|
Name |
Accession |
Description |
Interval |
E-value |
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
36-426 |
4.75e-123 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 361.78 E-value: 4.75e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 36 RYKKAIEEFEKIFGESDVEIYSAPGRCEVGGNHTDHQNGMVLATSINQDALAVVGRSEDGMIHVLSDGY-EMVDVDVNDL 114
Cdd:COG0153 1 RLERLIEAFEEAFGEEPEGVFSAPGRVNLIGEHTDYNGGFVLPAAIDRGTYAAARPRDDRKVRVYSADFdEEVEFDLDDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 115 EerYDEEGTTAALVRGVAAELKARGYEVQGYNAYIVSDVLIGAGLSSSAAFEVILGTIISGLFNEGsIDPVVIAQTGQYA 194
Cdd:COG0153 81 E--PGEEDGWANYVRGVAWALQERGYKLGGFDLVIDGDVPLGAGLSSSAALEVAVALALNDLFGLG-LDPVELAKIGQRA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 195 ENVYFGKPCGLMDQMACSVGGMIHIDFKEPGSPVVEKVPSDFEsyQYSMCIVDTKASHADMGDDYASIPEEMKKVAKFFG 274
Cdd:COG0153 158 ENEFVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLPLE--GYALVIVDTNVKHSLADSEYNERRAECEAAAAILG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 275 KTYLREVEEDDFykqiSGLRSVLGDRPI-LRALHFFEEERRVEGEVKALRDGDFKEFLELVKDSGNSSFKYLQniyNSTN 353
Cdd:COG0153 236 VKSLRDVTLEDL----EAARARLGDEVLrRRARHVVTENQRVLEAVEALRAGDLEAFGKLMNASHASLRDDYE---VSCP 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2104885332 354 VQKQAMSIALAVSDkilrkHGVSRVHGGGFAGTIEIFVENSFVDEYKARMDRVFGKGS---CQILKVRQSGGRRVL 426
Cdd:COG0153 309 ELDTLVELALAEAG-----VLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEKTglePDFYVVKPSDGARRL 379
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
39-400 |
3.99e-37 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 139.19 E-value: 3.99e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 39 KAIEEFEKIFGESDVEIYSAPGRCEVGGNHTDHQNGMVLATSINQDALAVVGRSEDGMIHVLSDGYEM-VDVDVNDLEER 117
Cdd:TIGR00131 3 SIQKIFASAFGAKPDFTARAPGRVNLIGEHTDYNDGSVLPCAIDFGTLCAVAVRDDKNVRIYLANADNkFAERSLDLPLD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 118 YDEEGTTAALVRGVAAELKARGYEV-QGYNAYIVSDVLIGAGLSSSAAFEVILGTIISGLFnEGSIDPVVIAQTGQYAEN 196
Cdd:TIGR00131 83 GSEVSDWANYFKGVLHVAQERFNSFpLGADIVCSGNVPTGSGLSSSAAFECAVGAVLQNMG-HLPLDSKQILLRIQVAEN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 197 VYFGKPCGLMDQMACSVGGMIH---IDFKEpgspvVEKVPSDFESYQYSMCIVDTKASHADMGDDYASIPEEMKKVAKFF 273
Cdd:TIGR00131 162 HFVGVNCGIMDQAASVLGKEDHallVECRS-----LKATPFKFPQLGIAFVIANTNVKRTLAPSNYNTRRQECTTAANFL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 274 GKTY---LREVEEDDFYKQISGLRSVLgdrPIL--RALHFFEEERRVEGEVKALRDGDFKEFLELVKDSGNSsfkyLQNI 348
Cdd:TIGR00131 237 AATDkgaLRDFMNEYFARYIARLTKML---PLVeeRAKHVVSENLRVLKAVKAMKDNDFKQFGALMNESHAS----CDDD 309
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2104885332 349 YNSTNVQ--KQAMSIALAVSDkilrkhGVSRVHGGGFAGTIEIFVENSFVDEYK 400
Cdd:TIGR00131 310 YECTCPEidELVCSAALVNGS------GGSRMTGAGFGGCTVHLVPNENVDKVR 357
|
|
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
41-402 |
1.97e-36 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 137.30 E-value: 1.97e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 41 IEEFEKIFGESDVEIYSAPGRCEVGGNHTDHQNGMVLATSINQDALAVVGRSEDGMIHVLSDGYE---MVDVDVNDLeeR 117
Cdd:PRK05322 7 KKKFAEVFGEEAEDVFFSPGRINLIGEHTDYNGGHVFPAAITLGTYGAARKRDDKKVRLYSANFEdlgIIEFDLDDL--S 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 118 YDEEGTTAALVRGVAAELKARGYEV-QGYNAYIVSDVLIGAGLSSSAAFEVILGTIISGLFNEGsIDPVVIAQTGQYAEN 196
Cdd:PRK05322 85 FDKEDDWANYPKGVLKFLQEAGYKIdHGFDILIYGNIPNGAGLSSSASIELLTGVILKDLFNLD-LDRLELVKLGQKTEN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 197 VYFGKPCGLMDQMACSVGGMIHIDFKEPGSPVVEKVPSDFESyqYSMCIVDTKASHADMGDDY----ASIPEEMKKVAKF 272
Cdd:PRK05322 164 EFIGVNSGIMDQFAIGMGKKDHAILLDCNTLEYEYVPLDLGD--YVIVIMNTNKRRELADSKYnerrAECEKALEELQKK 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 273 FGKTYLREVEEDDFYKqisgLRSVLGDRPIL-RALHFFEEERRVEGEVKALRDGDFKEFLELVKDSGNSsfkyLQNIYNS 351
Cdd:PRK05322 242 LDIKSLGELTEEEFDE----YSYLIKDETLLkRARHAVTENQRTLKAVKALKAGDLEKFGRLMNASHVS----LRDDYEV 313
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2104885332 352 TNVQKQAMsIALAvsdkiLRKHGV--SRVHGGGFAG-TIEIfVENSFVDEYKAR 402
Cdd:PRK05322 314 TGLELDTL-VEAA-----WKQEGVlgARMTGAGFGGcAIAI-VKKDKVEAFKEN 360
|
|
| GalKase_gal_bdg |
pfam10509 |
Galactokinase galactose-binding signature; This is the highly conserved galactokinase ... |
42-91 |
1.74e-17 |
|
Galactokinase galactose-binding signature; This is the highly conserved galactokinase signature sequence which appears to be present in all galactokinases irrespective of how many other ATP binding sites, etc that they carry. The function of this domain appears to be to bind galactose, and the domain is normally at the N-terminus of the enzymes, EC:2.7.1.6. This domain is associated with the families GHMP_kinases_C, pfam08544 and GHMP_kinases_N, pfam00288.
Pssm-ID: 463125 [Multi-domain] Cd Length: 50 Bit Score: 75.57 E-value: 1.74e-17
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 2104885332 42 EEFEKIFGESDVEIYSAPGRCEVGGNHTDHQNGMVLATSINQDALAVVGR 91
Cdd:pfam10509 1 EAFEELFGKEPVGVASAPGRVNLIGEHTDYNGGFVLPAAINLDTYVAVSP 50
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
36-426 |
4.75e-123 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 361.78 E-value: 4.75e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 36 RYKKAIEEFEKIFGESDVEIYSAPGRCEVGGNHTDHQNGMVLATSINQDALAVVGRSEDGMIHVLSDGY-EMVDVDVNDL 114
Cdd:COG0153 1 RLERLIEAFEEAFGEEPEGVFSAPGRVNLIGEHTDYNGGFVLPAAIDRGTYAAARPRDDRKVRVYSADFdEEVEFDLDDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 115 EerYDEEGTTAALVRGVAAELKARGYEVQGYNAYIVSDVLIGAGLSSSAAFEVILGTIISGLFNEGsIDPVVIAQTGQYA 194
Cdd:COG0153 81 E--PGEEDGWANYVRGVAWALQERGYKLGGFDLVIDGDVPLGAGLSSSAALEVAVALALNDLFGLG-LDPVELAKIGQRA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 195 ENVYFGKPCGLMDQMACSVGGMIHIDFKEPGSPVVEKVPSDFEsyQYSMCIVDTKASHADMGDDYASIPEEMKKVAKFFG 274
Cdd:COG0153 158 ENEFVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLPLE--GYALVIVDTNVKHSLADSEYNERRAECEAAAAILG 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 275 KTYLREVEEDDFykqiSGLRSVLGDRPI-LRALHFFEEERRVEGEVKALRDGDFKEFLELVKDSGNSSFKYLQniyNSTN 353
Cdd:COG0153 236 VKSLRDVTLEDL----EAARARLGDEVLrRRARHVVTENQRVLEAVEALRAGDLEAFGKLMNASHASLRDDYE---VSCP 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2104885332 354 VQKQAMSIALAVSDkilrkHGVSRVHGGGFAGTIEIFVENSFVDEYKARMDRVFGKGS---CQILKVRQSGGRRVL 426
Cdd:COG0153 309 ELDTLVELALAEAG-----VLGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEKTglePDFYVVKPSDGARRL 379
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
39-400 |
3.99e-37 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 139.19 E-value: 3.99e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 39 KAIEEFEKIFGESDVEIYSAPGRCEVGGNHTDHQNGMVLATSINQDALAVVGRSEDGMIHVLSDGYEM-VDVDVNDLEER 117
Cdd:TIGR00131 3 SIQKIFASAFGAKPDFTARAPGRVNLIGEHTDYNDGSVLPCAIDFGTLCAVAVRDDKNVRIYLANADNkFAERSLDLPLD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 118 YDEEGTTAALVRGVAAELKARGYEV-QGYNAYIVSDVLIGAGLSSSAAFEVILGTIISGLFnEGSIDPVVIAQTGQYAEN 196
Cdd:TIGR00131 83 GSEVSDWANYFKGVLHVAQERFNSFpLGADIVCSGNVPTGSGLSSSAAFECAVGAVLQNMG-HLPLDSKQILLRIQVAEN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 197 VYFGKPCGLMDQMACSVGGMIH---IDFKEpgspvVEKVPSDFESYQYSMCIVDTKASHADMGDDYASIPEEMKKVAKFF 273
Cdd:TIGR00131 162 HFVGVNCGIMDQAASVLGKEDHallVECRS-----LKATPFKFPQLGIAFVIANTNVKRTLAPSNYNTRRQECTTAANFL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 274 GKTY---LREVEEDDFYKQISGLRSVLgdrPIL--RALHFFEEERRVEGEVKALRDGDFKEFLELVKDSGNSsfkyLQNI 348
Cdd:TIGR00131 237 AATDkgaLRDFMNEYFARYIARLTKML---PLVeeRAKHVVSENLRVLKAVKAMKDNDFKQFGALMNESHAS----CDDD 309
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2104885332 349 YNSTNVQ--KQAMSIALAVSDkilrkhGVSRVHGGGFAGTIEIFVENSFVDEYK 400
Cdd:TIGR00131 310 YECTCPEidELVCSAALVNGS------GGSRMTGAGFGGCTVHLVPNENVDKVR 357
|
|
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
41-402 |
1.97e-36 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 137.30 E-value: 1.97e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 41 IEEFEKIFGESDVEIYSAPGRCEVGGNHTDHQNGMVLATSINQDALAVVGRSEDGMIHVLSDGYE---MVDVDVNDLeeR 117
Cdd:PRK05322 7 KKKFAEVFGEEAEDVFFSPGRINLIGEHTDYNGGHVFPAAITLGTYGAARKRDDKKVRLYSANFEdlgIIEFDLDDL--S 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 118 YDEEGTTAALVRGVAAELKARGYEV-QGYNAYIVSDVLIGAGLSSSAAFEVILGTIISGLFNEGsIDPVVIAQTGQYAEN 196
Cdd:PRK05322 85 FDKEDDWANYPKGVLKFLQEAGYKIdHGFDILIYGNIPNGAGLSSSASIELLTGVILKDLFNLD-LDRLELVKLGQKTEN 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 197 VYFGKPCGLMDQMACSVGGMIHIDFKEPGSPVVEKVPSDFESyqYSMCIVDTKASHADMGDDY----ASIPEEMKKVAKF 272
Cdd:PRK05322 164 EFIGVNSGIMDQFAIGMGKKDHAILLDCNTLEYEYVPLDLGD--YVIVIMNTNKRRELADSKYnerrAECEKALEELQKK 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 273 FGKTYLREVEEDDFYKqisgLRSVLGDRPIL-RALHFFEEERRVEGEVKALRDGDFKEFLELVKDSGNSsfkyLQNIYNS 351
Cdd:PRK05322 242 LDIKSLGELTEEEFDE----YSYLIKDETLLkRARHAVTENQRTLKAVKALKAGDLEKFGRLMNASHVS----LRDDYEV 313
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 2104885332 352 TNVQKQAMsIALAvsdkiLRKHGV--SRVHGGGFAG-TIEIfVENSFVDEYKAR 402
Cdd:PRK05322 314 TGLELDTL-VEAA-----WKQEGVlgARMTGAGFGGcAIAI-VKKDKVEAFKEN 360
|
|
| PRK05101 |
PRK05101 |
galactokinase; Provisional |
44-401 |
6.86e-35 |
|
galactokinase; Provisional
Pssm-ID: 179937 [Multi-domain] Cd Length: 382 Bit Score: 133.12 E-value: 6.86e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 44 FEKIFGESDVEIYSAPGRCEVGGNHTDHQNGMVLATSIN-QDALAVVGRsEDGMIHVLSDGYEMvDVDVNDLEE--RYDE 120
Cdd:PRK05101 11 FAQQFGYPPTHTIQAPGRVNLIGEHTDYNDGFVLPCAIDyQTVISCAKR-DDRIVRVIAADYDN-QQDEFSLDApiVPHP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 121 EGTTAALVRGVAAELKARGYEVQGYNAYIVSDVLIGAGLSSSAAFEVILGTIISGLFNEGsIDPVVIAQTGQYAENVYFG 200
Cdd:PRK05101 89 EQQWANYVRGVVKHLQERNPDFGGADLVISGNVPQGAGLSSSASLEVAVGQTFQQLYHLP-LSGAEIALNGQEAENQFVG 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 201 KPCGLMDQMACSVGGMIH---IDFKEPGSPVVeKVPSDfesyqYSMCIVDTKASHADMGDDYASIPEEMKKVAKFFGKTY 277
Cdd:PRK05101 168 CNCGIMDQLISALGKKDHallIDCRSLETKAV-PMPEG-----VAVVIINSNVKRGLVDSEYNTRRQQCETAARFFGVKA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 278 LREVEEDDFYKQISGLRSVLGDrpilRALHFFEEERRVEGEVKALRDGDFKEFLELVKDSGNSsfkyLQNIYNSTNVQkq 357
Cdd:PRK05101 242 LRDVTLEQFNAVAAELDPVVAK----RARHVITENARTLEAASALAAGDLKRMGELMAESHAS----MRDDFEITVPQ-- 311
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 2104885332 358 amsIALAVS--DKILRKHGVSRVHGGGFAGTIEIFVENSFVDEYKA 401
Cdd:PRK05101 312 ---IDTLVEivKAVIGDQGGVRMTGGGFGGCIVALVPEELVEAVRQ 354
|
|
| PRK00555 |
PRK00555 |
galactokinase; Provisional |
56-397 |
9.91e-35 |
|
galactokinase; Provisional
Pssm-ID: 179063 [Multi-domain] Cd Length: 363 Bit Score: 132.29 E-value: 9.91e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 56 YSAPGRCEVGGNHTDHQNGMVLATSINQDALAVVGRSEDGMIHVLS---DGYEMVDVDVNdleerydeEGTT---AALVR 129
Cdd:PRK00555 5 YAAPGRINLIGEHTDYNLGFALPIALPQRTVVTFTPEHTDAITASSdraDGSARIPLDTT--------PGQVtgwAAYAA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 130 GVAAELKARGYEVQGYNAYIVSDVLIGAGLSSSAAFE-VILGTIISGLFNEgsIDPVVIAQTGQYAENVYFGKPCGLMDQ 208
Cdd:PRK00555 77 GVIWALRGAGHPVPGGAMSITSDVEIGSGLSSSAALEcAVLGAVGAATGTR--IDRLEQARLAQRAENEYVGAPTGLLDQ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 209 MACSVGG---MIHIDFKEPGspvVEKVPSDFESYQYSMCIVDTKASHADMGDDYASIPEEMKKVAKFFGKTYLREVEEdd 285
Cdd:PRK00555 155 LAALFGApktALLIDFRDLT---VRPVAFDPDAAGVVLLLMDSRARHRHAGGEYAARRASCERAAADLGVSSLRAVQD-- 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 286 fyKQISGLRSVLGDRPILRALHFFEEERRVEGEVKALRDGDFKEFLELVKDSGNSsfkyLQNIYNSTNVQkqamsIALaV 365
Cdd:PRK00555 230 --RGLAALGAIADPIDARRARHVLTENQRVLDFAAALADSDFTAAGQLLTASHAS----MRDDFEITTER-----IDL-I 297
|
330 340 350
....*....|....*....|....*....|...
gi 2104885332 366 SDKILRKHGV-SRVHGGGFAGTIEIFVENSFVD 397
Cdd:PRK00555 298 ADSAVRAGALgARMTGGGFGGCVIALVPADRAE 330
|
|
| PRK03817 |
PRK03817 |
galactokinase; Provisional |
56-426 |
2.73e-31 |
|
galactokinase; Provisional
Pssm-ID: 235163 [Multi-domain] Cd Length: 351 Bit Score: 122.41 E-value: 2.73e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 56 YSAPGRCEVGGNHTDHQNGMVLATSINQdaLAVVGRSEDGMIHVLSDGY-EMVDVDVNDLEErydeEGTTAALVRGVAAE 134
Cdd:PRK03817 3 VKSPGRVNLIGEHTDYNDGYVLPFAINL--YTFLEIEKSEKFIFYSENFnEEKTFELDKLEK----LNSWADYIKGVIWV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 135 LKARGYEVQGYNAYIVSDVLIGAGLSSSAAFEVILGTIISGLFNEGsIDPVVIAQTGQYAENVYFGKPCGLMDQMACSVG 214
Cdd:PRK03817 77 LEKRGYEVGGVKGKVSSNLPIGAGLSSSASLEVAVAYALNEAYNLN-LSKLELALLAREAENEFVGVPCGIMDQFAVAFG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 215 GMIHIDFKEPGSPVVEKVPSDFEsyqYSMCIVDTKASHADMGDDYASIPEEMKKVAKFFGKTYLREVEEDDFYKQISGLR 294
Cdd:PRK03817 156 KKDHAIFLDTMTLEYEYVPFPED---YEILVFDTGVKRELASSEYNERRQECEEALKILGKKSSKEVTEEDLSKLPPLLR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 295 SvlgdrpilRALHFFEEERRVEGEVKALRDGDFKEFLELVKDSGNSsfkyLQNIYNstnvqkqamsialaVS----DKI- 369
Cdd:PRK03817 233 K--------RAGYVLRENERVLKVRDALKEGDIETLGELLTESHWD----LADNYE--------------VSceelDFFv 286
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2104885332 370 --LRKHGV--SRVHGGGFAGTIEIFVEN----SFVDEYKARMDRVFGKgSCQILKVRQSGGRRVL 426
Cdd:PRK03817 287 efALELGAygARLTGAGFGGSAIALVDKgkfeSIGEELLEEYKKRFGI-DPKYFVVESSDGVRKI 350
|
|
| PLN02865 |
PLN02865 |
galactokinase |
49-398 |
1.13e-18 |
|
galactokinase
Pssm-ID: 215466 [Multi-domain] Cd Length: 423 Bit Score: 87.55 E-value: 1.13e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 49 GESDVEIYSAPGR-CEVGGnHTDHQNGMVLATSINQDALAVVGRSEDGMIHVLSDGYE-MVDVDVNDLE-------ERYD 119
Cdd:PLN02865 26 NSGEVRVVVSPYRiCPLGA-HIDHQGGTVSAMTINKGILLGFVPSGDPEVLLRSAQFEgEVRFRVDEIQhpianvsSDSK 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 120 EEGTTAALVRGVAAELKARGYEV-QGYNAYIV-SDVLIGAGLSSSAAFEVILGTIISGLfNEGSIDPVVIAQTGQYAENV 197
Cdd:PLN02865 105 EESNWGDYARGAVYALQSRGHALsQGITGYISgSEGLDSSGLSSSAAVGVAYLLALENA-NNLTVSPEDNIELDRLIENE 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 198 YFGKPCGLMDQMA---CSVGGMIHIDFKEPGSpvvEKVPSDFESYQ----YSMCIVDTKASHA-DMGDDYASIPEEMKKV 269
Cdd:PLN02865 184 YLGLRNGILDQSAillSRYGCLTFMDCKTLDH---KLVSLQFQQPGgekpFKILLAFSGLRHAlTNKPGYNLRVSECQEA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 270 AKFF----GKTYLREVEEDDFYKQISGLRSVLGDRPILRALHFFEEERRVEGEVKALRDGDFKEFLELVKDSGNSSfkyL 345
Cdd:PLN02865 261 ARFLleasGNDELEPLLCNVEPEVYEAHKCKLEAVLARRAEHYFSENMRVIKGVEAWASGNLEEFGKLISASGLSS---I 337
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 2104885332 346 QNIYNSTNVQKQAMSIAlavsdkiLRKHGV--SRVHGGGFAGTIEIFVENSFVDE 398
Cdd:PLN02865 338 ENYECGCEPLIQLYEIL-------LKAPGVygARFSGAGFRGCCVAFVDAEMAEE 385
|
|
| GalKase_gal_bdg |
pfam10509 |
Galactokinase galactose-binding signature; This is the highly conserved galactokinase ... |
42-91 |
1.74e-17 |
|
Galactokinase galactose-binding signature; This is the highly conserved galactokinase signature sequence which appears to be present in all galactokinases irrespective of how many other ATP binding sites, etc that they carry. The function of this domain appears to be to bind galactose, and the domain is normally at the N-terminus of the enzymes, EC:2.7.1.6. This domain is associated with the families GHMP_kinases_C, pfam08544 and GHMP_kinases_N, pfam00288.
Pssm-ID: 463125 [Multi-domain] Cd Length: 50 Bit Score: 75.57 E-value: 1.74e-17
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 2104885332 42 EEFEKIFGESDVEIYSAPGRCEVGGNHTDHQNGMVLATSINQDALAVVGR 91
Cdd:pfam10509 1 EAFEELFGKEPVGVASAPGRVNLIGEHTDYNGGFVLPAAINLDTYVAVSP 50
|
|
| PLN02521 |
PLN02521 |
galactokinase |
20-221 |
8.20e-13 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 69.74 E-value: 8.20e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 20 LKEIYVDESVLDYQRKRYKKAIEEFEKIFGeSDVEIYS-APGRCEVGGNHTDHQNGMVLATSINQDALAVVGRSE-DGMI 97
Cdd:PLN02521 15 LEPVYGDGSLLEEARLRYARLKAAFVEVYG-AKPDLFArSPGRVNLIGEHIDYEGYSVLPMAIRQDTIVAIRRAEgSKKL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 98 HV--LSDGYEMVDVDVNDleeryDEEGTTAALV---------RGVAAELKARGYEVQ---GYNAYIVSDVLIGAGLSSSA 163
Cdd:PLN02521 94 RIanVNDKYTTCTFPADP-----DQEVDLANHKwgnyficgyKGVFEFLKSKGVDVGppvGLDVVVDGTVPTGSGLSSSA 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2104885332 164 AFeVILGTI-ISGLFNEgSIDPVVIAQTGQYAENvYFGKPCGLMDQmACSVGGMI----HIDF 221
Cdd:PLN02521 169 AL-VCSAAIaIMAALGL-NFTKKEVAQFTCKCER-HIGTQSGGMDQ-AISIMAQQgvakLIDF 227
|
|
| ERG12 |
COG1577 |
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ... |
58-364 |
1.16e-12 |
|
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 441185 [Multi-domain] Cd Length: 277 Bit Score: 67.95 E-value: 1.16e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 58 APGRCEVGGNHTDHQNGMVLATSINQDALAVVGRSEDGMIHVLSDGYEmvdvdvNDLEERYDEEGTTAALVRGVAAELKA 137
Cdd:COG1577 1 APGKLILFGEHAVVYGQPAIAVAVDRRATVTVEPSDDDKLRIESPDLG------GTLDLDPLADAALRYIKAAIEAALEY 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 138 RGYEVQGYNAYIVSDVLIGAGLSSSAAfeVILGTI--ISGLFNEgSIDPVVIAQTGQYAENVYFGKPCGlMDQMACSVGG 215
Cdd:COG1577 75 LGLPLKGFDIEIDSEIPRKRGLGSSAA--VAVAVIraLAAFYGV-ELSKEELFKLALEAEKIVHGNPSG-LDTAASTYGG 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 216 MIHIDFKEPGSPVveKVPSDFesyqySMCIVDTKAShadmgddyASIPEEMKKVAKFFGKtylREVEEDDFYKQISGLrs 295
Cdd:COG1577 151 PIYYQRGDRAEPL--ELPKNL-----PLVVGDTGVP--------ASTKELVAKVRKLKER---NPELYEAFLEEIGDL-- 210
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2104885332 296 vlgdrpILRALhffeeerrvegevKALRDGDFKEFLELVkdsgNSSFKYLQNIYNSTNVQKQAMSIALA 364
Cdd:COG1577 211 ------VEEAI-------------EALEEGDLEALGELM----NENHGLLRALGVSTPELDRLVEAARK 256
|
|
| GHMP_kinases_N |
pfam00288 |
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ... |
148-215 |
1.58e-08 |
|
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 395225 [Multi-domain] Cd Length: 64 Bit Score: 51.01 E-value: 1.58e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2104885332 148 YIVSDVLIGAGLSSSAAFEVILGTIISGLFNEGsidpvvIAQTGQYAENVYFGKPCGLMDQMACSVGG 215
Cdd:pfam00288 3 EIESNIPLGAGLGSSAALAVALLLALNELFGLP------LAKLALEAEELAGGGRGGGMDVAASLYGG 64
|
|
| PTZ00290 |
PTZ00290 |
galactokinase; Provisional |
30-210 |
4.74e-06 |
|
galactokinase; Provisional
Pssm-ID: 240347 [Multi-domain] Cd Length: 468 Bit Score: 48.67 E-value: 4.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 30 LDYQRKRYKKAIEEFEKIF-------GESDVE--IYS-APGRCEVGGNHTDHQNGMVLATSINQDALAVVGRS---EDGM 96
Cdd:PTZ00290 4 ESYSDERLDSTLSTLKPIFletfkveNDADVEwlLFTfAPGRVNFIGEHVDYMGGYVCPAAVLEGCHILVGRVkhfCDHK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2104885332 97 IHVLSDGYEMVDVDvNDLEERYDEEGTTaaLVRGVAA-ELKARGY-----EVQGYNAYIVSDVLIGAGLSSSAAFEVIL- 169
Cdd:PTZ00290 84 LRFATETDEHFVLD-HLGGAKHNKAWTT--FVRGAATlRLNRLGVaidapSLQGVCMVVHGTLPMGAGMSASASFGVALl 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2104885332 170 ---GTIISGLFNEGSIDP---------------VVIAQTGQYAENVYFGKPCGLMDQMA 210
Cdd:PTZ00290 161 naiNTVVTRRYKGCPTSPgrrysilppmskeelIELAKQARRIETEFCGVNVGIMDQFI 219
|
|
|