQAIKPKLKFDNAGIGHDAAE 47
Cdd:pfam12656  16 EFGAAMLRGMGWKPGQGIGKNKKGDVKPKEYKRRPGGLGLGAKPAE 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH